locus-tag class description SPYCW_RS00005 PF08299 Bacterial dnaA protein helix-turn-helix SPYCW_RS00005 PF00308 Bacterial dnaA protein SPYCW_RS00005 PF11638 DnaA N-terminal domain SPYCW_RS00015 PF00579 tRNA synthetases class I (W and Y) SPYCW_RS00020 PF03023 Lipid II flippase MurJ SPYCW_RS00025 PF02556 Preprotein translocase subunit SecB SPYCW_RS00035 PF06725 3D domain SPYCW_RS00035 PF03562 MltA specific insert domain SPYCW_RS00045 PF01546 Peptidase family M20/M25/M40 SPYCW_RS00045 PF07687 Peptidase dimerisation domain SPYCW_RS00055 PF01810 LysE type translocator SPYCW_RS00065 PF01926 50S ribosome-binding GTPase SPYCW_RS00070 PF14849 YidC periplasmic domain SPYCW_RS00070 PF02096 60Kd inner membrane protein SPYCW_RS00075 PF01809 Putative membrane protein insertion efficiency factor SPYCW_RS00080 PF00825 Ribonuclease P SPYCW_RS00085 PF00468 Ribosomal protein L34 SPYCW_RS00105 PF02798 Glutathione S-transferase, N-terminal domain SPYCW_RS00105 PF00043 Glutathione S-transferase, C-terminal domain SPYCW_RS00120 PF07237 Protein of unknown function (DUF1428) SPYCW_RS00125 PF00043 Glutathione S-transferase, C-terminal domain SPYCW_RS00125 PF13417 Glutathione S-transferase, N-terminal domain SPYCW_RS00130 PF00561 alpha/beta hydrolase fold SPYCW_RS00150 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS00155 PF13335 Magnesium chelatase, subunit ChlI C-terminal SPYCW_RS00155 PF01078 Magnesium chelatase, subunit ChlI SPYCW_RS00175 PF01464 Transglycosylase SLT domain SPYCW_RS00175 PF01551 Peptidase family M23 SPYCW_RS00175 PF10145 Phage-related minor tail protein SPYCW_RS00185 PF04107 Glutamate-cysteine ligase family 2(GCS2) SPYCW_RS00200 PF04452 RNA methyltransferase SPYCW_RS00220 PF01040 UbiA prenyltransferase family SPYCW_RS00235 PF02463 RecF/RecN/SMC N terminal domain SPYCW_RS00255 PF14815 NUDIX domain SPYCW_RS00255 PF00730 HhH-GPD superfamily base excision DNA repair protein SPYCW_RS00255 PF00633 Helix-hairpin-helix motif SPYCW_RS00260 PF00144 Beta-lactamase SPYCW_RS00265 PF09297 NADH pyrophosphatase zinc ribbon domain SPYCW_RS00265 PF00293 NUDIX domain SPYCW_RS00275 PF02321 Outer membrane efflux protein SPYCW_RS00290 PF06956 Regulator of RNA terminal phosphate cyclase SPYCW_RS00290 PF00158 Sigma-54 interaction domain SPYCW_RS00295 PF01139 tRNA-splicing ligase RtcB SPYCW_RS00305 PF01137 RNA 3'-terminal phosphate cyclase SPYCW_RS00305 PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain SPYCW_RS00335 PF00005 ABC transporter SPYCW_RS00335 PF02687 FtsX-like permease family SPYCW_RS00335 PF12704 MacB-like periplasmic core domain SPYCW_RS00345 PF02321 Outer membrane efflux protein SPYCW_RS00350 PF07969 Amidohydrolase family SPYCW_RS00355 PF03466 LysR substrate binding domain SPYCW_RS00355 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS00365 PF13378 Enolase C-terminal domain-like SPYCW_RS00365 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SPYCW_RS00370 PF00375 Sodium:dicarboxylate symporter family SPYCW_RS00375 PF07690 Major Facilitator Superfamily SPYCW_RS00385 PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family SPYCW_RS00390 PF01804 Penicillin amidase SPYCW_RS00410 PF05088 Bacterial NAD-glutamate dehydrogenase SPYCW_RS00440 PF00762 Ferrochelatase SPYCW_RS00445 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SPYCW_RS00445 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SPYCW_RS00455 PF13380 CoA binding domain SPYCW_RS00460 PF10609 NUBPL iron-transfer P-loop NTPase SPYCW_RS00465 PF12221 Bacterial membrane protein N terminal SPYCW_RS00465 PF01145 SPFH domain / Band 7 family SPYCW_RS00475 PF13180 PDZ domain SPYCW_RS00485 PF05872 Bacterial protein of unknown function (DUF853) SPYCW_RS00495 PF00067 Cytochrome P450 SPYCW_RS00510 PF14489 QueF-like protein SPYCW_RS00520 PF00581 Rhodanese-like domain SPYCW_RS00525 PF01053 Cys/Met metabolism PLP-dependent enzyme SPYCW_RS00530 PF12795 Mechanosensitive ion channel porin domain SPYCW_RS00530 PF12794 Mechanosensitive ion channel inner membrane domain 1 SPYCW_RS00530 PF00924 Mechanosensitive ion channel SPYCW_RS00535 PF00719 Inorganic pyrophosphatase SPYCW_RS00545 PF13393 Histidyl-tRNA synthetase SPYCW_RS00550 PF00472 RF-1 domain SPYCW_RS00550 PF03462 PCRF domain SPYCW_RS00555 PF17827 PrmC N-terminal domain SPYCW_RS00555 PF05175 Methyltransferase small domain SPYCW_RS00585 PF00571 CBS domain SPYCW_RS00595 PF00535 Glycosyl transferase family 2 SPYCW_RS00640 PF02463 RecF/RecN/SMC N terminal domain SPYCW_RS00650 PF03960 ArsC family SPYCW_RS00665 PF00005 ABC transporter SPYCW_RS00675 PF12848 ABC transporter SPYCW_RS00675 PF00005 ABC transporter SPYCW_RS00685 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPYCW_RS00705 PF01808 AICARFT/IMPCHase bienzyme SPYCW_RS00705 PF02142 MGS-like domain SPYCW_RS00710 PF02333 Phytase SPYCW_RS00715 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS00715 PF00593 TonB dependent receptor SPYCW_RS00725 PF00834 Ribulose-phosphate 3 epimerase family SPYCW_RS00745 PF00144 Beta-lactamase SPYCW_RS00765 PF01432 Peptidase family M3 SPYCW_RS00770 PF08450 SMP-30/Gluconolactonase/LRE-like region SPYCW_RS00775 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS00775 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS00775 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS00780 PF00108 Thiolase, N-terminal domain SPYCW_RS00780 PF02803 Thiolase, C-terminal domain SPYCW_RS00785 PF00106 short chain dehydrogenase SPYCW_RS00795 PF00625 Guanylate kinase SPYCW_RS00800 PF10755 Protein of unknown function (DUF2585) SPYCW_RS00805 PF00144 Beta-lactamase SPYCW_RS00815 PF10415 Fumarase C C-terminus SPYCW_RS00815 PF00206 Lyase SPYCW_RS00830 PF00475 Imidazoleglycerol-phosphate dehydratase SPYCW_RS00835 PF00117 Glutamine amidotransferase class-I SPYCW_RS00840 PF00977 Histidine biosynthesis protein SPYCW_RS00845 PF00977 Histidine biosynthesis protein SPYCW_RS00850 PF01699 Sodium/calcium exchanger protein SPYCW_RS00855 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SPYCW_RS00855 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SPYCW_RS00865 PF01925 Sulfite exporter TauE/SafE SPYCW_RS00870 PF03466 LysR substrate binding domain SPYCW_RS00870 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS00890 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS00890 PF00593 TonB dependent receptor SPYCW_RS00905 PF01636 Phosphotransferase enzyme family SPYCW_RS00920 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS00920 PF13977 BetI-type transcriptional repressor, C-terminal SPYCW_RS00925 PF00593 TonB dependent receptor SPYCW_RS00925 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS00930 PF01636 Phosphotransferase enzyme family SPYCW_RS00945 PF01979 Amidohydrolase family SPYCW_RS00965 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS00965 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS00965 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS00970 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS00970 PF00107 Zinc-binding dehydrogenase SPYCW_RS00975 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS00980 PF00067 Cytochrome P450 SPYCW_RS00985 PF03060 Nitronate monooxygenase SPYCW_RS00990 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS00990 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS00990 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS00995 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS00995 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS01000 PF00171 Aldehyde dehydrogenase family SPYCW_RS01010 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS01020 PF00106 short chain dehydrogenase SPYCW_RS01025 PF00501 AMP-binding enzyme SPYCW_RS01025 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS01030 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS01030 PF00107 Zinc-binding dehydrogenase SPYCW_RS01045 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS01045 PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SPYCW_RS01045 PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SPYCW_RS01050 PF00107 Zinc-binding dehydrogenase SPYCW_RS01050 PF16884 N-terminal domain of oxidoreductase SPYCW_RS01060 PF02803 Thiolase, C-terminal domain SPYCW_RS01060 PF00108 Thiolase, N-terminal domain SPYCW_RS01065 PF00171 Aldehyde dehydrogenase family SPYCW_RS01070 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS01070 PF13977 BetI-type transcriptional repressor, C-terminal SPYCW_RS01075 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS01075 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS01075 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS01080 PF02515 CoA-transferase family III SPYCW_RS01095 PF00795 Carbon-nitrogen hydrolase SPYCW_RS01095 PF02540 NAD synthase SPYCW_RS01100 PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region SPYCW_RS01100 PF00326 Prolyl oligopeptidase family SPYCW_RS01100 PF07676 WD40-like Beta Propeller Repeat SPYCW_RS01135 PF00175 Oxidoreductase NAD-binding domain SPYCW_RS01135 PF00042 Globin SPYCW_RS01135 PF00970 Oxidoreductase FAD-binding domain SPYCW_RS01150 PF00989 PAS fold SPYCW_RS01150 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS01150 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS01155 PF00196 Bacterial regulatory proteins, luxR family SPYCW_RS01155 PF00072 Response regulator receiver domain SPYCW_RS01160 PF00356 Bacterial regulatory proteins, lacI family SPYCW_RS01170 PF00593 TonB dependent receptor SPYCW_RS01170 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS01175 PF02435 Levansucrase/Invertase SPYCW_RS01180 PF00480 ROK family SPYCW_RS01190 PF07859 alpha/beta hydrolase fold SPYCW_RS01195 PF00501 AMP-binding enzyme SPYCW_RS01195 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS01215 PF02390 Putative methyltransferase SPYCW_RS01220 PF00438 S-adenosylmethionine synthetase, N-terminal domain SPYCW_RS01220 PF02772 S-adenosylmethionine synthetase, central domain SPYCW_RS01220 PF02773 S-adenosylmethionine synthetase, C-terminal domain SPYCW_RS01225 PF00795 Carbon-nitrogen hydrolase SPYCW_RS01245 PF01593 Flavin containing amine oxidoreductase SPYCW_RS01250 PF03641 Possible lysine decarboxylase SPYCW_RS01270 PF00501 AMP-binding enzyme SPYCW_RS01270 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS01275 PF00072 Response regulator receiver domain SPYCW_RS01275 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS01280 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS01280 PF00501 AMP-binding enzyme SPYCW_RS01285 PF01323 DSBA-like thioredoxin domain SPYCW_RS01290 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS01310 PF00849 RNA pseudouridylate synthase SPYCW_RS01310 PF01479 S4 domain SPYCW_RS01315 PF02537 CrcB-like protein, Camphor Resistance (CrcB) SPYCW_RS01335 PF00356 Bacterial regulatory proteins, lacI family SPYCW_RS01340 PF03632 Glycosyl hydrolase family 65 central catalytic domain SPYCW_RS01340 PF03633 Glycosyl hydrolase family 65, C-terminal domain SPYCW_RS01340 PF03636 Glycosyl hydrolase family 65, N-terminal domain SPYCW_RS01355 PF02685 Glucokinase SPYCW_RS01360 PF13382 Adenine deaminase C-terminal domain SPYCW_RS01360 PF01979 Amidohydrolase family SPYCW_RS01375 PF00330 Aconitase family (aconitate hydratase) SPYCW_RS01375 PF00694 Aconitase C-terminal domain SPYCW_RS01385 PF00196 Bacterial regulatory proteins, luxR family SPYCW_RS01385 PF00072 Response regulator receiver domain SPYCW_RS01400 PF07676 WD40-like Beta Propeller Repeat SPYCW_RS01400 PF00326 Prolyl oligopeptidase family SPYCW_RS01415 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS01420 PF00356 Bacterial regulatory proteins, lacI family SPYCW_RS01450 PF07536 HWE histidine kinase SPYCW_RS01450 PF13426 PAS domain SPYCW_RS01450 PF08447 PAS fold SPYCW_RS01460 PF02417 Chromate transporter SPYCW_RS01465 PF01544 CorA-like Mg2+ transporter protein SPYCW_RS01515 PF00962 Adenosine/AMP deaminase SPYCW_RS01520 PF00156 Phosphoribosyl transferase domain SPYCW_RS01545 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPYCW_RS01550 PF13525 Outer membrane lipoprotein SPYCW_RS01555 PF13476 AAA domain SPYCW_RS01555 PF02463 RecF/RecN/SMC N terminal domain SPYCW_RS01575 PF01653 NAD-dependent DNA ligase adenylation domain SPYCW_RS01575 PF00533 BRCA1 C Terminus (BRCT) domain SPYCW_RS01575 PF03119 NAD-dependent DNA ligase C4 zinc finger domain SPYCW_RS01575 PF03120 NAD-dependent DNA ligase OB-fold domain SPYCW_RS01610 PF00351 Biopterin-dependent aromatic amino acid hydroxylase SPYCW_RS01625 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPYCW_RS01625 PF00672 HAMP domain SPYCW_RS01625 PF17200 Single Cache domain 2 SPYCW_RS01630 PF01037 Lrp/AsnC ligand binding domain SPYCW_RS01635 PF05222 Alanine dehydrogenase/PNT, N-terminal domain SPYCW_RS01635 PF01262 Alanine dehydrogenase/PNT, C-terminal domain SPYCW_RS01660 PF00890 FAD binding domain SPYCW_RS01660 PF02910 Fumarate reductase flavoprotein C-term SPYCW_RS01680 PF02594 Uncharacterised ACR, YggU family COG1872 SPYCW_RS01685 PF14765 Polyketide synthase dehydratase SPYCW_RS01685 PF00698 Acyl transferase domain SPYCW_RS01685 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS01685 PF16197 Ketoacyl-synthetase C-terminal extension SPYCW_RS01685 PF00550 Phosphopantetheine attachment site SPYCW_RS01685 PF00109 Beta-ketoacyl synthase, N-terminal domain SPYCW_RS01685 PF02801 Beta-ketoacyl synthase, C-terminal domain SPYCW_RS01685 PF08659 KR domain SPYCW_RS01690 PF00694 Aconitase C-terminal domain SPYCW_RS01695 PF00753 Metallo-beta-lactamase superfamily SPYCW_RS01700 PF00330 Aconitase family (aconitate hydratase) SPYCW_RS01705 PF04116 Fatty acid hydroxylase superfamily SPYCW_RS01715 PF16363 GDP-mannose 4,6 dehydratase SPYCW_RS01740 PF01144 Coenzyme A transferase SPYCW_RS01755 PF01144 Coenzyme A transferase SPYCW_RS01760 PF03466 LysR substrate binding domain SPYCW_RS01760 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS01765 PF13419 Haloacid dehalogenase-like hydrolase SPYCW_RS01810 PF00171 Aldehyde dehydrogenase family SPYCW_RS01835 PF00293 NUDIX domain SPYCW_RS01840 PF01743 Poly A polymerase head domain SPYCW_RS01840 PF12626 Polymerase A arginine-rich C-terminus SPYCW_RS01840 PF12627 Probable RNA and SrmB- binding site of polymerase A SPYCW_RS01845 PF03707 Bacterial signalling protein N terminal repeat SPYCW_RS01845 PF00563 EAL domain SPYCW_RS01845 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS01850 PF03989 DNA gyrase C-terminal domain, beta-propeller SPYCW_RS01850 PF00521 DNA gyrase/topoisomerase IV, subunit A SPYCW_RS01860 PF09386 Antitoxin ParD SPYCW_RS01865 PF07687 Peptidase dimerisation domain SPYCW_RS01865 PF01546 Peptidase family M20/M25/M40 SPYCW_RS01910 PF00849 RNA pseudouridylate synthase SPYCW_RS01915 PF02525 Flavodoxin-like fold SPYCW_RS01920 PF02678 Pirin SPYCW_RS01920 PF17954 Quercetinase C-terminal cupin domain SPYCW_RS01925 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS01925 PF03466 LysR substrate binding domain SPYCW_RS01930 PF00072 Response regulator receiver domain SPYCW_RS01930 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS01940 PF04389 Peptidase family M28 SPYCW_RS01940 PF02225 PA domain SPYCW_RS01960 PF13185 GAF domain SPYCW_RS01965 PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain SPYCW_RS01965 PF00326 Prolyl oligopeptidase family SPYCW_RS01975 PF01196 Ribosomal protein L17 SPYCW_RS01980 PF01000 RNA polymerase Rpb3/RpoA insert domain SPYCW_RS01980 PF03118 Bacterial RNA polymerase, alpha chain C terminal domain SPYCW_RS01980 PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain SPYCW_RS01985 PF00411 Ribosomal protein S11 SPYCW_RS01990 PF00416 Ribosomal protein S13/S18 SPYCW_RS02005 PF00459 Inositol monophosphatase family SPYCW_RS02010 PF01523 Putative modulator of DNA gyrase SPYCW_RS02020 PF00326 Prolyl oligopeptidase family SPYCW_RS02030 PF03232 Ubiquinone biosynthesis protein COQ7 SPYCW_RS02040 PF13180 PDZ domain SPYCW_RS02040 PF03572 Peptidase family S41 SPYCW_RS02050 PF02590 Predicted SPOUT methyltransferase SPYCW_RS02060 PF01467 Cytidylyltransferase-like SPYCW_RS02070 PF01402 Ribbon-helix-helix protein, copG family SPYCW_RS02080 PF00171 Aldehyde dehydrogenase family SPYCW_RS02090 PF09423 PhoD-like phosphatase SPYCW_RS02090 PF16655 PhoD-like phosphatase, N-terminal domain SPYCW_RS02095 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS02100 PF01259 SAICAR synthetase SPYCW_RS02105 PF00305 Lipoxygenase SPYCW_RS02110 PF03707 Bacterial signalling protein N terminal repeat SPYCW_RS02110 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS02110 PF00563 EAL domain SPYCW_RS02125 PF00675 Insulinase (Peptidase family M16) SPYCW_RS02125 PF05193 Peptidase M16 inactive domain SPYCW_RS02130 PF09278 MerR, DNA binding SPYCW_RS02130 PF00376 MerR family regulatory protein SPYCW_RS02160 PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase SPYCW_RS02170 PF00210 Ferritin-like domain SPYCW_RS02195 PF02803 Thiolase, C-terminal domain SPYCW_RS02195 PF00108 Thiolase, N-terminal domain SPYCW_RS02200 PF01575 MaoC like domain SPYCW_RS02220 PF00534 Glycosyl transferases group 1 SPYCW_RS02240 PF01381 Helix-turn-helix SPYCW_RS02240 PF00717 Peptidase S24-like SPYCW_RS02250 PF00672 HAMP domain SPYCW_RS02250 PF12729 Four helix bundle sensory module for signal transduction SPYCW_RS02250 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPYCW_RS02255 PF00230 Major intrinsic protein SPYCW_RS02260 PF00483 Nucleotidyl transferase SPYCW_RS02265 PF00691 OmpA family SPYCW_RS02270 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS02270 PF17152 Periplasmic sensor domain SPYCW_RS02275 PF13689 YfiR/HmsC-like SPYCW_RS02280 PF01625 Peptide methionine sulfoxide reductase SPYCW_RS02290 PF02628 Cytochrome oxidase assembly protein SPYCW_RS02300 PF00572 Ribosomal protein L13 SPYCW_RS02305 PF00380 Ribosomal protein S9/S16 SPYCW_RS02335 PF00149 Calcineurin-like phosphoesterase SPYCW_RS02335 PF12320 Type 5 capsule protein repressor C-terminal domain SPYCW_RS02345 PF07859 alpha/beta hydrolase fold SPYCW_RS02355 PF00483 Nucleotidyl transferase SPYCW_RS02385 PF13085 2Fe-2S iron-sulfur cluster binding domain SPYCW_RS02395 PF03969 AFG1-like ATPase SPYCW_RS02405 PF00056 lactate/malate dehydrogenase, NAD binding domain SPYCW_RS02405 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain SPYCW_RS02415 PF00549 CoA-ligase SPYCW_RS02415 PF02629 CoA binding domain SPYCW_RS02420 PF00676 Dehydrogenase E1 component SPYCW_RS02420 PF02779 Transketolase, pyrimidine binding domain SPYCW_RS02420 PF16870 2-oxoglutarate dehydrogenase C-terminal SPYCW_RS02420 PF16078 2-oxoglutarate dehydrogenase N-terminus SPYCW_RS02425 PF02817 e3 binding domain SPYCW_RS02425 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SPYCW_RS02425 PF00364 Biotin-requiring enzyme SPYCW_RS02430 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPYCW_RS02430 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS02435 PF01546 Peptidase family M20/M25/M40 SPYCW_RS02435 PF07687 Peptidase dimerisation domain SPYCW_RS02440 PF03458 UPF0126 domain SPYCW_RS02445 PF00561 alpha/beta hydrolase fold SPYCW_RS02455 PF01343 Peptidase family S49 SPYCW_RS02465 PF00696 Amino acid kinase family SPYCW_RS02465 PF01472 PUA domain SPYCW_RS02475 PF01926 50S ribosome-binding GTPase SPYCW_RS02475 PF01018 GTP1/OBG SPYCW_RS02500 PF13302 Acetyltransferase (GNAT) domain SPYCW_RS02505 PF01957 NfeD-like C-terminal, partner-binding SPYCW_RS02510 PF16200 C-terminal region of band_7 SPYCW_RS02510 PF01145 SPFH domain / Band 7 family SPYCW_RS02515 PF03328 HpcH/HpaI aldolase/citrate lyase family SPYCW_RS02525 PF01474 Class-II DAHP synthetase family SPYCW_RS02535 PF03960 ArsC family SPYCW_RS02540 PF03009 Glycerophosphoryl diester phosphodiesterase family SPYCW_RS02545 PF01381 Helix-turn-helix SPYCW_RS02555 PF02548 Ketopantoate hydroxymethyltransferase SPYCW_RS02570 PF01926 50S ribosome-binding GTPase SPYCW_RS02570 PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SPYCW_RS02585 PF04235 Protein of unknown function (DUF418) SPYCW_RS02605 PF02769 AIR synthase related protein, C-terminal domain SPYCW_RS02605 PF18072 Formylglycinamide ribonucleotide amidotransferase linker domain SPYCW_RS02605 PF00586 AIR synthase related protein, N-terminal domain