locus-tag	class	description
CWM47_RS00030	COG0183	Belongs to the thiolase family
CWM47_RS00035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CWM47_RS00045	COG1234	tRNA 3'-trailer cleavage
CWM47_RS00050	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CWM47_RS00070	COG0579	oxidoreductase
CWM47_RS00075	COG3386	PFAM SMP-30 Gluconolaconase
CWM47_RS00095	COG1609	Transcriptional regulator
CWM47_RS00115	COG2814	Major facilitator Superfamily
CWM47_RS00135	COG3384	dioxygenase
CWM47_RS00165	COG0363	glucosamine-6-phosphate deaminase activity
CWM47_RS00170	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS00175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CWM47_RS00180	COG0698	ribose 5-phosphate isomerase
CWM47_RS00185	COG1132	(ABC) transporter
CWM47_RS00195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWM47_RS00195	COG1199	ATP-dependent helicase activity
CWM47_RS00210	COG2353	YceI-like domain
CWM47_RS00265	COG0825	malonyl-CoA metabolic process
CWM47_RS00270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CWM47_RS00275	COG2027	D-alanyl-D-alanine carboxypeptidase
CWM47_RS00280	COG0784	Response regulator, receiver
CWM47_RS00285	COG4251	negative regulation of phosphorylation
CWM47_RS00290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CWM47_RS00295	COG1522	sequence-specific DNA binding
CWM47_RS00300	COG0481	GTPase activity
CWM47_RS00310	COG2382	esterase
CWM47_RS00325	COG1064	alcohol dehydrogenase
CWM47_RS00330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWM47_RS00335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CWM47_RS00340	COG2080	2 iron, 2 sulfur cluster binding
CWM47_RS00360	COG1764	response to oxidative stress
CWM47_RS00375	COG4771	TonB-dependent receptor
CWM47_RS00410	COG2885	chlorophyll binding
CWM47_RS00420	COG1760	l-serine dehydratase
CWM47_RS00435	COG1695	Transcriptional regulator
CWM47_RS00445	COG4251	negative regulation of phosphorylation
CWM47_RS00460	COG4251	negative regulation of phosphorylation
CWM47_RS00485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CWM47_RS00515	COG0784	Response regulator, receiver
CWM47_RS00515	COG2205	protein histidine kinase activity
CWM47_RS00520	COG5002	protein histidine kinase activity
CWM47_RS00540	COG3685	Protein conserved in bacteria
CWM47_RS00550	COG1335	isochorismatase
CWM47_RS00570	COG2205	protein histidine kinase activity
CWM47_RS00570	COG0745	RESPONSE REGULATOR receiver
CWM47_RS00570	COG3292	Two component regulator propeller
CWM47_RS00575	COG2205	protein histidine kinase activity
CWM47_RS00590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWM47_RS00620	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CWM47_RS00630	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CWM47_RS00635	COG1454	alcohol dehydrogenase
CWM47_RS00650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWM47_RS00655	COG0590	tRNA wobble adenosine to inosine editing
CWM47_RS00670	COG0746	molybdenum cofactor guanylyltransferase activity
CWM47_RS00670	COG0315	cyclic pyranopterin monophosphate synthase activity
CWM47_RS00675	COG0746	molybdenum cofactor guanylyltransferase activity
CWM47_RS00675	COG0315	cyclic pyranopterin monophosphate synthase activity
CWM47_RS00680	COG0303	'Molybdopterin
CWM47_RS00715	COG1796	DNA polymerase
CWM47_RS00715	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CWM47_RS00725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CWM47_RS00745	COG1902	pentaerythritol trinitrate reductase activity
CWM47_RS00750	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS00755	COG0673	inositol 2-dehydrogenase activity
CWM47_RS00775	COG4771	TonB-dependent receptor
CWM47_RS00800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWM47_RS00805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWM47_RS00810	COG0456	acetyltransferase
CWM47_RS00825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWM47_RS00885	COG0823	Involved in the tonB-independent uptake of proteins
CWM47_RS00895	COG2382	esterase
CWM47_RS00900	COG0519	Catalyzes the synthesis of GMP from XMP
CWM47_RS00900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CWM47_RS00920	COG1216	Glycosyl transferase, family 2
CWM47_RS00920	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS00945	COG2244	polysaccharide biosynthetic process
CWM47_RS00975	COG3507	Belongs to the glycosyl hydrolase 43 family
CWM47_RS01005	COG0564	pseudouridine synthase activity
CWM47_RS01040	COG2223	nitrite transmembrane transporter activity
CWM47_RS01045	COG0288	reversible hydration of carbon dioxide
CWM47_RS01055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWM47_RS01075	COG4251	negative regulation of phosphorylation
CWM47_RS01080	COG0366	Alpha amylase catalytic
CWM47_RS01120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWM47_RS01135	COG0321	lipoyl(octanoyl) transferase activity
CWM47_RS01135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CWM47_RS01145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CWM47_RS01160	COG1132	(ABC) transporter
CWM47_RS01215	COG1629	transport
CWM47_RS01215	COG4206	TonB-dependent receptor
CWM47_RS01240	COG1785	Belongs to the alkaline phosphatase family
CWM47_RS01240	COG1785	Belongs to the alkaline phosphatase family
CWM47_RS01250	COG0702	epimerase
CWM47_RS01255	COG4771	TonB-dependent receptor
CWM47_RS01275	COG3158	transport of potassium into the cell
CWM47_RS01285	COG2205	protein histidine kinase activity
CWM47_RS01285	COG5002	protein histidine kinase activity
CWM47_RS01285	COG0784	Response regulator, receiver
CWM47_RS01330	COG1247	-acetyltransferase
CWM47_RS01335	COG2239	Acts as a magnesium transporter
CWM47_RS01340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CWM47_RS01345	COG2852	Protein conserved in bacteria
CWM47_RS01405	COG5002	protein histidine kinase activity
CWM47_RS01405	COG2205	protein histidine kinase activity
CWM47_RS01405	COG0784	Response regulator, receiver
CWM47_RS01415	COG2321	neutral zinc metallopeptidase
CWM47_RS01420	COG1902	pentaerythritol trinitrate reductase activity
CWM47_RS01435	COG2267	carboxylic ester hydrolase activity
CWM47_RS01450	COG3228	Belongs to the MtfA family
CWM47_RS01465	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWM47_RS01485	COG1228	amidohydrolase
CWM47_RS01530	COG1136	(ABC) transporter
CWM47_RS01530	COG0577	efflux transmembrane transporter activity
CWM47_RS01535	COG0577	efflux transmembrane transporter activity
CWM47_RS01575	COG1136	(ABC) transporter
CWM47_RS01575	COG0577	efflux transmembrane transporter activity
CWM47_RS01585	COG0577	efflux transmembrane transporter activity
CWM47_RS01600	COG0577	efflux transmembrane transporter activity
CWM47_RS01600	COG1136	(ABC) transporter
CWM47_RS01625	COG3876	Protein conserved in bacteria
CWM47_RS01630	COG0482	sulfurtransferase activity
CWM47_RS01645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWM47_RS01670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWM47_RS01675	COG0714	Associated with various cellular activities
CWM47_RS01680	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CWM47_RS01720	COG0590	tRNA wobble adenosine to inosine editing
CWM47_RS01735	COG0577	efflux transmembrane transporter activity
CWM47_RS01745	COG2205	protein histidine kinase activity
CWM47_RS01745	COG0784	Response regulator, receiver
CWM47_RS01755	COG2081	HI0933 family
CWM47_RS01760	COG0196	riboflavin kinase activity
CWM47_RS01765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CWM47_RS01770	COG1968	undecaprenyl-diphosphatase activity
CWM47_RS01780	COG2177	Part of the ABC transporter FtsEX involved in
CWM47_RS01785	COG0101	tRNA pseudouridine synthase activity
CWM47_RS01795	COG0668	transmembrane transport
CWM47_RS01825	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CWM47_RS01835	COG0823	Involved in the tonB-independent uptake of proteins
CWM47_RS01835	COG1506	peptidase
CWM47_RS01890	COG3852	Histidine kinase
CWM47_RS01895	COG0784	Response regulator, receiver
CWM47_RS01905	COG2204	response regulator
CWM47_RS01910	COG0745	RESPONSE REGULATOR receiver
CWM47_RS01935	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CWM47_RS01940	COG1228	amidohydrolase
CWM47_RS01945	COG1629	transport
CWM47_RS01945	COG4206	TonB-dependent receptor
CWM47_RS01960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CWM47_RS01970	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CWM47_RS02005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWM47_RS02030	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS02035	COG0302	gtp cyclohydrolase
CWM47_RS02050	COG0673	inositol 2-dehydrogenase activity
CWM47_RS02065	COG4591	ABC-type transport system involved in lipoprotein release permease component
CWM47_RS02070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CWM47_RS02085	COG1858	cytochrome C peroxidase
CWM47_RS02090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWM47_RS02100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CWM47_RS02105	COG3604	Transcriptional regulator
CWM47_RS02130	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CWM47_RS02135	COG0459	protein refolding
CWM47_RS02145	COG1136	(ABC) transporter
CWM47_RS02150	COG0045	succinate-CoA ligase (ADP-forming) activity
CWM47_RS02160	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWM47_RS02170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CWM47_RS02175	COG3959	Transketolase, thiamine diphosphate binding domain
CWM47_RS02180	COG1196	nuclear chromosome segregation
CWM47_RS02190	COG3958	Transketolase
CWM47_RS02195	COG1595	DNA-templated transcription, initiation
CWM47_RS02215	COG3757	hydrolase, family 25
CWM47_RS02225	COG0450	alkyl hydroperoxide reductase
CWM47_RS02235	COG4585	Histidine kinase
CWM47_RS02255	COG0791	NLP P60 protein
CWM47_RS02265	COG1278	Cold shock
CWM47_RS02280	COG0617	tRNA 3'-terminal CCA addition
CWM47_RS02290	COG0628	permease
CWM47_RS02300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CWM47_RS02315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CWM47_RS02325	COG2267	carboxylic ester hydrolase activity
CWM47_RS02355	COG0583	DNA-binding transcription factor activity
CWM47_RS02360	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CWM47_RS02370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWM47_RS02375	COG0450	alkyl hydroperoxide reductase
CWM47_RS02405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CWM47_RS02405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWM47_RS02425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CWM47_RS02430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CWM47_RS02440	COG1024	Enoyl-CoA hydratase
CWM47_RS02465	COG1733	regulation of RNA biosynthetic process
CWM47_RS02470	COG1733	regulation of RNA biosynthetic process
CWM47_RS02535	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS02560	COG2972	Histidine kinase
CWM47_RS02560	COG0745	RESPONSE REGULATOR receiver
CWM47_RS02565	COG3279	Response regulator of the LytR AlgR family
CWM47_RS02575	COG2801	Transposase and inactivated derivatives
CWM47_RS02605	COG2226	methyltransferase
CWM47_RS02605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWM47_RS02605	COG0596	Alpha beta hydrolase
CWM47_RS02615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CWM47_RS02630	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS02665	COG2072	flavoprotein involved in K transport
CWM47_RS02685	COG2801	Transposase and inactivated derivatives
CWM47_RS02690	COG1408	metallophosphoesterase
CWM47_RS02715	COG0673	inositol 2-dehydrogenase activity
CWM47_RS02720	COG0673	inositol 2-dehydrogenase activity
CWM47_RS02730	COG0445	tRNA wobble uridine modification
CWM47_RS02740	COG4821	SIS domain
CWM47_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS02755	COG2188	Transcriptional regulator
CWM47_RS02760	COG0702	epimerase
CWM47_RS02765	COG4771	TonB-dependent receptor
CWM47_RS02790	COG0823	Involved in the tonB-independent uptake of proteins
CWM47_RS02790	COG1506	peptidase
CWM47_RS02795	COG1733	regulation of RNA biosynthetic process
CWM47_RS02875	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CWM47_RS02895	COG0126	phosphoglycerate kinase activity
CWM47_RS02905	COG1959	2 iron, 2 sulfur cluster binding
CWM47_RS02940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWM47_RS02990	COG1803	Methylglyoxal synthase
CWM47_RS02990	COG1597	lipid kinase activity
CWM47_RS02995	COG0494	nUDIX hydrolase
CWM47_RS03080	COG1196	nuclear chromosome segregation
CWM47_RS03085	COG0326	Molecular chaperone. Has ATPase activity
CWM47_RS03165	COG2353	YceI-like domain
CWM47_RS03175	COG3275	phosphorelay sensor kinase activity
CWM47_RS03185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWM47_RS03190	COG4628	conserved protein (DUF2132)
CWM47_RS03200	COG1929	Belongs to the glycerate kinase type-1 family
CWM47_RS03205	COG0673	inositol 2-dehydrogenase activity
CWM47_RS03210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CWM47_RS03230	COG0423	glycine-tRNA ligase activity
CWM47_RS03235	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWM47_RS03255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWM47_RS03265	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS03495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWM47_RS03515	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CWM47_RS03535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWM47_RS03555	COG0776	regulation of translation
CWM47_RS03695	COG1629	transport
CWM47_RS03770	COG1082	Xylose isomerase domain protein TIM barrel
CWM47_RS03805	COG0745	RESPONSE REGULATOR receiver
CWM47_RS03810	COG5002	protein histidine kinase activity
CWM47_RS03815	COG0745	RESPONSE REGULATOR receiver
CWM47_RS03820	COG2205	protein histidine kinase activity
CWM47_RS03820	COG0784	Response regulator, receiver
CWM47_RS03825	COG0339	signal peptide processing
CWM47_RS03835	COG3781	membrane
CWM47_RS03840	COG1301	dicarboxylic acid transport
CWM47_RS03860	COG3237	CsbD-like
CWM47_RS03885	COG1136	(ABC) transporter
CWM47_RS03885	COG0577	efflux transmembrane transporter activity
CWM47_RS03890	COG1136	(ABC) transporter
CWM47_RS03900	COG3279	Response regulator of the LytR AlgR family
CWM47_RS03905	COG0612	Peptidase, M16
CWM47_RS03915	COG0697	spore germination
CWM47_RS03930	COG0129	dihydroxy-acid dehydratase activity
CWM47_RS03935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWM47_RS03950	COG0739	heme binding
CWM47_RS03950	COG0741	lytic transglycosylase activity
CWM47_RS03950	COG1196	nuclear chromosome segregation
CWM47_RS03960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWM47_RS03965	COG1127	ABC transporter
CWM47_RS03980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWM47_RS03990	COG1045	serine acetyltransferase
CWM47_RS04000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWM47_RS04010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWM47_RS04020	COG1940	carbohydrate kinase activity
CWM47_RS04050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CWM47_RS04070	COG0484	heat shock protein binding
CWM47_RS04075	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CWM47_RS04080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CWM47_RS04085	COG3844	kynureninase activity
CWM47_RS04240	COG3501	Rhs element vgr protein
CWM47_RS04260	COG4206	TonB-dependent receptor
CWM47_RS04260	COG1629	transport
CWM47_RS04275	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS04280	COG1024	Enoyl-CoA hydratase
CWM47_RS04295	COG0626	cystathionine gamma-synthase activity
CWM47_RS04305	COG0346	lactoylglutathione lyase activity
CWM47_RS04315	COG0668	transmembrane transport
CWM47_RS04355	COG0784	Response regulator, receiver
CWM47_RS04355	COG2205	protein histidine kinase activity
CWM47_RS04360	COG2340	Cysteine-rich secretory protein family
CWM47_RS04380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CWM47_RS04395	COG0667	Aldo Keto reductase
CWM47_RS04480	COG3275	phosphorelay sensor kinase activity
CWM47_RS04485	COG3279	Response regulator of the LytR AlgR family
CWM47_RS04505	COG1252	NADH dehydrogenase
CWM47_RS04510	COG4221	oxidoreductase activity
CWM47_RS04535	COG3920	Histidine kinase
CWM47_RS04540	COG3920	Histidine kinase
CWM47_RS04585	COG2329	Antibiotic biosynthesis monooxygenase
CWM47_RS04610	COG4771	TonB-dependent receptor
CWM47_RS04620	COG0745	RESPONSE REGULATOR receiver
CWM47_RS04625	COG5002	protein histidine kinase activity
CWM47_RS04635	COG0659	secondary active sulfate transmembrane transporter activity
CWM47_RS04640	COG0784	Response regulator, receiver
