locus-tag	class	description
CHN51_RS00035	COG5489	Protein of unknown function (DUF736)
CHN51_RS00060	COG1475	DNA binding
CHN51_RS00075	COG4974	Belongs to the 'phage' integrase family
CHN51_RS00080	COG4974	Belongs to the 'phage' integrase family
CHN51_RS00085	COG4974	Belongs to the 'phage' integrase family
CHN51_RS00095	COG3547	Transposase (IS116 IS110 IS902 family)
CHN51_RS00140	COG5654	RES domain protein
CHN51_RS00145	COG5642	Protein of unknown function (DUF2384)
CHN51_RS00190	COG1538	Outer membrane efflux protein
CHN51_RS00220	COG0633	Ferredoxin
CHN51_RS00230	COG2188	Transcriptional regulator
CHN51_RS00235	COG2070	2-Nitropropane dioxygenase
CHN51_RS00255	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS00260	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS00270	COG2072	flavoprotein involved in K transport
CHN51_RS00295	COG4771	TonB-dependent receptor
CHN51_RS00370	COG3239	Fatty acid desaturase
CHN51_RS00395	COG2909	trisaccharide binding
CHN51_RS00600	COG0629	single-stranded DNA binding
CHN51_RS00615	COG1276	copper resistance
CHN51_RS00645	COG0833	amino acid
CHN51_RS00655	COG0626	cystathionine gamma-synthase activity
CHN51_RS00660	COG0583	DNA-binding transcription factor activity
CHN51_RS00710	COG0629	single-stranded DNA binding
CHN51_RS00740	COG4227	nucleotidyltransferase activity
CHN51_RS00765	COG0741	lytic transglycosylase activity
CHN51_RS00770	COG0582	viral genome integration into host DNA
CHN51_RS00780	COG2211	Major facilitator Superfamily
CHN51_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS00810	COG0583	DNA-binding transcription factor activity
CHN51_RS00830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CHN51_RS00840	COG3383	formate dehydrogenase (NAD+) activity
CHN51_RS00855	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CHN51_RS00860	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CHN51_RS00870	COG1024	Enoyl-CoA hydratase
CHN51_RS00880	COG0667	Aldo Keto reductase
CHN51_RS00910	COG2159	amidohydrolase
CHN51_RS00920	COG0583	DNA-binding transcription factor activity
CHN51_RS00925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CHN51_RS00935	COG3618	amidohydrolase
CHN51_RS00945	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CHN51_RS00960	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CHN51_RS00965	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS00985	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS00990	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS01000	COG2211	Major facilitator Superfamily
CHN51_RS01005	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS01010	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CHN51_RS01020	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS01040	COG1505	serine-type exopeptidase activity
CHN51_RS01045	COG0203	ribosomal protein L17
CHN51_RS01050	COG0202	RNA polymerase activity
CHN51_RS01055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHN51_RS01060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHN51_RS01070	COG0189	ligase activity
CHN51_RS01075	COG0189	ligase activity
CHN51_RS01075	COG4067	protein conserved in archaea
CHN51_RS01090	COG0563	adenylate kinase activity
CHN51_RS01095	COG0201	protein transport
CHN51_RS01100	COG0200	Binds to the 23S rRNA
CHN51_RS01105	COG1841	ribosomal large subunit assembly
CHN51_RS01110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHN51_RS01115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHN51_RS01120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHN51_RS01125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHN51_RS01130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHN51_RS01135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHN51_RS01140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHN51_RS01145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHN51_RS01150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHN51_RS01155	COG0255	Belongs to the universal ribosomal protein uL29 family
CHN51_RS01160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHN51_RS01165	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHN51_RS01170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHN51_RS01175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHN51_RS01180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHN51_RS01185	COG0089	rRNA binding
CHN51_RS01190	COG0088	Forms part of the polypeptide exit tunnel
CHN51_RS01195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHN51_RS01200	COG0051	transcription antitermination factor activity, RNA binding
CHN51_RS01205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHN51_RS01210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHN51_RS01215	COG0049	tRNA binding
CHN51_RS01220	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHN51_RS01245	COG4771	TonB-dependent receptor
CHN51_RS01250	COG3300	MHYT domain
CHN51_RS01250	COG5001	Diguanylate cyclase
CHN51_RS01265	COG1755	Isoprenylcysteine carboxyl methyltransferase
CHN51_RS01270	COG3424	synthase
CHN51_RS01320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHN51_RS01330	COG0746	molybdenum cofactor guanylyltransferase activity
CHN51_RS01340	COG1473	amidohydrolase
CHN51_RS01355	COG3153	acetyltransferase
CHN51_RS01360	COG0450	alkyl hydroperoxide reductase
CHN51_RS01370	COG1228	amidohydrolase
CHN51_RS01375	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHN51_RS01380	COG0067	glutamate synthase
CHN51_RS01380	COG0069	glutamate synthase activity
CHN51_RS01380	COG0070	glutamate synthase
CHN51_RS01455	COG1309	transcriptional regulator
CHN51_RS01475	COG2211	Major facilitator Superfamily
CHN51_RS01530	COG1125	glycine betaine transport
CHN51_RS01530	COG0517	IMP dehydrogenase activity
CHN51_RS01540	COG1607	acyl-coa hydrolase
CHN51_RS01560	COG1309	transcriptional regulator
CHN51_RS01575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CHN51_RS01605	COG1058	Belongs to the CinA family
CHN51_RS01605	COG1546	Belongs to the CinA family
CHN51_RS01615	COG0024	Methionine aminopeptidase
CHN51_RS01630	COG3668	Plasmid stabilization system
CHN51_RS01635	COG3609	addiction module antidote protein, CC2985 family
CHN51_RS01645	COG2885	chlorophyll binding
CHN51_RS01665	COG0174	glutamine synthetase
CHN51_RS01685	COG0729	surface antigen
CHN51_RS01715	COG1454	alcohol dehydrogenase
CHN51_RS01745	COG4774	siderophore transport
CHN51_RS01745	COG1629	transport
CHN51_RS01750	COG0588	phosphoglycerate mutase activity
CHN51_RS01760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHN51_RS01765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CHN51_RS01780	COG0196	riboflavin kinase activity
CHN51_RS01785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHN51_RS01790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHN51_RS01800	COG1872	DUF167
CHN51_RS01805	COG0138	bifunctional purine biosynthesis protein purh
CHN51_RS01815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHN51_RS01820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHN51_RS01820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHN51_RS01855	COG3634	alkyl hydroperoxide reductase activity
CHN51_RS01860	COG0501	Belongs to the peptidase M48B family
CHN51_RS01910	COG2835	tetraacyldisaccharide 4'-kinase activity
CHN51_RS01935	COG2003	Belongs to the UPF0758 family
CHN51_RS01945	COG2095	MarC family integral membrane protein
CHN51_RS01955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHN51_RS01965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHN51_RS01970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHN51_RS01975	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHN51_RS01980	COG0281	malic enzyme
CHN51_RS01980	COG0280	phosphate acetyltransferase
CHN51_RS02000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CHN51_RS02010	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHN51_RS02030	COG1127	ABC transporter
CHN51_RS02090	COG1215	transferase activity, transferring glycosyl groups
CHN51_RS02105	COG0471	metal ion transport
CHN51_RS02115	COG0308	aminopeptidase N
CHN51_RS02120	COG0501	Belongs to the peptidase M48B family
CHN51_RS02145	COG1131	(ABC) transporter
CHN51_RS02190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHN51_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS02220	COG1174	glycine betaine transport
CHN51_RS02225	COG0517	IMP dehydrogenase activity
CHN51_RS02225	COG1125	glycine betaine transport
CHN51_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS02235	COG2154	pterin-4-alpha-carbinolamine dehydratase
CHN51_RS02240	COG4133	protoheme IX ABC transporter activity
CHN51_RS02245	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHN51_RS02250	COG1309	transcriptional regulator
CHN51_RS02255	COG1538	Outer membrane efflux protein
CHN51_RS02290	COG1959	2 iron, 2 sulfur cluster binding
CHN51_RS02300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHN51_RS02315	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CHN51_RS02320	COG3128	pkhd-type hydroxylase
CHN51_RS02325	COG4774	siderophore transport
CHN51_RS02335	COG0848	biopolymer transport protein
CHN51_RS02360	COG0367	asparagine synthase
CHN51_RS02375	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS02385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHN51_RS02390	COG1301	dicarboxylic acid transport
CHN51_RS02395	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CHN51_RS02405	COG4206	TonB-dependent receptor
CHN51_RS02410	COG0583	DNA-binding transcription factor activity
CHN51_RS02420	COG0463	Glycosyl transferase, family 2
CHN51_RS02435	COG2382	esterase
CHN51_RS02435	COG3507	Belongs to the glycosyl hydrolase 43 family
CHN51_RS02435	COG3693	PFAM glycoside hydrolase, family 10
CHN51_RS02450	COG0800	Aldolase
CHN51_RS02455	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS02510	COG0824	Thioesterase
CHN51_RS02520	COG0006	proline dipeptidase activity
CHN51_RS02545	COG0181	hydroxymethylbilane synthase activity
CHN51_RS02550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHN51_RS02555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHN51_RS02565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHN51_RS02580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHN51_RS02585	COG4152	abc transporter atp-binding protein
CHN51_RS02630	COG0531	amino acid
CHN51_RS02645	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHN51_RS02650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHN51_RS02685	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHN51_RS02690	COG1446	asparaginase
CHN51_RS02695	COG3228	Belongs to the MtfA family
CHN51_RS02735	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CHN51_RS02745	COG1002	Type II restriction enzyme, methylase subunits
