locus-tag	class	description
SPH21_RS00010	PF11638	DnaA N-terminal domain
SPH21_RS00010	PF08299	Bacterial dnaA protein helix-turn-helix
SPH21_RS00010	PF00308	Bacterial dnaA  protein
SPH21_RS00015	PF00011	Hsp20/alpha crystallin family
SPH21_RS00025	PF01521	Iron-sulphur cluster biosynthesis
SPH21_RS00030	PF02826	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
SPH21_RS00030	PF00389	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
SPH21_RS00035	PF00398	Ribosomal RNA adenine dimethylase
SPH21_RS00040	PF04166	Pyridoxal phosphate biosynthetic protein PdxA
SPH21_RS00050	PF02504	Fatty acid synthesis protein
SPH21_RS00055	PF08545	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
SPH21_RS00055	PF08541	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal  
SPH21_RS00060	PF00364	Biotin-requiring enzyme
SPH21_RS00065	PF00289	Biotin carboxylase, N-terminal domain
SPH21_RS00065	PF02786	Carbamoyl-phosphate synthase L chain, ATP binding domain
SPH21_RS00065	PF02785	Biotin carboxylase C-terminal domain
SPH21_RS00070	PF00902	Sec-independent protein translocase protein (TatC)
SPH21_RS00075	PF02502	Ribose/Galactose Isomerase
SPH21_RS00085	PF02589	LUD domain
SPH21_RS00085	PF13183	4Fe-4S dicluster domain
SPH21_RS00085	PF11870	Domain of unknown function (DUF3390)
SPH21_RS00095	PF02771	Acyl-CoA dehydrogenase, N-terminal domain
SPH21_RS00095	PF00441	Acyl-CoA dehydrogenase, C-terminal domain
SPH21_RS00095	PF02770	Acyl-CoA dehydrogenase, middle domain
SPH21_RS00100	PF00108	Thiolase, N-terminal domain
SPH21_RS00100	PF02803	Thiolase, C-terminal domain
SPH21_RS00105	PF02737	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
SPH21_RS00105	PF00378	Enoyl-CoA hydratase/isomerase
SPH21_RS00105	PF00725	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
SPH21_RS00120	PF00501	AMP-binding enzyme
SPH21_RS00135	PF13533	Biotin-lipoyl like
SPH21_RS00140	PF00873	AcrB/AcrD/AcrF family
SPH21_RS00155	PF00255	Glutathione peroxidase
SPH21_RS00190	PF01483	Proprotein convertase P-domain
SPH21_RS00190	PF04389	Peptidase family M28
SPH21_RS00195	PF02565	Recombination protein O C terminal
SPH21_RS00195	PF11967	Recombination protein O N terminal
SPH21_RS00200	PF01219	Prokaryotic diacylglycerol kinase
SPH21_RS00210	PF08264	Anticodon-binding domain of tRNA
SPH21_RS00210	PF00133	tRNA synthetases class I (I, L, M and V)
SPH21_RS00215	PF01258	Prokaryotic dksA/traR C4-type zinc finger
SPH21_RS00220	PF01252	Signal peptidase (SPase) II
SPH21_RS00230	PF00694	Aconitase C-terminal domain
SPH21_RS00230	PF00330	Aconitase family (aconitate hydratase)
SPH21_RS00240	PF03120	NAD-dependent DNA ligase OB-fold domain
SPH21_RS00240	PF03119	NAD-dependent DNA ligase C4 zinc finger domain
SPH21_RS00240	PF01653	NAD-dependent DNA ligase adenylation domain
SPH21_RS00240	PF00533	BRCA1 C Terminus (BRCT) domain
SPH21_RS00240	PF12826	Helix-hairpin-helix motif
SPH21_RS00245	PF00701	Dihydrodipicolinate synthetase family
SPH21_RS00250	PF00155	Aminotransferase class I and II
SPH21_RS00255	PF12327	FtsZ family, C-terminal domain
SPH21_RS00255	PF00091	Tubulin/FtsZ family, GTPase domain
SPH21_RS00260	PF02491	SHS2 domain inserted in FTSA
SPH21_RS00270	PF02875	Mur ligase family, glutamate ligase domain
SPH21_RS00270	PF08245	Mur ligase middle domain
SPH21_RS00270	PF01225	Mur ligase family, catalytic domain
SPH21_RS00275	PF03033	Glycosyltransferase family 28 N-terminal domain
SPH21_RS00275	PF04101	Glycosyltransferase family 28 C-terminal domain
SPH21_RS00280	PF01098	Cell cycle protein
SPH21_RS00285	PF08245	Mur ligase middle domain
SPH21_RS00285	PF02875	Mur ligase family, glutamate ligase domain
SPH21_RS00290	PF10555	Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 
SPH21_RS00290	PF00953	Glycosyl transferase family 4
SPH21_RS00295	PF08245	Mur ligase middle domain
SPH21_RS00295	PF01225	Mur ligase family, catalytic domain
SPH21_RS00295	PF02875	Mur ligase family, glutamate ligase domain
SPH21_RS00300	PF00905	Penicillin binding protein transpeptidase domain
SPH21_RS00300	PF03717	Penicillin-binding Protein dimerisation domain
SPH21_RS00310	PF01795	MraW methylase family
SPH21_RS00315	PF02381	MraZ protein, putative antitoxin-like
SPH21_RS00325	PF00162	Phosphoglycerate kinase
SPH21_RS00335	PF02800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
SPH21_RS00335	PF00044	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
SPH21_RS00375	PF01018	GTP1/OBG
SPH21_RS00375	PF01926	50S ribosome-binding GTPase
SPH21_RS00405	PF06965	Na+/H+ antiporter 1
SPH21_RS00445	PF00593	TonB dependent receptor
SPH21_RS00445	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS00525	PF03372	Endonuclease/Exonuclease/phosphatase family
SPH21_RS00540	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS00540	PF00593	TonB dependent receptor
SPH21_RS00550	PF00083	Sugar (and other) transporter
SPH21_RS00560	PF00480	ROK family
SPH21_RS00560	PF01325	Iron dependent repressor, N-terminal DNA binding domain
SPH21_RS00595	PF12146	Serine aminopeptidase, S33
SPH21_RS00605	PF00135	Carboxylesterase family
SPH21_RS00625	PF00248	Aldo/keto reductase family
SPH21_RS00630	PF00248	Aldo/keto reductase family
SPH21_RS00640	PF07694	5TMR of 5TMR-LYT
SPH21_RS00640	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS00640	PF06580	Histidine kinase
SPH21_RS00645	PF00072	Response regulator receiver domain
SPH21_RS00645	PF04397	LytTr DNA-binding domain
SPH21_RS00665	PF02738	Molybdopterin-binding domain of aldehyde dehydrogenase
SPH21_RS00670	PF01799	[2Fe-2S] binding domain
SPH21_RS00670	PF00111	2Fe-2S iron-sulfur cluster binding domain
SPH21_RS00675	PF13478	XdhC Rossmann domain
SPH21_RS00675	PF02625	XdhC and CoxI family
SPH21_RS00680	PF04055	Radical SAM superfamily
SPH21_RS00680	PF06463	Molybdenum Cofactor Synthesis C
SPH21_RS00685	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS00685	PF00593	TonB dependent receptor
SPH21_RS00705	PF02391	MoaE protein
SPH21_RS00715	PF07786	Protein of unknown function (DUF1624)
SPH21_RS00715	PF04235	Protein of unknown function (DUF418)
SPH21_RS00740	PF07980	SusD family
SPH21_RS00745	PF00593	TonB dependent receptor
SPH21_RS00745	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS00775	PF17761	DUF1016 N-terminal domain
SPH21_RS00775	PF06250	YhcG PDDEXK nuclease domain
SPH21_RS00790	PF13817	IS66 C-terminal element
SPH21_RS00790	PF13007	Transposase C of IS166 homeodomain
SPH21_RS00790	PF13005	zinc-finger binding domain of transposase IS66 
SPH21_RS00790	PF03050	Transposase IS66 family 
SPH21_RS00860	PF01593	Flavin containing amine oxidoreductase
SPH21_RS00865	PF10518	TAT (twin-arginine translocation) pathway signal sequence
SPH21_RS00865	PF00149	Calcineurin-like phosphoesterase
SPH21_RS00875	PF00654	Voltage gated chloride channel
SPH21_RS00895	PF00593	TonB dependent receptor
SPH21_RS00895	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS00920	PF13460	NAD(P)H-binding 
SPH21_RS00950	PF07980	SusD family
SPH21_RS00955	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS00955	PF00593	TonB dependent receptor
SPH21_RS00970	PF00474	Sodium:solute symporter family
SPH21_RS00980	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS00990	PF03358	NADPH-dependent FMN reductase
SPH21_RS00995	PF00135	Carboxylesterase family
SPH21_RS01005	PF01235	Sodium:alanine symporter family
SPH21_RS01015	PF12867	DinB superfamily
SPH21_RS01020	PF01894	Uncharacterised protein family UPF0047
SPH21_RS01040	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS01040	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS01050	PF12833	Helix-turn-helix domain
SPH21_RS01050	PF02805	Metal binding domain of Ada
SPH21_RS01070	PF05661	Protein of unknown function (DUF808)
SPH21_RS01075	PF01022	Bacterial regulatory protein, arsR family
SPH21_RS01095	PF01545	Cation efflux family
SPH21_RS01100	PF00873	AcrB/AcrD/AcrF family
SPH21_RS01110	PF00403	Heavy-metal-associated domain
SPH21_RS01130	PF01758	Sodium Bile acid symporter family
SPH21_RS01135	PF01451	Low molecular weight phosphotyrosine protein phosphatase
SPH21_RS01140	PF00583	Acetyltransferase (GNAT) family
SPH21_RS01265	PF04397	LytTr DNA-binding domain
SPH21_RS01265	PF00072	Response regulator receiver domain
SPH21_RS01270	PF06580	Histidine kinase
SPH21_RS01270	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS01270	PF07694	5TMR of 5TMR-LYT
SPH21_RS01280	PF13091	PLD-like domain
SPH21_RS01280	PF13087	AAA domain
SPH21_RS01295	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS01295	PF00593	TonB dependent receptor
SPH21_RS01305	PF08534	Redoxin
SPH21_RS01365	PF00561	alpha/beta hydrolase fold
SPH21_RS01370	PF00403	Heavy-metal-associated domain
SPH21_RS01375	PF00394	Multicopper oxidase
SPH21_RS01375	PF07731	Multicopper oxidase
SPH21_RS01375	PF07732	Multicopper oxidase
SPH21_RS01390	PF13533	Biotin-lipoyl like
SPH21_RS01405	PF00873	AcrB/AcrD/AcrF family
SPH21_RS01410	PF00873	AcrB/AcrD/AcrF family
SPH21_RS01440	PF01494	FAD binding domain
SPH21_RS01465	PF01638	HxlR-like helix-turn-helix
SPH21_RS01470	PF00916	Sulfate permease family
SPH21_RS01470	PF01740	STAS domain
SPH21_RS01480	PF13495	Phage integrase, N-terminal SAM-like domain
SPH21_RS01480	PF00589	Phage integrase family
SPH21_RS01510	PF02899	Phage integrase, N-terminal SAM-like domain
SPH21_RS01510	PF00589	Phage integrase family
SPH21_RS01530	PF02446	4-alpha-glucanotransferase
SPH21_RS01535	PF00128	Alpha amylase, catalytic domain
SPH21_RS01535	PF11941	Domain of unknown function (DUF3459)
SPH21_RS01540	PF00128	Alpha amylase, catalytic domain
SPH21_RS01540	PF02922	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
SPH21_RS01550	PF02548	Ketopantoate hydroxymethyltransferase
SPH21_RS01555	PF02742	Iron dependent repressor, metal binding and dimerisation domain
SPH21_RS01555	PF18357	Diphteria toxin repressor SH3 domain
SPH21_RS01555	PF01325	Iron dependent repressor, N-terminal DNA binding domain
SPH21_RS01560	PF01668	SmpB protein
SPH21_RS01575	PF17764	3′ DNA-binding domain (3′BD)
SPH21_RS01575	PF18074	Primosomal protein N C-terminal domain
SPH21_RS01575	PF00271	Helicase conserved C-terminal domain
SPH21_RS01575	PF18319	PriA DNA helicase Cys-rich region (CRR) domain
SPH21_RS01575	PF04851	Type III restriction enzyme, res subunit
SPH21_RS01580	PF04241	Protein of unknown function (DUF423)
SPH21_RS01590	PF00814	Glycoprotease family
SPH21_RS01595	PF00825	Ribonuclease P
SPH21_RS01600	PF00468	Ribosomal protein L34
SPH21_RS01605	PF01741	Large-conductance mechanosensitive channel, MscL
SPH21_RS01610	PF00309	Sigma-54 factor, Activator interacting domain (AID) 
SPH21_RS01610	PF04552	Sigma-54, DNA binding domain
SPH21_RS01610	PF04963	Sigma-54 factor, core binding domain
SPH21_RS01615	PF00795	Carbon-nitrogen hydrolase
SPH21_RS01615	PF02540	NAD synthase
SPH21_RS01620	PF04371	Porphyromonas-type peptidyl-arginine deiminase
SPH21_RS01630	PF00988	Carbamoyl-phosphate synthase small chain, CPSase domain
SPH21_RS01630	PF00117	Glutamine amidotransferase class-I
SPH21_RS01635	PF03952	Enolase, N-terminal domain
SPH21_RS01635	PF00113	Enolase, C-terminal TIM barrel domain
SPH21_RS01650	PF03061	Thioesterase superfamily
SPH21_RS01655	PF03477	ATP cone domain
SPH21_RS01655	PF02867	Ribonucleotide reductase, barrel domain
SPH21_RS01655	PF00317	Ribonucleotide reductase, all-alpha domain
SPH21_RS01665	PF01624	MutS domain I
SPH21_RS01665	PF05188	MutS domain II
SPH21_RS01665	PF05192	MutS domain III
SPH21_RS01665	PF05190	MutS family domain IV
SPH21_RS01665	PF00488	MutS domain V
SPH21_RS01670	PF01609	Transposase DDE domain
SPH21_RS01680	PF02590	Predicted SPOUT methyltransferase
SPH21_RS01690	PF00160	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
SPH21_RS01700	PF01048	Phosphorylase superfamily
SPH21_RS01705	PF02606	Tetraacyldisaccharide-1-P 4'-kinase
SPH21_RS01710	PF00171	Aldehyde dehydrogenase family
SPH21_RS01760	PF01965	DJ-1/PfpI family
SPH21_RS01780	PF07690	Major Facilitator Superfamily
SPH21_RS01785	PF01926	50S ribosome-binding GTPase
SPH21_RS01785	PF07650	KH domain
SPH21_RS01805	PF03971	Monomeric isocitrate dehydrogenase
SPH21_RS01820	PF14714	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
SPH21_RS01820	PF01926	50S ribosome-binding GTPase
SPH21_RS01825	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS01830	PF01182	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
SPH21_RS01835	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS01855	PF03572	Peptidase family S41
SPH21_RS01855	PF13180	PDZ domain
SPH21_RS01870	PF02607	B12 binding domain
SPH21_RS01870	PF02310	B12 binding domain
SPH21_RS01870	PF02965	Vitamin B12 dependent methionine synthase, activation domain
SPH21_RS01870	PF00809	Pterin binding enzyme
SPH21_RS01870	PF02574	Homocysteine S-methyltransferase
SPH21_RS01880	PF02219	Methylenetetrahydrofolate reductase
SPH21_RS01890	PF02566	OsmC-like protein
SPH21_RS01895	PF00593	TonB dependent receptor
SPH21_RS01895	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS01905	PF00085	Thioredoxin
SPH21_RS01915	PF00593	TonB dependent receptor
SPH21_RS01915	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS01920	PF14322	Starch-binding associating with outer membrane
SPH21_RS01920	PF07980	SusD family
SPH21_RS01925	PF00884	Sulfatase
SPH21_RS01930	PF00085	Thioredoxin
SPH21_RS01940	PF03601	Conserved hypothetical protein 698
SPH21_RS01945	PF03781	Sulfatase-modifying factor enzyme 1
SPH21_RS01950	PF02463	RecF/RecN/SMC N terminal domain
SPH21_RS01965	PF13635	Domain of unknown function (DUF4143)
SPH21_RS01965	PF13173	AAA domain
SPH21_RS02010	PF10431	C-terminal, D2-small domain, of ClpB protein 
SPH21_RS02010	PF17871	AAA lid domain
SPH21_RS02010	PF00004	ATPase family associated with various cellular activities (AAA)
SPH21_RS02010	PF02861	Clp amino terminal domain, pathogenicity island component
SPH21_RS02010	PF07724	AAA domain (Cdc48 subfamily)
SPH21_RS02015	PF12848	ABC transporter
SPH21_RS02015	PF00005	ABC transporter
SPH21_RS02035	PF01548	Transposase
SPH21_RS02035	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS02040	PF00578	AhpC/TSA family
SPH21_RS02045	PF08402	TOBE domain
SPH21_RS02045	PF00005	ABC transporter
SPH21_RS02070	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
SPH21_RS02070	PF00529	HlyD membrane-fusion protein of T1SS
SPH21_RS02075	PF00873	AcrB/AcrD/AcrF family
SPH21_RS02080	PF02321	Outer membrane efflux protein
SPH21_RS02085	PF10502	Signal peptidase, peptidase S26 
SPH21_RS02090	PF05173	Dihydrodipicolinate reductase, C-terminus
SPH21_RS02090	PF01113	Dihydrodipicolinate reductase, N-terminus
SPH21_RS02100	PF17762	HTH domain found in ParB protein
SPH21_RS02100	PF02195	ParB-like nuclease domain
SPH21_RS02105	PF13614	AAA domain
SPH21_RS02115	PF08220	DeoR-like helix-turn-helix domain
SPH21_RS02115	PF00455	DeoR C terminal sensor domain
SPH21_RS02120	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02120	PF00593	TonB dependent receptor
SPH21_RS02130	PF07690	Major Facilitator Superfamily
SPH21_RS02135	PF02826	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
SPH21_RS02135	PF00389	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
SPH21_RS02140	PF00370	FGGY family of carbohydrate kinases, N-terminal domain
SPH21_RS02140	PF02782	FGGY family of carbohydrate kinases, C-terminal domain
SPH21_RS02145	PF02782	FGGY family of carbohydrate kinases, C-terminal domain
SPH21_RS02145	PF00370	FGGY family of carbohydrate kinases, N-terminal domain
SPH21_RS02150	PF00300	Histidine phosphatase superfamily (branch 1)
SPH21_RS02160	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS02180	PF17389	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
SPH21_RS02180	PF08531	Alpha-L-rhamnosidase N-terminal domain
SPH21_RS02180	PF17390	Bacterial alpha-L-rhamnosidase C-terminal domain
SPH21_RS02180	PF05592	Bacterial alpha-L-rhamnosidase concanavalin-like domain
SPH21_RS02190	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS02205	PF01761	3-dehydroquinate synthase
SPH21_RS02210	PF01040	UbiA prenyltransferase family
SPH21_RS02235	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS02235	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS02260	PF07980	SusD family
SPH21_RS02260	PF14322	Starch-binding associating with outer membrane
SPH21_RS02265	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02265	PF00593	TonB dependent receptor
SPH21_RS02280	PF17389	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
SPH21_RS02280	PF17390	Bacterial alpha-L-rhamnosidase C-terminal domain
SPH21_RS02280	PF05592	Bacterial alpha-L-rhamnosidase concanavalin-like domain
SPH21_RS02280	PF08531	Alpha-L-rhamnosidase N-terminal domain
SPH21_RS02290	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS02290	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS02300	PF05336	L-rhamnose mutarotase
SPH21_RS02310	PF13472	GDSL-like Lipase/Acylhydrolase family
SPH21_RS02350	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02350	PF00593	TonB dependent receptor
SPH21_RS02365	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02365	PF00593	TonB dependent receptor
SPH21_RS02370	PF07980	SusD family
SPH21_RS02370	PF14322	Starch-binding associating with outer membrane
SPH21_RS02375	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02375	PF00593	TonB dependent receptor
SPH21_RS02380	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS02380	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS02380	PF00703	Glycosyl hydrolases family 2
SPH21_RS02380	PF16353	Domain of unknown function(DUF4981)
SPH21_RS02380	PF02929	Beta galactosidase small chain
SPH21_RS02390	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS02390	PF01548	Transposase
SPH21_RS02405	PF05448	Acetyl xylan esterase (AXE1)
SPH21_RS02425	PF00593	TonB dependent receptor
SPH21_RS02425	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02430	PF14322	Starch-binding associating with outer membrane
SPH21_RS02430	PF07980	SusD family
SPH21_RS02465	PF00593	TonB dependent receptor
SPH21_RS02465	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02480	PF00593	TonB dependent receptor
SPH21_RS02480	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02505	PF01609	Transposase DDE domain
SPH21_RS02525	PF00072	Response regulator receiver domain
SPH21_RS02525	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS02530	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS02530	PF18698	Histidine kinase sensor domain
SPH21_RS02530	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS02530	PF00672	HAMP domain
SPH21_RS02530	PF00989	PAS fold
SPH21_RS02540	PF01261	Xylose isomerase-like TIM barrel
SPH21_RS02545	PF00596	Class II Aldolase and Adducin N-terminal domain
SPH21_RS02550	PF06379	L-rhamnose-proton symport protein (RhaT)
SPH21_RS02565	PF05193	Peptidase M16 inactive domain
SPH21_RS02565	PF00675	Insulinase (Peptidase family M16)
SPH21_RS02580	PF00176	SNF2 family N-terminal domain
SPH21_RS02580	PF12419	SNF2 Helicase protein 
SPH21_RS02580	PF00271	Helicase conserved C-terminal domain
SPH21_RS02595	PF03061	Thioesterase superfamily
SPH21_RS02600	PF01112	Asparaginase
SPH21_RS02605	PF01037	Lrp/AsnC ligand binding domain
SPH21_RS02610	PF00892	EamA-like transporter family
SPH21_RS02625	PF13089	Polyphosphate kinase N-terminal domain
SPH21_RS02625	PF17941	Polyphosphate kinase C-terminal domain 1
SPH21_RS02625	PF13090	Polyphosphate kinase C-terminal domain 2
SPH21_RS02625	PF02503	Polyphosphate kinase middle domain
SPH21_RS02650	PF00005	ABC transporter
SPH21_RS02650	PF00664	ABC transporter transmembrane region
SPH21_RS02655	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS02655	PF00155	Aminotransferase class I and II
SPH21_RS02660	PF02627	Carboxymuconolactone decarboxylase family
SPH21_RS02680	PF00583	Acetyltransferase (GNAT) family
SPH21_RS02690	PF13603	Leucyl-tRNA synthetase, Domain 2
SPH21_RS02690	PF00133	tRNA synthetases class I (I, L, M and V)
SPH21_RS02690	PF08264	Anticodon-binding domain of tRNA
SPH21_RS02695	PF18075	FtsX extracellular domain
SPH21_RS02705	PF02673	Bacitracin resistance protein BacA
SPH21_RS02710	PF01509	TruB family pseudouridylate synthase (N terminal domain)
SPH21_RS02715	PF06574	FAD synthetase
SPH21_RS02715	PF01687	Riboflavin kinase
SPH21_RS02725	PF04264	YceI-like domain
SPH21_RS02730	PF02566	OsmC-like protein
SPH21_RS02735	PF01053	Cys/Met metabolism PLP-dependent enzyme
SPH21_RS02740	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
SPH21_RS02740	PF14824	Sirohaem biosynthesis protein central
SPH21_RS02740	PF10414	Sirohaem synthase dimerisation region
SPH21_RS02745	PF02082	Transcriptional regulator
SPH21_RS02750	PF17760	UvrA interaction domain
SPH21_RS02750	PF17755	UvrA DNA-binding domain
SPH21_RS02755	PF08281	Sigma-70, region 4
SPH21_RS02755	PF04542	Sigma-70 region 2 
SPH21_RS02765	PF00781	Diacylglycerol kinase catalytic domain
SPH21_RS02765	PF02142	MGS-like domain
SPH21_RS02790	PF00926	3,4-dihydroxy-2-butanone 4-phosphate synthase
SPH21_RS02790	PF00925	GTP cyclohydrolase II
SPH21_RS02800	PF00814	Glycoprotease family
SPH21_RS02810	PF00154	recA bacterial DNA recombination protein
SPH21_RS02815	PF10576	Iron-sulfur binding domain of endonuclease III
SPH21_RS02815	PF00730	HhH-GPD superfamily base excision DNA repair protein
SPH21_RS02815	PF00633	Helix-hairpin-helix motif
SPH21_RS02820	PF00082	Subtilase family
SPH21_RS02850	PF17125	N-terminal domain of 16S rRNA methyltransferase RsmF
SPH21_RS02850	PF13636	RNA-binding PUA-like domain of methyltransferase RsmF
SPH21_RS02850	PF01189	16S rRNA methyltransferase RsmB/F
SPH21_RS02855	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS02860	PF02614	Glucuronate isomerase
SPH21_RS02865	PF03786	D-mannonate dehydratase (UxuA)
SPH21_RS02870	PF00106	short chain dehydrogenase
SPH21_RS02875	PF00294	pfkB family carbohydrate kinase
SPH21_RS02880	PF01081	KDPG and KHG aldolase
SPH21_RS02885	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS02885	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS02895	PF07980	SusD family
SPH21_RS02895	PF14322	Starch-binding associating with outer membrane
SPH21_RS02900	PF00593	TonB dependent receptor
SPH21_RS02900	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02905	PF00072	Response regulator receiver domain
SPH21_RS02905	PF12833	Helix-turn-helix domain
SPH21_RS02905	PF07494	Two component regulator propeller
SPH21_RS02905	PF07495	Y_Y_Y domain
SPH21_RS02905	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS02905	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS02910	PF12833	Helix-turn-helix domain
SPH21_RS02910	PF07495	Y_Y_Y domain
SPH21_RS02910	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS02910	PF00072	Response regulator receiver domain
SPH21_RS02910	PF07494	Two component regulator propeller
SPH21_RS02910	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS02935	PF00664	ABC transporter transmembrane region
SPH21_RS02935	PF00005	ABC transporter
SPH21_RS02955	PF04616	Glycosyl hydrolases family 43
SPH21_RS02960	PF01263	Aldose 1-epimerase
SPH21_RS02965	PF18565	Glycoside hydrolase family 2 C-terminal domain 5
SPH21_RS02965	PF16355	Domain of unknown function (DUF4982)
SPH21_RS02965	PF00703	Glycosyl hydrolases family 2
SPH21_RS02965	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS02965	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS02990	PF07980	SusD family
SPH21_RS02990	PF14322	Starch-binding associating with outer membrane
SPH21_RS02995	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS02995	PF00593	TonB dependent receptor
SPH21_RS03010	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS03025	PF07683	Cobalamin synthesis protein cobW C-terminal domain
SPH21_RS03025	PF02492	CobW/HypB/UreG, nucleotide-binding domain
SPH21_RS03035	PF02782	FGGY family of carbohydrate kinases, C-terminal domain
SPH21_RS03040	PF07690	Major Facilitator Superfamily
SPH21_RS03045	PF07882	L-fucose isomerase, second N-terminal domain
SPH21_RS03045	PF07881	L-fucose isomerase, first N-terminal domain
SPH21_RS03045	PF02952	L-fucose isomerase, C-terminal domain
SPH21_RS03070	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS03070	PF00593	TonB dependent receptor
SPH21_RS03085	PF01557	Fumarylacetoacetate (FAA) hydrolase family
SPH21_RS03095	PF08666	SAF domain
SPH21_RS03095	PF04295	D-galactarate dehydratase / Altronate hydrolase, C terminus
SPH21_RS03100	PF05336	L-rhamnose mutarotase
SPH21_RS03105	PF07690	Major Facilitator Superfamily
SPH21_RS03110	PF12833	Helix-turn-helix domain
SPH21_RS03110	PF01497	Periplasmic binding protein
SPH21_RS03125	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS03125	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS03135	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS03150	PF00593	TonB dependent receptor
SPH21_RS03150	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS03155	PF00593	TonB dependent receptor
SPH21_RS03155	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS03170	PF01548	Transposase
SPH21_RS03170	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS03175	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS03175	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS03180	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS03180	PF00593	TonB dependent receptor
SPH21_RS03195	PF12034	Domain of unknown function (DUF3520)
SPH21_RS03195	PF12450	von Willebrand factor 
SPH21_RS03195	PF00092	von Willebrand factor type A domain
SPH21_RS03205	PF00903	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
SPH21_RS03210	PF02838	Glycosyl hydrolase family 20, domain 2
SPH21_RS03210	PF07691	PA14 domain
SPH21_RS03210	PF00728	Glycosyl hydrolase family 20, catalytic domain
SPH21_RS03225	PF00282	Pyridoxal-dependent decarboxylase conserved domain
SPH21_RS03230	PF01037	Lrp/AsnC ligand binding domain
SPH21_RS03245	PF04397	LytTr DNA-binding domain
SPH21_RS03245	PF00072	Response regulator receiver domain
SPH21_RS03250	PF07694	5TMR of 5TMR-LYT
SPH21_RS03250	PF06580	Histidine kinase
SPH21_RS03250	PF13492	GAF domain
SPH21_RS03250	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS03255	PF07691	PA14 domain
SPH21_RS03255	PF02838	Glycosyl hydrolase family 20, domain 2
SPH21_RS03255	PF00728	Glycosyl hydrolase family 20, catalytic domain
SPH21_RS03260	PF07691	PA14 domain
SPH21_RS03260	PF02838	Glycosyl hydrolase family 20, domain 2
SPH21_RS03260	PF00728	Glycosyl hydrolase family 20, catalytic domain
SPH21_RS03270	PF02589	LUD domain
SPH21_RS03275	PF13183	4Fe-4S dicluster domain
SPH21_RS03275	PF11870	Domain of unknown function (DUF3390)
SPH21_RS03275	PF02589	LUD domain
SPH21_RS03280	PF02754	Cysteine-rich domain
SPH21_RS03285	PF04185	Phosphoesterase family
SPH21_RS03285	PF05506	Domain of unknown function (DUF756)
SPH21_RS03290	PF00171	Aldehyde dehydrogenase family
SPH21_RS03295	PF07722	Peptidase C26
SPH21_RS03300	PF00465	Iron-containing alcohol dehydrogenase 
SPH21_RS03305	PF00120	Glutamine synthetase, catalytic domain
SPH21_RS03310	PF13520	Amino acid permease
SPH21_RS03320	PF02021	Uncharacterised protein family UPF0102
SPH21_RS03325	PF01807	CHC2 zinc finger
SPH21_RS03325	PF08275	DNA primase catalytic core, N-terminal domain
SPH21_RS03325	PF10410	DnaB-helicase binding domain of primase
SPH21_RS03330	PF00924	Mechanosensitive ion channel
SPH21_RS03335	PF07687	Peptidase dimerisation domain
SPH21_RS03335	PF01546	Peptidase family M20/M25/M40
SPH21_RS03345	PF07517	SecA DEAD-like domain
SPH21_RS03345	PF01043	SecA preprotein cross-linking domain
SPH21_RS03345	PF07516	SecA Wing and Scaffold domain
SPH21_RS03355	PF07995	Glucose / Sorbosone dehydrogenase
SPH21_RS03360	PF00342	Phosphoglucose isomerase
SPH21_RS03370	PF00472	RF-1 domain
SPH21_RS03370	PF03462	PCRF domain
SPH21_RS03390	PF01609	Transposase DDE domain
SPH21_RS03430	PF04397	LytTr DNA-binding domain
SPH21_RS03430	PF00072	Response regulator receiver domain
SPH21_RS03440	PF14028	Lantibiotic biosynthesis dehydratase C-term
SPH21_RS03440	PF04738	Lantibiotic dehydratase, N terminus
SPH21_RS03450	PF00005	ABC transporter
SPH21_RS03450	PF03412	Peptidase C39 family
SPH21_RS03450	PF00664	ABC transporter transmembrane region
