locus-tag	class	description
HHA36_RS00060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HHA36_RS00075	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHA36_RS00100	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HHA36_RS00115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHA36_RS00155	COG0254	rRNA binding
HHA36_RS00415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HHA36_RS00495	COG0508	dehydrogenase complex catalyzes the overall conversion of
HHA36_RS00715	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHA36_RS00730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHA36_RS00735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HHA36_RS00780	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHA36_RS01085	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHA36_RS01145	COG2827	Endonuclease containing a URI domain
HHA36_RS01185	COG0202	RNA polymerase activity
HHA36_RS01230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HHA36_RS01265	COG1192	Involved in chromosome partitioning
HHA36_RS01270	COG1475	DNA binding
HHA36_RS01460	COG1098	S1 RNA binding domain
HHA36_RS01470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHA36_RS01525	COG0359	binds to the 23S rRNA
HHA36_RS01550	COG0051	transcription antitermination factor activity, RNA binding
HHA36_RS01565	COG0089	rRNA binding
HHA36_RS01640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHA36_RS01665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HHA36_RS01670	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHA36_RS01680	COG0202	RNA polymerase activity
HHA36_RS01780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHA36_RS01790	COG0335	large ribosomal subunit rRNA binding
HHA36_RS01805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHA36_RS02010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HHA36_RS02185	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HHA36_RS02365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHA36_RS02545	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HHA36_RS02750	COG1077	Cell shape determining protein MreB Mrl
HHA36_RS02755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HHA36_RS02990	COG0813	purine-nucleoside phosphorylase activity
HHA36_RS02995	COG1428	Deoxynucleoside kinase
HHA36_RS03050	COG0539	negative regulation of cytoplasmic translation
HHA36_RS03245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHA36_RS03250	COG0251	oxidation-reduction process
HHA36_RS03325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HHA36_RS03670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHA36_RS03690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHA36_RS03970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHA36_RS04050	COG1722	exodeoxyribonuclease VII activity
HHA36_RS04325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHA36_RS04880	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HHA36_RS05110	COG0124	histidyl-tRNA synthetase
HHA36_RS05235	COG0539	negative regulation of cytoplasmic translation
HHA36_RS05725	COG1098	S1 RNA binding domain
HHA36_RS06040	COG0564	pseudouridine synthase activity
HHA36_RS06090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HHA36_RS06885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHA36_RS07490	COG3599	regulation of cell shape
HHA36_RS07505	COG0776	regulation of translation
HHA36_RS07590	COG0237	dephospho-CoA kinase activity
HHA36_RS07755	COG0180	Tryptophanyl-tRNA synthetase
HHA36_RS08095	COG1105	Belongs to the carbohydrate kinase PfkB family
HHA36_RS08385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHA36_RS08620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHA36_RS08920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHA36_RS09020	COG0569	domain protein
HHA36_RS09150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHA36_RS09160	COG0822	iron-sulfur transferase activity
HHA36_RS09220	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HHA36_RS09415	COG0222	ribosome binding
HHA36_RS09420	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHA36_RS09485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HHA36_RS09575	COG0594	ribonuclease P activity
HHA36_RS09585	COG0517	IMP dehydrogenase activity
HHA36_RS09585	COG0516	GMP reductase activity