CHN51_RS02755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CHN51_RS02770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHN51_RS02785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHN51_RS02800	COG0546	phosphoglycolate phosphatase activity
CHN51_RS02815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHN51_RS02825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHN51_RS02830	COG2010	Cytochrome c
CHN51_RS02830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHN51_RS02835	COG1832	CoA-binding protein
CHN51_RS02840	COG0489	protein tyrosine kinase activity
CHN51_RS02845	COG0330	HflC and HflK could
CHN51_RS02850	COG0330	HflC and HflK could
CHN51_RS02870	COG0433	COG0433 Predicted ATPase
CHN51_RS02885	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CHN51_RS02890	COG3046	protein related to deoxyribodipyrimidine photolyase
CHN51_RS02895	COG2897	thiosulfate sulfurtransferase activity
CHN51_RS02900	COG0626	cystathionine gamma-synthase activity
CHN51_RS02905	COG0668	transmembrane transport
CHN51_RS02915	COG4172	Belongs to the ABC transporter superfamily
CHN51_RS02920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHN51_RS02930	COG0596	Alpha beta hydrolase
CHN51_RS02935	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHN51_RS02950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CHN51_RS02965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHN51_RS02975	COG0745	RESPONSE REGULATOR receiver
CHN51_RS02980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CHN51_RS02985	COG0243	molybdopterin cofactor binding
CHN51_RS03000	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHN51_RS03005	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHN51_RS03070	COG0456	acetyltransferase
CHN51_RS03075	COG0708	Exodeoxyribonuclease III
CHN51_RS03080	COG0316	Belongs to the HesB IscA family
CHN51_RS03085	COG0739	heme binding
CHN51_RS03090	COG2833	Protein of unknown function (DUF455)
CHN51_RS03095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHN51_RS03100	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CHN51_RS03105	COG0343	queuine tRNA-ribosyltransferase activity
CHN51_RS03120	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHN51_RS03130	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHN51_RS03135	COG0142	geranyltranstransferase activity
CHN51_RS03140	COG1722	exodeoxyribonuclease VII activity
CHN51_RS03165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHN51_RS03170	COG2852	Protein conserved in bacteria
CHN51_RS03190	COG2311	Membrane
CHN51_RS03215	COG1160	GTP binding
CHN51_RS03230	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHN51_RS03240	COG0584	glycerophosphoryl diester phosphodiesterase
CHN51_RS03250	COG1988	membrane-bound metal-dependent
CHN51_RS03255	COG1393	Belongs to the ArsC family
CHN51_RS03260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHN51_RS03295	COG0519	Catalyzes the synthesis of GMP from XMP
CHN51_RS03295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHN51_RS03305	COG0318	PFAM AMP-dependent synthetase and ligase
CHN51_RS03335	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS03340	COG4206	TonB-dependent receptor
CHN51_RS03345	COG4206	TonB-dependent receptor
CHN51_RS03360	COG2130	NADP-dependent
CHN51_RS03370	COG0183	Belongs to the thiolase family
CHN51_RS03390	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS03395	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS03400	COG2130	NADP-dependent
CHN51_RS03405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHN51_RS03410	COG0022	dehydrogenase e1 component
CHN51_RS03435	COG0625	glutathione transferase activity
CHN51_RS03450	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS03465	COG1024	Enoyl-CoA hydratase
CHN51_RS03510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHN51_RS03515	COG0590	tRNA wobble adenosine to inosine editing
CHN51_RS03520	COG3279	Response regulator of the LytR AlgR family
CHN51_RS03525	COG3275	phosphorelay sensor kinase activity
CHN51_RS03555	COG0545	Peptidyl-prolyl cis-trans isomerase
CHN51_RS03560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHN51_RS03565	COG0235	Class ii aldolase
CHN51_RS03585	COG5001	Diguanylate cyclase
CHN51_RS03590	COG0318	PFAM AMP-dependent synthetase and ligase
CHN51_RS03600	COG1278	Cold shock
CHN51_RS03620	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CHN51_RS03625	COG0583	DNA-binding transcription factor activity
CHN51_RS03635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHN51_RS03645	COG2832	Protein of unknown function (DUF454)
CHN51_RS03670	COG0346	lactoylglutathione lyase activity
CHN51_RS03700	COG0250	Participates in transcription elongation, termination and antitermination
CHN51_RS03705	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHN51_RS03710	COG0081	regulation of translation
CHN51_RS03725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHN51_RS03730	COG0222	ribosome binding
CHN51_RS03740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHN51_RS03745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHN51_RS03750	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CHN51_RS03760	COG1368	sulfuric ester hydrolase activity
CHN51_RS03765	COG0085	RNA polymerase activity
CHN51_RS03770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHN51_RS03780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CHN51_RS03785	COG1741	Belongs to the pirin family
CHN51_RS03790	COG0583	DNA-binding transcription factor activity
CHN51_RS03795	COG1280	lysine exporter protein (LysE YggA)
CHN51_RS03810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHN51_RS03815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHN51_RS03830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHN51_RS03835	COG0009	L-threonylcarbamoyladenylate synthase
CHN51_RS03840	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS03870	COG2226	methyltransferase
CHN51_RS03880	COG1329	Transcriptional regulator
CHN51_RS03885	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CHN51_RS03890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHN51_RS03900	COG0739	heme binding
CHN51_RS03905	COG0113	porphobilinogen synthase activity
CHN51_RS03915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CHN51_RS03920	COG4106	trans-aconitate 2-methyltransferase activity
CHN51_RS03935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHN51_RS03940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHN51_RS03955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHN51_RS03965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHN51_RS03970	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CHN51_RS04000	COG3275	phosphorelay sensor kinase activity
CHN51_RS04020	COG4771	TonB-dependent receptor
CHN51_RS04055	COG3474	cytochrome
CHN51_RS04080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHN51_RS04085	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CHN51_RS04090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHN51_RS04095	COG1301	dicarboxylic acid transport
CHN51_RS04100	COG3273	potassium ion transport
CHN51_RS04100	COG0471	metal ion transport
CHN51_RS04105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHN51_RS04110	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CHN51_RS04115	COG1295	ribonuclease BN
CHN51_RS04120	COG0484	heat shock protein binding
CHN51_RS04130	COG0259	pyridoxamine-phosphate oxidase activity
CHN51_RS04150	COG0482	sulfurtransferase activity
CHN51_RS04170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHN51_RS04180	COG2733	membrane
CHN51_RS04185	COG2902	Dehydrogenase
CHN51_RS04200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHN51_RS04205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHN51_RS04215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHN51_RS04230	COG1335	isochorismatase
CHN51_RS04245	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS04255	COG2226	methyltransferase
CHN51_RS04300	COG0277	FAD linked oxidase domain protein
CHN51_RS04330	COG2030	dehydratase
CHN51_RS04335	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS04340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHN51_RS04350	COG2186	Transcriptional regulator
CHN51_RS04365	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CHN51_RS04370	COG0154	amidase activity
CHN51_RS04380	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS04390	COG1024	Enoyl-CoA hydratase
CHN51_RS04425	COG2130	NADP-dependent
CHN51_RS04440	COG4771	TonB-dependent receptor
CHN51_RS04455	COG2226	methyltransferase
CHN51_RS04460	COG0640	Transcriptional regulator
CHN51_RS04465	COG0450	alkyl hydroperoxide reductase
CHN51_RS04480	COG2391	methyltransferase activity
CHN51_RS04495	COG1271	oxidase subunit
CHN51_RS04500	COG1294	oxidase, subunit
CHN51_RS04510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHN51_RS04510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHN51_RS04515	COG3706	GGDEF domain
CHN51_RS04550	COG2130	NADP-dependent
CHN51_RS04555	COG1234	tRNA 3'-trailer cleavage
CHN51_RS04560	COG1760	l-serine dehydratase
CHN51_RS04570	COG0459	protein refolding
CHN51_RS04575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHN51_RS04610	COG0616	signal peptide processing
CHN51_RS04630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHN51_RS04635	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHN51_RS04640	COG0567	Dehydrogenase, E1 component
CHN51_RS04650	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHN51_RS04660	COG0039	L-malate dehydrogenase activity
CHN51_RS04675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CHN51_RS04690	COG0657	acetylesterase activity
CHN51_RS04695	COG2244	polysaccharide biosynthetic process
CHN51_RS04700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHN51_RS04705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHN51_RS04710	COG1612	heme a metabolic process
CHN51_RS04730	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHN51_RS04740	COG2171	N-acyltransferase activity
CHN51_RS04745	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CHN51_RS04750	COG2255	four-way junction helicase activity
CHN51_RS04760	COG0632	four-way junction helicase activity
CHN51_RS04765	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CHN51_RS04775	COG0217	transcriptional regulatory protein
CHN51_RS04780	COG0393	Putative heavy-metal-binding
CHN51_RS04800	COG0469	pyruvate kinase activity
CHN51_RS04810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHN51_RS04825	COG2866	Carboxypeptidase
CHN51_RS04835	COG3311	Transcriptional regulator
CHN51_RS04885	COG0582	viral genome integration into host DNA
CHN51_RS04905	COG0686	Belongs to the AlaDH PNT family
CHN51_RS04925	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CHN51_RS04930	COG1137	ATPase activity
CHN51_RS04955	COG1278	Cold shock
CHN51_RS04965	COG0783	Belongs to the Dps family
CHN51_RS04970	COG2119	membrane