SPYCW_RS02620 PF02609 Exonuclease VII small subunit SPYCW_RS02625 PF00348 Polyprenyl synthetase SPYCW_RS02630 PF01467 Cytidylyltransferase-like SPYCW_RS02635 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPYCW_RS02640 PF02547 Queuosine biosynthesis protein SPYCW_RS02680 PF00563 EAL domain SPYCW_RS02680 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS02680 PF08447 PAS fold SPYCW_RS02680 PF08448 PAS fold SPYCW_RS02690 PF01702 Queuine tRNA-ribosyltransferase SPYCW_RS02695 PF00072 Response regulator receiver domain SPYCW_RS02700 PF03710 Glutamate-ammonia ligase adenylyltransferase SPYCW_RS02700 PF08335 GlnD PII-uridylyltransferase SPYCW_RS02705 PF00578 AhpC/TSA family SPYCW_RS02710 PF04305 Protein of unknown function (DUF455) SPYCW_RS02715 PF01551 Peptidase family M23 SPYCW_RS02720 PF01521 Iron-sulphur cluster biosynthesis SPYCW_RS02765 PF00072 Response regulator receiver domain SPYCW_RS02765 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS02765 PF13188 PAS domain SPYCW_RS02765 PF08448 PAS fold SPYCW_RS02765 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS02770 PF00155 Aminotransferase class I and II SPYCW_RS02785 PF01554 MatE SPYCW_RS02795 PF00166 Chaperonin 10 Kd subunit SPYCW_RS02800 PF00118 TCP-1/cpn60 chaperonin family SPYCW_RS02810 PF01965 DJ-1/PfpI family SPYCW_RS02835 PF01022 Bacterial regulatory protein, arsR family SPYCW_RS02840 PF02219 Methylenetetrahydrofolate reductase SPYCW_RS02845 PF02310 B12 binding domain SPYCW_RS02845 PF02607 B12 binding domain SPYCW_RS02845 PF02965 Vitamin B12 dependent methionine synthase, activation domain SPYCW_RS02845 PF02574 Homocysteine S-methyltransferase SPYCW_RS02845 PF00809 Pterin binding enzyme SPYCW_RS02850 PF02607 B12 binding domain SPYCW_RS02850 PF02574 Homocysteine S-methyltransferase SPYCW_RS02850 PF02310 B12 binding domain SPYCW_RS02850 PF00809 Pterin binding enzyme SPYCW_RS02850 PF02965 Vitamin B12 dependent methionine synthase, activation domain SPYCW_RS02875 PF01479 S4 domain SPYCW_RS02875 PF01728 FtsJ-like methyltransferase SPYCW_RS02885 PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase SPYCW_RS02890 PF14748 Pyrroline-5-carboxylate reductase dimerisation SPYCW_RS02890 PF03807 NADP oxidoreductase coenzyme F420-dependent SPYCW_RS02895 PF12802 MarR family SPYCW_RS02900 PF01063 Amino-transferase class IV SPYCW_RS02910 PF00999 Sodium/hydrogen exchanger family SPYCW_RS02920 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS02925 PF00884 Sulfatase SPYCW_RS02930 PF03781 Sulfatase-modifying factor enzyme 1 SPYCW_RS02945 PF16385 Domain of unknown function SPYCW_RS02945 PF00884 Sulfatase SPYCW_RS02970 PF03958 Bacterial type II/III secretion system short domain SPYCW_RS02970 PF00263 Bacterial type II and III secretion system protein SPYCW_RS02975 PF00437 Type II/IV secretion system protein SPYCW_RS02980 PF00482 Type II secretion system (T2SS), protein F SPYCW_RS02985 PF08334 Type II secretion system (T2SS), protein G SPYCW_RS02985 PF07963 Prokaryotic N-terminal methylation motif SPYCW_RS02990 PF12019 Type II transport protein GspH SPYCW_RS02990 PF07963 Prokaryotic N-terminal methylation motif SPYCW_RS02995 PF07963 Prokaryotic N-terminal methylation motif SPYCW_RS02995 PF02501 Type II secretion system (T2SS), protein I SPYCW_RS03000 PF07963 Prokaryotic N-terminal methylation motif SPYCW_RS03000 PF11612 Type II secretion system (T2SS), protein J SPYCW_RS03005 PF03934 Type II secretion system (T2SS), protein K SPYCW_RS03025 PF06750 Bacterial Peptidase A24 N-terminal domain SPYCW_RS03025 PF01478 Type IV leader peptidase family SPYCW_RS03030 PF00691 OmpA family SPYCW_RS03035 PF07676 WD40-like Beta Propeller Repeat SPYCW_RS03035 PF04052 TolB amino-terminal domain SPYCW_RS03045 PF02472 Biopolymer transport protein ExbD/TolR SPYCW_RS03050 PF01618 MotA/TolQ/ExbB proton channel family SPYCW_RS03055 PF03061 Thioesterase superfamily SPYCW_RS03060 PF05496 Holliday junction DNA helicase RuvB P-loop domain SPYCW_RS03060 PF05491 RuvB C-terminal winged helix domain SPYCW_RS03060 PF17864 RuvB AAA lid domain SPYCW_RS03075 PF01330 RuvA N terminal domain SPYCW_RS03075 PF07499 RuvA, C-terminal domain SPYCW_RS03080 PF02075 Crossover junction endodeoxyribonuclease RuvC SPYCW_RS03085 PF01709 Transcriptional regulator SPYCW_RS03090 PF01906 Putative heavy-metal-binding SPYCW_RS03095 PF10073 Uncharacterized protein conserved in bacteria (DUF2312) SPYCW_RS03100 PF01979 Amidohydrolase family SPYCW_RS03110 PF00224 Pyruvate kinase, barrel domain SPYCW_RS03110 PF02887 Pyruvate kinase, alpha/beta domain SPYCW_RS03115 PF04376 Arginine-tRNA-protein transferase, N terminus SPYCW_RS03115 PF04377 Arginine-tRNA-protein transferase, C terminus SPYCW_RS03130 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS03145 PF00149 Calcineurin-like phosphoesterase SPYCW_RS03150 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPYCW_RS03160 PF01406 tRNA synthetases class I (C) catalytic domain SPYCW_RS03180 PF00211 Adenylate and Guanylate cyclase catalytic domain SPYCW_RS03195 PF01722 BolA-like protein SPYCW_RS03200 PF00462 Glutaredoxin SPYCW_RS03205 PF03965 Penicillinase repressor SPYCW_RS03215 PF16123 Hydroxyacylglutathione hydrolase C-terminus SPYCW_RS03215 PF00753 Metallo-beta-lactamase superfamily SPYCW_RS03235 PF02445 Quinolinate synthetase A protein SPYCW_RS03255 PF00873 AcrB/AcrD/AcrF family SPYCW_RS03260 PF04286 Protein of unknown function (DUF445) SPYCW_RS03270 PF17432 Domain of unknown function (DUF3458_C) ARM repeats SPYCW_RS03270 PF11940 Domain of unknown function (DUF3458) Ig-like fold SPYCW_RS03270 PF01433 Peptidase family M1 domain SPYCW_RS03285 PF00005 ABC transporter SPYCW_RS03290 PF02405 Permease MlaE SPYCW_RS03300 PF01053 Cys/Met metabolism PLP-dependent enzyme SPYCW_RS03305 PF00939 Sodium:sulfate symporter transmembrane region SPYCW_RS03310 PF02578 Multi-copper polyphenol oxidoreductase laccase SPYCW_RS03325 PF01790 Prolipoprotein diacylglyceryl transferase SPYCW_RS03330 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS03330 PF00501 AMP-binding enzyme SPYCW_RS03335 PF01292 Prokaryotic cytochrome b561 SPYCW_RS03340 PF00174 Oxidoreductase molybdopterin binding domain SPYCW_RS03350 PF13280 WYL domain SPYCW_RS03350 PF08279 HTH domain SPYCW_RS03360 PF10459 Peptidase S46 SPYCW_RS03365 PF00764 Arginosuccinate synthase SPYCW_RS03370 PF01212 Beta-eliminating lyase SPYCW_RS03385 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPYCW_RS03395 PF01323 DSBA-like thioredoxin domain SPYCW_RS03405 PF01638 HxlR-like helix-turn-helix SPYCW_RS03415 PF02617 ATP-dependent Clp protease adaptor protein ClpS SPYCW_RS03425 PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus SPYCW_RS03425 PF00561 alpha/beta hydrolase fold SPYCW_RS03430 PF00155 Aminotransferase class I and II SPYCW_RS03440 PF01425 Amidase SPYCW_RS03445 PF07690 Major Facilitator Superfamily SPYCW_RS03455 PF12697 Alpha/beta hydrolase family SPYCW_RS03460 PF01037 Lrp/AsnC ligand binding domain SPYCW_RS03465 PF01053 Cys/Met metabolism PLP-dependent enzyme SPYCW_RS03470 PF00709 Adenylosuccinate synthetase SPYCW_RS03485 PF13393 Histidyl-tRNA synthetase SPYCW_RS03490 PF01842 ACT domain SPYCW_RS03490 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPYCW_RS03490 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SPYCW_RS03495 PF00266 Aminotransferase class-V SPYCW_RS03505 PF03641 Possible lysine decarboxylase SPYCW_RS03510 PF00034 Cytochrome c SPYCW_RS03515 PF00034 Cytochrome c SPYCW_RS03520 PF01817 Chorismate mutase type II SPYCW_RS03520 PF00800 Prephenate dehydratase SPYCW_RS03540 PF01367 5'-3' exonuclease, C-terminal SAM fold SPYCW_RS03540 PF02739 5'-3' exonuclease, N-terminal resolvase-like domain SPYCW_RS03540 PF00476 DNA polymerase family A SPYCW_RS03540 PF01612 3'-5' exonuclease SPYCW_RS03545 PF00135 Carboxylesterase family SPYCW_RS03550 PF00583 Acetyltransferase (GNAT) family SPYCW_RS03560 PF02222 ATP-grasp domain SPYCW_RS03570 PF02798 Glutathione S-transferase, N-terminal domain SPYCW_RS03570 PF00043 Glutathione S-transferase, C-terminal domain SPYCW_RS03575 PF01638 HxlR-like helix-turn-helix SPYCW_RS03590 PF13361 UvrD-like helicase C-terminal domain SPYCW_RS03590 PF00580 UvrD/REP helicase N-terminal domain SPYCW_RS03610 PF08401 Domain of unknown function (DUF1738) SPYCW_RS03610 PF18818 Metallopeptidase superfamily domain SPYCW_RS03610 PF13362 Toprim domain SPYCW_RS03705 PF01464 Transglycosylase SLT domain SPYCW_RS03725 PF02627 Carboxymuconolactone decarboxylase family SPYCW_RS03730 PF01593 Flavin containing amine oxidoreductase SPYCW_RS03735 PF00107 Zinc-binding dehydrogenase SPYCW_RS03735 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS03745 PF03466 LysR substrate binding domain SPYCW_RS03745 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS03750 PF02534 Type IV secretory system Conjugative DNA transfer SPYCW_RS03760 PF00437 Type II/IV secretion system protein SPYCW_RS03775 PF03135 CagE, TrbE, VirB family, component of type IV transporter system SPYCW_RS03790 PF04610 TrbL/VirB6 plasmid conjugal transfer protein SPYCW_RS03795 PF04335 VirB8 protein SPYCW_RS03805 PF03743 Bacterial conjugation TrbI-like protein SPYCW_RS03825 PF00117 Glutamine amidotransferase class-I SPYCW_RS03825 PF02540 NAD synthase SPYCW_RS03825 PF00958 GMP synthase C terminal domain SPYCW_RS03835 PF00534 Glycosyl transferases group 1 SPYCW_RS03835 PF13439 Glycosyltransferase Family 4 SPYCW_RS03845 PF00171 Aldehyde dehydrogenase family SPYCW_RS03850 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPYCW_RS03850 PF00205 Thiamine pyrophosphate enzyme, central domain SPYCW_RS03850 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPYCW_RS03855 PF06213 Cobalamin biosynthesis protein CobT SPYCW_RS03855 PF11775 Cobalamin biosynthesis protein CobT VWA domain SPYCW_RS03860 PF04480 Protein of unknown function (DUF559) SPYCW_RS03865 PF07690 Major Facilitator Superfamily SPYCW_RS03875 PF12556 Cobaltochelatase CobS subunit N terminal SPYCW_RS03875 PF08406 CbbQ/NirQ/NorQ C-terminal SPYCW_RS03875 PF07728 AAA domain (dynein-related subfamily) SPYCW_RS03885 PF00226 DnaJ domain SPYCW_RS03895 PF04209 homogentisate 1,2-dioxygenase SPYCW_RS03905 PF02678 Pirin SPYCW_RS03905 PF05726 Pirin C-terminal cupin domain SPYCW_RS03910 PF00561 alpha/beta hydrolase fold SPYCW_RS03915 PF01965 DJ-1/PfpI family SPYCW_RS03915 PF12833 Helix-turn-helix domain SPYCW_RS03935 PF02567 Phenazine biosynthesis-like protein SPYCW_RS03940 PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region SPYCW_RS03940 PF01243 Pyridoxamine 5'-phosphate oxidase SPYCW_RS03945 PF00226 DnaJ domain SPYCW_RS03945 PF00684 DnaJ central domain SPYCW_RS03945 PF01556 DnaJ C terminal domain SPYCW_RS03950 PF03631 Virulence factor BrkB SPYCW_RS03965 PF01264 Chorismate synthase SPYCW_RS03970 PF03600 Citrate transporter SPYCW_RS03970 PF02080 TrkA-C domain SPYCW_RS03975 PF00375 Sodium:dicarboxylate symporter family SPYCW_RS03980 PF00375 Sodium:dicarboxylate symporter family SPYCW_RS03990 PF00067 Cytochrome P450 SPYCW_RS04000 PF01521 Iron-sulphur cluster biosynthesis SPYCW_RS04005 PF01883 Iron-sulfur cluster assembly protein SPYCW_RS04010 PF00266 Aminotransferase class-V SPYCW_RS04015 PF01458 Uncharacterized protein family (UPF0051) SPYCW_RS04020 PF00005 ABC transporter SPYCW_RS04035 PF01458 Uncharacterized protein family (UPF0051) SPYCW_RS04055 PF01180 Dihydroorotate dehydrogenase SPYCW_RS04065 PF00501 AMP-binding enzyme SPYCW_RS04075 PF00753 Metallo-beta-lactamase superfamily SPYCW_RS04075 PF16123 Hydroxyacylglutathione hydrolase C-terminus SPYCW_RS04120 PF03129 Anticodon binding domain SPYCW_RS04120 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPYCW_RS04120 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPYCW_RS04120 PF02824 TGS domain SPYCW_RS04150 PF00005 ABC transporter SPYCW_RS04160 PF02694 Uncharacterised BCR, YnfA/UPF0060 family SPYCW_RS04175 PF04055 Radical SAM superfamily SPYCW_RS04190 PF03466 LysR substrate binding domain SPYCW_RS04190 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS04200 PF02768 DNA polymerase III beta subunit, C-terminal domain SPYCW_RS04200 PF00712 DNA polymerase III beta subunit, N-terminal domain SPYCW_RS04200 PF02767 DNA polymerase III beta subunit, central domain SPYCW_RS04205 PF07995 Glucose / Sorbosone dehydrogenase SPYCW_RS04215 PF01118 Semialdehyde dehydrogenase, NAD binding domain SPYCW_RS04220 PF00877 NlpC/P60 family SPYCW_RS04225 PF00883 Cytosol aminopeptidase family, catalytic domain SPYCW_RS04225 PF02789 Cytosol aminopeptidase family, N-terminal domain SPYCW_RS04235 PF00743 Flavin-binding monooxygenase-like SPYCW_RS04240 PF01865 Protein of unknown function DUF47 SPYCW_RS04245 PF01384 Phosphate transporter family SPYCW_RS04255 PF00919 Uncharacterized protein family UPF0004 SPYCW_RS04255 PF18693 TRAM domain SPYCW_RS04255 PF04055 Radical SAM superfamily SPYCW_RS04260 PF17392 Urocanase C-terminal domain SPYCW_RS04260 PF17391 Urocanase N-terminal domain SPYCW_RS04260 PF01175 Urocanase Rossmann-like domain SPYCW_RS04270 PF00221 Aromatic amino acid lyase SPYCW_RS04275 PF01979 Amidohydrolase family SPYCW_RS04335 PF00905 Penicillin binding protein transpeptidase domain SPYCW_RS04335 PF00912 Transglycosylase SPYCW_RS04340 PF08713 DNA alkylation repair enzyme SPYCW_RS04345 PF02321 Outer membrane efflux protein SPYCW_RS04350 PF00873 AcrB/AcrD/AcrF family SPYCW_RS04355 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPYCW_RS04360 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS04360 PF08361 MAATS-type transcriptional repressor, C-terminal region SPYCW_RS04370 PF00584 SecE/Sec61-gamma subunits of protein translocation complex SPYCW_RS04375 PF02357 Transcription termination factor nusG SPYCW_RS04375 PF00467 KOW motif SPYCW_RS04385 PF00298 Ribosomal protein L11, RNA binding domain SPYCW_RS04385 PF03946 Ribosomal protein L11, N-terminal domain SPYCW_RS04390 PF00687 Ribosomal protein L1p/L10e family SPYCW_RS04395 PF03379 CcmB protein SPYCW_RS04400 PF00005 ABC transporter SPYCW_RS04410 PF01329 Pterin 4 alpha carbinolamine dehydratase SPYCW_RS04420 PF13520 Amino acid permease SPYCW_RS04445 PF13443 Cro/C1-type HTH DNA-binding domain SPYCW_RS04465 PF00466 Ribosomal protein L10 SPYCW_RS04470 PF00542 Ribosomal protein L7/L12 C-terminal domain SPYCW_RS04470 PF16320 Ribosomal protein L7/L12 dimerisation domain SPYCW_RS04480 PF01820 D-ala D-ala ligase N-terminus SPYCW_RS04480 PF07478 D-ala D-ala ligase C-terminus SPYCW_RS04490 PF03055 Retinal pigment epithelial membrane protein SPYCW_RS04495 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS04500 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS04520 PF01272 Transcription elongation factor, GreA/GreB, C-term SPYCW_RS04520 PF03449 Transcription elongation factor, N-terminal SPYCW_RS04525 PF01464 Transglycosylase SLT domain SPYCW_RS04530 PF00701 Dihydrodipicolinate synthetase family SPYCW_RS04535 PF01668 SmpB protein SPYCW_RS04545 PF05649 Peptidase family M13 SPYCW_RS04545 PF01431 Peptidase family M13 SPYCW_RS04550 PF00072 Response regulator receiver domain SPYCW_RS04550 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS04550 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS04550 PF08448 PAS fold SPYCW_RS04550 PF13188 PAS domain SPYCW_RS04560 PF00154 recA bacterial DNA recombination protein SPYCW_RS04570 PF00491 Arginase family SPYCW_RS04590 PF02272 DHHA1 domain SPYCW_RS04590 PF01411 tRNA synthetases class II (A) SPYCW_RS04590 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPYCW_RS04610 PF08990 Erythronolide synthase docking SPYCW_RS04610 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS04610 PF08659 KR domain SPYCW_RS04610 PF16197 Ketoacyl-synthetase C-terminal extension SPYCW_RS04610 PF00550 Phosphopantetheine attachment site SPYCW_RS04610 PF02801 Beta-ketoacyl synthase, C-terminal domain SPYCW_RS04610 PF00698 Acyl transferase domain SPYCW_RS04610 PF00109 Beta-ketoacyl synthase, N-terminal domain SPYCW_RS04610 PF14765 Polyketide synthase dehydratase SPYCW_RS04625 PF02699 Preprotein translocase subunit SPYCW_RS04630 PF02355 Protein export membrane protein SPYCW_RS04635 PF02355 Protein export membrane protein SPYCW_RS04635 PF07549 SecD/SecF GG Motif SPYCW_RS04640 PF13439 Glycosyltransferase Family 4 SPYCW_RS04640 PF00534 Glycosyl transferases group 1 SPYCW_RS04655 PF00005 ABC transporter SPYCW_RS04655 PF16326 ABC transporter C-terminal domain SPYCW_RS04675 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SPYCW_RS04675 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPYCW_RS04680 PF04304 Protein of unknown function (DUF454) SPYCW_RS04685 PF00593 TonB dependent receptor SPYCW_RS04685 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS04690 PF01578 Cytochrome C assembly protein SPYCW_RS04695 PF03100 CcmE SPYCW_RS04700 PF01578 Cytochrome C assembly protein SPYCW_RS04700 PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal SPYCW_RS04705 PF08534 Redoxin SPYCW_RS04710 PF03918 Cytochrome C biogenesis protein SPYCW_RS04720 PF02705 K+ potassium transporter SPYCW_RS04745 PF00106 short chain dehydrogenase SPYCW_RS04750 PF00561 alpha/beta hydrolase fold SPYCW_RS04760 PF03795 YCII-related domain SPYCW_RS04765 PF08281 Sigma-70, region 4 SPYCW_RS04765 PF04542 Sigma-70 region 2 SPYCW_RS04790 PF01176 Translation initiation factor 1A / IF-1 SPYCW_RS04795 PF00313 'Cold-shock' DNA-binding domain SPYCW_RS04805 PF00682 HMGL-like SPYCW_RS04805 PF08502 LeuA allosteric (dimerisation) domain SPYCW_RS04820 PF04264 YceI-like domain SPYCW_RS04835 PF00202 Aminotransferase class-III SPYCW_RS04845 PF00155 Aminotransferase class I and II SPYCW_RS04855 PF01450 Acetohydroxy acid isomeroreductase, catalytic domain SPYCW_RS04855 PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain SPYCW_RS04860 PF10369 Small subunit of acetolactate synthase SPYCW_RS04865 PF00205 Thiamine pyrophosphate enzyme, central domain SPYCW_RS04865 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPYCW_RS04865 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPYCW_RS04885 PF03466 LysR substrate binding domain SPYCW_RS04885 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS04890 PF00753 Metallo-beta-lactamase superfamily SPYCW_RS04900 PF13614 AAA domain SPYCW_RS04915 PF00912 Transglycosylase SPYCW_RS04920 PF08460 Bacterial SH3 domain SPYCW_RS04920 PF01551 Peptidase family M23 SPYCW_RS04930 PF00140 Sigma-70 factor, region 1.2 SPYCW_RS04930 PF04542 Sigma-70 region 2 SPYCW_RS04930 PF04545 Sigma-70, region 4 SPYCW_RS04935 PF00849 RNA pseudouridylate synthase SPYCW_RS04940 PF10090 Histidine phosphotransferase C-terminal domain SPYCW_RS04955 PF01584 CheW-like domain SPYCW_RS04955 PF02895 Signal transducing histidine kinase, homodimeric domain SPYCW_RS04955 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS04955 PF01627 Hpt domain SPYCW_RS04955 PF00072 Response regulator receiver domain SPYCW_RS04965 PF00072 Response regulator receiver domain SPYCW_RS04970 PF00072 Response regulator receiver domain SPYCW_RS04970 PF01339 CheB methylesterase SPYCW_RS04975 PF03705 CheR methyltransferase, all-alpha domain SPYCW_RS04975 PF01739 CheR methyltransferase, SAM binding domain SPYCW_RS04980 PF01510 N-acetylmuramoyl-L-alanine amidase SPYCW_RS04985 PF01979 Amidohydrolase family SPYCW_RS04990 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPYCW_RS04990 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPYCW_RS04995 PF03652 Holliday junction resolvase SPYCW_RS05005 PF13687 Domain of unknown function (DUF4153) SPYCW_RS05010 PF02686 Glu-tRNAGln amidotransferase C subunit SPYCW_RS05015 PF01425 Amidase SPYCW_RS05020 PF02637 GatB domain SPYCW_RS05020 PF02934 GatB/GatE catalytic domain SPYCW_RS05030 PF07969 Amidohydrolase family SPYCW_RS05045 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPYCW_RS05045 PF05698 Bacterial trigger factor protein (TF) C-terminus SPYCW_RS05045 PF05697 Bacterial trigger factor protein (TF) SPYCW_RS05055 PF00111 2Fe-2S iron-sulfur cluster binding domain SPYCW_RS05060 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPYCW_RS05060 PF00588 SpoU rRNA Methylase family SPYCW_RS05070 PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain SPYCW_RS05070 PF00326 Prolyl oligopeptidase family SPYCW_RS05080 