SPH21_RS03465	PF03099	Biotin/lipoate A/B protein ligase family
SPH21_RS03475	PF03313	Serine dehydratase alpha chain
SPH21_RS03475	PF03315	Serine dehydratase beta chain
SPH21_RS03515	PF07726	ATPase family associated with various cellular activities (AAA)
SPH21_RS03515	PF17863	AAA lid domain
SPH21_RS03530	PF00005	ABC transporter
SPH21_RS03530	PF12399	Branched-chain amino acid ATP-binding cassette transporter
SPH21_RS03535	PF02272	DHHA1 domain
SPH21_RS03535	PF10141	Single-strand DNA-specific exonuclease, C terminal domain
SPH21_RS03535	PF17768	RecJ OB domain
SPH21_RS03535	PF01368	DHH family
SPH21_RS03540	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS03545	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS03545	PF00072	Response regulator receiver domain
SPH21_RS03550	PF07730	Histidine kinase
SPH21_RS03550	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS03560	PF04851	Type III restriction enzyme, res subunit
SPH21_RS03560	PF00271	Helicase conserved C-terminal domain
SPH21_RS03560	PF02151	UvrB/uvrC motif
SPH21_RS03560	PF12344	Ultra-violet resistance protein B
SPH21_RS03560	PF17757	UvrB interaction domain
SPH21_RS03570	PF13419	Haloacid dehalogenase-like hydrolase
SPH21_RS03575	PF00480	ROK family
SPH21_RS03580	PF07470	Glycosyl Hydrolase Family 88
SPH21_RS03590	PF16153	Domain of unknown function (DUF4861)
SPH21_RS03595	PF04962	KduI/IolB family
SPH21_RS03605	PF07470	Glycosyl Hydrolase Family 88
SPH21_RS03610	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS03625	PF04011	LemA family
SPH21_RS03635	PF04536	TPM domain
SPH21_RS03645	PF07859	alpha/beta hydrolase fold
SPH21_RS03645	PF13472	GDSL-like Lipase/Acylhydrolase family
SPH21_RS03655	PF16363	GDP-mannose 4,6 dehydratase
SPH21_RS03665	PF00578	AhpC/TSA family
SPH21_RS03670	PF01063	Amino-transferase class IV
SPH21_RS03685	PF00919	Uncharacterized protein family UPF0004
SPH21_RS03685	PF01938	TRAM domain
SPH21_RS03685	PF04055	Radical SAM superfamily
SPH21_RS03690	PF02954	Bacterial regulatory protein, Fis family
SPH21_RS03690	PF00158	Sigma-54 interaction domain
SPH21_RS03690	PF00072	Response regulator receiver domain
SPH21_RS03710	PF00166	Chaperonin 10 Kd subunit
SPH21_RS03715	PF00118	TCP-1/cpn60 chaperonin family
SPH21_RS03735	PF01594	AI-2E family transporter
SPH21_RS03740	PF00378	Enoyl-CoA hydratase/isomerase
SPH21_RS03750	PF03734	L,D-transpeptidase catalytic domain
SPH21_RS03750	PF01471	Putative peptidoglycan binding domain
SPH21_RS03760	PF04468	PSP1 C-terminal conserved region
SPH21_RS03765	PF09115	DNA polymerase III, delta subunit, C terminal
SPH21_RS03770	PF03652	Holliday junction resolvase
SPH21_RS03775	PF01596	O-methyltransferase
SPH21_RS03780	PF05257	CHAP domain
SPH21_RS03780	PF01476	LysM domain
SPH21_RS03785	PF10135	Rod binding protein
SPH21_RS03785	PF01832	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
SPH21_RS03800	PF01510	N-acetylmuramoyl-L-alanine amidase
SPH21_RS03805	PF00749	tRNA synthetases class I (E and Q), catalytic domain
SPH21_RS03805	PF03950	tRNA synthetases class I (E and Q), anti-codon binding domain
SPH21_RS03810	PF00313	'Cold-shock' DNA-binding domain
SPH21_RS03815	PF00271	Helicase conserved C-terminal domain
SPH21_RS03815	PF00270	DEAD/DEAH box helicase
SPH21_RS03820	PF01435	Peptidase family M48
SPH21_RS03825	PF01979	Amidohydrolase family
SPH21_RS03830	PF01979	Amidohydrolase family
SPH21_RS03835	PF00903	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
SPH21_RS03845	PF00210	Ferritin-like domain
SPH21_RS03855	PF00226	DnaJ domain
SPH21_RS03855	PF01556	DnaJ C terminal domain
SPH21_RS03860	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS03870	PF00005	ABC transporter
SPH21_RS03875	PF01915	Glycosyl hydrolase family 3 C-terminal domain
SPH21_RS03875	PF00933	Glycosyl hydrolase family 3 N terminal domain
SPH21_RS03880	PF00933	Glycosyl hydrolase family 3 N terminal domain
SPH21_RS03880	PF01915	Glycosyl hydrolase family 3 C-terminal domain
SPH21_RS03905	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS03905	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS03930	PF01757	Acyltransferase family
SPH21_RS03945	PF00593	TonB dependent receptor
SPH21_RS03945	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS03970	PF00593	TonB dependent receptor
SPH21_RS03970	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS03975	PF07980	SusD family
SPH21_RS03975	PF14322	Starch-binding associating with outer membrane
SPH21_RS04000	PF04069	Substrate binding domain of ABC-type glycine betaine transport system
SPH21_RS04005	PF00528	Binding-protein-dependent transport system inner membrane component
SPH21_RS04010	PF00571	CBS domain
SPH21_RS04010	PF00005	ABC transporter
SPH21_RS04055	PF12833	Helix-turn-helix domain
SPH21_RS04055	PF02311	AraC-like ligand binding domain
SPH21_RS04080	PF01494	FAD binding domain
SPH21_RS04085	PF01638	HxlR-like helix-turn-helix
SPH21_RS04090	PF10996	Beta-Casp domain
SPH21_RS04090	PF07521	Zn-dependent metallo-hydrolase RNA specificity domain
SPH21_RS04090	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS04110	PF00884	Sulfatase
SPH21_RS04125	PF07075	Protein of unknown function (DUF1343)
SPH21_RS04135	PF00593	TonB dependent receptor
SPH21_RS04135	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04150	PF02687	FtsX-like permease family
SPH21_RS04150	PF12704	MacB-like periplasmic core domain
SPH21_RS04185	PF01695	IstB-like ATP binding protein
SPH21_RS04190	PF00665	Integrase core domain
SPH21_RS04200	PF04397	LytTr DNA-binding domain
SPH21_RS04200	PF00072	Response regulator receiver domain
SPH21_RS04210	PF00665	Integrase core domain
SPH21_RS04215	PF01695	IstB-like ATP binding protein
SPH21_RS04255	PF01872	RibD C-terminal domain
SPH21_RS04295	PF00072	Response regulator receiver domain
SPH21_RS04295	PF04397	LytTr DNA-binding domain
SPH21_RS04315	PF12833	Helix-turn-helix domain
SPH21_RS04375	PF13533	Biotin-lipoyl like
SPH21_RS04380	PF07690	Major Facilitator Superfamily
SPH21_RS04395	PF00873	AcrB/AcrD/AcrF family
SPH21_RS04430	PF00145	C-5 cytosine-specific DNA methylase
SPH21_RS04435	PF02678	Pirin
SPH21_RS04435	PF05726	Pirin C-terminal cupin domain
SPH21_RS04450	PF01872	RibD C-terminal domain
SPH21_RS04455	PF00561	alpha/beta hydrolase fold
SPH21_RS04465	PF00664	ABC transporter transmembrane region
SPH21_RS04465	PF00005	ABC transporter
SPH21_RS04475	PF00106	short chain dehydrogenase
SPH21_RS04500	PF12833	Helix-turn-helix domain
SPH21_RS04505	PF00903	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
SPH21_RS04520	PF00106	short chain dehydrogenase
SPH21_RS04540	PF00593	TonB dependent receptor
SPH21_RS04540	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04545	PF01810	LysE type translocator
SPH21_RS04550	PF07883	Cupin domain
SPH21_RS04550	PF12833	Helix-turn-helix domain
SPH21_RS04560	PF14322	Starch-binding associating with outer membrane
SPH21_RS04560	PF07980	SusD family
SPH21_RS04565	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04565	PF00593	TonB dependent receptor
SPH21_RS04570	PF04041	beta-1,4-mannooligosaccharide phosphorylase
SPH21_RS04585	PF02156	Glycosyl hydrolase family 26
SPH21_RS04615	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04615	PF00593	TonB dependent receptor
SPH21_RS04620	PF07980	SusD family
SPH21_RS04625	PF00884	Sulfatase
SPH21_RS04640	PF00248	Aldo/keto reductase family
SPH21_RS04655	PF03060	Nitronate monooxygenase
SPH21_RS04665	PF01609	Transposase DDE domain
SPH21_RS04665	PF13808	DDE_Tnp_1-associated
SPH21_RS04675	PF07690	Major Facilitator Superfamily
SPH21_RS04680	PF04072	Leucine carboxyl methyltransferase
SPH21_RS04690	PF00884	Sulfatase
SPH21_RS04715	PF08818	Domain of unknown function (DU1801)
SPH21_RS04725	PF03852	DNA mismatch endonuclease Vsr
SPH21_RS04725	PF04480	Protein of unknown function (DUF559)
SPH21_RS04740	PF02743	Cache domain
SPH21_RS04740	PF00672	HAMP domain
SPH21_RS04740	PF06580	Histidine kinase
SPH21_RS04740	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS04745	PF00072	Response regulator receiver domain
SPH21_RS04745	PF04397	LytTr DNA-binding domain
SPH21_RS04750	PF00245	Alkaline phosphatase
SPH21_RS04760	PF00593	TonB dependent receptor
SPH21_RS04760	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04770	PF04539	Sigma-70 region 3
SPH21_RS04770	PF04542	Sigma-70 region 2 
SPH21_RS04770	PF04545	Sigma-70, region 4
SPH21_RS04775	PF01638	HxlR-like helix-turn-helix
SPH21_RS04780	PF02525	Flavodoxin-like fold
SPH21_RS04785	PF00005	ABC transporter
SPH21_RS04785	PF16326	ABC transporter C-terminal domain
SPH21_RS04785	PF12848	ABC transporter
SPH21_RS04790	PF00722	Glycosyl hydrolases family 16
SPH21_RS04805	PF00474	Sodium:solute symporter family
SPH21_RS04810	PF07005	Sugar-binding N-terminal domain
SPH21_RS04810	PF17042	Nucleotide-binding C-terminal domain
SPH21_RS04815	PF04166	Pyridoxal phosphate biosynthetic protein PdxA
SPH21_RS04820	PF00701	Dihydrodipicolinate synthetase family
SPH21_RS04825	PF00465	Iron-containing alcohol dehydrogenase 
SPH21_RS04830	PF12833	Helix-turn-helix domain
SPH21_RS04830	PF07883	Cupin domain
SPH21_RS04845	PF01266	FAD dependent oxidoreductase
SPH21_RS04850	PF05544	Proline racemase
SPH21_RS04855	PF00171	Aldehyde dehydrogenase family
SPH21_RS04860	PF00701	Dihydrodipicolinate synthetase family
SPH21_RS04865	PF02311	AraC-like ligand binding domain
SPH21_RS04865	PF12833	Helix-turn-helix domain
SPH21_RS04870	PF00557	Metallopeptidase family M24
SPH21_RS04870	PF05195	Aminopeptidase P, N-terminal domain
SPH21_RS04875	PF00326	Prolyl oligopeptidase family
SPH21_RS04875	PF00930	Dipeptidyl peptidase IV (DPP IV) N-terminal region
SPH21_RS04895	PF00593	TonB dependent receptor
SPH21_RS04895	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04910	PF00593	TonB dependent receptor
SPH21_RS04910	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04915	PF07980	SusD family
SPH21_RS04915	PF14322	Starch-binding associating with outer membrane
SPH21_RS04930	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04930	PF00593	TonB dependent receptor
SPH21_RS04955	PF00593	TonB dependent receptor
SPH21_RS04955	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04970	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04970	PF00593	TonB dependent receptor
SPH21_RS04975	PF00854	POT family
SPH21_RS04985	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS04985	PF00593	TonB dependent receptor
SPH21_RS05000	PF00326	Prolyl oligopeptidase family
SPH21_RS05000	PF00930	Dipeptidyl peptidase IV (DPP IV) N-terminal region
SPH21_RS05005	PF13520	Amino acid permease
SPH21_RS05015	PF00732	GMC oxidoreductase
SPH21_RS05015	PF05199	GMC oxidoreductase
SPH21_RS05020	PF10566	Glycoside hydrolase 97  
SPH21_RS05020	PF14508	Glycosyl-hydrolase 97 N-terminal
SPH21_RS05020	PF14509	Glycosyl-hydrolase 97 C-terminal, oligomerisation
SPH21_RS05025	PF01263	Aldose 1-epimerase
SPH21_RS05035	PF06964	Alpha-L-arabinofuranosidase C-terminal domain
SPH21_RS05035	PF02018	Carbohydrate binding domain
SPH21_RS05040	PF06964	Alpha-L-arabinofuranosidase C-terminal domain
SPH21_RS05055	PF02782	FGGY family of carbohydrate kinases, C-terminal domain
SPH21_RS05060	PF00596	Class II Aldolase and Adducin N-terminal domain
SPH21_RS05065	PF11762	L-arabinose isomerase C-terminal domain
SPH21_RS05065	PF02610	L-arabinose isomerase
SPH21_RS05070	PF00474	Sodium:solute symporter family
SPH21_RS05080	PF00764	Arginosuccinate synthase
SPH21_RS05085	PF02774	Semialdehyde dehydrogenase, dimerisation domain
SPH21_RS05085	PF01118	Semialdehyde dehydrogenase, NAD binding domain
SPH21_RS05095	PF00202	Aminotransferase class-III
SPH21_RS05100	PF02729	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
SPH21_RS05100	PF00185	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
SPH21_RS05105	PF00696	Amino acid kinase family
SPH21_RS05120	PF00206	Lyase
SPH21_RS05125	PF00696	Amino acid kinase family
SPH21_RS05135	PF04055	Radical SAM superfamily
SPH21_RS05135	PF06969	HemN C-terminal domain
SPH21_RS05140	PF00106	short chain dehydrogenase
SPH21_RS05150	PF01370	NAD dependent epimerase/dehydratase family
SPH21_RS05155	PF16363	GDP-mannose 4,6 dehydratase
SPH21_RS05160	PF16363	GDP-mannose 4,6 dehydratase
SPH21_RS05185	PF02589	LUD domain
SPH21_RS05190	PF00004	ATPase family associated with various cellular activities (AAA)
SPH21_RS05190	PF01434	Peptidase family M41
SPH21_RS05190	PF06480	FtsH Extracellular
SPH21_RS05190	PF17862	AAA+ lid domain
SPH21_RS05200	PF02237	Biotin protein ligase C terminal domain
SPH21_RS05200	PF08279	HTH domain
SPH21_RS05200	PF03099	Biotin/lipoate A/B protein ligase family
SPH21_RS05210	PF02683	Cytochrome C biogenesis protein transmembrane region
SPH21_RS05210	PF13098	Thioredoxin-like domain
SPH21_RS05210	PF11412	Disulphide bond corrector protein DsbC
SPH21_RS05215	PF00365	Phosphofructokinase
SPH21_RS05220	PF03466	LysR substrate binding domain
SPH21_RS05220	PF00126	Bacterial regulatory helix-turn-helix protein, lysR family
SPH21_RS05225	PF01625	Peptide methionine sulfoxide reductase
SPH21_RS05230	PF00107	Zinc-binding dehydrogenase
SPH21_RS05230	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS05235	PF00081	Iron/manganese superoxide dismutases, alpha-hairpin domain
SPH21_RS05235	PF02777	Iron/manganese superoxide dismutases, C-terminal domain
SPH21_RS05240	PF14437	MafB19-like deaminase
SPH21_RS05245	PF01588	Putative tRNA binding domain
SPH21_RS05250	PF00005	ABC transporter
SPH21_RS05250	PF02687	FtsX-like permease family
SPH21_RS05250	PF12704	MacB-like periplasmic core domain
SPH21_RS05255	PF10518	TAT (twin-arginine translocation) pathway signal sequence
SPH21_RS05255	PF00149	Calcineurin-like phosphoesterase
SPH21_RS05260	PF00762	Ferrochelatase
SPH21_RS05265	PF02401	LytB protein
SPH21_RS05270	PF02113	D-Ala-D-Ala carboxypeptidase 3 (S13) family
SPH21_RS05280	PF01118	Semialdehyde dehydrogenase, NAD binding domain
SPH21_RS05280	PF02774	Semialdehyde dehydrogenase, dimerisation domain
SPH21_RS05300	PF01370	NAD dependent epimerase/dehydratase family
SPH21_RS05305	PF01709	Transcriptional regulator
SPH21_RS05315	PF01244	Membrane dipeptidase (Peptidase family M19)
SPH21_RS05320	PF00176	SNF2 family N-terminal domain
SPH21_RS05320	PF12419	SNF2 Helicase protein 
SPH21_RS05320	PF00271	Helicase conserved C-terminal domain
SPH21_RS05325	PF07691	PA14 domain
SPH21_RS05325	PF00728	Glycosyl hydrolase family 20, catalytic domain
SPH21_RS05325	PF02838	Glycosyl hydrolase family 20, domain 2
SPH21_RS05335	PF02390	Putative methyltransferase 
SPH21_RS05340	PF01546	Peptidase family M20/M25/M40
SPH21_RS05340	PF07687	Peptidase dimerisation domain
SPH21_RS05345	PF17785	PUA-like domain
SPH21_RS05345	PF10672	S-adenosylmethionine-dependent methyltransferase
SPH21_RS05350	PF04542	Sigma-70 region 2 
SPH21_RS05350	PF08281	Sigma-70, region 4
SPH21_RS05365	PF04738	Lantibiotic dehydratase, N terminus
SPH21_RS05365	PF14028	Lantibiotic biosynthesis dehydratase C-term
SPH21_RS05370	PF06580	Histidine kinase
SPH21_RS05370	PF00672	HAMP domain
SPH21_RS05370	PF02743	Cache domain
SPH21_RS05370	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS05375	PF04397	LytTr DNA-binding domain
SPH21_RS05375	PF00072	Response regulator receiver domain
SPH21_RS05385	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS05385	PF00593	TonB dependent receptor
SPH21_RS05395	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS05395	PF00593	TonB dependent receptor
SPH21_RS05420	PF00593	TonB dependent receptor
SPH21_RS05420	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS05435	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS05435	PF00593	TonB dependent receptor
SPH21_RS05440	PF01678	Diaminopimelate epimerase
SPH21_RS05445	PF04679	ATP dependent DNA ligase C terminal region        
SPH21_RS05445	PF04675	DNA ligase N terminus
SPH21_RS05445	PF01068	ATP dependent DNA ligase domain
SPH21_RS05450	PF01068	ATP dependent DNA ligase domain
SPH21_RS05450	PF04675	DNA ligase N terminus
SPH21_RS05450	PF04679	ATP dependent DNA ligase C terminal region        
SPH21_RS05455	PF00271	Helicase conserved C-terminal domain
SPH21_RS05455	PF00270	DEAD/DEAH box helicase
SPH21_RS05455	PF08494	DEAD/H associated
SPH21_RS05470	PF13426	PAS domain
SPH21_RS05470	PF00672	HAMP domain
SPH21_RS05470	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS05470	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS05475	PF09984	Uncharacterised signal transduction histidine kinase domain (DUF2222)
SPH21_RS05475	PF01627	Hpt domain
SPH21_RS05475	PF00072	Response regulator receiver domain
SPH21_RS05475	PF00672	HAMP domain
SPH21_RS05475	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS05475	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS05480	PF00072	Response regulator receiver domain
SPH21_RS05485	PF03705	CheR methyltransferase, all-alpha domain
SPH21_RS05485	PF01739	CheR methyltransferase, SAM binding domain
SPH21_RS05490	PF00348	Polyprenyl synthetase
SPH21_RS05495	PF03741	Integral membrane protein TerC family
SPH21_RS05515	PF02786	Carbamoyl-phosphate synthase L chain, ATP binding domain
SPH21_RS05515	PF02787	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
SPH21_RS05515	PF02142	MGS-like domain
SPH21_RS05520	PF00873	AcrB/AcrD/AcrF family
SPH21_RS05525	PF00529	HlyD membrane-fusion protein of T1SS
SPH21_RS05525	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
SPH21_RS05535	PF18073	Rubredoxin metal binding domain
SPH21_RS05540	PF00575	S1 RNA binding domain
SPH21_RS05540	PF10150	Ribonuclease E/G family
SPH21_RS05550	PF00216	Bacterial DNA-binding protein
SPH21_RS05555	PF00730	HhH-GPD superfamily base excision DNA repair protein
SPH21_RS05555	PF14815	NUDIX domain
SPH21_RS05560	PF00436	Single-strand binding protein family
SPH21_RS05565	PF01336	OB-fold nucleic acid binding domain
SPH21_RS05565	PF02938	GAD domain
SPH21_RS05565	PF00152	tRNA synthetases class II (D, K and N) 
SPH21_RS05570	PF02780	Transketolase, C-terminal domain
SPH21_RS05570	PF02779	Transketolase, pyrimidine binding domain
SPH21_RS05570	PF13292	1-deoxy-D-xylulose-5-phosphate synthase
SPH21_RS05575	PF02616	Segregation and condensation protein ScpA
SPH21_RS05580	PF00464	Serine hydroxymethyltransferase
SPH21_RS05585	PF00156	Phosphoribosyl transferase domain
SPH21_RS05590	PF04055	Radical SAM superfamily
SPH21_RS05595	PF01979	Amidohydrolase family
SPH21_RS05600	PF00708	Acylphosphatase
SPH21_RS05625	PF02416	mttA/Hcf106 family
SPH21_RS05630	PF01476	LysM domain
SPH21_RS05630	PF01464	Transglycosylase SLT domain
SPH21_RS05635	PF00156	Phosphoribosyl transferase domain
SPH21_RS05640	PF00877	NlpC/P60 family
SPH21_RS05645	PF00676	Dehydrogenase E1 component
SPH21_RS05650	PF02817	e3 binding domain
SPH21_RS05650	PF00198	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
SPH21_RS05650	PF00364	Biotin-requiring enzyme
SPH21_RS05655	PF01663	Type I phosphodiesterase / nucleotide pyrophosphatase
SPH21_RS05665	PF04389	Peptidase family M28
SPH21_RS05665	PF04151	Bacterial pre-peptidase C-terminal domain
SPH21_RS05670	PF17773	UPF0176 acylphosphatase like domain
SPH21_RS05670	PF12368	Rhodanase C-terminal
SPH21_RS05670	PF00581	Rhodanese-like domain
SPH21_RS05680	PF00691	OmpA family
SPH21_RS05685	PF01042	Endoribonuclease L-PSP
SPH21_RS05690	PF00270	DEAD/DEAH box helicase
SPH21_RS05690	PF17191	RecG wedge domain
SPH21_RS05690	PF00271	Helicase conserved C-terminal domain
SPH21_RS05695	PF13167	GTP-binding GTPase N-terminal
SPH21_RS05695	PF16360	GTP-binding GTPase Middle Region
SPH21_RS05695	PF01926	50S ribosome-binding GTPase
SPH21_RS05700	PF02033	Ribosome-binding factor A
SPH21_RS05705	PF03588	Leucyl/phenylalanyl-tRNA protein transferase
SPH21_RS05710	PF03458	UPF0126 domain
SPH21_RS05715	PF01327	Polypeptide deformylase
SPH21_RS05720	PF00675	Insulinase (Peptidase family M16)
SPH21_RS05720	PF05193	Peptidase M16 inactive domain
SPH21_RS05735	PF01351	Ribonuclease HII
SPH21_RS05740	PF08669	Glycine cleavage T-protein C-terminal barrel domain
SPH21_RS05740	PF01571	Aminomethyltransferase folate-binding domain
SPH21_RS05745	PF04029	2-phosphosulpholactate phosphatase
SPH21_RS05750	PF01451	Low molecular weight phosphotyrosine protein phosphatase
SPH21_RS05755	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS05755	PF00989	PAS fold
SPH21_RS05755	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS05760	PF00158	Sigma-54 interaction domain
SPH21_RS05760	PF00072	Response regulator receiver domain
SPH21_RS05760	PF02954	Bacterial regulatory protein, Fis family
SPH21_RS05775	PF00005	ABC transporter
SPH21_RS05780	PF02687	FtsX-like permease family
SPH21_RS05780	PF12704	MacB-like periplasmic core domain
SPH21_RS05785	PF02687	FtsX-like permease family
SPH21_RS05785	PF12704	MacB-like periplasmic core domain
SPH21_RS05795	PF12704	MacB-like periplasmic core domain
SPH21_RS05795	PF02687	FtsX-like permease family
SPH21_RS05810	PF01654	Cytochrome bd terminal oxidase subunit I
SPH21_RS05820	PF00593	TonB dependent receptor
SPH21_RS05820	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS05835	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS05835	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS05840	PF01799	[2Fe-2S] binding domain
SPH21_RS05840	PF00111	2Fe-2S iron-sulfur cluster binding domain
SPH21_RS05845	PF13442	Cytochrome C oxidase, cbb3-type, subunit III 
SPH21_RS05845	PF00034	Cytochrome c
SPH21_RS05845	PF02738	Molybdopterin-binding domain of aldehyde dehydrogenase
SPH21_RS05850	PF09905	DNA-binding protein VF530
SPH21_RS05855	PF03446	NAD binding domain of 6-phosphogluconate dehydrogenase
SPH21_RS05855	PF14833	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
SPH21_RS05860	PF07690	Major Facilitator Superfamily
SPH21_RS05895	PF00005	ABC transporter
SPH21_RS05895	PF02687	FtsX-like permease family
SPH21_RS05895	PF12704	MacB-like periplasmic core domain
SPH21_RS05900	PF02687	FtsX-like permease family
SPH21_RS05900	PF12704	MacB-like periplasmic core domain
SPH21_RS05910	PF13606	Ankyrin repeat
SPH21_RS05910	PF12796	Ankyrin repeats (3 copies)
SPH21_RS05915	PF12833	Helix-turn-helix domain
SPH21_RS05930	PF13673	Acetyltransferase (GNAT) domain
SPH21_RS05935	PF01934	Protein of unknown function DUF86
SPH21_RS05970	PF12704	MacB-like periplasmic core domain
SPH21_RS05970	PF02687	FtsX-like permease family
SPH21_RS05995	PF03831	PhnA domain
SPH21_RS05995	PF08274	PhnA Zinc-Ribbon 
SPH21_RS06005	PF00005	ABC transporter
SPH21_RS06005	PF02687	FtsX-like permease family
SPH21_RS06005	PF12704	MacB-like periplasmic core domain
SPH21_RS06015	PF01554	MatE
SPH21_RS06020	PF00107	Zinc-binding dehydrogenase
SPH21_RS06020	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS06025	PF12704	MacB-like periplasmic core domain
SPH21_RS06025	PF02687	FtsX-like permease family
SPH21_RS06045	PF12704	MacB-like periplasmic core domain
SPH21_RS06045	PF00005	ABC transporter
SPH21_RS06045	PF02687	FtsX-like permease family
SPH21_RS06055	PF00375	Sodium:dicarboxylate symporter family
SPH21_RS06065	PF02457	DisA bacterial checkpoint controller nucleotide-binding
SPH21_RS06070	PF06491	Disulphide isomerase
SPH21_RS06085	PF00670	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
SPH21_RS06085	PF05221	S-adenosyl-L-homocysteine hydrolase
SPH21_RS06095	PF03740	Pyridoxal phosphate biosynthesis protein PdxJ
SPH21_RS06100	PF00334	Nucleoside diphosphate kinase
SPH21_RS06105	PF01368	DHH family
SPH21_RS06105	PF02272	DHHA1 domain
SPH21_RS06110	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
SPH21_RS06110	PF01346	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
SPH21_RS06115	PF01026	TatD related DNase
SPH21_RS06120	PF00710	Asparaginase, N-terminal
SPH21_RS06120	PF17763	Glutaminase/Asparaginase C-terminal domain
SPH21_RS06125	PF00326	Prolyl oligopeptidase family
SPH21_RS06125	PF02897	Prolyl oligopeptidase, N-terminal beta-propeller domain
SPH21_RS06145	PF01938	TRAM domain
SPH21_RS06145	PF05958	tRNA (Uracil-5-)-methyltransferase
SPH21_RS06150	PF01966	HD domain
SPH21_RS06150	PF13286	Phosphohydrolase-associated domain
SPH21_RS06155	PF01204	Trehalase
SPH21_RS06160	PF08450	SMP-30/Gluconolactonase/LRE-like region
SPH21_RS06175	PF01327	Polypeptide deformylase
SPH21_RS06185	PF00109	Beta-ketoacyl synthase, N-terminal domain
SPH21_RS06185	PF16197	Ketoacyl-synthetase C-terminal extension
SPH21_RS06185	PF00550	Phosphopantetheine attachment site
SPH21_RS06185	PF00501	AMP-binding enzyme
SPH21_RS06185	PF02801	Beta-ketoacyl synthase, C-terminal domain
SPH21_RS06185	PF00668	Condensation domain
SPH21_RS06185	PF13193	AMP-binding enzyme C-terminal domain
SPH21_RS06185	PF00202	Aminotransferase class-III
SPH21_RS06190	PF00067	Cytochrome P450
SPH21_RS06200	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS06200	PF00593	TonB dependent receptor
SPH21_RS06205	PF14322	Starch-binding associating with outer membrane
SPH21_RS06205	PF07980	SusD family
SPH21_RS06215	PF12833	Helix-turn-helix domain
SPH21_RS06220	PF02627	Carboxymuconolactone decarboxylase family
SPH21_RS06225	PF00326	Prolyl oligopeptidase family
SPH21_RS06225	PF07676	WD40-like Beta Propeller Repeat
SPH21_RS06225	PF00930	Dipeptidyl peptidase IV (DPP IV) N-terminal region
SPH21_RS06280	PF07980	SusD family
SPH21_RS06280	PF14322	Starch-binding associating with outer membrane
SPH21_RS06285	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS06285	PF00593	TonB dependent receptor
SPH21_RS06360	PF02130	Uncharacterized protein family UPF0054
SPH21_RS06370	PF02646	RmuC family
SPH21_RS06375	PF02769	AIR synthase related protein, C-terminal domain
SPH21_RS06375	PF00586	AIR synthase related protein, N-terminal domain
SPH21_RS06380	PF02445	Quinolinate synthetase A protein
SPH21_RS06385	PF00890	FAD binding domain
SPH21_RS06385	PF02910	Fumarate reductase flavoprotein C-term
SPH21_RS06390	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS06400	PF01134	Glucose inhibited division protein A
SPH21_RS06400	PF13932	GidA associated domain
SPH21_RS06405	PF16326	ABC transporter C-terminal domain
SPH21_RS06405	PF12848	ABC transporter
SPH21_RS06405	PF00005	ABC transporter
SPH21_RS06410	PF04379	ApaG domain 
SPH21_RS06415	PF01207	Dihydrouridine synthase (Dus)
SPH21_RS06430	PF03129	Anticodon binding domain
SPH21_RS06430	PF13393	Histidyl-tRNA synthetase
SPH21_RS06440	PF01037	Lrp/AsnC ligand binding domain
SPH21_RS06445	PF02779	Transketolase, pyrimidine binding domain
SPH21_RS06445	PF00364	Biotin-requiring enzyme
SPH21_RS06445	PF02780	Transketolase, C-terminal domain
SPH21_RS06450	PF12705	PD-(D/E)XK nuclease superfamily
SPH21_RS06455	PF12705	PD-(D/E)XK nuclease superfamily
SPH21_RS06455	PF13361	UvrD-like helicase C-terminal domain
SPH21_RS06455	PF00580	UvrD/REP helicase N-terminal domain
SPH21_RS06470	PF02638	Glycosyl hydrolase-like 10
SPH21_RS06480	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS06480	PF00672	HAMP domain
SPH21_RS06480	PF00989	PAS fold
SPH21_RS06480	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS06485	PF00698	Acyl transferase domain
SPH21_RS06490	PF01227	GTP cyclohydrolase I
SPH21_RS06505	PF02621	Menaquinone biosynthesis
SPH21_RS06510	PF00723	Glycosyl hydrolases family 15
SPH21_RS06515	PF00982	Glycosyltransferase family 20
SPH21_RS06520	PF00886	Ribosomal protein S16
SPH21_RS06525	PF01782	RimM N-terminal domain
SPH21_RS06530	PF01746	tRNA (Guanine-1)-methyltransferase
SPH21_RS06535	PF01245	Ribosomal protein L19
SPH21_RS06540	PF01966	HD domain
SPH21_RS06550	PF02926	THUMP domain
SPH21_RS06550	PF10672	S-adenosylmethionine-dependent methyltransferase
SPH21_RS06550	PF01170	Putative RNA methylase family UPF0020
SPH21_RS06560	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS06560	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS06565	PF00072	Response regulator receiver domain
SPH21_RS06565	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS06570	PF01062	Bestrophin, RFP-TM, chloride channel
SPH21_RS06575	PF00171	Aldehyde dehydrogenase family
SPH21_RS06585	PF02679	(2R)-phospho-3-sulfolactate synthase (ComA)
SPH21_RS06590	PF08501	Shikimate dehydrogenase substrate binding domain
SPH21_RS06590	PF18317	Shikimate 5'-dehydrogenase C-terminal domain