CHN51_RS04980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHN51_RS05020	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHN51_RS05025	COG1192	Involved in chromosome partitioning
CHN51_RS05055	COG0123	including yeast histone deacetylase and acetoin utilization protein
CHN51_RS05060	COG0628	permease
CHN51_RS05065	COG1201	RNA secondary structure unwinding
CHN51_RS05095	COG1054	Belongs to the UPF0176 family
CHN51_RS05110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CHN51_RS05115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHN51_RS05125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHN51_RS05145	COG0495	leucyl-tRNA aminoacylation
CHN51_RS05165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHN51_RS05180	COG2983	Belongs to the UPF0260 family
CHN51_RS05185	COG1999	signal sequence binding
CHN51_RS05190	COG0666	response to abiotic stimulus
CHN51_RS05200	COG3773	Cell wall hydrolase
CHN51_RS05200	COG3409	Peptidoglycan-binding domain 1 protein
CHN51_RS05215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHN51_RS05220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHN51_RS05225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHN51_RS05230	COG0237	dephospho-CoA kinase activity
CHN51_RS05235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHN51_RS05240	COG0424	maF-like protein
CHN51_RS05245	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CHN51_RS05250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHN51_RS05255	COG1981	membrane
CHN51_RS05260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CHN51_RS05265	COG2329	Antibiotic biosynthesis monooxygenase
CHN51_RS05270	COG0861	Integral membrane protein TerC family
CHN51_RS05295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHN51_RS05300	COG0445	tRNA wobble uridine modification
CHN51_RS05305	COG0357	Ribosomal RNA small subunit methyltransferase G
CHN51_RS05350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHN51_RS05355	COG2070	2-Nitropropane dioxygenase
CHN51_RS05360	COG4770	biotin carboxylase activity
CHN51_RS05365	COG1024	Enoyl-CoA hydratase
CHN51_RS05370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHN51_RS05375	COG1309	transcriptional regulator
CHN51_RS05380	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHN51_RS05380	COG1024	Enoyl-CoA hydratase
CHN51_RS05385	COG0183	Belongs to the thiolase family
CHN51_RS05390	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS05415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHN51_RS05465	COG0714	Associated with various cellular activities
CHN51_RS05485	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS05490	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS05500	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS05510	COG2814	Major facilitator Superfamily
CHN51_RS05520	COG1053	succinate dehydrogenase
CHN51_RS05535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHN51_RS05540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHN51_RS05610	COG2884	Cell division ATP-binding protein ftsE
CHN51_RS05650	COG0662	Cupin 2, conserved barrel domain protein
CHN51_RS05655	COG2271	Major facilitator Superfamily
CHN51_RS05660	COG0287	Prephenate dehydrogenase
CHN51_RS05665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHN51_RS05670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHN51_RS05675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHN51_RS05675	COG2813	Specifically methylates the guanine in position
CHN51_RS05680	COG2161	toxin-antitoxin pair type II binding
CHN51_RS05685	COG4115	mRNA cleavage
CHN51_RS05695	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CHN51_RS05700	COG0072	phenylalanine-tRNA ligase activity
CHN51_RS05705	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHN51_RS05710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHN51_RS05715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHN51_RS05730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHN51_RS05740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHN51_RS05740	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CHN51_RS05775	COG1482	cell wall glycoprotein biosynthetic process
CHN51_RS05800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHN51_RS05810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHN51_RS05905	COG0110	maltose O-acetyltransferase activity
CHN51_RS05970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHN51_RS06025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHN51_RS06030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHN51_RS06070	COG0719	Fe-S assembly protein
CHN51_RS06080	COG0396	ATPase activity
CHN51_RS06085	COG0719	Fe-S assembly protein
CHN51_RS06095	COG2151	metal-sulfur cluster biosynthetic enzyme
CHN51_RS06100	COG0316	Belongs to the HesB IscA family
CHN51_RS06105	COG0330	HflC and HflK could
CHN51_RS06135	COG2086	electron transfer activity
CHN51_RS06140	COG0045	succinate-CoA ligase (ADP-forming) activity
CHN51_RS06145	COG0456	acetyltransferase
CHN51_RS06160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CHN51_RS06170	COG0124	histidyl-tRNA synthetase
CHN51_RS06175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHN51_RS06180	COG2890	protein-(glutamine-N5) methyltransferase activity
CHN51_RS06195	COG0418	dihydroorotase activity
CHN51_RS06200	COG2962	Rard protein
CHN51_RS06230	COG2124	cytochrome p450
CHN51_RS06245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHN51_RS06250	COG0180	Tryptophanyl-tRNA synthetase
CHN51_RS06260	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CHN51_RS06280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHN51_RS06290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHN51_RS06295	COG0706	membrane insertase activity
CHN51_RS06300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHN51_RS06305	COG0594	ribonuclease P activity
CHN51_RS06310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CHN51_RS06335	COG0739	heme binding
CHN51_RS06340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHN51_RS06345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHN51_RS06350	COG0799	negative regulation of ribosome biogenesis
CHN51_RS06355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHN51_RS06365	COG0793	Belongs to the peptidase S41A family
CHN51_RS06375	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CHN51_RS06400	COG2070	2-Nitropropane dioxygenase
CHN51_RS06405	COG0527	aspartate kinase activity
CHN51_RS06410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHN51_RS06455	COG1968	undecaprenyl-diphosphatase activity
CHN51_RS06510	COG0741	lytic transglycosylase activity
CHN51_RS06535	COG4974	Belongs to the 'phage' integrase family
CHN51_RS06540	COG4974	Belongs to the 'phage' integrase family
CHN51_RS06545	COG4974	Belongs to the 'phage' integrase family
CHN51_RS06550	COG4227	nucleotidyltransferase activity
CHN51_RS06755	COG3415	Transposase
CHN51_RS06760	COG3335	DDE superfamily endonuclease
CHN51_RS06775	COG2272	Belongs to the type-B carboxylesterase lipase family
CHN51_RS06780	COG4206	TonB-dependent receptor
CHN51_RS06800	COG0318	PFAM AMP-dependent synthetase and ligase
CHN51_RS06820	COG3971	2-oxopent-4-enoate hydratase activity
CHN51_RS06830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHN51_RS06870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CHN51_RS06875	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS06890	COG0163	prenyltransferase activity
CHN51_RS06895	COG4771	TonB-dependent receptor
CHN51_RS06910	COG4638	Rieske (2fe-2S)
CHN51_RS06915	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CHN51_RS06945	COG4638	Rieske (2fe-2S)
CHN51_RS06950	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CHN51_RS06980	COG3971	2-oxopent-4-enoate hydratase activity
CHN51_RS07000	COG1942	4-Oxalocrotonate Tautomerase
CHN51_RS07010	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS07040	COG4638	Rieske (2fe-2S)
CHN51_RS07045	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CHN51_RS07200	COG5001	Diguanylate cyclase
CHN51_RS07200	COG3300	MHYT domain
CHN51_RS07305	COG2814	Major facilitator Superfamily
CHN51_RS07335	COG1484	DNA-dependent DNA replication
CHN51_RS07385	COG4206	TonB-dependent receptor
CHN51_RS07385	COG1629	transport
CHN51_RS07410	COG4771	TonB-dependent receptor
CHN51_RS07420	COG2205	protein histidine kinase activity
CHN51_RS07420	COG0784	Response regulator, receiver
CHN51_RS07420	COG5002	protein histidine kinase activity
CHN51_RS07425	COG0745	RESPONSE REGULATOR receiver
CHN51_RS07450	COG2211	Major facilitator Superfamily
CHN51_RS07485	COG0673	inositol 2-dehydrogenase activity
CHN51_RS07510	COG0006	proline dipeptidase activity
CHN51_RS07520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHN51_RS07540	COG2755	lipolytic protein G-D-S-L family
CHN51_RS07540	COG0657	acetylesterase activity
CHN51_RS07580	COG1335	isochorismatase
CHN51_RS07585	COG0066	3-isopropylmalate dehydratase activity
CHN51_RS07590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHN51_RS07610	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS07615	COG1414	Transcriptional regulator
CHN51_RS07625	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CHN51_RS07635	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS07640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHN51_RS07670	COG0776	regulation of translation
CHN51_RS07680	COG0588	phosphoglycerate mutase activity
CHN51_RS07685	COG1199	ATP-dependent helicase activity
CHN51_RS07700	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CHN51_RS07720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHN51_RS07750	COG0439	Biotin carboxylase
CHN51_RS07755	COG0511	ligase activity, forming carbon-carbon bonds
CHN51_RS07760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHN51_RS07765	COG2022	thiamine diphosphate biosynthetic process
CHN51_RS07780	COG3300	MHYT domain
CHN51_RS07780	COG5001	Diguanylate cyclase
CHN51_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS07815	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS07820	COG3383	formate dehydrogenase (NAD+) activity
CHN51_RS07825	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS07835	COG1024	Enoyl-CoA hydratase
CHN51_RS07865	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS07870	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CHN51_RS07875	COG1024	Enoyl-CoA hydratase
CHN51_RS07910	COG0183	Belongs to the thiolase family
CHN51_RS07920	COG1024	Enoyl-CoA hydratase
CHN51_RS07935	COG0625	glutathione transferase activity
CHN51_RS07945	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS07950	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS07965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHN51_RS07970	COG1522	sequence-specific DNA binding
CHN51_RS07980	COG1522	sequence-specific DNA binding
CHN51_RS08005	COG1522	sequence-specific DNA binding
CHN51_RS08025	COG2271	Major facilitator Superfamily