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPYCW_RS05095 PF00005 ABC transporter SPYCW_RS05100 PF01061 ABC-2 type transporter SPYCW_RS05110 PF11954 Domain of unknown function (DUF3471) SPYCW_RS05110 PF00144 Beta-lactamase SPYCW_RS05115 PF00216 Bacterial DNA-binding protein SPYCW_RS05120 PF00575 S1 RNA binding domain SPYCW_RS05125 PF02224 Cytidylate kinase SPYCW_RS05135 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPYCW_RS05170 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS05180 PF02559 CarD-like/TRCF domain SPYCW_RS05185 PF01416 tRNA pseudouridine synthase SPYCW_RS05190 PF00551 Formyl transferase SPYCW_RS05190 PF02911 Formyl transferase, C-terminal domain SPYCW_RS05195 PF13662 Toprim domain SPYCW_RS05195 PF02132 RecR protein SPYCW_RS05200 PF01327 Polypeptide deformylase SPYCW_RS05205 PF01025 GrpE SPYCW_RS05210 PF01628 HrcA protein C terminal domain SPYCW_RS05220 PF03725 3' exoribonuclease family, domain 2 SPYCW_RS05220 PF01138 3' exoribonuclease family, domain 1 SPYCW_RS05225 PF01725 Ham1 family SPYCW_RS05230 PF04055 Radical SAM superfamily SPYCW_RS05230 PF06969 HemN C-terminal domain SPYCW_RS05235 PF02899 Phage integrase, N-terminal SAM-like domain SPYCW_RS05235 PF00589 Phage integrase family SPYCW_RS05240 PF09335 SNARE associated Golgi protein SPYCW_RS05245 PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain SPYCW_RS05245 PF02951 Prokaryotic glutathione synthetase, N-terminal domain SPYCW_RS05250 PF02021 Uncharacterised protein family UPF0102 SPYCW_RS05255 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SPYCW_RS05265 PF00707 Translation initiation factor IF-3, C-terminal domain SPYCW_RS05265 PF05198 Translation initiation factor IF-3, N-terminal domain SPYCW_RS05295 PF05973 Phage derived protein Gp49-like (DUF891) SPYCW_RS05300 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPYCW_RS05300 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPYCW_RS05305 PF04851 Type III restriction enzyme, res subunit SPYCW_RS05305 PF17757 UvrB interaction domain SPYCW_RS05305 PF00271 Helicase conserved C-terminal domain SPYCW_RS05305 PF12344 Ultra-violet resistance protein B SPYCW_RS05305 PF02151 UvrB/uvrC motif SPYCW_RS05325 PF00144 Beta-lactamase SPYCW_RS05330 PF00550 Phosphopantetheine attachment site SPYCW_RS05335 PF00109 Beta-ketoacyl synthase, N-terminal domain SPYCW_RS05335 PF02801 Beta-ketoacyl synthase, C-terminal domain SPYCW_RS05340 PF02618 YceG-like family SPYCW_RS05355 PF08534 Redoxin SPYCW_RS05370 PF12697 Alpha/beta hydrolase family SPYCW_RS05370 PF08241 Methyltransferase domain SPYCW_RS05385 PF01476 LysM domain SPYCW_RS05385 PF01551 Peptidase family M23 SPYCW_RS05390 PF01975 Survival protein SurE SPYCW_RS05395 PF02403 Seryl-tRNA synthetase N-terminal domain SPYCW_RS05395 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPYCW_RS05405 PF01258 Prokaryotic dksA/traR C4-type zinc finger SPYCW_RS05435 PF01634 ATP phosphoribosyltransferase SPYCW_RS05440 PF00815 Histidinol dehydrogenase SPYCW_RS05445 PF01029 NusB family SPYCW_RS05450 PF00586 AIR synthase related protein, N-terminal domain SPYCW_RS05450 PF02769 AIR synthase related protein, C-terminal domain SPYCW_RS05455 PF03030 Inorganic H+ pyrophosphatase SPYCW_RS05460 PF03144 Elongation factor Tu domain 2 SPYCW_RS05460 PF16658 Class II release factor RF3, C-terminal domain SPYCW_RS05460 PF00009 Elongation factor Tu GTP binding domain SPYCW_RS05465 PF11798 IMS family HHH motif SPYCW_RS05465 PF11799 impB/mucB/samB family C-terminal domain SPYCW_RS05465 PF00817 impB/mucB/samB family SPYCW_RS05475 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPYCW_RS05475 PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase SPYCW_RS05490 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS05490 PF00072 Response regulator receiver domain SPYCW_RS05495 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS05495 PF08521 Two-component sensor kinase N-terminal SPYCW_RS05495 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS05505 PF03435 Saccharopine dehydrogenase NADP binding domain SPYCW_RS05515 PF00692 dUTPase SPYCW_RS05520 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPYCW_RS05530 PF06793 Uncharacterised protein family (UPF0262) SPYCW_RS05535 PF00772 DnaB-like helicase N terminal domain SPYCW_RS05535 PF03796 DnaB-like helicase C terminal domain SPYCW_RS05540 PF01507 Phosphoadenosine phosphosulfate reductase family SPYCW_RS05550 PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain SPYCW_RS05550 PF01077 Nitrite and sulphite reductase 4Fe-4S domain SPYCW_RS05560 PF14824 Sirohaem biosynthesis protein central SPYCW_RS05560 PF10414 Sirohaem synthase dimerisation region SPYCW_RS05560 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SPYCW_RS05565 PF00171 Aldehyde dehydrogenase family SPYCW_RS05570 PF00561 alpha/beta hydrolase fold SPYCW_RS05575 PF00534 Glycosyl transferases group 1 SPYCW_RS05575 PF13439 Glycosyltransferase Family 4 SPYCW_RS05585 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPYCW_RS05585 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SPYCW_RS05600 PF00108 Thiolase, N-terminal domain SPYCW_RS05600 PF02803 Thiolase, C-terminal domain SPYCW_RS05605 PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ SPYCW_RS05610 PF00171 Aldehyde dehydrogenase family SPYCW_RS05615 PF01594 AI-2E family transporter SPYCW_RS05635 PF04542 Sigma-70 region 2 SPYCW_RS05635 PF08281 Sigma-70, region 4 SPYCW_RS05655 PF04371 Porphyromonas-type peptidyl-arginine deiminase SPYCW_RS05665 PF00326 Prolyl oligopeptidase family SPYCW_RS05670 PF00163 Ribosomal protein S4/S9 N-terminal domain SPYCW_RS05670 PF01479 S4 domain SPYCW_RS05690 PF00588 SpoU rRNA Methylase family SPYCW_RS05695 PF03477 ATP cone domain SPYCW_RS05705 PF00464 Serine hydroxymethyltransferase SPYCW_RS05710 PF02502 Ribose/Galactose Isomerase SPYCW_RS05715 PF02129 X-Pro dipeptidyl-peptidase (S15 family) SPYCW_RS05720 PF00266 Aminotransferase class-V SPYCW_RS05725 PF00111 2Fe-2S iron-sulfur cluster binding domain SPYCW_RS05735 PF12169 DNA polymerase III subunits gamma and tau domain III SPYCW_RS05735 PF12168 DNA polymerase III subunits tau domain IV DnaB-binding SPYCW_RS05735 PF12170 DNA polymerase III tau subunit V interacting with alpha SPYCW_RS05740 PF02575 YbaB/EbfC DNA-binding family SPYCW_RS05745 PF05362 Lon protease (S16) C-terminal proteolytic domain SPYCW_RS05745 PF02190 ATP-dependent protease La (LON) substrate-binding domain SPYCW_RS05745 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS05750 PF00216 Bacterial DNA-binding protein SPYCW_RS05765 PF00072 Response regulator receiver domain SPYCW_RS05765 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS05770 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS05780 PF00043 Glutathione S-transferase, C-terminal domain SPYCW_RS05780 PF02798 Glutathione S-transferase, N-terminal domain SPYCW_RS05785 PF02153 Prephenate dehydrogenase SPYCW_RS05785 PF01817 Chorismate mutase type II SPYCW_RS05790 PF00348 Polyprenyl synthetase SPYCW_RS05800 PF00270 DEAD/DEAH box helicase SPYCW_RS05800 PF04408 Helicase associated domain (HA2) SPYCW_RS05800 PF00271 Helicase conserved C-terminal domain SPYCW_RS05800 PF08482 ATP-dependent helicase C-terminal SPYCW_RS05835 PF00113 Enolase, C-terminal TIM barrel domain SPYCW_RS05835 PF03952 Enolase, N-terminal domain SPYCW_RS05845 PF00676 Dehydrogenase E1 component SPYCW_RS05850 PF02779 Transketolase, pyrimidine binding domain SPYCW_RS05850 PF02780 Transketolase, C-terminal domain SPYCW_RS05850 PF00364 Biotin-requiring enzyme SPYCW_RS05860 PF00132 Bacterial transferase hexapeptide (six repeats) SPYCW_RS05875 PF00106 short chain dehydrogenase SPYCW_RS05880 PF07396 Phosphate-selective porin O and P SPYCW_RS05890 PF00072 Response regulator receiver domain SPYCW_RS05890 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS05895 PF01895 PhoU domain SPYCW_RS05900 PF00005 ABC transporter SPYCW_RS05905 PF00528 Binding-protein-dependent transport system inner membrane component SPYCW_RS05910 PF00528 Binding-protein-dependent transport system inner membrane component SPYCW_RS05935 PF17760 UvrA interaction domain SPYCW_RS05935 PF17755 UvrA DNA-binding domain SPYCW_RS05940 PF01431 Peptidase family M13 SPYCW_RS05940 PF05649 Peptidase family M13 SPYCW_RS05945 PF02028 BCCT, betaine/carnitine/choline family transporter SPYCW_RS05965 PF04397 LytTr DNA-binding domain SPYCW_RS05965 PF00072 Response regulator receiver domain SPYCW_RS05970 PF07694 5TMR of 5TMR-LYT SPYCW_RS05970 PF06580 Histidine kinase SPYCW_RS05970 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS05975 PF10458 Valyl tRNA synthetase tRNA binding arm SPYCW_RS05975 PF08264 Anticodon-binding domain of tRNA SPYCW_RS05975 PF00133 tRNA synthetases class I (I, L, M and V) SPYCW_RS05980 PF07676 WD40-like Beta Propeller Repeat SPYCW_RS05980 PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region SPYCW_RS05980 PF00326 Prolyl oligopeptidase family SPYCW_RS05985 PF01979 Amidohydrolase family SPYCW_RS05990 PF04228 Putative neutral zinc metallopeptidase SPYCW_RS06010 PF01546 Peptidase family M20/M25/M40 SPYCW_RS06010 PF07687 Peptidase dimerisation domain SPYCW_RS06020 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS06030 PF03741 Integral membrane protein TerC family SPYCW_RS06035 PF00463 Isocitrate lyase family SPYCW_RS06040 PF06114 IrrE N-terminal-like domain SPYCW_RS06040 PF09856 Predicted transcriptional regulator (DUF2083) SPYCW_RS06040 PF01381 Helix-turn-helix SPYCW_RS06050 PF11871 Domain of unknown function (DUF3391) SPYCW_RS06050 PF01966 HD domain SPYCW_RS06055 PF01050 Mannose-6-phosphate isomerase SPYCW_RS06055 PF00483 Nucleotidyl transferase SPYCW_RS06060 PF02397 Bacterial sugar transferase SPYCW_RS06065 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS06065 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS06070 PF02954 Bacterial regulatory protein, Fis family SPYCW_RS06070 PF00072 Response regulator receiver domain SPYCW_RS06070 PF00158 Sigma-54 interaction domain SPYCW_RS06080 PF07702 UTRA domain SPYCW_RS06080 PF00392 Bacterial regulatory proteins, gntR family SPYCW_RS06090 PF00854 POT family SPYCW_RS06095 PF01979 Amidohydrolase family SPYCW_RS06100 PF01979 Amidohydrolase family SPYCW_RS06115 PF00248 Aldo/keto reductase family SPYCW_RS06125 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPYCW_RS06125 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPYCW_RS06125 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPYCW_RS06125 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPYCW_RS06130 PF06906 Protein of unknown function (DUF1272) SPYCW_RS06135 PF08543 Phosphomethylpyrimidine kinase SPYCW_RS06135 PF02581 Thiamine monophosphate synthase SPYCW_RS06140 PF01351 Ribonuclease HII SPYCW_RS06145 PF00106 short chain dehydrogenase SPYCW_RS06150 PF01555 DNA methylase SPYCW_RS06150 PF18755 Restriction Enzyme Adenine Methylase Associated SPYCW_RS06155 PF00809 Pterin binding enzyme SPYCW_RS06170 PF02954 Bacterial regulatory protein, Fis family SPYCW_RS06170 PF00072 Response regulator receiver domain SPYCW_RS06170 PF00158 Sigma-54 interaction domain SPYCW_RS06180 PF05222 Alanine dehydrogenase/PNT, N-terminal domain SPYCW_RS06180 PF01262 Alanine dehydrogenase/PNT, C-terminal domain SPYCW_RS06185 PF02469 Fasciclin domain SPYCW_RS06190 PF02469 Fasciclin domain SPYCW_RS06195 PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch SPYCW_RS06200 PF02233 NAD(P) transhydrogenase beta subunit SPYCW_RS06205 PF01177 Asp/Glu/Hydantoin racemase SPYCW_RS06225 PF13417 Glutathione S-transferase, N-terminal domain SPYCW_RS06255 PF13419 Haloacid dehalogenase-like hydrolase SPYCW_RS06260 PF00132 Bacterial transferase hexapeptide (six repeats) SPYCW_RS06260 PF14602 Hexapeptide repeat of succinyl-transferase SPYCW_RS06260 PF12804 MobA-like NTP transferase domain SPYCW_RS06285 PF01380 SIS domain SPYCW_RS06305 PF01738 Dienelactone hydrolase family SPYCW_RS06315 PF00248 Aldo/keto reductase family SPYCW_RS06325 PF01037 Lrp/AsnC ligand binding domain SPYCW_RS06330 PF00296 Luciferase-like monooxygenase SPYCW_RS06345 PF00202 Aminotransferase class-III SPYCW_RS06350 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPYCW_RS06350 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPYCW_RS06355 PF01430 Hsp33 protein SPYCW_RS06365 PF06508 Queuosine biosynthesis protein QueC SPYCW_RS06380 PF03099 Biotin/lipoate A/B protein ligase family SPYCW_RS06395 PF01218 Coproporphyrinogen III oxidase SPYCW_RS06400 PF00588 SpoU rRNA Methylase family SPYCW_RS06405 PF00355 Rieske [2Fe-2S] domain SPYCW_RS06405 PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SPYCW_RS06410 PF00033 Cytochrome b/b6/petB SPYCW_RS06410 PF00032 Cytochrome b(C-terminal)/b6/petD SPYCW_RS06415 PF02167 Cytochrome C1 family SPYCW_RS06420 PF00156 Phosphoribosyl transferase domain SPYCW_RS06450 PF02424 ApbE family SPYCW_RS06455 PF18331 PKHD-type hydroxylase C-terminal domain SPYCW_RS06455 PF13640 2OG-Fe(II) oxygenase superfamily SPYCW_RS06460 PF00593 TonB dependent receptor SPYCW_RS06460 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS06470 PF00561 alpha/beta hydrolase fold SPYCW_RS06485 PF00072 Response regulator receiver domain SPYCW_RS06500 PF04002 RadC-like JAB domain SPYCW_RS06505 PF00303 Thymidylate synthase SPYCW_RS06510 PF00676 Dehydrogenase E1 component SPYCW_RS06510 PF12573 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal SPYCW_RS06515 PF02780 Transketolase, C-terminal domain SPYCW_RS06515 PF02779 Transketolase, pyrimidine binding domain SPYCW_RS06520 PF02817 e3 binding domain SPYCW_RS06520 PF00364 Biotin-requiring enzyme SPYCW_RS06520 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SPYCW_RS06555 PF01594 AI-2E family transporter SPYCW_RS06570 PF01812 5-formyltetrahydrofolate cyclo-ligase family SPYCW_RS06585 PF00456 Transketolase, thiamine diphosphate binding domain SPYCW_RS06585 PF02780 Transketolase, C-terminal domain SPYCW_RS06585 PF02779 Transketolase, pyrimidine binding domain SPYCW_RS06590 PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain SPYCW_RS06590 PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SPYCW_RS06595 PF00162 Phosphoglycerate kinase SPYCW_RS06600 PF00274 Fructose-bisphosphate aldolase class-I SPYCW_RS06605 PF01596 O-methyltransferase SPYCW_RS06615 PF02581 Thiamine monophosphate synthase SPYCW_RS06620 PF03169 OPT oligopeptide transporter protein SPYCW_RS06625 PF09285 Elongation factor P, C-terminal SPYCW_RS06625 PF08207 Elongation factor P (EF-P) KOW-like domain SPYCW_RS06625 PF01132 Elongation factor P (EF-P) OB domain SPYCW_RS06630 PF00459 Inositol monophosphatase family SPYCW_RS06645 PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 SPYCW_RS06650 PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit SPYCW_RS06655 PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit SPYCW_RS06660 PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SPYCW_RS06675 PF10531 SLBB domain SPYCW_RS06675 PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit SPYCW_RS06675 PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SPYCW_RS06685 PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region SPYCW_RS06685 PF00384 Molybdopterin oxidoreductase SPYCW_RS06685 PF09326 NADH-ubiquinone oxidoreductase subunit G, C-terminal SPYCW_RS06690 PF00146 NADH dehydrogenase SPYCW_RS06695 PF12838 4Fe-4S dicluster domain SPYCW_RS06700 PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SPYCW_RS06705 PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SPYCW_RS06710 PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus SPYCW_RS06710 PF00361 Proton-conducting membrane transporter SPYCW_RS06715 PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus SPYCW_RS06715 PF00361 Proton-conducting membrane transporter SPYCW_RS06720 PF00361 Proton-conducting membrane transporter SPYCW_RS06725 PF02237 Biotin protein ligase C terminal domain SPYCW_RS06725 PF08279 HTH domain SPYCW_RS06725 PF03099 Biotin/lipoate A/B protein ligase family SPYCW_RS06730 PF03309 Type III pantothenate kinase SPYCW_RS06735 PF12706 Beta-lactamase superfamily domain SPYCW_RS06735 PF17770 Ribonuclease J C-terminal domain SPYCW_RS06735 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SPYCW_RS06765 PF01037 Lrp/AsnC ligand binding domain SPYCW_RS06770 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS06770 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS06790 PF01546 Peptidase family M20/M25/M40 SPYCW_RS06790 PF07687 Peptidase dimerisation domain SPYCW_RS06810 PF00005 ABC transporter SPYCW_RS06810 PF12848 ABC transporter SPYCW_RS06830 PF00484 Carbonic anhydrase SPYCW_RS06835 PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family SPYCW_RS06835 PF04055 Radical SAM superfamily SPYCW_RS06840 PF03364 Polyketide cyclase / dehydrase and lipid transport SPYCW_RS06845 PF02464 Competence-damaged protein SPYCW_RS06845 PF18146 Damage-inducible protein CinA KH domain SPYCW_RS06845 PF00994 Probable molybdopterin binding domain SPYCW_RS06850 PF02542 YgbB family SPYCW_RS06850 PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SPYCW_RS06855 PF01207 Dihydrouridine synthase (Dus) SPYCW_RS06860 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS06860 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS06860 PF00989 PAS fold SPYCW_RS06865 PF00072 Response regulator receiver domain SPYCW_RS06865 PF02954 Bacterial regulatory protein, Fis family SPYCW_RS06865 PF00158 Sigma-54 interaction domain SPYCW_RS06870 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS06870 PF00989 PAS fold SPYCW_RS06870 PF00672 HAMP domain SPYCW_RS06870 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS06875 PF00158 Sigma-54 interaction domain SPYCW_RS06875 PF02954 Bacterial regulatory protein, Fis family SPYCW_RS06875 PF00072 Response regulator receiver domain SPYCW_RS06880 PF17209 Hfq protein SPYCW_RS06885 PF16360 GTP-binding GTPase Middle Region SPYCW_RS06885 PF13167 GTP-binding GTPase N-terminal SPYCW_RS06885 PF01926 50S ribosome-binding GTPase SPYCW_RS06890 PF03819 MazG nucleotide pyrophosphohydrolase domain SPYCW_RS06900 PF01026 TatD related DNase SPYCW_RS06905 PF09334 tRNA synthetases class I (M) SPYCW_RS06905 PF08264 Anticodon-binding domain of tRNA SPYCW_RS06910 PF09115 DNA polymerase III, delta subunit, C terminal SPYCW_RS06915 PF02223 Thymidylate kinase SPYCW_RS06920 PF07943 Penicillin-binding protein 5, C-terminal domain SPYCW_RS06920 PF00768 D-alanyl-D-alanine carboxypeptidase SPYCW_RS06925 PF05036 Sporulation related domain SPYCW_RS06925 PF03330 Lytic transglycolase SPYCW_RS06930 PF13406 Transglycosylase SLT domain SPYCW_RS06960 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS06960 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS06960 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS06965 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS06965 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS06965 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS06970 PF12706 Beta-lactamase superfamily domain SPYCW_RS06990 PF02798 Glutathione S-transferase, N-terminal domain SPYCW_RS06995 PF02515 CoA-transferase family III SPYCW_RS07000 PF00326 Prolyl oligopeptidase family SPYCW_RS07000 PF07676 WD40-like Beta Propeller Repeat SPYCW_RS07025 PF01061 ABC-2 type transporter SPYCW_RS07045 PF00204 DNA gyrase B SPYCW_RS07045 PF00986 DNA gyrase B subunit, carboxyl terminus SPYCW_RS07045 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS07045 PF01751 Toprim domain SPYCW_RS07055 PF03466 LysR substrate binding domain SPYCW_RS07055 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS07060 PF04379 ApaG domain SPYCW_RS07065 PF01053 Cys/Met metabolism PLP-dependent enzyme SPYCW_RS07070 PF00180 Isocitrate/isopropylmalate dehydrogenase SPYCW_RS07075 PF11967 Recombination protein O N terminal SPYCW_RS07075 PF02565 Recombination protein O C terminal SPYCW_RS07085 PF02151 UvrB/uvrC motif SPYCW_RS07085 PF08459 UvrC Helix-hairpin-helix N-terminal SPYCW_RS07085 PF01541 GIY-YIG catalytic domain SPYCW_RS07090 PF00106 short chain dehydrogenase SPYCW_RS07095 PF00430 ATP synthase B/B' CF(0) SPYCW_RS07100 PF00430 ATP synthase B/B' CF(0) SPYCW_RS07105 PF00137 ATP synthase subunit C SPYCW_RS07110 PF00119 ATP synthase A