SPH21_RS06590	PF01488	Shikimate / quinate 5-dehydrogenase
SPH21_RS06600	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS06605	PF12704	MacB-like periplasmic core domain
SPH21_RS06605	PF02687	FtsX-like permease family
SPH21_RS06610	PF03461	TRCF domain
SPH21_RS06610	PF00270	DEAD/DEAH box helicase
SPH21_RS06610	PF00271	Helicase conserved C-terminal domain
SPH21_RS06610	PF02559	CarD-like/TRCF domain
SPH21_RS06610	PF17757	UvrB interaction domain
SPH21_RS06630	PF00474	Sodium:solute symporter family
SPH21_RS06635	PF01263	Aldose 1-epimerase
SPH21_RS06640	PF10509	Galactokinase galactose-binding signature
SPH21_RS06640	PF08544	GHMP kinases C terminal 
SPH21_RS06640	PF00288	GHMP kinases N terminal domain
SPH21_RS06645	PF03551	Transcriptional regulator PadR-like family
SPH21_RS06655	PF01225	Mur ligase family, catalytic domain
SPH21_RS06655	PF08245	Mur ligase middle domain
SPH21_RS06655	PF02875	Mur ligase family, glutamate ligase domain
SPH21_RS06665	PF00224	Pyruvate kinase, barrel domain
SPH21_RS06665	PF02887	Pyruvate kinase, alpha/beta domain
SPH21_RS06665	PF00391	PEP-utilising enzyme, mobile domain
SPH21_RS06675	PF00550	Phosphopantetheine attachment site
SPH21_RS06680	PF02801	Beta-ketoacyl synthase, C-terminal domain
SPH21_RS06680	PF00109	Beta-ketoacyl synthase, N-terminal domain
SPH21_RS06685	PF00035	Double-stranded RNA binding motif
SPH21_RS06685	PF14622	Ribonuclease-III-like
SPH21_RS06690	PF16193	AAA C-terminal domain
SPH21_RS06690	PF00004	ATPase family associated with various cellular activities (AAA)
SPH21_RS06690	PF12002	MgsA AAA+ ATPase C terminal
SPH21_RS06700	PF11818	C-terminal domain of tail specific protease (DUF3340)
SPH21_RS06700	PF00595	PDZ domain
SPH21_RS06700	PF03572	Peptidase family S41
SPH21_RS06700	PF17804	Tail specific protease N-terminal domain
SPH21_RS06705	PF00881	Nitroreductase family
SPH21_RS06715	PF01592	NifU-like N terminal domain
SPH21_RS06715	PF01106	NifU-like domain
SPH21_RS06720	PF01883	Iron-sulfur cluster assembly protein
SPH21_RS06720	PF10609	NUBPL iron-transfer P-loop NTPase
SPH21_RS06725	PF00912	Transglycosylase
SPH21_RS06730	PF00156	Phosphoribosyl transferase domain
SPH21_RS06735	PF02666	Phosphatidylserine decarboxylase
SPH21_RS06740	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS06740	PF16736	Single Cache-like 
SPH21_RS06740	PF00989	PAS fold
SPH21_RS06740	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS06750	PF01384	Phosphate transporter family
SPH21_RS06775	PF01784	NIF3 (NGG1p interacting factor 3)
SPH21_RS06790	PF07687	Peptidase dimerisation domain
SPH21_RS06790	PF01546	Peptidase family M20/M25/M40
SPH21_RS06795	PF02580	D-Tyr-tRNA(Tyr) deacylase
SPH21_RS06800	PF03819	MazG nucleotide pyrophosphohydrolase domain
SPH21_RS06805	PF00899	ThiF family
SPH21_RS06810	PF06968	Biotin and Thiamin Synthesis associated domain
SPH21_RS06810	PF04055	Radical SAM superfamily
SPH21_RS06815	PF05690	Thiazole biosynthesis protein ThiG
SPH21_RS06820	PF02581	Thiamine monophosphate synthase
SPH21_RS06830	PF13667	ThiC-associated domain 
SPH21_RS06830	PF01964	Radical SAM ThiC family
SPH21_RS06845	PF03372	Endonuclease/Exonuclease/phosphatase family
SPH21_RS06850	PF00160	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
SPH21_RS06875	PF13180	PDZ domain
SPH21_RS06875	PF03572	Peptidase family S41
SPH21_RS06880	PF00072	Response regulator receiver domain
SPH21_RS06880	PF04397	LytTr DNA-binding domain
SPH21_RS06885	PF06580	Histidine kinase
SPH21_RS06910	PF02910	Fumarate reductase flavoprotein C-term
SPH21_RS06910	PF00890	FAD binding domain
SPH21_RS06920	PF13180	PDZ domain
SPH21_RS06975	PF17773	UPF0176 acylphosphatase like domain
SPH21_RS06975	PF12368	Rhodanase C-terminal
SPH21_RS06975	PF00581	Rhodanese-like domain
SPH21_RS06985	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS06985	PF00593	TonB dependent receptor
SPH21_RS06990	PF07980	SusD family
SPH21_RS06990	PF14322	Starch-binding associating with outer membrane
SPH21_RS07005	PF14310	Fibronectin type III-like domain
SPH21_RS07005	PF00933	Glycosyl hydrolase family 3 N terminal domain
SPH21_RS07005	PF01915	Glycosyl hydrolase family 3 C-terminal domain
SPH21_RS07020	PF17676	LD-carboxypeptidase C-terminal domain
SPH21_RS07020	PF02016	LD-carboxypeptidase N-terminal domain
SPH21_RS07025	PF01588	Putative tRNA binding domain
SPH21_RS07025	PF08264	Anticodon-binding domain of tRNA
SPH21_RS07025	PF09334	tRNA synthetases class I (M)
SPH21_RS07030	PF14821	Threonine synthase N terminus
SPH21_RS07030	PF00291	Pyridoxal-phosphate dependent enzyme
SPH21_RS07035	PF08544	GHMP kinases C terminal 
SPH21_RS07035	PF00288	GHMP kinases N terminal domain
SPH21_RS07040	PF01842	ACT domain
SPH21_RS07040	PF00696	Amino acid kinase family
SPH21_RS07040	PF03447	Homoserine dehydrogenase, NAD binding domain
SPH21_RS07040	PF00742	Homoserine dehydrogenase
SPH21_RS07040	PF13840	ACT domain 
SPH21_RS07045	PF01765	Ribosome recycling factor
SPH21_RS07065	PF03193	RsgA GTPase
SPH21_RS07065	PF16745	RsgA N-terminal domain
SPH21_RS07070	PF00749	tRNA synthetases class I (E and Q), catalytic domain
SPH21_RS07075	PF08448	PAS fold
SPH21_RS07075	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS07075	PF13188	PAS domain
SPH21_RS07075	PF00072	Response regulator receiver domain
SPH21_RS07075	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS07085	PF07690	Major Facilitator Superfamily
SPH21_RS07100	PF00448	SRP54-type protein, GTPase domain
SPH21_RS07100	PF02881	SRP54-type protein, helical bundle domain
SPH21_RS07100	PF02978	Signal peptide binding domain
SPH21_RS07105	PF13335	Magnesium chelatase, subunit ChlI C-terminal
SPH21_RS07105	PF01078	Magnesium chelatase, subunit ChlI
SPH21_RS07110	PF00889	Elongation factor TS
SPH21_RS07115	PF00318	Ribosomal protein S2
SPH21_RS07120	PF00380	Ribosomal protein S9/S16
SPH21_RS07125	PF00572	Ribosomal protein L13
SPH21_RS07130	PF01554	MatE
SPH21_RS07145	PF00472	RF-1 domain
SPH21_RS07145	PF03462	PCRF domain
SPH21_RS07150	PF07690	Major Facilitator Superfamily
SPH21_RS07155	PF00149	Calcineurin-like phosphoesterase
SPH21_RS07160	PF00703	Glycosyl hydrolases family 2
SPH21_RS07160	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS07160	PF18368	Exo-beta-D-glucosaminidase Ig-fold domain
SPH21_RS07165	PF00326	Prolyl oligopeptidase family
SPH21_RS07165	PF02897	Prolyl oligopeptidase, N-terminal beta-propeller domain
SPH21_RS07175	PF02609	Exonuclease VII small subunit
SPH21_RS07185	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS07185	PF00593	TonB dependent receptor
SPH21_RS07195	PF00155	Aminotransferase class I and II
SPH21_RS07200	PF01409	tRNA synthetases class II core domain (F)
SPH21_RS07200	PF02912	Aminoacyl tRNA synthetase class II, N-terminal domain
SPH21_RS07210	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS07210	PF16859	Tetracyclin repressor-like, C-terminal domain
SPH21_RS07215	PF00474	Sodium:solute symporter family
SPH21_RS07230	PF01725	Ham1 family
SPH21_RS07245	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS07245	PF01548	Transposase
SPH21_RS07250	PF05698	Bacterial trigger factor protein (TF) C-terminus
SPH21_RS07260	PF01406	tRNA synthetases class I (C) catalytic domain
SPH21_RS07260	PF09190	DALR domain
SPH21_RS07280	PF01119	DNA mismatch repair protein, C-terminal domain
SPH21_RS07280	PF08676	MutL C terminal dimerisation domain
SPH21_RS07295	PF00085	Thioredoxin
SPH21_RS07300	PF10417	C-terminal domain of 1-Cys peroxiredoxin
SPH21_RS07300	PF00578	AhpC/TSA family
SPH21_RS07305	PF01541	GIY-YIG catalytic domain
SPH21_RS07320	PF12833	Helix-turn-helix domain
SPH21_RS07330	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
SPH21_RS07335	PF00873	AcrB/AcrD/AcrF family
SPH21_RS07340	PF02321	Outer membrane efflux protein
SPH21_RS07350	PF00155	Aminotransferase class I and II
SPH21_RS07350	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS07375	PF03352	Methyladenine glycosylase
SPH21_RS07380	PF01035	6-O-methylguanine DNA methyltransferase, DNA binding domain
SPH21_RS07385	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
SPH21_RS07395	PF02843	Phosphoribosylglycinamide synthetase, C domain
SPH21_RS07395	PF01071	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
SPH21_RS07395	PF02844	Phosphoribosylglycinamide synthetase, N domain
SPH21_RS07410	PF02617	ATP-dependent Clp protease adaptor protein ClpS
SPH21_RS07430	PF04715	Anthranilate synthase component I, N terminal region
SPH21_RS07430	PF00425	chorismate binding enzyme
SPH21_RS07435	PF00117	Glutamine amidotransferase class-I
SPH21_RS07440	PF00218	Indole-3-glycerol phosphate synthase
SPH21_RS07445	PF02585	GlcNAc-PI de-N-acetylase
SPH21_RS07445	PF01182	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
SPH21_RS07465	PF01467	Cytidylyltransferase-like
SPH21_RS07470	PF00625	Guanylate kinase
SPH21_RS07475	PF08340	Domain of unknown function (DUF1732)
SPH21_RS07475	PF03755	YicC-like family, N-terminal region 
SPH21_RS07485	PF00675	Insulinase (Peptidase family M16)
SPH21_RS07485	PF05193	Peptidase M16 inactive domain
SPH21_RS07490	PF00691	OmpA family
SPH21_RS07495	PF01612	3'-5' exonuclease
SPH21_RS07495	PF02739	5'-3' exonuclease, N-terminal resolvase-like domain
SPH21_RS07495	PF01367	5'-3' exonuclease, C-terminal SAM fold
SPH21_RS07495	PF00476	DNA polymerase family A
SPH21_RS07510	PF02575	YbaB/EbfC DNA-binding family
SPH21_RS07515	PF11954	Domain of unknown function (DUF3471)
SPH21_RS07515	PF00144	Beta-lactamase
SPH21_RS07525	PF10415	Fumarase C C-terminus
SPH21_RS07525	PF00206	Lyase
SPH21_RS07585	PF00199	Catalase
SPH21_RS07585	PF06628	Catalase-related immune-responsive
SPH21_RS07590	PF03466	LysR substrate binding domain
SPH21_RS07590	PF00126	Bacterial regulatory helix-turn-helix protein, lysR family
SPH21_RS07600	PF01262	Alanine dehydrogenase/PNT, C-terminal domain
SPH21_RS07600	PF05222	Alanine dehydrogenase/PNT, N-terminal domain
SPH21_RS07610	PF00072	Response regulator receiver domain
SPH21_RS07610	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS07615	PF01966	HD domain
SPH21_RS07620	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS07620	PF04613	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD  
SPH21_RS07625	PF07977	FabA-like domain
SPH21_RS07625	PF03331	UDP-3-O-acyl N-acetylglycosamine deacetylase
SPH21_RS07630	PF13720	Udp N-acetylglucosamine O-acyltransferase; Domain 2
SPH21_RS07630	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS07635	PF13732	Domain of unknown function (DUF4162)
SPH21_RS07635	PF00005	ABC transporter
SPH21_RS07640	PF08207	Elongation factor P (EF-P) KOW-like domain
SPH21_RS07640	PF09285	Elongation factor P, C-terminal
SPH21_RS07640	PF01132	Elongation factor P (EF-P) OB domain
SPH21_RS07645	PF01812	5-formyltetrahydrofolate cyclo-ligase family
SPH21_RS07665	PF13247	4Fe-4S dicluster domain
SPH21_RS07665	PF00037	4Fe-4S binding domain
SPH21_RS07690	PF00116	Cytochrome C oxidase subunit II, periplasmic domain
SPH21_RS07695	PF00115	Cytochrome C and Quinol oxidase polypeptide I
SPH21_RS07705	PF01040	UbiA prenyltransferase family
SPH21_RS07710	PF00510	Cytochrome c oxidase subunit III
SPH21_RS07715	PF00510	Cytochrome c oxidase subunit III
SPH21_RS07730	PF04238	Protein of unknown function (DUF420)
SPH21_RS07750	PF00908	dTDP-4-dehydrorhamnose 3,5-epimerase
SPH21_RS07760	PF00326	Prolyl oligopeptidase family
SPH21_RS07765	PF00989	PAS fold
SPH21_RS07765	PF00672	HAMP domain
SPH21_RS07765	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS07765	PF18698	Histidine kinase sensor domain
SPH21_RS07765	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS07770	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS07770	PF00072	Response regulator receiver domain
SPH21_RS07775	PF01272	Transcription elongation factor, GreA/GreB, C-term
SPH21_RS07775	PF03449	Transcription elongation factor, N-terminal
SPH21_RS07780	PF01230	HIT domain
SPH21_RS07785	PF02075	Crossover junction endodeoxyribonuclease RuvC
SPH21_RS07805	PF02773	S-adenosylmethionine synthetase, C-terminal domain
SPH21_RS07805	PF00438	S-adenosylmethionine synthetase, N-terminal domain
SPH21_RS07805	PF02772	S-adenosylmethionine synthetase, central domain
SPH21_RS07810	PF00781	Diacylglycerol kinase catalytic domain
SPH21_RS07835	PF03544	Gram-negative bacterial TonB protein C-terminal
SPH21_RS07855	PF00507	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
SPH21_RS07860	PF01058	NADH ubiquinone oxidoreductase, 20 Kd subunit
SPH21_RS07865	PF00329	Respiratory-chain NADH dehydrogenase, 30 Kd subunit
SPH21_RS07870	PF00346	Respiratory-chain NADH dehydrogenase, 49 Kd subunit
SPH21_RS07880	PF10531	SLBB domain
SPH21_RS07880	PF10589	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
SPH21_RS07880	PF01512	Respiratory-chain NADH dehydrogenase 51 Kd subunit
SPH21_RS07885	PF09326	NADH-ubiquinone oxidoreductase subunit G, C-terminal
SPH21_RS07885	PF10588	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
SPH21_RS07885	PF00384	Molybdopterin oxidoreductase
SPH21_RS07890	PF00146	NADH dehydrogenase
SPH21_RS07895	PF12838	4Fe-4S dicluster domain
SPH21_RS07900	PF00499	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
SPH21_RS07905	PF00420	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
SPH21_RS07910	PF00361	Proton-conducting membrane transporter
SPH21_RS07910	PF00662	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
SPH21_RS07915	PF00361	Proton-conducting membrane transporter
SPH21_RS07920	PF00361	Proton-conducting membrane transporter
SPH21_RS07925	PF09335	SNARE associated Golgi protein
SPH21_RS07930	PF00719	Inorganic pyrophosphatase
SPH21_RS07935	PF01595	Cyclin M transmembrane N-terminal domain
SPH21_RS07935	PF03471	Transporter associated domain
SPH21_RS07935	PF00571	CBS domain
SPH21_RS07940	PF04452	RNA methyltransferase
SPH21_RS07945	PF02153	Prephenate dehydrogenase
SPH21_RS07950	PF00155	Aminotransferase class I and II
SPH21_RS07955	PF00664	ABC transporter transmembrane region
SPH21_RS07955	PF00005	ABC transporter
SPH21_RS07960	PF00009	Elongation factor Tu GTP binding domain
SPH21_RS07960	PF11987	Translation-initiation factor 2
SPH21_RS07960	PF04760	Translation initiation factor IF-2, N-terminal region
SPH21_RS07965	PF00575	S1 RNA binding domain
SPH21_RS07965	PF08529	NusA N-terminal domain
SPH21_RS07965	PF13184	NusA-like KH domain
SPH21_RS07970	PF02576	RimP N-terminal domain
SPH21_RS07980	PF10282	Lactonase, 7-bladed beta-propeller
SPH21_RS07985	PF13439	Glycosyltransferase Family 4
SPH21_RS07985	PF00534	Glycosyl transferases group 1
SPH21_RS07990	PF00144	Beta-lactamase
SPH21_RS08000	PF10459	Peptidase S46
SPH21_RS08010	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS08010	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS08020	PF01171	PP-loop family
SPH21_RS08020	PF11734	TilS substrate C-terminal domain
SPH21_RS08040	PF00535	Glycosyl transferase family 2
SPH21_RS08070	PF00679	Elongation factor G C-terminus
SPH21_RS08070	PF14492	Elongation Factor G, domain II
SPH21_RS08070	PF00009	Elongation factor Tu GTP binding domain
SPH21_RS08070	PF03144	Elongation factor Tu domain 2
SPH21_RS08075	PF02542	YgbB family
SPH21_RS08080	PF03781	Sulfatase-modifying factor enzyme 1
SPH21_RS08090	PF00534	Glycosyl transferases group 1
SPH21_RS08090	PF08323	Starch synthase catalytic domain
SPH21_RS08095	PF02569	Pantoate-beta-alanine ligase
SPH21_RS08100	PF02261	Aspartate decarboxylase
SPH21_RS08105	PF00072	Response regulator receiver domain
SPH21_RS08105	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS08110	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS08110	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS08110	PF00672	HAMP domain
SPH21_RS08115	PF14493	Helix-turn-helix domain
SPH21_RS08115	PF05970	PIF1-like helicase
SPH21_RS08120	PF11838	ERAP1-like C-terminal domain
SPH21_RS08120	PF01433	Peptidase family M1 domain
SPH21_RS08130	PF02771	Acyl-CoA dehydrogenase, N-terminal domain
SPH21_RS08130	PF00441	Acyl-CoA dehydrogenase, C-terminal domain
SPH21_RS08130	PF02770	Acyl-CoA dehydrogenase, middle domain
SPH21_RS08140	PF00986	DNA gyrase B subunit, carboxyl terminus
SPH21_RS08140	PF00204	DNA gyrase B
SPH21_RS08140	PF01751	Toprim domain
SPH21_RS08140	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS08145	PF00551	Formyl transferase
SPH21_RS08145	PF01842	ACT domain
SPH21_RS08150	PF00593	TonB dependent receptor
SPH21_RS08150	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS08160	PF00248	Aldo/keto reductase family
SPH21_RS08170	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS08170	PF01548	Transposase
SPH21_RS08175	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS08175	PF01548	Transposase
SPH21_RS08180	PF00521	DNA gyrase/topoisomerase IV, subunit A
SPH21_RS08185	PF01625	Peptide methionine sulfoxide reductase
SPH21_RS08195	PF04205	FMN-binding domain
SPH21_RS08195	PF00890	FAD binding domain
SPH21_RS08215	PF07980	SusD family
SPH21_RS08215	PF14322	Starch-binding associating with outer membrane
SPH21_RS08220	PF00593	TonB dependent receptor
SPH21_RS08220	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS08245	PF10672	S-adenosylmethionine-dependent methyltransferase
SPH21_RS08245	PF02926	THUMP domain
SPH21_RS08245	PF01170	Putative RNA methylase family UPF0020
SPH21_RS08250	PF00005	ABC transporter
SPH21_RS08250	PF09383	NIL domain
SPH21_RS08255	PF02405	Permease MlaE
SPH21_RS08260	PF00106	short chain dehydrogenase
SPH21_RS08275	PF06271	RDD family
SPH21_RS08280	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS08290	PF13533	Biotin-lipoyl like
SPH21_RS08295	PF07690	Major Facilitator Superfamily
SPH21_RS08300	PF01609	Transposase DDE domain
SPH21_RS08315	PF03441	FAD binding domain of DNA photolyase
SPH21_RS08315	PF00875	DNA photolyase
SPH21_RS08320	PF08338	Domain of unknown function (DUF1731)
SPH21_RS08320	PF01370	NAD dependent epimerase/dehydratase family
SPH21_RS08330	PF03441	FAD binding domain of DNA photolyase
SPH21_RS08330	PF00875	DNA photolyase
SPH21_RS08335	PF02779	Transketolase, pyrimidine binding domain
SPH21_RS08335	PF16078	2-oxoglutarate dehydrogenase N-terminus
SPH21_RS08335	PF00676	Dehydrogenase E1 component
SPH21_RS08335	PF16870	2-oxoglutarate dehydrogenase C-terminal
SPH21_RS08340	PF00364	Biotin-requiring enzyme
SPH21_RS08340	PF00198	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
SPH21_RS08340	PF02817	e3 binding domain
SPH21_RS08360	PF00127	Copper binding proteins, plastocyanin/azurin family
SPH21_RS08365	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS08365	PF02852	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
SPH21_RS08375	PF00884	Sulfatase
SPH21_RS08380	PF00884	Sulfatase
SPH21_RS08385	PF12823	Domain of unknown function (DUF3817)
SPH21_RS08390	PF00873	AcrB/AcrD/AcrF family
SPH21_RS08395	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
SPH21_RS08410	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS08415	PF02873	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
SPH21_RS08415	PF01565	FAD binding domain 
SPH21_RS08420	PF08281	Sigma-70, region 4
SPH21_RS08420	PF04542	Sigma-70 region 2 
SPH21_RS08445	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS08450	PF03129	Anticodon binding domain
SPH21_RS08455	PF03009	Glycerophosphoryl diester phosphodiesterase family
SPH21_RS08460	PF00005	ABC transporter
SPH21_RS08475	PF13336	Acetyl-CoA hydrolase/transferase C-terminal domain
SPH21_RS08475	PF02550	Acetyl-CoA hydrolase/transferase N-terminal domain
SPH21_RS08485	PF02767	DNA polymerase III beta subunit, central domain
SPH21_RS08485	PF00712	DNA polymerase III beta subunit, N-terminal domain
SPH21_RS08485	PF02768	DNA polymerase III beta subunit, C-terminal domain
SPH21_RS08490	PF09335	SNARE associated Golgi protein
SPH21_RS08495	PF00297	Ribosomal protein L3
SPH21_RS08500	PF00573	Ribosomal protein L4/L1 family
SPH21_RS08505	PF00276	Ribosomal protein L23
SPH21_RS08510	PF00181	Ribosomal Proteins L2, RNA binding domain
SPH21_RS08510	PF03947	Ribosomal Proteins L2, C-terminal domain
SPH21_RS08515	PF00203	Ribosomal protein S19
SPH21_RS08520	PF00237	Ribosomal protein L22p/L17e
SPH21_RS08525	PF07650	KH domain
SPH21_RS08525	PF00189	Ribosomal protein S3, C-terminal domain
SPH21_RS08530	PF00252	Ribosomal protein L16p/L10e
SPH21_RS08535	PF00831	Ribosomal L29 protein
SPH21_RS08540	PF00366	Ribosomal protein S17
SPH21_RS08545	PF00238	Ribosomal protein L14p/L23e
SPH21_RS08550	PF17136	Ribosomal proteins 50S L24/mitochondrial 39S L24
SPH21_RS08550	PF00467	KOW motif
SPH21_RS08555	PF00281	Ribosomal protein L5
SPH21_RS08555	PF00673	ribosomal L5P family C-terminus
SPH21_RS08560	PF00253	Ribosomal protein S14p/S29e
SPH21_RS08565	PF00410	Ribosomal protein S8
SPH21_RS08570	PF00347	Ribosomal protein L6
SPH21_RS08575	PF00861	Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
SPH21_RS08580	PF00333	Ribosomal protein S5, N-terminal domain
SPH21_RS08580	PF03719	Ribosomal protein S5, C-terminal domain
SPH21_RS08585	PF00327	Ribosomal protein L30p/L7e
SPH21_RS08590	PF00828	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
SPH21_RS08595	PF00344	SecY translocase
SPH21_RS08600	PF00557	Metallopeptidase family M24
SPH21_RS08605	PF01176	Translation initiation factor 1A / IF-1
SPH21_RS08610	PF00416	Ribosomal protein S13/S18
SPH21_RS08615	PF00411	Ribosomal protein S11
SPH21_RS08620	PF00163	Ribosomal protein S4/S9 N-terminal domain
SPH21_RS08620	PF01479	S4 domain
SPH21_RS08625	PF01000	RNA polymerase Rpb3/RpoA insert domain
SPH21_RS08625	PF03118	Bacterial RNA polymerase, alpha chain C terminal domain
SPH21_RS08625	PF01193	RNA polymerase Rpb3/Rpb11 dimerisation domain
SPH21_RS08630	PF01196	Ribosomal protein L17
SPH21_RS08640	PF00012	Hsp70 protein
SPH21_RS08645	PF13419	Haloacid dehalogenase-like hydrolase
SPH21_RS08655	PF01565	FAD binding domain 
SPH21_RS08655	PF02913	FAD linked oxidases, C-terminal domain
SPH21_RS08660	PF00930	Dipeptidyl peptidase IV (DPP IV) N-terminal region
SPH21_RS08660	PF07676	WD40-like Beta Propeller Repeat
SPH21_RS08660	PF00326	Prolyl oligopeptidase family
SPH21_RS08670	PF05872	Bacterial protein of unknown function (DUF853)
SPH21_RS08680	PF00483	Nucleotidyl transferase
SPH21_RS08685	PF16363	GDP-mannose 4,6 dehydratase
SPH21_RS08690	PF16353	Domain of unknown function(DUF4981)
SPH21_RS08690	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS08690	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS08690	PF02929	Beta galactosidase small chain
SPH21_RS08690	PF00703	Glycosyl hydrolases family 2
SPH21_RS08705	PF13533	Biotin-lipoyl like
SPH21_RS08720	PF02441	Flavoprotein
SPH21_RS08720	PF04127	DNA / pantothenate metabolism flavoprotein
SPH21_RS08735	PF00583	Acetyltransferase (GNAT) family
SPH21_RS08750	PF05506	Domain of unknown function (DUF756)
SPH21_RS08750	PF04185	Phosphoesterase family
SPH21_RS08765	PF00593	TonB dependent receptor
SPH21_RS08765	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS08780	PF07980	SusD family
SPH21_RS08780	PF14322	Starch-binding associating with outer membrane
SPH21_RS08785	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS08785	PF00593	TonB dependent receptor
SPH21_RS08810	PF00953	Glycosyl transferase family 4
SPH21_RS08850	PF00535	Glycosyl transferase family 2
SPH21_RS08855	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS08895	PF00535	Glycosyl transferase family 2
SPH21_RS08905	PF00535	Glycosyl transferase family 2
SPH21_RS08915	PF00534	Glycosyl transferases group 1
SPH21_RS08915	PF13439	Glycosyltransferase Family 4
SPH21_RS08920	PF12464	Maltose acetyltransferase 
SPH21_RS08920	PF14602	Hexapeptide repeat of succinyl-transferase
SPH21_RS08920	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS08955	PF13614	AAA domain
SPH21_RS08955	PF02706	Chain length determinant protein
SPH21_RS08955	PF13807	G-rich domain on putative tyrosine kinase
SPH21_RS08960	PF03721	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
SPH21_RS08960	PF00984	UDP-glucose/GDP-mannose dehydrogenase family, central domain
SPH21_RS08960	PF03720	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain
SPH21_RS08965	PF02719	Polysaccharide biosynthesis protein
SPH21_RS08970	PF01041	DegT/DnrJ/EryC1/StrS aminotransferase family
SPH21_RS08980	PF08666	SAF domain
SPH21_RS08980	PF03102	NeuB family
SPH21_RS08985	PF02350	UDP-N-acetylglucosamine 2-epimerase
SPH21_RS08990	PF00483	Nucleotidyl transferase
SPH21_RS08995	PF13472	GDSL-like Lipase/Acylhydrolase family
SPH21_RS08995	PF02348	Cytidylyltransferase
SPH21_RS09030	PF13439	Glycosyltransferase Family 4
SPH21_RS09030	PF00534	Glycosyl transferases group 1
SPH21_RS09045	PF02350	UDP-N-acetylglucosamine 2-epimerase
SPH21_RS09055	PF01370	NAD dependent epimerase/dehydratase family
SPH21_RS09060	PF02698	DUF218 domain
SPH21_RS09070	PF02719	Polysaccharide biosynthesis protein
SPH21_RS09090	PF01850	PIN domain
SPH21_RS09100	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS09105	PF02566	OsmC-like protein
SPH21_RS09110	PF07859	alpha/beta hydrolase fold
SPH21_RS09145	PF08534	Redoxin
SPH21_RS09150	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09150	PF00593	TonB dependent receptor
SPH21_RS09155	PF07980	SusD family
SPH21_RS09155	PF14322	Starch-binding associating with outer membrane
SPH21_RS09185	PF04397	LytTr DNA-binding domain
SPH21_RS09185	PF00072	Response regulator receiver domain
SPH21_RS09195	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS09195	PF01548	Transposase
SPH21_RS09250	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09250	PF00593	TonB dependent receptor
SPH21_RS09290	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09290	PF00593	TonB dependent receptor
SPH21_RS09300	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS09300	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS09300	PF07494	Two component regulator propeller
SPH21_RS09300	PF00072	Response regulator receiver domain
SPH21_RS09300	PF07495	Y_Y_Y domain
SPH21_RS09300	PF12833	Helix-turn-helix domain
SPH21_RS09305	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09305	PF00593	TonB dependent receptor
SPH21_RS09325	PF07980	SusD family
SPH21_RS09325	PF14322	Starch-binding associating with outer membrane
SPH21_RS09330	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09330	PF00593	TonB dependent receptor
SPH21_RS09365	PF00664	ABC transporter transmembrane region
SPH21_RS09365	PF00005	ABC transporter
SPH21_RS09365	PF03412	Peptidase C39 family
SPH21_RS09385	PF07980	SusD family
SPH21_RS09390	PF00593	TonB dependent receptor
SPH21_RS09390	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09410	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09410	PF00593	TonB dependent receptor
SPH21_RS09425	PF01663	Type I phosphodiesterase / nucleotide pyrophosphatase
SPH21_RS09430	PF00703	Glycosyl hydrolases family 2
SPH21_RS09430	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS09430	PF18368	Exo-beta-D-glucosaminidase Ig-fold domain
SPH21_RS09435	PF12833	Helix-turn-helix domain
SPH21_RS09445	PF02554	Carbon starvation protein CstA
SPH21_RS09445	PF13722	5TM C-terminal transporter carbon starvation CstA
SPH21_RS09455	PF00115	Cytochrome C and Quinol oxidase polypeptide I
SPH21_RS09460	PF00126	Bacterial regulatory helix-turn-helix protein, lysR family
SPH21_RS09460	PF03466	LysR substrate binding domain
SPH21_RS09465	PF01053	Cys/Met metabolism PLP-dependent enzyme
SPH21_RS09470	PF01979	Amidohydrolase family
SPH21_RS09485	PF00593	TonB dependent receptor
SPH21_RS09485	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09490	PF14322	Starch-binding associating with outer membrane
SPH21_RS09490	PF07980	SusD family
SPH21_RS09505	PF12796	Ankyrin repeats (3 copies)
SPH21_RS09510	PF07969	Amidohydrolase family
SPH21_RS09525	PF00593	TonB dependent receptor
SPH21_RS09525	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09530	PF07980	SusD family
SPH21_RS09530	PF14322	Starch-binding associating with outer membrane
SPH21_RS09545	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09545	PF00593	TonB dependent receptor
SPH21_RS09560	PF04397	LytTr DNA-binding domain
SPH21_RS09560	PF00072	Response regulator receiver domain
SPH21_RS09585	PF16363	GDP-mannose 4,6 dehydratase