CHN51_RS08030	COG5001	Diguanylate cyclase
CHN51_RS08060	COG0783	Belongs to the Dps family
CHN51_RS08065	COG0693	protein deglycase activity
CHN51_RS08075	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHN51_RS08095	COG1793	dna ligase
CHN51_RS08100	COG2267	carboxylic ester hydrolase activity
CHN51_RS08120	COG0798	PFAM Bile acid sodium symporter
CHN51_RS08140	COG1629	transport
CHN51_RS08140	COG4771	TonB-dependent receptor
CHN51_RS08165	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS08180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHN51_RS08195	COG0596	Alpha beta hydrolase
CHN51_RS08205	COG1309	transcriptional regulator
CHN51_RS08220	COG4206	TonB-dependent receptor
CHN51_RS08225	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHN51_RS08230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHN51_RS08240	COG3268	Saccharopine dehydrogenase
CHN51_RS08245	COG0006	proline dipeptidase activity
CHN51_RS08265	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CHN51_RS08270	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS08275	COG2272	Belongs to the type-B carboxylesterase lipase family
CHN51_RS08310	COG0800	Aldolase
CHN51_RS08320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHN51_RS08345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHN51_RS08375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHN51_RS08380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CHN51_RS08415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHN51_RS08425	COG0756	dUTP diphosphatase activity
CHN51_RS08430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHN51_RS08440	COG2226	methyltransferase
CHN51_RS08445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHN51_RS08450	COG0268	Binds directly to 16S ribosomal RNA
CHN51_RS08460	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CHN51_RS08475	COG3909	cytochrome
CHN51_RS08480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHN51_RS08485	COG0165	Argininosuccinate lyase
CHN51_RS08495	COG0019	diaminopimelate decarboxylase activity
CHN51_RS08500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHN51_RS08500	COG1648	precorrin-2 dehydrogenase activity
CHN51_RS08515	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CHN51_RS08520	COG0668	transmembrane transport
CHN51_RS08525	COG0183	Belongs to the thiolase family
CHN51_RS08535	COG4948	Mandelate Racemase Muconate Lactonizing
CHN51_RS08570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHN51_RS08585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHN51_RS08590	COG0416	fatty acid biosynthetic process
CHN51_RS08595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHN51_RS08625	COG0277	FAD linked oxidase domain protein
CHN51_RS08635	COG0513	Belongs to the DEAD box helicase family
CHN51_RS08690	COG2814	Major facilitator Superfamily
CHN51_RS08705	COG1695	Transcriptional regulator
CHN51_RS08720	COG1238	metal cluster binding
CHN51_RS08725	COG1115	amino acid carrier protein
CHN51_RS08750	COG4695	Portal protein
CHN51_RS08855	COG0047	phosphoribosylformylglycinamidine synthase activity
CHN51_RS08860	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHN51_RS08870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHN51_RS08880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHN51_RS08900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHN51_RS08920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHN51_RS08925	COG0617	tRNA 3'-terminal CCA addition
CHN51_RS08950	COG2133	pyrroloquinoline quinone binding
CHN51_RS08960	COG0519	Catalyzes the synthesis of GMP from XMP
CHN51_RS08980	COG3264	Mechanosensitive ion channel
CHN51_RS08980	COG1196	nuclear chromosome segregation
CHN51_RS08985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHN51_RS09005	COG0668	transmembrane transport
CHN51_RS09025	COG0784	Response regulator, receiver
CHN51_RS09040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHN51_RS09065	COG2885	chlorophyll binding
CHN51_RS09090	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS09095	COG0800	Aldolase
CHN51_RS09100	COG0837	glucose binding
CHN51_RS09105	COG0129	dihydroxy-acid dehydratase activity
CHN51_RS09110	COG0363	glucosamine-6-phosphate deaminase activity
CHN51_RS09115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHN51_RS09125	COG1472	Belongs to the glycosyl hydrolase 3 family
CHN51_RS09145	COG2211	Major facilitator Superfamily
CHN51_RS09150	COG1609	Transcriptional regulator
CHN51_RS09165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHN51_RS09175	COG1573	uracil-dna glycosylase
CHN51_RS09185	COG1494	fructose-1,6-bisphosphatase
CHN51_RS09230	COG1132	(ABC) transporter
CHN51_RS09250	COG1846	Transcriptional regulator
CHN51_RS09255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHN51_RS09285	COG0583	DNA-binding transcription factor activity
CHN51_RS09315	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHN51_RS09320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHN51_RS09350	COG2217	Heavy metal translocating P-type atpase
CHN51_RS09360	COG1937	Protein conserved in bacteria
CHN51_RS09395	COG2132	Multicopper oxidase
CHN51_RS09445	COG1971	Probably functions as a manganese efflux pump
CHN51_RS09460	COG0671	phosphoesterase, PA-phosphatase related
CHN51_RS09500	COG0672	)-iron permease
CHN51_RS09515	COG0789	Transcriptional regulator
CHN51_RS09535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHN51_RS09565	COG5001	Diguanylate cyclase
CHN51_RS09575	COG0745	RESPONSE REGULATOR receiver
CHN51_RS09585	COG5002	protein histidine kinase activity
CHN51_RS09600	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHN51_RS09630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHN51_RS09655	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHN51_RS09660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CHN51_RS09690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHN51_RS09720	COG5001	Diguanylate cyclase
CHN51_RS09740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHN51_RS09755	COG1228	amidohydrolase
CHN51_RS09760	COG0791	NLP P60 protein
CHN51_RS09775	COG0736	holo-[acyl-carrier-protein] synthase activity
CHN51_RS09780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CHN51_RS09785	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHN51_RS09790	COG1565	acr, cog1565
CHN51_RS09790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHN51_RS09795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHN51_RS09800	COG0109	protoheme IX farnesyltransferase activity
CHN51_RS09805	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CHN51_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS09845	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CHN51_RS09850	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CHN51_RS09860	COG2066	Belongs to the glutaminase family
CHN51_RS09865	COG0028	Belongs to the TPP enzyme family
CHN51_RS09885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHN51_RS09890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHN51_RS09905	COG1459	type II secretion system
CHN51_RS09950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHN51_RS09970	COG0194	GDP metabolic process
CHN51_RS09975	COG0628	permease
CHN51_RS10000	COG0114	fumarate hydratase activity
CHN51_RS10010	COG0131	Imidazoleglycerol-phosphate dehydratase
CHN51_RS10015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHN51_RS10020	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHN51_RS10025	COG0107	imidazoleglycerol-phosphate synthase activity
CHN51_RS10035	COG0140	phosphoribosyl-ATP diphosphatase activity
CHN51_RS10045	COG0733	neurotransmitter:sodium symporter activity
CHN51_RS10050	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CHN51_RS10070	COG1595	DNA-templated transcription, initiation
CHN51_RS10085	COG0702	epimerase
CHN51_RS10110	COG1132	(ABC) transporter
CHN51_RS10115	COG3153	acetyltransferase
CHN51_RS10115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHN51_RS10140	COG2205	protein histidine kinase activity
CHN51_RS10140	COG0784	Response regulator, receiver
CHN51_RS10165	COG0436	Aminotransferase
CHN51_RS10170	COG0625	glutathione transferase activity
CHN51_RS10180	COG1024	Enoyl-CoA hydratase
CHN51_RS10190	COG2814	Major facilitator Superfamily
CHN51_RS10210	COG1215	transferase activity, transferring glycosyl groups
CHN51_RS10220	COG0730	response to heat
CHN51_RS10240	COG0525	valine-tRNA ligase activity
CHN51_RS10245	COG1024	Enoyl-CoA hydratase
CHN51_RS10250	COG1506	peptidase
CHN51_RS10250	COG0823	Involved in the tonB-independent uptake of proteins
CHN51_RS10265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHN51_RS10295	COG3483	tryptophan 2,3-dioxygenase activity
CHN51_RS10320	COG2197	response regulator
CHN51_RS10330	COG4946	Tricorn protease homolog
CHN51_RS10330	COG1506	peptidase
CHN51_RS10330	COG0823	Involved in the tonB-independent uptake of proteins
CHN51_RS10360	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS10410	COG2824	Alkylphosphonate utilization operon protein PhnA
CHN51_RS10425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHN51_RS10435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHN51_RS10440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHN51_RS10480	COG3706	GGDEF domain
CHN51_RS10485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHN51_RS10515	COG3328	transposase activity
CHN51_RS10540	COG1022	Amp-dependent synthetase and ligase
CHN51_RS10545	COG0405	Gamma-glutamyltransferase
CHN51_RS10550	COG0167	dihydroorotate dehydrogenase activity
CHN51_RS10555	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS10575	COG0659	secondary active sulfate transmembrane transporter activity
CHN51_RS10600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHN51_RS10610	COG0066	3-isopropylmalate dehydratase activity
CHN51_RS10615	COG3321	synthase
CHN51_RS10615	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS10615	COG0604	alcohol dehydrogenase
CHN51_RS10630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CHN51_RS10645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHN51_RS10660	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CHN51_RS10705	COG4166	transmembrane transport
CHN51_RS10725	COG0776	regulation of translation
CHN51_RS10730	COG0539	negative regulation of cytoplasmic translation
CHN51_RS10735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CHN51_RS10745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHN51_RS10770	COG2081	HI0933 family
CHN51_RS10780	COG1671	Belongs to the UPF0178 family
CHN51_RS10800	COG0667	Aldo Keto reductase
CHN51_RS10835	COG0789	Transcriptional regulator
CHN51_RS10845	COG3665	Urea carboxylase-associated protein
CHN51_RS10885	COG1194	a g-specific adenine glycosylase
CHN51_RS10890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHN51_RS10915	COG2239	Acts as a magnesium transporter