CWM47_RS04640	COG2198	Histidine kinase
CWM47_RS04640	COG0643	Histidine kinase
CWM47_RS04645	COG2819	hydrolase of the alpha beta superfamily
CWM47_RS04650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CWM47_RS04670	COG1943	Transposase
CWM47_RS04690	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS04700	COG0460	homoserine dehydrogenase
CWM47_RS04700	COG0527	aspartate kinase activity
CWM47_RS04710	COG1401	restriction endodeoxyribonuclease activity
CWM47_RS04730	COG0673	inositol 2-dehydrogenase activity
CWM47_RS04740	COG1629	transport
CWM47_RS04755	COG0632	four-way junction helicase activity
CWM47_RS04765	COG1388	LysM domain
CWM47_RS04765	COG0791	NLP P60 protein
CWM47_RS04770	COG0154	amidase activity
CWM47_RS04775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWM47_RS04785	COG0039	L-malate dehydrogenase activity
CWM47_RS04805	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CWM47_RS04805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWM47_RS04815	COG3590	peptidase
CWM47_RS04860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CWM47_RS04865	COG0081	regulation of translation
CWM47_RS04870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CWM47_RS04875	COG0222	ribosome binding
CWM47_RS04880	COG0085	RNA polymerase activity
CWM47_RS04885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CWM47_RS04905	COG4771	TonB-dependent receptor
CWM47_RS04915	COG0154	amidase activity
CWM47_RS04960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CWM47_RS04965	COG1104	cysteine desulfurase activity
CWM47_RS04970	COG1032	radical SAM domain protein
CWM47_RS04980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CWM47_RS04985	COG0297	glycogen (starch) synthase activity
CWM47_RS04990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CWM47_RS05000	COG0700	Nucleoside recognition
CWM47_RS05020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CWM47_RS05055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CWM47_RS05060	COG0049	tRNA binding
CWM47_RS05095	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CWM47_RS05100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWM47_RS05105	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CWM47_RS05120	COG0275	rRNA processing
CWM47_RS05140	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWM47_RS05140	COG1024	Enoyl-CoA hydratase
CWM47_RS05150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWM47_RS05155	COG1187	pseudouridine synthase activity
CWM47_RS05160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CWM47_RS05170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CWM47_RS05175	COG2045	Belongs to the ComB family
CWM47_RS05195	COG2814	Major facilitator Superfamily
CWM47_RS05200	COG1566	PFAM secretion protein HlyD family protein
CWM47_RS05210	COG1012	belongs to the aldehyde dehydrogenase family
CWM47_RS05215	COG0586	Pfam SNARE associated Golgi protein
CWM47_RS05220	COG0488	(ABC) transporter
CWM47_RS05225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWM47_RS05225	COG0515	serine threonine protein kinase
CWM47_RS05235	COG0436	Aminotransferase
CWM47_RS05255	COG0564	pseudouridine synthase activity
CWM47_RS05260	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CWM47_RS05280	COG1764	response to oxidative stress
CWM47_RS05290	COG0793	Belongs to the peptidase S41A family
CWM47_RS05300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CWM47_RS05315	COG1024	Enoyl-CoA hydratase
CWM47_RS05325	COG2115	Belongs to the xylose isomerase family
CWM47_RS05335	COG0737	Belongs to the 5'-nucleotidase family
CWM47_RS05350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CWM47_RS05360	COG0456	acetyltransferase
CWM47_RS05375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CWM47_RS05385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWM47_RS05405	COG3292	Two component regulator propeller
CWM47_RS05405	COG2205	protein histidine kinase activity
CWM47_RS05405	COG0745	RESPONSE REGULATOR receiver
CWM47_RS05415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWM47_RS05430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CWM47_RS05500	COG2169	Transcriptional regulator
CWM47_RS05505	COG2272	Belongs to the type-B carboxylesterase lipase family
CWM47_RS05510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWM47_RS05515	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CWM47_RS05520	COG2080	2 iron, 2 sulfur cluster binding
CWM47_RS05550	COG1794	racemase activity, acting on amino acids and derivatives
CWM47_RS05565	COG1090	epimerase
CWM47_RS05600	COG1629	transport
CWM47_RS05615	COG2755	lipolytic protein G-D-S-L family
CWM47_RS05630	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CWM47_RS05660	COG4771	TonB-dependent receptor
CWM47_RS05665	COG0702	epimerase
CWM47_RS05675	COG0488	(ABC) transporter
CWM47_RS05685	COG3781	membrane
CWM47_RS05695	COG0012	GTP binding
CWM47_RS05720	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CWM47_RS05725	COG0205	6-phosphofructokinase activity
CWM47_RS05735	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS05755	COG2089	acid synthase
CWM47_RS05770	COG1083	cytidylyl-transferase
CWM47_RS05775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWM47_RS05795	COG1086	Polysaccharide biosynthesis protein
CWM47_RS05800	COG3119	arylsulfatase activity
CWM47_RS05810	COG2205	protein histidine kinase activity
CWM47_RS05810	COG0784	Response regulator, receiver
CWM47_RS05840	COG3292	Two component regulator propeller
CWM47_RS05840	COG0745	RESPONSE REGULATOR receiver
CWM47_RS05840	COG2205	protein histidine kinase activity
CWM47_RS05860	COG0248	Ppx GppA phosphatase
CWM47_RS05870	COG2192	nodulation
CWM47_RS05885	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CWM47_RS05900	COG1070	Carbohydrate kinase
CWM47_RS05930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWM47_RS05935	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CWM47_RS05940	COG2080	2 iron, 2 sulfur cluster binding
CWM47_RS05970	COG0415	Belongs to the DNA photolyase family
CWM47_RS06005	COG2304	oxidoreductase activity
CWM47_RS06015	COG4682	membrane
CWM47_RS06020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWM47_RS06020	COG1017	nitric oxide dioxygenase activity
CWM47_RS06045	COG3279	Response regulator of the LytR AlgR family
CWM47_RS06050	COG2972	Histidine kinase
CWM47_RS06070	COG0745	RESPONSE REGULATOR receiver
CWM47_RS06070	COG2205	protein histidine kinase activity
CWM47_RS06070	COG3292	Two component regulator propeller
CWM47_RS06085	COG2207	Transcriptional regulator
CWM47_RS06085	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS06090	COG0457	Tetratricopeptide repeat
CWM47_RS06105	COG2814	Major facilitator Superfamily
CWM47_RS06110	COG4771	TonB-dependent receptor
CWM47_RS06145	COG3292	Two component regulator propeller
CWM47_RS06145	COG2205	protein histidine kinase activity
CWM47_RS06145	COG3292	Two component regulator propeller
CWM47_RS06145	COG0745	RESPONSE REGULATOR receiver
CWM47_RS06145	COG0745	RESPONSE REGULATOR receiver
CWM47_RS06145	COG2205	protein histidine kinase activity
CWM47_RS06185	COG1462	curli production assembly transport component CsgG
CWM47_RS06260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWM47_RS06320	COG2814	Major facilitator Superfamily
CWM47_RS06325	COG1473	amidohydrolase
CWM47_RS06330	COG5183	chlorophyll binding
CWM47_RS06330	COG2133	pyrroloquinoline quinone binding
CWM47_RS06335	COG3291	Pkd domain containing protein
CWM47_RS06340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CWM47_RS06360	COG0492	ferredoxin-NADP+ reductase activity
CWM47_RS06370	COG1506	peptidase
CWM47_RS06370	COG0823	Involved in the tonB-independent uptake of proteins
CWM47_RS06370	COG4946	Tricorn protease homolog
CWM47_RS06375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWM47_RS06385	COG1473	amidohydrolase
CWM47_RS06405	COG0251	oxidation-reduction process
CWM47_RS06435	COG2323	membrane
CWM47_RS06450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CWM47_RS06470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWM47_RS06490	COG0322	excinuclease ABC activity
CWM47_RS06520	COG0356	it plays a direct role in the translocation of protons across the membrane
CWM47_RS06525	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWM47_RS06530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CWM47_RS06535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWM47_RS06555	COG0702	epimerase
CWM47_RS06560	COG1629	transport
CWM47_RS06560	COG4206	TonB-dependent receptor
CWM47_RS06565	COG0673	inositol 2-dehydrogenase activity
CWM47_RS06570	COG3386	PFAM SMP-30 Gluconolaconase
CWM47_RS06580	COG0772	Belongs to the SEDS family
CWM47_RS06590	COG0745	RESPONSE REGULATOR receiver
CWM47_RS06590	COG3292	Two component regulator propeller
CWM47_RS06590	COG2205	protein histidine kinase activity
CWM47_RS06600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWM47_RS06605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWM47_RS06610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CWM47_RS06615	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS06635	COG2814	Major facilitator Superfamily
CWM47_RS06640	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWM47_RS06640	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CWM47_RS06645	COG1621	beta-fructofuranosidase activity
CWM47_RS06670	COG4251	negative regulation of phosphorylation
CWM47_RS06725	COG2755	lipolytic protein G-D-S-L family
CWM47_RS06765	COG2160	L-arabinose isomerase activity
CWM47_RS06780	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CWM47_RS06785	COG2271	Major facilitator Superfamily
CWM47_RS06800	COG0246	Mannitol dehydrogenase
CWM47_RS06805	COG1609	Transcriptional regulator
CWM47_RS06810	COG0640	Transcriptional regulator
CWM47_RS06825	COG2382	esterase
CWM47_RS06845	COG1063	alcohol dehydrogenase
CWM47_RS06890	COG0772	Belongs to the SEDS family
CWM47_RS06900	COG0515	serine threonine protein kinase
CWM47_RS06930	COG2378	regulation of single-species biofilm formation
CWM47_RS06945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CWM47_RS06955	COG0745	RESPONSE REGULATOR receiver
CWM47_RS06975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CWM47_RS06980	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CWM47_RS07000	COG1999	signal sequence binding
CWM47_RS07010	COG0497	DNA recombination
CWM47_RS07045	COG0037	tRNA processing
CWM47_RS07050	COG2885	chlorophyll binding
CWM47_RS07080	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CWM47_RS07120	COG0714	Associated with various cellular activities
CWM47_RS07200	COG2954	triphosphatase activity
CWM47_RS07245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CWM47_RS07255	COG0004	ammonium transporteR
CWM47_RS07270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CWM47_RS07275	COG2382	esterase
CWM47_RS07275	COG3693	PFAM glycoside hydrolase, family 10
CWM47_RS07295	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CWM47_RS07300	COG3590	peptidase
CWM47_RS07320	COG2197	response regulator
CWM47_RS07330	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWM47_RS07335	COG1546	Belongs to the CinA family
CWM47_RS07335	COG1058	Belongs to the CinA family
CWM47_RS07355	COG4771	TonB-dependent receptor
CWM47_RS07405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CWM47_RS07430	COG0542	response to heat
CWM47_RS07445	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS07455	COG4993	Dehydrogenase
CWM47_RS07460	COG0513	Belongs to the DEAD box helicase family
CWM47_RS07465	COG4221	oxidoreductase activity
CWM47_RS07485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CWM47_RS07490	COG0017	Asparaginyl-tRNA synthetase
CWM47_RS07505	COG0346	lactoylglutathione lyase activity
CWM47_RS07525	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CWM47_RS07535	COG2095	MarC family integral membrane protein
CWM47_RS07540	COG0174	glutamine synthetase
CWM47_RS07570	COG2195	Cleaves the N-terminal amino acid of tripeptides
CWM47_RS07575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWM47_RS07580	COG3341	Caulimovirus viroplasmin
CWM47_RS07580	COG0328	RNA-DNA hybrid ribonuclease activity
CWM47_RS07585	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CWM47_RS07590	COG0463	Glycosyl transferase, family 2
CWM47_RS07595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CWM47_RS07600	COG0616	signal peptide processing
CWM47_RS07605	COG2207	Transcriptional regulator
CWM47_RS07615	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CWM47_RS07630	COG2072	flavoprotein involved in K transport
CWM47_RS07635	COG0463	Glycosyl transferase, family 2
CWM47_RS07665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWM47_RS07670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CWM47_RS07680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWM47_RS07710	COG3685	Protein conserved in bacteria
CWM47_RS07725	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS07730	COG0123	including yeast histone deacetylase and acetoin utilization protein
CWM47_RS07740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CWM47_RS07745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CWM47_RS07760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWM47_RS07765	COG4206	TonB-dependent receptor
CWM47_RS07765	COG1629	transport
CWM47_RS07775	COG1629	transport
CWM47_RS07775	COG4206	TonB-dependent receptor
CWM47_RS07795	COG2610	gluconate transmembrane transporter activity
CWM47_RS07805	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CWM47_RS07820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CWM47_RS07830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWM47_RS07845	COG4702	Belongs to the UPF0303 family
CWM47_RS07850	COG0604	alcohol dehydrogenase
CWM47_RS07860	COG3537	Alpha-1,2-mannosidase
CWM47_RS07865	COG2130	NADP-dependent
CWM47_RS07870	COG1764	response to oxidative stress
CWM47_RS07875	COG1846	Transcriptional regulator
CWM47_RS07890	COG1136	(ABC) transporter
CWM47_RS07895	COG0577	efflux transmembrane transporter activity
CWM47_RS07895	COG1136	(ABC) transporter
CWM47_RS07900	COG0577	efflux transmembrane transporter activity
CWM47_RS07900	COG1136	(ABC) transporter
CWM47_RS07905	COG2204	response regulator
CWM47_RS07910	COG4191	Histidine kinase
CWM47_RS07940	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CWM47_RS07965	COG1012	belongs to the aldehyde dehydrogenase family
CWM47_RS07970	COG2207	Transcriptional regulator
CWM47_RS08000	COG0067	glutamate synthase
CWM47_RS08000	COG0069	glutamate synthase activity
CWM47_RS08000	COG0070	glutamate synthase
CWM47_RS08015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CWM47_RS08045	COG0442	prolyl-tRNA aminoacylation
CWM47_RS08065	COG1047	Peptidyl-prolyl cis-trans
CWM47_RS08100	COG0745	RESPONSE REGULATOR receiver
CWM47_RS08115	COG5002	protein histidine kinase activity
CWM47_RS08125	COG0640	Transcriptional regulator
CWM47_RS08160	COG0408	coproporphyrinogen oxidase activity
CWM47_RS08175	COG0784	Response regulator, receiver
CWM47_RS08180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWM47_RS08210	COG0596	Alpha beta hydrolase
CWM47_RS08210	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWM47_RS08230	COG0596	Alpha beta hydrolase
CWM47_RS08240	COG1063	alcohol dehydrogenase
CWM47_RS08245	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS08255	COG1278	Cold shock
CWM47_RS08265	COG0561	phosphatase activity
CWM47_RS08280	COG5002	protein histidine kinase activity
CWM47_RS08280	COG0784	Response regulator, receiver
CWM47_RS08305	COG0577	efflux transmembrane transporter activity
CWM47_RS08305	COG1136	(ABC) transporter
CWM47_RS08330	COG2267	carboxylic ester hydrolase activity
CWM47_RS08355	COG0564	pseudouridine synthase activity
CWM47_RS08360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWM47_RS08385	COG0702	epimerase
CWM47_RS08390	COG4771	TonB-dependent receptor
CWM47_RS08395	COG0702	epimerase
CWM47_RS08400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWM47_RS08470	COG0673	inositol 2-dehydrogenase activity
CWM47_RS08475	COG0673	inositol 2-dehydrogenase activity
CWM47_RS08505	COG4654	Cytochrome c, class I
CWM47_RS08530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CWM47_RS08530	COG0131	Imidazoleglycerol-phosphate dehydratase
CWM47_RS08540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWM47_RS08550	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CWM47_RS08560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWM47_RS08565	COG2205	protein histidine kinase activity