SPH21_RS09590	PF03062	MBOAT, membrane-bound O-acyltransferase family
SPH21_RS09615	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS09640	PF13439	Glycosyltransferase Family 4
SPH21_RS09640	PF00534	Glycosyl transferases group 1
SPH21_RS09650	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS09655	PF00535	Glycosyl transferase family 2
SPH21_RS09660	PF13579	Glycosyl transferase 4-like domain
SPH21_RS09660	PF00534	Glycosyl transferases group 1
SPH21_RS09675	PF13614	AAA domain
SPH21_RS09675	PF02706	Chain length determinant protein
SPH21_RS09675	PF13807	G-rich domain on putative tyrosine kinase
SPH21_RS09680	PF03720	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain
SPH21_RS09680	PF03721	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
SPH21_RS09680	PF00984	UDP-glucose/GDP-mannose dehydrogenase family, central domain
SPH21_RS09695	PF13419	Haloacid dehalogenase-like hydrolase
SPH21_RS09710	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09710	PF00593	TonB dependent receptor
SPH21_RS09715	PF14322	Starch-binding associating with outer membrane
SPH21_RS09715	PF07980	SusD family
SPH21_RS09735	PF00593	TonB dependent receptor
SPH21_RS09735	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09750	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS09750	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS09750	PF00703	Glycosyl hydrolases family 2
SPH21_RS09750	PF18565	Glycoside hydrolase family 2 C-terminal domain 5
SPH21_RS09750	PF16355	Domain of unknown function (DUF4982)
SPH21_RS09755	PF07980	SusD family
SPH21_RS09755	PF14322	Starch-binding associating with outer membrane
SPH21_RS09760	PF00593	TonB dependent receptor
SPH21_RS09760	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09765	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS09765	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS09765	PF07494	Two component regulator propeller
SPH21_RS09765	PF07495	Y_Y_Y domain
SPH21_RS09765	PF00072	Response regulator receiver domain
SPH21_RS09765	PF12833	Helix-turn-helix domain
SPH21_RS09785	PF01263	Aldose 1-epimerase
SPH21_RS09805	PF01479	S4 domain
SPH21_RS09805	PF00849	RNA pseudouridylate synthase
SPH21_RS09825	PF00593	TonB dependent receptor
SPH21_RS09825	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS09830	PF07980	SusD family
SPH21_RS09830	PF14322	Starch-binding associating with outer membrane
SPH21_RS09870	PF04408	Helicase associated domain (HA2)
SPH21_RS09870	PF00270	DEAD/DEAH box helicase
SPH21_RS09870	PF08482	ATP-dependent helicase C-terminal
SPH21_RS09870	PF00271	Helicase conserved C-terminal domain
SPH21_RS09875	PF07786	Protein of unknown function (DUF1624)
SPH21_RS09875	PF04235	Protein of unknown function (DUF418)
SPH21_RS09890	PF00483	Nucleotidyl transferase
SPH21_RS09890	PF01050	Mannose-6-phosphate isomerase
SPH21_RS09900	PF03721	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
SPH21_RS09900	PF00984	UDP-glucose/GDP-mannose dehydrogenase family, central domain
SPH21_RS09900	PF03720	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain
SPH21_RS09905	PF00072	Response regulator receiver domain
SPH21_RS09905	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS09935	PF01370	NAD dependent epimerase/dehydratase family
SPH21_RS09965	PF00408	Phosphoglucomutase/phosphomannomutase, C-terminal domain
SPH21_RS09965	PF02878	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
SPH21_RS09965	PF02879	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
SPH21_RS09965	PF02880	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
SPH21_RS09985	PF00535	Glycosyl transferase family 2
SPH21_RS09990	PF01041	DegT/DnrJ/EryC1/StrS aminotransferase family
SPH21_RS10005	PF02706	Chain length determinant protein
SPH21_RS10005	PF13614	AAA domain
SPH21_RS10005	PF13807	G-rich domain on putative tyrosine kinase
SPH21_RS10020	PF00534	Glycosyl transferases group 1
SPH21_RS10025	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS10035	PF00534	Glycosyl transferases group 1
SPH21_RS10045	PF02397	Bacterial sugar transferase
SPH21_RS10055	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS10055	PF00072	Response regulator receiver domain
SPH21_RS10070	PF02954	Bacterial regulatory protein, Fis family
SPH21_RS10070	PF00072	Response regulator receiver domain
SPH21_RS10070	PF00158	Sigma-54 interaction domain
SPH21_RS10080	PF00899	ThiF family
SPH21_RS10090	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS10090	PF00989	PAS fold
SPH21_RS10090	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS10095	PF00072	Response regulator receiver domain
SPH21_RS10095	PF02954	Bacterial regulatory protein, Fis family
SPH21_RS10095	PF00158	Sigma-54 interaction domain
SPH21_RS10100	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS10105	PF01609	Transposase DDE domain
SPH21_RS10120	PF00072	Response regulator receiver domain
SPH21_RS10120	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS10125	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS10125	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS10130	PF00593	TonB dependent receptor
SPH21_RS10130	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS10145	PF17678	Glycosyl hydrolase family 92 N-terminal domain
SPH21_RS10145	PF07971	Glycosyl hydrolase family 92
SPH21_RS10155	PF17678	Glycosyl hydrolase family 92 N-terminal domain
SPH21_RS10155	PF07971	Glycosyl hydrolase family 92
SPH21_RS10165	PF07689	KaiB domain
SPH21_RS10165	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS10165	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS10175	PF01380	SIS domain
SPH21_RS10185	PF02397	Bacterial sugar transferase
SPH21_RS10190	PF00535	Glycosyl transferase family 2
SPH21_RS10200	PF13439	Glycosyltransferase Family 4
SPH21_RS10200	PF00534	Glycosyl transferases group 1
SPH21_RS10220	PF00535	Glycosyl transferase family 2
SPH21_RS10235	PF02416	mttA/Hcf106 family
SPH21_RS10240	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS10240	PF09456	RcsC Alpha-Beta-Loop (ABL)
SPH21_RS10240	PF00072	Response regulator receiver domain
SPH21_RS10240	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS10245	PF08545	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
SPH21_RS10245	PF08541	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal  
SPH21_RS10250	PF01544	CorA-like Mg2+ transporter protein
SPH21_RS10265	PF04321	RmlD substrate binding domain
SPH21_RS10270	PF00293	NUDIX domain
SPH21_RS10280	PF02347	Glycine cleavage system P-protein
SPH21_RS10285	PF00207	Alpha-2-macroglobulin family
SPH21_RS10285	PF07703	Alpha-2-macroglobulin bait region domain
SPH21_RS10285	PF01835	MG2 domain
SPH21_RS10290	PF03949	Malic enzyme, NAD binding domain
SPH21_RS10290	PF01515	Phosphate acetyl/butaryl transferase
SPH21_RS10290	PF00390	Malic enzyme, N-terminal domain
SPH21_RS10295	PF07499	RuvA, C-terminal domain
SPH21_RS10295	PF01330	RuvA N terminal domain
SPH21_RS10305	PF09134	Invasin, domain 3
SPH21_RS10305	PF11924	Inverse autotransporter, beta-domain
SPH21_RS10305	PF02369	Bacterial Ig-like domain (group 1)
SPH21_RS10315	PF00691	OmpA family
SPH21_RS10320	PF00072	Response regulator receiver domain
SPH21_RS10320	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS10330	PF00072	Response regulator receiver domain
SPH21_RS10330	PF01339	CheB methylesterase
SPH21_RS10335	PF07694	5TMR of 5TMR-LYT
SPH21_RS10335	PF06580	Histidine kinase
SPH21_RS10340	PF04397	LytTr DNA-binding domain
SPH21_RS10340	PF00072	Response regulator receiver domain
SPH21_RS10370	PF00216	Bacterial DNA-binding protein
SPH21_RS10385	PF00293	NUDIX domain
SPH21_RS10395	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS10395	PF00072	Response regulator receiver domain
SPH21_RS10400	PF03631	Virulence factor BrkB
SPH21_RS10410	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS10410	PF00593	TonB dependent receptor
SPH21_RS10425	PF11965	Domain of unknown function (DUF3479)
SPH21_RS10425	PF02514	CobN/Magnesium Chelatase
SPH21_RS10445	PF04041	beta-1,4-mannooligosaccharide phosphorylase
SPH21_RS10470	PF08541	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal  
SPH21_RS10470	PF08545	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
SPH21_RS10475	PF00313	'Cold-shock' DNA-binding domain
SPH21_RS10485	PF01638	HxlR-like helix-turn-helix
SPH21_RS10495	PF00484	Carbonic anhydrase
SPH21_RS10505	PF08281	Sigma-70, region 4
SPH21_RS10505	PF04542	Sigma-70 region 2 
SPH21_RS10540	PF01594	AI-2E family transporter
SPH21_RS10545	PF05532	CsbD-like
SPH21_RS10575	PF00072	Response regulator receiver domain
SPH21_RS10575	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS10590	PF13442	Cytochrome C oxidase, cbb3-type, subunit III 
SPH21_RS10595	PF00857	Isochorismatase family
SPH21_RS10615	PF08448	PAS fold
SPH21_RS10615	PF01739	CheR methyltransferase, SAM binding domain
SPH21_RS10615	PF01339	CheB methylesterase
SPH21_RS10615	PF03705	CheR methyltransferase, all-alpha domain
SPH21_RS10620	PF01590	GAF domain
SPH21_RS10620	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS10620	PF00360	Phytochrome region
SPH21_RS10620	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS10620	PF08446	PAS fold
SPH21_RS10640	PF00016	Ribulose bisphosphate carboxylase large chain, catalytic domain
SPH21_RS10640	PF02788	Ribulose bisphosphate carboxylase large chain, N-terminal domain
SPH21_RS10645	PF07005	Sugar-binding N-terminal domain
SPH21_RS10645	PF17042	Nucleotide-binding C-terminal domain
SPH21_RS10650	PF01177	Asp/Glu/Hydantoin racemase
SPH21_RS10655	PF01758	Sodium Bile acid symporter family
SPH21_RS10660	PF04616	Glycosyl hydrolases family 43
SPH21_RS10670	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS10670	PF00072	Response regulator receiver domain
SPH21_RS10695	PF04239	Protein of unknown function (DUF421)
SPH21_RS10700	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS10700	PF00072	Response regulator receiver domain
SPH21_RS10710	PF00106	short chain dehydrogenase
SPH21_RS10710	PF00561	alpha/beta hydrolase fold
SPH21_RS10725	PF02922	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
SPH21_RS10725	PF02806	Alpha amylase, C-terminal all-beta domain
SPH21_RS10725	PF00128	Alpha amylase, catalytic domain
SPH21_RS10730	PF16657	Maltogenic Amylase, C-terminal domain
SPH21_RS10730	PF00128	Alpha amylase, catalytic domain
SPH21_RS10735	PF11896	Domain of unknown function (DUF3416)
SPH21_RS10735	PF00128	Alpha amylase, catalytic domain
SPH21_RS10740	PF17676	LD-carboxypeptidase C-terminal domain
SPH21_RS10740	PF02016	LD-carboxypeptidase N-terminal domain
SPH21_RS10750	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS10770	PF05067	Manganese containing catalase
SPH21_RS10775	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS10775	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS10775	PF00989	PAS fold
SPH21_RS10775	PF16736	Single Cache-like 
SPH21_RS10780	PF02779	Transketolase, pyrimidine binding domain
SPH21_RS10780	PF02780	Transketolase, C-terminal domain
SPH21_RS10780	PF00456	Transketolase, thiamine diphosphate binding domain
SPH21_RS10785	PF00923	Transaldolase/Fructose-6-phosphate aldolase
SPH21_RS10810	PF01597	Glycine cleavage H-protein
SPH21_RS10825	PF07664	Ferrous iron transport protein B C terminus
SPH21_RS10825	PF07670	Nucleoside recognition
SPH21_RS10825	PF02421	Ferrous iron transport protein B
SPH21_RS10840	PF04337	Protein of unknown function, DUF480
SPH21_RS10845	PF04551	GcpE protein
SPH21_RS10850	PF02776	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
SPH21_RS10850	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
SPH21_RS10850	PF00205	Thiamine pyrophosphate enzyme, central domain
SPH21_RS10855	PF00146	NADH dehydrogenase
SPH21_RS10860	PF12838	4Fe-4S dicluster domain
SPH21_RS10865	PF00499	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
SPH21_RS10870	PF00420	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
SPH21_RS10875	PF00361	Proton-conducting membrane transporter
SPH21_RS10875	PF00662	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
SPH21_RS10875	PF01010	NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus
SPH21_RS10880	PF00361	Proton-conducting membrane transporter
SPH21_RS10880	PF01059	NADH-ubiquinone oxidoreductase chain 4, amino terminus
SPH21_RS10885	PF00361	Proton-conducting membrane transporter
SPH21_RS10890	PF00909	Ammonium Transporter Family
SPH21_RS10895	PF00156	Phosphoribosyl transferase domain
SPH21_RS10910	PF01209	ubiE/COQ5 methyltransferase family
SPH21_RS10915	PF01977	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
SPH21_RS10925	PF00210	Ferritin-like domain
SPH21_RS10940	PF02875	Mur ligase family, glutamate ligase domain
SPH21_RS10940	PF08245	Mur ligase middle domain
SPH21_RS10955	PF01618	MotA/TolQ/ExbB proton channel family
SPH21_RS10975	PF00185	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
SPH21_RS10975	PF02729	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
SPH21_RS10980	PF00156	Phosphoribosyl transferase domain
SPH21_RS10995	PF04228	Putative neutral zinc metallopeptidase
SPH21_RS11010	PF00694	Aconitase C-terminal domain
SPH21_RS11010	PF00330	Aconitase family (aconitate hydratase)
SPH21_RS11015	PF03255	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
SPH21_RS11025	PF00958	GMP synthase C terminal domain
SPH21_RS11025	PF00117	Glutamine amidotransferase class-I
SPH21_RS11025	PF02540	NAD synthase
SPH21_RS11035	PF01029	NusB family
SPH21_RS11035	PF01189	16S rRNA methyltransferase RsmB/F
SPH21_RS11040	PF00999	Sodium/hydrogen exchanger family
SPH21_RS11045	PF01914	MarC family integral membrane protein
SPH21_RS11050	PF13520	Amino acid permease
SPH21_RS11055	PF03030	Inorganic H+ pyrophosphatase
SPH21_RS11060	PF13520	Amino acid permease
SPH21_RS11070	PF00156	Phosphoribosyl transferase domain
SPH21_RS11080	PF02771	Acyl-CoA dehydrogenase, N-terminal domain
SPH21_RS11080	PF02770	Acyl-CoA dehydrogenase, middle domain
SPH21_RS11080	PF00441	Acyl-CoA dehydrogenase, C-terminal domain
SPH21_RS11085	PF06039	Malate:quinone oxidoreductase (Mqo)
SPH21_RS11090	PF00480	ROK family
SPH21_RS11115	PF08448	PAS fold
SPH21_RS11115	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS11115	PF08447	PAS fold
SPH21_RS11120	PF00072	Response regulator receiver domain
SPH21_RS11120	PF01966	HD domain
SPH21_RS11125	PF00672	HAMP domain
SPH21_RS11125	PF00211	Adenylate and Guanylate cyclase catalytic domain
SPH21_RS11130	PF10035	Uncharacterized protein conserved in bacteria (DUF2179)
SPH21_RS11130	PF02588	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SPH21_RS11160	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS11160	PF00593	TonB dependent receptor
SPH21_RS11180	PF12833	Helix-turn-helix domain
SPH21_RS11180	PF02311	AraC-like ligand binding domain
SPH21_RS11200	PF01619	Proline dehydrogenase
SPH21_RS11210	PF01761	3-dehydroquinate synthase
SPH21_RS11220	PF00585	C-terminal regulatory domain of Threonine dehydratase
SPH21_RS11220	PF00291	Pyridoxal-phosphate dependent enzyme
SPH21_RS11225	PF00180	Isocitrate/isopropylmalate dehydrogenase
SPH21_RS11230	PF00682	HMGL-like
SPH21_RS11230	PF08502	LeuA allosteric (dimerisation) domain
SPH21_RS11235	PF00694	Aconitase C-terminal domain
SPH21_RS11240	PF00330	Aconitase family (aconitate hydratase)
SPH21_RS11245	PF08502	LeuA allosteric (dimerisation) domain
SPH21_RS11245	PF00682	HMGL-like
SPH21_RS11250	PF00005	ABC transporter
SPH21_RS11255	PF07991	Acetohydroxy acid isomeroreductase, NADPH-binding domain
SPH21_RS11255	PF01450	Acetohydroxy acid isomeroreductase, catalytic domain
SPH21_RS11275	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
SPH21_RS11275	PF02776	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
SPH21_RS11275	PF00205	Thiamine pyrophosphate enzyme, central domain
SPH21_RS11280	PF00920	Dehydratase family
SPH21_RS11285	PF02823	ATP synthase, Delta/Epsilon chain, beta-sandwich domain
SPH21_RS11290	PF02874	ATP synthase alpha/beta family, beta-barrel domain
SPH21_RS11290	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain
SPH21_RS11300	PF04321	RmlD substrate binding domain
SPH21_RS11310	PF00912	Transglycosylase
SPH21_RS11320	PF01479	S4 domain
SPH21_RS11320	PF00849	RNA pseudouridylate synthase
SPH21_RS11325	PF12127	SigmaW regulon antibacterial
SPH21_RS11330	PF00474	Sodium:solute symporter family
SPH21_RS11335	PF00701	Dihydrodipicolinate synthetase family
SPH21_RS11345	PF00295	Glycosyl hydrolases family 28
SPH21_RS11355	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS11355	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS11355	PF00703	Glycosyl hydrolases family 2
SPH21_RS11355	PF16355	Domain of unknown function (DUF4982)
SPH21_RS11365	PF00593	TonB dependent receptor
SPH21_RS11365	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS11370	PF07980	SusD family
SPH21_RS11370	PF14322	Starch-binding associating with outer membrane
SPH21_RS11405	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS11405	PF16355	Domain of unknown function (DUF4982)
SPH21_RS11405	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS11405	PF00703	Glycosyl hydrolases family 2
SPH21_RS11410	PF05592	Bacterial alpha-L-rhamnosidase concanavalin-like domain
SPH21_RS11410	PF17389	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
SPH21_RS11410	PF08531	Alpha-L-rhamnosidase N-terminal domain
SPH21_RS11410	PF17390	Bacterial alpha-L-rhamnosidase C-terminal domain
SPH21_RS11465	PF05592	Bacterial alpha-L-rhamnosidase concanavalin-like domain
SPH21_RS11465	PF17389	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
SPH21_RS11465	PF17390	Bacterial alpha-L-rhamnosidase C-terminal domain
SPH21_RS11465	PF08531	Alpha-L-rhamnosidase N-terminal domain
SPH21_RS11475	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS11475	PF16355	Domain of unknown function (DUF4982)
SPH21_RS11475	PF00703	Glycosyl hydrolases family 2
SPH21_RS11475	PF18565	Glycoside hydrolase family 2 C-terminal domain 5
SPH21_RS11475	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS11490	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS11490	PF00593	TonB dependent receptor
SPH21_RS11495	PF07980	SusD family
SPH21_RS11495	PF14322	Starch-binding associating with outer membrane
SPH21_RS11515	PF00474	Sodium:solute symporter family
SPH21_RS11525	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS11525	PF01548	Transposase
SPH21_RS11535	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS11535	PF16353	Domain of unknown function(DUF4981)
SPH21_RS11535	PF02929	Beta galactosidase small chain
SPH21_RS11535	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS11535	PF00703	Glycosyl hydrolases family 2
SPH21_RS11545	PF02515	CoA-transferase family III
SPH21_RS11550	PF02515	CoA-transferase family III
SPH21_RS11570	PF07690	Major Facilitator Superfamily
SPH21_RS11575	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS11580	PF07944	Beta-L-arabinofuranosidase, GH127
SPH21_RS11595	PF03948	Ribosomal protein L9, C-terminal domain
SPH21_RS11595	PF01281	Ribosomal protein L9, N-terminal domain
SPH21_RS11600	PF01084	Ribosomal protein S18
SPH21_RS11605	PF01250	Ribosomal protein S6
SPH21_RS11610	PF12169	DNA polymerase III subunits gamma and tau domain III
SPH21_RS11625	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS11625	PF00593	TonB dependent receptor
SPH21_RS11630	PF07980	SusD family
SPH21_RS11630	PF14322	Starch-binding associating with outer membrane
SPH21_RS11640	PF13488	Glycine zipper
SPH21_RS11640	PF00691	OmpA family
SPH21_RS11645	PF13183	4Fe-4S dicluster domain
SPH21_RS11645	PF02754	Cysteine-rich domain
SPH21_RS11650	PF02754	Cysteine-rich domain
SPH21_RS11650	PF13183	4Fe-4S dicluster domain
SPH21_RS11650	PF02665	Nitrate reductase gamma subunit
SPH21_RS11655	PF00326	Prolyl oligopeptidase family
SPH21_RS11655	PF07676	WD40-like Beta Propeller Repeat
SPH21_RS11665	PF00293	NUDIX domain
SPH21_RS11670	PF01252	Signal peptidase (SPase) II
SPH21_RS11680	PF01638	HxlR-like helix-turn-helix
SPH21_RS11685	PF01566	Natural resistance-associated macrophage protein
SPH21_RS11695	PF04170	NlpE N-terminal domain
SPH21_RS11695	PF17185	NlpE C-terminal OB domain
SPH21_RS11705	PF07980	SusD family
SPH21_RS11705	PF14322	Starch-binding associating with outer membrane
SPH21_RS11710	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS11710	PF00593	TonB dependent receptor
SPH21_RS11715	PF00265	Thymidine kinase
SPH21_RS11725	PF01098	Cell cycle protein
SPH21_RS11730	PF03717	Penicillin-binding Protein dimerisation domain
SPH21_RS11730	PF00905	Penicillin binding protein transpeptidase domain
SPH21_RS11760	PF02142	MGS-like domain
SPH21_RS11760	PF01808	AICARFT/IMPCHase bienzyme
SPH21_RS11770	PF00551	Formyl transferase
SPH21_RS11775	PF00144	Beta-lactamase
SPH21_RS11780	PF04397	LytTr DNA-binding domain
SPH21_RS11780	PF00072	Response regulator receiver domain
SPH21_RS11785	PF13492	GAF domain
SPH21_RS11785	PF07694	5TMR of 5TMR-LYT
SPH21_RS11785	PF06580	Histidine kinase
SPH21_RS11785	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS11805	PF00083	Sugar (and other) transporter
SPH21_RS11820	PF01165	Ribosomal protein S21
SPH21_RS11835	PF02899	Phage integrase, N-terminal SAM-like domain
SPH21_RS11835	PF00589	Phage integrase family
SPH21_RS11865	PF03144	Elongation factor Tu domain 2
SPH21_RS11865	PF03143	Elongation factor Tu C-terminal domain
SPH21_RS11865	PF00009	Elongation factor Tu GTP binding domain
SPH21_RS11880	PF02357	Transcription termination factor nusG
SPH21_RS11880	PF00467	KOW motif
SPH21_RS11885	PF00298	Ribosomal protein L11, RNA binding domain
SPH21_RS11885	PF03946	Ribosomal protein L11, N-terminal domain
SPH21_RS11890	PF00687	Ribosomal protein L1p/L10e family
SPH21_RS11895	PF00466	Ribosomal protein L10
SPH21_RS11900	PF00542	Ribosomal protein L7/L12 C-terminal domain
SPH21_RS11900	PF16320	Ribosomal protein L7/L12 dimerisation domain
SPH21_RS11905	PF04565	RNA polymerase Rpb2, domain 3
SPH21_RS11905	PF10385	RNA polymerase beta subunit external 1 domain
SPH21_RS11905	PF04563	RNA polymerase beta subunit
SPH21_RS11905	PF04560	RNA polymerase Rpb2, domain 7
SPH21_RS11905	PF00562	RNA polymerase Rpb2, domain 6
SPH21_RS11905	PF04561	RNA polymerase Rpb2, domain 2
SPH21_RS11910	PF00623	RNA polymerase Rpb1, domain 2
SPH21_RS11910	PF04998	RNA polymerase Rpb1, domain 5
SPH21_RS11910	PF04997	RNA polymerase Rpb1, domain 1
SPH21_RS11910	PF05000	RNA polymerase Rpb1, domain 4
SPH21_RS11910	PF04983	RNA polymerase Rpb1, domain 3
SPH21_RS11925	PF00152	tRNA synthetases class II (D, K and N) 
SPH21_RS11925	PF14229	Domain of unknown function (DUF4332)
SPH21_RS11925	PF01336	OB-fold nucleic acid binding domain
SPH21_RS11930	PF08281	Sigma-70, region 4
SPH21_RS11930	PF04542	Sigma-70 region 2 
SPH21_RS11945	PF04972	BON domain
SPH21_RS11945	PF00691	OmpA family
SPH21_RS11955	PF01416	tRNA pseudouridine synthase
SPH21_RS11960	PF00005	ABC transporter
SPH21_RS11960	PF00664	ABC transporter transmembrane region
SPH21_RS11965	PF02629	CoA binding domain
SPH21_RS11965	PF00549	CoA-ligase
SPH21_RS11970	PF01641	SelR domain
SPH21_RS11975	PF07971	Glycosyl hydrolase family 92
SPH21_RS11975	PF17678	Glycosyl hydrolase family 92 N-terminal domain
SPH21_RS12000	PF02272	DHHA1 domain
SPH21_RS12000	PF01368	DHH family
SPH21_RS12000	PF01743	Poly A polymerase head domain
SPH21_RS12000	PF00571	CBS domain
SPH21_RS12005	PF01300	Telomere recombination
SPH21_RS12010	PF00534	Glycosyl transferases group 1
SPH21_RS12015	PF14602	Hexapeptide repeat of succinyl-transferase
SPH21_RS12015	PF14805	Tetrahydrodipicolinate N-succinyltransferase N-terminal
SPH21_RS12015	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS12030	PF01569	PAP2 superfamily
SPH21_RS12035	PF01479	S4 domain
SPH21_RS12040	PF00535	Glycosyl transferase family 2
SPH21_RS12065	PF00535	Glycosyl transferase family 2
SPH21_RS12095	PF00691	OmpA family
SPH21_RS12095	PF13677	Membrane MotB of proton-channel complex MotA/MotB 
SPH21_RS12105	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS12105	PF00593	TonB dependent receptor
SPH21_RS12110	PF12796	Ankyrin repeats (3 copies)
SPH21_RS12130	PF08338	Domain of unknown function (DUF1731)
SPH21_RS12130	PF01370	NAD dependent epimerase/dehydratase family
SPH21_RS12135	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS12135	PF08361	MAATS-type transcriptional repressor, C-terminal region
SPH21_RS12170	PF01751	Toprim domain
SPH21_RS12170	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS12170	PF00986	DNA gyrase B subunit, carboxyl terminus
SPH21_RS12170	PF00204	DNA gyrase B
SPH21_RS12180	PF00133	tRNA synthetases class I (I, L, M and V)
SPH21_RS12180	PF08264	Anticodon-binding domain of tRNA
SPH21_RS12180	PF10458	Valyl tRNA synthetase tRNA binding arm
SPH21_RS12205	PF12848	ABC transporter
SPH21_RS12205	PF00005	ABC transporter
SPH21_RS12215	PF00795	Carbon-nitrogen hydrolase
SPH21_RS12215	PF00583	Acetyltransferase (GNAT) family
SPH21_RS12220	PF17864	RuvB AAA lid domain
SPH21_RS12220	PF05491	RuvB C-terminal winged helix domain
SPH21_RS12220	PF05496	Holliday junction DNA helicase RuvB P-loop domain
SPH21_RS12225	PF00535	Glycosyl transferase family 2
SPH21_RS12230	PF00854	POT family
SPH21_RS12240	PF00326	Prolyl oligopeptidase family
SPH21_RS12240	PF00930	Dipeptidyl peptidase IV (DPP IV) N-terminal region
SPH21_RS12250	PF02803	Thiolase, C-terminal domain
SPH21_RS12250	PF00108	Thiolase, N-terminal domain
SPH21_RS12265	PF01966	HD domain
SPH21_RS12265	PF07698	7TM receptor with intracellular HD hydrolase
SPH21_RS12265	PF07697	7TM-HD extracellular
SPH21_RS12280	PF16363	GDP-mannose 4,6 dehydratase
SPH21_RS12305	PF06123	Inner membrane protein CreD
SPH21_RS12315	PF00593	TonB dependent receptor
SPH21_RS12315	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS12320	PF01638	HxlR-like helix-turn-helix
SPH21_RS12325	PF02525	Flavodoxin-like fold
SPH21_RS12350	PF04542	Sigma-70 region 2 
SPH21_RS12350	PF08281	Sigma-70, region 4
SPH21_RS12360	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS12360	PF00593	TonB dependent receptor
SPH21_RS12370	PF00149	Calcineurin-like phosphoesterase
SPH21_RS12385	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS12385	PF00593	TonB dependent receptor
SPH21_RS12400	PF13536	Putative multidrug resistance efflux transporter
SPH21_RS12450	PF00175	Oxidoreductase NAD-binding domain 
SPH21_RS12450	PF00042	Globin
SPH21_RS12450	PF00970	Oxidoreductase FAD-binding domain
SPH21_RS12455	PF02082	Transcriptional regulator
SPH21_RS12500	PF01702	Queuine tRNA-ribosyltransferase
SPH21_RS12505	PF00535	Glycosyl transferase family 2
SPH21_RS12510	PF02527	rRNA small subunit methyltransferase G
SPH21_RS12515	PF02481	DNA recombination-mediator protein A
SPH21_RS12515	PF18255	DNA processing protein A sterile alpha motif domain
SPH21_RS12520	PF07521	Zn-dependent metallo-hydrolase RNA specificity domain
SPH21_RS12520	PF17770	Ribonuclease J C-terminal domain
SPH21_RS12520	PF12706	Beta-lactamase superfamily domain
SPH21_RS12525	PF00005	ABC transporter
SPH21_RS12525	PF00664	ABC transporter transmembrane region
SPH21_RS12535	PF01887	S-adenosyl-l-methionine hydroxide adenosyltransferase
SPH21_RS12540	PF02562	PhoH-like protein
SPH21_RS12545	PF01259	SAICAR synthetase
SPH21_RS12555	PF12706	Beta-lactamase superfamily domain
SPH21_RS12565	PF08239	Bacterial SH3 domain
SPH21_RS12565	PF01520	N-acetylmuramoyl-L-alanine amidase
SPH21_RS12570	PF11741	AMIN domain
SPH21_RS12570	PF01520	N-acetylmuramoyl-L-alanine amidase
SPH21_RS12580	PF00994	Probable molybdopterin binding domain
SPH21_RS12580	PF02464	Competence-damaged protein
SPH21_RS12580	PF18146	Damage-inducible protein CinA KH domain
SPH21_RS12585	PF02817	e3 binding domain
SPH21_RS12585	PF00364	Biotin-requiring enzyme
SPH21_RS12585	PF00198	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
SPH21_RS12595	PF00575	S1 RNA binding domain
SPH21_RS12595	PF16921	Tex protein YqgF-like domain
SPH21_RS12595	PF17674	HHH domain
SPH21_RS12595	PF09371	Tex-like protein N-terminal domain
SPH21_RS12600	PF00375	Sodium:dicarboxylate symporter family
SPH21_RS12615	PF12796	Ankyrin repeats (3 copies)
SPH21_RS12620	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS12620	PF00593	TonB dependent receptor