chain SPYCW_RS07135 PF04002 RadC-like JAB domain SPYCW_RS07150 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPYCW_RS07150 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPYCW_RS07150 PF14579 Helix-hairpin-helix motif SPYCW_RS07150 PF02811 PHP domain SPYCW_RS07150 PF00929 Exonuclease SPYCW_RS07175 PF08401 Domain of unknown function (DUF1738) SPYCW_RS07175 PF18818 Metallopeptidase superfamily domain SPYCW_RS07175 PF13362 Toprim domain SPYCW_RS07180 PF02195 ParB-like nuclease domain SPYCW_RS07180 PF17762 HTH domain found in ParB protein SPYCW_RS07220 PF01850 PIN domain SPYCW_RS07230 PF05284 Protein of unknown function (DUF736) SPYCW_RS07280 PF13614 AAA domain SPYCW_RS07300 PF05284 Protein of unknown function (DUF736) SPYCW_RS07305 PF01464 Transglycosylase SLT domain SPYCW_RS07315 PF02534 Type IV secretory system Conjugative DNA transfer SPYCW_RS07325 PF00437 Type II/IV secretion system protein SPYCW_RS07340 PF03135 CagE, TrbE, VirB family, component of type IV transporter system SPYCW_RS07355 PF04610 TrbL/VirB6 plasmid conjugal transfer protein SPYCW_RS07370 PF03743 Bacterial conjugation TrbI-like protein SPYCW_RS07380 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS07380 PF03466 LysR substrate binding domain SPYCW_RS07410 PF00271 Helicase conserved C-terminal domain SPYCW_RS07410 PF00176 SNF2 family N-terminal domain SPYCW_RS07425 PF12705 PD-(D/E)XK nuclease superfamily SPYCW_RS07425 PF00580 UvrD/REP helicase N-terminal domain SPYCW_RS07425 PF13361 UvrD-like helicase C-terminal domain SPYCW_RS07430 PF17757 UvrB interaction domain SPYCW_RS07430 PF12344 Ultra-violet resistance protein B SPYCW_RS07430 PF02151 UvrB/uvrC motif SPYCW_RS07430 PF04851 Type III restriction enzyme, res subunit SPYCW_RS07430 PF00271 Helicase conserved C-terminal domain SPYCW_RS07470 PF02798 Glutathione S-transferase, N-terminal domain SPYCW_RS07475 PF00043 Glutathione S-transferase, C-terminal domain SPYCW_RS07475 PF02798 Glutathione S-transferase, N-terminal domain SPYCW_RS07490 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS07490 PF17151 Periplasmic sensor domain SPYCW_RS07495 PF00724 NADH:flavin oxidoreductase / NADH oxidase family SPYCW_RS07500 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS07515 PF01625 Peptide methionine sulfoxide reductase SPYCW_RS07520 PF01641 SelR domain SPYCW_RS07525 PF03466 LysR substrate binding domain SPYCW_RS07525 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS07530 PF02371 Transposase IS116/IS110/IS902 family SPYCW_RS07530 PF01548 Transposase SPYCW_RS07535 PF00589 Phage integrase family SPYCW_RS07535 PF13356 Arm DNA-binding domain SPYCW_RS07610 PF01292 Prokaryotic cytochrome b561 SPYCW_RS07615 PF00174 Oxidoreductase molybdopterin binding domain SPYCW_RS07640 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS07640 PF03466 LysR substrate binding domain SPYCW_RS07650 PF00795 Carbon-nitrogen hydrolase SPYCW_RS07665 PF01641 SelR domain SPYCW_RS07675 PF01625 Peptide methionine sulfoxide reductase SPYCW_RS07680 PF01641 SelR domain SPYCW_RS07685 PF00893 Small Multidrug Resistance protein SPYCW_RS07690 PF04224 Protein of unknown function, DUF417 SPYCW_RS07695 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS07695 PF00724 NADH:flavin oxidoreductase / NADH oxidase family SPYCW_RS07700 PF01042 Endoribonuclease L-PSP SPYCW_RS07705 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS07705 PF03466 LysR substrate binding domain SPYCW_RS07715 PF01066 CDP-alcohol phosphatidyltransferase SPYCW_RS07720 PF07662 Na+ dependent nucleoside transporter C-terminus SPYCW_RS07720 PF01773 Na+ dependent nucleoside transporter N-terminus SPYCW_RS07745 PF01625 Peptide methionine sulfoxide reductase SPYCW_RS07750 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPYCW_RS07750 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS07765 PF03449 Transcription elongation factor, N-terminal SPYCW_RS07765 PF01272 Transcription elongation factor, GreA/GreB, C-term SPYCW_RS07780 PF00206 Lyase SPYCW_RS07780 PF10397 Adenylosuccinate lyase C-terminus SPYCW_RS07790 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SPYCW_RS07795 PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SPYCW_RS07800 PF00291 Pyridoxal-phosphate dependent enzyme SPYCW_RS07805 PF00290 Tryptophan synthase alpha chain SPYCW_RS07810 PF01039 Carboxyl transferase domain SPYCW_RS07810 PF17848 Acetyl-coA carboxylase zinc finger domain SPYCW_RS07815 PF08245 Mur ligase middle domain SPYCW_RS07815 PF02875 Mur ligase family, glutamate ligase domain SPYCW_RS07820 PF07690 Major Facilitator Superfamily SPYCW_RS07825 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS07825 PF00072 Response regulator receiver domain SPYCW_RS07830 PF01479 S4 domain SPYCW_RS07830 PF00849 RNA pseudouridylate synthase SPYCW_RS07840 PF00083 Sugar (and other) transporter SPYCW_RS07840 PF07690 Major Facilitator Superfamily SPYCW_RS07845 PF00580 UvrD/REP helicase N-terminal domain SPYCW_RS07845 PF13361 UvrD-like helicase C-terminal domain SPYCW_RS07860 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS07860 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS07860 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS07870 PF00107 Zinc-binding dehydrogenase SPYCW_RS07870 PF16884 N-terminal domain of oxidoreductase SPYCW_RS07875 PF00271 Helicase conserved C-terminal domain SPYCW_RS07875 PF00270 DEAD/DEAH box helicase SPYCW_RS07885 PF02913 FAD linked oxidases, C-terminal domain SPYCW_RS07885 PF01565 FAD binding domain SPYCW_RS07905 PF01029 NusB family SPYCW_RS07905 PF01189 16S rRNA methyltransferase RsmB/F SPYCW_RS07915 PF07690 Major Facilitator Superfamily SPYCW_RS07925 PF00291 Pyridoxal-phosphate dependent enzyme SPYCW_RS07935 PF00578 AhpC/TSA family SPYCW_RS07945 PF02668 Taurine catabolism dioxygenase TauD, TfdA family SPYCW_RS07955 PF01134 Glucose inhibited division protein A SPYCW_RS07965 PF03466 LysR substrate binding domain SPYCW_RS07965 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS07970 PF02391 MoaE protein SPYCW_RS07980 PF01066 CDP-alcohol phosphatidyltransferase SPYCW_RS07995 PF00459 Inositol monophosphatase family SPYCW_RS08000 PF00009 Elongation factor Tu GTP binding domain SPYCW_RS08005 PF01507 Phosphoadenosine phosphosulfate reductase family SPYCW_RS08010 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS08010 PF03466 LysR substrate binding domain SPYCW_RS08015 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS08015 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS08015 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS08030 PF01039 Carboxyl transferase domain SPYCW_RS08035 PF01337 Barstar (barnase inhibitor) SPYCW_RS08040 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPYCW_RS08040 PF00364 Biotin-requiring enzyme SPYCW_RS08040 PF18140 Propionyl-coenzyme A carboxylase BT domain SPYCW_RS08040 PF00289 Biotin carboxylase, N-terminal domain SPYCW_RS08040 PF02785 Biotin carboxylase C-terminal domain SPYCW_RS08045 PF01575 MaoC like domain SPYCW_RS08050 PF03328 HpcH/HpaI aldolase/citrate lyase family SPYCW_RS08060 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS08060 PF12806 Acetyl-CoA dehydrogenase C-terminal like SPYCW_RS08060 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS08060 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS08065 PF13411 MerR HTH family regulatory protein SPYCW_RS08075 PF01502 Phosphoribosyl-AMP cyclohydrolase SPYCW_RS08080 PF13537 Glutamine amidotransferase domain SPYCW_RS08080 PF00156 Phosphoribosyl transferase domain SPYCW_RS08085 PF00106 short chain dehydrogenase SPYCW_RS08095 PF00144 Beta-lactamase SPYCW_RS08105 PF03441 FAD binding domain of DNA photolyase SPYCW_RS08105 PF00875 DNA photolyase SPYCW_RS08115 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPYCW_RS08120 PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SPYCW_RS08120 PF17147 Pyruvate:ferredoxin oxidoreductase core domain II SPYCW_RS08120 PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase SPYCW_RS08125 PF07859 alpha/beta hydrolase fold SPYCW_RS08130 PF00293 NUDIX domain SPYCW_RS08135 PF03167 Uracil DNA glycosylase superfamily SPYCW_RS08140 PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) SPYCW_RS08150 PF01370 NAD dependent epimerase/dehydratase family SPYCW_RS08155 PF16363 GDP-mannose 4,6 dehydratase SPYCW_RS08160 PF01169 Uncharacterized protein family UPF0016 SPYCW_RS08175 PF17243 POTRA domain TamA domain 1 SPYCW_RS08175 PF07244 Surface antigen variable number repeat SPYCW_RS08175 PF01103 Surface antigen SPYCW_RS08180 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain SPYCW_RS08180 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPYCW_RS08180 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SPYCW_RS08185 PF02696 Uncharacterized ACR, YdiU/UPF0061 family SPYCW_RS08190 PF02719 Polysaccharide biosynthesis protein SPYCW_RS08195 PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family SPYCW_RS08210 PF02397 Bacterial sugar transferase SPYCW_RS08220 PF01380 SIS domain SPYCW_RS08235 PF13439 Glycosyltransferase Family 4 SPYCW_RS08235 PF00534 Glycosyl transferases group 1 SPYCW_RS08250 PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family SPYCW_RS08260 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPYCW_RS08260 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain SPYCW_RS08260 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SPYCW_RS08270 PF05717 IS66 Orf2 like protein SPYCW_RS08275 PF13005 zinc-finger binding domain of transposase IS66 SPYCW_RS08275 PF13817 IS66 C-terminal element SPYCW_RS08275 PF13007 Transposase C of IS166 homeodomain SPYCW_RS08275 PF03050 Transposase IS66 family SPYCW_RS08290 PF02706 Chain length determinant protein SPYCW_RS08290 PF13614 AAA domain SPYCW_RS08290 PF13807 G-rich domain on putative tyrosine kinase SPYCW_RS08310 PF00149 Calcineurin-like phosphoesterase SPYCW_RS08315 PF02350 UDP-N-acetylglucosamine 2-epimerase SPYCW_RS08320 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SPYCW_RS08320 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPYCW_RS08320 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain SPYCW_RS08325 PF01238 Phosphomannose isomerase type I SPYCW_RS08330 PF00227 Proteasome subunit SPYCW_RS08335 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS08335 PF07724 AAA domain (Cdc48 subfamily) SPYCW_RS08350 PF01171 PP-loop family SPYCW_RS08355 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS08355 PF17862 AAA+ lid domain SPYCW_RS08355 PF01434 Peptidase family M41 SPYCW_RS08375 PF01192 RNA polymerase Rpb6 SPYCW_RS08380 PF13396 Phospholipase_D-nuclease N-terminal SPYCW_RS08380 PF13091 PLD-like domain SPYCW_RS08395 PF17862 AAA+ lid domain SPYCW_RS08395 PF01434 Peptidase family M41 SPYCW_RS08395 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS08400 PF03466 LysR substrate binding domain SPYCW_RS08400 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS08440 PF05717 IS66 Orf2 like protein SPYCW_RS08445 PF13817 IS66 C-terminal element SPYCW_RS08445 PF03050 Transposase IS66 family SPYCW_RS08445 PF13007 Transposase C of IS166 homeodomain SPYCW_RS08445 PF13005 zinc-finger binding domain of transposase IS66 SPYCW_RS08465 PF02661 Fic/DOC family SPYCW_RS08470 PF04239 Protein of unknown function (DUF421) SPYCW_RS08480 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPYCW_RS08480 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS08490 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS08490 PF03466 LysR substrate binding domain SPYCW_RS08500 PF01641 SelR domain SPYCW_RS08505 PF01625 Peptide methionine sulfoxide reductase SPYCW_RS08510 PF00462 Glutaredoxin SPYCW_RS08525 PF12833 Helix-turn-helix domain SPYCW_RS08525 PF07883 Cupin domain SPYCW_RS08530 PF00210 Ferritin-like domain SPYCW_RS08545 PF02798 Glutathione S-transferase, N-terminal domain SPYCW_RS08550 PF01544 CorA-like Mg2+ transporter protein SPYCW_RS08555 PF02803 Thiolase, C-terminal domain SPYCW_RS08555 PF00108 Thiolase, N-terminal domain SPYCW_RS08575 PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) SPYCW_RS08580 PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain SPYCW_RS08580 PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SPYCW_RS08600 PF01695 IstB-like ATP binding protein SPYCW_RS08605 PF00665 Integrase core domain SPYCW_RS08610 PF02308 MgtC family SPYCW_RS08660 PF00665 Integrase core domain SPYCW_RS08695 PF01541 GIY-YIG catalytic domain SPYCW_RS08710 PF01613 Flavin reductase like domain SPYCW_RS08715 PF03060 Nitronate monooxygenase SPYCW_RS08720 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS08720 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS08720 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS08725 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS08725 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS08725 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS08730 PF00106 short chain dehydrogenase SPYCW_RS08735 PF02803 Thiolase, C-terminal domain SPYCW_RS08735 PF00108 Thiolase, N-terminal domain SPYCW_RS08740 PF02515 CoA-transferase family III SPYCW_RS08745 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS08745 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS08745 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS08750 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS08750 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS08750 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS08755 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS08760 PF13350 Tyrosine phosphatase family SPYCW_RS08765 PF01979 Amidohydrolase family SPYCW_RS08775 PF01063 Amino-transferase class IV SPYCW_RS08785 PF01569 PAP2 superfamily SPYCW_RS08795 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS08795 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPYCW_RS08800 PF04480 Protein of unknown function (DUF559) SPYCW_RS08805 PF02817 e3 binding domain SPYCW_RS08805 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SPYCW_RS08805 PF00364 Biotin-requiring enzyme SPYCW_RS08825 PF08206 Ribonuclease B OB domain SPYCW_RS08825 PF00773 RNB domain SPYCW_RS08825 PF17876 Cold shock domain SPYCW_RS08825 PF00575 S1 RNA binding domain SPYCW_RS08825 PF08461 Ribonuclease R winged-helix domain SPYCW_RS08835 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPYCW_RS08835 PF03129 Anticodon binding domain SPYCW_RS08840 PF05233 PHB accumulation regulatory domain SPYCW_RS08840 PF07879 PHB/PHA accumulation regulator DNA-binding domain SPYCW_RS08845 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS08845 PF00593 TonB dependent receptor SPYCW_RS08860 PF00842 Alanine racemase, C-terminal domain SPYCW_RS08860 PF01168 Alanine racemase, N-terminal domain SPYCW_RS08865 PF00083 Sugar (and other) transporter SPYCW_RS08865 PF07690 Major Facilitator Superfamily SPYCW_RS08870 PF04199 Putative cyclase SPYCW_RS08885 PF01588 Putative tRNA binding domain SPYCW_RS08905 PF06968 Biotin and Thiamin Synthesis associated domain SPYCW_RS08905 PF04055 Radical SAM superfamily SPYCW_RS08910 PF02310 B12 binding domain SPYCW_RS08910 PF01642 Methylmalonyl-CoA mutase SPYCW_RS08920 PF01039 Carboxyl transferase domain SPYCW_RS08925 PF06114 IrrE N-terminal-like domain SPYCW_RS08925 PF01381 Helix-turn-helix SPYCW_RS08925 PF09856 Predicted transcriptional regulator (DUF2083) SPYCW_RS08930 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS08930 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPYCW_RS08935 PF00342 Phosphoglucose isomerase SPYCW_RS08940 PF10502 Signal peptidase, peptidase S26 SPYCW_RS08945 PF00035 Double-stranded RNA binding motif SPYCW_RS08945 PF14622 Ribonuclease-III-like SPYCW_RS08950 PF07650 KH domain SPYCW_RS08950 PF01926 50S ribosome-binding GTPase SPYCW_RS08965 PF01396 Topoisomerase DNA binding C4 zinc finger SPYCW_RS08965 PF13368 Topoisomerase C-terminal repeat SPYCW_RS08965 PF01131 DNA topoisomerase SPYCW_RS08965 PF01751 Toprim domain SPYCW_RS08985 PF17782 DprA winged helix domain SPYCW_RS08985 PF02481 DNA recombination-mediator protein A SPYCW_RS08990 PF02660 Glycerol-3-phosphate acyltransferase SPYCW_RS08995 PF01177 Asp/Glu/Hydantoin racemase SPYCW_RS09005 PF00155 Aminotransferase class I and II SPYCW_RS09015 PF00881 Nitroreductase family SPYCW_RS09020 PF02469 Fasciclin domain SPYCW_RS09030 PF04542 Sigma-70 region 2 SPYCW_RS09030 PF04545 Sigma-70, region 4 SPYCW_RS09035 PF00583 Acetyltransferase (GNAT) family SPYCW_RS09045 PF00291 Pyridoxal-phosphate dependent enzyme SPYCW_RS09050 PF03435 Saccharopine dehydrogenase NADP binding domain SPYCW_RS09050 PF16653 Saccharopine dehydrogenase C-terminal domain SPYCW_RS09055 PF12146 Serine aminopeptidase, S33 SPYCW_RS09065 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPYCW_RS09070 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS09105 PF02515 CoA-transferase family III SPYCW_RS09120 PF05958 tRNA (Uracil-5-)-methyltransferase SPYCW_RS09125 PF01256 Carbohydrate kinase SPYCW_RS09125 PF03853 YjeF-related protein N-terminus SPYCW_RS09135 PF00920 Dehydratase family SPYCW_RS09145 PF00288 GHMP kinases N terminal domain SPYCW_RS09145 PF08544 GHMP kinases C terminal SPYCW_RS09170 PF00994 Probable molybdopterin binding domain SPYCW_RS09185 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS09185 PF00501 AMP-binding enzyme SPYCW_RS09190 PF02811 PHP domain SPYCW_RS09190 PF14579 Helix-hairpin-helix motif SPYCW_RS09190 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPYCW_RS09190 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPYCW_RS09195 PF00255 Glutathione peroxidase SPYCW_RS09205 PF00005 ABC transporter SPYCW_RS09210 PF02687 FtsX-like permease family SPYCW_RS09210 PF12704 MacB-like periplasmic core domain SPYCW_RS09215 PF00027 Cyclic nucleotide-binding domain SPYCW_RS09215 PF13545 Crp-like helix-turn-helix domain SPYCW_RS09220 PF00117 Glutamine amidotransferase class-I SPYCW_RS09220 PF06418 CTP synthase N-terminus SPYCW_RS09230 PF00121 Triosephosphate isomerase SPYCW_RS09240 PF00425 chorismate binding enzyme SPYCW_RS09240 PF04715 Anthranilate synthase component I, N terminal region SPYCW_RS09245 PF00561 alpha/beta hydrolase fold SPYCW_RS09250 PF00117 Glutamine amidotransferase class-I SPYCW_RS09255 PF00591 Glycosyl transferase family, a/b domain SPYCW_RS09255 PF02885 Glycosyl transferase family, helical bundle domain SPYCW_RS09260 PF00218 Indole-3-glycerol phosphate synthase SPYCW_RS09265 PF01967 MoaC family SPYCW_RS09270 PF03453 MoeA N-terminal region (domain I and II) SPYCW_RS09270 PF03454 MoeA C-terminal region (domain IV) SPYCW_RS09270 PF00994 Probable molybdopterin binding domain SPYCW_RS09275 PF00717 Peptidase S24-like SPYCW_RS09275 PF01726 LexA DNA binding domain SPYCW_RS09280 PF00753 Metallo-beta-lactamase superfamily SPYCW_RS09280 PF03772 Competence protein SPYCW_RS09285 PF00749 tRNA synthetases class I (E and Q), catalytic domain SPYCW_RS09290 PF00285 Citrate synthase, C-terminal domain SPYCW_RS09300 PF16736 Single Cache-like SPYCW_RS09300 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS09300 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS09300 PF00989 PAS fold SPYCW_RS09315 PF00106 short chain dehydrogenase SPYCW_RS09320 PF03989 DNA gyrase C-terminal domain, beta-propeller SPYCW_RS09320 PF00521 DNA gyrase/topoisomerase IV, subunit A SPYCW_RS09330 PF01979 Amidohydrolase family SPYCW_RS09345 PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain SPYCW_RS09345 PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain SPYCW_RS09350 PF03060 Nitronate monooxygenase SPYCW_RS09355 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPYCW_RS09360 PF01769 Divalent cation transporter SPYCW_RS09360 PF00571 CBS domain SPYCW_RS09360 PF03448 MgtE intracellular N domain SPYCW_RS09365 PF08085 Entericidin EcnA/B family SPYCW_RS09370 PF00902 Sec-independent protein translocase protein (TatC) SPYCW_RS09375 PF02416 mttA/Hcf106 family SPYCW_RS09380 PF02416 mttA/Hcf106 family SPYCW_RS09385 PF04079 Segregation and condensation complex subunit ScpB SPYCW_RS09390 PF02616 Segregation and condensation protein ScpA SPYCW_RS09395 PF00933 Glycosyl hydrolase family 3 N terminal domain SPYCW_RS09405 PF03485 Arginyl tRNA synthetase N terminal domain SPYCW_RS09405 PF05746 DALR