CHN51_RS10935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHN51_RS10945	COG2329	Antibiotic biosynthesis monooxygenase
CHN51_RS10955	COG0612	Peptidase, M16
CHN51_RS10965	COG2885	chlorophyll binding
CHN51_RS10970	COG0823	Involved in the tonB-independent uptake of proteins
CHN51_RS10990	COG0824	Thioesterase
CHN51_RS11000	COG0640	Transcriptional regulator
CHN51_RS11020	COG0556	nucleotide-excision repair
CHN51_RS11050	COG0646	methionine synthase
CHN51_RS11050	COG1410	methionine synthase
CHN51_RS11055	COG1410	methionine synthase
CHN51_RS11055	COG0646	methionine synthase
CHN51_RS11080	COG2367	Beta-lactamase
CHN51_RS11090	COG1758	RNA polymerase activity
CHN51_RS11100	COG0037	tRNA processing
CHN51_RS11115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHN51_RS11135	COG1902	pentaerythritol trinitrate reductase activity
CHN51_RS11190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHN51_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS11200	COG2885	chlorophyll binding
CHN51_RS11205	COG1253	flavin adenine dinucleotide binding
CHN51_RS11215	COG3047	cAMP biosynthetic process
CHN51_RS11215	COG2885	chlorophyll binding
CHN51_RS11240	COG1573	uracil-dna glycosylase
CHN51_RS11245	COG0668	transmembrane transport
CHN51_RS11275	COG2304	oxidoreductase activity
CHN51_RS11285	COG0641	radical SAM
CHN51_RS11310	COG0151	Belongs to the GarS family
CHN51_RS11315	COG1570	exodeoxyribonuclease VII activity
CHN51_RS11335	COG4771	TonB-dependent receptor
CHN51_RS11360	COG2366	antibiotic biosynthetic process
CHN51_RS11370	COG1064	alcohol dehydrogenase
CHN51_RS11380	COG1131	(ABC) transporter
CHN51_RS11395	COG0312	modulator of DNA gyrase
CHN51_RS11425	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHN51_RS11430	COG0347	Belongs to the P(II) protein family
CHN51_RS11435	COG0004	ammonium transporteR
CHN51_RS11460	COG0514	ATP-dependent DNA helicase (RecQ)
CHN51_RS11465	COG5265	(ABC) transporter
CHN51_RS11510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHN51_RS11510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHN51_RS11520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHN51_RS11520	COG1372	Participates in initiation and elongation during chromosome replication
CHN51_RS11570	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS11600	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS11615	COG0215	cysteine-tRNA ligase activity
CHN51_RS11655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHN51_RS11665	COG3654	unkown
CHN51_RS11690	COG0662	Cupin 2, conserved barrel domain protein
CHN51_RS11695	COG1741	Belongs to the pirin family
CHN51_RS11705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHN51_RS11710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHN51_RS11720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHN51_RS11730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CHN51_RS11735	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CHN51_RS11765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHN51_RS11770	COG0424	maF-like protein
CHN51_RS11780	COG0625	glutathione transferase activity
CHN51_RS11820	COG4964	Belongs to the GSP D family
CHN51_RS11845	COG3422	double-strand break repair
CHN51_RS11850	COG0328	RNA-DNA hybrid ribonuclease activity
CHN51_RS11855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CHN51_RS11860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHN51_RS11870	COG0018	arginyl-trna synthetase
CHN51_RS11880	COG1472	Belongs to the glycosyl hydrolase 3 family
CHN51_RS11885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CHN51_RS11890	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHN51_RS11895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHN51_RS11900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHN51_RS11905	COG0805	protein transport
CHN51_RS11915	COG4771	TonB-dependent receptor
CHN51_RS11925	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CHN51_RS11940	COG1024	Enoyl-CoA hydratase
CHN51_RS11960	COG2001	Belongs to the MraZ family
CHN51_RS11965	COG0275	rRNA processing
CHN51_RS11980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHN51_RS11985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHN51_RS11990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHN51_RS11995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHN51_RS12005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHN51_RS12010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHN51_RS12015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHN51_RS12020	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHN51_RS12025	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CHN51_RS12035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHN51_RS12045	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CHN51_RS12055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHN51_RS12060	COG0509	glycine decarboxylation via glycine cleavage system
CHN51_RS12065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHN51_RS12070	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHN51_RS12075	COG0385	Bile acid
CHN51_RS12085	COG0318	PFAM AMP-dependent synthetase and ligase
CHN51_RS12095	COG0583	DNA-binding transcription factor activity
CHN51_RS12120	COG2132	Multicopper oxidase
CHN51_RS12135	COG1937	Protein conserved in bacteria
CHN51_RS12150	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CHN51_RS12155	COG0697	spore germination
CHN51_RS12170	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS12175	COG1024	Enoyl-CoA hydratase
CHN51_RS12220	COG2244	polysaccharide biosynthetic process
CHN51_RS12225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHN51_RS12230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHN51_RS12235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHN51_RS12240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHN51_RS12245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHN51_RS12250	COG2169	Transcriptional regulator
CHN51_RS12250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHN51_RS12280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHN51_RS12290	COG3107	peptidoglycan biosynthetic process
CHN51_RS12295	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHN51_RS12300	COG0792	nuclease activity
CHN51_RS12305	COG0189	ligase activity
CHN51_RS12310	COG0586	Pfam SNARE associated Golgi protein
CHN51_RS12320	COG4206	TonB-dependent receptor
CHN51_RS12330	COG4974	Belongs to the 'phage' integrase family
CHN51_RS12340	COG0318	PFAM AMP-dependent synthetase and ligase
CHN51_RS12345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHN51_RS12355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHN51_RS12360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CHN51_RS12365	COG1420	regulation of RNA biosynthetic process
CHN51_RS12370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHN51_RS12395	COG2133	pyrroloquinoline quinone binding
CHN51_RS12400	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS12420	COG2610	gluconate transmembrane transporter activity
CHN51_RS12440	COG0534	Mate efflux family protein
CHN51_RS12450	COG3047	cAMP biosynthetic process
CHN51_RS12465	COG0443	Heat shock 70 kDa protein
CHN51_RS12470	COG0484	heat shock protein binding
CHN51_RS12490	COG4206	TonB-dependent receptor
CHN51_RS12515	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHN51_RS12515	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHN51_RS12545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHN51_RS12550	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHN51_RS12560	COG4974	Belongs to the 'phage' integrase family
CHN51_RS12565	COG0825	malonyl-CoA metabolic process
CHN51_RS12585	COG0494	nUDIX hydrolase
CHN51_RS12595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHN51_RS12600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHN51_RS12605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHN51_RS12640	COG4771	TonB-dependent receptor
CHN51_RS12645	COG3320	Male sterility
CHN51_RS12645	COG1022	Amp-dependent synthetase and ligase
CHN51_RS12650	COG2267	carboxylic ester hydrolase activity
CHN51_RS12660	COG1802	Transcriptional regulator
CHN51_RS12665	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS12675	COG0175	sulfate reduction
CHN51_RS12685	COG1218	3'(2'),5'-bisphosphate nucleotidase
CHN51_RS12700	COG2205	protein histidine kinase activity
CHN51_RS12700	COG0784	Response regulator, receiver
CHN51_RS12745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHN51_RS12750	COG1191	sigma factor activity
CHN51_RS12775	COG0235	Class ii aldolase
CHN51_RS12800	COG0450	alkyl hydroperoxide reductase
CHN51_RS12830	COG4191	Histidine kinase
CHN51_RS12835	COG4566	intracellular signal transduction
CHN51_RS12865	COG2010	Cytochrome c
CHN51_RS12895	COG0405	Gamma-glutamyltransferase
CHN51_RS12915	COG0513	Belongs to the DEAD box helicase family
CHN51_RS12920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHN51_RS12925	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS12955	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHN51_RS12960	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHN51_RS12970	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CHN51_RS12970	COG0662	Cupin 2, conserved barrel domain protein
CHN51_RS12975	COG1482	cell wall glycoprotein biosynthetic process
CHN51_RS12990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHN51_RS13010	COG0745	RESPONSE REGULATOR receiver
CHN51_RS13030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CHN51_RS13040	COG1137	ATPase activity
CHN51_RS13045	COG0427	acetyl-CoA hydrolase
CHN51_RS13065	COG2989	Protein conserved in bacteria
CHN51_RS13090	COG0745	RESPONSE REGULATOR receiver
CHN51_RS13105	COG2204	response regulator
CHN51_RS13130	COG0438	transferase activity, transferring glycosyl groups
CHN51_RS13135	COG1216	Glycosyl transferase, family 2
CHN51_RS13135	COG0463	Glycosyl transferase, family 2
CHN51_RS13140	COG0463	Glycosyl transferase, family 2
CHN51_RS13155	COG0784	Response regulator, receiver
CHN51_RS13155	COG2198	Histidine kinase
CHN51_RS13155	COG2205	protein histidine kinase activity
CHN51_RS13165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHN51_RS13165	COG1648	precorrin-2 dehydrogenase activity
CHN51_RS13170	COG0243	molybdopterin cofactor binding
CHN51_RS13180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHN51_RS13190	COG1116	anion transmembrane transporter activity
CHN51_RS13195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHN51_RS13200	COG1116	anion transmembrane transporter activity
CHN51_RS13200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHN51_RS13205	COG1116	anion transmembrane transporter activity
CHN51_RS13205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHN51_RS13210	COG2197	response regulator
CHN51_RS13225	COG0515	serine threonine protein kinase