SPH21_RS12645	PF02899	Phage integrase, N-terminal SAM-like domain
SPH21_RS12645	PF00589	Phage integrase family
SPH21_RS12680	PF01738	Dienelactone hydrolase family
SPH21_RS12685	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS12685	PF00072	Response regulator receiver domain
SPH21_RS12690	PF18719	ArlS sensor domain
SPH21_RS12690	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS12690	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS12715	PF03741	Integral membrane protein TerC family
SPH21_RS12720	PF10017	Histidine-specific methyltransferase, SAM-dependent
SPH21_RS12725	PF03781	Sulfatase-modifying factor enzyme 1
SPH21_RS12725	PF12867	DinB superfamily
SPH21_RS12730	PF00528	Binding-protein-dependent transport system inner membrane component
SPH21_RS12735	PF00005	ABC transporter
SPH21_RS12735	PF00571	CBS domain
SPH21_RS12740	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS12740	PF02852	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
SPH21_RS12745	PF00724	NADH:flavin oxidoreductase / NADH oxidase family
SPH21_RS12755	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS12755	PF00593	TonB dependent receptor
SPH21_RS12770	PF00999	Sodium/hydrogen exchanger family
SPH21_RS12775	PF01810	LysE type translocator
SPH21_RS12785	PF04679	ATP dependent DNA ligase C terminal region        
SPH21_RS12785	PF13298	DNA polymerase Ligase (LigD)
SPH21_RS12785	PF01068	ATP dependent DNA ligase domain
SPH21_RS12800	PF08327	Activator of Hsp90 ATPase homolog 1-like protein
SPH21_RS12805	PF02311	AraC-like ligand binding domain
SPH21_RS12805	PF12833	Helix-turn-helix domain
SPH21_RS12810	PF01266	FAD dependent oxidoreductase
SPH21_RS12825	PF02492	CobW/HypB/UreG, nucleotide-binding domain
SPH21_RS12825	PF07683	Cobalamin synthesis protein cobW C-terminal domain
SPH21_RS12840	PF00005	ABC transporter
SPH21_RS12855	PF00561	alpha/beta hydrolase fold
SPH21_RS12860	PF00141	Peroxidase
SPH21_RS12875	PF13533	Biotin-lipoyl like
SPH21_RS12880	PF00873	AcrB/AcrD/AcrF family
SPH21_RS12885	PF02321	Outer membrane efflux protein
SPH21_RS12895	PF00982	Glycosyltransferase family 20
SPH21_RS12895	PF05116	Sucrose-6F-phosphate phosphohydrolase
SPH21_RS12900	PF07479	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
SPH21_RS12900	PF01210	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
SPH21_RS12940	PF02687	FtsX-like permease family
SPH21_RS12940	PF12704	MacB-like periplasmic core domain
SPH21_RS12950	PF02678	Pirin
SPH21_RS12950	PF05726	Pirin C-terminal cupin domain
SPH21_RS12960	PF03358	NADPH-dependent FMN reductase
SPH21_RS12965	PF08220	DeoR-like helix-turn-helix domain
SPH21_RS12965	PF00455	DeoR C terminal sensor domain
SPH21_RS12975	PF00456	Transketolase, thiamine diphosphate binding domain
SPH21_RS12980	PF02780	Transketolase, C-terminal domain
SPH21_RS12980	PF02779	Transketolase, pyrimidine binding domain
SPH21_RS12985	PF13407	Periplasmic binding protein domain
SPH21_RS12995	PF00005	ABC transporter
SPH21_RS13000	PF02653	Branched-chain amino acid transport system / permease component
SPH21_RS13005	PF00370	FGGY family of carbohydrate kinases, N-terminal domain
SPH21_RS13005	PF02782	FGGY family of carbohydrate kinases, C-terminal domain
SPH21_RS13015	PF02525	Flavodoxin-like fold
SPH21_RS13020	PF01638	HxlR-like helix-turn-helix
SPH21_RS13025	PF07690	Major Facilitator Superfamily
SPH21_RS13035	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS13045	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13045	PF00593	TonB dependent receptor
SPH21_RS13080	PF01758	Sodium Bile acid symporter family
SPH21_RS13090	PF13378	Enolase C-terminal domain-like
SPH21_RS13090	PF02746	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
SPH21_RS13095	PF00171	Aldehyde dehydrogenase family
SPH21_RS13105	PF00593	TonB dependent receptor
SPH21_RS13105	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13115	PF07495	Y_Y_Y domain
SPH21_RS13115	PF00072	Response regulator receiver domain
SPH21_RS13115	PF07494	Two component regulator propeller
SPH21_RS13115	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS13115	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS13115	PF12833	Helix-turn-helix domain
SPH21_RS13120	PF02449	Beta-galactosidase
SPH21_RS13120	PF08533	Beta-galactosidase C-terminal domain
SPH21_RS13120	PF08532	Beta-galactosidase trimerisation domain
SPH21_RS13125	PF17851	Beta xylosidase C-terminal Concanavalin A-like domain 
SPH21_RS13125	PF04616	Glycosyl hydrolases family 43
SPH21_RS13130	PF08533	Beta-galactosidase C-terminal domain
SPH21_RS13130	PF02449	Beta-galactosidase
SPH21_RS13130	PF08532	Beta-galactosidase trimerisation domain
SPH21_RS13135	PF00593	TonB dependent receptor
SPH21_RS13135	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13140	PF14322	Starch-binding associating with outer membrane
SPH21_RS13140	PF07980	SusD family
SPH21_RS13145	PF04616	Glycosyl hydrolases family 43
SPH21_RS13145	PF17851	Beta xylosidase C-terminal Concanavalin A-like domain 
SPH21_RS13155	PF04616	Glycosyl hydrolases family 43
SPH21_RS13155	PF17851	Beta xylosidase C-terminal Concanavalin A-like domain 
SPH21_RS13160	PF03422	Carbohydrate binding module (family 6)
SPH21_RS13160	PF00756	Putative esterase
SPH21_RS13160	PF00331	Glycosyl hydrolase family 10
SPH21_RS13160	PF00404	Dockerin type I domain
SPH21_RS13165	PF07494	Two component regulator propeller
SPH21_RS13165	PF12833	Helix-turn-helix domain
SPH21_RS13165	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS13165	PF00072	Response regulator receiver domain
SPH21_RS13165	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS13165	PF07495	Y_Y_Y domain
SPH21_RS13170	PF00331	Glycosyl hydrolase family 10
SPH21_RS13180	PF04616	Glycosyl hydrolases family 43
SPH21_RS13185	PF07980	SusD family
SPH21_RS13185	PF14322	Starch-binding associating with outer membrane
SPH21_RS13190	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13190	PF00593	TonB dependent receptor
SPH21_RS13215	PF02525	Flavodoxin-like fold
SPH21_RS13240	PF08534	Redoxin
SPH21_RS13255	PF07690	Major Facilitator Superfamily
SPH21_RS13260	PF12706	Beta-lactamase superfamily domain
SPH21_RS13270	PF00593	TonB dependent receptor
SPH21_RS13270	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13280	PF07883	Cupin domain
SPH21_RS13280	PF12833	Helix-turn-helix domain
SPH21_RS13285	PF06769	YoeB-like toxin of bacterial type II toxin-antitoxin system
SPH21_RS13295	PF01346	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
SPH21_RS13295	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
SPH21_RS13305	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13305	PF00593	TonB dependent receptor
SPH21_RS13315	PF03825	Nucleoside H+ symporter
SPH21_RS13320	PF12804	MobA-like NTP transferase domain
SPH21_RS13335	PF01066	CDP-alcohol phosphatidyltransferase
SPH21_RS13350	PF03595	Voltage-dependent anion channel
SPH21_RS13360	PF01568	Molydopterin dinucleotide binding domain
SPH21_RS13360	PF04879	Molybdopterin oxidoreductase Fe4S4 domain
SPH21_RS13360	PF00384	Molybdopterin oxidoreductase
SPH21_RS13365	PF12800	4Fe-4S binding domain
SPH21_RS13365	PF13247	4Fe-4S dicluster domain
SPH21_RS13400	PF01740	STAS domain
SPH21_RS13400	PF00916	Sulfate permease family
SPH21_RS13440	PF03746	LamB/YcsF family
SPH21_RS13445	PF02626	Carboxyltransferase domain, subdomain A and B 
SPH21_RS13450	PF02682	Carboxyltransferase domain, subdomain C and D
SPH21_RS13455	PF03976	Polyphosphate kinase 2 (PPK2)
SPH21_RS13460	PF01494	FAD binding domain
SPH21_RS13465	PF08003	Protein of unknown function (DUF1698)
SPH21_RS13470	PF00293	NUDIX domain
SPH21_RS13480	PF00005	ABC transporter
SPH21_RS13495	PF05140	ResB-like family 
SPH21_RS13495	PF01578	Cytochrome C assembly protein
SPH21_RS13510	PF02245	Methylpurine-DNA glycosylase (MPG)
SPH21_RS13600	PF13280	WYL domain
SPH21_RS13600	PF08279	HTH domain
SPH21_RS13610	PF05175	Methyltransferase small domain
SPH21_RS13610	PF17827	PrmC N-terminal domain
SPH21_RS13620	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS13620	PF13192	Thioredoxin domain
SPH21_RS13630	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS13630	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS13635	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS13635	PF07729	FCD domain
SPH21_RS13645	PF01047	MarR family
SPH21_RS13645	PF00583	Acetyltransferase (GNAT) family
SPH21_RS13660	PF00593	TonB dependent receptor
SPH21_RS13660	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13665	PF07980	SusD family
SPH21_RS13665	PF14322	Starch-binding associating with outer membrane
SPH21_RS13680	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13680	PF00593	TonB dependent receptor
SPH21_RS13685	PF14322	Starch-binding associating with outer membrane
SPH21_RS13685	PF07980	SusD family
SPH21_RS13720	PF09335	SNARE associated Golgi protein
SPH21_RS13730	PF01638	HxlR-like helix-turn-helix
SPH21_RS13735	PF00248	Aldo/keto reductase family
SPH21_RS13755	PF01011	PQQ enzyme repeat
SPH21_RS13760	PF00593	TonB dependent receptor
SPH21_RS13760	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13770	PF13378	Enolase C-terminal domain-like
SPH21_RS13770	PF02746	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
SPH21_RS13780	PF03737	Aldolase/RraA
SPH21_RS13790	PF07690	Major Facilitator Superfamily
SPH21_RS13795	PF00593	TonB dependent receptor
SPH21_RS13795	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13825	PF00593	TonB dependent receptor
SPH21_RS13825	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS13830	PF07980	SusD family
SPH21_RS13830	PF14322	Starch-binding associating with outer membrane
SPH21_RS13835	PF07470	Glycosyl Hydrolase Family 88
SPH21_RS13845	PF02870	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
SPH21_RS13845	PF12833	Helix-turn-helix domain
SPH21_RS13845	PF02805	Metal binding domain of Ada
SPH21_RS13845	PF01035	6-O-methylguanine DNA methyltransferase, DNA binding domain
SPH21_RS13850	PF00561	alpha/beta hydrolase fold
SPH21_RS13870	PF07690	Major Facilitator Superfamily
SPH21_RS13875	PF01037	Lrp/AsnC ligand binding domain
SPH21_RS13885	PF00999	Sodium/hydrogen exchanger family
SPH21_RS13900	PF01022	Bacterial regulatory protein, arsR family
SPH21_RS13925	PF00905	Penicillin binding protein transpeptidase domain
SPH21_RS13950	PF00873	AcrB/AcrD/AcrF family
SPH21_RS13955	PF00873	AcrB/AcrD/AcrF family
SPH21_RS13975	PF00183	Hsp90 protein
SPH21_RS13995	PF00574	Clp protease
SPH21_RS14010	PF13649	Methyltransferase domain
SPH21_RS14015	PF03466	LysR substrate binding domain
SPH21_RS14015	PF00126	Bacterial regulatory helix-turn-helix protein, lysR family
SPH21_RS14030	PF00583	Acetyltransferase (GNAT) family
SPH21_RS14050	PF01329	Pterin 4 alpha carbinolamine dehydratase
SPH21_RS14055	PF02321	Outer membrane efflux protein
SPH21_RS14060	PF00873	AcrB/AcrD/AcrF family
SPH21_RS14065	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
SPH21_RS14065	PF00529	HlyD membrane-fusion protein of T1SS
SPH21_RS14075	PF00877	NlpC/P60 family
SPH21_RS14095	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14095	PF00593	TonB dependent receptor
SPH21_RS14100	PF14322	Starch-binding associating with outer membrane
SPH21_RS14100	PF07980	SusD family
SPH21_RS14110	PF12795	Mechanosensitive ion channel porin domain
SPH21_RS14110	PF00924	Mechanosensitive ion channel
SPH21_RS14110	PF12794	Mechanosensitive ion channel inner membrane domain 1
SPH21_RS14115	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS14130	PF00593	TonB dependent receptor
SPH21_RS14130	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14140	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS14140	PF10518	TAT (twin-arginine translocation) pathway signal sequence
SPH21_RS14145	PF07690	Major Facilitator Superfamily
SPH21_RS14150	PF01979	Amidohydrolase family
SPH21_RS14155	PF01609	Transposase DDE domain
SPH21_RS14165	PF07995	Glucose / Sorbosone dehydrogenase
SPH21_RS14175	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS14195	PF01566	Natural resistance-associated macrophage protein
SPH21_RS14205	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14205	PF00593	TonB dependent receptor
SPH21_RS14210	PF00011	Hsp20/alpha crystallin family
SPH21_RS14225	PF00593	TonB dependent receptor
SPH21_RS14225	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14230	PF07980	SusD family
SPH21_RS14230	PF14322	Starch-binding associating with outer membrane
SPH21_RS14240	PF00703	Glycosyl hydrolases family 2
SPH21_RS14240	PF16355	Domain of unknown function (DUF4982)
SPH21_RS14240	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS14240	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS14250	PF01055	Glycosyl hydrolases family 31 
SPH21_RS14250	PF13802	Galactose mutarotase-like
SPH21_RS14250	PF17137	Domain of unknown function (DUF5110)
SPH21_RS14250	PF16338	Domain of unknown function (DUF4968)
SPH21_RS14265	PF07470	Glycosyl Hydrolase Family 88
SPH21_RS14270	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS14270	PF07494	Two component regulator propeller
SPH21_RS14270	PF12833	Helix-turn-helix domain
SPH21_RS14270	PF07495	Y_Y_Y domain
SPH21_RS14270	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS14270	PF00072	Response regulator receiver domain
SPH21_RS14275	PF00248	Aldo/keto reductase family
SPH21_RS14310	PF01261	Xylose isomerase-like TIM barrel
SPH21_RS14315	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS14320	PF13472	GDSL-like Lipase/Acylhydrolase family
SPH21_RS14340	PF17851	Beta xylosidase C-terminal Concanavalin A-like domain 
SPH21_RS14340	PF04616	Glycosyl hydrolases family 43
SPH21_RS14350	PF00593	TonB dependent receptor
SPH21_RS14350	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14360	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14360	PF00593	TonB dependent receptor
SPH21_RS14370	PF00295	Glycosyl hydrolases family 28
SPH21_RS14375	PF07470	Glycosyl Hydrolase Family 88
SPH21_RS14380	PF08125	Mannitol dehydrogenase C-terminal domain
SPH21_RS14380	PF01232	Mannitol dehydrogenase Rossmann domain
SPH21_RS14385	PF08666	SAF domain
SPH21_RS14385	PF04295	D-galactarate dehydratase / Altronate hydrolase, C terminus
SPH21_RS14390	PF02614	Glucuronate isomerase
SPH21_RS14400	PF07690	Major Facilitator Superfamily
SPH21_RS14405	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS14405	PF01548	Transposase
SPH21_RS14410	PF00245	Alkaline phosphatase
SPH21_RS14415	PF02826	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
SPH21_RS14415	PF00389	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
SPH21_RS14440	PF14322	Starch-binding associating with outer membrane
SPH21_RS14440	PF07980	SusD family
SPH21_RS14445	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14445	PF00593	TonB dependent receptor
SPH21_RS14455	PF00593	TonB dependent receptor
SPH21_RS14460	PF00230	Major intrinsic protein
SPH21_RS14465	PF02782	FGGY family of carbohydrate kinases, C-terminal domain
SPH21_RS14465	PF00370	FGGY family of carbohydrate kinases, N-terminal domain
SPH21_RS14470	PF16901	C-terminal domain of alpha-glycerophosphate oxidase
SPH21_RS14470	PF01266	FAD dependent oxidoreductase
SPH21_RS14475	PF00455	DeoR C terminal sensor domain
SPH21_RS14475	PF08220	DeoR-like helix-turn-helix domain
SPH21_RS14480	PF00085	Thioredoxin
SPH21_RS14485	PF07972	NrdI Flavodoxin like 
SPH21_RS14490	PF02867	Ribonucleotide reductase, barrel domain
SPH21_RS14490	PF08343	Ribonucleotide reductase N-terminal
SPH21_RS14490	PF00317	Ribonucleotide reductase, all-alpha domain
SPH21_RS14495	PF00268	Ribonucleotide reductase, small chain
SPH21_RS14505	PF01062	Bestrophin, RFP-TM, chloride channel
SPH21_RS14520	PF13288	DXP reductoisomerase C-terminal domain
SPH21_RS14520	PF08436	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain
SPH21_RS14520	PF02670	1-deoxy-D-xylulose 5-phosphate reductoisomerase
SPH21_RS14525	PF02163	Peptidase family M50
SPH21_RS14525	PF17820	PDZ domain
SPH21_RS14540	PF01339	CheB methylesterase
SPH21_RS14550	PF05698	Bacterial trigger factor protein (TF) C-terminus
SPH21_RS14550	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
SPH21_RS14550	PF05697	Bacterial trigger factor protein (TF)
SPH21_RS14555	PF00574	Clp protease
SPH21_RS14560	PF07724	AAA domain (Cdc48 subfamily)
SPH21_RS14560	PF06689	ClpX C4-type zinc finger
SPH21_RS14560	PF10431	C-terminal, D2-small domain, of ClpB protein 
SPH21_RS14565	PF01048	Phosphorylase superfamily
SPH21_RS14565	PF10423	Bacterial AMP nucleoside phosphorylase N-terminus 
SPH21_RS14570	PF00571	CBS domain
SPH21_RS14570	PF00291	Pyridoxal-phosphate dependent enzyme
SPH21_RS14575	PF00275	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
SPH21_RS14585	PF13361	UvrD-like helicase C-terminal domain
SPH21_RS14585	PF00580	UvrD/REP helicase N-terminal domain
SPH21_RS14610	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS14610	PF03772	Competence protein
SPH21_RS14610	PF13567	Domain of unknown function (DUF4131)
SPH21_RS14615	PF00270	DEAD/DEAH box helicase
SPH21_RS14615	PF00271	Helicase conserved C-terminal domain
SPH21_RS14615	PF00570	HRDC domain
SPH21_RS14615	PF16124	RecQ zinc-binding
SPH21_RS14615	PF09382	RQC domain
SPH21_RS14630	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14630	PF00593	TonB dependent receptor
SPH21_RS14635	PF07980	SusD family
SPH21_RS14635	PF14322	Starch-binding associating with outer membrane
SPH21_RS14645	PF02754	Cysteine-rich domain
SPH21_RS14670	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14670	PF00593	TonB dependent receptor
SPH21_RS14675	PF07980	SusD family
SPH21_RS14675	PF14322	Starch-binding associating with outer membrane
SPH21_RS14680	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14680	PF00593	TonB dependent receptor
SPH21_RS14695	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS14695	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS14715	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS14715	PF00593	TonB dependent receptor
SPH21_RS14725	PF01979	Amidohydrolase family
SPH21_RS14740	PF01758	Sodium Bile acid symporter family
SPH21_RS14745	PF03841	L-seryl-tRNA selenium transferase
SPH21_RS14745	PF12390	Selenocysteine synthase N terminal
SPH21_RS14750	PF02824	TGS domain
SPH21_RS14750	PF03129	Anticodon binding domain
SPH21_RS14750	PF00587	tRNA synthetase class II core domain (G, H, P, S and T)
SPH21_RS14750	PF07973	Threonyl and Alanyl tRNA synthetase second additional domain
SPH21_RS14755	PF00707	Translation initiation factor IF-3, C-terminal domain
SPH21_RS14755	PF05198	Translation initiation factor IF-3, N-terminal domain
SPH21_RS14760	PF01632	Ribosomal protein L35
SPH21_RS14765	PF00453	Ribosomal protein L20
SPH21_RS14770	PF00682	HMGL-like
SPH21_RS14775	PF00111	2Fe-2S iron-sulfur cluster binding domain
SPH21_RS14780	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS14785	PF01047	MarR family
SPH21_RS14790	PF07549	SecD/SecF GG Motif
SPH21_RS14790	PF02355	Protein export membrane protein
SPH21_RS14795	PF00186	Dihydrofolate reductase
SPH21_RS14800	PF00303	Thymidylate synthase
SPH21_RS14820	PF08544	GHMP kinases C terminal 
SPH21_RS14820	PF00288	GHMP kinases N terminal domain
SPH21_RS14850	PF02812	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
SPH21_RS14850	PF00208	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
SPH21_RS14855	PF02190	ATP-dependent protease La (LON) substrate-binding domain 
SPH21_RS14855	PF05362	Lon protease (S16) C-terminal proteolytic domain
SPH21_RS14855	PF00004	ATPase family associated with various cellular activities (AAA)
SPH21_RS14870	PF01676	Metalloenzyme superfamily
SPH21_RS14870	PF06415	BPG-independent PGAM N-terminus (iPGM_N)
SPH21_RS14880	PF01729	Quinolinate phosphoribosyl transferase, C-terminal domain
SPH21_RS14880	PF02749	Quinolinate phosphoribosyl transferase, N-terminal domain
SPH21_RS14885	PF02660	Glycerol-3-phosphate acyltransferase
SPH21_RS14895	PF04715	Anthranilate synthase component I, N terminal region
SPH21_RS14895	PF00117	Glutamine amidotransferase class-I
SPH21_RS14895	PF00425	chorismate binding enzyme
SPH21_RS14900	PF00709	Adenylosuccinate synthetase
SPH21_RS14905	PF01475	Ferric uptake regulator family
SPH21_RS14910	PF13291	ACT domain
SPH21_RS14910	PF02824	TGS domain
SPH21_RS14910	PF04607	Region found in RelA / SpoT proteins
SPH21_RS14920	PF00255	Glutathione peroxidase
SPH21_RS14930	PF00441	Acyl-CoA dehydrogenase, C-terminal domain
SPH21_RS14930	PF02770	Acyl-CoA dehydrogenase, middle domain
SPH21_RS14930	PF02771	Acyl-CoA dehydrogenase, N-terminal domain
SPH21_RS14940	PF00037	4Fe-4S binding domain
SPH21_RS14945	PF00582	Universal stress protein family
SPH21_RS14950	PF00877	NlpC/P60 family
SPH21_RS14955	PF17810	Arginine decarboxylase helical bundle domain
SPH21_RS14955	PF17944	Arginine decarboxylase C-terminal helical extension
SPH21_RS14955	PF02784	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
SPH21_RS14970	PF05746	DALR anticodon binding domain
SPH21_RS14970	PF00750	tRNA synthetases class I (R)
SPH21_RS14975	PF13244	Domain of unknown function (DUF4040)
SPH21_RS14975	PF00361	Proton-conducting membrane transporter
SPH21_RS14975	PF00662	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
SPH21_RS14985	PF00420	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
SPH21_RS14990	PF00361	Proton-conducting membrane transporter
SPH21_RS15000	PF04066	Multiple resistance and pH regulation protein F (MrpF / PhaF)
SPH21_RS15005	PF03334	Na+/H+ antiporter subunit
SPH21_RS15010	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS15015	PF01293	Phosphoenolpyruvate carboxykinase
SPH21_RS15025	PF01521	Iron-sulphur cluster biosynthesis
SPH21_RS15030	PF00266	Aminotransferase class-V
SPH21_RS15040	PF00654	Voltage gated chloride channel
SPH21_RS15060	PF00155	Aminotransferase class I and II
SPH21_RS15115	PF13185	GAF domain
SPH21_RS15125	PF00850	Histone deacetylase domain
SPH21_RS15130	PF00756	Putative esterase
SPH21_RS15145	PF01197	Ribosomal protein L31
SPH21_RS15155	PF00121	Triosephosphate isomerase
SPH21_RS15165	PF08245	Mur ligase middle domain
SPH21_RS15165	PF02875	Mur ligase family, glutamate ligase domain
SPH21_RS15165	PF01225	Mur ligase family, catalytic domain
SPH21_RS15185	PF04079	Segregation and condensation complex subunit ScpB
SPH21_RS15190	PF04055	Radical SAM superfamily
SPH21_RS15195	PF04055	Radical SAM superfamily
SPH21_RS15195	PF01938	TRAM domain
SPH21_RS15195	PF00919	Uncharacterized protein family UPF0004
SPH21_RS15200	PF00877	NlpC/P60 family
SPH21_RS15210	PF03796	DnaB-like helicase C terminal domain
SPH21_RS15210	PF00772	DnaB-like helicase N terminal domain
SPH21_RS15215	PF08032	RNA 2'-O ribose methyltransferase substrate binding
SPH21_RS15215	PF00588	SpoU rRNA Methylase family
SPH21_RS15220	PF03825	Nucleoside H+ symporter
SPH21_RS15230	PF01012	Electron transfer flavoprotein domain
SPH21_RS15230	PF00766	Electron transfer flavoprotein FAD-binding domain
SPH21_RS15245	PF05188	MutS domain II
SPH21_RS15245	PF05190	MutS family domain IV
SPH21_RS15245	PF01624	MutS domain I
SPH21_RS15245	PF00488	MutS domain V
SPH21_RS15245	PF05192	MutS domain III
SPH21_RS15255	PF17767	Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain
SPH21_RS15255	PF04095	Nicotinate phosphoribosyltransferase (NAPRTase) family
SPH21_RS15265	PF02405	Permease MlaE
SPH21_RS15270	PF00005	ABC transporter
SPH21_RS15280	PF03631	Virulence factor BrkB
SPH21_RS15300	PF07478	D-ala D-ala ligase C-terminus
SPH21_RS15300	PF01820	D-ala D-ala ligase N-terminus
SPH21_RS15310	PF00312	Ribosomal protein S15
SPH21_RS15335	PF01638	HxlR-like helix-turn-helix
SPH21_RS15340	PF07690	Major Facilitator Superfamily
SPH21_RS15360	PF00593	TonB dependent receptor
SPH21_RS15365	PF01138	3' exoribonuclease family, domain 1
SPH21_RS15365	PF00013	KH domain
SPH21_RS15365	PF03726	Polyribonucleotide nucleotidyltransferase, RNA binding domain
SPH21_RS15365	PF03725	3' exoribonuclease family, domain 2
SPH21_RS15365	PF00575	S1 RNA binding domain
SPH21_RS15370	PF00834	Ribulose-phosphate 3 epimerase family
SPH21_RS15375	PF00266	Aminotransferase class-V
SPH21_RS15380	PF00389	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
SPH21_RS15380	PF02826	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
SPH21_RS15390	PF00348	Polyprenyl synthetase
SPH21_RS15395	PF00773	RNB domain
SPH21_RS15395	PF08206	Ribonuclease B OB domain
SPH21_RS15395	PF00575	S1 RNA binding domain
SPH21_RS15395	PF17876	Cold shock domain
SPH21_RS15400	PF01475	Ferric uptake regulator family
SPH21_RS15405	PF01790	Prolipoprotein diacylglyceryl transferase
SPH21_RS15410	PF03641	Possible lysine decarboxylase
SPH21_RS15415	PF13662	Toprim domain
SPH21_RS15415	PF02132	RecR protein
SPH21_RS15420	PF00106	short chain dehydrogenase
SPH21_RS15425	PF00591	Glycosyl transferase family, a/b domain
SPH21_RS15425	PF02885	Glycosyl transferase family, helical bundle domain
SPH21_RS15430	PF00697	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
SPH21_RS15435	PF00291	Pyridoxal-phosphate dependent enzyme
SPH21_RS15440	PF00290	Tryptophan synthase alpha chain
SPH21_RS15450	PF01546	Peptidase family M20/M25/M40
SPH21_RS15450	PF07687	Peptidase dimerisation domain
SPH21_RS15455	PF07973	Threonyl and Alanyl tRNA synthetase second additional domain
SPH21_RS15455	PF01411	tRNA synthetases class II (A)
SPH21_RS15455	PF02272	DHHA1 domain
SPH21_RS15460	PF00578	AhpC/TSA family
SPH21_RS15465	PF00072	Response regulator receiver domain
SPH21_RS15465	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS15470	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS15470	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS15470	PF00989	PAS fold
SPH21_RS15470	PF16736	Single Cache-like 
SPH21_RS15475	PF01479	S4 domain
SPH21_RS15475	PF00849	RNA pseudouridylate synthase
SPH21_RS15480	PF00725	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
SPH21_RS15480	PF02737	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
SPH21_RS15495	PF04052	TolB amino-terminal domain
SPH21_RS15495	PF07676	WD40-like Beta Propeller Repeat
SPH21_RS15500	PF00905	Penicillin binding protein transpeptidase domain
SPH21_RS15500	PF00912	Transglycosylase
SPH21_RS15500	PF17092	Penicillin-binding protein OB-like domain
SPH21_RS15505	PF13419	Haloacid dehalogenase-like hydrolase
SPH21_RS15515	PF13732	Domain of unknown function (DUF4162)
SPH21_RS15515	PF00005	ABC transporter
SPH21_RS15525	PF00684	DnaJ central domain
SPH21_RS15525	PF01556	DnaJ C terminal domain
SPH21_RS15525	PF00226	DnaJ domain
SPH21_RS15530	PF01025	GrpE
SPH21_RS15535	PF00005	ABC transporter
SPH21_RS15580	PF01926	50S ribosome-binding GTPase
SPH21_RS15580	PF06071	Protein of unknown function (DUF933)
SPH21_RS15585	PF00480	ROK family
SPH21_RS15585	PF01325	Iron dependent repressor, N-terminal DNA binding domain
SPH21_RS15590	PF00593	TonB dependent receptor
SPH21_RS15590	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS15600	PF14310	Fibronectin type III-like domain
SPH21_RS15600	PF00933	Glycosyl hydrolase family 3 N terminal domain
SPH21_RS15600	PF01915	Glycosyl hydrolase family 3 C-terminal domain
SPH21_RS15605	PF00575	S1 RNA binding domain
SPH21_RS15610	PF02224	Cytidylate kinase
SPH21_RS15615	PF03462	PCRF domain
SPH21_RS15615	PF00472	RF-1 domain
SPH21_RS15640	PF02545	Maf-like protein
SPH21_RS15650	PF00316	Fructose-1-6-bisphosphatase, N-terminal domain
SPH21_RS15660	PF00999	Sodium/hydrogen exchanger family
SPH21_RS15660	PF00582	Universal stress protein family
SPH21_RS15665	PF00180	Isocitrate/isopropylmalate dehydrogenase
SPH21_RS15670	PF00158	Sigma-54 interaction domain
SPH21_RS15670	PF00072	Response regulator receiver domain
SPH21_RS15670	PF02954	Bacterial regulatory protein, Fis family
SPH21_RS15675	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS15675	PF09308	LuxQ, periplasmic
SPH21_RS15675	PF00072	Response regulator receiver domain
SPH21_RS15675	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS15680	PF10431	C-terminal, D2-small domain, of ClpB protein 
SPH21_RS15680	PF17871	AAA lid domain
SPH21_RS15680	PF07724	AAA domain (Cdc48 subfamily)