CWM47_RS08585	COG0006	proline dipeptidase activity
CWM47_RS08620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CWM47_RS08630	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CWM47_RS08630	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWM47_RS08645	COG2226	methyltransferase
CWM47_RS08650	COG0531	amino acid
CWM47_RS08655	COG1131	(ABC) transporter
CWM47_RS08670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CWM47_RS08675	COG2271	Major facilitator Superfamily
CWM47_RS08690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWM47_RS08700	COG0612	Peptidase, M16
CWM47_RS08715	COG1252	NADH dehydrogenase
CWM47_RS08720	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS08735	COG1858	cytochrome C peroxidase
CWM47_RS08745	COG0671	phosphoesterase, PA-phosphatase related
CWM47_RS08760	COG1595	DNA-templated transcription, initiation
CWM47_RS08785	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CWM47_RS08795	COG0351	phosphomethylpyrimidine kinase
CWM47_RS08800	COG0351	phosphomethylpyrimidine kinase
CWM47_RS08800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CWM47_RS08800	COG0352	thiamine-phosphate diphosphorylase activity
CWM47_RS08810	COG0577	efflux transmembrane transporter activity
CWM47_RS08835	COG0346	lactoylglutathione lyase activity
CWM47_RS08840	COG2207	Transcriptional regulator
CWM47_RS08855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWM47_RS08895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CWM47_RS08915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CWM47_RS08920	COG1570	exodeoxyribonuclease VII activity
CWM47_RS08935	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS08945	COG0542	response to heat
CWM47_RS08960	COG0501	Belongs to the peptidase M48B family
CWM47_RS08975	COG2814	Major facilitator Superfamily
CWM47_RS09005	COG0166	Belongs to the GPI family
CWM47_RS09020	COG1648	precorrin-2 dehydrogenase activity
CWM47_RS09020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CWM47_RS09070	COG3279	Response regulator of the LytR AlgR family
CWM47_RS09105	COG1388	LysM domain
CWM47_RS09105	COG0791	NLP P60 protein
CWM47_RS09105	COG3103	Sh3 type 3 domain protein
CWM47_RS09115	COG1490	D-aminoacyl-tRNA deacylase activity
CWM47_RS09150	COG5002	protein histidine kinase activity
CWM47_RS09155	COG0745	RESPONSE REGULATOR receiver
CWM47_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS09250	COG2124	cytochrome p450
CWM47_RS09260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CWM47_RS09270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CWM47_RS09295	COG4771	TonB-dependent receptor
CWM47_RS09315	COG0673	inositol 2-dehydrogenase activity
CWM47_RS09375	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CWM47_RS09380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CWM47_RS09395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CWM47_RS09400	COG5002	protein histidine kinase activity
CWM47_RS09400	COG3850	Histidine kinase
CWM47_RS09410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWM47_RS09420	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CWM47_RS09430	COG2721	sulfolactate sulfo-lyase activity
CWM47_RS09435	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS09440	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWM47_RS09450	COG1070	Carbohydrate kinase
CWM47_RS09460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CWM47_RS09470	COG0137	argininosuccinate synthase activity
CWM47_RS09485	COG0640	Transcriptional regulator
CWM47_RS09505	COG1597	lipid kinase activity
CWM47_RS09510	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS09520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWM47_RS09520	COG2755	lipolytic protein G-D-S-L family
CWM47_RS09535	COG0156	8-amino-7-oxononanoate synthase activity
CWM47_RS09540	COG0439	Biotin carboxylase
CWM47_RS09565	COG4932	domain protein
CWM47_RS09580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CWM47_RS09585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWM47_RS09590	COG3275	phosphorelay sensor kinase activity
CWM47_RS09595	COG3279	Response regulator of the LytR AlgR family
CWM47_RS09600	COG4251	negative regulation of phosphorylation
CWM47_RS09605	COG0023	Translation Initiation Factor
CWM47_RS09610	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CWM47_RS09615	COG3104	oligopeptide transport
CWM47_RS09630	COG2267	carboxylic ester hydrolase activity
CWM47_RS09650	COG0719	Fe-S assembly protein
CWM47_RS09665	COG2814	Major facilitator Superfamily
CWM47_RS09670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWM47_RS09700	COG3279	Response regulator of the LytR AlgR family
CWM47_RS09710	COG3279	Response regulator of the LytR AlgR family
CWM47_RS09715	COG3275	phosphorelay sensor kinase activity
CWM47_RS09745	COG4206	TonB-dependent receptor
CWM47_RS09745	COG1629	transport
CWM47_RS09760	COG4977	sequence-specific DNA binding
CWM47_RS09760	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS09765	COG4221	oxidoreductase activity
CWM47_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS09775	COG4977	sequence-specific DNA binding
CWM47_RS09775	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS09795	COG2205	protein histidine kinase activity
CWM47_RS09795	COG3292	Two component regulator propeller
CWM47_RS09795	COG0745	RESPONSE REGULATOR receiver
CWM47_RS09820	COG1858	cytochrome C peroxidase
CWM47_RS09825	COG2957	Belongs to the agmatine deiminase family
CWM47_RS09865	COG4804	nuclease activity
CWM47_RS09895	COG1203	CRISPR-associated helicase, Cas3
CWM47_RS09905	COG1518	maintenance of DNA repeat elements
CWM47_RS09910	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CWM47_RS09915	COG1278	Cold shock
CWM47_RS09955	COG4251	negative regulation of phosphorylation
CWM47_RS10035	COG4221	oxidoreductase activity
CWM47_RS10090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWM47_RS10110	COG2801	Transposase and inactivated derivatives
CWM47_RS10160	COG0456	acetyltransferase
CWM47_RS10175	COG2003	Belongs to the UPF0758 family
CWM47_RS10200	COG1061	Type III restriction enzyme res subunit
CWM47_RS10205	COG0582	viral genome integration into host DNA
CWM47_RS10330	COG0247	lactate metabolic process
CWM47_RS10330	COG2181	nitrate reductase activity
CWM47_RS10335	COG2181	nitrate reductase activity
CWM47_RS10335	COG0247	lactate metabolic process
CWM47_RS10355	COG0194	GDP metabolic process
CWM47_RS10360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CWM47_RS10370	COG2234	aminopeptidase activity
CWM47_RS10375	COG0215	cysteine-tRNA ligase activity
CWM47_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS10405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CWM47_RS10415	COG0604	alcohol dehydrogenase
CWM47_RS10420	COG0156	8-amino-7-oxononanoate synthase activity
CWM47_RS10425	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CWM47_RS10430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWM47_RS10435	COG0527	aspartate kinase activity
CWM47_RS10440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CWM47_RS10455	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CWM47_RS10460	COG0051	transcription antitermination factor activity, RNA binding
CWM47_RS10465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CWM47_RS10470	COG1132	(ABC) transporter
CWM47_RS10485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWM47_RS10495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CWM47_RS10515	COG3047	cAMP biosynthetic process
CWM47_RS10515	COG2885	chlorophyll binding
CWM47_RS10550	COG0149	triose-phosphate isomerase activity
CWM47_RS10555	COG0750	zinc metalloprotease
CWM47_RS10560	COG5002	protein histidine kinase activity
CWM47_RS10565	COG0745	RESPONSE REGULATOR receiver
CWM47_RS10570	COG0628	permease
CWM47_RS10590	COG2264	protein methyltransferase activity
CWM47_RS10610	COG1874	Beta-galactosidase
CWM47_RS10620	COG3250	beta-galactosidase activity
CWM47_RS10640	COG4771	TonB-dependent receptor
CWM47_RS10645	COG1609	Transcriptional regulator
CWM47_RS10665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWM47_RS10675	COG0579	oxidoreductase
CWM47_RS10685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CWM47_RS10690	COG1895	HEPN domain
CWM47_RS10700	COG0527	aspartate kinase activity
CWM47_RS10705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CWM47_RS10720	COG1629	transport
CWM47_RS10725	COG0626	cystathionine gamma-synthase activity
CWM47_RS10745	COG1960	acyl-CoA dehydrogenase activity
CWM47_RS10760	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CWM47_RS10775	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CWM47_RS10780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWM47_RS10785	COG0688	phosphatidylethanolamine metabolic process
CWM47_RS10855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWM47_RS10865	COG0138	bifunctional purine biosynthesis protein purh
CWM47_RS10890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CWM47_RS10915	COG1959	2 iron, 2 sulfur cluster binding
CWM47_RS10935	COG0242	peptide deformylase activity
CWM47_RS10940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CWM47_RS10975	COG0673	inositol 2-dehydrogenase activity
CWM47_RS10980	COG0363	glucosamine-6-phosphate deaminase activity
CWM47_RS11025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CWM47_RS11040	COG2223	nitrite transmembrane transporter activity
CWM47_RS11060	COG0612	Peptidase, M16
CWM47_RS11070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWM47_RS11070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWM47_RS11080	COG0531	amino acid
CWM47_RS11085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWM47_RS11110	COG0022	dehydrogenase e1 component
CWM47_RS11110	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWM47_RS11130	COG1435	thymidine kinase activity
CWM47_RS11150	COG1127	ABC transporter
CWM47_RS11155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWM47_RS11160	COG0300	oxidoreductase activity
CWM47_RS11170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CWM47_RS11180	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CWM47_RS11185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWM47_RS11195	COG0571	ribonuclease III activity
CWM47_RS11200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWM47_RS11205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWM47_RS11210	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CWM47_RS11240	COG1595	DNA-templated transcription, initiation
CWM47_RS11265	COG2972	Histidine kinase
CWM47_RS11275	COG3279	Response regulator of the LytR AlgR family
CWM47_RS11280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CWM47_RS11285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CWM47_RS11290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWM47_RS11300	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CWM47_RS11310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CWM47_RS11330	COG1136	(ABC) transporter
CWM47_RS11340	COG0673	inositol 2-dehydrogenase activity
CWM47_RS11350	COG1960	acyl-CoA dehydrogenase activity
CWM47_RS11355	COG0183	Belongs to the thiolase family
CWM47_RS11360	COG0839	Belongs to the complex I subunit 6 family
CWM47_RS11365	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWM47_RS11370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CWM47_RS11375	COG1034	ATP synthesis coupled electron transport
CWM47_RS11385	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CWM47_RS11390	COG0649	NAD binding
CWM47_RS11395	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWM47_RS11400	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWM47_RS11405	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWM47_RS11420	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CWM47_RS11425	COG0563	adenylate kinase activity
CWM47_RS11460	COG0811	peptide transport
CWM47_RS11490	COG2226	methyltransferase
CWM47_RS11500	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CWM47_RS11510	COG2373	Large extracellular alpha-helical protein
CWM47_RS11520	COG4953	penicillin-binding protein 1C
CWM47_RS11525	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CWM47_RS11540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CWM47_RS11555	COG1477	protein flavinylation
CWM47_RS11560	COG0673	inositol 2-dehydrogenase activity
CWM47_RS11575	COG0277	FAD linked oxidase domain protein
CWM47_RS11575	COG0247	lactate metabolic process
CWM47_RS11580	COG1629	transport
CWM47_RS11580	COG4206	TonB-dependent receptor
CWM47_RS11585	COG0702	epimerase
CWM47_RS11595	COG4771	TonB-dependent receptor
CWM47_RS11600	COG0702	epimerase
CWM47_RS11625	COG1595	DNA-templated transcription, initiation
CWM47_RS11630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWM47_RS11655	COG2137	regulation of response to DNA damage stimulus
CWM47_RS11740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CWM47_RS11755	COG1228	amidohydrolase
CWM47_RS11770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CWM47_RS11780	COG0148	phosphopyruvate hydratase activity
CWM47_RS11790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWM47_RS11795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CWM47_RS11800	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWM47_RS11810	COG0659	secondary active sulfate transmembrane transporter activity
CWM47_RS11815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWM47_RS11820	COG3852	Histidine kinase
CWM47_RS11865	COG2204	response regulator
CWM47_RS11870	COG3940	Belongs to the glycosyl hydrolase 43 family
CWM47_RS11880	COG4654	Cytochrome c, class I
CWM47_RS11900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWM47_RS11930	COG0588	phosphoglycerate mutase activity
CWM47_RS11960	COG2814	Major facilitator Superfamily
CWM47_RS12000	COG0367	asparagine synthase
CWM47_RS12015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWM47_RS12035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWM47_RS12045	COG2808	Putative FMN-binding domain
CWM47_RS12075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CWM47_RS12095	COG0268	Binds directly to 16S ribosomal RNA
CWM47_RS12100	COG2003	Belongs to the UPF0758 family
CWM47_RS12105	COG1187	pseudouridine synthase activity
CWM47_RS12110	COG0708	Exodeoxyribonuclease III
CWM47_RS12115	COG2211	Major facilitator Superfamily
CWM47_RS12130	COG4712	double-strand break repair protein
CWM47_RS12140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CWM47_RS12170	COG0673	inositol 2-dehydrogenase activity
CWM47_RS12180	COG0745	RESPONSE REGULATOR receiver
CWM47_RS12180	COG3292	Two component regulator propeller
CWM47_RS12180	COG2205	protein histidine kinase activity
CWM47_RS12210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWM47_RS12215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CWM47_RS12220	COG1960	acyl-CoA dehydrogenase activity
CWM47_RS12230	COG1496	oxidoreductase activity
CWM47_RS12245	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CWM47_RS12265	COG0673	inositol 2-dehydrogenase activity
CWM47_RS12275	COG2885	chlorophyll binding
CWM47_RS12275	COG3047	cAMP biosynthetic process
CWM47_RS12300	COG0443	Heat shock 70 kDa protein
CWM47_RS12310	COG4251	negative regulation of phosphorylation
CWM47_RS12320	COG2197	response regulator
CWM47_RS12325	COG4251	negative regulation of phosphorylation
CWM47_RS12330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWM47_RS12370	COG0165	Argininosuccinate lyase
CWM47_RS12395	COG0135	phosphoribosylanthranilate isomerase activity
CWM47_RS12405	COG0071	Belongs to the small heat shock protein (HSP20) family
CWM47_RS12420	COG0318	PFAM AMP-dependent synthetase and ligase
CWM47_RS12425	COG0813	purine-nucleoside phosphorylase activity
CWM47_RS12435	COG2353	YceI-like domain
CWM47_RS12455	COG0424	maF-like protein
CWM47_RS12475	COG4654	Cytochrome c, class I
CWM47_RS12485	COG0540	Belongs to the ATCase OTCase family
CWM47_RS12515	COG0393	Putative heavy-metal-binding
CWM47_RS12535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CWM47_RS12540	COG1561	YicC-like family, N-terminal region
CWM47_RS12545	COG2094	Belongs to the DNA glycosylase MPG family
CWM47_RS12595	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CWM47_RS12615	COG1215	transferase activity, transferring glycosyl groups
CWM47_RS12630	COG1216	Glycosyl transferase, family 2
CWM47_RS12640	COG0656	L-ascorbic acid biosynthetic process
CWM47_RS12655	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS12690	COG2205	protein histidine kinase activity
CWM47_RS12690	COG0784	Response regulator, receiver