CHN51_RS13235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHN51_RS13240	COG2032	superoxide dismutase activity
CHN51_RS13245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHN51_RS13250	COG0670	Belongs to the BI1 family
CHN51_RS13275	COG5507	3-demethylubiquinone-9 3-methyltransferase
CHN51_RS13280	COG0625	glutathione transferase activity
CHN51_RS13320	COG3321	synthase
CHN51_RS13320	COG0604	alcohol dehydrogenase
CHN51_RS13320	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS13335	COG0438	transferase activity, transferring glycosyl groups
CHN51_RS13355	COG0318	PFAM AMP-dependent synthetase and ligase
CHN51_RS13365	COG0753	catalase activity
CHN51_RS13380	COG0312	modulator of DNA gyrase
CHN51_RS13415	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHN51_RS13425	COG2268	Band 7 protein
CHN51_RS13440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CHN51_RS13455	COG3328	transposase activity
CHN51_RS13480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHN51_RS13560	COG3273	potassium ion transport
CHN51_RS13560	COG0471	metal ion transport
CHN51_RS13590	COG1278	Cold shock
CHN51_RS13595	COG2850	peptidyl-arginine hydroxylation
CHN51_RS13605	COG2267	carboxylic ester hydrolase activity
CHN51_RS13610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHN51_RS13635	COG1024	Enoyl-CoA hydratase
CHN51_RS13640	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS13655	COG3152	Membrane
CHN51_RS13665	COG1217	gtp-binding protein TYPA
CHN51_RS13680	COG4181	ATPase activity
CHN51_RS13700	COG0243	molybdopterin cofactor binding
CHN51_RS13715	COG0753	catalase activity
CHN51_RS13725	COG2135	peptidase activity
CHN51_RS13730	COG0248	Ppx GppA phosphatase
CHN51_RS13735	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CHN51_RS13740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHN51_RS13740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CHN51_RS13745	COG0501	Belongs to the peptidase M48B family
CHN51_RS13750	COG1530	ribonuclease E activity
CHN51_RS13760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHN51_RS13775	COG0704	Plays a role in the regulation of phosphate uptake
CHN51_RS13780	COG3746	phosphate-selective porin O and P
CHN51_RS13795	COG0481	GTPase activity
CHN51_RS13805	COG2264	protein methyltransferase activity
CHN51_RS13810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHN51_RS13815	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CHN51_RS13820	COG2080	2 iron, 2 sulfur cluster binding
CHN51_RS13830	COG2308	Evidence 4 Homologs of previously reported genes of
CHN51_RS13850	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CHN51_RS13870	COG0493	'glutamate synthase
CHN51_RS13875	COG0596	Alpha beta hydrolase
CHN51_RS13920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHN51_RS13925	COG0251	oxidation-reduction process
CHN51_RS13940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CHN51_RS13945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHN51_RS13955	COG0137	argininosuccinate synthase activity
CHN51_RS13965	COG0779	Required for maturation of 30S ribosomal subunits
CHN51_RS13980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHN51_RS13985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHN51_RS13990	COG1435	thymidine kinase activity
CHN51_RS14000	COG2226	methyltransferase
CHN51_RS14005	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHN51_RS14010	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHN51_RS14015	COG1185	polyribonucleotide nucleotidyltransferase activity
CHN51_RS14020	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHN51_RS14025	COG0497	DNA recombination
CHN51_RS14035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHN51_RS14045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHN51_RS14060	COG3186	Phenylalanine-4-hydroxylase
CHN51_RS14065	COG2264	protein methyltransferase activity
CHN51_RS14070	COG0488	(ABC) transporter
CHN51_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS14115	COG1280	lysine exporter protein (LysE YggA)
CHN51_RS14130	COG1304	FMN binding
CHN51_RS14135	COG4452	Inner membrane protein CreD
CHN51_RS14140	COG2321	neutral zinc metallopeptidase
CHN51_RS14145	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS14170	COG3800	Transcriptional regulator
CHN51_RS14170	COG1396	sequence-specific DNA binding
CHN51_RS14175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHN51_RS14185	COG2204	response regulator
CHN51_RS14195	COG2188	Transcriptional regulator
CHN51_RS14205	COG3104	oligopeptide transport
CHN51_RS14210	COG1228	amidohydrolase
CHN51_RS14215	COG0402	S-adenosylhomocysteine deaminase activity
CHN51_RS14220	COG0667	Aldo Keto reductase
CHN51_RS14225	COG1301	dicarboxylic acid transport
CHN51_RS14230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHN51_RS14240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CHN51_RS14240	COG0352	thiamine-phosphate diphosphorylase activity
CHN51_RS14240	COG0351	phosphomethylpyrimidine kinase
CHN51_RS14245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHN51_RS14260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHN51_RS14270	COG0688	phosphatidylethanolamine metabolic process
CHN51_RS14275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHN51_RS14280	COG2084	Dehydrogenase
CHN51_RS14285	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CHN51_RS14295	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CHN51_RS14305	COG1956	GAF domain-containing protein
CHN51_RS14320	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CHN51_RS14325	COG3268	Saccharopine dehydrogenase
CHN51_RS14330	COG0717	Belongs to the dCTP deaminase family
CHN51_RS14340	COG5328	Belongs to the UPF0262 family
CHN51_RS14345	COG0305	Participates in initiation and elongation during chromosome replication
CHN51_RS14350	COG0175	sulfate reduction
CHN51_RS14360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHN51_RS14370	COG1648	precorrin-2 dehydrogenase activity
CHN51_RS14370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHN51_RS14375	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS14380	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CHN51_RS14390	COG0438	transferase activity, transferring glycosyl groups
CHN51_RS14400	COG0454	-acetyltransferase
CHN51_RS14405	COG0004	ammonium transporteR
CHN51_RS14420	COG0183	Belongs to the thiolase family
CHN51_RS14435	COG4771	TonB-dependent receptor
CHN51_RS14440	COG4771	TonB-dependent receptor
CHN51_RS14455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHN51_RS14455	COG2010	Cytochrome c
CHN51_RS14460	COG0457	Tetratricopeptide repeat
CHN51_RS14465	COG4771	TonB-dependent receptor
CHN51_RS14500	COG1116	anion transmembrane transporter activity
CHN51_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS14555	COG3321	synthase
CHN51_RS14555	COG0604	alcohol dehydrogenase
CHN51_RS14565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHN51_RS14570	COG0438	transferase activity, transferring glycosyl groups
CHN51_RS14570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHN51_RS14575	COG2258	MOSC domain
CHN51_RS14580	COG1253	flavin adenine dinucleotide binding
CHN51_RS14585	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHN51_RS14590	COG1702	phosphate starvation-inducible protein PhoH
CHN51_RS14605	COG4957	zinc ion binding
CHN51_RS14620	COG0778	Nitroreductase
CHN51_RS14625	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CHN51_RS14630	COG0612	Peptidase, M16
CHN51_RS14640	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHN51_RS14645	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CHN51_RS14665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHN51_RS14670	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CHN51_RS14675	COG0314	molybdopterin synthase activity
CHN51_RS14680	COG0583	DNA-binding transcription factor activity
CHN51_RS14685	COG1045	serine acetyltransferase
CHN51_RS14695	COG0745	RESPONSE REGULATOR receiver
CHN51_RS14700	COG0704	Plays a role in the regulation of phosphate uptake
CHN51_RS14705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHN51_RS14715	COG0573	inorganic phosphate transmembrane transporter activity
CHN51_RS14725	COG5002	protein histidine kinase activity
CHN51_RS14750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHN51_RS14765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHN51_RS14790	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CHN51_RS14795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHN51_RS14800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHN51_RS14815	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CHN51_RS14820	COG0602	queuosine metabolic process
CHN51_RS14830	COG0321	lipoyl(octanoyl) transferase activity
CHN51_RS14845	COG0408	coproporphyrinogen oxidase activity
CHN51_RS14850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHN51_RS14855	COG0723	plastoquinol--plastocyanin reductase activity
CHN51_RS14870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHN51_RS14885	COG4529	Protein conserved in bacteria
CHN51_RS14895	COG0784	Response regulator, receiver
CHN51_RS14915	COG2205	protein histidine kinase activity
CHN51_RS14930	COG0488	(ABC) transporter
CHN51_RS14935	COG2852	Protein conserved in bacteria
CHN51_RS14940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHN51_RS14950	COG0288	reversible hydration of carbon dioxide
CHN51_RS14955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHN51_RS14965	COG1058	Belongs to the CinA family
CHN51_RS14965	COG1546	Belongs to the CinA family
CHN51_RS14975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHN51_RS14975	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHN51_RS14985	COG3852	Histidine kinase
CHN51_RS14990	COG2204	response regulator
CHN51_RS14995	COG5000	phosphorelay sensor kinase activity
CHN51_RS15000	COG2204	response regulator
CHN51_RS15005	COG1923	regulation of RNA biosynthetic process
CHN51_RS15010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHN51_RS15015	COG3956	TIGRFAM MazG family protein
CHN51_RS15025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHN51_RS15025	COG0321	lipoyl(octanoyl) transferase activity
CHN51_RS15030	COG0084	hydrolase, TatD family'
CHN51_RS15045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHN51_RS15050	COG1686	Belongs to the peptidase S11 family
CHN51_RS15060	COG2951	lytic endotransglycosylase activity
CHN51_RS15075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHN51_RS15080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHN51_RS15085	COG0183	Belongs to the thiolase family
CHN51_RS15090	COG1946	Acyl-CoA thioesterase
CHN51_RS15095	COG0318	PFAM AMP-dependent synthetase and ligase
CHN51_RS15100	COG1024	Enoyl-CoA hydratase
CHN51_RS15100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHN51_RS15110	COG3038	cytochrome b561