SPH21_RS15680	PF00004	ATPase family associated with various cellular activities (AAA)
SPH21_RS15680	PF02861	Clp amino terminal domain, pathogenicity island component
SPH21_RS15690	PF00156	Phosphoribosyl transferase domain
SPH21_RS15695	PF00293	NUDIX domain
SPH21_RS15700	PF01467	Cytidylyltransferase-like
SPH21_RS15720	PF01177	Asp/Glu/Hydantoin racemase
SPH21_RS15725	PF01645	Conserved region in glutamate synthase
SPH21_RS15730	PF01220	Dehydroquinase class II
SPH21_RS15740	PF00535	Glycosyl transferase family 2
SPH21_RS15755	PF12805	FUSC-like inner membrane protein yccS
SPH21_RS15760	PF00311	Phosphoenolpyruvate carboxylase
SPH21_RS15770	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS15770	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS15780	PF02503	Polyphosphate kinase middle domain
SPH21_RS15780	PF13090	Polyphosphate kinase C-terminal domain 2
SPH21_RS15780	PF17941	Polyphosphate kinase C-terminal domain 1
SPH21_RS15780	PF13089	Polyphosphate kinase N-terminal domain
SPH21_RS15790	PF01842	ACT domain
SPH21_RS15790	PF00696	Amino acid kinase family
SPH21_RS15795	PF00278	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
SPH21_RS15795	PF02784	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
SPH21_RS15805	PF13368	Topoisomerase C-terminal repeat
SPH21_RS15805	PF01751	Toprim domain
SPH21_RS15805	PF01131	DNA topoisomerase
SPH21_RS15820	PF00731	AIR carboxylase
SPH21_RS15825	PF02222	ATP-grasp domain
SPH21_RS15825	PF17769	Phosphoribosylaminoimidazole carboxylase C-terminal domain
SPH21_RS15830	PF01058	NADH ubiquinone oxidoreductase, 20 Kd subunit
SPH21_RS15835	PF00507	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
SPH21_RS15845	PF00923	Transaldolase/Fructose-6-phosphate aldolase
SPH21_RS15850	PF01493	GXGXG motif
SPH21_RS15850	PF00310	Glutamine amidotransferases class-II
SPH21_RS15850	PF04898	Glutamate synthase central domain
SPH21_RS15850	PF01645	Conserved region in glutamate synthase
SPH21_RS15855	PF14691	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
SPH21_RS15855	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS15875	PF08032	RNA 2'-O ribose methyltransferase substrate binding
SPH21_RS15875	PF00588	SpoU rRNA Methylase family
SPH21_RS15890	PF01077	Nitrite and sulphite reductase 4Fe-4S domain
SPH21_RS15890	PF03460	Nitrite/Sulfite reductase ferredoxin-like half domain
SPH21_RS15895	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
SPH21_RS15895	PF14824	Sirohaem biosynthesis protein central
SPH21_RS15895	PF10414	Sirohaem synthase dimerisation region
SPH21_RS15900	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
SPH21_RS15900	PF14824	Sirohaem biosynthesis protein central
SPH21_RS15900	PF10414	Sirohaem synthase dimerisation region
SPH21_RS15905	PF01507	Phosphoadenosine phosphosulfate reductase family
SPH21_RS15910	PF01507	Phosphoadenosine phosphosulfate reductase family
SPH21_RS15915	PF00009	Elongation factor Tu GTP binding domain
SPH21_RS15925	PF11798	IMS family HHH motif
SPH21_RS15925	PF00817	impB/mucB/samB family
SPH21_RS15925	PF11799	impB/mucB/samB family C-terminal domain
SPH21_RS15930	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS15930	PF00072	Response regulator receiver domain
SPH21_RS15935	PF04439	Streptomycin adenylyltransferase
SPH21_RS15940	PF00072	Response regulator receiver domain
SPH21_RS15940	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS15945	PF00085	Thioredoxin
SPH21_RS15960	PF03193	RsgA GTPase
SPH21_RS15965	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS15965	PF00072	Response regulator receiver domain
SPH21_RS15975	PF00072	Response regulator receiver domain
SPH21_RS15975	PF04397	LytTr DNA-binding domain
SPH21_RS16005	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS16005	PF07730	Histidine kinase
SPH21_RS16005	PF00672	HAMP domain
SPH21_RS16010	PF00155	Aminotransferase class I and II
SPH21_RS16020	PF02780	Transketolase, C-terminal domain
SPH21_RS16020	PF02779	Transketolase, pyrimidine binding domain
SPH21_RS16025	PF01264	Chorismate synthase
SPH21_RS16030	PF00275	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
SPH21_RS16035	PF00793	DAHP synthetase I family
SPH21_RS16035	PF18152	DAHP synthase ferredoxin-like domain
SPH21_RS16040	PF00800	Prephenate dehydratase
SPH21_RS16040	PF01817	Chorismate mutase type II
SPH21_RS16040	PF01842	ACT domain
SPH21_RS16045	PF00909	Ammonium Transporter Family
SPH21_RS16060	PF06965	Na+/H+ antiporter 1
SPH21_RS16085	PF12833	Helix-turn-helix domain
SPH21_RS16085	PF02311	AraC-like ligand binding domain
SPH21_RS16105	PF06831	Formamidopyrimidine-DNA glycosylase H2TH domain
SPH21_RS16105	PF01149	Formamidopyrimidine-DNA glycosylase N-terminal domain
SPH21_RS16105	PF06827	Zinc finger found in FPG and IleRS
SPH21_RS16110	PF00383	Cytidine and deoxycytidylate deaminase zinc-binding region
SPH21_RS16120	PF00534	Glycosyl transferases group 1
SPH21_RS16120	PF13439	Glycosyltransferase Family 4
SPH21_RS16125	PF00011	Hsp20/alpha crystallin family
SPH21_RS16170	PF02028	BCCT, betaine/carnitine/choline family transporter
SPH21_RS16185	PF13378	Enolase C-terminal domain-like
SPH21_RS16185	PF02746	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
SPH21_RS16195	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS16195	PF00183	Hsp90 protein
SPH21_RS16200	PF02800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
SPH21_RS16200	PF00044	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
SPH21_RS16205	PF04542	Sigma-70 region 2 
SPH21_RS16205	PF03979	Sigma-70 factor, region 1.1
SPH21_RS16205	PF04545	Sigma-70, region 4
SPH21_RS16205	PF04539	Sigma-70 region 3
SPH21_RS16205	PF00140	Sigma-70 factor, region 1.2
SPH21_RS16220	PF13580	SIS domain
SPH21_RS16240	PF07075	Protein of unknown function (DUF1343)
SPH21_RS16250	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS16250	PF00593	TonB dependent receptor
SPH21_RS16260	PF00593	TonB dependent receptor
SPH21_RS16260	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS16275	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS16275	PF00593	TonB dependent receptor
SPH21_RS16280	PF00455	DeoR C terminal sensor domain
SPH21_RS16280	PF08220	DeoR-like helix-turn-helix domain
SPH21_RS16300	PF04151	Bacterial pre-peptidase C-terminal domain
SPH21_RS16300	PF04389	Peptidase family M28
SPH21_RS16305	PF02463	RecF/RecN/SMC N terminal domain
SPH21_RS16305	PF06470	SMC proteins Flexible Hinge Domain
SPH21_RS16315	PF00795	Carbon-nitrogen hydrolase
SPH21_RS16320	PF00155	Aminotransferase class I and II
SPH21_RS16330	PF02653	Branched-chain amino acid transport system / permease component
SPH21_RS16335	PF00005	ABC transporter
SPH21_RS16335	PF12558	ATP-binding cassette cobalt transporter
SPH21_RS16340	PF00005	ABC transporter
SPH21_RS16355	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS16360	PF01039	Carboxyl transferase domain
SPH21_RS16365	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS16370	PF00893	Small Multidrug Resistance protein
SPH21_RS16385	PF04055	Radical SAM superfamily
SPH21_RS16390	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS16395	PF01636	Phosphotransferase enzyme family
SPH21_RS16405	PF00075	RNase H
SPH21_RS16420	PF04542	Sigma-70 region 2 
SPH21_RS16420	PF08281	Sigma-70, region 4
SPH21_RS16425	PF00375	Sodium:dicarboxylate symporter family
SPH21_RS16435	PF00491	Arginase family
SPH21_RS16440	PF01979	Amidohydrolase family
SPH21_RS16445	PF17392	Urocanase C-terminal domain
SPH21_RS16445	PF01175	Urocanase Rossmann-like domain
SPH21_RS16445	PF17391	Urocanase N-terminal domain
SPH21_RS16450	PF00221	Aromatic amino acid lyase
SPH21_RS16460	PF00829	Ribosomal prokaryotic L21 protein
SPH21_RS16465	PF01016	Ribosomal L27 protein
SPH21_RS16470	PF00733	Asparagine synthase
SPH21_RS16470	PF13537	Glutamine amidotransferase domain
SPH21_RS16475	PF00501	AMP-binding enzyme
SPH21_RS16490	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS16490	PF00155	Aminotransferase class I and II
SPH21_RS16500	PF00155	Aminotransferase class I and II
SPH21_RS16510	PF06968	Biotin and Thiamin Synthesis associated domain
SPH21_RS16510	PF04055	Radical SAM superfamily
SPH21_RS16515	PF00202	Aminotransferase class-III
SPH21_RS16520	PF02311	AraC-like ligand binding domain
SPH21_RS16520	PF12833	Helix-turn-helix domain
SPH21_RS16530	PF12787	EcsC protein family
SPH21_RS16540	PF01975	Survival protein SurE
SPH21_RS16545	PF00781	Diacylglycerol kinase catalytic domain
SPH21_RS16555	PF12833	Helix-turn-helix domain
SPH21_RS16555	PF14525	AraC-binding-like domain
SPH21_RS16565	PF13509	S1 domain
SPH21_RS16565	PF17783	CvfB-like winged helix domain
SPH21_RS16590	PF03062	MBOAT, membrane-bound O-acyltransferase family
SPH21_RS16610	PF00561	alpha/beta hydrolase fold
SPH21_RS16615	PF01300	Telomere recombination
SPH21_RS16620	PF01336	OB-fold nucleic acid binding domain
SPH21_RS16620	PF00152	tRNA synthetases class II (D, K and N) 
SPH21_RS16625	PF00549	CoA-ligase
SPH21_RS16625	PF08442	ATP-grasp domain
SPH21_RS16630	PF01966	HD domain
SPH21_RS16635	PF00346	Respiratory-chain NADH dehydrogenase, 49 Kd subunit
SPH21_RS16640	PF00329	Respiratory-chain NADH dehydrogenase, 30 Kd subunit
SPH21_RS16645	PF01243	Pyridoxamine 5'-phosphate oxidase
SPH21_RS16645	PF10590	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region
SPH21_RS16650	PF02622	Uncharacterized ACR, COG1678
SPH21_RS16655	PF00072	Response regulator receiver domain
SPH21_RS16655	PF00158	Sigma-54 interaction domain
SPH21_RS16655	PF02954	Bacterial regulatory protein, Fis family
SPH21_RS16670	PF02630	SCO1/SenC
SPH21_RS16690	PF07690	Major Facilitator Superfamily
SPH21_RS16695	PF00873	AcrB/AcrD/AcrF family
SPH21_RS16705	PF13533	Biotin-lipoyl like
SPH21_RS16715	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS16715	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS16715	PF00672	HAMP domain
SPH21_RS16720	PF00072	Response regulator receiver domain
SPH21_RS16720	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS16730	PF01218	Coproporphyrinogen III oxidase
SPH21_RS16735	PF00521	DNA gyrase/topoisomerase IV, subunit A
SPH21_RS16735	PF03989	DNA gyrase C-terminal domain, beta-propeller
SPH21_RS16750	PF01380	SIS domain
SPH21_RS16750	PF00571	CBS domain
SPH21_RS16755	PF00271	Helicase conserved C-terminal domain
SPH21_RS16755	PF16124	RecQ zinc-binding
SPH21_RS16755	PF09382	RQC domain
SPH21_RS16755	PF00570	HRDC domain
SPH21_RS16755	PF00270	DEAD/DEAH box helicase
SPH21_RS16760	PF00793	DAHP synthetase I family
SPH21_RS16765	PF01841	Transglutaminase-like superfamily
SPH21_RS16765	PF08379	Bacterial transglutaminase-like N-terminal region
SPH21_RS16775	PF14403	Circularly permuted ATP-grasp type 2 
SPH21_RS16810	PF00248	Aldo/keto reductase family
SPH21_RS16820	PF00300	Histidine phosphatase superfamily (branch 1)
SPH21_RS16825	PF04055	Radical SAM superfamily
SPH21_RS16840	PF01053	Cys/Met metabolism PLP-dependent enzyme
SPH21_RS16845	PF00561	alpha/beta hydrolase fold
SPH21_RS16850	PF01842	ACT domain
SPH21_RS16850	PF03447	Homoserine dehydrogenase, NAD binding domain
SPH21_RS16850	PF00742	Homoserine dehydrogenase
SPH21_RS16860	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS16860	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS16875	PF01183	Glycosyl hydrolases family 25
SPH21_RS16880	PF05175	Methyltransferase small domain
SPH21_RS16880	PF17827	PrmC N-terminal domain
SPH21_RS16885	PF01872	RibD C-terminal domain
SPH21_RS16885	PF00383	Cytidine and deoxycytidylate deaminase zinc-binding region
SPH21_RS16895	PF09186	Domain of unknown function (DUF1949)
SPH21_RS16895	PF01205	Uncharacterized protein family UPF0029
SPH21_RS16900	PF01048	Phosphorylase superfamily
SPH21_RS16905	PF08279	HTH domain
SPH21_RS16905	PF13280	WYL domain
SPH21_RS16910	PF13673	Acetyltransferase (GNAT) domain
SPH21_RS16915	PF04264	YceI-like domain
SPH21_RS16920	PF01548	Transposase
SPH21_RS16920	PF02371	Transposase IS116/IS110/IS902 family
SPH21_RS16925	PF00593	TonB dependent receptor
SPH21_RS16925	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS16980	PF00072	Response regulator receiver domain
SPH21_RS16980	PF04397	LytTr DNA-binding domain
SPH21_RS16990	PF00455	DeoR C terminal sensor domain
SPH21_RS16990	PF08220	DeoR-like helix-turn-helix domain
SPH21_RS17000	PF00005	ABC transporter
SPH21_RS17000	PF02687	FtsX-like permease family
SPH21_RS17000	PF12704	MacB-like periplasmic core domain
SPH21_RS17005	PF00005	ABC transporter
SPH21_RS17010	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
SPH21_RS17020	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS17020	PF07694	5TMR of 5TMR-LYT
SPH21_RS17020	PF06580	Histidine kinase
SPH21_RS17025	PF00072	Response regulator receiver domain
SPH21_RS17025	PF04397	LytTr DNA-binding domain
SPH21_RS17030	PF00072	Response regulator receiver domain
SPH21_RS17030	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS17050	PF00248	Aldo/keto reductase family
SPH21_RS17065	PF02735	Ku70/Ku80 beta-barrel domain
SPH21_RS17075	PF02812	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
SPH21_RS17075	PF00208	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
SPH21_RS17080	PF11799	impB/mucB/samB family C-terminal domain
SPH21_RS17080	PF11798	IMS family HHH motif
SPH21_RS17080	PF00817	impB/mucB/samB family
SPH21_RS17085	PF17657	Bacterial DNA polymerase III alpha subunit finger domain
SPH21_RS17085	PF14579	Helix-hairpin-helix motif
SPH21_RS17085	PF02811	PHP domain
SPH21_RS17085	PF07733	Bacterial DNA polymerase III alpha NTPase domain
SPH21_RS17090	PF11490	DNA polymerase III polC-type N-terminus II
SPH21_RS17090	PF17657	Bacterial DNA polymerase III alpha subunit finger domain
SPH21_RS17090	PF07733	Bacterial DNA polymerase III alpha NTPase domain
SPH21_RS17090	PF00929	Exonuclease
SPH21_RS17090	PF01336	OB-fold nucleic acid binding domain
SPH21_RS17090	PF14579	Helix-hairpin-helix motif
SPH21_RS17090	PF02811	PHP domain
SPH21_RS17095	PF00593	TonB dependent receptor
SPH21_RS17095	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS17120	PF00593	TonB dependent receptor
SPH21_RS17125	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS17125	PF02852	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
SPH21_RS17130	PF01734	Patatin-like phospholipase
SPH21_RS17135	PF07670	Nucleoside recognition
SPH21_RS17145	PF00485	Phosphoribulokinase / Uridine kinase family
SPH21_RS17160	PF00403	Heavy-metal-associated domain
SPH21_RS17170	PF03881	Fructosamine kinase
SPH21_RS17175	PF03144	Elongation factor Tu domain 2
SPH21_RS17175	PF06421	GTP-binding protein LepA C-terminus
SPH21_RS17175	PF00679	Elongation factor G C-terminus
SPH21_RS17175	PF00009	Elongation factor Tu GTP binding domain
SPH21_RS17180	PF02882	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
SPH21_RS17180	PF00763	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
SPH21_RS17190	PF01261	Xylose isomerase-like TIM barrel
SPH21_RS17195	PF02424	ApbE family
SPH21_RS17200	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS17200	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS17205	PF03781	Sulfatase-modifying factor enzyme 1
SPH21_RS17210	PF04343	Protein of unknown function, DUF488
SPH21_RS17220	PF00589	Phage integrase family
SPH21_RS17220	PF14659	Phage integrase, N-terminal SAM-like domain
SPH21_RS17310	PF01844	HNH endonuclease
SPH21_RS17335	PF00574	Clp protease
SPH21_RS17475	PF00579	tRNA synthetases class I (W and Y)
SPH21_RS17480	PF01712	Deoxynucleoside kinase
SPH21_RS17485	PF02348	Cytidylyltransferase
SPH21_RS17490	PF01923	Cobalamin adenosyltransferase
SPH21_RS17495	PF00005	ABC transporter
SPH21_RS17505	PF00271	Helicase conserved C-terminal domain
SPH21_RS17505	PF00270	DEAD/DEAH box helicase
SPH21_RS17510	PF06418	CTP synthase N-terminus
SPH21_RS17510	PF00117	Glutamine amidotransferase class-I
SPH21_RS17515	PF02096	60Kd inner membrane protein
SPH21_RS17515	PF14849	YidC periplasmic domain
SPH21_RS17520	PF00989	PAS fold
SPH21_RS17520	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS17520	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS17525	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS17525	PF00072	Response regulator receiver domain
SPH21_RS17535	PF06969	HemN C-terminal domain
SPH21_RS17535	PF04055	Radical SAM superfamily
SPH21_RS17540	PF00403	Heavy-metal-associated domain
SPH21_RS17550	PF00115	Cytochrome C and Quinol oxidase polypeptide I
SPH21_RS17560	PF14715	N-terminal domain of cytochrome oxidase-cbb3, FixP 
SPH21_RS17560	PF13442	Cytochrome C oxidase, cbb3-type, subunit III 
SPH21_RS17565	PF12801	4Fe-4S binding domain
SPH21_RS17565	PF11614	IG-like fold at C-terminal of FixG, putative oxidoreductase
SPH21_RS17565	PF13746	4Fe-4S dicluster domain
SPH21_RS17590	PF08331	Domain of unknown function (DUF1730)
SPH21_RS17595	PF01180	Dihydroorotate dehydrogenase
SPH21_RS17600	PF12848	ABC transporter
SPH21_RS17600	PF16326	ABC transporter C-terminal domain
SPH21_RS17600	PF00005	ABC transporter
SPH21_RS17610	PF03061	Thioesterase superfamily
SPH21_RS17620	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
SPH21_RS17625	PF03190	Protein of unknown function, DUF255
SPH21_RS17630	PF02746	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
SPH21_RS17630	PF13378	Enolase C-terminal domain-like
SPH21_RS17640	PF01321	Creatinase/Prolidase N-terminal domain
SPH21_RS17640	PF00557	Metallopeptidase family M24
SPH21_RS17645	PF03819	MazG nucleotide pyrophosphohydrolase domain
SPH21_RS17655	PF02911	Formyl transferase, C-terminal domain
SPH21_RS17655	PF00551	Formyl transferase
SPH21_RS17665	PF00849	RNA pseudouridylate synthase
SPH21_RS17670	PF00072	Response regulator receiver domain
SPH21_RS17670	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS17685	PF00698	Acyl transferase domain
SPH21_RS17685	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS17685	PF08659	KR domain
SPH21_RS17685	PF00550	Phosphopantetheine attachment site
SPH21_RS17685	PF14765	Polyketide synthase dehydratase
SPH21_RS17710	PF01609	Transposase DDE domain
SPH21_RS17850	PF13545	Crp-like helix-turn-helix domain
SPH21_RS17850	PF00027	Cyclic nucleotide-binding domain
SPH21_RS17855	PF01925	Sulfite exporter TauE/SafE
SPH21_RS17860	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS17860	PF00581	Rhodanese-like domain
SPH21_RS17880	PF00085	Thioredoxin
SPH21_RS17900	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS17910	PF00857	Isochorismatase family
SPH21_RS17925	PF00873	AcrB/AcrD/AcrF family
SPH21_RS17930	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
SPH21_RS17935	PF08534	Redoxin
SPH21_RS17945	PF11412	Disulphide bond corrector protein DsbC
SPH21_RS17945	PF02683	Cytochrome C biogenesis protein transmembrane region
SPH21_RS17950	PF00578	AhpC/TSA family
SPH21_RS17955	PF00578	AhpC/TSA family
SPH21_RS17965	PF01751	Toprim domain
SPH21_RS17965	PF01131	DNA topoisomerase
SPH21_RS17995	PF07969	Amidohydrolase family
SPH21_RS18000	PF00326	Prolyl oligopeptidase family
SPH21_RS18000	PF07676	WD40-like Beta Propeller Repeat
SPH21_RS18000	PF00930	Dipeptidyl peptidase IV (DPP IV) N-terminal region
SPH21_RS18025	PF08328	Adenylosuccinate lyase C-terminal
SPH21_RS18025	PF00206	Lyase
SPH21_RS18030	PF01106	NifU-like domain
SPH21_RS18035	PF00459	Inositol monophosphatase family
SPH21_RS18040	PF01790	Prolipoprotein diacylglyceryl transferase
SPH21_RS18050	PF00285	Citrate synthase, C-terminal domain
SPH21_RS18065	PF00593	TonB dependent receptor
SPH21_RS18065	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS18080	PF00378	Enoyl-CoA hydratase/isomerase
SPH21_RS18095	PF13533	Biotin-lipoyl like
SPH21_RS18100	PF00873	AcrB/AcrD/AcrF family
SPH21_RS18120	PF00293	NUDIX domain
SPH21_RS18125	PF05175	Methyltransferase small domain
SPH21_RS18135	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS18135	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS18140	PF00732	GMC oxidoreductase
SPH21_RS18140	PF05199	GMC oxidoreductase
SPH21_RS18145	PF03825	Nucleoside H+ symporter
SPH21_RS18150	PF00571	CBS domain
SPH21_RS18150	PF00478	IMP dehydrogenase / GMP reductase domain
SPH21_RS18155	PF16658	Class II release factor RF3, C-terminal domain
SPH21_RS18155	PF00009	Elongation factor Tu GTP binding domain
SPH21_RS18155	PF03144	Elongation factor Tu domain 2
SPH21_RS18195	PF01472	PUA domain
SPH21_RS18195	PF00696	Amino acid kinase family
SPH21_RS18215	PF01551	Peptidase family M23
SPH21_RS18215	PF08460	Bacterial SH3 domain
SPH21_RS18225	PF00899	ThiF family
SPH21_RS18245	PF00403	Heavy-metal-associated domain
SPH21_RS18255	PF00873	AcrB/AcrD/AcrF family
SPH21_RS18270	PF07411	Domain of unknown function (DUF1508)
SPH21_RS18285	PF01594	AI-2E family transporter
SPH21_RS18290	PF01751	Toprim domain
SPH21_RS18290	PF01131	DNA topoisomerase
SPH21_RS18300	PF00171	Aldehyde dehydrogenase family
SPH21_RS18310	PF00675	Insulinase (Peptidase family M16)
SPH21_RS18310	PF05193	Peptidase M16 inactive domain
SPH21_RS18315	PF00291	Pyridoxal-phosphate dependent enzyme
SPH21_RS18320	PF00202	Aminotransferase class-III
SPH21_RS18325	PF01595	Cyclin M transmembrane N-terminal domain
SPH21_RS18325	PF03471	Transporter associated domain
SPH21_RS18325	PF00571	CBS domain
SPH21_RS18330	PF12833	Helix-turn-helix domain
SPH21_RS18330	PF02805	Metal binding domain of Ada
SPH21_RS18350	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS18350	PF00698	Acyl transferase domain
SPH21_RS18350	PF16197	Ketoacyl-synthetase C-terminal extension
SPH21_RS18350	PF00109	Beta-ketoacyl synthase, N-terminal domain
SPH21_RS18350	PF02801	Beta-ketoacyl synthase, C-terminal domain
SPH21_RS18350	PF08659	KR domain
SPH21_RS18350	PF00550	Phosphopantetheine attachment site
SPH21_RS18350	PF14765	Polyketide synthase dehydratase
SPH21_RS18355	PF14765	Polyketide synthase dehydratase
SPH21_RS18355	PF02801	Beta-ketoacyl synthase, C-terminal domain
SPH21_RS18355	PF00109	Beta-ketoacyl synthase, N-terminal domain
SPH21_RS18355	PF00550	Phosphopantetheine attachment site
SPH21_RS18355	PF08659	KR domain
SPH21_RS18355	PF00698	Acyl transferase domain
SPH21_RS18355	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS18355	PF16197	Ketoacyl-synthetase C-terminal extension
SPH21_RS18360	PF00550	Phosphopantetheine attachment site
SPH21_RS18370	PF07690	Major Facilitator Superfamily
SPH21_RS18385	PF01609	Transposase DDE domain
SPH21_RS18395	PF01471	Putative peptidoglycan binding domain
SPH21_RS18395	PF03572	Peptidase family S41
SPH21_RS18395	PF17820	PDZ domain
SPH21_RS18425	PF00593	TonB dependent receptor
SPH21_RS18425	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS18435	PF01032	FecCD transport family
SPH21_RS18440	PF00005	ABC transporter
SPH21_RS18445	PF12833	Helix-turn-helix domain
SPH21_RS18460	PF13520	Amino acid permease
SPH21_RS18480	PF04101	Glycosyltransferase family 28 C-terminal domain
SPH21_RS18480	PF00201	UDP-glucoronosyl and UDP-glucosyl transferase
SPH21_RS18490	PF00561	alpha/beta hydrolase fold
SPH21_RS18495	PF03733	Inner membrane component domain
SPH21_RS18535	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS18535	PF07730	Histidine kinase
SPH21_RS18535	PF05384	Sensor protein DegS
SPH21_RS18555	PF00106	short chain dehydrogenase
SPH21_RS18570	PF05974	Domain of unknown function (DUF892)
SPH21_RS18580	PF18146	Damage-inducible protein CinA KH domain
SPH21_RS18580	PF02464	Competence-damaged protein
SPH21_RS18580	PF00994	Probable molybdopterin binding domain
SPH21_RS18590	PF01967	MoaC family
SPH21_RS18590	PF00994	Probable molybdopterin binding domain
SPH21_RS18595	PF00899	ThiF family
SPH21_RS18595	PF00581	Rhodanese-like domain
SPH21_RS18605	PF01925	Sulfite exporter TauE/SafE
SPH21_RS18610	PF03454	MoeA C-terminal region (domain IV)
SPH21_RS18610	PF00994	Probable molybdopterin binding domain
SPH21_RS18610	PF03453	MoeA N-terminal region (domain I and II)
SPH21_RS18615	PF04055	Radical SAM superfamily
SPH21_RS18615	PF06463	Molybdenum Cofactor Synthesis C
SPH21_RS18625	PF13478	XdhC Rossmann domain
SPH21_RS18625	PF02625	XdhC and CoxI family
SPH21_RS18630	PF00266	Aminotransferase class-V
SPH21_RS18645	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS18645	PF00072	Response regulator receiver domain
SPH21_RS18650	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS18650	PF07730	Histidine kinase
SPH21_RS18665	PF01077	Nitrite and sulphite reductase 4Fe-4S domain
SPH21_RS18665	PF03460	Nitrite/Sulfite reductase ferredoxin-like half domain
SPH21_RS18665	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS18665	PF13806	Rieske-like [2Fe-2S] domain
SPH21_RS18665	PF18267	Rubredoxin NAD+ reductase C-terminal domain
SPH21_RS18665	PF04324	BFD-like [2Fe-2S] binding domain
SPH21_RS18670	PF14824	Sirohaem biosynthesis protein central
SPH21_RS18670	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
SPH21_RS18670	PF10414	Sirohaem synthase dimerisation region
SPH21_RS18675	PF10414	Sirohaem synthase dimerisation region
SPH21_RS18675	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
SPH21_RS18680	PF00994	Probable molybdopterin binding domain
SPH21_RS18680	PF03454	MoeA C-terminal region (domain IV)
SPH21_RS18680	PF03453	MoeA N-terminal region (domain I and II)
SPH21_RS18685	PF07690	Major Facilitator Superfamily
SPH21_RS18690	PF04879	Molybdopterin oxidoreductase Fe4S4 domain
SPH21_RS18690	PF00384	Molybdopterin oxidoreductase
SPH21_RS18690	PF01568	Molydopterin dinucleotide binding domain
SPH21_RS18720	PF00005	ABC transporter
SPH21_RS18720	PF00664	ABC transporter transmembrane region
SPH21_RS18725	PF00005	ABC transporter
SPH21_RS18725	PF00664	ABC transporter transmembrane region
SPH21_RS18735	PF07690	Major Facilitator Superfamily
SPH21_RS18755	PF00005	ABC transporter
SPH21_RS18765	PF03702	Anhydro-N-acetylmuramic acid kinase
SPH21_RS18775	PF02838	Glycosyl hydrolase family 20, domain 2
SPH21_RS18775	PF00728	Glycosyl hydrolase family 20, catalytic domain
SPH21_RS18775	PF03173	Putative carbohydrate binding domain
SPH21_RS18775	PF03174	Chitobiase/beta-hexosaminidase C-terminal domain
SPH21_RS18790	PF02308	MgtC family
SPH21_RS18805	PF00324	Amino acid permease
SPH21_RS18830	PF00106	short chain dehydrogenase
SPH21_RS18835	PF00072	Response regulator receiver domain
SPH21_RS18835	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS18845	PF00302	Chloramphenicol acetyltransferase
SPH21_RS18860	PF00892	EamA-like transporter family
SPH21_RS18875	PF11941	Domain of unknown function (DUF3459)
SPH21_RS18875	PF00128	Alpha amylase, catalytic domain
SPH21_RS18880	PF05974	Domain of unknown function (DUF892)
SPH21_RS18900	PF00107	Zinc-binding dehydrogenase
SPH21_RS18900	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS18900	PF13823	Alcohol dehydrogenase GroES-associated
SPH21_RS18925	PF16657	Maltogenic Amylase, C-terminal domain
SPH21_RS18925	PF00128	Alpha amylase, catalytic domain
SPH21_RS18930	PF00128	Alpha amylase, catalytic domain
SPH21_RS18950	PF13619	KTSC domain
SPH21_RS18970	PF00072	Response regulator receiver domain
SPH21_RS18970	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS18975	PF00072	Response regulator receiver domain
SPH21_RS18975	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS18995	PF00296	Luciferase-like monooxygenase
SPH21_RS19005	PF02543	Carbamoyltransferase N-terminus
SPH21_RS19005	PF16861	Carbamoyltransferase C-terminus
SPH21_RS19015	PF01075	Glycosyltransferase family 9 (heptosyltransferase)
SPH21_RS19020	PF01075	Glycosyltransferase family 9 (heptosyltransferase)
SPH21_RS19025	PF00294	pfkB family carbohydrate kinase
SPH21_RS19025	PF01467	Cytidylyltransferase-like
SPH21_RS19035	PF13580	SIS domain
SPH21_RS19065	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS19065	PF00072	Response regulator receiver domain
SPH21_RS19070	PF00580	UvrD/REP helicase N-terminal domain
SPH21_RS19070	PF13361	UvrD-like helicase C-terminal domain
SPH21_RS19080	PF00107	Zinc-binding dehydrogenase
SPH21_RS19080	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS19085	PF13677	Membrane MotB of proton-channel complex MotA/MotB 
SPH21_RS19085	PF00691	OmpA family
SPH21_RS19095	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS19095	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