CWM47_RS12695	COG2204	response regulator
CWM47_RS12745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWM47_RS12765	COG3507	Belongs to the glycosyl hydrolase 43 family
CWM47_RS12770	COG0745	RESPONSE REGULATOR receiver
CWM47_RS12770	COG2205	protein histidine kinase activity
CWM47_RS12770	COG3292	Two component regulator propeller
CWM47_RS12775	COG3250	beta-galactosidase activity
CWM47_RS12795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWM47_RS12840	COG0702	epimerase
CWM47_RS12845	COG4771	TonB-dependent receptor
CWM47_RS12865	COG5002	protein histidine kinase activity
CWM47_RS12870	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CWM47_RS12870	COG3266	domain, Protein
CWM47_RS12870	COG4932	domain protein
CWM47_RS12900	COG2851	Citrate transporter
CWM47_RS12905	COG2272	Belongs to the type-B carboxylesterase lipase family
CWM47_RS12920	COG1125	glycine betaine transport
CWM47_RS12920	COG0517	IMP dehydrogenase activity
CWM47_RS12950	COG3254	rhamnose metabolic process
CWM47_RS12955	COG0738	Major facilitator superfamily
CWM47_RS12960	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS12965	COG1482	cell wall glycoprotein biosynthetic process
CWM47_RS12990	COG1652	LysM domain
CWM47_RS13010	COG1733	regulation of RNA biosynthetic process
CWM47_RS13015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CWM47_RS13035	COG0307	riboflavin synthase, alpha
CWM47_RS13090	COG0463	Glycosyl transferase, family 2
CWM47_RS13125	COG1418	mRNA catabolic process
CWM47_RS13150	COG4771	TonB-dependent receptor
CWM47_RS13155	COG0702	epimerase
CWM47_RS13180	COG1193	negative regulation of DNA recombination
CWM47_RS13185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWM47_RS13210	COG1629	transport
CWM47_RS13235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWM47_RS13280	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CWM47_RS13290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CWM47_RS13300	COG1475	DNA binding
CWM47_RS13305	COG1192	Involved in chromosome partitioning
CWM47_RS13330	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CWM47_RS13335	COG0667	Aldo Keto reductase
CWM47_RS13345	COG2308	Evidence 4 Homologs of previously reported genes of
CWM47_RS13375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWM47_RS13380	COG0483	inositol monophosphate 1-phosphatase activity
CWM47_RS13385	COG2318	DinB family
CWM47_RS13410	COG0598	Magnesium transport protein CorA
CWM47_RS13415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWM47_RS13440	COG0659	secondary active sulfate transmembrane transporter activity
CWM47_RS13465	COG0028	Belongs to the TPP enzyme family
CWM47_RS13485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWM47_RS13520	COG0363	glucosamine-6-phosphate deaminase activity
CWM47_RS13535	COG0673	inositol 2-dehydrogenase activity
CWM47_RS13545	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS13580	COG2353	YceI-like domain
CWM47_RS13585	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CWM47_RS13610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWM47_RS13630	COG1349	DNA-binding transcription factor activity
CWM47_RS13640	COG3959	Transketolase, thiamine diphosphate binding domain
CWM47_RS13650	COG3958	Transketolase
CWM47_RS13665	COG1129	ABC transporter
CWM47_RS13670	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWM47_RS13675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CWM47_RS13725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWM47_RS13730	COG0427	acetyl-CoA hydrolase
CWM47_RS13735	COG2723	6-phospho-beta-galactosidase activity
CWM47_RS13765	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CWM47_RS13765	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CWM47_RS13765	COG1703	isobutyryl-CoA mutase activity
CWM47_RS13770	COG3279	Response regulator of the LytR AlgR family
CWM47_RS13770	COG5000	phosphorelay sensor kinase activity
CWM47_RS13825	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS13840	COG4771	TonB-dependent receptor
CWM47_RS13870	COG0823	Involved in the tonB-independent uptake of proteins
CWM47_RS13875	COG0436	Aminotransferase
CWM47_RS13880	COG1611	Belongs to the LOG family
CWM47_RS13890	COG1702	phosphate starvation-inducible protein PhoH
CWM47_RS13905	COG2333	competence protein COMEC
CWM47_RS13905	COG0658	competence protein
CWM47_RS13920	COG0175	sulfate reduction
CWM47_RS13925	COG0175	sulfate reduction
CWM47_RS13940	COG0730	response to heat
CWM47_RS13945	COG5505	Protein of unknown function (DUF819)
CWM47_RS13950	COG1404	Belongs to the peptidase S8 family
CWM47_RS13960	COG0495	leucyl-tRNA aminoacylation
CWM47_RS13965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWM47_RS13985	COG2205	protein histidine kinase activity
CWM47_RS13990	COG3153	acetyltransferase
CWM47_RS13990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWM47_RS14005	COG0052	Belongs to the universal ribosomal protein uS2 family
CWM47_RS14015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWM47_RS14025	COG0745	RESPONSE REGULATOR receiver
CWM47_RS14025	COG0745	RESPONSE REGULATOR receiver
CWM47_RS14025	COG3292	Two component regulator propeller
CWM47_RS14025	COG2205	protein histidine kinase activity
CWM47_RS14025	COG2205	protein histidine kinase activity
CWM47_RS14025	COG3292	Two component regulator propeller
CWM47_RS14035	COG1301	dicarboxylic acid transport
CWM47_RS14045	COG4152	abc transporter atp-binding protein
CWM47_RS14070	COG0101	tRNA pseudouridine synthase activity
CWM47_RS14100	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CWM47_RS14125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CWM47_RS14150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWM47_RS14185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWM47_RS14200	COG0583	DNA-binding transcription factor activity
CWM47_RS14210	COG1024	Enoyl-CoA hydratase
CWM47_RS14220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CWM47_RS14235	COG2814	Major facilitator Superfamily
CWM47_RS14245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWM47_RS14255	COG0494	nUDIX hydrolase
CWM47_RS14270	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CWM47_RS14285	COG1054	Belongs to the UPF0176 family
CWM47_RS14290	COG1428	Deoxynucleoside kinase
CWM47_RS14340	COG2133	pyrroloquinoline quinone binding
CWM47_RS14345	COG0673	inositol 2-dehydrogenase activity
CWM47_RS14405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CWM47_RS14410	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CWM47_RS14420	COG1012	belongs to the aldehyde dehydrogenase family
CWM47_RS14425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWM47_RS14430	COG1953	Uracil, thiamine, allantoin
CWM47_RS14495	COG1663	tetraacyldisaccharide 4'-kinase activity
CWM47_RS14515	COG0504	CTP synthase activity
CWM47_RS14520	COG0706	membrane insertase activity
CWM47_RS14530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CWM47_RS14540	COG1216	Glycosyl transferase, family 2
CWM47_RS14550	COG0124	histidyl-tRNA synthetase
CWM47_RS14595	COG2171	N-acyltransferase activity
CWM47_RS14605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CWM47_RS14620	COG4251	negative regulation of phosphorylation
CWM47_RS14630	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CWM47_RS14660	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CWM47_RS14665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CWM47_RS14665	COG1648	precorrin-2 dehydrogenase activity
CWM47_RS14710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWM47_RS14715	COG1185	polyribonucleotide nucleotidyltransferase activity
CWM47_RS14720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CWM47_RS14750	COG1472	Belongs to the glycosyl hydrolase 3 family
CWM47_RS14790	COG0463	Glycosyl transferase, family 2
CWM47_RS14825	COG3682	Transcriptional regulator
CWM47_RS14855	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CWM47_RS14875	COG0662	Cupin 2, conserved barrel domain protein
CWM47_RS14875	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CWM47_RS14895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWM47_RS14900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CWM47_RS14910	COG2885	chlorophyll binding
CWM47_RS14915	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CWM47_RS14915	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CWM47_RS14940	COG1216	Glycosyl transferase, family 2
CWM47_RS14965	COG2234	aminopeptidase activity
CWM47_RS14990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CWM47_RS15045	COG1063	alcohol dehydrogenase
CWM47_RS15055	COG3485	protocatechuate 3,4-dioxygenase
CWM47_RS15060	COG3485	protocatechuate 3,4-dioxygenase
CWM47_RS15065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CWM47_RS15070	COG0183	Belongs to the thiolase family
CWM47_RS15075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWM47_RS15090	COG1131	(ABC) transporter
CWM47_RS15095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CWM47_RS15105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CWM47_RS15110	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CWM47_RS15120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CWM47_RS15140	COG0552	protein localization to endoplasmic reticulum
CWM47_RS15150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWM47_RS15155	COG0649	NAD binding
CWM47_RS15160	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CWM47_RS15170	COG1522	sequence-specific DNA binding
CWM47_RS15185	COG1649	PFAM Uncharacterised BCR, COG1649
CWM47_RS15190	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CWM47_RS15210	COG0584	glycerophosphoryl diester phosphodiesterase
CWM47_RS15225	COG4771	TonB-dependent receptor
CWM47_RS15235	COG1595	DNA-templated transcription, initiation
CWM47_RS15255	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CWM47_RS15265	COG2183	response to ionizing radiation
CWM47_RS15265	COG0539	negative regulation of cytoplasmic translation
CWM47_RS15280	COG0437	4 iron, 4 sulfur cluster binding
CWM47_RS15305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CWM47_RS15310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWM47_RS15315	COG1612	heme a metabolic process
CWM47_RS15320	COG0109	protoheme IX farnesyltransferase activity
CWM47_RS15325	COG1845	cytochrome c oxidase, subunit III
CWM47_RS15330	COG1845	cytochrome c oxidase, subunit III
CWM47_RS15340	COG1999	signal sequence binding
CWM47_RS15345	COG2322	membrane
CWM47_RS15395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWM47_RS15415	COG0513	Belongs to the DEAD box helicase family
CWM47_RS15420	COG3001	Fructosamine kinase
CWM47_RS15425	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CWM47_RS15430	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWM47_RS15440	COG1446	asparaginase
CWM47_RS15445	COG0788	formyltetrahydrofolate deformylase activity
CWM47_RS15450	COG3142	Participates in the control of copper homeostasis
CWM47_RS15470	COG1297	OPT oligopeptide transporter protein
CWM47_RS15505	COG4946	Tricorn protease homolog
CWM47_RS15505	COG0793	Belongs to the peptidase S41A family
CWM47_RS15525	COG2706	6-phosphogluconolactonase activity
CWM47_RS15535	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CWM47_RS15545	COG0077	Prephenate dehydratase
CWM47_RS15545	COG1605	Chorismate mutase
CWM47_RS15560	COG1252	NADH dehydrogenase
CWM47_RS15570	COG3591	Belongs to the peptidase S1B family
CWM47_RS15580	COG1506	peptidase
CWM47_RS15580	COG4946	Tricorn protease homolog
CWM47_RS15580	COG0823	Involved in the tonB-independent uptake of proteins
CWM47_RS15615	COG3279	Response regulator of the LytR AlgR family
CWM47_RS15630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CWM47_RS15635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWM47_RS15640	COG0463	Glycosyl transferase, family 2
CWM47_RS15650	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CWM47_RS15650	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CWM47_RS15665	COG0505	Belongs to the CarA family
CWM47_RS15670	COG0203	ribosomal protein L17
CWM47_RS15675	COG0202	RNA polymerase activity
CWM47_RS15680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CWM47_RS15685	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CWM47_RS15690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CWM47_RS15695	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWM47_RS15700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWM47_RS15705	COG0024	Methionine aminopeptidase
CWM47_RS15715	COG0200	Binds to the 23S rRNA
CWM47_RS15720	COG1841	ribosomal large subunit assembly
CWM47_RS15725	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CWM47_RS15730	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CWM47_RS15735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CWM47_RS15740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CWM47_RS15745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CWM47_RS15750	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CWM47_RS15755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CWM47_RS15760	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CWM47_RS15765	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CWM47_RS15770	COG0255	Belongs to the universal ribosomal protein uL29 family
CWM47_RS15775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CWM47_RS15780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CWM47_RS15785	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CWM47_RS15790	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CWM47_RS15795	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CWM47_RS15800	COG0089	rRNA binding
CWM47_RS15805	COG0088	Forms part of the polypeptide exit tunnel
CWM47_RS15810	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CWM47_RS15830	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS15835	COG0612	Peptidase, M16
CWM47_RS15840	COG0612	Peptidase, M16
CWM47_RS15905	COG0673	inositol 2-dehydrogenase activity
CWM47_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS15920	COG4821	SIS domain
CWM47_RS15930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CWM47_RS15935	COG1607	acyl-coa hydrolase
CWM47_RS15940	COG0316	Belongs to the HesB IscA family
CWM47_RS15945	COG0346	lactoylglutathione lyase activity
CWM47_RS15955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWM47_RS15970	COG1162	GTPase activity
CWM47_RS15975	COG1519	Transferase
CWM47_RS15990	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CWM47_RS16015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWM47_RS16050	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS16055	COG1704	LemA family
CWM47_RS16065	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CWM47_RS16075	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CWM47_RS16085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CWM47_RS16100	COG1674	ftsk spoiiie
CWM47_RS16105	COG0167	dihydroorotate dehydrogenase activity
CWM47_RS16120	COG0318	PFAM AMP-dependent synthetase and ligase
CWM47_RS16140	COG1629	transport
CWM47_RS16140	COG4206	TonB-dependent receptor
CWM47_RS16180	COG1595	DNA-templated transcription, initiation
CWM47_RS16210	COG0557	exoribonuclease II activity
CWM47_RS16225	COG0321	lipoyl(octanoyl) transferase activity
CWM47_RS16230	COG0792	nuclease activity
CWM47_RS16245	COG2318	DinB family
CWM47_RS16270	COG2205	protein histidine kinase activity
CWM47_RS16270	COG0784	Response regulator, receiver
CWM47_RS16285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWM47_RS16290	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CWM47_RS16305	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CWM47_RS16315	COG0419	ATPase involved in DNA repair
CWM47_RS16320	COG0420	3'-5' exonuclease activity
CWM47_RS16340	COG4974	Belongs to the 'phage' integrase family
CWM47_RS16365	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CWM47_RS16465	COG1515	deoxyribonuclease V activity
CWM47_RS16470	COG2824	Alkylphosphonate utilization operon protein PhnA
CWM47_RS16475	COG1294	oxidase, subunit
CWM47_RS16480	COG1271	oxidase subunit
CWM47_RS16500	COG0415	Belongs to the DNA photolyase family
CWM47_RS16510	COG1629	transport
CWM47_RS16525	COG3250	beta-galactosidase activity
CWM47_RS16540	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS16545	COG2271	Major facilitator Superfamily
CWM47_RS16555	COG1312	Catalyzes the dehydration of D-mannonate
CWM47_RS16560	COG3661	Belongs to the glycosyl hydrolase 67 family
CWM47_RS16565	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS16600	COG0673	inositol 2-dehydrogenase activity