anticodon binding domain SPYCW_RS09405 PF00133 tRNA synthetases class I (I, L, M and V) SPYCW_RS09405 PF00750 tRNA synthetases class I (R) SPYCW_RS09415 PF02401 LytB protein SPYCW_RS09420 PF01636 Phosphotransferase enzyme family SPYCW_RS09425 PF00075 RNase H SPYCW_RS09430 PF07411 Domain of unknown function (DUF1508) SPYCW_RS09435 PF01266 FAD dependent oxidoreductase SPYCW_RS09435 PF05430 S-adenosyl-L-methionine-dependent methyltransferase SPYCW_RS09450 PF13629 Pilus formation protein N terminal region SPYCW_RS09450 PF00263 Bacterial type II and III secretion system protein SPYCW_RS09450 PF04972 BON domain SPYCW_RS09485 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS09485 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS09485 PF11808 Phosphate regulon sensor protein PhoR SPYCW_RS09485 PF00989 PAS fold SPYCW_RS09490 PF00202 Aminotransferase class-III SPYCW_RS09495 PF00120 Glutamine synthetase, catalytic domain SPYCW_RS09500 PF01266 FAD dependent oxidoreductase SPYCW_RS09505 PF00202 Aminotransferase class-III SPYCW_RS09510 PF00120 Glutamine synthetase, catalytic domain SPYCW_RS09515 PF13416 Bacterial extracellular solute-binding protein SPYCW_RS09520 PF00528 Binding-protein-dependent transport system inner membrane component SPYCW_RS09525 PF00528 Binding-protein-dependent transport system inner membrane component SPYCW_RS09535 PF08402 TOBE domain SPYCW_RS09535 PF00005 ABC transporter SPYCW_RS09540 PF05661 Protein of unknown function (DUF808) SPYCW_RS09545 PF00202 Aminotransferase class-III SPYCW_RS09550 PF07722 Peptidase C26 SPYCW_RS09570 PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SPYCW_RS09570 PF00391 PEP-utilising enzyme, mobile domain SPYCW_RS09570 PF02896 PEP-utilising enzyme, TIM barrel domain SPYCW_RS09575 PF05746 DALR anticodon binding domain SPYCW_RS09575 PF02092 Glycyl-tRNA synthetase beta subunit SPYCW_RS09580 PF02091 Glycyl-tRNA synthetase alpha subunit SPYCW_RS09605 PF14693 Ribosomal protein TL5, C-terminal domain SPYCW_RS09605 PF01386 Ribosomal L25p family SPYCW_RS09610 PF01195 Peptidyl-tRNA hydrolase SPYCW_RS09615 PF00106 short chain dehydrogenase SPYCW_RS09630 PF06071 Protein of unknown function (DUF933) SPYCW_RS09630 PF01926 50S ribosome-binding GTPase SPYCW_RS09640 PF09278 MerR, DNA binding SPYCW_RS09640 PF00376 MerR family regulatory protein SPYCW_RS09660 PF09423 PhoD-like phosphatase SPYCW_RS09660 PF16655 PhoD-like phosphatase, N-terminal domain SPYCW_RS09670 PF08676 MutL C terminal dimerisation domain SPYCW_RS09670 PF01119 DNA mismatch repair protein, C-terminal domain SPYCW_RS09680 PF04085 rod shape-determining protein MreC SPYCW_RS09690 PF00905 Penicillin binding protein transpeptidase domain SPYCW_RS09690 PF03717 Penicillin-binding Protein dimerisation domain SPYCW_RS09695 PF01098 Cell cycle protein SPYCW_RS09765 PF12705 PD-(D/E)XK nuclease superfamily SPYCW_RS09765 PF00580 UvrD/REP helicase N-terminal domain SPYCW_RS09765 PF13361 UvrD-like helicase C-terminal domain SPYCW_RS09780 PF00271 Helicase conserved C-terminal domain SPYCW_RS09780 PF00176 SNF2 family N-terminal domain SPYCW_RS09885 PF07057 DNA helicase TraI SPYCW_RS09885 PF18340 DNA relaxase TraI 2B/2B-like domain SPYCW_RS09885 PF18272 single-stranded DNA binding TraI N-terminal subdomain SPYCW_RS09885 PF08751 TrwC relaxase SPYCW_RS09915 PF00436 Single-strand binding protein family SPYCW_RS09940 PF08401 Domain of unknown function (DUF1738) SPYCW_RS09940 PF18818 Metallopeptidase superfamily domain SPYCW_RS09950 PF00595 PDZ domain SPYCW_RS09955 PF00011 Hsp20/alpha crystallin family SPYCW_RS09960 PF00011 Hsp20/alpha crystallin family SPYCW_RS09970 PF13091 PLD-like domain SPYCW_RS09970 PF13396 Phospholipase_D-nuclease N-terminal SPYCW_RS09975 PF02080 TrkA-C domain SPYCW_RS09975 PF00999 Sodium/hydrogen exchanger family SPYCW_RS09975 PF02254 TrkA-N domain SPYCW_RS09985 PF00011 Hsp20/alpha crystallin family SPYCW_RS10015 PF00210 Ferritin-like domain SPYCW_RS10035 PF01025 GrpE SPYCW_RS10040 PF00012 Hsp70 protein SPYCW_RS10050 PF00226 DnaJ domain SPYCW_RS10050 PF01556 DnaJ C terminal domain SPYCW_RS10055 PF00085 Thioredoxin SPYCW_RS10060 PF10431 C-terminal, D2-small domain, of ClpB protein SPYCW_RS10060 PF02861 Clp amino terminal domain, pathogenicity island component SPYCW_RS10060 PF07724 AAA domain (Cdc48 subfamily) SPYCW_RS10060 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS10060 PF17871 AAA lid domain SPYCW_RS10070 PF17269 Family of unknown function (DUF5335) SPYCW_RS10095 PF00924 Mechanosensitive ion channel SPYCW_RS10130 PF09722 Protein of unknown function (DUF2384) SPYCW_RS10145 PF01464 Transglycosylase SLT domain SPYCW_RS10145 PF10145 Phage-related minor tail protein SPYCW_RS10145 PF01551 Peptidase family M23 SPYCW_RS10155 PF02308 MgtC family SPYCW_RS10160 PF04055 Radical SAM superfamily SPYCW_RS10170 PF03597 Cytochrome oxidase maturation protein cbb3-type SPYCW_RS10185 PF12801 4Fe-4S binding domain SPYCW_RS10185 PF13746 4Fe-4S dicluster domain SPYCW_RS10185 PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase SPYCW_RS10190 PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP SPYCW_RS10190 PF13442 Cytochrome C oxidase, cbb3-type, subunit III SPYCW_RS10205 PF00115 Cytochrome C and Quinol oxidase polypeptide I SPYCW_RS10210 PF03922 OmpW family SPYCW_RS10215 PF13545 Crp-like helix-turn-helix domain SPYCW_RS10215 PF00027 Cyclic nucleotide-binding domain SPYCW_RS10245 PF00529 HlyD membrane-fusion protein of T1SS SPYCW_RS10245 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPYCW_RS10250 PF00005 ABC transporter SPYCW_RS10250 PF00664 ABC transporter transmembrane region SPYCW_RS10275 PF00353 RTX calcium-binding nonapeptide repeat (4 copies) SPYCW_RS10275 PF06594 Haemolysin-type calcium binding protein related domain SPYCW_RS10280 PF02321 Outer membrane efflux protein SPYCW_RS10285 PF00005 ABC transporter SPYCW_RS10285 PF00664 ABC transporter transmembrane region SPYCW_RS10285 PF03412 Peptidase C39 family SPYCW_RS10295 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPYCW_RS10295 PF00529 HlyD membrane-fusion protein of T1SS SPYCW_RS10300 PF00072 Response regulator receiver domain SPYCW_RS10300 PF00196 Bacterial regulatory proteins, luxR family SPYCW_RS10315 PF00144 Beta-lactamase SPYCW_RS10330 PF00593 TonB dependent receptor SPYCW_RS10330 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS10340 PF13378 Enolase C-terminal domain-like SPYCW_RS10340 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SPYCW_RS10345 PF00144 Beta-lactamase SPYCW_RS10355 PF07969 Amidohydrolase family SPYCW_RS10360 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS10375 PF14821 Threonine synthase N terminus SPYCW_RS10375 PF00291 Pyridoxal-phosphate dependent enzyme SPYCW_RS10390 PF00510 Cytochrome c oxidase subunit III SPYCW_RS10395 PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 SPYCW_RS10400 PF01040 UbiA prenyltransferase family SPYCW_RS10405 PF00115 Cytochrome C and Quinol oxidase polypeptide I SPYCW_RS10410 PF00116 Cytochrome C oxidase subunit II, periplasmic domain SPYCW_RS10410 PF02790 Cytochrome C oxidase subunit II, transmembrane domain SPYCW_RS10415 PF00156 Phosphoribosyl transferase domain SPYCW_RS10420 PF03740 Pyridoxal phosphate biosynthesis protein PdxJ SPYCW_RS10425 PF01648 4'-phosphopantetheinyl transferase superfamily SPYCW_RS10430 PF10502 Signal peptidase, peptidase S26 SPYCW_RS10435 PF01594 AI-2E family transporter SPYCW_RS10440 PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase SPYCW_RS10440 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPYCW_RS10455 PF01165 Ribosomal protein S21 SPYCW_RS10460 PF00596 Class II Aldolase and Adducin N-terminal domain SPYCW_RS10465 PF00111 2Fe-2S iron-sulfur cluster binding domain SPYCW_RS10465 PF01799 [2Fe-2S] binding domain SPYCW_RS10475 PF01979 Amidohydrolase family SPYCW_RS10480 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS10480 PF08447 PAS fold SPYCW_RS10480 PF00563 EAL domain SPYCW_RS10480 PF08448 PAS fold SPYCW_RS10500 PF01921 tRNA synthetases class I (K) SPYCW_RS10505 PF00698 Acyl transferase domain SPYCW_RS10505 PF00109 Beta-ketoacyl synthase, N-terminal domain SPYCW_RS10505 PF08659 KR domain SPYCW_RS10505 PF00107 Zinc-binding dehydrogenase SPYCW_RS10505 PF14765 Polyketide synthase dehydratase SPYCW_RS10505 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS10505 PF00550 Phosphopantetheine attachment site SPYCW_RS10505 PF16197 Ketoacyl-synthetase C-terminal extension SPYCW_RS10505 PF02801 Beta-ketoacyl synthase, C-terminal domain SPYCW_RS10520 PF06733 DEAD_2 SPYCW_RS10520 PF13307 Helicase C-terminal domain SPYCW_RS10525 PF00300 Histidine phosphatase superfamily (branch 1) SPYCW_RS10530 PF13411 MerR HTH family regulatory protein SPYCW_RS10535 PF00216 Bacterial DNA-binding protein SPYCW_RS10540 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SPYCW_RS10540 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SPYCW_RS10545 PF02504 Fatty acid synthesis protein SPYCW_RS10550 PF01783 Ribosomal L32p protein family SPYCW_RS10560 PF00753 Metallo-beta-lactamase superfamily SPYCW_RS10585 PF01979 Amidohydrolase family SPYCW_RS10590 PF00892 EamA-like transporter family SPYCW_RS10635 PF05690 Thiazole biosynthesis protein ThiG SPYCW_RS10640 PF05690 Thiazole biosynthesis protein ThiG SPYCW_RS10640 PF02597 ThiS family SPYCW_RS10655 PF01220 Dehydroquinase class II SPYCW_RS10660 PF00364 Biotin-requiring enzyme SPYCW_RS10665 PF02785 Biotin carboxylase C-terminal domain SPYCW_RS10665 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPYCW_RS10665 PF00289 Biotin carboxylase, N-terminal domain SPYCW_RS10675 PF05000 RNA polymerase Rpb1, domain 4 SPYCW_RS10675 PF04983 RNA polymerase Rpb1, domain 3 SPYCW_RS10675 PF00623 RNA polymerase Rpb1, domain 2 SPYCW_RS10675 PF04998 RNA polymerase Rpb1, domain 5 SPYCW_RS10675 PF04997 RNA polymerase Rpb1, domain 1 SPYCW_RS10680 PF04565 RNA polymerase Rpb2, domain 3 SPYCW_RS10680 PF04561 RNA polymerase Rpb2, domain 2 SPYCW_RS10680 PF04563 RNA polymerase beta subunit SPYCW_RS10680 PF10385 RNA polymerase beta subunit external 1 domain SPYCW_RS10680 PF04560 RNA polymerase Rpb2, domain 7 SPYCW_RS10680 PF00562 RNA polymerase Rpb2, domain 6 SPYCW_RS10690 PF01556 DnaJ C terminal domain SPYCW_RS10690 PF00684 DnaJ central domain SPYCW_RS10690 PF00226 DnaJ domain SPYCW_RS10695 PF03976 Polyphosphate kinase 2 (PPK2) SPYCW_RS10710 PF01336 OB-fold nucleic acid binding domain SPYCW_RS10710 PF00152 tRNA synthetases class II (D, K and N) SPYCW_RS10710 PF02938 GAD domain SPYCW_RS10720 PF01612 3'-5' exonuclease SPYCW_RS10720 PF00570 HRDC domain SPYCW_RS10725 PF02541 Ppx/GppA phosphatase family SPYCW_RS10730 PF13089 Polyphosphate kinase N-terminal domain SPYCW_RS10730 PF17941 Polyphosphate kinase C-terminal domain 1 SPYCW_RS10730 PF02503 Polyphosphate kinase middle domain SPYCW_RS10730 PF13090 Polyphosphate kinase C-terminal domain 2 SPYCW_RS10745 PF00586 AIR synthase related protein, N-terminal domain SPYCW_RS10745 PF02769 AIR synthase related protein, C-terminal domain SPYCW_RS10750 PF00551 Formyl transferase SPYCW_RS10755 PF00334 Nucleoside diphosphate kinase SPYCW_RS10770 PF00883 Cytosol aminopeptidase family, catalytic domain SPYCW_RS10770 PF02789 Cytosol aminopeptidase family, N-terminal domain SPYCW_RS10775 PF04453 LPS transport system D SPYCW_RS10780 PF09312 SurA N-terminal domain SPYCW_RS10780 PF00639 PPIC-type PPIASE domain SPYCW_RS10785 PF04166 Pyridoxal phosphate biosynthetic protein PdxA SPYCW_RS10790 PF00398 Ribosomal RNA adenine dimethylase SPYCW_RS10800 PF01029 NusB family SPYCW_RS10800 PF01189 16S rRNA methyltransferase RsmB/F SPYCW_RS10805 PF00478 IMP dehydrogenase / GMP reductase domain SPYCW_RS10805 PF00571 CBS domain SPYCW_RS10810 PF01638 HxlR-like helix-turn-helix SPYCW_RS10815 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS10815 PF00593 TonB dependent receptor SPYCW_RS10825 PF03055 Retinal pigment epithelial membrane protein SPYCW_RS10830 PF00501 AMP-binding enzyme SPYCW_RS10830 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS10835 PF00108 Thiolase, N-terminal domain SPYCW_RS10835 PF02803 Thiolase, C-terminal domain SPYCW_RS10840 PF02803 Thiolase, C-terminal domain SPYCW_RS10840 PF00108 Thiolase, N-terminal domain SPYCW_RS10845 PF00593 TonB dependent receptor SPYCW_RS10845 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS10850 PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP SPYCW_RS10860 PF01032 FecCD transport family SPYCW_RS10865 PF00005 ABC transporter SPYCW_RS10870 PF02838 Glycosyl hydrolase family 20, domain 2 SPYCW_RS10870 PF03173 Putative carbohydrate binding domain SPYCW_RS10870 PF00728 Glycosyl hydrolase family 20, catalytic domain SPYCW_RS10875 PF00392 Bacterial regulatory proteins, gntR family SPYCW_RS10875 PF07702 UTRA domain SPYCW_RS10880 PF01380 SIS domain SPYCW_RS10885 PF01979 Amidohydrolase family SPYCW_RS10890 PF00381 PTS HPr component phosphorylation site SPYCW_RS10890 PF02896 PEP-utilising enzyme, TIM barrel domain SPYCW_RS10890 PF00391 PEP-utilising enzyme, mobile domain SPYCW_RS10890 PF05524 PEP-utilising enzyme, N-terminal SPYCW_RS10890 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPYCW_RS10895 PF02378 Phosphotransferase system, EIIC SPYCW_RS10895 PF00367 phosphotransferase system, EIIB SPYCW_RS10895 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPYCW_RS10900 PF00893 Small Multidrug Resistance protein SPYCW_RS10910 PF00892 EamA-like transporter family SPYCW_RS10920 PF00501 AMP-binding enzyme SPYCW_RS10920 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS10935 PF00266 Aminotransferase class-V SPYCW_RS10940 PF02347 Glycine cleavage system P-protein SPYCW_RS10950 PF01597 Glycine cleavage H-protein SPYCW_RS10955 PF08669 Glycine cleavage T-protein C-terminal barrel domain SPYCW_RS10955 PF01571 Aminomethyltransferase folate-binding domain SPYCW_RS10965 PF01966 HD domain SPYCW_RS10965 PF13286 Phosphohydrolase-associated domain SPYCW_RS10975 PF00091 Tubulin/FtsZ family, GTPase domain SPYCW_RS10975 PF12327 FtsZ family, C-terminal domain SPYCW_RS10980 PF02491 SHS2 domain inserted in FTSA SPYCW_RS10985 PF03799 Cell division protein FtsQ SPYCW_RS10985 PF08478 POTRA domain, FtsQ-type SPYCW_RS10990 PF01820 D-ala D-ala ligase N-terminus SPYCW_RS10990 PF07478 D-ala D-ala ligase C-terminus SPYCW_RS10995 PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain SPYCW_RS10995 PF01565 FAD binding domain SPYCW_RS11005 PF02875 Mur ligase family, glutamate ligase domain SPYCW_RS11005 PF01225 Mur ligase family, catalytic domain SPYCW_RS11005 PF08245 Mur ligase middle domain SPYCW_RS11010 PF03033 Glycosyltransferase family 28 N-terminal domain SPYCW_RS11010 PF04101 Glycosyltransferase family 28 C-terminal domain SPYCW_RS11015 PF01098 Cell cycle protein SPYCW_RS11020 PF02875 Mur ligase family, glutamate ligase domain SPYCW_RS11020 PF08245 Mur ligase middle domain SPYCW_RS11025 PF00953 Glycosyl transferase family 4 SPYCW_RS11025 PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 SPYCW_RS11030 PF08245 Mur ligase middle domain SPYCW_RS11030 PF01225 Mur ligase family, catalytic domain SPYCW_RS11030 PF02875 Mur ligase family, glutamate ligase domain SPYCW_RS11035 PF01225 Mur ligase family, catalytic domain SPYCW_RS11035 PF02875 Mur ligase family, glutamate ligase domain SPYCW_RS11035 PF08245 Mur ligase middle domain SPYCW_RS11040 PF03717 Penicillin-binding Protein dimerisation domain SPYCW_RS11040 PF00905 Penicillin binding protein transpeptidase domain SPYCW_RS11050 PF01795 MraW methylase family SPYCW_RS11055 PF02381 MraZ protein, putative antitoxin-like SPYCW_RS11070 PF00571 CBS domain SPYCW_RS11070 PF00291 Pyridoxal-phosphate dependent enzyme SPYCW_RS11075 PF00593 TonB dependent receptor SPYCW_RS11075 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS11090 PF00698 Acyl transferase domain SPYCW_RS11100 PF01225 Mur ligase family, catalytic domain SPYCW_RS11100 PF08245 Mur ligase middle domain SPYCW_RS11100 PF02875 Mur ligase family, glutamate ligase domain SPYCW_RS11110 PF01250 Ribosomal protein S6 SPYCW_RS11115 PF01084 Ribosomal protein S18 SPYCW_RS11120 PF01281 Ribosomal protein L9, N-terminal domain SPYCW_RS11120 PF03948 Ribosomal protein L9, C-terminal domain SPYCW_RS11125 PF01227 GTP cyclohydrolase I SPYCW_RS11130 PF00593 TonB dependent receptor SPYCW_RS11130 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS11150 PF03884 DNA gyrase inhibitor YacG SPYCW_RS11160 PF02545 Maf-like protein SPYCW_RS11165 PF01176 Translation initiation factor 1A / IF-1 SPYCW_RS11180 PF13537 Glutamine amidotransferase domain SPYCW_RS11180 PF00733 Asparagine synthase SPYCW_RS11205 PF01471 Putative peptidoglycan binding domain SPYCW_RS11205 PF13401 AAA domain SPYCW_RS11215 PF13614 AAA domain SPYCW_RS11230 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPYCW_RS11230 PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SPYCW_RS11235 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS11235 PF00501 AMP-binding enzyme SPYCW_RS11260 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS11265 PF08241 Methyltransferase domain SPYCW_RS11275 PF00581 Rhodanese-like domain SPYCW_RS11275 PF17773 UPF0176 acylphosphatase like domain SPYCW_RS11280 PF00732 GMC oxidoreductase SPYCW_RS11280 PF05199 GMC oxidoreductase SPYCW_RS11290 PF01274 Malate synthase SPYCW_RS11305 PF01546 Peptidase family M20/M25/M40 SPYCW_RS11305 PF07687 Peptidase dimerisation domain SPYCW_RS11310 PF04958 Arginine N-succinyltransferase beta subunit SPYCW_RS11315 PF04996 Succinylarginine dihydrolase SPYCW_RS11330 PF00561 alpha/beta hydrolase fold SPYCW_RS11335 PF00561 alpha/beta hydrolase fold SPYCW_RS11340 PF00083 Sugar (and other) transporter SPYCW_RS11340 PF08946 Osmosensory transporter coiled coil SPYCW_RS11345 PF00271 Helicase conserved C-terminal domain SPYCW_RS11345 PF00270 DEAD/DEAH box helicase SPYCW_RS11350 PF01925 Sulfite exporter TauE/SafE SPYCW_RS11355 PF00581 Rhodanese-like domain SPYCW_RS11355 PF11127 Protein of unknown function (DUF2892) SPYCW_RS11360 PF01022 Bacterial regulatory protein, arsR family SPYCW_RS11365 PF00753 Metallo-beta-lactamase superfamily SPYCW_RS11370 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPYCW_RS11370 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPYCW_RS11375 PF01197 Ribosomal protein L31 SPYCW_RS11380 PF07977 FabA-like domain SPYCW_RS11395 PF02163 Peptidase family M50 SPYCW_RS11395 PF17820 PDZ domain SPYCW_RS11400 PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain SPYCW_RS11400 PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase SPYCW_RS11400 PF13288 DXP reductoisomerase C-terminal domain SPYCW_RS11410 PF01255 Putative undecaprenyl diphosphate synthase SPYCW_RS11415 PF01765 Ribosome recycling factor SPYCW_RS11420 PF00696 Amino acid kinase family SPYCW_RS11425 PF00889 Elongation factor TS SPYCW_RS11430 PF00318 Ribosomal protein S2 SPYCW_RS11440 PF01066 CDP-alcohol phosphatidyltransferase SPYCW_RS11445 PF02666 Phosphatidylserine decarboxylase SPYCW_RS11450 PF00180 Isocitrate/isopropylmalate dehydrogenase SPYCW_RS11455 PF02254 TrkA-N domain SPYCW_RS11455 PF00999 Sodium/hydrogen exchanger family SPYCW_RS11460 PF00675 Insulinase (Peptidase family M16) SPYCW_RS11460 PF05193 Peptidase M16 inactive domain SPYCW_RS11465 PF00795 Carbon-nitrogen hydrolase SPYCW_RS11485 PF14759 Reductase C-terminal SPYCW_RS11485 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS11490 PF04397 LytTr DNA-binding domain SPYCW_RS11490 PF00072 Response regulator receiver domain SPYCW_RS11495 PF02743 Cache domain SPYCW_RS11495 PF00672 HAMP domain SPYCW_RS11495 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS11495 PF06580 Histidine kinase SPYCW_RS11515 PF00072 Response regulator receiver domain SPYCW_RS11515 PF00196 Bacterial regulatory proteins, luxR family SPYCW_RS11520 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS11520 PF01627 Hpt domain SPYCW_RS11520 PF00072 Response regulator receiver domain SPYCW_RS11520 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS11530 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS11530 PF00563 EAL domain SPYCW_RS11530 PF03707 Bacterial signalling protein N terminal repeat SPYCW_RS11530 PF13188 PAS domain SPYCW_RS11555 PF05717 IS66 Orf2 like