SPH21_RS19100	PF00455	DeoR C terminal sensor domain
SPH21_RS19100	PF08220	DeoR-like helix-turn-helix domain
SPH21_RS19105	PF13419	Haloacid dehalogenase-like hydrolase
SPH21_RS19110	PF07690	Major Facilitator Superfamily
SPH21_RS19120	PF13183	4Fe-4S dicluster domain
SPH21_RS19120	PF01565	FAD binding domain 
SPH21_RS19120	PF02913	FAD linked oxidases, C-terminal domain
SPH21_RS19125	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS19125	PF07729	FCD domain
SPH21_RS19130	PF07690	Major Facilitator Superfamily
SPH21_RS19145	PF00999	Sodium/hydrogen exchanger family
SPH21_RS19150	PF00072	Response regulator receiver domain
SPH21_RS19150	PF04397	LytTr DNA-binding domain
SPH21_RS19160	PF18076	Formylglycinamide ribonucleotide amidotransferase N-terminal
SPH21_RS19160	PF18072	Formylglycinamide ribonucleotide amidotransferase linker domain
SPH21_RS19160	PF02769	AIR synthase related protein, C-terminal domain
SPH21_RS19190	PF13476	AAA domain
SPH21_RS19195	PF00149	Calcineurin-like phosphoesterase
SPH21_RS19195	PF12320	Type 5 capsule protein repressor C-terminal domain
SPH21_RS19200	PF01925	Sulfite exporter TauE/SafE
SPH21_RS19210	PF02826	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
SPH21_RS19210	PF00389	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
SPH21_RS19215	PF00313	'Cold-shock' DNA-binding domain
SPH21_RS19220	PF10417	C-terminal domain of 1-Cys peroxiredoxin
SPH21_RS19220	PF00578	AhpC/TSA family
SPH21_RS19230	PF12706	Beta-lactamase superfamily domain
SPH21_RS19230	PF03099	Biotin/lipoate A/B protein ligase family
SPH21_RS19245	PF17854	FtsK alpha domain
SPH21_RS19245	PF09397	Ftsk gamma domain
SPH21_RS19245	PF01580	FtsK/SpoIIIE family
SPH21_RS19245	PF13491	4TM region of DNA translocase FtsK/SpoIIIE
SPH21_RS19255	PF00270	DEAD/DEAH box helicase
SPH21_RS19255	PF00271	Helicase conserved C-terminal domain
SPH21_RS19265	PF07479	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
SPH21_RS19265	PF01210	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
SPH21_RS19270	PF14322	Starch-binding associating with outer membrane
SPH21_RS19270	PF07980	SusD family
SPH21_RS19275	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS19275	PF00593	TonB dependent receptor
SPH21_RS19290	PF00270	DEAD/DEAH box helicase
SPH21_RS19290	PF00271	Helicase conserved C-terminal domain
SPH21_RS19295	PF01979	Amidohydrolase family
SPH21_RS19300	PF02016	LD-carboxypeptidase N-terminal domain
SPH21_RS19300	PF17676	LD-carboxypeptidase C-terminal domain
SPH21_RS19310	PF00877	NlpC/P60 family
SPH21_RS19315	PF01112	Asparaginase
SPH21_RS19320	PF03932	CutC family
SPH21_RS19325	PF02800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
SPH21_RS19325	PF00044	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
SPH21_RS19335	PF00365	Phosphofructokinase
SPH21_RS19350	PF00677	Lumazine binding domain
SPH21_RS19360	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS19370	PF07980	SusD family
SPH21_RS19375	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS19375	PF00593	TonB dependent receptor
SPH21_RS19385	PF01804	Penicillin amidase
SPH21_RS19400	PF00579	tRNA synthetases class I (W and Y)
SPH21_RS19410	PF13520	Amino acid permease
SPH21_RS19415	PF02705	K+ potassium transporter
SPH21_RS19425	PF01557	Fumarylacetoacetate (FAA) hydrolase family
SPH21_RS19430	PF08460	Bacterial SH3 domain
SPH21_RS19430	PF01551	Peptidase family M23
SPH21_RS19435	PF00578	AhpC/TSA family
SPH21_RS19440	PF02779	Transketolase, pyrimidine binding domain
SPH21_RS19440	PF02780	Transketolase, C-terminal domain
SPH21_RS19440	PF00456	Transketolase, thiamine diphosphate binding domain
SPH21_RS19445	PF02779	Transketolase, pyrimidine binding domain
SPH21_RS19445	PF02780	Transketolase, C-terminal domain
SPH21_RS19450	PF04542	Sigma-70 region 2 
SPH21_RS19450	PF08281	Sigma-70, region 4
SPH21_RS19465	PF00202	Aminotransferase class-III
SPH21_RS19470	PF00085	Thioredoxin
SPH21_RS19475	PF07733	Bacterial DNA polymerase III alpha NTPase domain
SPH21_RS19475	PF14579	Helix-hairpin-helix motif
SPH21_RS19475	PF02811	PHP domain
SPH21_RS19475	PF01336	OB-fold nucleic acid binding domain
SPH21_RS19475	PF17657	Bacterial DNA polymerase III alpha subunit finger domain
SPH21_RS19480	PF07495	Y_Y_Y domain
SPH21_RS19480	PF00072	Response regulator receiver domain
SPH21_RS19480	PF07494	Two component regulator propeller
SPH21_RS19480	PF12833	Helix-turn-helix domain
SPH21_RS19480	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS19480	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS19485	PF17137	Domain of unknown function (DUF5110)
SPH21_RS19485	PF16338	Domain of unknown function (DUF4968)
SPH21_RS19485	PF01055	Glycosyl hydrolases family 31 
SPH21_RS19490	PF00593	TonB dependent receptor
SPH21_RS19490	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS19495	PF14322	Starch-binding associating with outer membrane
SPH21_RS19495	PF07980	SusD family
SPH21_RS19530	PF00056	lactate/malate dehydrogenase, NAD binding domain
SPH21_RS19530	PF02866	lactate/malate dehydrogenase, alpha/beta C-terminal domain
SPH21_RS19540	PF13439	Glycosyltransferase Family 4
SPH21_RS19540	PF00534	Glycosyl transferases group 1
SPH21_RS19550	PF00534	Glycosyl transferases group 1
SPH21_RS19550	PF13439	Glycosyltransferase Family 4
SPH21_RS19555	PF03372	Endonuclease/Exonuclease/phosphatase family
SPH21_RS19595	PF00248	Aldo/keto reductase family
SPH21_RS19600	PF01346	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
SPH21_RS19600	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
SPH21_RS19605	PF00232	Glycosyl hydrolase family 1
SPH21_RS19620	PF01966	HD domain
SPH21_RS19620	PF00013	KH domain
SPH21_RS19620	PF12072	Domain of unknown function (DUF3552)
SPH21_RS19635	PF03484	tRNA synthetase B5 domain
SPH21_RS19635	PF17759	Phenylalanyl tRNA synthetase beta chain CLM domain
SPH21_RS19635	PF01588	Putative tRNA binding domain
SPH21_RS19635	PF03483	B3/4 domain
SPH21_RS19635	PF03147	Ferredoxin-fold anticodon binding domain
SPH21_RS19645	PF04002	RadC-like JAB domain
SPH21_RS19655	PF01649	Ribosomal protein S20
SPH21_RS19665	PF00593	TonB dependent receptor
SPH21_RS19665	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS19680	PF02782	FGGY family of carbohydrate kinases, C-terminal domain
SPH21_RS19680	PF00370	FGGY family of carbohydrate kinases, N-terminal domain
SPH21_RS19685	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS19685	PF00532	Periplasmic binding proteins and sugar binding domain of LacI family
SPH21_RS19700	PF00873	AcrB/AcrD/AcrF family
SPH21_RS19705	PF01769	Divalent cation transporter
SPH21_RS19705	PF03448	MgtE intracellular N domain
SPH21_RS19705	PF00571	CBS domain
SPH21_RS19715	PF01740	STAS domain
SPH21_RS19715	PF00916	Sulfate permease family
SPH21_RS19720	PF00484	Carbonic anhydrase
SPH21_RS19725	PF01062	Bestrophin, RFP-TM, chloride channel
SPH21_RS19735	PF00672	HAMP domain
SPH21_RS19735	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS19735	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS19740	PF00072	Response regulator receiver domain
SPH21_RS19740	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS19745	PF00338	Ribosomal protein S10p/S20e
SPH21_RS19750	PF00009	Elongation factor Tu GTP binding domain
SPH21_RS19750	PF03144	Elongation factor Tu domain 2
SPH21_RS19750	PF14492	Elongation Factor G, domain II
SPH21_RS19750	PF00679	Elongation factor G C-terminus
SPH21_RS19750	PF03764	Elongation factor G, domain IV
SPH21_RS19755	PF00177	Ribosomal protein S7p/S5e
SPH21_RS19760	PF00164	Ribosomal protein S12/S23
SPH21_RS19765	PF18030	RimK PreATP-grasp domain
SPH21_RS19765	PF08443	RimK-like ATP-grasp domain
SPH21_RS19780	PF00120	Glutamine synthetase, catalytic domain
SPH21_RS19780	PF12437	Glutamine synthetase type III N terminal 
SPH21_RS19780	PF18318	Glutamine synthetase C-terminal domain
SPH21_RS19785	PF16916	Dimerisation domain of Zinc Transporter
SPH21_RS19785	PF01545	Cation efflux family
SPH21_RS19790	PF00155	Aminotransferase class I and II
SPH21_RS19795	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS19795	PF10518	TAT (twin-arginine translocation) pathway signal sequence
SPH21_RS19805	PF00005	ABC transporter
SPH21_RS19805	PF02687	FtsX-like permease family
SPH21_RS19805	PF12704	MacB-like periplasmic core domain
SPH21_RS19810	PF02547	Queuosine biosynthesis protein
SPH21_RS19815	PF01128	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
SPH21_RS19820	PF01116	Fructose-bisphosphate aldolase class-II
SPH21_RS19825	PF01039	Carboxyl transferase domain
SPH21_RS19825	PF17848	Acetyl-coA carboxylase zinc finger domain
SPH21_RS19830	PF00266	Aminotransferase class-V
SPH21_RS19835	PF02880	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
SPH21_RS19835	PF02878	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
SPH21_RS19835	PF00408	Phosphoglucomutase/phosphomannomutase, C-terminal domain
SPH21_RS19835	PF02879	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
SPH21_RS19845	PF01569	PAP2 superfamily
SPH21_RS19865	PF01121	Dephospho-CoA kinase
SPH21_RS19875	PF02699	Preprotein translocase subunit
SPH21_RS19885	PF01029	NusB family
SPH21_RS19890	PF02812	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
SPH21_RS19890	PF00208	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
SPH21_RS19895	PF00664	ABC transporter transmembrane region
SPH21_RS19895	PF00005	ABC transporter
SPH21_RS19905	PF03167	Uracil DNA glycosylase superfamily
SPH21_RS19910	PF01037	Lrp/AsnC ligand binding domain
SPH21_RS19915	PF02657	Fe-S metabolism associated domain
SPH21_RS19920	PF00266	Aminotransferase class-V
SPH21_RS19925	PF01458	Uncharacterized protein family (UPF0051)
SPH21_RS19930	PF00005	ABC transporter
SPH21_RS19935	PF01458	Uncharacterized protein family (UPF0051)
SPH21_RS19940	PF00215	Orotidine 5'-phosphate decarboxylase / HUMPS family
SPH21_RS19945	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain
SPH21_RS19945	PF07497	Rho termination factor, RNA-binding domain
SPH21_RS19950	PF01066	CDP-alcohol phosphatidyltransferase
SPH21_RS19955	PF01288	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
SPH21_RS19960	PF01343	Peptidase family S49
SPH21_RS19965	PF02811	PHP domain
SPH21_RS19965	PF14716	Helix-hairpin-helix domain
SPH21_RS19965	PF14791	DNA polymerase beta thumb 
SPH21_RS19985	PF01263	Aldose 1-epimerase
SPH21_RS19990	PF05552	Conserved TM helix
SPH21_RS19990	PF00924	Mechanosensitive ion channel
SPH21_RS19995	PF13091	PLD-like domain
SPH21_RS19995	PF13396	Phospholipase_D-nuclease N-terminal
SPH21_RS20015	PF01432	Peptidase family M3
SPH21_RS20045	PF01609	Transposase DDE domain
SPH21_RS20070	PF00072	Response regulator receiver domain
SPH21_RS20070	PF04397	LytTr DNA-binding domain
SPH21_RS20075	PF00072	Response regulator receiver domain
SPH21_RS20075	PF04397	LytTr DNA-binding domain
SPH21_RS20080	PF06580	Histidine kinase
SPH21_RS20080	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS20080	PF07694	5TMR of 5TMR-LYT
SPH21_RS20100	PF04241	Protein of unknown function (DUF423)
SPH21_RS20105	PF00296	Luciferase-like monooxygenase
SPH21_RS20115	PF13419	Haloacid dehalogenase-like hydrolase
SPH21_RS20120	PF03706	Lysylphosphatidylglycerol synthase TM region
SPH21_RS20120	PF09924	Uncharacterised conserved protein (DUF2156)
SPH21_RS20125	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS20125	PF00072	Response regulator receiver domain
SPH21_RS20130	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS20130	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS20130	PF00672	HAMP domain
SPH21_RS20140	PF00873	AcrB/AcrD/AcrF family
SPH21_RS20150	PF00797	N-acetyltransferase
SPH21_RS20160	PF01569	PAP2 superfamily
SPH21_RS20175	PF02566	OsmC-like protein
SPH21_RS20180	PF16874	Glycosyl hydrolase family 36 C-terminal domain
SPH21_RS20180	PF16875	Glycosyl hydrolase family 36 N-terminal domain
SPH21_RS20195	PF00072	Response regulator receiver domain
SPH21_RS20195	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS20225	PF00109	Beta-ketoacyl synthase, N-terminal domain
SPH21_RS20225	PF02801	Beta-ketoacyl synthase, C-terminal domain
SPH21_RS20230	PF01638	HxlR-like helix-turn-helix
SPH21_RS20245	PF00005	ABC transporter
SPH21_RS20255	PF00005	ABC transporter
SPH21_RS20260	PF00005	ABC transporter
SPH21_RS20265	PF13533	Biotin-lipoyl like
SPH21_RS20285	PF01695	IstB-like ATP binding protein
SPH21_RS20290	PF00665	Integrase core domain
SPH21_RS20305	PF00313	'Cold-shock' DNA-binding domain
SPH21_RS20330	PF13533	Biotin-lipoyl like
SPH21_RS20335	PF00664	ABC transporter transmembrane region
SPH21_RS20335	PF03412	Peptidase C39 family
SPH21_RS20335	PF00005	ABC transporter
SPH21_RS20340	PF01757	Acyltransferase family
SPH21_RS20345	PF01734	Patatin-like phospholipase
SPH21_RS20360	PF01906	Putative heavy-metal-binding
SPH21_RS20380	PF04493	Endonuclease V
SPH21_RS20395	PF07690	Major Facilitator Superfamily
SPH21_RS20400	PF16199	Radical_SAM C-terminal domain
SPH21_RS20400	PF04055	Radical SAM superfamily
SPH21_RS20405	PF01370	NAD dependent epimerase/dehydratase family
SPH21_RS20425	PF01979	Amidohydrolase family
SPH21_RS20440	PF02955	Prokaryotic glutathione synthetase, ATP-grasp domain
SPH21_RS20440	PF02951	Prokaryotic glutathione synthetase, N-terminal domain
SPH21_RS20445	PF00970	Oxidoreductase FAD-binding domain
SPH21_RS20445	PF00111	2Fe-2S iron-sulfur cluster binding domain
SPH21_RS20445	PF00175	Oxidoreductase NAD-binding domain 
SPH21_RS20460	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS20460	PF07730	Histidine kinase
SPH21_RS20465	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS20465	PF00072	Response regulator receiver domain
SPH21_RS20470	PF00905	Penicillin binding protein transpeptidase domain
SPH21_RS20470	PF00912	Transglycosylase
SPH21_RS20470	PF06832	Penicillin-Binding Protein C-terminus Family
SPH21_RS20475	PF00207	Alpha-2-macroglobulin family
SPH21_RS20475	PF11974	Bacterial alpha-2-macroglobulin MG3 domain
SPH21_RS20475	PF17972	Bacterial Alpha-2-macroglobulin MG5 domain
SPH21_RS20475	PF17962	Bacterial macroglobulin domain 6
SPH21_RS20475	PF07703	Alpha-2-macroglobulin bait region domain
SPH21_RS20475	PF01835	MG2 domain
SPH21_RS20475	PF17973	Bacterial Alpha-2-macroglobulin MG10 domain
SPH21_RS20485	PF00291	Pyridoxal-phosphate dependent enzyme
SPH21_RS20490	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS20495	PF00724	NADH:flavin oxidoreductase / NADH oxidase family
SPH21_RS20520	PF01926	50S ribosome-binding GTPase
SPH21_RS20520	PF10396	GTP-binding protein TrmE N-terminus
SPH21_RS20520	PF12631	MnmE helical domain
SPH21_RS20540	PF18627	Peptidoglycan GlcNAc deacetylase N-terminal domain
SPH21_RS20540	PF01522	Polysaccharide deacetylase
SPH21_RS20570	PF00285	Citrate synthase, C-terminal domain
SPH21_RS20575	PF03972	MmgE/PrpD family
SPH21_RS20595	PF00083	Sugar (and other) transporter
SPH21_RS20600	PF13181	Tetratricopeptide repeat
SPH21_RS20600	PF17128	Domain of unknown function (DUF5107)
SPH21_RS20605	PF02311	AraC-like ligand binding domain
SPH21_RS20605	PF12833	Helix-turn-helix domain
SPH21_RS20610	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS20610	PF00107	Zinc-binding dehydrogenase
SPH21_RS20650	PF03060	Nitronate monooxygenase
SPH21_RS20660	PF01638	HxlR-like helix-turn-helix
SPH21_RS20670	PF01695	IstB-like ATP binding protein
SPH21_RS20675	PF00665	Integrase core domain
SPH21_RS20720	PF08281	Sigma-70, region 4
SPH21_RS20720	PF04542	Sigma-70 region 2 
SPH21_RS20745	PF00561	alpha/beta hydrolase fold
SPH21_RS20750	PF00106	short chain dehydrogenase
SPH21_RS20780	PF01638	HxlR-like helix-turn-helix
SPH21_RS20795	PF01638	HxlR-like helix-turn-helix
SPH21_RS20800	PF00698	Acyl transferase domain
SPH21_RS20800	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS20800	PF14765	Polyketide synthase dehydratase
SPH21_RS20800	PF16197	Ketoacyl-synthetase C-terminal extension
SPH21_RS20800	PF00550	Phosphopantetheine attachment site
SPH21_RS20800	PF00109	Beta-ketoacyl synthase, N-terminal domain
SPH21_RS20800	PF08659	KR domain
SPH21_RS20800	PF02801	Beta-ketoacyl synthase, C-terminal domain
SPH21_RS20800	PF08990	Erythronolide synthase docking
SPH21_RS20810	PF01613	Flavin reductase like domain
SPH21_RS20820	PF00106	short chain dehydrogenase
SPH21_RS20825	PF01494	FAD binding domain
SPH21_RS20840	PF07730	Histidine kinase
SPH21_RS20840	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS20885	PF01872	RibD C-terminal domain
SPH21_RS20890	PF00884	Sulfatase
SPH21_RS20915	PF04397	LytTr DNA-binding domain
SPH21_RS20915	PF00072	Response regulator receiver domain
SPH21_RS20965	PF00593	TonB dependent receptor
SPH21_RS20965	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS20995	PF16385	Domain of unknown function
SPH21_RS20995	PF00884	Sulfatase
SPH21_RS21020	PF00593	TonB dependent receptor
SPH21_RS21020	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS21025	PF00083	Sugar (and other) transporter
SPH21_RS21030	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS21030	PF07702	UTRA domain
SPH21_RS21035	PF07971	Glycosyl hydrolase family 92
SPH21_RS21035	PF17678	Glycosyl hydrolase family 92 N-terminal domain
SPH21_RS21040	PF14322	Starch-binding associating with outer membrane
SPH21_RS21040	PF07980	SusD family
SPH21_RS21045	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS21045	PF00593	TonB dependent receptor
SPH21_RS21050	PF00403	Heavy-metal-associated domain
SPH21_RS21060	PF03814	Potassium-transporting ATPase A subunit
SPH21_RS21070	PF02669	K+-transporting ATPase, c chain
SPH21_RS21080	PF02702	Osmosensitive K+ channel His kinase sensor domain
SPH21_RS21085	PF16736	Single Cache-like 
SPH21_RS21085	PF00989	PAS fold
SPH21_RS21085	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS21085	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS21090	PF00106	short chain dehydrogenase
SPH21_RS21100	PF00593	TonB dependent receptor
SPH21_RS21100	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS21120	PF00474	Sodium:solute symporter family
SPH21_RS21140	PF00158	Sigma-54 interaction domain
SPH21_RS21140	PF00072	Response regulator receiver domain
SPH21_RS21140	PF02954	Bacterial regulatory protein, Fis family
SPH21_RS21150	PF00211	Adenylate and Guanylate cyclase catalytic domain
SPH21_RS21155	PF01035	6-O-methylguanine DNA methyltransferase, DNA binding domain
SPH21_RS21155	PF02805	Metal binding domain of Ada
SPH21_RS21155	PF12833	Helix-turn-helix domain
SPH21_RS21155	PF02870	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
SPH21_RS21160	PF13195	Protein of unknown function (DUF4011)
SPH21_RS21160	PF13195	Protein of unknown function (DUF4011)
SPH21_RS21160	PF13086	AAA domain
SPH21_RS21160	PF13086	AAA domain
SPH21_RS21160	PF13087	AAA domain
SPH21_RS21160	PF13087	AAA domain
SPH21_RS21165	PF00557	Metallopeptidase family M24
SPH21_RS21170	PF02502	Ribose/Galactose Isomerase
SPH21_RS21175	PF00393	6-phosphogluconate dehydrogenase, C-terminal domain
SPH21_RS21175	PF03446	NAD binding domain of 6-phosphogluconate dehydrogenase
SPH21_RS21180	PF02781	Glucose-6-phosphate dehydrogenase, C-terminal domain
SPH21_RS21180	PF00479	Glucose-6-phosphate dehydrogenase, NAD binding domain
SPH21_RS21185	PF01182	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
SPH21_RS21200	PF01799	[2Fe-2S] binding domain
SPH21_RS21200	PF00111	2Fe-2S iron-sulfur cluster binding domain
SPH21_RS21205	PF02738	Molybdopterin-binding domain of aldehyde dehydrogenase
SPH21_RS21210	PF06964	Alpha-L-arabinofuranosidase C-terminal domain
SPH21_RS21210	PF02018	Carbohydrate binding domain
SPH21_RS21225	PF00083	Sugar (and other) transporter
SPH21_RS21235	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS21235	PF07730	Histidine kinase
SPH21_RS21240	PF07980	SusD family
SPH21_RS21240	PF14322	Starch-binding associating with outer membrane
SPH21_RS21245	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS21245	PF00593	TonB dependent receptor
SPH21_RS21270	PF00571	CBS domain
SPH21_RS21270	PF03448	MgtE intracellular N domain
SPH21_RS21270	PF01769	Divalent cation transporter
SPH21_RS21275	PF00081	Iron/manganese superoxide dismutases, alpha-hairpin domain
SPH21_RS21275	PF02777	Iron/manganese superoxide dismutases, C-terminal domain
SPH21_RS21285	PF02630	SCO1/SenC
SPH21_RS21330	PF00593	TonB dependent receptor
SPH21_RS21330	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS21355	PF12704	MacB-like periplasmic core domain
SPH21_RS21355	PF02687	FtsX-like permease family
SPH21_RS21360	PF00884	Sulfatase
SPH21_RS21365	PF02525	Flavodoxin-like fold
SPH21_RS21375	PF04542	Sigma-70 region 2 
SPH21_RS21375	PF08281	Sigma-70, region 4
SPH21_RS21380	PF00884	Sulfatase
SPH21_RS21380	PF16347	Domain of unknown function (DUF4976)
SPH21_RS21395	PF02525	Flavodoxin-like fold
SPH21_RS21405	PF00135	Carboxylesterase family
SPH21_RS21430	PF02852	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
SPH21_RS21430	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS21450	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS21450	PF00593	TonB dependent receptor
SPH21_RS21480	PF12833	Helix-turn-helix domain
SPH21_RS21495	PF02311	AraC-like ligand binding domain
SPH21_RS21495	PF12833	Helix-turn-helix domain
SPH21_RS21510	PF03466	LysR substrate binding domain
SPH21_RS21510	PF00126	Bacterial regulatory helix-turn-helix protein, lysR family
SPH21_RS21515	PF00561	alpha/beta hydrolase fold
SPH21_RS21540	PF00106	short chain dehydrogenase
SPH21_RS21555	PF17755	UvrA DNA-binding domain
SPH21_RS21555	PF17760	UvrA interaction domain
SPH21_RS21555	PF00005	ABC transporter
SPH21_RS21580	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS21615	PF00117	Glutamine amidotransferase class-I
SPH21_RS21615	PF13673	Acetyltransferase (GNAT) domain
SPH21_RS21615	PF13302	Acetyltransferase (GNAT) domain
SPH21_RS21615	PF00958	GMP synthase C terminal domain
SPH21_RS21615	PF03352	Methyladenine glycosylase
SPH21_RS21655	PF00106	short chain dehydrogenase
SPH21_RS21660	PF06580	Histidine kinase
SPH21_RS21660	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS21660	PF07694	5TMR of 5TMR-LYT
SPH21_RS21665	PF04397	LytTr DNA-binding domain
SPH21_RS21665	PF00072	Response regulator receiver domain
SPH21_RS21695	PF00881	Nitroreductase family
SPH21_RS21700	PF01638	HxlR-like helix-turn-helix
SPH21_RS21720	PF12704	MacB-like periplasmic core domain
SPH21_RS21720	PF02687	FtsX-like permease family
SPH21_RS21720	PF00005	ABC transporter
SPH21_RS21750	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS21760	PF01458	Uncharacterized protein family (UPF0051)
SPH21_RS21770	PF00106	short chain dehydrogenase
SPH21_RS21800	PF01850	PIN domain
SPH21_RS21805	PF01624	MutS domain I
SPH21_RS21805	PF05192	MutS domain III
SPH21_RS21805	PF05190	MutS family domain IV
SPH21_RS21805	PF00488	MutS domain V
SPH21_RS21805	PF05188	MutS domain II
SPH21_RS21825	PF13808	DDE_Tnp_1-associated
SPH21_RS21825	PF01609	Transposase DDE domain
SPH21_RS21840	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS21840	PF00593	TonB dependent receptor
SPH21_RS21845	PF07980	SusD family
SPH21_RS21845	PF14322	Starch-binding associating with outer membrane
SPH21_RS21855	PF02652	L-lactate permease
SPH21_RS21860	PF07470	Glycosyl Hydrolase Family 88
SPH21_RS21870	PF01695	IstB-like ATP binding protein
SPH21_RS21875	PF00665	Integrase core domain
SPH21_RS21930	PF00005	ABC transporter
SPH21_RS21935	PF00005	ABC transporter
SPH21_RS21935	PF00664	ABC transporter transmembrane region
SPH21_RS21935	PF04954	Siderophore-interacting protein
SPH21_RS21935	PF08021	Siderophore-interacting FAD-binding domain
SPH21_RS22000	PF12833	Helix-turn-helix domain
SPH21_RS22000	PF01965	DJ-1/PfpI family
SPH21_RS22010	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS22010	PF00703	Glycosyl hydrolases family 2
SPH21_RS22010	PF16355	Domain of unknown function (DUF4982)
SPH21_RS22010	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS22030	PF01638	HxlR-like helix-turn-helix
SPH21_RS22055	PF04616	Glycosyl hydrolases family 43
SPH21_RS22070	PF04616	Glycosyl hydrolases family 43
SPH21_RS22070	PF05270	Alpha-L-arabinofuranosidase B (ABFB) domain
SPH21_RS22075	PF16385	Domain of unknown function
SPH21_RS22075	PF00884	Sulfatase
SPH21_RS22085	PF00593	TonB dependent receptor
SPH21_RS22085	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS22135	PF00072	Response regulator receiver domain
SPH21_RS22135	PF04397	LytTr DNA-binding domain
SPH21_RS22145	PF00313	'Cold-shock' DNA-binding domain
SPH21_RS22150	PF04545	Sigma-70, region 4
SPH21_RS22150	PF04539	Sigma-70 region 3
SPH21_RS22150	PF03979	Sigma-70 factor, region 1.1
SPH21_RS22150	PF04542	Sigma-70 region 2 
SPH21_RS22150	PF00140	Sigma-70 factor, region 1.2
SPH21_RS22175	PF00302	Chloramphenicol acetyltransferase
SPH21_RS22190	PF09335	SNARE associated Golgi protein
SPH21_RS22195	PF06580	Histidine kinase
SPH21_RS22195	PF07694	5TMR of 5TMR-LYT
SPH21_RS22205	PF00072	Response regulator receiver domain
SPH21_RS22205	PF04397	LytTr DNA-binding domain
SPH21_RS22215	PF00106	short chain dehydrogenase
SPH21_RS22225	PF00150	Cellulase (glycosyl hydrolase family 5)
SPH21_RS22225	PF14600	Cellulose-binding domain
SPH21_RS22235	PF08543	Phosphomethylpyrimidine kinase
SPH21_RS22235	PF02581	Thiamine monophosphate synthase
SPH21_RS22240	PF00703	Glycosyl hydrolases family 2
SPH21_RS22240	PF16353	Domain of unknown function(DUF4981)
SPH21_RS22240	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS22240	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS22240	PF02929	Beta galactosidase small chain
SPH21_RS22255	PF07730	Histidine kinase
SPH21_RS22255	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS22255	PF05384	Sensor protein DegS
SPH21_RS22315	PF02311	AraC-like ligand binding domain
SPH21_RS22315	PF12833	Helix-turn-helix domain
SPH21_RS22335	PF03372	Endonuclease/Exonuclease/phosphatase family
SPH21_RS22340	PF08534	Redoxin
SPH21_RS22370	PF00732	GMC oxidoreductase
SPH21_RS22370	PF05199	GMC oxidoreductase
SPH21_RS22375	PF00005	ABC transporter
SPH21_RS22380	PF00528	Binding-protein-dependent transport system inner membrane component
SPH21_RS22385	PF00528	Binding-protein-dependent transport system inner membrane component
SPH21_RS22390	PF12849	PBP superfamily domain
SPH21_RS22410	PF03180	NLPA lipoprotein
SPH21_RS22415	PF00528	Binding-protein-dependent transport system inner membrane component
SPH21_RS22420	PF00005	ABC transporter
SPH21_RS22420	PF09383	NIL domain
SPH21_RS22425	PF00144	Beta-lactamase
SPH21_RS22430	PF00326	Prolyl oligopeptidase family
SPH21_RS22430	PF07676	WD40-like Beta Propeller Repeat
SPH21_RS22440	PF00593	TonB dependent receptor
SPH21_RS22440	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS22445	PF02733	Dak1 domain
SPH21_RS22445	PF02734	DAK2 domain
SPH21_RS22460	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS22490	PF07690	Major Facilitator Superfamily
SPH21_RS22495	PF00370	FGGY family of carbohydrate kinases, N-terminal domain
SPH21_RS22495	PF02782	FGGY family of carbohydrate kinases, C-terminal domain
SPH21_RS22515	PF00884	Sulfatase
SPH21_RS22515	PF16385	Domain of unknown function
SPH21_RS22520	PF00296	Luciferase-like monooxygenase
SPH21_RS22530	PF07971	Glycosyl hydrolase family 92
SPH21_RS22530	PF17678	Glycosyl hydrolase family 92 N-terminal domain
SPH21_RS22555	PF17678	Glycosyl hydrolase family 92 N-terminal domain
SPH21_RS22555	PF07971	Glycosyl hydrolase family 92
SPH21_RS22560	PF00703	Glycosyl hydrolases family 2
SPH21_RS22560	PF02837	Glycosyl hydrolases family 2, sugar binding domain
SPH21_RS22560	PF16355	Domain of unknown function (DUF4982)
SPH21_RS22560	PF18565	Glycoside hydrolase family 2 C-terminal domain 5
SPH21_RS22560	PF02836	Glycosyl hydrolases family 2, TIM barrel domain
SPH21_RS22580	PF12697	Alpha/beta hydrolase family
SPH21_RS22585	PF00166	Chaperonin 10 Kd subunit
SPH21_RS22600	PF07995	Glucose / Sorbosone dehydrogenase
SPH21_RS22610	PF04264	YceI-like domain
SPH21_RS22615	PF01081	KDPG and KHG aldolase
SPH21_RS22620	PF13378	Enolase C-terminal domain-like
SPH21_RS22620	PF02746	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
SPH21_RS22625	PF07690	Major Facilitator Superfamily