CWM47_RS16605	COG2203	Gaf domain
CWM47_RS16605	COG4585	Histidine kinase
CWM47_RS16635	COG4251	negative regulation of phosphorylation
CWM47_RS16650	COG0318	PFAM AMP-dependent synthetase and ligase
CWM47_RS16670	COG0784	Response regulator, receiver
CWM47_RS16670	COG2198	Histidine kinase
CWM47_RS16670	COG5002	protein histidine kinase activity
CWM47_RS16675	COG3279	Response regulator of the LytR AlgR family
CWM47_RS16680	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CWM47_RS16700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWM47_RS16705	COG0534	Mate efflux family protein
CWM47_RS16720	COG0656	L-ascorbic acid biosynthetic process
CWM47_RS16735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CWM47_RS16750	COG0739	heme binding
CWM47_RS16755	COG3548	integral membrane protein
CWM47_RS16760	COG0531	amino acid
CWM47_RS16765	COG0083	homoserine kinase activity
CWM47_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS16785	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CWM47_RS16840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CWM47_RS16845	COG3119	arylsulfatase activity
CWM47_RS16850	COG0659	secondary active sulfate transmembrane transporter activity
CWM47_RS16865	COG0277	FAD linked oxidase domain protein
CWM47_RS16865	COG0247	lactate metabolic process
CWM47_RS16875	COG0668	transmembrane transport
CWM47_RS16890	COG1136	(ABC) transporter
CWM47_RS16890	COG0577	efflux transmembrane transporter activity
CWM47_RS16895	COG1136	(ABC) transporter
CWM47_RS16895	COG0577	efflux transmembrane transporter activity
CWM47_RS16930	COG1595	DNA-templated transcription, initiation
CWM47_RS16945	COG4771	TonB-dependent receptor
CWM47_RS16970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWM47_RS16970	COG2207	Transcriptional regulator
CWM47_RS16985	COG0577	efflux transmembrane transporter activity
CWM47_RS16990	COG2226	methyltransferase
CWM47_RS16995	COG1136	(ABC) transporter
CWM47_RS16995	COG0577	efflux transmembrane transporter activity
CWM47_RS17000	COG1136	(ABC) transporter
CWM47_RS17000	COG0577	efflux transmembrane transporter activity
CWM47_RS17030	COG0577	efflux transmembrane transporter activity
CWM47_RS17050	COG1136	(ABC) transporter
CWM47_RS17050	COG0577	efflux transmembrane transporter activity
CWM47_RS17075	COG0577	efflux transmembrane transporter activity
CWM47_RS17075	COG1136	(ABC) transporter
CWM47_RS17095	COG4251	negative regulation of phosphorylation
CWM47_RS17100	COG4251	negative regulation of phosphorylation
CWM47_RS17105	COG0577	efflux transmembrane transporter activity
CWM47_RS17105	COG1136	(ABC) transporter
CWM47_RS17125	COG0577	efflux transmembrane transporter activity
CWM47_RS17135	COG0577	efflux transmembrane transporter activity
CWM47_RS17140	COG0577	efflux transmembrane transporter activity
CWM47_RS17140	COG1136	(ABC) transporter
CWM47_RS17150	COG0577	efflux transmembrane transporter activity
CWM47_RS17155	COG0577	efflux transmembrane transporter activity
CWM47_RS17155	COG1136	(ABC) transporter
CWM47_RS17200	COG4191	Histidine kinase
CWM47_RS17225	COG4942	peptidase
CWM47_RS17235	COG0497	DNA recombination
CWM47_RS17270	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CWM47_RS17345	COG1484	DNA-dependent DNA replication
CWM47_RS17370	COG4251	negative regulation of phosphorylation
CWM47_RS17400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWM47_RS17425	COG0745	RESPONSE REGULATOR receiver
CWM47_RS17480	COG4584	PFAM Integrase catalytic
CWM47_RS17480	COG2390	Transcriptional regulator
CWM47_RS17485	COG1484	DNA-dependent DNA replication
CWM47_RS17520	COG0784	Response regulator, receiver
CWM47_RS17520	COG2205	protein histidine kinase activity
CWM47_RS17560	COG0640	Transcriptional regulator
CWM47_RS17615	COG5002	protein histidine kinase activity
CWM47_RS17620	COG0745	RESPONSE REGULATOR receiver
CWM47_RS17650	COG2226	methyltransferase
CWM47_RS17675	COG0667	Aldo Keto reductase
CWM47_RS17690	COG0656	L-ascorbic acid biosynthetic process
CWM47_RS17715	COG2801	Transposase and inactivated derivatives
CWM47_RS17750	COG1595	DNA-templated transcription, initiation
CWM47_RS17820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CWM47_RS17825	COG3217	Mosc domain protein beta barrel domain protein
CWM47_RS17825	COG0633	Ferredoxin
CWM47_RS17835	COG0346	lactoylglutathione lyase activity
CWM47_RS17860	COG1595	DNA-templated transcription, initiation
CWM47_RS17865	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CWM47_RS17870	COG1012	belongs to the aldehyde dehydrogenase family
CWM47_RS17985	COG1388	LysM domain
CWM47_RS17985	COG3942	CHAP domain
CWM47_RS17990	COG2204	response regulator
CWM47_RS17995	COG1846	Transcriptional regulator
CWM47_RS17995	COG1940	carbohydrate kinase activity
CWM47_RS18000	COG1629	transport
CWM47_RS18025	COG2884	Cell division ATP-binding protein ftsE
CWM47_RS18030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CWM47_RS18035	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWM47_RS18065	COG5000	phosphorelay sensor kinase activity
CWM47_RS18080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWM47_RS18090	COG1183	phosphatidylcholine synthase activity
CWM47_RS18095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWM47_RS18105	COG2267	carboxylic ester hydrolase activity
CWM47_RS18150	COG0799	negative regulation of ribosome biogenesis
CWM47_RS18155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWM47_RS18165	COG0318	PFAM AMP-dependent synthetase and ligase
CWM47_RS18170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CWM47_RS18180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CWM47_RS18185	COG0187	DNA topoisomerase II activity
CWM47_RS18195	COG0686	Belongs to the AlaDH PNT family
CWM47_RS18200	COG0802	atpase or kinase
CWM47_RS18205	COG0673	inositol 2-dehydrogenase activity
CWM47_RS18215	COG1629	transport
CWM47_RS18220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWM47_RS18235	COG3655	Transcriptional regulator
CWM47_RS18315	COG0596	Alpha beta hydrolase
CWM47_RS18320	COG0346	lactoylglutathione lyase activity
CWM47_RS18325	COG0783	Belongs to the Dps family
CWM47_RS18335	COG4977	sequence-specific DNA binding
CWM47_RS18335	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS18345	COG3604	Transcriptional regulator
CWM47_RS18365	COG1477	protein flavinylation
CWM47_RS18370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CWM47_RS18395	COG1609	Transcriptional regulator
CWM47_RS18395	COG2207	Transcriptional regulator
CWM47_RS18400	COG0667	Aldo Keto reductase
CWM47_RS18405	COG4447	cellulose binding
CWM47_RS18410	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CWM47_RS18415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWM47_RS18420	COG4558	Periplasmic binding protein
CWM47_RS18460	COG2201	protein-glutamate methylesterase activity
CWM47_RS18470	COG2115	Belongs to the xylose isomerase family
CWM47_RS18500	COG3507	Belongs to the glycosyl hydrolase 43 family
CWM47_RS18505	COG2382	esterase
CWM47_RS18510	COG2755	lipolytic protein G-D-S-L family
CWM47_RS18510	COG0657	acetylesterase activity
CWM47_RS18520	COG2382	esterase
CWM47_RS18525	COG3507	Belongs to the glycosyl hydrolase 43 family
CWM47_RS18525	COG2382	esterase
CWM47_RS18525	COG3693	PFAM glycoside hydrolase, family 10
CWM47_RS18530	COG3693	PFAM glycoside hydrolase, family 10
CWM47_RS18530	COG2382	esterase
CWM47_RS18535	COG3693	PFAM glycoside hydrolase, family 10
CWM47_RS18535	COG2382	esterase
CWM47_RS18535	COG3507	Belongs to the glycosyl hydrolase 43 family
CWM47_RS18570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWM47_RS18605	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CWM47_RS18610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CWM47_RS18640	COG0745	RESPONSE REGULATOR receiver
CWM47_RS18640	COG3292	Two component regulator propeller
CWM47_RS18640	COG2205	protein histidine kinase activity
CWM47_RS18685	COG2217	Heavy metal translocating P-type atpase
CWM47_RS18740	COG3292	Two component regulator propeller
CWM47_RS18740	COG2205	protein histidine kinase activity
CWM47_RS18740	COG0745	RESPONSE REGULATOR receiver
CWM47_RS18765	COG5002	protein histidine kinase activity
CWM47_RS18765	COG3850	Histidine kinase
CWM47_RS18770	COG0745	RESPONSE REGULATOR receiver
CWM47_RS18775	COG3002	Belongs to the UPF0753 family
CWM47_RS18790	COG1473	amidohydrolase
CWM47_RS18815	COG0513	Belongs to the DEAD box helicase family
CWM47_RS18825	COG0513	Belongs to the DEAD box helicase family
CWM47_RS18830	COG0513	Belongs to the DEAD box helicase family
CWM47_RS18860	COG0300	oxidoreductase activity
CWM47_RS18910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWM47_RS18920	COG2814	Major facilitator Superfamily
CWM47_RS18945	COG0596	Alpha beta hydrolase
CWM47_RS18955	COG0154	amidase activity
CWM47_RS18960	COG3685	Protein conserved in bacteria
CWM47_RS18965	COG0405	Gamma-glutamyltransferase
CWM47_RS19000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWM47_RS19020	COG1363	Peptidase, m42
CWM47_RS19030	COG1106	Psort location Cytoplasmic, score
CWM47_RS19045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CWM47_RS19070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWM47_RS19075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CWM47_RS19080	COG0791	NLP P60 protein
CWM47_RS19110	COG0778	Nitroreductase
CWM47_RS19130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWM47_RS19135	COG3938	Belongs to the proline racemase family
CWM47_RS19140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWM47_RS19155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWM47_RS19160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWM47_RS19160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWM47_RS19170	COG1132	(ABC) transporter
CWM47_RS19180	COG1253	flavin adenine dinucleotide binding
CWM47_RS19190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CWM47_RS19205	COG0517	IMP dehydrogenase activity
CWM47_RS19210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWM47_RS19220	COG0326	Molecular chaperone. Has ATPase activity
CWM47_RS19230	COG3781	membrane
CWM47_RS19235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CWM47_RS19240	COG0335	large ribosomal subunit rRNA binding
CWM47_RS19245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWM47_RS19245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CWM47_RS19295	COG1138	Cytochrome C-type biogenesis protein
CWM47_RS19305	COG1253	flavin adenine dinucleotide binding
CWM47_RS19310	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CWM47_RS19330	COG0488	(ABC) transporter
CWM47_RS19335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWM47_RS19340	COG3119	arylsulfatase activity
CWM47_RS19390	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CWM47_RS19405	COG0009	L-threonylcarbamoyladenylate synthase
CWM47_RS19430	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CWM47_RS19435	COG0564	pseudouridine synthase activity
CWM47_RS19445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWM47_RS19460	COG0336	Belongs to the RNA methyltransferase TrmD family
CWM47_RS19465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CWM47_RS19470	COG0228	four-way junction DNA binding
CWM47_RS19485	COG4771	TonB-dependent receptor
CWM47_RS19495	COG1193	negative regulation of DNA recombination
CWM47_RS19500	COG4302	ethanolamine ammonia-lyase activity
CWM47_RS19505	COG4303	Ethanolamine ammonia lyase large subunit
CWM47_RS19510	COG0531	amino acid
CWM47_RS19515	COG3511	phospholipase C
CWM47_RS19525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWM47_RS19570	COG1629	transport
CWM47_RS19580	COG0513	Belongs to the DEAD box helicase family
CWM47_RS19610	COG0667	Aldo Keto reductase
CWM47_RS19625	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CWM47_RS19635	COG3268	Saccharopine dehydrogenase
CWM47_RS19640	COG0673	inositol 2-dehydrogenase activity
CWM47_RS19650	COG4251	negative regulation of phosphorylation
CWM47_RS19675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CWM47_RS19680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWM47_RS19705	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CWM47_RS19725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWM47_RS19735	COG1295	ribonuclease BN
CWM47_RS19740	COG1216	Glycosyl transferase, family 2
CWM47_RS19745	COG0009	L-threonylcarbamoyladenylate synthase
CWM47_RS19760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWM47_RS19765	COG0544	peptidyl-prolyl cis-trans isomerase activity
CWM47_RS19775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWM47_RS19795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CWM47_RS19815	COG0384	phenazine biosynthesis protein PhzF
CWM47_RS19835	COG1073	alpha beta
CWM47_RS19840	COG1022	Amp-dependent synthetase and ligase
CWM47_RS19845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWM47_RS19850	COG0545	Peptidyl-prolyl cis-trans isomerase
CWM47_RS19865	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS19885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CWM47_RS19895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWM47_RS19900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWM47_RS19920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CWM47_RS19925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CWM47_RS19935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CWM47_RS19935	COG0758	DNA mediated transformation
CWM47_RS19950	COG4251	negative regulation of phosphorylation
CWM47_RS19955	COG4251	negative regulation of phosphorylation
CWM47_RS19960	COG4251	negative regulation of phosphorylation
CWM47_RS19965	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CWM47_RS19985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWM47_RS19995	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS20000	COG0110	maltose O-acetyltransferase activity
CWM47_RS20010	COG2091	lysine biosynthetic process via aminoadipic acid
CWM47_RS20020	COG2244	polysaccharide biosynthetic process
CWM47_RS20055	COG0233	cytoplasmic translational termination
CWM47_RS20060	COG0528	UMP kinase activity
CWM47_RS20080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWM47_RS20120	COG0575	Belongs to the CDS family
CWM47_RS20130	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CWM47_RS20150	COG0673	inositol 2-dehydrogenase activity
CWM47_RS20170	COG1940	carbohydrate kinase activity
CWM47_RS20175	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CWM47_RS20180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CWM47_RS20185	COG1605	Chorismate mutase
CWM47_RS20185	COG0077	Prephenate dehydratase
CWM47_RS20265	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS20280	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS20285	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS20300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWM47_RS20325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWM47_RS20330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CWM47_RS20335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CWM47_RS20345	COG1725	Transcriptional regulator
CWM47_RS20355	COG1131	(ABC) transporter
CWM47_RS20375	COG2363	Small membrane protein
CWM47_RS20380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CWM47_RS20390	COG0360	Binds together with S18 to 16S ribosomal RNA
CWM47_RS20395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CWM47_RS20400	COG0359	binds to the 23S rRNA
CWM47_RS20410	COG0489	protein tyrosine kinase activity
CWM47_RS20415	COG0316	Belongs to the HesB IscA family
CWM47_RS20415	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CWM47_RS20435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWM47_RS20560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CWM47_RS20690	COG2755	lipolytic protein G-D-S-L family
CWM47_RS20690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWM47_RS20830	COG2378	regulation of single-species biofilm formation
CWM47_RS20865	COG4974	Belongs to the 'phage' integrase family
CWM47_RS20925	COG4771	TonB-dependent receptor
CWM47_RS20965	COG1136	(ABC) transporter
CWM47_RS20965	COG0577	efflux transmembrane transporter activity
CWM47_RS21010	COG3279	Response regulator of the LytR AlgR family
CWM47_RS21020	COG2972	Histidine kinase
CWM47_RS21060	COG0577	efflux transmembrane transporter activity
CWM47_RS21075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWM47_RS21145	COG1742	UPF0060 membrane protein