protein SPYCW_RS11560 PF13817 IS66 C-terminal element SPYCW_RS11560 PF13007 Transposase C of IS166 homeodomain SPYCW_RS11560 PF13005 zinc-finger binding domain of transposase IS66 SPYCW_RS11560 PF03050 Transposase IS66 family SPYCW_RS11610 PF05717 IS66 Orf2 like protein SPYCW_RS11700 PF06986 Type-1V conjugative transfer system mating pair stabilisation SPYCW_RS11760 PF06122 Conjugative relaxosome accessory transposon protein SPYCW_RS11830 PF07057 DNA helicase TraI SPYCW_RS11830 PF18340 DNA relaxase TraI 2B/2B-like domain SPYCW_RS11830 PF08751 TrwC relaxase SPYCW_RS11830 PF18272 single-stranded DNA binding TraI N-terminal subdomain SPYCW_RS11835 PF12615 F sex factor protein N terminal SPYCW_RS11835 PF10412 Type IV secretion-system coupling protein DNA-binding domain SPYCW_RS11895 PF05443 ROS/MUCR transcriptional regulator protein SPYCW_RS11975 PF03466 LysR substrate binding domain SPYCW_RS11975 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS11995 PF02384 N-6 DNA Methylase SPYCW_RS12050 PF02661 Fic/DOC family SPYCW_RS12050 PF17841 BID domain of Bartonella effector protein (Bep) SPYCW_RS12060 PF00589 Phage integrase family SPYCW_RS12060 PF13356 Arm DNA-binding domain SPYCW_RS12075 PF02673 Bacitracin resistance protein BacA SPYCW_RS12080 PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster SPYCW_RS12080 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS12090 PF04898 Glutamate synthase central domain SPYCW_RS12090 PF01493 GXGXG motif SPYCW_RS12090 PF00310 Glutamine amidotransferases class-II SPYCW_RS12090 PF01645 Conserved region in glutamate synthase SPYCW_RS12100 PF13417 Glutathione S-transferase, N-terminal domain SPYCW_RS12100 PF00043 Glutathione S-transferase, C-terminal domain SPYCW_RS12115 PF00696 Amino acid kinase family SPYCW_RS12115 PF01842 ACT domain SPYCW_RS12115 PF13840 ACT domain SPYCW_RS12130 PF00141 Peroxidase SPYCW_RS12135 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS12145 PF03060 Nitronate monooxygenase SPYCW_RS12155 PF05524 PEP-utilising enzyme, N-terminal SPYCW_RS12155 PF00391 PEP-utilising enzyme, mobile domain SPYCW_RS12155 PF02896 PEP-utilising enzyme, TIM barrel domain SPYCW_RS12165 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS12165 PF12002 MgsA AAA+ ATPase C terminal SPYCW_RS12165 PF16193 AAA C-terminal domain SPYCW_RS12170 PF00534 Glycosyl transferases group 1 SPYCW_RS12170 PF08323 Starch synthase catalytic domain SPYCW_RS12175 PF00571 CBS domain SPYCW_RS12175 PF03471 Transporter associated domain SPYCW_RS12180 PF02130 Uncharacterized protein family UPF0054 SPYCW_RS12190 PF04542 Sigma-70 region 2 SPYCW_RS12190 PF08281 Sigma-70, region 4 SPYCW_RS12195 PF02627 Carboxymuconolactone decarboxylase family SPYCW_RS12205 PF02562 PhoH-like protein SPYCW_RS12210 PF04055 Radical SAM superfamily SPYCW_RS12210 PF01938 TRAM domain SPYCW_RS12210 PF00919 Uncharacterized protein family UPF0004 SPYCW_RS12220 PF01475 Ferric uptake regulator family SPYCW_RS12225 PF05443 ROS/MUCR transcriptional regulator protein SPYCW_RS12230 PF00814 Glycoprotease family SPYCW_RS12230 PF00583 Acetyltransferase (GNAT) family SPYCW_RS12235 PF00814 Glycoprotease family SPYCW_RS12240 PF00881 Nitroreductase family SPYCW_RS12245 PF01106 NifU-like domain SPYCW_RS12265 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SPYCW_RS12265 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SPYCW_RS12270 PF03450 CO dehydrogenase flavoprotein C-terminal domain SPYCW_RS12270 PF00941 FAD binding domain in molybdopterin dehydrogenase SPYCW_RS12275 PF00111 2Fe-2S iron-sulfur cluster binding domain SPYCW_RS12275 PF01799 [2Fe-2S] binding domain SPYCW_RS12275 PF10518 TAT (twin-arginine translocation) pathway signal sequence SPYCW_RS12285 PF09278 MerR, DNA binding SPYCW_RS12285 PF00376 MerR family regulatory protein SPYCW_RS12295 PF01741 Large-conductance mechanosensitive channel, MscL SPYCW_RS12325 PF01272 Transcription elongation factor, GreA/GreB, C-term SPYCW_RS12325 PF03449 Transcription elongation factor, N-terminal SPYCW_RS12330 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPYCW_RS12330 PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SPYCW_RS12330 PF02142 MGS-like domain SPYCW_RS12340 PF00117 Glutamine amidotransferase class-I SPYCW_RS12340 PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain SPYCW_RS12350 PF04480 Protein of unknown function (DUF559) SPYCW_RS12355 PF08278 DNA primase DnaG DnaB-binding SPYCW_RS12355 PF10410 DnaB-helicase binding domain of primase SPYCW_RS12355 PF08275 DNA primase catalytic core, N-terminal domain SPYCW_RS12355 PF01807 CHC2 zinc finger SPYCW_RS12360 PF04542 Sigma-70 region 2 SPYCW_RS12360 PF04539 Sigma-70 region 3 SPYCW_RS12360 PF04545 Sigma-70, region 4 SPYCW_RS12360 PF00140 Sigma-70 factor, region 1.2 SPYCW_RS12360 PF03979 Sigma-70 factor, region 1.1 SPYCW_RS12360 PF04546 Sigma-70, non-essential region SPYCW_RS12375 PF07724 AAA domain (Cdc48 subfamily) SPYCW_RS12375 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS12375 PF10431 C-terminal, D2-small domain, of ClpB protein SPYCW_RS12375 PF02861 Clp amino terminal domain, pathogenicity island component SPYCW_RS12375 PF17871 AAA lid domain SPYCW_RS12385 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPYCW_RS12410 PF05675 Protein of unknown function (DUF817) SPYCW_RS12415 PF01321 Creatinase/Prolidase N-terminal domain SPYCW_RS12415 PF00557 Metallopeptidase family M24 SPYCW_RS12420 PF07075 Protein of unknown function (DUF1343) SPYCW_RS12430 PF01479 S4 domain SPYCW_RS12430 PF00579 tRNA synthetases class I (W and Y) SPYCW_RS12440 PF17191 RecG wedge domain SPYCW_RS12440 PF00271 Helicase conserved C-terminal domain SPYCW_RS12440 PF00270 DEAD/DEAH box helicase SPYCW_RS12450 PF00270 DEAD/DEAH box helicase SPYCW_RS12450 PF02559 CarD-like/TRCF domain SPYCW_RS12450 PF17757 UvrB interaction domain SPYCW_RS12450 PF03461 TRCF domain SPYCW_RS12450 PF00271 Helicase conserved C-terminal domain SPYCW_RS12455 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS12455 PF00563 EAL domain SPYCW_RS12455 PF13185 GAF domain SPYCW_RS12460 PF06463 Molybdenum Cofactor Synthesis C SPYCW_RS12460 PF04055 Radical SAM superfamily SPYCW_RS12465 PF01513 ATP-NAD kinase SPYCW_RS12475 PF13356 Arm DNA-binding domain SPYCW_RS12475 PF00589 Phage integrase family SPYCW_RS12485 PF12728 Helix-turn-helix domain SPYCW_RS12500 PF02384 N-6 DNA Methylase SPYCW_RS12505 PF01420 Type I restriction modification DNA specificity domain SPYCW_RS12510 PF18766 SWI2/SNF2 ATPase SPYCW_RS12510 PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) SPYCW_RS12510 PF11867 Domain of unknown function (DUF3387) SPYCW_RS12530 PF04002 RadC-like JAB domain SPYCW_RS12540 PF00682 HMGL-like SPYCW_RS12540 PF07836 DmpG-like communication domain SPYCW_RS12545 PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation SPYCW_RS12545 PF01118 Semialdehyde dehydrogenase, NAD binding domain SPYCW_RS12550 PF01557 Fumarylacetoacetate (FAA) hydrolase family SPYCW_RS12555 PF06052 3-hydroxyanthranilic acid dioxygenase SPYCW_RS12560 PF01042 Endoribonuclease L-PSP SPYCW_RS12565 PF01557 Fumarylacetoacetate (FAA) hydrolase family SPYCW_RS12570 PF00171 Aldehyde dehydrogenase family SPYCW_RS12580 PF00005 ABC transporter SPYCW_RS12585 PF00528 Binding-protein-dependent transport system inner membrane component SPYCW_RS12590 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPYCW_RS12600 PF01557 Fumarylacetoacetate (FAA) hydrolase family SPYCW_RS12605 PF01925 Sulfite exporter TauE/SafE SPYCW_RS12610 PF03447 Homoserine dehydrogenase, NAD binding domain SPYCW_RS12610 PF01958 Domain of unknown function DUF108 SPYCW_RS12625 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS12625 PF03466 LysR substrate binding domain SPYCW_RS12630 PF00324 Amino acid permease SPYCW_RS12635 PF00266 Aminotransferase class-V SPYCW_RS12640 PF00171 Aldehyde dehydrogenase family SPYCW_RS12645 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPYCW_RS12645 PF00205 Thiamine pyrophosphate enzyme, central domain SPYCW_RS12645 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPYCW_RS12650 PF01557 Fumarylacetoacetate (FAA) hydrolase family SPYCW_RS12665 PF00593 TonB dependent receptor SPYCW_RS12665 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS12670 PF00561 alpha/beta hydrolase fold SPYCW_RS12675 PF00196 Bacterial regulatory proteins, luxR family SPYCW_RS12675 PF03472 Autoinducer binding domain SPYCW_RS12680 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS12680 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS12680 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS12695 PF00593 TonB dependent receptor SPYCW_RS12695 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS12700 PF03472 Autoinducer binding domain SPYCW_RS12700 PF00196 Bacterial regulatory proteins, luxR family SPYCW_RS12705 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS12705 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS12705 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS12710 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS12710 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS12710 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS12725 PF07883 Cupin domain SPYCW_RS12725 PF01381 Helix-turn-helix SPYCW_RS12730 PF00593 TonB dependent receptor SPYCW_RS12730 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS12735 PF01979 Amidohydrolase family SPYCW_RS12740 PF00171 Aldehyde dehydrogenase family SPYCW_RS12750 PF02705 K+ potassium transporter SPYCW_RS12755 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS12755 PF00072 Response regulator receiver domain SPYCW_RS12770 PF00462 Glutaredoxin SPYCW_RS12785 PF00293 NUDIX domain SPYCW_RS12805 PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SPYCW_RS12810 PF02899 Phage integrase, N-terminal SAM-like domain SPYCW_RS12810 PF00589 Phage integrase family SPYCW_RS12820 PF01202 Shikimate kinase SPYCW_RS12825 PF01761 3-dehydroquinate synthase SPYCW_RS12830 PF00999 Sodium/hydrogen exchanger family SPYCW_RS12830 PF02254 TrkA-N domain SPYCW_RS12845 PF06745 KaiC SPYCW_RS12845 PF18073 Rubredoxin metal binding domain SPYCW_RS12850 PF00923 Transaldolase/Fructose-6-phosphate aldolase SPYCW_RS12855 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS12865 PF00171 Aldehyde dehydrogenase family SPYCW_RS12870 PF16177 Acetyl-coenzyme A synthetase N-terminus SPYCW_RS12870 PF00501 AMP-binding enzyme SPYCW_RS12870 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS12875 PF00144 Beta-lactamase SPYCW_RS12895 PF14403 Circularly permuted ATP-grasp type 2 SPYCW_RS12905 PF02810 SEC-C motif SPYCW_RS12905 PF07516 SecA Wing and Scaffold domain SPYCW_RS12905 PF01043 SecA preprotein cross-linking domain SPYCW_RS12905 PF07517 SecA DEAD-like domain SPYCW_RS12960 PF05114 Protein of unknown function (DUF692) SPYCW_RS12970 PF01272 Transcription elongation factor, GreA/GreB, C-term SPYCW_RS12970 PF03449 Transcription elongation factor, N-terminal SPYCW_RS12985 PF00270 DEAD/DEAH box helicase SPYCW_RS12985 PF00271 Helicase conserved C-terminal domain SPYCW_RS12990 PF00107 Zinc-binding dehydrogenase SPYCW_RS12990 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS12995 PF00756 Putative esterase SPYCW_RS13010 PF00551 Formyl transferase SPYCW_RS13015 PF00107 Zinc-binding dehydrogenase SPYCW_RS13015 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS13025 PF03315 Serine dehydratase beta chain SPYCW_RS13025 PF03313 Serine dehydratase alpha chain SPYCW_RS13030 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain SPYCW_RS13030 PF02777 Iron/manganese superoxide dismutases, C-terminal domain SPYCW_RS13040 PF01068 ATP dependent DNA ligase domain SPYCW_RS13040 PF04675 DNA ligase N terminus SPYCW_RS13040 PF04679 ATP dependent DNA ligase C terminal region SPYCW_RS13055 PF13426 PAS domain SPYCW_RS13055 PF07536 HWE histidine kinase SPYCW_RS13055 PF08447 PAS fold SPYCW_RS13060 PF00072 Response regulator receiver domain SPYCW_RS13065 PF08281 Sigma-70, region 4 SPYCW_RS13065 PF04542 Sigma-70 region 2 SPYCW_RS13080 PF08281 Sigma-70, region 4 SPYCW_RS13080 PF04542 Sigma-70 region 2 SPYCW_RS13085 PF07995 Glucose / Sorbosone dehydrogenase SPYCW_RS13090 PF12697 Alpha/beta hydrolase family SPYCW_RS13095 PF13302 Acetyltransferase (GNAT) domain SPYCW_RS13130 PF13291 ACT domain SPYCW_RS13130 PF00291 Pyridoxal-phosphate dependent enzyme SPYCW_RS13135 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase SPYCW_RS13135 PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SPYCW_RS13140 PF07969 Amidohydrolase family SPYCW_RS13145 PF01266 FAD dependent oxidoreductase SPYCW_RS13150 PF01070 FMN-dependent dehydrogenase SPYCW_RS13165 PF04551 GcpE protein SPYCW_RS13170 PF00561 alpha/beta hydrolase fold SPYCW_RS13175 PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA SPYCW_RS13180 PF01483 Proprotein convertase P-domain SPYCW_RS13180 PF04389 Peptidase family M28 SPYCW_RS13190 PF00575 S1 RNA binding domain SPYCW_RS13190 PF03725 3' exoribonuclease family, domain 2 SPYCW_RS13190 PF01138 3' exoribonuclease family, domain 1 SPYCW_RS13190 PF00013 KH domain SPYCW_RS13190 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain SPYCW_RS13195 PF00312 Ribosomal protein S15 SPYCW_RS13200 PF01509 TruB family pseudouridylate synthase (N terminal domain) SPYCW_RS13200 PF16198 tRNA pseudouridylate synthase B C-terminal domain SPYCW_RS13215 PF00265 Thymidine kinase SPYCW_RS13220 PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain SPYCW_RS13220 PF06974 Protein of unknown function (DUF1298) SPYCW_RS13250 PF01039 Carboxyl transferase domain SPYCW_RS13265 PF00892 EamA-like transporter family SPYCW_RS13270 PF03481 Putative GTP-binding controlling metal-binding SPYCW_RS13270 PF01300 Telomere recombination SPYCW_RS13275 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS13275 PF12806 Acetyl-CoA dehydrogenase C-terminal like SPYCW_RS13275 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS13275 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS13280 PF03707 Bacterial signalling protein N terminal repeat SPYCW_RS13280 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS13280 PF00563 EAL domain SPYCW_RS13285 PF03477 ATP cone domain SPYCW_RS13285 PF02867 Ribonucleotide reductase, barrel domain SPYCW_RS13285 PF00317 Ribonucleotide reductase, all-alpha domain SPYCW_RS13295 PF00268 Ribonucleotide reductase, small chain SPYCW_RS13380 PF00009 Elongation factor Tu GTP binding domain SPYCW_RS13380 PF00679 Elongation factor G C-terminus SPYCW_RS13380 PF06421 GTP-binding protein LepA C-terminus SPYCW_RS13380 PF03144 Elongation factor Tu domain 2 SPYCW_RS13415 PF10414 Sirohaem synthase dimerisation region SPYCW_RS13415 PF14824 Sirohaem biosynthesis protein central SPYCW_RS13415 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SPYCW_RS13420 PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SPYCW_RS13420 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPYCW_RS13430 PF14698 Argininosuccinate lyase C-terminal SPYCW_RS13430 PF00206 Lyase SPYCW_RS13435 PF08534 Redoxin SPYCW_RS13445 PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SPYCW_RS13445 PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPYCW_RS13450 PF00561 alpha/beta hydrolase fold SPYCW_RS13455 PF12146 Serine aminopeptidase, S33 SPYCW_RS13465 PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain SPYCW_RS13465 PF06974 Protein of unknown function (DUF1298) SPYCW_RS13470 PF01553 Acyltransferase SPYCW_RS13475 PF01553 Acyltransferase SPYCW_RS13480 PF01081 KDPG and KHG aldolase SPYCW_RS13485 PF00920 Dehydratase family SPYCW_RS13490 PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain SPYCW_RS13490 PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain SPYCW_RS13500 PF01266 FAD dependent oxidoreductase SPYCW_RS13500 PF16901 C-terminal domain of alpha-glycerophosphate oxidase SPYCW_RS13505 PF00106 short chain dehydrogenase SPYCW_RS13510 PF12833 Helix-turn-helix domain SPYCW_RS13510 PF12852 Cupin SPYCW_RS13515 PF03475 3-alpha domain SPYCW_RS13515 PF03473 MOSC domain SPYCW_RS13530 PF02634 FdhD/NarQ family SPYCW_RS13535 PF12804 MobA-like NTP transferase domain SPYCW_RS13540 PF00384 Molybdopterin oxidoreductase SPYCW_RS13545 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS13545 PF08521 Two-component sensor kinase N-terminal SPYCW_RS13545 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS13550 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS13550 PF00072 Response regulator receiver domain SPYCW_RS13565 PF13378 Enolase C-terminal domain-like SPYCW_RS13565 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SPYCW_RS13580 PF00005 ABC transporter SPYCW_RS13580 PF00664 ABC transporter transmembrane region SPYCW_RS13590 PF02472 Biopolymer transport protein ExbD/TolR SPYCW_RS13595 PF00691 OmpA family SPYCW_RS13620 PF02033 Ribosome-binding factor A SPYCW_RS13630 PF08364 Bacterial translation initiation factor IF-2 associated region SPYCW_RS13630 PF11987 Translation-initiation factor 2 SPYCW_RS13630 PF00009 Elongation factor Tu GTP binding domain SPYCW_RS13630 PF04760 Translation initiation factor IF-2, N-terminal region SPYCW_RS13640 PF00575 S1 RNA binding domain SPYCW_RS13640 PF08529 NusA N-terminal domain SPYCW_RS13640 PF13184 NusA-like KH domain SPYCW_RS13645 PF02576 RimP N-terminal domain SPYCW_RS13645 PF17384 RimP C-terminal SH3 domain SPYCW_RS13650 PF00313 'Cold-shock' DNA-binding domain SPYCW_RS13685 PF01925 Sulfite exporter TauE/SafE SPYCW_RS13700 PF06965 Na+/H+ antiporter 1 SPYCW_RS13710 PF03301 Tryptophan 2,3-dioxygenase SPYCW_RS13715 PF00698 Acyl transferase domain SPYCW_RS13715 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS13715 PF00107 Zinc-binding dehydrogenase SPYCW_RS13715 PF00109 Beta-ketoacyl synthase, N-terminal domain SPYCW_RS13715 PF02801 Beta-ketoacyl synthase, C-terminal domain SPYCW_RS13715 PF08659 KR domain SPYCW_RS13715 PF00550 Phosphopantetheine attachment site SPYCW_RS13715 PF14765 Polyketide synthase dehydratase SPYCW_RS13715 PF16197 Ketoacyl-synthetase C-terminal extension SPYCW_RS13720 PF07969 Amidohydrolase family SPYCW_RS13730 PF08274 PhnA Zinc-Ribbon SPYCW_RS13730 PF03831 PhnA domain SPYCW_RS13735 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS13735 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS13735 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS13750 PF01012 Electron transfer flavoprotein domain SPYCW_RS13750 PF00766 Electron transfer flavoprotein FAD-binding domain SPYCW_RS13755 PF01012 Electron transfer flavoprotein domain SPYCW_RS13760 PF00549 CoA-ligase SPYCW_RS13760 PF08442 ATP-grasp domain SPYCW_RS13775 PF01625 Peptide methionine sulfoxide reductase SPYCW_RS13780 PF00155 Aminotransferase class I and II SPYCW_RS13785 PF00425 chorismate binding enzyme SPYCW_RS13785 PF04715 Anthranilate synthase component I, N terminal region SPYCW_RS13795 PF00501 AMP-binding enzyme SPYCW_RS13795 PF13193 AMP-binding enzyme C-terminal domain SPYCW_RS13820 PF05683 Fumarase C-terminus SPYCW_RS13820 PF05681 Fumarate hydratase (Fumerase) SPYCW_RS13855 PF02622 Uncharacterized ACR, COG1678 SPYCW_RS13860 PF00462 Glutaredoxin SPYCW_RS13860 PF08534 Redoxin SPYCW_RS13865 PF10423 Bacterial AMP nucleoside phosphorylase N-terminus SPYCW_RS13865 PF01048 Phosphorylase superfamily SPYCW_RS13905 PF12802 MarR family SPYCW_RS13910 PF00529 HlyD membrane-fusion protein of T1SS SPYCW_RS13910 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPYCW_RS13915 PF07690 Major Facilitator Superfamily SPYCW_RS13945 PF02774 Semialdehyde dehydrogenase, dimerisation domain SPYCW_RS13945 PF01118 Semialdehyde dehydrogenase, NAD binding domain SPYCW_RS13950 PF06940 Domain of unknown function (DUF1287) SPYCW_RS13955 PF01245 Ribosomal protein L19 SPYCW_RS13960 PF01746 tRNA (Guanine-1)-methyltransferase SPYCW_RS13975 PF03466 LysR substrate binding domain SPYCW_RS13975 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS13985 PF05230 MASE2 domain SPYCW_RS13985 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS13990 PF00144 Beta-lactamase SPYCW_RS13995 PF05239 PRC-barrel domain SPYCW_RS13995 PF01782 RimM N-terminal domain SPYCW_RS14000 PF00886 Ribosomal protein S16 SPYCW_RS14005 PF02978 Signal peptide binding domain SPYCW_RS14005 PF02881 