SPH21_RS22630	PF05035	2-keto-3-deoxy-galactonokinase
SPH21_RS22635	PF07690	Major Facilitator Superfamily
SPH21_RS22640	PF01344	Kelch motif
SPH21_RS22645	PF00701	Dihydrodipicolinate synthetase family
SPH21_RS22650	PF10633	NPCBM-associated, NEW3 domain of alpha-galactosidase
SPH21_RS22650	PF13088	BNR repeat-like domain
SPH21_RS22650	PF00754	F5/8 type C domain
SPH21_RS22660	PF04650	YSIRK type signal peptide
SPH21_RS22660	PF02973	Sialidase, N-terminal domain
SPH21_RS22660	PF13088	BNR repeat-like domain
SPH21_RS22665	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS22665	PF00155	Aminotransferase class I and II
SPH21_RS22740	PF12823	Domain of unknown function (DUF3817)
SPH21_RS22755	PF00557	Metallopeptidase family M24
SPH21_RS22760	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS22775	PF07992	Pyridine nucleotide-disulphide oxidoreductase
SPH21_RS22790	PF00561	alpha/beta hydrolase fold
SPH21_RS22795	PF02311	AraC-like ligand binding domain
SPH21_RS22795	PF12833	Helix-turn-helix domain
SPH21_RS22800	PF01609	Transposase DDE domain
SPH21_RS22825	PF00436	Single-strand binding protein family
SPH21_RS22840	PF02595	Glycerate kinase family
SPH21_RS22845	PF00873	AcrB/AcrD/AcrF family
SPH21_RS22860	PF00440	Bacterial regulatory proteins, tetR family
SPH21_RS22860	PF08359	YsiA-like protein, C-terminal region
SPH21_RS22865	PF01431	Peptidase family M13
SPH21_RS22865	PF05649	Peptidase family M13
SPH21_RS22870	PF00291	Pyridoxal-phosphate dependent enzyme
SPH21_RS22875	PF01609	Transposase DDE domain
SPH21_RS22875	PF13808	DDE_Tnp_1-associated
SPH21_RS22880	PF06580	Histidine kinase
SPH21_RS22885	PF00072	Response regulator receiver domain
SPH21_RS22885	PF04397	LytTr DNA-binding domain
SPH21_RS22915	PF00753	Metallo-beta-lactamase superfamily
SPH21_RS22915	PF16123	Hydroxyacylglutathione hydrolase C-terminus
SPH21_RS22920	PF01266	FAD dependent oxidoreductase
SPH21_RS22920	PF05430	S-adenosyl-L-methionine-dependent methyltransferase
SPH21_RS22930	PF01053	Cys/Met metabolism PLP-dependent enzyme
SPH21_RS22935	PF09180	Prolyl-tRNA synthetase, C-terminal
SPH21_RS22935	PF00587	tRNA synthetase class II core domain (G, H, P, S and T)
SPH21_RS22935	PF03129	Anticodon binding domain
SPH21_RS22985	PF00210	Ferritin-like domain
SPH21_RS22990	PF01957	NfeD-like C-terminal, partner-binding
SPH21_RS22990	PF01972	Serine dehydrogenase proteinase
SPH21_RS23000	PF01476	LysM domain
SPH21_RS23000	PF00877	NlpC/P60 family
SPH21_RS23005	PF00485	Phosphoribulokinase / Uridine kinase family
SPH21_RS23010	PF01144	Coenzyme A transferase
SPH21_RS23020	PF01144	Coenzyme A transferase
SPH21_RS23025	PF00488	MutS domain V
SPH21_RS23025	PF01713	Smr domain
SPH21_RS23035	PF01168	Alanine racemase, N-terminal domain
SPH21_RS23050	PF00696	Amino acid kinase family
SPH21_RS23050	PF01842	ACT domain
SPH21_RS23065	PF00842	Alanine racemase, C-terminal domain
SPH21_RS23065	PF01168	Alanine racemase, N-terminal domain
SPH21_RS23090	PF02627	Carboxymuconolactone decarboxylase family
SPH21_RS23115	PF00313	'Cold-shock' DNA-binding domain
SPH21_RS23130	PF02627	Carboxymuconolactone decarboxylase family
SPH21_RS23165	PF00593	TonB dependent receptor
SPH21_RS23165	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS23170	PF14322	Starch-binding associating with outer membrane
SPH21_RS23170	PF07980	SusD family
SPH21_RS23175	PF07470	Glycosyl Hydrolase Family 88
SPH21_RS23185	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS23185	PF13823	Alcohol dehydrogenase GroES-associated
SPH21_RS23185	PF00107	Zinc-binding dehydrogenase
SPH21_RS23210	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS23210	PF00593	TonB dependent receptor
SPH21_RS23215	PF14322	Starch-binding associating with outer membrane
SPH21_RS23215	PF07980	SusD family
SPH21_RS23225	PF07944	Beta-L-arabinofuranosidase, GH127
SPH21_RS23230	PF00155	Aminotransferase class I and II
SPH21_RS23230	PF00392	Bacterial regulatory proteins, gntR family
SPH21_RS23240	PF00550	Phosphopantetheine attachment site
SPH21_RS23240	PF07993	Male sterility protein
SPH21_RS23240	PF00668	Condensation domain
SPH21_RS23240	PF13193	AMP-binding enzyme C-terminal domain
SPH21_RS23240	PF00501	AMP-binding enzyme
SPH21_RS23255	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS23255	PF00072	Response regulator receiver domain
SPH21_RS23260	PF00174	Oxidoreductase molybdopterin binding domain
SPH21_RS23280	PF14322	Starch-binding associating with outer membrane
SPH21_RS23280	PF07980	SusD family
SPH21_RS23285	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS23285	PF00593	TonB dependent receptor
SPH21_RS23300	PF00709	Adenylosuccinate synthetase
SPH21_RS23325	PF00072	Response regulator receiver domain
SPH21_RS23325	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS23330	PF00149	Calcineurin-like phosphoesterase
SPH21_RS23335	PF00005	ABC transporter
SPH21_RS23340	PF00528	Binding-protein-dependent transport system inner membrane component
SPH21_RS23345	PF00528	Binding-protein-dependent transport system inner membrane component
SPH21_RS23355	PF00072	Response regulator receiver domain
SPH21_RS23355	PF00990	Diguanylate cyclase, GGDEF domain
SPH21_RS23360	PF13426	PAS domain
SPH21_RS23360	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS23360	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS23360	PF00672	HAMP domain
SPH21_RS23390	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS23390	PF07694	5TMR of 5TMR-LYT
SPH21_RS23390	PF13492	GAF domain
SPH21_RS23390	PF06580	Histidine kinase
SPH21_RS23395	PF04397	LytTr DNA-binding domain
SPH21_RS23395	PF00072	Response regulator receiver domain
SPH21_RS23400	PF02525	Flavodoxin-like fold
SPH21_RS23410	PF00593	TonB dependent receptor
SPH21_RS23410	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS23430	PF04224	Protein of unknown function, DUF417
SPH21_RS23435	PF02311	AraC-like ligand binding domain
SPH21_RS23435	PF12833	Helix-turn-helix domain
SPH21_RS23440	PF00111	2Fe-2S iron-sulfur cluster binding domain
SPH21_RS23440	PF01799	[2Fe-2S] binding domain
SPH21_RS23450	PF02738	Molybdopterin-binding domain of aldehyde dehydrogenase
SPH21_RS23450	PF13442	Cytochrome C oxidase, cbb3-type, subunit III 
SPH21_RS23450	PF00034	Cytochrome c
SPH21_RS23460	PF00578	AhpC/TSA family
SPH21_RS23465	PF00578	AhpC/TSA family
SPH21_RS23470	PF00593	TonB dependent receptor
SPH21_RS23470	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS23475	PF14322	Starch-binding associating with outer membrane
SPH21_RS23475	PF07980	SusD family
SPH21_RS23480	PF00884	Sulfatase
SPH21_RS23480	PF16385	Domain of unknown function
SPH21_RS23495	PF00106	short chain dehydrogenase
SPH21_RS23505	PF12464	Maltose acetyltransferase 
SPH21_RS23505	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS23515	PF00106	short chain dehydrogenase
SPH21_RS23535	PF00248	Aldo/keto reductase family
SPH21_RS23565	PF01758	Sodium Bile acid symporter family
SPH21_RS23570	PF01451	Low molecular weight phosphotyrosine protein phosphatase
SPH21_RS23590	PF00251	Glycosyl hydrolases family 32 N-terminal domain
SPH21_RS23590	PF08244	Glycosyl hydrolases family 32 C terminal
SPH21_RS23595	PF00294	pfkB family carbohydrate kinase
SPH21_RS23605	PF08240	Alcohol dehydrogenase GroES-like domain
SPH21_RS23605	PF00107	Zinc-binding dehydrogenase
SPH21_RS23610	PF02311	AraC-like ligand binding domain
SPH21_RS23610	PF12833	Helix-turn-helix domain
SPH21_RS23615	PF01638	HxlR-like helix-turn-helix
SPH21_RS23625	PF01370	NAD dependent epimerase/dehydratase family
SPH21_RS23630	PF01965	DJ-1/PfpI family
SPH21_RS23630	PF12833	Helix-turn-helix domain
SPH21_RS23635	PF00083	Sugar (and other) transporter
SPH21_RS23655	PF00593	TonB dependent receptor
SPH21_RS23655	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS23660	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS23665	PF16767	Sensor domain of alginate biosynthesis sensor protein KinB
SPH21_RS23665	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS23665	PF08448	PAS fold
SPH21_RS23665	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS23665	PF00672	HAMP domain
SPH21_RS23680	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS23680	PF00593	TonB dependent receptor
SPH21_RS23715	PF13673	Acetyltransferase (GNAT) domain
SPH21_RS23715	PF00583	Acetyltransferase (GNAT) family
SPH21_RS23745	PF00072	Response regulator receiver domain
SPH21_RS23745	PF04397	LytTr DNA-binding domain
SPH21_RS23750	PF02661	Fic/DOC family
SPH21_RS23750	PF12728	Helix-turn-helix domain
SPH21_RS23760	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS23760	PF07730	Histidine kinase
SPH21_RS23760	PF05231	MASE1
SPH21_RS23765	PF01638	HxlR-like helix-turn-helix
SPH21_RS23770	PF00561	alpha/beta hydrolase fold
SPH21_RS23770	PF08386	TAP-like protein
SPH21_RS23775	PF00165	Bacterial regulatory helix-turn-helix proteins, AraC family
SPH21_RS23785	PF12706	Beta-lactamase superfamily domain
SPH21_RS23815	PF00072	Response regulator receiver domain
SPH21_RS23815	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS23820	PF07495	Y_Y_Y domain
SPH21_RS23820	PF00072	Response regulator receiver domain
SPH21_RS23820	PF12833	Helix-turn-helix domain
SPH21_RS23820	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS23820	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS23820	PF07494	Two component regulator propeller
SPH21_RS23885	PF07724	AAA domain (Cdc48 subfamily)
SPH21_RS23885	PF02861	Clp amino terminal domain, pathogenicity island component
SPH21_RS23885	PF17871	AAA lid domain
SPH21_RS23885	PF00004	ATPase family associated with various cellular activities (AAA)
SPH21_RS23885	PF10431	C-terminal, D2-small domain, of ClpB protein 
SPH21_RS23920	PF00958	GMP synthase C terminal domain
SPH21_RS23920	PF00117	Glutamine amidotransferase class-I
SPH21_RS23920	PF03352	Methyladenine glycosylase
SPH21_RS23920	PF13302	Acetyltransferase (GNAT) domain
SPH21_RS23920	PF13673	Acetyltransferase (GNAT) domain
SPH21_RS23945	PF00724	NADH:flavin oxidoreductase / NADH oxidase family
SPH21_RS23970	PF00593	TonB dependent receptor
SPH21_RS23970	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS23975	PF07980	SusD family
SPH21_RS23975	PF14322	Starch-binding associating with outer membrane
SPH21_RS23990	PF13533	Biotin-lipoyl like
SPH21_RS24000	PF12833	Helix-turn-helix domain
SPH21_RS24000	PF02311	AraC-like ligand binding domain
SPH21_RS24005	PF02525	Flavodoxin-like fold
SPH21_RS24010	PF06445	GyrI-like small molecule binding domain
SPH21_RS24010	PF12833	Helix-turn-helix domain
SPH21_RS24015	PF00106	short chain dehydrogenase
SPH21_RS24030	PF02627	Carboxymuconolactone decarboxylase family
SPH21_RS24070	PF00293	NUDIX domain
SPH21_RS24075	PF00158	Sigma-54 interaction domain
SPH21_RS24075	PF01590	GAF domain
SPH21_RS24090	PF04397	LytTr DNA-binding domain
SPH21_RS24090	PF00072	Response regulator receiver domain
SPH21_RS24095	PF00158	Sigma-54 interaction domain
SPH21_RS24095	PF01590	GAF domain
SPH21_RS24100	PF00199	Catalase
SPH21_RS24100	PF06628	Catalase-related immune-responsive
SPH21_RS24105	PF07859	alpha/beta hydrolase fold
SPH21_RS24110	PF00158	Sigma-54 interaction domain
SPH21_RS24110	PF01590	GAF domain
SPH21_RS24115	PF07859	alpha/beta hydrolase fold
SPH21_RS24120	PF01638	HxlR-like helix-turn-helix
SPH21_RS24140	PF12833	Helix-turn-helix domain
SPH21_RS24150	PF02321	Outer membrane efflux protein
SPH21_RS24155	PF00873	AcrB/AcrD/AcrF family
SPH21_RS24160	PF00529	HlyD membrane-fusion protein of T1SS
SPH21_RS24160	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
SPH21_RS24170	PF02311	AraC-like ligand binding domain
SPH21_RS24170	PF12833	Helix-turn-helix domain
SPH21_RS24175	PF00072	Response regulator receiver domain
SPH21_RS24175	PF00196	Bacterial regulatory proteins, luxR family
SPH21_RS24250	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS24250	PF00593	TonB dependent receptor
SPH21_RS24255	PF00578	AhpC/TSA family
SPH21_RS24280	PF07693	KAP family P-loop domain
SPH21_RS24345	PF02874	ATP synthase alpha/beta family, beta-barrel domain
SPH21_RS24345	PF00306	ATP synthase alpha/beta chain, C terminal domain
SPH21_RS24345	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain
SPH21_RS24360	PF01695	IstB-like ATP binding protein
SPH21_RS24365	PF00665	Integrase core domain
SPH21_RS24375	PF00069	Protein kinase domain
SPH21_RS24400	PF01695	IstB-like ATP binding protein
SPH21_RS24405	PF00665	Integrase core domain
SPH21_RS24510	PF01609	Transposase DDE domain
SPH21_RS24530	PF02687	FtsX-like permease family
SPH21_RS24530	PF12704	MacB-like periplasmic core domain
SPH21_RS24560	PF12833	Helix-turn-helix domain
SPH21_RS24560	PF02311	AraC-like ligand binding domain
SPH21_RS24565	PF00106	short chain dehydrogenase
SPH21_RS24570	PF00106	short chain dehydrogenase
SPH21_RS24580	PF00561	alpha/beta hydrolase fold
SPH21_RS24600	PF00106	short chain dehydrogenase
SPH21_RS24610	PF00583	Acetyltransferase (GNAT) family
SPH21_RS24620	PF12399	Branched-chain amino acid ATP-binding cassette transporter
SPH21_RS24620	PF00005	ABC transporter
SPH21_RS24625	PF01613	Flavin reductase like domain
SPH21_RS24635	PF12833	Helix-turn-helix domain
SPH21_RS24645	PF01638	HxlR-like helix-turn-helix
SPH21_RS24650	PF07690	Major Facilitator Superfamily
SPH21_RS24665	PF00248	Aldo/keto reductase family
SPH21_RS24680	PF01638	HxlR-like helix-turn-helix
SPH21_RS24705	PF01546	Peptidase family M20/M25/M40
SPH21_RS24720	PF00593	TonB dependent receptor
SPH21_RS24720	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS24735	PF01661	Macro domain
SPH21_RS24755	PF01022	Bacterial regulatory protein, arsR family
SPH21_RS24785	PF12704	MacB-like periplasmic core domain
SPH21_RS24785	PF00005	ABC transporter
SPH21_RS24785	PF02687	FtsX-like permease family
SPH21_RS24790	PF01757	Acyltransferase family
SPH21_RS24805	PF01139	tRNA-splicing ligase RtcB
SPH21_RS24830	PF03150	Di-haem cytochrome c peroxidase
SPH21_RS24835	PF03797	Autotransporter beta-domain
SPH21_RS24855	PF01965	DJ-1/PfpI family
SPH21_RS24855	PF12833	Helix-turn-helix domain
SPH21_RS24880	PF00296	Luciferase-like monooxygenase
SPH21_RS24905	PF00884	Sulfatase
SPH21_RS24905	PF16385	Domain of unknown function
SPH21_RS24915	PF07980	SusD family
SPH21_RS24915	PF14322	Starch-binding associating with outer membrane
SPH21_RS24920	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS24920	PF00593	TonB dependent receptor
SPH21_RS24925	PF00884	Sulfatase
SPH21_RS24930	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS24930	PF00072	Response regulator receiver domain
SPH21_RS24930	PF07494	Two component regulator propeller
SPH21_RS24930	PF12833	Helix-turn-helix domain
SPH21_RS24930	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS24930	PF07495	Y_Y_Y domain
SPH21_RS24930	PF00072	Response regulator receiver domain
SPH21_RS24930	PF07494	Two component regulator propeller
SPH21_RS24930	PF12833	Helix-turn-helix domain
SPH21_RS24930	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS24930	PF07495	Y_Y_Y domain
SPH21_RS24930	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS24945	PF00593	TonB dependent receptor
SPH21_RS24945	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS24955	PF08003	Protein of unknown function (DUF1698)
SPH21_RS25000	PF00199	Catalase
SPH21_RS25000	PF18011	C-terminal domain found in long catalases
SPH21_RS25000	PF06628	Catalase-related immune-responsive
SPH21_RS25005	PF05974	Domain of unknown function (DUF892)
SPH21_RS25040	PF14322	Starch-binding associating with outer membrane
SPH21_RS25040	PF07980	SusD family
SPH21_RS25045	PF00593	TonB dependent receptor
SPH21_RS25045	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS25055	PF12833	Helix-turn-helix domain
SPH21_RS25055	PF01965	DJ-1/PfpI family
SPH21_RS25060	PF00044	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
SPH21_RS25060	PF02800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
SPH21_RS25065	PF01575	MaoC like domain
SPH21_RS25080	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
SPH21_RS25085	PF08713	DNA alkylation repair enzyme
SPH21_RS25115	PF01047	MarR family
SPH21_RS25125	PF04299	Putative FMN-binding domain
SPH21_RS25130	PF01658	Myo-inositol-1-phosphate synthase
SPH21_RS25135	PF00593	TonB dependent receptor
SPH21_RS25135	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS25145	PF05970	PIF1-like helicase
SPH21_RS25145	PF14493	Helix-turn-helix domain
SPH21_RS25150	PF05192	MutS domain III
SPH21_RS25150	PF01624	MutS domain I
SPH21_RS25150	PF00488	MutS domain V
SPH21_RS25150	PF05188	MutS domain II
SPH21_RS25150	PF05190	MutS family domain IV
SPH21_RS25155	PF00230	Major intrinsic protein
SPH21_RS25165	PF09859	Oxygenase, catalysing oxidative methylation of damaged DNA
SPH21_RS25170	PF00730	HhH-GPD superfamily base excision DNA repair protein
SPH21_RS25170	PF07934	8-oxoguanine DNA glycosylase, N-terminal domain
SPH21_RS25180	PF02685	Glucokinase
SPH21_RS25190	PF02441	Flavoprotein
SPH21_RS25195	PF00356	Bacterial regulatory proteins, lacI family
SPH21_RS25200	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS25200	PF00593	TonB dependent receptor
SPH21_RS25205	PF14322	Starch-binding associating with outer membrane
SPH21_RS25205	PF07980	SusD family
SPH21_RS25210	PF00593	TonB dependent receptor
SPH21_RS25210	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS25215	PF07980	SusD family
SPH21_RS25220	PF02447	GntP family permease
SPH21_RS25235	PF09962	Uncharacterized conserved protein (DUF2196)
SPH21_RS25245	PF13426	PAS domain
SPH21_RS25245	PF01740	STAS domain
SPH21_RS25250	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS25250	PF00072	Response regulator receiver domain
SPH21_RS25255	PF00535	Glycosyl transferase family 2
SPH21_RS25260	PF00535	Glycosyl transferase family 2
SPH21_RS25275	PF01979	Amidohydrolase family
SPH21_RS25280	PF00483	Nucleotidyl transferase
SPH21_RS25285	PF00534	Glycosyl transferases group 1
SPH21_RS25285	PF08323	Starch synthase catalytic domain
SPH21_RS25290	PF02922	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
SPH21_RS25290	PF00128	Alpha amylase, catalytic domain
SPH21_RS25290	PF02806	Alpha amylase, C-terminal all-beta domain
SPH21_RS25295	PF16338	Domain of unknown function (DUF4968)
SPH21_RS25295	PF17137	Domain of unknown function (DUF5110)
SPH21_RS25295	PF13802	Galactose mutarotase-like
SPH21_RS25295	PF01055	Glycosyl hydrolases family 31 
SPH21_RS25305	PF01634	ATP phosphoribosyltransferase
SPH21_RS25305	PF08029	HisG, C-terminal domain
SPH21_RS25310	PF00815	Histidinol dehydrogenase
SPH21_RS25315	PF00155	Aminotransferase class I and II
SPH21_RS25320	PF00475	Imidazoleglycerol-phosphate dehydratase
SPH21_RS25325	PF00117	Glutamine amidotransferase class-I
SPH21_RS25330	PF00977	Histidine biosynthesis protein
SPH21_RS25335	PF00977	Histidine biosynthesis protein
SPH21_RS25340	PF01502	Phosphoribosyl-AMP cyclohydrolase
SPH21_RS25340	PF01503	Phosphoribosyl-ATP pyrophosphohydrolase
SPH21_RS25360	PF03960	ArsC family
SPH21_RS25365	PF01195	Peptidyl-tRNA hydrolase
SPH21_RS25370	PF14693	Ribosomal protein TL5, C-terminal domain
SPH21_RS25370	PF01386	Ribosomal L25p family
SPH21_RS25375	PF13793	N-terminal domain of ribose phosphate pyrophosphokinase
SPH21_RS25375	PF14572	Phosphoribosyl synthetase-associated domain
SPH21_RS25410	PF00106	short chain dehydrogenase
SPH21_RS25420	PF00436	Single-strand binding protein family
SPH21_RS25435	PF03449	Transcription elongation factor, N-terminal
SPH21_RS25435	PF01272	Transcription elongation factor, GreA/GreB, C-term
SPH21_RS25455	PF07715	TonB-dependent Receptor Plug Domain
SPH21_RS25455	PF00593	TonB dependent receptor
SPH21_RS25460	PF07980	SusD family
SPH21_RS25460	PF14322	Starch-binding associating with outer membrane
SPH21_RS25465	PF00884	Sulfatase
SPH21_RS25470	PF13859	BNR repeat-like domain
SPH21_RS25470	PF14873	N-terminal domain of BNR-repeat neuraminidase
SPH21_RS25475	PF02684	Lipid-A-disaccharide synthetase
SPH21_RS25485	PF01975	Survival protein SurE
SPH21_RS25490	PF05532	CsbD-like
SPH21_RS25495	PF16177	Acetyl-coenzyme A synthetase N-terminus
SPH21_RS25495	PF00501	AMP-binding enzyme
SPH21_RS25495	PF13193	AMP-binding enzyme C-terminal domain
SPH21_RS25505	PF00083	Sugar (and other) transporter
SPH21_RS25510	PF00830	Ribosomal L28 family
SPH21_RS25515	PF00471	Ribosomal protein L33
SPH21_RS25525	PF02881	SRP54-type protein, helical bundle domain
SPH21_RS25525	PF00448	SRP54-type protein, GTPase domain
SPH21_RS25530	PF18693	TRAM domain
SPH21_RS25530	PF04055	Radical SAM superfamily
SPH21_RS25530	PF00919	Uncharacterized protein family UPF0004
SPH21_RS25535	PF10079	Bacillithiol biosynthesis BshC 
SPH21_RS25550	PF03653	Uncharacterised protein family (UPF0093)
SPH21_RS25555	PF01208	Uroporphyrinogen decarboxylase (URO-D)
SPH21_RS25565	PF00072	Response regulator receiver domain
SPH21_RS25565	PF00486	Transcriptional regulatory protein, C terminal
SPH21_RS25570	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS25570	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS25570	PF16736	Single Cache-like 
SPH21_RS25570	PF00989	PAS fold
SPH21_RS25575	PF00202	Aminotransferase class-III
SPH21_RS25580	PF00490	Delta-aminolevulinic acid dehydratase
SPH21_RS25585	PF03900	Porphobilinogen deaminase, C-terminal domain
SPH21_RS25585	PF01379	Porphobilinogen deaminase, dipyromethane cofactor binding domain
SPH21_RS25590	PF01488	Shikimate / quinate 5-dehydrogenase
SPH21_RS25590	PF00745	Glutamyl-tRNAGlu reductase, dimerisation domain
SPH21_RS25590	PF05201	Glutamyl-tRNAGlu reductase, N-terminal domain
SPH21_RS25605	PF07244	Surface antigen variable number repeat
SPH21_RS25605	PF01103	Surface antigen
SPH21_RS25610	PF01255	Putative undecaprenyl diphosphate synthase
SPH21_RS25620	PF01513	ATP-NAD kinase
SPH21_RS25625	PF00478	IMP dehydrogenase / GMP reductase domain
SPH21_RS25625	PF00571	CBS domain
SPH21_RS25630	PF08386	TAP-like protein
SPH21_RS25630	PF00561	alpha/beta hydrolase fold
SPH21_RS25635	PF09424	Yqey-like protein
SPH21_RS25640	PF00106	short chain dehydrogenase
SPH21_RS25650	PF01209	ubiE/COQ5 methyltransferase family
SPH21_RS25655	PF01926	50S ribosome-binding GTPase
SPH21_RS25660	PF01040	UbiA prenyltransferase family
SPH21_RS25675	PF03641	Possible lysine decarboxylase
SPH21_RS25695	PF00587	tRNA synthetase class II core domain (G, H, P, S and T)
SPH21_RS25695	PF02403	Seryl-tRNA synthetase N-terminal domain
SPH21_RS25700	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
SPH21_RS25710	PF00795	Carbon-nitrogen hydrolase
SPH21_RS25720	PF02540	NAD synthase
SPH21_RS25720	PF00795	Carbon-nitrogen hydrolase
SPH21_RS25740	PF03767	HAD superfamily, subfamily IIIB (Acid phosphatase)
SPH21_RS25750	PF00231	ATP synthase
SPH21_RS25755	PF00306	ATP synthase alpha/beta chain, C terminal domain
SPH21_RS25755	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain
SPH21_RS25755	PF02874	ATP synthase alpha/beta family, beta-barrel domain
SPH21_RS25760	PF00213	ATP synthase delta (OSCP) subunit
SPH21_RS25765	PF00430	ATP synthase B/B' CF(0)
SPH21_RS25770	PF00137	ATP synthase subunit C
SPH21_RS25775	PF00119	ATP synthase A chain
SPH21_RS25795	PF00912	Transglycosylase
SPH21_RS25795	PF00905	Penicillin binding protein transpeptidase domain
SPH21_RS25800	PF01541	GIY-YIG catalytic domain
SPH21_RS25800	PF08459	UvrC Helix-hairpin-helix N-terminal
SPH21_RS25810	PF03781	Sulfatase-modifying factor enzyme 1
SPH21_RS25825	PF00171	Aldehyde dehydrogenase family
SPH21_RS25835	PF00561	alpha/beta hydrolase fold
SPH21_RS25840	PF05343	M42 glutamyl aminopeptidase
SPH21_RS25845	PF07690	Major Facilitator Superfamily
SPH21_RS25855	PF00809	Pterin binding enzyme
SPH21_RS25875	PF01202	Shikimate kinase
SPH21_RS25885	PF13175	AAA ATPase domain
SPH21_RS25895	PF00885	6,7-dimethyl-8-ribityllumazine synthase
SPH21_RS25915	PF16881	N-terminal domain of lipoyl synthase of Radical_SAM family
SPH21_RS25915	PF04055	Radical SAM superfamily
SPH21_RS25920	PF01256	Carbohydrate kinase
SPH21_RS25920	PF03853	YjeF-related protein N-terminus
SPH21_RS25925	PF01717	Cobalamin-independent synthase, Catalytic domain
SPH21_RS25925	PF08267	Cobalamin-independent synthase, N-terminal domain
SPH21_RS25930	PF02080	TrkA-C domain
SPH21_RS25935	PF00999	Sodium/hydrogen exchanger family
SPH21_RS25940	PF02308	MgtC family
SPH21_RS25945	PF01883	Iron-sulfur cluster assembly protein
SPH21_RS25950	PF17755	UvrA DNA-binding domain
SPH21_RS25950	PF00005	ABC transporter
SPH21_RS25950	PF17760	UvrA interaction domain
SPH21_RS25960	PF00849	RNA pseudouridylate synthase
SPH21_RS25960	PF01479	S4 domain
SPH21_RS26000	PF00578	AhpC/TSA family
SPH21_RS26010	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26010	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS26010	PF18415	Histidine kinase receptor ArcB trans-membrane domain
SPH21_RS26010	PF00989	PAS fold
SPH21_RS26010	PF00072	Response regulator receiver domain
SPH21_RS26010	PF01627	Hpt domain
SPH21_RS26020	PF14322	Starch-binding associating with outer membrane
SPH21_RS26020	PF07980	SusD family
SPH21_RS26045	PF02743	Cache domain
SPH21_RS26045	PF00672	HAMP domain
SPH21_RS26045	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26045	PF06580	Histidine kinase
SPH21_RS26065	PF14028	Lantibiotic biosynthesis dehydratase C-term
SPH21_RS26065	PF04738	Lantibiotic dehydratase, N terminus
SPH21_RS26070	PF00578	AhpC/TSA family
SPH21_RS26075	PF00672	HAMP domain
SPH21_RS26075	PF02743	Cache domain
SPH21_RS26075	PF06580	Histidine kinase
SPH21_RS26075	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26080	PF10924	Protein of unknown function (DUF2711)
SPH21_RS26090	PF04616	Glycosyl hydrolases family 43
SPH21_RS26090	PF17851	Beta xylosidase C-terminal Concanavalin A-like domain 
SPH21_RS26110	PF04434	SWIM zinc finger
SPH21_RS26110	PF00176	SNF2 family N-terminal domain
SPH21_RS26110	PF00271	Helicase conserved C-terminal domain
SPH21_RS26115	PF05569	BlaR1 peptidase M56
SPH21_RS26115	PF00905	Penicillin binding protein transpeptidase domain
SPH21_RS26140	PF13742	OB-fold nucleic acid binding domain
SPH21_RS26140	PF02601	Exonuclease VII, large subunit
SPH21_RS26155	PF00535	Glycosyl transferase family 2
SPH21_RS26160	PF02397	Bacterial sugar transferase
SPH21_RS26165	PF00132	Bacterial transferase hexapeptide (six repeats)
SPH21_RS26170	PF00535	Glycosyl transferase family 2
SPH21_RS26175	PF13439	Glycosyltransferase Family 4
SPH21_RS26175	PF00534	Glycosyl transferases group 1
SPH21_RS26195	PF02397	Bacterial sugar transferase
SPH21_RS26210	PF13439	Glycosyltransferase Family 4
SPH21_RS26210	PF00534	Glycosyl transferases group 1
SPH21_RS26215	PF18698	Histidine kinase sensor domain
SPH21_RS26215	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26215	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS26215	PF00989	PAS fold
SPH21_RS26215	PF00672	HAMP domain
SPH21_RS26255	PF01223	DNA/RNA non-specific endonuclease
SPH21_RS26265	PF02416	mttA/Hcf106 family
SPH21_RS26305	PF01899	Na+/H+ ion antiporter subunit
SPH21_RS26345	PF00223	Photosystem I psaA/psaB protein
SPH21_RS26345	PF00691	OmpA family
SPH21_RS26365	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26365	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS26395	PF00072	Response regulator receiver domain
SPH21_RS26395	PF09456	RcsC Alpha-Beta-Loop (ABL)
SPH21_RS26395	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS26395	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26410	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26410	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS26420	PF00512	His Kinase A (phospho-acceptor) domain
SPH21_RS26420	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26420	PF00672	HAMP domain
SPH21_RS26425	PF06580	Histidine kinase
SPH21_RS26435	PF08534	Redoxin
SPH21_RS26440	PF12625	Arabinose-binding domain of AraC transcription regulator, N-term
SPH21_RS26440	PF12833	Helix-turn-helix domain
SPH21_RS26445	PF00672	HAMP domain
SPH21_RS26445	PF02743	Cache domain
SPH21_RS26445	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SPH21_RS26445	PF06580	Histidine kinase
SPH21_RS26450	PF17200	Single Cache domain 2
SPH21_RS26450	PF07730	Histidine kinase