CWM47_RS21285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWM47_RS21450	COG3279	Response regulator of the LytR AlgR family
CWM47_RS21455	COG0745	RESPONSE REGULATOR receiver
CWM47_RS21455	COG2972	Histidine kinase
CWM47_RS21465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWM47_RS21695	COG4227	nucleotidyltransferase activity
CWM47_RS21705	COG1192	Involved in chromosome partitioning
CWM47_RS21760	COG4251	negative regulation of phosphorylation
CWM47_RS21780	COG2205	protein histidine kinase activity
CWM47_RS21790	COG2080	2 iron, 2 sulfur cluster binding
CWM47_RS21795	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CWM47_RS21800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWM47_RS21810	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS21850	COG2353	YceI-like domain
CWM47_RS21855	COG0584	glycerophosphoryl diester phosphodiesterase
CWM47_RS21870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWM47_RS21875	COG2217	Heavy metal translocating P-type atpase
CWM47_RS21895	COG1629	transport
CWM47_RS21895	COG4206	TonB-dependent receptor
CWM47_RS21910	COG3278	Belongs to the heme-copper respiratory oxidase family
CWM47_RS21945	COG2205	protein histidine kinase activity
CWM47_RS22010	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CWM47_RS22050	COG0673	inositol 2-dehydrogenase activity
CWM47_RS22080	COG1595	DNA-templated transcription, initiation
CWM47_RS22095	COG2271	Major facilitator Superfamily
CWM47_RS22130	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CWM47_RS22140	COG4206	TonB-dependent receptor
CWM47_RS22140	COG1629	transport
CWM47_RS22170	COG1921	L-seryl-tRNASec selenium transferase activity
CWM47_RS22175	COG0251	oxidation-reduction process
CWM47_RS22190	COG1921	L-seryl-tRNASec selenium transferase activity
CWM47_RS22210	COG1629	transport
CWM47_RS22210	COG4206	TonB-dependent receptor
CWM47_RS22225	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWM47_RS22230	COG2271	Major facilitator Superfamily
CWM47_RS22235	COG0800	Aldolase
CWM47_RS22240	COG3734	2-keto-3-deoxy-galactonokinase
CWM47_RS22260	COG4771	TonB-dependent receptor
CWM47_RS22265	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS22270	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS22280	COG4206	TonB-dependent receptor
CWM47_RS22280	COG1629	transport
CWM47_RS22285	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS22305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWM47_RS22310	COG1247	-acetyltransferase
CWM47_RS22315	COG2226	methyltransferase
CWM47_RS22335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CWM47_RS22340	COG0247	lactate metabolic process
CWM47_RS22345	COG1139	Iron-sulfur cluster binding protein
CWM47_RS22350	COG1556	Lactate utilization protein
CWM47_RS22355	COG3279	Response regulator of the LytR AlgR family
CWM47_RS22360	COG3275	phosphorelay sensor kinase activity
CWM47_RS22370	COG0793	Belongs to the peptidase S41A family
CWM47_RS22375	COG0594	ribonuclease P activity
CWM47_RS22380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CWM47_RS22425	COG2814	Major facilitator Superfamily
CWM47_RS22450	COG2814	Major facilitator Superfamily
CWM47_RS22465	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWM47_RS22475	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWM47_RS22485	COG1678	Uncharacterized ACR, COG1678
CWM47_RS22520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CWM47_RS22525	COG4191	Histidine kinase
CWM47_RS22545	COG2382	esterase
CWM47_RS22545	COG3693	PFAM glycoside hydrolase, family 10
CWM47_RS22560	COG0556	nucleotide-excision repair
CWM47_RS22600	COG3664	PFAM glycoside hydrolase family 39
CWM47_RS22610	COG1629	transport
CWM47_RS22610	COG4206	TonB-dependent receptor
CWM47_RS22615	COG0702	epimerase
CWM47_RS22695	COG1607	acyl-coa hydrolase
CWM47_RS22710	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CWM47_RS22730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWM47_RS22730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWM47_RS22735	COG2354	Protein conserved in bacteria
CWM47_RS22745	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CWM47_RS22750	COG0604	alcohol dehydrogenase
CWM47_RS22805	COG2311	Membrane
CWM47_RS22825	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS22835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CWM47_RS22840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWM47_RS22855	COG0318	PFAM AMP-dependent synthetase and ligase
CWM47_RS22885	COG2130	NADP-dependent
CWM47_RS22925	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CWM47_RS22930	COG0673	inositol 2-dehydrogenase activity
CWM47_RS22960	COG0859	PFAM glycosyl transferase family 9
CWM47_RS22990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWM47_RS22995	COG0463	Glycosyl transferase, family 2
CWM47_RS23015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CWM47_RS23050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWM47_RS23055	COG1083	cytidylyl-transferase
CWM47_RS23060	COG0463	Glycosyl transferase, family 2
CWM47_RS23065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWM47_RS23070	COG0489	protein tyrosine kinase activity
CWM47_RS23090	COG1214	PFAM Peptidase M22, glycoprotease
CWM47_RS23095	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CWM47_RS23110	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CWM47_RS23115	COG1278	Cold shock
CWM47_RS23140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CWM47_RS23140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CWM47_RS23145	COG3118	belongs to the thioredoxin family
CWM47_RS23155	COG2942	2-epimerase
CWM47_RS23160	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CWM47_RS23160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWM47_RS23165	COG0277	FAD linked oxidase domain protein
CWM47_RS23200	COG0667	Aldo Keto reductase
CWM47_RS23215	COG1609	Transcriptional regulator
CWM47_RS23235	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWM47_RS23235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWM47_RS23240	COG0254	rRNA binding
CWM47_RS23285	COG0156	8-amino-7-oxononanoate synthase activity
CWM47_RS23290	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS23295	COG2197	response regulator
CWM47_RS23300	COG4585	Histidine kinase
CWM47_RS23315	COG0047	phosphoribosylformylglycinamidine synthase activity
CWM47_RS23320	COG1902	pentaerythritol trinitrate reductase activity
CWM47_RS23330	COG0693	protein deglycase activity
CWM47_RS23375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWM47_RS23385	COG1132	(ABC) transporter
CWM47_RS23390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWM47_RS23405	COG1862	Preprotein translocase
CWM47_RS23415	COG0237	dephospho-CoA kinase activity
CWM47_RS23430	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CWM47_RS23435	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CWM47_RS23440	COG3186	Phenylalanine-4-hydroxylase
CWM47_RS23460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWM47_RS23475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWM47_RS23485	COG2323	membrane
CWM47_RS23490	COG0366	Alpha amylase catalytic
CWM47_RS23555	COG0405	Gamma-glutamyltransferase
CWM47_RS23565	COG1733	regulation of RNA biosynthetic process
CWM47_RS23570	COG3239	Fatty acid desaturase
CWM47_RS23585	COG0366	Alpha amylase catalytic
CWM47_RS23625	COG2814	Major facilitator Superfamily
CWM47_RS23660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CWM47_RS23675	COG4654	Cytochrome c, class I
CWM47_RS23695	COG0726	polysaccharide deacetylase
CWM47_RS23735	COG1620	l-lactate permease
CWM47_RS23740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWM47_RS23750	COG1054	Belongs to the UPF0176 family
CWM47_RS23770	COG0673	inositol 2-dehydrogenase activity
CWM47_RS23810	COG1629	transport
CWM47_RS23815	COG0702	epimerase
CWM47_RS23850	COG2195	Cleaves the N-terminal amino acid of tripeptides
CWM47_RS23860	COG0768	penicillin binding
CWM47_RS23865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWM47_RS23870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWM47_RS23875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CWM47_RS23880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CWM47_RS23885	COG0052	Belongs to the universal ribosomal protein uS2 family
CWM47_RS23890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CWM47_RS23895	COG1595	DNA-templated transcription, initiation
CWM47_RS23905	COG0668	transmembrane transport
CWM47_RS23915	COG1970	mechanosensitive ion channel activity
CWM47_RS23920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CWM47_RS23925	COG0772	Belongs to the SEDS family
CWM47_RS23930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CWM47_RS23935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWM47_RS23950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CWM47_RS23960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWM47_RS23970	COG1629	transport
CWM47_RS23985	COG1473	amidohydrolase
CWM47_RS23990	COG2205	protein histidine kinase activity
CWM47_RS23990	COG0784	Response regulator, receiver
CWM47_RS24000	COG0538	isocitrate dehydrogenase activity
CWM47_RS24110	COG0745	RESPONSE REGULATOR receiver
CWM47_RS24110	COG2205	protein histidine kinase activity
CWM47_RS24110	COG3292	Two component regulator propeller
CWM47_RS24115	COG5002	protein histidine kinase activity
CWM47_RS24135	COG0784	Response regulator, receiver
CWM47_RS24140	COG4251	negative regulation of phosphorylation
CWM47_RS24185	COG2226	methyltransferase
CWM47_RS24205	COG0673	inositol 2-dehydrogenase activity
CWM47_RS24215	COG1078	dGTPase activity
CWM47_RS24220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CWM47_RS24225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CWM47_RS24225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CWM47_RS24230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CWM47_RS24235	COG1131	(ABC) transporter
CWM47_RS24245	COG4181	ATPase activity
CWM47_RS24265	COG1253	flavin adenine dinucleotide binding
CWM47_RS24270	COG1007	ATP synthesis coupled electron transport
CWM47_RS24275	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CWM47_RS24275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWM47_RS24280	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CWM47_RS24335	COG1132	(ABC) transporter
CWM47_RS24365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWM47_RS24375	COG0534	Mate efflux family protein
CWM47_RS24395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CWM47_RS24400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CWM47_RS24415	COG2197	response regulator
CWM47_RS24425	COG4771	TonB-dependent receptor
CWM47_RS24430	COG0561	phosphatase activity
CWM47_RS24460	COG4206	TonB-dependent receptor
CWM47_RS24490	COG0667	Aldo Keto reductase
CWM47_RS24500	COG0287	Prephenate dehydrogenase
CWM47_RS24510	COG0436	Aminotransferase
CWM47_RS24515	COG0494	nUDIX hydrolase
CWM47_RS24525	COG1957	nucleoside hydrolase
CWM47_RS24545	COG0604	alcohol dehydrogenase
CWM47_RS24545	COG3321	synthase
CWM47_RS24545	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS24555	COG0564	pseudouridine synthase activity
CWM47_RS24560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CWM47_RS24565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWM47_RS24580	COG0667	Aldo Keto reductase
CWM47_RS24605	COG1215	transferase activity, transferring glycosyl groups
CWM47_RS24615	COG0667	Aldo Keto reductase
CWM47_RS24620	COG0509	glycine decarboxylation via glycine cleavage system
CWM47_RS24625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWM47_RS24655	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CWM47_RS24690	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CWM47_RS24690	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CWM47_RS24695	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CWM47_RS24695	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CWM47_RS24700	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CWM47_RS24740	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS24750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CWM47_RS24760	COG0612	Peptidase, M16
CWM47_RS24770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWM47_RS24775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWM47_RS24795	COG0415	Belongs to the DNA photolyase family
CWM47_RS24825	COG0514	ATP-dependent DNA helicase (RecQ)
CWM47_RS24845	COG0018	arginyl-trna synthetase
CWM47_RS24850	COG0386	Belongs to the glutathione peroxidase family
CWM47_RS24855	COG1575	Belongs to the MenA family. Type 1 subfamily
CWM47_RS24870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CWM47_RS24885	COG0673	inositol 2-dehydrogenase activity
CWM47_RS24910	COG2204	response regulator
CWM47_RS24925	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CWM47_RS24945	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CWM47_RS24955	COG2205	protein histidine kinase activity
CWM47_RS24995	COG4251	negative regulation of phosphorylation
CWM47_RS25000	COG0606	chelatase, subunit chli
CWM47_RS25015	COG4771	TonB-dependent receptor
CWM47_RS25020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CWM47_RS25040	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CWM47_RS25055	COG1629	transport
CWM47_RS25060	COG4771	TonB-dependent receptor
CWM47_RS25080	COG1703	isobutyryl-CoA mutase activity
CWM47_RS25085	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CWM47_RS25090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CWM47_RS25130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CWM47_RS25165	COG3956	TIGRFAM MazG family protein
CWM47_RS25185	COG0516	GMP reductase activity
CWM47_RS25185	COG0517	IMP dehydrogenase activity
CWM47_RS25195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWM47_RS25195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CWM47_RS25200	COG1137	ATPase activity
CWM47_RS25210	COG4680	protein conserved in bacteria
CWM47_RS25215	COG1381	Involved in DNA repair and RecF pathway recombination
CWM47_RS25220	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWM47_RS25225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CWM47_RS25235	COG1136	(ABC) transporter
CWM47_RS25240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWM47_RS25255	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CWM47_RS25270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWM47_RS25285	COG0314	molybdopterin synthase activity
CWM47_RS25295	COG0779	Required for maturation of 30S ribosomal subunits
CWM47_RS25300	COG0195	Participates in both transcription termination and antitermination
CWM47_RS25305	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CWM47_RS25305	COG5180	pathogenesis
CWM47_RS25305	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CWM47_RS25305	COG5180	pathogenesis
CWM47_RS25330	COG0596	Alpha beta hydrolase
CWM47_RS25340	COG3591	Belongs to the peptidase S1B family
CWM47_RS25340	COG1864	DNA RNA non-specific endonuclease
CWM47_RS25455	COG3940	Belongs to the glycosyl hydrolase 43 family
CWM47_RS25490	COG0193	aminoacyl-tRNA hydrolase activity
CWM47_RS25520	COG2197	response regulator
CWM47_RS25525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWM47_RS25530	COG3158	transport of potassium into the cell
CWM47_RS25560	COG2815	serine threonine protein kinase
CWM47_RS25560	COG0515	serine threonine protein kinase
CWM47_RS25600	COG1321	iron dependent repressor
CWM47_RS25600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWM47_RS25650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWM47_RS25655	COG0714	Associated with various cellular activities
CWM47_RS25660	COG2890	protein-(glutamine-N5) methyltransferase activity
CWM47_RS25675	COG4206	TonB-dependent receptor
CWM47_RS25685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CWM47_RS25695	COG5002	protein histidine kinase activity
CWM47_RS25710	COG3250	beta-galactosidase activity
CWM47_RS25720	COG2217	Heavy metal translocating P-type atpase
CWM47_RS25725	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CWM47_RS25730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CWM47_RS25740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CWM47_RS25760	COG1082	Xylose isomerase domain protein TIM barrel
CWM47_RS25780	COG0180	Tryptophanyl-tRNA synthetase
CWM47_RS25785	COG0280	phosphate acetyltransferase
CWM47_RS25785	COG0281	malic enzyme
CWM47_RS25800	COG0406	alpha-ribazole phosphatase activity
CWM47_RS25805	COG3275	phosphorelay sensor kinase activity
CWM47_RS25810	COG3279	Response regulator of the LytR AlgR family