CHN51_RS15120	COG0583	DNA-binding transcription factor activity
CHN51_RS15130	COG2159	amidohydrolase
CHN51_RS15145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHN51_RS15155	COG0625	glutathione transferase activity
CHN51_RS15160	COG2124	cytochrome p450
CHN51_RS15180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHN51_RS15190	COG4771	TonB-dependent receptor
CHN51_RS15200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHN51_RS15205	COG0457	Tetratricopeptide repeat
CHN51_RS15230	COG4206	TonB-dependent receptor
CHN51_RS15240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHN51_RS15245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHN51_RS15250	COG1607	acyl-coa hydrolase
CHN51_RS15255	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHN51_RS15270	COG0557	exoribonuclease II activity
CHN51_RS15280	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CHN51_RS15285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHN51_RS15290	COG0477	Major facilitator Superfamily
CHN51_RS15295	COG4770	biotin carboxylase activity
CHN51_RS15300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHN51_RS15305	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHN51_RS15305	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHN51_RS15310	COG1024	Enoyl-CoA hydratase
CHN51_RS15315	COG0346	lactoylglutathione lyase activity
CHN51_RS15325	COG2354	Protein conserved in bacteria
CHN51_RS15335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHN51_RS15345	COG0166	Belongs to the GPI family
CHN51_RS15355	COG0571	ribonuclease III activity
CHN51_RS15360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHN51_RS15370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHN51_RS15370	COG1754	DNA topoisomerase type I activity
CHN51_RS15375	COG0758	DNA mediated transformation
CHN51_RS15375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHN51_RS15380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHN51_RS15385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHN51_RS15390	COG0156	8-amino-7-oxononanoate synthase activity
CHN51_RS15400	COG1748	Saccharopine dehydrogenase
CHN51_RS15425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHN51_RS15430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHN51_RS15430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHN51_RS15440	COG0129	dihydroxy-acid dehydratase activity
CHN51_RS15450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CHN51_RS15460	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CHN51_RS15460	COG0644	oxidoreductase
CHN51_RS15475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CHN51_RS15480	COG1678	Uncharacterized ACR, COG1678
CHN51_RS15485	COG0678	peroxiredoxin activity
CHN51_RS15485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHN51_RS15490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHN51_RS15530	COG2814	Major facilitator Superfamily
CHN51_RS15535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHN51_RS15540	COG0335	large ribosomal subunit rRNA binding
CHN51_RS15545	COG0336	Belongs to the RNA methyltransferase TrmD family
CHN51_RS15555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHN51_RS15560	COG0228	four-way junction DNA binding
CHN51_RS15565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHN51_RS15570	COG5001	Diguanylate cyclase
CHN51_RS15570	COG3300	MHYT domain
CHN51_RS15575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHN51_RS15580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHN51_RS15585	COG0552	protein localization to endoplasmic reticulum
CHN51_RS15595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHN51_RS15605	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CHN51_RS15610	COG1842	Phage shock protein A
CHN51_RS15650	COG2166	iron-sulfur cluster assembly
CHN51_RS15655	COG0484	heat shock protein binding
CHN51_RS15665	COG3023	N-Acetylmuramoyl-L-alanine amidase
CHN51_RS15680	COG0564	pseudouridine synthase activity
CHN51_RS15685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHN51_RS15700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHN51_RS15705	COG0740	serine-type endopeptidase activity
CHN51_RS15710	COG0740	serine-type endopeptidase activity
CHN51_RS15715	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHN51_RS15735	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHN51_RS15740	COG0154	amidase activity
CHN51_RS15745	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHN51_RS15755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHN51_RS15760	COG0540	Belongs to the ATCase OTCase family
CHN51_RS15765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHN51_RS15790	COG0560	Phosphoserine phosphatase
CHN51_RS15795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHN51_RS15800	COG0028	Belongs to the TPP enzyme family
CHN51_RS15805	COG0440	acetolactate synthase activity
CHN51_RS15810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHN51_RS15820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHN51_RS15835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHN51_RS15840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHN51_RS15845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHN51_RS15855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHN51_RS15865	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS15870	COG5001	Diguanylate cyclase
CHN51_RS15875	COG5001	Diguanylate cyclase
CHN51_RS15875	COG3300	MHYT domain
CHN51_RS15880	COG0360	Binds together with S18 to 16S ribosomal RNA
CHN51_RS15885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHN51_RS15890	COG0359	binds to the 23S rRNA
CHN51_RS15895	COG0302	gtp cyclohydrolase
CHN51_RS15905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHN51_RS15905	COG0574	Belongs to the PEP-utilizing enzyme family
CHN51_RS15910	COG0751	glycine-tRNA ligase activity
CHN51_RS15915	COG0752	glycyl-tRNA synthetase alpha subunit
CHN51_RS15920	COG0243	molybdopterin cofactor binding
CHN51_RS15940	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHN51_RS15945	COG0193	aminoacyl-tRNA hydrolase activity
CHN51_RS15950	COG0012	GTP binding
CHN51_RS15965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHN51_RS15975	COG1792	Involved in formation and maintenance of cell shape
CHN51_RS15990	COG0772	Belongs to the SEDS family
CHN51_RS16000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHN51_RS16005	COG1012	belongs to the aldehyde dehydrogenase family
CHN51_RS16015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CHN51_RS16020	COG0776	regulation of translation
CHN51_RS16030	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHN51_RS16060	COG2945	thiolester hydrolase activity
CHN51_RS16075	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CHN51_RS16080	COG0745	RESPONSE REGULATOR receiver
CHN51_RS16085	COG2205	protein histidine kinase activity
CHN51_RS16090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CHN51_RS16095	COG1660	Displays ATPase and GTPase activities
CHN51_RS16100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHN51_RS16100	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHN51_RS16110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHN51_RS16120	COG1322	Protein conserved in bacteria
CHN51_RS16125	COG0242	peptide deformylase activity
CHN51_RS16130	COG4771	TonB-dependent receptor
CHN51_RS16135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHN51_RS16140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHN51_RS16145	COG0101	tRNA pseudouridine synthase activity
CHN51_RS16150	COG0367	asparagine synthase
CHN51_RS16175	COG3409	Peptidoglycan-binding domain 1 protein
CHN51_RS16175	COG3267	Type II secretory pathway component ExeA
CHN51_RS16205	COG0318	PFAM AMP-dependent synthetase and ligase
CHN51_RS16230	COG0492	ferredoxin-NADP+ reductase activity
CHN51_RS16260	COG0678	peroxiredoxin activity
CHN51_RS16290	COG0277	FAD linked oxidase domain protein
CHN51_RS16310	COG2771	luxR family
CHN51_RS16330	COG4774	siderophore transport
CHN51_RS16330	COG1629	transport
CHN51_RS16350	COG2205	protein histidine kinase activity
CHN51_RS16355	COG1522	sequence-specific DNA binding
CHN51_RS16365	COG3022	response to hydroperoxide
CHN51_RS16370	COG0300	oxidoreductase activity
CHN51_RS16375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHN51_RS16390	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CHN51_RS16420	COG0022	dehydrogenase e1 component
CHN51_RS16420	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHN51_RS16425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHN51_RS16435	COG0148	phosphopyruvate hydratase activity
CHN51_RS16470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHN51_RS16495	COG0505	Belongs to the CarA family
CHN51_RS16510	COG0358	DNA primase activity
CHN51_RS16515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHN51_RS16525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHN51_RS16540	COG3876	Protein conserved in bacteria
CHN51_RS16550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHN51_RS16560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHN51_RS16570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHN51_RS16575	COG4251	negative regulation of phosphorylation
CHN51_RS16575	COG3706	GGDEF domain
CHN51_RS16575	COG5001	Diguanylate cyclase
CHN51_RS16575	COG2203	Gaf domain
CHN51_RS16580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHN51_RS16585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHN51_RS16595	COG3706	GGDEF domain
CHN51_RS16610	COG0653	protein targeting
CHN51_RS16620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHN51_RS16625	COG0483	inositol monophosphate 1-phosphatase activity
CHN51_RS16635	COG1074	ATP-dependent DNA helicase activity
CHN51_RS16640	COG2887	Belongs to the helicase family. UvrD subfamily
CHN51_RS16645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CHN51_RS16655	COG0802	atpase or kinase
CHN51_RS16660	COG2205	protein histidine kinase activity
CHN51_RS16665	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHN51_RS16685	COG0386	Belongs to the glutathione peroxidase family
CHN51_RS16690	COG1136	(ABC) transporter
CHN51_RS16700	COG0071	Belongs to the small heat shock protein (HSP20) family
CHN51_RS16710	COG0504	CTP synthase activity
CHN51_RS16720	COG0149	triose-phosphate isomerase activity
CHN51_RS16730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHN51_RS16755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHN51_RS16760	COG0134	indole-3-glycerol-phosphate synthase activity
CHN51_RS16765	COG0315	cyclic pyranopterin monophosphate synthase activity
CHN51_RS16770	COG0303	'Molybdopterin
CHN51_RS16795	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS16800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHN51_RS16805	COG0022	dehydrogenase e1 component
CHN51_RS16815	COG0095	Lipoate-protein ligase
CHN51_RS16830	COG0789	Transcriptional regulator