SRP54-type protein, helical bundle domain SPYCW_RS14005 PF00448 SRP54-type protein, GTPase domain SPYCW_RS14010 PF13188 PAS domain SPYCW_RS14010 PF03707 Bacterial signalling protein N terminal repeat SPYCW_RS14010 PF00563 EAL domain SPYCW_RS14010 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS14020 PF01678 Diaminopimelate epimerase SPYCW_RS14025 PF04055 Radical SAM superfamily SPYCW_RS14025 PF00919 Uncharacterized protein family UPF0004 SPYCW_RS14030 PF00448 SRP54-type protein, GTPase domain SPYCW_RS14030 PF02881 SRP54-type protein, helical bundle domain SPYCW_RS14035 PF04279 Intracellular septation protein A SPYCW_RS14045 PF00132 Bacterial transferase hexapeptide (six repeats) SPYCW_RS14060 PF00490 Delta-aminolevulinic acid dehydratase SPYCW_RS14065 PF04225 Opacity-associated protein A LysM-like domain SPYCW_RS14065 PF01551 Peptidase family M23 SPYCW_RS14070 PF00270 DEAD/DEAH box helicase SPYCW_RS14070 PF17191 RecG wedge domain SPYCW_RS14070 PF00271 Helicase conserved C-terminal domain SPYCW_RS14075 PF01479 S4 domain SPYCW_RS14075 PF00163 Ribosomal protein S4/S9 N-terminal domain SPYCW_RS14080 PF11953 Domain of unknown function (DUF3470) SPYCW_RS14080 PF00037 4Fe-4S binding domain SPYCW_RS14085 PF00574 Clp protease SPYCW_RS14090 PF06689 ClpX C4-type zinc finger SPYCW_RS14090 PF07724 AAA domain (Cdc48 subfamily) SPYCW_RS14090 PF10431 C-terminal, D2-small domain, of ClpB protein SPYCW_RS14100 PF02657 Fe-S metabolism associated domain SPYCW_RS14140 PF04012 PspA/IM30 family SPYCW_RS14145 PF00158 Sigma-54 interaction domain SPYCW_RS14145 PF02954 Bacterial regulatory protein, Fis family SPYCW_RS14150 PF01047 MarR family SPYCW_RS14170 PF00829 Ribosomal prokaryotic L21 protein SPYCW_RS14175 PF01016 Ribosomal L27 protein SPYCW_RS14210 PF01293 Phosphoenolpyruvate carboxykinase SPYCW_RS14215 PF00486 Transcriptional regulatory protein, C terminal SPYCW_RS14215 PF00072 Response regulator receiver domain SPYCW_RS14220 PF13756 Stimulus-sensing domain SPYCW_RS14220 PF13755 Sensor N-terminal transmembrane domain SPYCW_RS14220 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS14220 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS14220 PF00672 HAMP domain SPYCW_RS14225 PF02603 HPr Serine kinase N terminus SPYCW_RS14225 PF07475 HPr Serine kinase C-terminal domain SPYCW_RS14230 PF03668 P-loop ATPase protein family SPYCW_RS14235 PF03610 PTS system fructose IIA component SPYCW_RS14235 PF03830 PTS system sorbose subfamily IIB component SPYCW_RS14240 PF00381 PTS HPr component phosphorylation site SPYCW_RS14245 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPYCW_RS14245 PF00588 SpoU rRNA Methylase family SPYCW_RS14255 PF02646 RmuC family SPYCW_RS14280 PF00012 Hsp70 protein SPYCW_RS14285 PF01556 DnaJ C terminal domain SPYCW_RS14285 PF00684 DnaJ central domain SPYCW_RS14285 PF00226 DnaJ domain SPYCW_RS14290 PF01734 Patatin-like phospholipase SPYCW_RS14290 PF11856 Protein of unknown function (DUF3376) SPYCW_RS14305 PF18074 Primosomal protein N C-terminal domain SPYCW_RS14305 PF18319 PriA DNA helicase Cys-rich region (CRR) domain SPYCW_RS14305 PF00270 DEAD/DEAH box helicase SPYCW_RS14305 PF17764 3′ DNA-binding domain (3′BD) SPYCW_RS14335 PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain SPYCW_RS14335 PF02805 Metal binding domain of Ada SPYCW_RS14335 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain SPYCW_RS14335 PF12833 Helix-turn-helix domain SPYCW_RS14355 PF01738 Dienelactone hydrolase family SPYCW_RS14360 PF00213 ATP synthase delta (OSCP) subunit SPYCW_RS14365 PF00306 ATP synthase alpha/beta chain, C terminal domain SPYCW_RS14365 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPYCW_RS14365 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPYCW_RS14370 PF00231 ATP synthase SPYCW_RS14375 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPYCW_RS14375 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPYCW_RS14380 PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain SPYCW_RS14390 PF00437 Type II/IV secretion system protein SPYCW_RS14405 PF03588 Leucyl/phenylalanyl-tRNA protein transferase SPYCW_RS14430 PF00501 AMP-binding enzyme SPYCW_RS14435 PF08448 PAS fold SPYCW_RS14435 PF00563 EAL domain SPYCW_RS14435 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS14435 PF08447 PAS fold SPYCW_RS14450 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS14450 PF00593 TonB dependent receptor SPYCW_RS14470 PF00849 RNA pseudouridylate synthase SPYCW_RS14475 PF00679 Elongation factor G C-terminus SPYCW_RS14475 PF00009 Elongation factor Tu GTP binding domain SPYCW_RS14475 PF03144 Elongation factor Tu domain 2 SPYCW_RS14485 PF01654 Cytochrome bd terminal oxidase subunit I SPYCW_RS14490 PF02322 Cytochrome bd terminal oxidase subunit II SPYCW_RS14500 PF01048 Phosphorylase superfamily SPYCW_RS14525 PF07290 Protein of unknown function (DUF1449) SPYCW_RS14530 PF01145 SPFH domain / Band 7 family SPYCW_RS14530 PF15975 Flotillin SPYCW_RS14540 PF04542 Sigma-70 region 2 SPYCW_RS14540 PF08281 Sigma-70, region 4 SPYCW_RS14555 PF02311 AraC-like ligand binding domain SPYCW_RS14555 PF12833 Helix-turn-helix domain SPYCW_RS14565 PF13229 Right handed beta helix region SPYCW_RS14565 PF12708 Pectate lyase superfamily protein SPYCW_RS14565 PF00353 RTX calcium-binding nonapeptide repeat (4 copies) SPYCW_RS14570 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS14585 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS14585 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS14585 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS14595 PF03551 Transcriptional regulator PadR-like family SPYCW_RS14605 PF07687 Peptidase dimerisation domain SPYCW_RS14605 PF01546 Peptidase family M20/M25/M40 SPYCW_RS14620 PF02910 Fumarate reductase flavoprotein C-term SPYCW_RS14620 PF00890 FAD binding domain SPYCW_RS14645 PF01523 Putative modulator of DNA gyrase SPYCW_RS14680 PF00543 Nitrogen regulatory protein P-II SPYCW_RS14685 PF00909 Ammonium Transporter Family SPYCW_RS14690 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS14690 PF00593 TonB dependent receptor SPYCW_RS14710 PF05199 GMC oxidoreductase SPYCW_RS14710 PF00732 GMC oxidoreductase SPYCW_RS14715 PF04116 Fatty acid hydroxylase superfamily SPYCW_RS14745 PF00271 Helicase conserved C-terminal domain SPYCW_RS14745 PF00570 HRDC domain SPYCW_RS14745 PF09382 RQC domain SPYCW_RS14745 PF16124 RecQ zinc-binding SPYCW_RS14745 PF00270 DEAD/DEAH box helicase SPYCW_RS14750 PF00999 Sodium/hydrogen exchanger family SPYCW_RS14750 PF02254 TrkA-N domain SPYCW_RS14755 PF00230 Major intrinsic protein SPYCW_RS14775 PF00005 ABC transporter SPYCW_RS14775 PF00664 ABC transporter transmembrane region SPYCW_RS14795 PF00313 'Cold-shock' DNA-binding domain SPYCW_RS14800 PF00210 Ferritin-like domain SPYCW_RS14815 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS14815 PF03707 Bacterial signalling protein N terminal repeat SPYCW_RS14815 PF00563 EAL domain SPYCW_RS14820 PF00731 AIR carboxylase SPYCW_RS14825 PF02222 ATP-grasp domain SPYCW_RS14825 PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain SPYCW_RS14830 PF00186 Dihydrofolate reductase SPYCW_RS14835 PF01244 Membrane dipeptidase (Peptidase family M19) SPYCW_RS14840 PF01687 Riboflavin kinase SPYCW_RS14840 PF06574 FAD synthetase SPYCW_RS14850 PF00133 tRNA synthetases class I (I, L, M and V) SPYCW_RS14850 PF08264 Anticodon-binding domain of tRNA SPYCW_RS14855 PF01252 Signal peptidase (SPase) II SPYCW_RS14865 PF01638 HxlR-like helix-turn-helix SPYCW_RS14880 PF13292 1-deoxy-D-xylulose-5-phosphate synthase SPYCW_RS14880 PF02779 Transketolase, pyrimidine binding domain SPYCW_RS14880 PF02780 Transketolase, C-terminal domain SPYCW_RS14900 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS14900 PF03466 LysR substrate binding domain SPYCW_RS14915 PF01361 Tautomerase enzyme SPYCW_RS14930 PF13280 WYL domain SPYCW_RS14930 PF08279 HTH domain SPYCW_RS14970 PF01964 Radical SAM ThiC family SPYCW_RS14970 PF13667 ThiC-associated domain SPYCW_RS14975 PF02463 RecF/RecN/SMC N terminal domain SPYCW_RS14995 PF00797 N-acetyltransferase SPYCW_RS15010 PF02566 OsmC-like protein SPYCW_RS15020 PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 SPYCW_RS15030 PF03167 Uracil DNA glycosylase superfamily SPYCW_RS15035 PF00593 TonB dependent receptor SPYCW_RS15035 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS15040 PF01503 Phosphoribosyl-ATP pyrophosphohydrolase SPYCW_RS15045 PF01230 HIT domain SPYCW_RS15050 PF01835 MG2 domain SPYCW_RS15050 PF17973 Bacterial Alpha-2-macroglobulin MG10 domain SPYCW_RS15050 PF00207 Alpha-2-macroglobulin family SPYCW_RS15050 PF07703 Alpha-2-macroglobulin bait region domain SPYCW_RS15055 PF00912 Transglycosylase SPYCW_RS15055 PF00905 Penicillin binding protein transpeptidase domain SPYCW_RS15060 PF13520 Amino acid permease SPYCW_RS15065 PF07690 Major Facilitator Superfamily SPYCW_RS15075 PF05193 Peptidase M16 inactive domain SPYCW_RS15075 PF00675 Insulinase (Peptidase family M16) SPYCW_RS15085 PF00883 Cytosol aminopeptidase family, catalytic domain SPYCW_RS15085 PF02789 Cytosol aminopeptidase family, N-terminal domain SPYCW_RS15090 PF07724 AAA domain (Cdc48 subfamily) SPYCW_RS15090 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS15090 PF02861 Clp amino terminal domain, pathogenicity island component SPYCW_RS15090 PF10431 C-terminal, D2-small domain, of ClpB protein SPYCW_RS15090 PF17871 AAA lid domain SPYCW_RS15110 PF00593 TonB dependent receptor SPYCW_RS15110 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS15115 PF01551 Peptidase family M23 SPYCW_RS15115 PF08460 Bacterial SH3 domain SPYCW_RS15125 PF13742 OB-fold nucleic acid binding domain SPYCW_RS15125 PF02601 Exonuclease VII, large subunit SPYCW_RS15130 PF02844 Phosphoribosylglycinamide synthetase, N domain SPYCW_RS15130 PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SPYCW_RS15130 PF02843 Phosphoribosylglycinamide synthetase, C domain SPYCW_RS15135 PF00829 Ribosomal prokaryotic L21 protein SPYCW_RS15145 PF00571 CBS domain SPYCW_RS15145 PF03471 Transporter associated domain SPYCW_RS15145 PF01595 Cyclin M transmembrane N-terminal domain SPYCW_RS15150 PF13488 Glycine zipper SPYCW_RS15150 PF00691 OmpA family SPYCW_RS15155 PF01914 MarC family integral membrane protein SPYCW_RS15165 PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPYCW_RS15165 PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SPYCW_RS15170 PF02325 YGGT family SPYCW_RS15175 PF00696 Amino acid kinase family SPYCW_RS15185 PF07662 Na+ dependent nucleoside transporter C-terminus SPYCW_RS15185 PF07670 Nucleoside recognition SPYCW_RS15185 PF01773 Na+ dependent nucleoside transporter N-terminus SPYCW_RS15200 PF06441 Epoxide hydrolase N terminus SPYCW_RS15210 PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SPYCW_RS15210 PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SPYCW_RS15215 PF10017 Histidine-specific methyltransferase, SAM-dependent SPYCW_RS15220 PF12867 DinB superfamily SPYCW_RS15220 PF03781 Sulfatase-modifying factor enzyme 1 SPYCW_RS15225 PF01923 Cobalamin adenosyltransferase SPYCW_RS15235 PF00749 tRNA synthetases class I (E and Q), catalytic domain SPYCW_RS15255 PF05221 S-adenosyl-L-homocysteine hydrolase SPYCW_RS15255 PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SPYCW_RS15260 PF13181 Tetratricopeptide repeat SPYCW_RS15270 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS15270 PF00593 TonB dependent receptor SPYCW_RS15275 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS15275 PF00512 His Kinase A (phospho-acceptor) domain SPYCW_RS15280 PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE SPYCW_RS15285 PF01636 Phosphotransferase enzyme family SPYCW_RS15290 PF12804 MobA-like NTP transferase domain SPYCW_RS15295 PF12705 PD-(D/E)XK nuclease superfamily SPYCW_RS15300 PF13361 UvrD-like helicase C-terminal domain SPYCW_RS15300 PF00580 UvrD/REP helicase N-terminal domain SPYCW_RS15300 PF12705 PD-(D/E)XK nuclease superfamily SPYCW_RS15305 PF00085 Thioredoxin SPYCW_RS15310 PF13360 PQQ-like domain SPYCW_RS15310 PF13442 Cytochrome C oxidase, cbb3-type, subunit III SPYCW_RS15315 PF00543 Nitrogen regulatory protein P-II SPYCW_RS15320 PF00120 Glutamine synthetase, catalytic domain SPYCW_RS15320 PF03951 Glutamine synthetase, beta-Grasp domain SPYCW_RS15330 PF01381 Helix-turn-helix SPYCW_RS15350 PF00171 Aldehyde dehydrogenase family SPYCW_RS15355 PF01960 ArgJ family SPYCW_RS15360 PF00557 Metallopeptidase family M24 SPYCW_RS15375 PF17871 AAA lid domain SPYCW_RS15375 PF02861 Clp amino terminal domain, pathogenicity island component SPYCW_RS15375 PF10431 C-terminal, D2-small domain, of ClpB protein SPYCW_RS15375 PF07724 AAA domain (Cdc48 subfamily) SPYCW_RS15375 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS15395 PF00107 Zinc-binding dehydrogenase SPYCW_RS15395 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS15415 PF00311 Phosphoenolpyruvate carboxylase SPYCW_RS15430 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS15430 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS15430 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS15435 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS15435 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS15435 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS15450 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS15450 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS15450 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS15455 PF08240 Alcohol dehydrogenase GroES-like domain SPYCW_RS15455 PF00107 Zinc-binding dehydrogenase SPYCW_RS15475 PF00144 Beta-lactamase SPYCW_RS15480 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS15480 PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SPYCW_RS15480 PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SPYCW_RS15490 PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SPYCW_RS15490 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase SPYCW_RS15495 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS15500 PF00378 Enoyl-CoA hydratase/isomerase SPYCW_RS15505 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS15505 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS15505 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS15530 PF00171 Aldehyde dehydrogenase family SPYCW_RS15535 PF03466 LysR substrate binding domain SPYCW_RS15535 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS15540 PF08125 Mannitol dehydrogenase C-terminal domain SPYCW_RS15540 PF01232 Mannitol dehydrogenase Rossmann domain SPYCW_RS15545 PF02614 Glucuronate isomerase SPYCW_RS15550 PF07690 Major Facilitator Superfamily SPYCW_RS15560 PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus SPYCW_RS15560 PF08666 SAF domain SPYCW_RS15565 PF17851 Beta xylosidase C-terminal Concanavalin A-like domain SPYCW_RS15565 PF04616 Glycosyl hydrolases family 43 SPYCW_RS15590 PF00135 Carboxylesterase family SPYCW_RS15595 PF00294 pfkB family carbohydrate kinase SPYCW_RS15610 PF00356 Bacterial regulatory proteins, lacI family SPYCW_RS15615 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPYCW_RS15615 PF00529 HlyD membrane-fusion protein of T1SS SPYCW_RS15620 PF00873 AcrB/AcrD/AcrF family SPYCW_RS15625 PF02321 Outer membrane efflux protein SPYCW_RS15640 PF01336 OB-fold nucleic acid binding domain SPYCW_RS15640 PF14579 Helix-hairpin-helix motif SPYCW_RS15640 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPYCW_RS15640 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPYCW_RS15640 PF02811 PHP domain SPYCW_RS15645 PF00669 Bacterial flagellin N-terminal helical region SPYCW_RS15645 PF07196 Flagellin hook IN motif SPYCW_RS15645 PF00700 Bacterial flagellin C-terminal helical region SPYCW_RS15650 PF02049 Flagellar hook-basal body complex protein FliE SPYCW_RS15655 PF08345 Flagellar M-ring protein C-terminal SPYCW_RS15655 PF01514 Secretory protein of YscJ/FliF family SPYCW_RS15660 PF14841 FliG middle domain SPYCW_RS15660 PF01706 FliG C-terminal domain SPYCW_RS15660 PF14842 FliG N-terminal domain SPYCW_RS15670 PF18269 T3SS EscN ATPase C-terminal domain SPYCW_RS15670 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPYCW_RS15695 PF01052 Type III flagellar switch regulator (C-ring) FliN C-term SPYCW_RS15705 PF00813 FliP family SPYCW_RS15715 PF01313 Bacterial export proteins, family 3 SPYCW_RS15720 PF01311 Bacterial export proteins, family 1 SPYCW_RS15725 PF01312 FlhB HrpN YscU SpaS Family SPYCW_RS15730 PF07196 Flagellin hook IN motif SPYCW_RS15730 PF02465 Flagellar hook-associated protein 2 N-terminus SPYCW_RS15730 PF07195 Flagellar hook-associated protein 2 C-terminus SPYCW_RS15740 PF06490 Flagellar regulatory protein FleQ SPYCW_RS15740 PF00158 Sigma-54 interaction domain SPYCW_RS15740 PF02954 Bacterial regulatory protein, Fis family SPYCW_RS15745 PF00691 OmpA family SPYCW_RS15745 PF13677 Membrane MotB of proton-channel complex MotA/MotB SPYCW_RS15750 PF01618 MotA/TolQ/ExbB proton channel family SPYCW_RS15760 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPYCW_RS15760 PF00460 Flagella basal body rod protein SPYCW_RS15770 PF02119 Flagellar P-ring protein SPYCW_RS15775 PF02107 Flagellar L-ring protein SPYCW_RS15780 PF00460 Flagella basal body rod protein SPYCW_RS15780 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPYCW_RS15785 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPYCW_RS15785 PF00460 Flagella basal body rod protein SPYCW_RS15790 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPYCW_RS15790 PF00460 Flagella basal body rod protein SPYCW_RS15795 PF03963 Flagellar hook capping protein - N-terminal region SPYCW_RS15795 PF13860 FlgD Ig-like domain SPYCW_RS15795 PF13861 FlgD Tudor-like domain SPYCW_RS15800 PF00460 Flagella basal body rod protein SPYCW_RS15800 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPYCW_RS15830 PF00771 FHIPEP family SPYCW_RS15835 PF04542 Sigma-70 region 2 SPYCW_RS15835 PF04539 Sigma-70 region 3 SPYCW_RS15835 PF04545 Sigma-70, region 4 SPYCW_RS15860 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS15860 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS15860 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS15865 PF02803 Thiolase, C-terminal domain SPYCW_RS15865 PF00108 Thiolase, N-terminal domain SPYCW_RS15870 PF02515 CoA-transferase family III SPYCW_RS15875 PF01037 Lrp/AsnC ligand binding domain SPYCW_RS15875 PF13404 AsnC-type helix-turn-helix domain SPYCW_RS15880 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SPYCW_RS15880 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPYCW_RS15895 PF03601 Conserved hypothetical protein 698 SPYCW_RS15905 PF00005 ABC transporter SPYCW_RS15925 PF02153 Prephenate dehydrogenase SPYCW_RS15930 PF00155 Aminotransferase class I and II SPYCW_RS15935 PF00561 alpha/beta hydrolase fold SPYCW_RS15940 PF00561 alpha/beta hydrolase fold SPYCW_RS15940 PF07021 Methionine biosynthesis protein MetW SPYCW_RS15950 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS15955 PF00593 TonB dependent receptor SPYCW_RS15955 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS15960 PF02515 CoA-transferase family III SPYCW_RS15965 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SPYCW_RS15965 PF02770 Acyl-CoA dehydrogenase, middle domain SPYCW_RS15965 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SPYCW_RS15980 PF03900 Porphobilinogen deaminase, C-terminal domain SPYCW_RS15980 PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain SPYCW_RS15985 PF00814 Glycoprotease family SPYCW_RS15990 PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPYCW_RS15990 PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SPYCW_RS16005 PF00294 pfkB family carbohydrate kinase SPYCW_RS16020 PF08331 Domain of unknown function (DUF1730) SPYCW_RS16025 PF00005 ABC transporter SPYCW_RS16025 PF13732 Domain of unknown function (DUF4162) SPYCW_RS16040 PF00067 Cytochrome P450 SPYCW_RS16045 PF01641 SelR domain SPYCW_RS16090 PF02195 ParB-like nuclease domain SPYCW_RS16090 PF17762 HTH domain found in ParB protein SPYCW_RS16095 PF13614 AAA domain SPYCW_RS16100 PF02527 rRNA small subunit methyltransferase G SPYCW_RS16105 PF01134 Glucose inhibited division protein A SPYCW_RS16105 PF13932 GidA associated domain