CWM47_RS25830	COG0686	Belongs to the AlaDH PNT family
CWM47_RS25835	COG1522	sequence-specific DNA binding
CWM47_RS25870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWM47_RS25875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWM47_RS25885	COG0745	RESPONSE REGULATOR receiver
CWM47_RS25890	COG5002	protein histidine kinase activity
CWM47_RS25920	COG0259	pyridoxamine-phosphate oxidase activity
CWM47_RS25955	COG3852	Histidine kinase
CWM47_RS25980	COG0456	acetyltransferase
CWM47_RS25985	COG0181	hydroxymethylbilane synthase activity
CWM47_RS26010	COG1629	transport
CWM47_RS26030	COG0584	glycerophosphoryl diester phosphodiesterase
CWM47_RS26040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWM47_RS26045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWM47_RS26080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWM47_RS26090	COG1053	succinate dehydrogenase
CWM47_RS26095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CWM47_RS26105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CWM47_RS26120	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CWM47_RS26125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CWM47_RS26130	COG1610	YqeY-like protein
CWM47_RS26140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CWM47_RS26145	COG0306	phosphate transporter
CWM47_RS26195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CWM47_RS26200	COG0805	protein transport
CWM47_RS26230	COG0714	Associated with various cellular activities
CWM47_RS26290	COG1119	ATPase activity
CWM47_RS26300	COG2885	chlorophyll binding
CWM47_RS26305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CWM47_RS26310	COG1845	cytochrome c oxidase, subunit III
CWM47_RS26320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWM47_RS26335	COG0653	protein targeting
CWM47_RS26375	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS26385	COG0463	Glycosyl transferase, family 2
CWM47_RS26410	COG5434	Belongs to the glycosyl hydrolase 28 family
CWM47_RS26440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWM47_RS26445	COG0657	acetylesterase activity
CWM47_RS26445	COG2755	lipolytic protein G-D-S-L family
CWM47_RS26460	COG0022	dehydrogenase e1 component
CWM47_RS26515	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWM47_RS26520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CWM47_RS26530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWM47_RS26560	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CWM47_RS26560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CWM47_RS26565	COG0251	oxidation-reduction process
CWM47_RS26615	COG0592	DNA-directed DNA polymerase activity
CWM47_RS26625	COG1131	(ABC) transporter
CWM47_RS26640	COG3258	Cytochrome c
CWM47_RS26650	COG0583	DNA-binding transcription factor activity
CWM47_RS26675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWM47_RS26680	COG1136	(ABC) transporter
CWM47_RS26695	COG1872	DUF167
CWM47_RS26700	COG3264	Mechanosensitive ion channel
CWM47_RS26700	COG1196	nuclear chromosome segregation
CWM47_RS26720	COG0463	Glycosyl transferase, family 2
CWM47_RS26745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CWM47_RS26765	COG0183	Belongs to the thiolase family
CWM47_RS26780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWM47_RS26795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWM47_RS26800	COG2197	response regulator
CWM47_RS26845	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CWM47_RS26850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWM47_RS26875	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CWM47_RS26880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWM47_RS26890	COG2169	Transcriptional regulator
CWM47_RS26910	COG0784	Response regulator, receiver
CWM47_RS26915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWM47_RS26935	COG0436	Aminotransferase
CWM47_RS26955	COG4206	TonB-dependent receptor
CWM47_RS26955	COG1629	transport
CWM47_RS26965	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CWM47_RS26980	COG0492	ferredoxin-NADP+ reductase activity
CWM47_RS27015	COG0470	DNA polymerase III
CWM47_RS27020	COG4067	protein conserved in archaea
CWM47_RS27020	COG0189	ligase activity
CWM47_RS27025	COG0189	ligase activity
CWM47_RS27045	COG1090	epimerase
CWM47_RS27050	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS27105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CWM47_RS27125	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CWM47_RS27130	COG1970	mechanosensitive ion channel activity
CWM47_RS27140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWM47_RS27155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWM47_RS27170	COG1595	DNA-templated transcription, initiation
CWM47_RS27180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWM47_RS27185	COG0105	UTP biosynthetic process
CWM47_RS27190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CWM47_RS27195	COG0545	Peptidyl-prolyl cis-trans isomerase
CWM47_RS27205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWM47_RS27220	COG3852	Histidine kinase
CWM47_RS27225	COG1309	transcriptional regulator
CWM47_RS27235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWM47_RS27255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CWM47_RS27275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWM47_RS27325	COG0629	single-stranded DNA binding
CWM47_RS27335	COG0776	regulation of translation
CWM47_RS27345	COG1530	ribonuclease E activity
CWM47_RS27355	COG3279	Response regulator of the LytR AlgR family
CWM47_RS27360	COG2197	response regulator
CWM47_RS27370	COG0358	DNA primase activity
CWM47_RS27405	COG1774	PSP1 C-terminal conserved region
CWM47_RS27410	COG0151	Belongs to the GarS family
CWM47_RS27425	COG1595	DNA-templated transcription, initiation
CWM47_RS27440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWM47_RS27445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWM47_RS27470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CWM47_RS27505	COG1007	ATP synthesis coupled electron transport
CWM47_RS27510	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWM47_RS27520	COG0713	ATP synthesis coupled electron transport
CWM47_RS27555	COG1063	alcohol dehydrogenase
CWM47_RS27560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWM47_RS27600	COG1956	GAF domain-containing protein
CWM47_RS27635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CWM47_RS27650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CWM47_RS27660	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CWM47_RS27665	COG0129	dihydroxy-acid dehydratase activity
CWM47_RS27670	COG0028	Belongs to the TPP enzyme family
CWM47_RS27680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CWM47_RS27685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWM47_RS27695	COG2361	Protein of unknown function DUF86
CWM47_RS27710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CWM47_RS27715	COG0066	3-isopropylmalate dehydratase activity
CWM47_RS27730	COG0473	3-isopropylmalate dehydrogenase activity
CWM47_RS27735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWM47_RS27960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWM47_RS27970	COG4221	oxidoreductase activity
CWM47_RS27975	COG3275	phosphorelay sensor kinase activity
CWM47_RS28035	COG4251	negative regulation of phosphorylation
CWM47_RS28050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CWM47_RS28075	COG5002	protein histidine kinase activity
CWM47_RS28080	COG0745	RESPONSE REGULATOR receiver
CWM47_RS28085	COG0038	chloride channel
CWM47_RS28090	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CWM47_RS28100	COG0038	chloride channel
CWM47_RS28130	COG2217	Heavy metal translocating P-type atpase
CWM47_RS28140	COG2814	Major facilitator Superfamily
CWM47_RS28190	COG0671	phosphoesterase, PA-phosphatase related
CWM47_RS28225	COG0671	phosphoesterase, PA-phosphatase related
CWM47_RS28285	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CWM47_RS28295	COG1431	PFAM Stem cell self-renewal protein Piwi
CWM47_RS28345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWM47_RS28355	COG0730	response to heat
CWM47_RS28360	COG3258	Cytochrome c
CWM47_RS28390	COG0583	DNA-binding transcription factor activity
CWM47_RS28395	COG2855	membrane
CWM47_RS28455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CWM47_RS28470	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS28480	COG0463	Glycosyl transferase, family 2
CWM47_RS28500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWM47_RS28615	COG4251	negative regulation of phosphorylation
CWM47_RS28620	COG0784	Response regulator, receiver
CWM47_RS28660	COG2201	protein-glutamate methylesterase activity
CWM47_RS28665	COG1473	amidohydrolase
CWM47_RS28670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CWM47_RS28685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWM47_RS28760	COG1472	Belongs to the glycosyl hydrolase 3 family
CWM47_RS28775	COG0024	Methionine aminopeptidase
CWM47_RS28790	COG0300	oxidoreductase activity
CWM47_RS28810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CWM47_RS28815	COG4771	TonB-dependent receptor
CWM47_RS28840	COG4771	TonB-dependent receptor
CWM47_RS28850	COG1629	transport
CWM47_RS28855	COG1752	Esterase of the alpha-beta hydrolase superfamily
CWM47_RS28860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWM47_RS28905	COG0298	carbon dioxide binding
CWM47_RS28910	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CWM47_RS28915	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CWM47_RS28950	COG1309	transcriptional regulator
CWM47_RS28970	COG1278	Cold shock
CWM47_RS28980	COG0745	RESPONSE REGULATOR receiver
CWM47_RS29010	COG0492	ferredoxin-NADP+ reductase activity
CWM47_RS29020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWM47_RS29045	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CWM47_RS29060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWM47_RS29090	COG0673	inositol 2-dehydrogenase activity
CWM47_RS29095	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS29125	COG0343	queuine tRNA-ribosyltransferase activity
CWM47_RS29135	COG0357	Ribosomal RNA small subunit methyltransferase G
CWM47_RS29225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CWM47_RS29225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CWM47_RS29235	COG3059	membrane
CWM47_RS29270	COG2267	carboxylic ester hydrolase activity
CWM47_RS29295	COG0477	Major facilitator Superfamily
CWM47_RS29300	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CWM47_RS29305	COG1309	transcriptional regulator
CWM47_RS29320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CWM47_RS29325	COG1160	GTP binding
CWM47_RS29335	COG2255	four-way junction helicase activity
CWM47_RS29360	COG0488	(ABC) transporter
CWM47_RS29410	COG0439	Biotin carboxylase
CWM47_RS29420	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CWM47_RS29425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWM47_RS29430	COG0416	fatty acid biosynthetic process
CWM47_RS29435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CWM47_RS29460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWM47_RS29460	COG1199	ATP-dependent helicase activity
CWM47_RS29470	COG1505	serine-type exopeptidase activity
CWM47_RS29480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWM47_RS29485	COG2326	polyphosphate kinase activity
CWM47_RS29490	COG2326	polyphosphate kinase activity
CWM47_RS29510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWM47_RS29515	COG0514	ATP-dependent DNA helicase (RecQ)
CWM47_RS29560	COG1217	gtp-binding protein TYPA
CWM47_RS29605	COG1595	DNA-templated transcription, initiation
CWM47_RS29635	COG0251	oxidation-reduction process
CWM47_RS29645	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CWM47_RS29645	COG0140	phosphoribosyl-ATP diphosphatase activity
CWM47_RS29650	COG0159	tryptophan synthase activity
CWM47_RS29655	COG0133	tryptophan synthase activity
CWM47_RS29660	COG0135	phosphoribosylanthranilate isomerase activity
CWM47_RS29665	COG0134	indole-3-glycerol-phosphate synthase activity
CWM47_RS29670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CWM47_RS29685	COG2945	thiolester hydrolase activity
CWM47_RS29685	COG0596	Alpha beta hydrolase
CWM47_RS29705	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS29720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWM47_RS29735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWM47_RS29740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWM47_RS29745	COG0346	lactoylglutathione lyase activity
CWM47_RS29765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWM47_RS29770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWM47_RS29775	COG1040	competence protein
CWM47_RS29790	COG0445	tRNA wobble uridine modification
CWM47_RS29795	COG2813	Specifically methylates the guanine in position
CWM47_RS29805	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CWM47_RS29810	COG1012	belongs to the aldehyde dehydrogenase family
CWM47_RS29815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CWM47_RS29820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CWM47_RS29830	COG2096	Adenosyltransferase
CWM47_RS29835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWM47_RS29855	COG1132	(ABC) transporter
CWM47_RS29860	COG1132	(ABC) transporter
CWM47_RS29880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWM47_RS29900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CWM47_RS29905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CWM47_RS29910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CWM47_RS29925	COG0702	epimerase
CWM47_RS29940	COG1960	acyl-CoA dehydrogenase activity
CWM47_RS29945	COG0429	hydrolase of the alpha beta-hydrolase fold
CWM47_RS29955	COG2361	Protein of unknown function DUF86
CWM47_RS29960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWM47_RS29995	COG1228	amidohydrolase
CWM47_RS30000	COG0596	Alpha beta hydrolase
CWM47_RS30005	COG1904	glucuronate isomerase
CWM47_RS30015	COG1312	Catalyzes the dehydration of D-mannonate
CWM47_RS30020	COG2271	Major facilitator Superfamily
CWM47_RS30030	COG0246	Mannitol dehydrogenase
CWM47_RS30040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWM47_RS30045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWM47_RS30065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWM47_RS30075	COG1129	ABC transporter
CWM47_RS30080	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWM47_RS30085	COG1879	ABC-type sugar transport system periplasmic component
CWM47_RS30105	COG1132	(ABC) transporter
CWM47_RS30110	COG5002	protein histidine kinase activity
CWM47_RS30115	COG0745	RESPONSE REGULATOR receiver
CWM47_RS30120	COG5002	protein histidine kinase activity
CWM47_RS30125	COG0745	RESPONSE REGULATOR receiver
CWM47_RS30130	COG4251	negative regulation of phosphorylation
CWM47_RS30135	COG2205	protein histidine kinase activity
CWM47_RS30135	COG5002	protein histidine kinase activity
CWM47_RS30135	COG0784	Response regulator, receiver
CWM47_RS30145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CWM47_RS30155	COG2205	protein histidine kinase activity
CWM47_RS30155	COG0784	Response regulator, receiver
CWM47_RS30160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CWM47_RS30215	COG0463	Glycosyl transferase, family 2
CWM47_RS30215	COG1216	Glycosyl transferase, family 2
CWM47_RS30220	COG0438	transferase activity, transferring glycosyl groups
CWM47_RS30240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CWM47_RS30250	COG1215	transferase activity, transferring glycosyl groups
CWM47_RS30255	COG4251	negative regulation of phosphorylation
CWM47_RS30260	COG1960	acyl-CoA dehydrogenase activity
CWM47_RS30275	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CWM47_RS30280	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CWM47_RS30290	COG1566	PFAM secretion protein HlyD family protein
CWM47_RS30295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWM47_RS30335	COG0753	catalase activity
CWM47_RS30340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWM47_RS30380	COG3485	protocatechuate 3,4-dioxygenase
CWM47_RS30435	COG0288	reversible hydration of carbon dioxide
CWM47_RS30450	COG0738	Major facilitator superfamily
CWM47_RS30465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWM47_RS30470	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CWM47_RS30475	COG2080	2 iron, 2 sulfur cluster binding
CWM47_RS30490	COG3254	rhamnose metabolic process
CWM47_RS30505	COG4952	isomerase
CWM47_RS30510	COG3347	Dehydrogenase