CHN51_RS16835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHN51_RS16840	COG0658	competence protein
CHN51_RS16840	COG2333	competence protein COMEC
CHN51_RS16845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHN51_RS16855	COG2205	protein histidine kinase activity
CHN51_RS16895	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CHN51_RS16905	COG1007	ATP synthesis coupled electron transport
CHN51_RS16920	COG0713	ATP synthesis coupled electron transport
CHN51_RS16935	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHN51_RS16945	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHN51_RS16955	COG1034	ATP synthesis coupled electron transport
CHN51_RS16970	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CHN51_RS16980	COG0649	NAD binding
CHN51_RS16985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHN51_RS16990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHN51_RS16995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHN51_RS17000	COG0483	inositol monophosphate 1-phosphatase activity
CHN51_RS17005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHN51_RS17015	COG0352	thiamine-phosphate diphosphorylase activity
CHN51_RS17020	COG4122	O-methyltransferase activity
CHN51_RS17025	COG3588	fructose-bisphosphate aldolase
CHN51_RS17030	COG0126	phosphoglycerate kinase activity
CHN51_RS17035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CHN51_RS17095	COG0022	dehydrogenase e1 component
CHN51_RS17105	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CHN51_RS17120	COG0784	Response regulator, receiver
CHN51_RS17120	COG2205	protein histidine kinase activity
CHN51_RS17120	COG2198	Histidine kinase
CHN51_RS17125	COG1024	Enoyl-CoA hydratase
CHN51_RS17130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHN51_RS17140	COG2267	carboxylic ester hydrolase activity
CHN51_RS17150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHN51_RS17165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHN51_RS17170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHN51_RS17175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHN51_RS17260	COG0187	DNA topoisomerase II activity
CHN51_RS17275	COG2967	ApaG domain
CHN51_RS17285	COG0473	3-isopropylmalate dehydrogenase activity
CHN51_RS17290	COG1381	Involved in DNA repair and RecF pathway recombination
CHN51_RS17305	COG0322	excinuclease ABC activity
CHN51_RS17310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHN51_RS17315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHN51_RS17320	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHN51_RS17325	COG0356	it plays a direct role in the translocation of protons across the membrane
CHN51_RS17335	COG0583	DNA-binding transcription factor activity
CHN51_RS17340	COG0778	Nitroreductase
CHN51_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS17350	COG0702	epimerase
CHN51_RS17370	COG2003	Belongs to the UPF0758 family
CHN51_RS17375	COG1028	Short-chain dehydrogenase reductase Sdr
CHN51_RS17380	COG0205	6-phosphofructokinase activity
CHN51_RS17385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHN51_RS17395	COG0284	orotidine-5'-phosphate decarboxylase activity
CHN51_RS17400	COG0135	phosphoribosylanthranilate isomerase activity
CHN51_RS17405	COG0133	tryptophan synthase activity
CHN51_RS17440	COG0159	tryptophan synthase activity
CHN51_RS17445	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHN51_RS17450	COG0285	dihydrofolate synthase activity
CHN51_RS17455	COG2223	nitrite transmembrane transporter activity
CHN51_RS17465	COG1187	pseudouridine synthase activity
CHN51_RS17470	COG0742	ribosomal rna small subunit methyltransferase
CHN51_RS17480	COG0210	DNA helicase
CHN51_RS17525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHN51_RS17545	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS17550	COG0789	Transcriptional regulator
CHN51_RS17560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHN51_RS17565	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHN51_RS17570	COG4221	oxidoreductase activity
CHN51_RS17580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHN51_RS17590	COG0415	Belongs to the DNA photolyase family
CHN51_RS17605	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHN51_RS17610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHN51_RS17610	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHN51_RS17615	COG0657	acetylesterase activity
CHN51_RS17620	COG1051	belongs to the nudix hydrolase family
CHN51_RS17635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHN51_RS17635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHN51_RS17655	COG0330	HflC and HflK could
CHN51_RS17680	COG1573	uracil-dna glycosylase
CHN51_RS17700	COG0069	glutamate synthase activity
CHN51_RS17715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHN51_RS17735	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHN51_RS17740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHN51_RS17745	COG0698	ribose 5-phosphate isomerase
CHN51_RS17750	COG3158	transport of potassium into the cell
CHN51_RS17760	COG3088	subunit of a heme lyase
CHN51_RS17770	COG1138	Cytochrome C-type biogenesis protein
CHN51_RS17775	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CHN51_RS17780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHN51_RS17785	COG0659	secondary active sulfate transmembrane transporter activity
CHN51_RS17845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CHN51_RS17850	COG1984	allophanate hydrolase subunit 2
CHN51_RS17855	COG0254	rRNA binding
CHN51_RS17860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHN51_RS17870	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHN51_RS17875	COG0750	zinc metalloprotease
CHN51_RS17880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHN51_RS17890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHN51_RS17895	COG0233	cytoplasmic translational termination
CHN51_RS17900	COG0528	UMP kinase activity
CHN51_RS17905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHN51_RS17910	COG0052	Belongs to the universal ribosomal protein uS2 family
CHN51_RS17915	COG2202	Pas domain
CHN51_RS17915	COG3920	Histidine kinase
CHN51_RS17925	COG1183	phosphatidylcholine synthase activity
CHN51_RS17930	COG0688	phosphatidylethanolamine metabolic process
CHN51_RS17935	COG0538	isocitrate dehydrogenase activity
CHN51_RS17940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHN51_RS17950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHN51_RS17960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHN51_RS17975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHN51_RS17980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHN51_RS17985	COG0741	lytic transglycosylase activity
CHN51_RS18010	COG2267	carboxylic ester hydrolase activity
CHN51_RS18015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHN51_RS18030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CHN51_RS18045	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CHN51_RS18050	COG0248	Ppx GppA phosphatase
CHN51_RS18055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHN51_RS18070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHN51_RS18075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHN51_RS18080	COG4566	intracellular signal transduction
CHN51_RS18100	COG2304	oxidoreductase activity
CHN51_RS18120	COG0105	UTP biosynthetic process
CHN51_RS18130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHN51_RS18135	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CHN51_RS18145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHN51_RS18150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHN51_RS18155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CHN51_RS18160	COG1473	amidohydrolase
CHN51_RS18170	COG3724	N-succinylarginine dihydrolase activity
CHN51_RS18195	COG1970	mechanosensitive ion channel activity
CHN51_RS18200	COG1704	LemA family
CHN51_RS18210	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CHN51_RS18230	COG0142	geranyltranstransferase activity
CHN51_RS18235	COG1605	Chorismate mutase
CHN51_RS18235	COG0287	Prephenate dehydrogenase
CHN51_RS18265	COG0488	(ABC) transporter
CHN51_RS18280	COG0438	transferase activity, transferring glycosyl groups
CHN51_RS18290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHN51_RS18300	COG1862	Preprotein translocase
CHN51_RS18340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHN51_RS18360	COG1414	Transcriptional regulator
CHN51_RS18365	COG0596	Alpha beta hydrolase
CHN51_RS18390	COG2146	nitrite reductase [NAD(P)H] activity
CHN51_RS18405	COG1802	Transcriptional regulator
CHN51_RS18425	COG2070	2-Nitropropane dioxygenase
CHN51_RS18455	COG3701	Conjugal transfer protein
CHN51_RS18475	COG3451	type IV secretory pathway VirB4
CHN51_RS18490	COG4962	Type ii secretion system protein e
CHN51_RS18515	COG0741	lytic transglycosylase activity
CHN51_RS18630	COG1192	Involved in chromosome partitioning
CHN51_RS18665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CHN51_RS18735	COG0741	lytic transglycosylase activity
CHN51_RS18765	COG0640	Transcriptional regulator
CHN51_RS18825	COG4974	Belongs to the 'phage' integrase family
CHN51_RS18835	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHN51_RS18845	COG0789	Transcriptional regulator
CHN51_RS18875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHN51_RS18895	COG0450	alkyl hydroperoxide reductase
CHN51_RS18900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHN51_RS18905	COG2132	Multicopper oxidase
CHN51_RS18935	COG1993	acr, cog1993
CHN51_RS18970	COG0671	phosphoesterase, PA-phosphatase related
CHN51_RS19000	COG1960	acyl-CoA dehydrogenase activity
CHN51_RS19025	COG2608	mercury ion transmembrane transporter activity
CHN51_RS19035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHN51_RS19065	COG3158	transport of potassium into the cell
CHN51_RS19080	COG4772	TonB-dependent receptor
CHN51_RS19100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHN51_RS19105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHN51_RS19105	COG0517	IMP dehydrogenase activity
CHN51_RS19110	COG2132	Multicopper oxidase
CHN51_RS19120	COG0789	Transcriptional regulator
CHN51_RS19145	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHN51_RS19170	COG2226	methyltransferase
CHN51_RS19175	COG2217	Heavy metal translocating P-type atpase
CHN51_RS19185	COG1937	Protein conserved in bacteria
CHN51_RS19225	COG2132	Multicopper oxidase
CHN51_RS19245	COG0672	)-iron permease
CHN51_RS19270	COG5642	Protein of unknown function (DUF2384)
CHN51_RS19285	COG3328	transposase activity
CHN51_RS19315	COG0420	3'-5' exonuclease activity
CHN51_RS19320	COG4717	serine-type aminopeptidase activity
CHN51_RS19340	COG3550	peptidyl-serine autophosphorylation
CHN51_RS19385	COG4774	siderophore transport
CHN51_RS19425	COG3547	Transposase (IS116 IS110 IS902 family)