SPYCW_RS16110 PF10396 GTP-binding protein TrmE N-terminus SPYCW_RS16110 PF12631 MnmE helical domain SPYCW_RS16110 PF01926 50S ribosome-binding GTPase SPYCW_RS16120 PF01738 Dienelactone hydrolase family SPYCW_RS16135 PF03741 Integral membrane protein TerC family SPYCW_RS16140 PF03992 Antibiotic biosynthesis monooxygenase SPYCW_RS16145 PF07497 Rho termination factor, RNA-binding domain SPYCW_RS16145 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPYCW_RS16145 PF07498 Rho termination factor, N-terminal domain SPYCW_RS16150 PF03653 Uncharacterised protein family (UPF0093) SPYCW_RS16155 PF01208 Uroporphyrinogen decarboxylase (URO-D) SPYCW_RS16165 PF03618 Kinase/pyrophosphorylase SPYCW_RS16170 PF02545 Maf-like protein SPYCW_RS16175 PF18317 Shikimate 5'-dehydrogenase C-terminal domain SPYCW_RS16175 PF08501 Shikimate dehydrogenase substrate binding domain SPYCW_RS16180 PF01121 Dephospho-CoA kinase SPYCW_RS16185 PF00929 Exonuclease SPYCW_RS16190 PF02482 Sigma 54 modulation protein / S30EA ribosomal protein SPYCW_RS16190 PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus SPYCW_RS16195 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPYCW_RS16215 PF00246 Zinc carboxypeptidase SPYCW_RS16215 PF18027 Cytosolic carboxypeptidase N-terminal domain SPYCW_RS16220 PF00583 Acetyltransferase (GNAT) family SPYCW_RS16225 PF00011 Hsp20/alpha crystallin family SPYCW_RS16230 PF00300 Histidine phosphatase superfamily (branch 1) SPYCW_RS16240 PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal SPYCW_RS16240 PF14602 Hexapeptide repeat of succinyl-transferase SPYCW_RS16240 PF00132 Bacterial transferase hexapeptide (six repeats) SPYCW_RS16250 PF00082 Subtilase family SPYCW_RS16255 PF01979 Amidohydrolase family SPYCW_RS16265 PF00164 Ribosomal protein S12/S23 SPYCW_RS16270 PF00177 Ribosomal protein S7p/S5e SPYCW_RS16275 PF14492 Elongation Factor G, domain II SPYCW_RS16275 PF03144 Elongation factor Tu domain 2 SPYCW_RS16275 PF00009 Elongation factor Tu GTP binding domain SPYCW_RS16275 PF03764 Elongation factor G, domain IV SPYCW_RS16275 PF00679 Elongation factor G C-terminus SPYCW_RS16280 PF03143 Elongation factor Tu C-terminal domain SPYCW_RS16280 PF03144 Elongation factor Tu domain 2 SPYCW_RS16280 PF00009 Elongation factor Tu GTP binding domain SPYCW_RS16285 PF00338 Ribosomal protein S10p/S20e SPYCW_RS16290 PF00297 Ribosomal protein L3 SPYCW_RS16295 PF00573 Ribosomal protein L4/L1 family SPYCW_RS16300 PF00276 Ribosomal protein L23 SPYCW_RS16305 PF03947 Ribosomal Proteins L2, C-terminal domain SPYCW_RS16305 PF00181 Ribosomal Proteins L2, RNA binding domain SPYCW_RS16310 PF00203 Ribosomal protein S19 SPYCW_RS16315 PF00237 Ribosomal protein L22p/L17e SPYCW_RS16320 PF00189 Ribosomal protein S3, C-terminal domain SPYCW_RS16320 PF07650 KH domain SPYCW_RS16325 PF00252 Ribosomal protein L16p/L10e SPYCW_RS16330 PF00831 Ribosomal L29 protein SPYCW_RS16335 PF00366 Ribosomal protein S17 SPYCW_RS16340 PF00238 Ribosomal protein L14p/L23e SPYCW_RS16345 PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 SPYCW_RS16345 PF00467 KOW motif SPYCW_RS16350 PF00281 Ribosomal protein L5 SPYCW_RS16350 PF00673 ribosomal L5P family C-terminus SPYCW_RS16355 PF00253 Ribosomal protein S14p/S29e SPYCW_RS16360 PF00410 Ribosomal protein S8 SPYCW_RS16365 PF00347 Ribosomal protein L6 SPYCW_RS16370 PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SPYCW_RS16375 PF03719 Ribosomal protein S5, C-terminal domain SPYCW_RS16375 PF00333 Ribosomal protein S5, N-terminal domain SPYCW_RS16380 PF00327 Ribosomal protein L30p/L7e SPYCW_RS16390 PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SPYCW_RS16395 PF00344 SecY translocase SPYCW_RS16400 PF05191 Adenylate kinase, active site lid SPYCW_RS16425 PF03949 Malic enzyme, NAD binding domain SPYCW_RS16425 PF00390 Malic enzyme, N-terminal domain SPYCW_RS16425 PF01515 Phosphate acetyl/butaryl transferase SPYCW_RS16430 PF05190 MutS family domain IV SPYCW_RS16430 PF01624 MutS domain I SPYCW_RS16430 PF05188 MutS domain II SPYCW_RS16430 PF00488 MutS domain V SPYCW_RS16430 PF05192 MutS domain III SPYCW_RS16435 PF08335 GlnD PII-uridylyltransferase SPYCW_RS16435 PF01966 HD domain SPYCW_RS16440 PF03707 Bacterial signalling protein N terminal repeat SPYCW_RS16440 PF00990 Diguanylate cyclase, GGDEF domain SPYCW_RS16440 PF00563 EAL domain SPYCW_RS16445 PF12833 Helix-turn-helix domain SPYCW_RS16445 PF01965 DJ-1/PfpI family SPYCW_RS16455 PF03147 Ferredoxin-fold anticodon binding domain SPYCW_RS16455 PF03483 B3/4 domain SPYCW_RS16455 PF01588 Putative tRNA binding domain SPYCW_RS16455 PF03484 tRNA synthetase B5 domain SPYCW_RS16455 PF17759 Phenylalanyl tRNA synthetase beta chain CLM domain SPYCW_RS16460 PF01409 tRNA synthetases class II core domain (F) SPYCW_RS16460 PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain SPYCW_RS16470 PF00453 Ribosomal protein L20 SPYCW_RS16475 PF01632 Ribosomal protein L35 SPYCW_RS16480 PF00459 Inositol monophosphatase family SPYCW_RS16485 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPYCW_RS16485 PF14572 Phosphoribosyl synthetase-associated domain SPYCW_RS16500 PF00795 Carbon-nitrogen hydrolase SPYCW_RS16500 PF02540 NAD synthase SPYCW_RS16510 PF00749 tRNA synthetases class I (E and Q), catalytic domain SPYCW_RS16520 PF00471 Ribosomal protein L33 SPYCW_RS16525 PF01037 Lrp/AsnC ligand binding domain SPYCW_RS16530 PF00072 Response regulator receiver domain SPYCW_RS16560 PF02569 Pantoate-beta-alanine ligase SPYCW_RS16570 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPYCW_RS16570 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPYCW_RS16570 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPYCW_RS16570 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPYCW_RS16575 PF00005 ABC transporter SPYCW_RS16580 PF04552 Sigma-54, DNA binding domain SPYCW_RS16580 PF04963 Sigma-54 factor, core binding domain SPYCW_RS16580 PF00309 Sigma-54 factor, Activator interacting domain (AID) SPYCW_RS16585 PF00444 Ribosomal protein L36 SPYCW_RS16595 PF00144 Beta-lactamase SPYCW_RS16600 PF00326 Prolyl oligopeptidase family SPYCW_RS16600 PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain SPYCW_RS16605 PF00557 Metallopeptidase family M24 SPYCW_RS16605 PF01321 Creatinase/Prolidase N-terminal domain SPYCW_RS16620 PF01872 RibD C-terminal domain SPYCW_RS16620 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPYCW_RS16625 PF00677 Lumazine binding domain SPYCW_RS16635 PF00436 Single-strand binding protein family SPYCW_RS16640 PF07664 Ferrous iron transport protein B C terminus SPYCW_RS16640 PF02421 Ferrous iron transport protein B SPYCW_RS16640 PF07670 Nucleoside recognition SPYCW_RS16660 PF00724 NADH:flavin oxidoreductase / NADH oxidase family SPYCW_RS16670 PF00885 6,7-dimethyl-8-ribityllumazine synthase SPYCW_RS16675 PF00925 GTP cyclohydrolase II SPYCW_RS16675 PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase SPYCW_RS16685 PF02630 SCO1/SenC SPYCW_RS16690 PF03692 Putative zinc- or iron-chelating domain SPYCW_RS16700 PF00905 Penicillin binding protein transpeptidase domain SPYCW_RS16700 PF00912 Transglycosylase SPYCW_RS16705 PF01641 SelR domain SPYCW_RS16710 PF01494 FAD binding domain SPYCW_RS16720 PF02797 Chalcone and stilbene synthases, C-terminal domain SPYCW_RS16720 PF00195 Chalcone and stilbene synthases, N-terminal domain SPYCW_RS16735 PF01168 Alanine racemase, N-terminal domain SPYCW_RS16755 PF13603 Leucyl-tRNA synthetase, Domain 2 SPYCW_RS16755 PF00133 tRNA synthetases class I (I, L, M and V) SPYCW_RS16755 PF08264 Anticodon-binding domain of tRNA SPYCW_RS16755 PF09334 tRNA synthetases class I (M) SPYCW_RS16770 PF00593 TonB dependent receptor SPYCW_RS16770 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS16790 PF00270 DEAD/DEAH box helicase SPYCW_RS16790 PF00271 Helicase conserved C-terminal domain SPYCW_RS16790 PF08494 DEAD/H associated SPYCW_RS16810 PF04960 Glutaminase SPYCW_RS16815 PF03466 LysR substrate binding domain SPYCW_RS16815 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS16825 PF03330 Lytic transglycolase SPYCW_RS16845 PF01751 Toprim domain SPYCW_RS16845 PF00204 DNA gyrase B SPYCW_RS16845 PF00986 DNA gyrase B subunit, carboxyl terminus SPYCW_RS16845 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPYCW_RS16860 PF00881 Nitroreductase family SPYCW_RS16860 PF01996 F420-0:Gamma-glutamyl ligase SPYCW_RS16880 PF17863 AAA lid domain SPYCW_RS16880 PF07726 ATPase family associated with various cellular activities (AAA) SPYCW_RS16895 PF02779 Transketolase, pyrimidine binding domain SPYCW_RS16895 PF02780 Transketolase, C-terminal domain SPYCW_RS16905 PF00072 Response regulator receiver domain SPYCW_RS16905 PF00196 Bacterial regulatory proteins, luxR family SPYCW_RS16910 PF01040 UbiA prenyltransferase family SPYCW_RS16920 PF00892 EamA-like transporter family SPYCW_RS16925 PF01979 Amidohydrolase family SPYCW_RS16945 PF00027 Cyclic nucleotide-binding domain SPYCW_RS16945 PF13545 Crp-like helix-turn-helix domain SPYCW_RS16960 PF00005 ABC transporter SPYCW_RS17005 PF01555 DNA methylase SPYCW_RS17055 PF02272 DHHA1 domain SPYCW_RS17055 PF01368 DHH family SPYCW_RS17055 PF17768 RecJ OB domain SPYCW_RS17065 PF14863 Alkyl sulfatase dimerisation SPYCW_RS17065 PF00753 Metallo-beta-lactamase superfamily SPYCW_RS17065 PF14864 Alkyl sulfatase C-terminal SPYCW_RS17075 PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded SPYCW_RS17090 PF00742 Homoserine dehydrogenase SPYCW_RS17090 PF03447 Homoserine dehydrogenase, NAD binding domain SPYCW_RS17090 PF01842 ACT domain SPYCW_RS17105 PF01618 MotA/TolQ/ExbB proton channel family SPYCW_RS17110 PF02472 Biopolymer transport protein ExbD/TolR SPYCW_RS17115 PF02472 Biopolymer transport protein ExbD/TolR SPYCW_RS17120 PF00080 Copper/zinc superoxide dismutase (SODC) SPYCW_RS17130 PF01451 Low molecular weight phosphotyrosine protein phosphatase SPYCW_RS17140 PF01027 Inhibitor of apoptosis-promoting Bax1 SPYCW_RS17155 PF02464 Competence-damaged protein SPYCW_RS17155 PF00994 Probable molybdopterin binding domain SPYCW_RS17160 PF07690 Major Facilitator Superfamily SPYCW_RS17175 PF01037 Lrp/AsnC ligand binding domain SPYCW_RS17180 PF18327 Proline utilization A proline dehydrogenase N-terminal domain SPYCW_RS17180 PF01619 Proline dehydrogenase SPYCW_RS17180 PF00171 Aldehyde dehydrogenase family SPYCW_RS17180 PF14850 DNA-binding domain of Proline dehydrogenase SPYCW_RS17190 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SPYCW_RS17190 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPYCW_RS17215 PF13291 ACT domain SPYCW_RS17215 PF02824 TGS domain SPYCW_RS17215 PF04607 Region found in RelA / SpoT proteins SPYCW_RS17225 PF06580 Histidine kinase SPYCW_RS17225 PF07694 5TMR of 5TMR-LYT SPYCW_RS17230 PF00072 Response regulator receiver domain SPYCW_RS17230 PF04397 LytTr DNA-binding domain SPYCW_RS17235 PF00925 GTP cyclohydrolase II SPYCW_RS17250 PF09397 Ftsk gamma domain SPYCW_RS17250 PF17854 FtsK alpha domain SPYCW_RS17250 PF01580 FtsK/SpoIIIE family SPYCW_RS17250 PF13491 4TM region of DNA translocase FtsK/SpoIIIE SPYCW_RS17255 PF01494 FAD binding domain SPYCW_RS17270 PF05362 Lon protease (S16) C-terminal proteolytic domain SPYCW_RS17270 PF00004 ATPase family associated with various cellular activities (AAA) SPYCW_RS17270 PF02190 ATP-dependent protease La (LON) substrate-binding domain SPYCW_RS17275 PF00085 Thioredoxin SPYCW_RS17290 PF00873 AcrB/AcrD/AcrF family SPYCW_RS17320 PF02321 Outer membrane efflux protein SPYCW_RS17325 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPYCW_RS17330 PF00873 AcrB/AcrD/AcrF family SPYCW_RS17335 PF02641 Uncharacterized ACR, COG1993 SPYCW_RS17345 PF00403 Heavy-metal-associated domain SPYCW_RS17350 PF00873 AcrB/AcrD/AcrF family SPYCW_RS17360 PF02600 Disulfide bond formation protein DsbB SPYCW_RS17365 PF13462 Thioredoxin SPYCW_RS17365 PF06965 Na+/H+ antiporter 1 SPYCW_RS17375 PF05175 Methyltransferase small domain SPYCW_RS17375 PF01300 Telomere recombination SPYCW_RS17385 PF03239 Iron permease FTR1 family SPYCW_RS17395 PF09278 MerR, DNA binding SPYCW_RS17395 PF00376 MerR family regulatory protein SPYCW_RS17410 PF09278 MerR, DNA binding SPYCW_RS17410 PF00376 MerR family regulatory protein SPYCW_RS17420 PF00873 AcrB/AcrD/AcrF family SPYCW_RS17425 PF00529 HlyD membrane-fusion protein of T1SS SPYCW_RS17425 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPYCW_RS17450 PF00376 MerR family regulatory protein SPYCW_RS17450 PF09278 MerR, DNA binding SPYCW_RS17455 PF00593 TonB dependent receptor SPYCW_RS17455 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS17475 PF04945 YHS domain SPYCW_RS17480 PF01209 ubiE/COQ5 methyltransferase family SPYCW_RS17490 PF05425 Copper resistance protein D SPYCW_RS17510 PF04542 Sigma-70 region 2 SPYCW_RS17510 PF04545 Sigma-70, region 4 SPYCW_RS17515 PF07731 Multicopper oxidase SPYCW_RS17515 PF07732 Multicopper oxidase SPYCW_RS17515 PF00394 Multicopper oxidase SPYCW_RS17520 PF05275 Copper resistance protein B precursor (CopB) SPYCW_RS17545 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS17545 PF00593 TonB dependent receptor SPYCW_RS17550 PF03466 LysR substrate binding domain SPYCW_RS17550 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS17555 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPYCW_RS17560 PF00528 Binding-protein-dependent transport system inner membrane component SPYCW_RS17565 PF01053 Cys/Met metabolism PLP-dependent enzyme SPYCW_RS17570 PF00005 ABC transporter SPYCW_RS17575 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS17575 PF00593 TonB dependent receptor SPYCW_RS17590 PF00392 Bacterial regulatory proteins, gntR family SPYCW_RS17590 PF07702 UTRA domain SPYCW_RS17600 PF01209 ubiE/COQ5 methyltransferase family SPYCW_RS17635 PF00593 TonB dependent receptor SPYCW_RS17635 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS17655 PF00781 Diacylglycerol kinase catalytic domain SPYCW_RS17655 PF02142 MGS-like domain SPYCW_RS17690 PF00106 short chain dehydrogenase SPYCW_RS17695 PF07517 SecA DEAD-like domain SPYCW_RS17695 PF01043 SecA preprotein cross-linking domain SPYCW_RS17695 PF02810 SEC-C motif SPYCW_RS17695 PF07516 SecA Wing and Scaffold domain SPYCW_RS17720 PF00216 Bacterial DNA-binding protein SPYCW_RS17750 PF02899 Phage integrase, N-terminal SAM-like domain SPYCW_RS17750 PF00589 Phage integrase family SPYCW_RS17780 PF12833 Helix-turn-helix domain SPYCW_RS17780 PF14525 AraC-binding-like domain SPYCW_RS17795 PF05231 MASE1 SPYCW_RS17795 PF00563 EAL domain SPYCW_RS17810 PF02321 Outer membrane efflux protein SPYCW_RS17815 PF03412 Peptidase C39 family SPYCW_RS17815 PF00005 ABC transporter SPYCW_RS17815 PF00664 ABC transporter transmembrane region SPYCW_RS17845 PF07478 D-ala D-ala ligase C-terminus SPYCW_RS17845 PF01820 D-ala D-ala ligase N-terminus SPYCW_RS17860 PF01225 Mur ligase family, catalytic domain SPYCW_RS17860 PF02875 Mur ligase family, glutamate ligase domain SPYCW_RS17860 PF08245 Mur ligase middle domain SPYCW_RS17870 PF03472 Autoinducer binding domain SPYCW_RS17870 PF00196 Bacterial regulatory proteins, luxR family SPYCW_RS17885 PF07729 FCD domain SPYCW_RS17885 PF00392 Bacterial regulatory proteins, gntR family SPYCW_RS17935 PF00593 TonB dependent receptor SPYCW_RS17935 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS17940 PF00326 Prolyl oligopeptidase family SPYCW_RS17965 PF03743 Bacterial conjugation TrbI-like protein SPYCW_RS17980 PF04610 TrbL/VirB6 plasmid conjugal transfer protein SPYCW_RS17995 PF03135 CagE, TrbE, VirB family, component of type IV transporter system SPYCW_RS18010 PF00437 Type II/IV secretion system protein SPYCW_RS18015 PF02661 Fic/DOC family SPYCW_RS18025 PF02534 Type IV secretory system Conjugative DNA transfer SPYCW_RS18035 PF01464 Transglycosylase SLT domain SPYCW_RS18045 PF10502 Signal peptidase, peptidase S26 SPYCW_RS18080 PF03466 LysR substrate binding domain SPYCW_RS18080 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPYCW_RS18125 PF00216 Bacterial DNA-binding protein SPYCW_RS18170 PF02492 CobW/HypB/UreG, nucleotide-binding domain SPYCW_RS18170 PF07683 Cobalamin synthesis protein cobW C-terminal domain SPYCW_RS18195 PF01850 PIN domain SPYCW_RS18245 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPYCW_RS18245 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPYCW_RS18265 PF00376 MerR family regulatory protein SPYCW_RS18265 PF09278 MerR, DNA binding SPYCW_RS18285 PF02899 Phage integrase, N-terminal SAM-like domain SPYCW_RS18285 PF00589 Phage integrase family SPYCW_RS18290 PF08401 Domain of unknown function (DUF1738) SPYCW_RS18290 PF13362 Toprim domain SPYCW_RS18290 PF18818 Metallopeptidase superfamily domain SPYCW_RS18300 PF13676 TIR domain SPYCW_RS18330 PF13356 Arm DNA-binding domain SPYCW_RS18330 PF14659 Phage integrase, N-terminal SAM-like domain SPYCW_RS18330 PF00589 Phage integrase family SPYCW_RS18335 PF00216 Bacterial DNA-binding protein SPYCW_RS18340 PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase SPYCW_RS18345 PF07685 CobB/CobQ-like glutamine amidotransferase domain SPYCW_RS18350 PF03186 CobD/Cbib protein SPYCW_RS18355 PF00155 Aminotransferase class I and II SPYCW_RS18360 PF02654 Cobalamin-5-phosphate synthase SPYCW_RS18370 PF02277 Phosphoribosyltransferase SPYCW_RS18385 PF00593 TonB dependent receptor SPYCW_RS18385 PF07715 TonB-dependent Receptor Plug Domain SPYCW_RS18395 PF01728 FtsJ-like methyltransferase SPYCW_RS18400 PF02541 Ppx/GppA phosphatase family SPYCW_RS18415 PF00830 Ribosomal L28 family SPYCW_RS18420 PF14437 MafB19-like deaminase SPYCW_RS18425 PF02146 Sir2 family SPYCW_RS18430 PF05173 Dihydrodipicolinate reductase, C-terminus SPYCW_RS18430 PF01113 Dihydrodipicolinate reductase, N-terminus SPYCW_RS18440 PF10576 Iron-sulfur binding domain of endonuclease III SPYCW_RS18440 PF00633 Helix-hairpin-helix motif SPYCW_RS18440 PF00730 HhH-GPD superfamily base excision DNA repair protein SPYCW_RS18445 PF07687 Peptidase dimerisation domain SPYCW_RS18445 PF01546 Peptidase family M20/M25/M40 SPYCW_RS18450 PF13977 BetI-type transcriptional repressor, C-terminal SPYCW_RS18450 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS18455 PF00355 Rieske [2Fe-2S] domain SPYCW_RS18455 PF00848 Ring hydroxylating alpha subunit (catalytic domain) SPYCW_RS18465 PF13520 Amino acid permease SPYCW_RS18475 PF13181 Tetratricopeptide repeat SPYCW_RS18485 PF01435 Peptidase family M48 SPYCW_RS18490 PF00575 S1 RNA binding domain SPYCW_RS18490 PF10150 Ribonuclease E/G family SPYCW_RS18490 PF12111 Polyribonucleotide phosphorylase C terminal SPYCW_RS18495 PF01520 N-acetylmuramoyl-L-alanine amidase SPYCW_RS18495 PF11741 AMIN domain SPYCW_RS18500 PF01565 FAD binding domain SPYCW_RS18500 PF04030 D-arabinono-1,4-lactone oxidase SPYCW_RS18505 PF14031 Putative serine dehydratase domain SPYCW_RS18505 PF01168 Alanine racemase, N-terminal domain SPYCW_RS18510 PF00440 Bacterial regulatory proteins, tetR family SPYCW_RS18515 PF17092 Penicillin-binding protein OB-like domain SPYCW_RS18515 PF00905 Penicillin binding protein transpeptidase domain SPYCW_RS18515 PF00912 Transglycosylase SPYCW_RS18520 PF03462 PCRF domain SPYCW_RS18520 PF00472 RF-1 domain SPYCW_RS18525 PF01728 FtsJ-like methyltransferase SPYCW_RS18535 PF00899 ThiF family SPYCW_RS18540 PF00692 dUTPase SPYCW_RS18545 PF04127 DNA / pantothenate metabolism flavoprotein SPYCW_RS18545 PF02441 Flavoprotein SPYCW_RS18560 PF03109 ABC1 family SPYCW_RS18565 PF01209 ubiE/COQ5 methyltransferase family SPYCW_RS18570 PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain SPYCW_RS18570 PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain SPYCW_RS18570 PF06827 Zinc finger found in FPG and IleRS SPYCW_RS18575 PF01649 Ribosomal protein S20 SPYCW_RS18580 PF10134 Replication initiator protein A SPYCW_RS18595 PF08401 Domain of unknown function (DUF1738) SPYCW_RS18595 PF18818 Metallopeptidase superfamily domain SPYCW_RS18595 PF13362 Toprim domain SPYCW_RS18610 PF02796 Helix-turn-helix domain of resolvase SPYCW_RS18610 PF00239 Resolvase, N terminal domain SPYCW_RS18625 PF13610 DDE domain SPYCW_RS18670 PF01381 Helix-turn-helix SPYCW_RS18675 PF02384 N-6 DNA Methylase SPYCW_RS18680 PF09572 XamI restriction endonuclease SPYCW_RS18725 PF02534 Type IV secretory system Conjugative DNA transfer