CWM47_RS30510	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS30525	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CWM47_RS30535	COG1074	ATP-dependent DNA helicase activity
CWM47_RS30545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWM47_RS30565	COG3279	Response regulator of the LytR AlgR family
CWM47_RS30585	COG2382	esterase
CWM47_RS30590	COG3275	phosphorelay sensor kinase activity
CWM47_RS30595	COG3279	Response regulator of the LytR AlgR family
CWM47_RS30650	COG4977	sequence-specific DNA binding
CWM47_RS30650	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS30670	COG0025	NhaP-type Na H and K H
CWM47_RS30680	COG3279	Response regulator of the LytR AlgR family
CWM47_RS30685	COG3275	phosphorelay sensor kinase activity
CWM47_RS30690	COG2272	Belongs to the type-B carboxylesterase lipase family
CWM47_RS30700	COG1104	cysteine desulfurase activity
CWM47_RS30705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CWM47_RS30710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CWM47_RS30715	COG0602	queuosine metabolic process
CWM47_RS30725	COG0492	ferredoxin-NADP+ reductase activity
CWM47_RS30730	COG0739	heme binding
CWM47_RS30745	COG0402	S-adenosylhomocysteine deaminase activity
CWM47_RS30750	COG1228	amidohydrolase
CWM47_RS30780	COG1309	transcriptional regulator
CWM47_RS30785	COG2353	YceI-like domain
CWM47_RS30790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CWM47_RS30800	COG2801	Transposase and inactivated derivatives
CWM47_RS30805	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CWM47_RS30810	COG1518	maintenance of DNA repeat elements
CWM47_RS30820	COG4804	nuclease activity
CWM47_RS30885	COG2197	response regulator
CWM47_RS30935	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS30955	COG2010	Cytochrome c
CWM47_RS30955	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CWM47_RS30960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWM47_RS30965	COG1845	cytochrome c oxidase, subunit III
CWM47_RS30980	COG0723	plastoquinol--plastocyanin reductase activity
CWM47_RS30985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CWM47_RS31075	COG0668	transmembrane transport
CWM47_RS31080	COG2323	membrane
CWM47_RS31130	COG0038	chloride channel
CWM47_RS31145	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS31220	COG1742	UPF0060 membrane protein
CWM47_RS31250	COG2226	methyltransferase
CWM47_RS31265	COG3485	protocatechuate 3,4-dioxygenase
CWM47_RS31270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWM47_RS31275	COG3279	Response regulator of the LytR AlgR family
CWM47_RS31280	COG3275	phosphorelay sensor kinase activity
CWM47_RS31410	COG2267	carboxylic ester hydrolase activity
CWM47_RS31445	COG0492	ferredoxin-NADP+ reductase activity
CWM47_RS31455	COG0745	RESPONSE REGULATOR receiver
CWM47_RS31455	COG2205	protein histidine kinase activity
CWM47_RS31455	COG3292	Two component regulator propeller
CWM47_RS31480	COG2382	esterase
CWM47_RS31510	COG0018	arginyl-trna synthetase
CWM47_RS31530	COG2972	Histidine kinase
CWM47_RS31535	COG3279	Response regulator of the LytR AlgR family
CWM47_RS31565	COG0577	efflux transmembrane transporter activity
CWM47_RS31600	COG0577	efflux transmembrane transporter activity
CWM47_RS31600	COG1136	(ABC) transporter
CWM47_RS31615	COG3275	phosphorelay sensor kinase activity
CWM47_RS31790	COG2755	lipolytic protein G-D-S-L family
CWM47_RS31790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWM47_RS31815	COG3279	Response regulator of the LytR AlgR family
CWM47_RS31835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWM47_RS31875	COG2226	methyltransferase
CWM47_RS31905	COG4977	sequence-specific DNA binding
CWM47_RS31910	COG4771	TonB-dependent receptor
CWM47_RS31915	COG0702	epimerase
CWM47_RS31925	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS31925	COG4977	sequence-specific DNA binding
CWM47_RS31960	COG1673	EVE domain
CWM47_RS32005	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS32065	COG1733	regulation of RNA biosynthetic process
CWM47_RS32105	COG0702	epimerase
CWM47_RS32130	COG1959	2 iron, 2 sulfur cluster binding
CWM47_RS32140	COG2814	Major facilitator Superfamily
CWM47_RS32145	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CWM47_RS32150	COG4106	trans-aconitate 2-methyltransferase activity
CWM47_RS32185	COG2801	Transposase and inactivated derivatives
CWM47_RS32215	COG1192	Involved in chromosome partitioning
CWM47_RS32260	COG3279	Response regulator of the LytR AlgR family
CWM47_RS32265	COG2972	Histidine kinase
CWM47_RS32335	COG3850	Histidine kinase
CWM47_RS32360	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CWM47_RS32440	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CWM47_RS32450	COG4702	Belongs to the UPF0303 family
CWM47_RS32490	COG2972	Histidine kinase
CWM47_RS32500	COG3279	Response regulator of the LytR AlgR family
CWM47_RS32515	COG0018	arginyl-trna synthetase
CWM47_RS32550	COG2855	membrane
CWM47_RS32580	COG2205	protein histidine kinase activity
CWM47_RS32580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWM47_RS32580	COG0784	Response regulator, receiver
CWM47_RS32580	COG2198	Histidine kinase
CWM47_RS32595	COG2801	Transposase and inactivated derivatives
CWM47_RS32600	COG2801	Transposase and inactivated derivatives
CWM47_RS32610	COG2963	transposase activity
CWM47_RS32635	COG0783	Belongs to the Dps family
CWM47_RS32640	COG1914	H( )-stimulated, divalent metal cation uptake system
CWM47_RS32670	COG0110	maltose O-acetyltransferase activity
CWM47_RS32680	COG0463	Glycosyl transferase, family 2
CWM47_RS32720	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CWM47_RS32730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CWM47_RS32745	COG1809	phosphosulfolactate synthase activity
CWM47_RS32750	COG0586	Pfam SNARE associated Golgi protein
CWM47_RS32755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CWM47_RS32795	COG0702	epimerase
CWM47_RS32800	COG4771	TonB-dependent receptor
CWM47_RS32810	COG2610	gluconate transmembrane transporter activity
CWM47_RS32815	COG1595	DNA-templated transcription, initiation
CWM47_RS32825	COG4771	TonB-dependent receptor
CWM47_RS32830	COG0702	epimerase
CWM47_RS32835	COG3940	Belongs to the glycosyl hydrolase 43 family
CWM47_RS32865	COG1629	transport
CWM47_RS32865	COG4206	TonB-dependent receptor
CWM47_RS32870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWM47_RS32875	COG0546	phosphoglycolate phosphatase activity
CWM47_RS32880	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CWM47_RS32885	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS32910	COG0217	transcriptional regulatory protein
CWM47_RS32915	COG0019	diaminopimelate decarboxylase activity
CWM47_RS32925	COG0363	glucosamine-6-phosphate deaminase activity
CWM47_RS32930	COG2252	PERMEase
CWM47_RS32935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWM47_RS32960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWM47_RS32965	COG2873	o-acetylhomoserine
CWM47_RS33010	COG3279	Response regulator of the LytR AlgR family
CWM47_RS33020	COG0463	Glycosyl transferase, family 2
CWM47_RS33035	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWM47_RS33040	COG0300	oxidoreductase activity
CWM47_RS33045	COG1473	amidohydrolase
CWM47_RS33050	COG4206	TonB-dependent receptor
CWM47_RS33050	COG1629	transport
CWM47_RS33065	COG4771	TonB-dependent receptor
CWM47_RS33075	COG1404	Belongs to the peptidase S8 family
CWM47_RS33080	COG1028	Short-chain dehydrogenase reductase Sdr
CWM47_RS33095	COG2801	Transposase and inactivated derivatives
CWM47_RS33105	COG5002	protein histidine kinase activity
CWM47_RS33145	COG0784	Response regulator, receiver
CWM47_RS33170	COG4771	TonB-dependent receptor
CWM47_RS33175	COG0702	epimerase
CWM47_RS33200	COG0628	permease
CWM47_RS33225	COG1295	ribonuclease BN
CWM47_RS33270	COG1192	Involved in chromosome partitioning
CWM47_RS33390	COG0287	Prephenate dehydrogenase
CWM47_RS33390	COG1605	Chorismate mutase
CWM47_RS33405	COG0246	Mannitol dehydrogenase
CWM47_RS33410	COG0738	Major facilitator superfamily
CWM47_RS33420	COG2201	protein-glutamate methylesterase activity
CWM47_RS33435	COG2801	Transposase and inactivated derivatives
CWM47_RS33490	COG0745	RESPONSE REGULATOR receiver
CWM47_RS33495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CWM47_RS33505	COG4251	negative regulation of phosphorylation
CWM47_RS33515	COG0784	Response regulator, receiver
CWM47_RS33515	COG0835	chemotaxis
CWM47_RS33520	COG4251	negative regulation of phosphorylation
CWM47_RS33525	COG3852	Histidine kinase
CWM47_RS33555	COG4771	TonB-dependent receptor
CWM47_RS33560	COG0702	epimerase
CWM47_RS33575	COG1175	transmembrane transport
CWM47_RS33580	COG0395	ABC-type sugar transport system, permease component
CWM47_RS33590	COG3842	ATPase activity
CWM47_RS33605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWM47_RS33625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWM47_RS33630	COG0113	porphobilinogen synthase activity
CWM47_RS33680	COG2270	Major facilitator Superfamily
CWM47_RS33700	COG1331	Highly conserved protein containing a thioredoxin domain
CWM47_RS33720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CWM47_RS33730	COG0463	Glycosyl transferase, family 2
CWM47_RS33740	COG1215	transferase activity, transferring glycosyl groups
CWM47_RS33745	COG0084	hydrolase, TatD family'
CWM47_RS33750	COG0252	asparaginase activity
CWM47_RS33765	COG2154	pterin-4-alpha-carbinolamine dehydratase
CWM47_RS33770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CWM47_RS33780	COG3458	cephalosporin-C deacetylase activity
CWM47_RS33800	COG2949	membrane
CWM47_RS33820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CWM47_RS33820	COG0116	Belongs to the methyltransferase superfamily
CWM47_RS33830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CWM47_RS33835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CWM47_RS33840	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CWM47_RS33845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CWM47_RS33865	COG0443	Heat shock 70 kDa protein
CWM47_RS33895	COG0531	amino acid
CWM47_RS33905	COG4948	Mandelate Racemase Muconate Lactonizing
CWM47_RS33915	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CWM47_RS34035	COG0463	Glycosyl transferase, family 2
CWM47_RS34045	COG2133	pyrroloquinoline quinone binding
CWM47_RS34075	COG2801	Transposase and inactivated derivatives
CWM47_RS34180	COG0739	heme binding
CWM47_RS34315	COG3590	peptidase
CWM47_RS34335	COG4804	nuclease activity
CWM47_RS34410	COG0489	protein tyrosine kinase activity
CWM47_RS34460	COG0484	heat shock protein binding
CWM47_RS34485	COG0739	heme binding
CWM47_RS34525	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CWM47_RS34545	COG2235	arginine
CWM47_RS34565	COG0396	ATPase activity
CWM47_RS34570	COG0719	Fe-S assembly protein
CWM47_RS34580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWM47_RS34600	COG2151	metal-sulfur cluster biosynthetic enzyme
CWM47_RS34610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CWM47_RS34645	COG4974	Belongs to the 'phage' integrase family
CWM47_RS34650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CWM47_RS34655	COG0248	Ppx GppA phosphatase
CWM47_RS34700	COG4221	oxidoreductase activity
CWM47_RS34765	COG4251	negative regulation of phosphorylation
CWM47_RS34770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWM47_RS34770	COG2755	lipolytic protein G-D-S-L family
CWM47_RS34785	COG0798	PFAM Bile acid sodium symporter
CWM47_RS34795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWM47_RS34800	COG2226	methyltransferase
CWM47_RS34820	COG1858	cytochrome C peroxidase
CWM47_RS34835	COG1858	cytochrome C peroxidase
CWM47_RS34850	COG4771	TonB-dependent receptor
CWM47_RS34890	COG1858	cytochrome C peroxidase
CWM47_RS34960	COG3548	integral membrane protein
CWM47_RS34980	COG0604	alcohol dehydrogenase
CWM47_RS34990	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS34990	COG4977	sequence-specific DNA binding
CWM47_RS35010	COG4221	oxidoreductase activity
CWM47_RS35020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWM47_RS35025	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CWM47_RS35030	COG2080	2 iron, 2 sulfur cluster binding
CWM47_RS35075	COG2198	Histidine kinase
CWM47_RS35075	COG0784	Response regulator, receiver
CWM47_RS35075	COG0643	Histidine kinase
CWM47_RS35095	COG1741	Belongs to the pirin family
CWM47_RS35105	COG1484	DNA-dependent DNA replication
CWM47_RS35110	COG2801	Transposase and inactivated derivatives
CWM47_RS35130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CWM47_RS35145	COG1278	Cold shock
CWM47_RS35230	COG5002	protein histidine kinase activity
CWM47_RS35230	COG2205	protein histidine kinase activity
CWM47_RS35230	COG0784	Response regulator, receiver
CWM47_RS35310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWM47_RS35320	COG3920	Histidine kinase
CWM47_RS35350	COG2207	Transcriptional regulator
CWM47_RS35350	COG1917	Cupin 2, conserved barrel domain protein
CWM47_RS35355	COG1073	alpha beta
CWM47_RS35385	COG4771	TonB-dependent receptor
CWM47_RS35420	COG4251	negative regulation of phosphorylation
CWM47_RS35425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWM47_RS35440	COG0657	acetylesterase activity
CWM47_RS35455	COG0159	tryptophan synthase activity
CWM47_RS35460	COG0133	tryptophan synthase activity
CWM47_RS35500	COG4771	TonB-dependent receptor
CWM47_RS35540	COG2801	Transposase and inactivated derivatives
CWM47_RS35550	COG4974	Belongs to the 'phage' integrase family
CWM47_RS35555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CWM47_RS35565	COG1132	(ABC) transporter
CWM47_RS35580	COG0107	imidazoleglycerol-phosphate synthase activity
CWM47_RS35595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CWM47_RS35610	COG0525	valine-tRNA ligase activity
CWM47_RS35630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWM47_RS35640	COG3537	Alpha-1,2-mannosidase
CWM47_RS35690	COG0156	8-amino-7-oxononanoate synthase activity
CWM47_RS35700	COG4804	nuclease activity
CWM47_RS35730	COG1203	CRISPR-associated helicase, Cas3
CWM47_RS35745	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CWM47_RS35830	COG1295	ribonuclease BN
CWM47_RS35890	COG2801	Transposase and inactivated derivatives
CWM47_RS35910	COG1278	Cold shock
CWM47_RS35920	COG1228	amidohydrolase
CWM47_RS35960	COG4584	PFAM Integrase catalytic
CWM47_RS35985	COG0776	regulation of translation
CWM47_RS36000	COG2201	protein-glutamate methylesterase activity
CWM47_RS36070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWM47_RS36205	COG2201	protein-glutamate methylesterase activity
CWM47_RS36240	COG1595	DNA-templated transcription, initiation
CWM47_RS36300	COG2801	Transposase and inactivated derivatives
CWM47_RS36330	COG1216	Glycosyl transferase, family 2
CWM47_RS36340	COG0745	RESPONSE REGULATOR receiver
CWM47_RS36350	COG0745	RESPONSE REGULATOR receiver
CWM47_RS36360	COG1595	DNA-templated transcription, initiation
CWM47_RS36365	COG4251	negative regulation of phosphorylation
CWM47_RS36425	COG1215	transferase activity, transferring glycosyl groups
CWM47_RS36440	COG4251	negative regulation of phosphorylation
CWM47_RS36465	COG1629	transport
CWM47_RS36475	COG3250	beta-galactosidase activity
CWM47_RS36495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CWM47_RS36515	COG3158	transport of potassium into the cell
CWM47_RS36625	COG1216	Glycosyl transferase, family 2
CWM47_RS36705	COG1082	Xylose isomerase domain protein TIM barrel
CWM47_RS36720	COG0745	RESPONSE REGULATOR receiver
CWM47_RS36725	COG5002	protein histidine kinase activity
CWM47_RS36730	COG4774	siderophore transport
CWM47_RS36740	COG3344	reverse transcriptase
CWM47_RS36895	COG2201	protein-glutamate methylesterase activity
CWM47_RS36930	COG3275	phosphorelay sensor kinase activity
CWM47_RS36940	COG2801	Transposase and inactivated derivatives
CWM47_RS37010	COG0784	Response regulator, receiver
CWM47_RS37035	COG0489	protein tyrosine kinase activity
CWM47_RS37035	COG3206	protein involved in exopolysaccharide biosynthesis
CWM47_RS37040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWM47_RS37050	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CWM47_RS37060	COG1484	DNA-dependent DNA replication
CWM47_RS37110	COG3852	Histidine kinase
CWM47_RS37435	COG0745	RESPONSE REGULATOR receiver
CWM47_RS37445	COG0745	RESPONSE REGULATOR receiver
CWM47_RS37450	COG4251	negative regulation of phosphorylation
CWM47_RS37620	COG0784	Response regulator, receiver
CWM47_RS37900	COG0326	Molecular chaperone. Has ATPase activity