locus-tag	class	description
GTU57_RS00060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GTU57_RS00075	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GTU57_RS00100	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GTU57_RS00115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GTU57_RS00240	COG0254	rRNA binding
GTU57_RS00480	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTU57_RS00695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GTU57_RS00710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GTU57_RS00715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GTU57_RS00760	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GTU57_RS01070	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GTU57_RS01080	COG0492	ferredoxin-NADP+ reductase activity
GTU57_RS01130	COG2827	Endonuclease containing a URI domain
GTU57_RS01170	COG0202	RNA polymerase activity
GTU57_RS01215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GTU57_RS01250	COG1192	Involved in chromosome partitioning
GTU57_RS01255	COG1475	DNA binding
GTU57_RS01430	COG1098	S1 RNA binding domain
GTU57_RS01440	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GTU57_RS01495	COG0359	binds to the 23S rRNA
GTU57_RS01520	COG0051	transcription antitermination factor activity, RNA binding
GTU57_RS01535	COG0089	rRNA binding
GTU57_RS01610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GTU57_RS01635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GTU57_RS01640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GTU57_RS01750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GTU57_RS01760	COG0335	large ribosomal subunit rRNA binding
GTU57_RS01775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GTU57_RS01985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GTU57_RS02090	COG0194	GDP metabolic process
GTU57_RS02165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTU57_RS02350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GTU57_RS02570	COG1077	Cell shape determining protein MreB Mrl
GTU57_RS02575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GTU57_RS02805	COG0813	purine-nucleoside phosphorylase activity
GTU57_RS02810	COG1428	Deoxynucleoside kinase
GTU57_RS02865	COG0539	negative regulation of cytoplasmic translation
GTU57_RS03060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GTU57_RS03065	COG0251	oxidation-reduction process
GTU57_RS03375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTU57_RS03750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GTU57_RS03770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GTU57_RS03950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GTU57_RS04035	COG1722	exodeoxyribonuclease VII activity
GTU57_RS04470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GTU57_RS04875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GTU57_RS05115	COG0124	histidyl-tRNA synthetase
GTU57_RS05580	COG0564	pseudouridine synthase activity
GTU57_RS05630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GTU57_RS06675	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GTU57_RS07255	COG3599	regulation of cell shape
GTU57_RS07270	COG0776	regulation of translation
GTU57_RS07360	COG0237	dephospho-CoA kinase activity
GTU57_RS07530	COG0180	Tryptophanyl-tRNA synthetase
GTU57_RS07875	COG1105	Belongs to the carbohydrate kinase PfkB family
GTU57_RS08170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GTU57_RS08405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GTU57_RS08705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GTU57_RS08800	COG0569	domain protein
GTU57_RS08870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GTU57_RS09020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GTU57_RS09030	COG0822	iron-sulfur transferase activity
GTU57_RS09090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GTU57_RS09365	COG0222	ribosome binding
GTU57_RS09370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GTU57_RS09460	COG1077	Cell shape determining protein MreB Mrl
GTU57_RS09525	COG0594	ribonuclease P activity
GTU57_RS09535	COG0517	IMP dehydrogenase activity
GTU57_RS09535	COG0516	GMP reductase activity
