locus-tag	class	description
SporoP8_RS00005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SporoP8_RS00015	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS00025	COG2384	SAM-dependent methyltransferase
SporoP8_RS00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SporoP8_RS00045	COG0513	Belongs to the DEAD box helicase family
SporoP8_RS00060	COG1121	(ABC) transporter
SporoP8_RS00065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SporoP8_RS00070	COG0735	belongs to the Fur family
SporoP8_RS00075	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
SporoP8_RS00080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SporoP8_RS00095	COG1283	sodium-dependent phosphate transmembrane transporter activity
SporoP8_RS00100	COG2839	Protein conserved in bacteria
SporoP8_RS00110	COG0768	penicillin binding
SporoP8_RS00125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SporoP8_RS00130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SporoP8_RS00140	COG1368	sulfuric ester hydrolase activity
SporoP8_RS00155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SporoP8_RS00165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SporoP8_RS00170	COG1459	type II secretion system
SporoP8_RS00175	COG4537	Required for transformation and DNA binding
SporoP8_RS00180	COG4969	Belongs to the N-Me-Phe pilin family
SporoP8_RS00200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SporoP8_RS00205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SporoP8_RS00230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SporoP8_RS00235	COG2610	gluconate transmembrane transporter activity
SporoP8_RS00240	COG0753	catalase activity
SporoP8_RS00275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SporoP8_RS00280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SporoP8_RS00290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SporoP8_RS00295	COG1966	Carbon starvation protein
SporoP8_RS00300	COG3872	metal-dependent enzyme
SporoP8_RS00310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SporoP8_RS00315	COG0006	proline dipeptidase activity
SporoP8_RS00350	COG0511	ligase activity, forming carbon-carbon bonds
SporoP8_RS00355	COG0439	Biotin carboxylase
SporoP8_RS00360	COG1302	Protein conserved in bacteria
SporoP8_RS00380	COG1722	exodeoxyribonuclease VII activity
SporoP8_RS00385	COG0142	geranyltranstransferase activity
SporoP8_RS00390	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SporoP8_RS00395	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SporoP8_RS00400	COG1438	arginine binding
SporoP8_RS00405	COG0497	DNA recombination
SporoP8_RS00410	COG0750	zinc metalloprotease
SporoP8_RS00425	COG0584	glycerophosphoryl diester phosphodiesterase
SporoP8_RS00440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SporoP8_RS00445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SporoP8_RS00450	COG0022	dehydrogenase e1 component
SporoP8_RS00455	COG0508	dehydrogenase complex catalyzes the overall conversion of
SporoP8_RS00465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SporoP8_RS00465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SporoP8_RS00470	COG1703	isobutyryl-CoA mutase activity
SporoP8_RS00480	COG0346	lactoylglutathione lyase activity
SporoP8_RS00485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SporoP8_RS00490	COG2195	Cleaves the N-terminal amino acid of tripeptides
SporoP8_RS00510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SporoP8_RS00520	COG4260	virion core protein, lumpy skin disease virus
SporoP8_RS00525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SporoP8_RS00530	COG0300	oxidoreductase activity
SporoP8_RS00540	COG5002	protein histidine kinase activity
SporoP8_RS00560	COG1187	pseudouridine synthase activity
SporoP8_RS00585	COG0640	Transcriptional regulator
SporoP8_RS00595	COG1278	Cold shock
SporoP8_RS00610	COG1114	Component of the transport system for branched-chain amino acids
SporoP8_RS00620	COG1725	Transcriptional regulator
SporoP8_RS00625	COG1131	(ABC) transporter
SporoP8_RS00640	COG1595	DNA-templated transcription, initiation
SporoP8_RS00665	COG0477	Major facilitator Superfamily
SporoP8_RS00680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SporoP8_RS00685	COG0765	amino acid transport
SporoP8_RS00690	COG1126	abc transporter atp-binding protein
SporoP8_RS00695	COG0753	catalase activity
SporoP8_RS00715	COG3832	glyoxalase III activity
SporoP8_RS00725	COG0628	permease
SporoP8_RS00770	COG1966	Carbon starvation protein
SporoP8_RS00790	COG3871	stress protein (general stress protein 26)
SporoP8_RS00795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SporoP8_RS00800	COG1132	(ABC) transporter
SporoP8_RS00805	COG1132	(ABC) transporter
SporoP8_RS00810	COG0785	Cytochrome C biogenesis protein
SporoP8_RS00820	COG4846	Membrane protein involved in cytochrome C biogenesis
SporoP8_RS00845	COG1999	signal sequence binding
SporoP8_RS00860	COG1335	isochorismatase
SporoP8_RS00865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SporoP8_RS00870	COG0824	Thioesterase
SporoP8_RS00880	COG4841	protein insertion into membrane
SporoP8_RS00885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SporoP8_RS00890	COG0187	DNA topoisomerase II activity
SporoP8_RS00895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SporoP8_RS00900	COG0045	succinate-CoA ligase (ADP-forming) activity
SporoP8_RS00900	COG1042	CoA-binding domain protein
SporoP8_RS00900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SporoP8_RS00905	COG2030	dehydratase
SporoP8_RS00925	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS00935	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS00945	COG2086	electron transfer activity
SporoP8_RS00950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SporoP8_RS00965	COG1304	FMN binding
SporoP8_RS00970	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SporoP8_RS00975	COG4149	molybdate abc transporter
SporoP8_RS00980	COG0725	ABC transporter, periplasmic molybdate-binding protein
SporoP8_RS00985	COG1910	domain protein
SporoP8_RS00990	COG0628	permease
SporoP8_RS01000	COG2807	transmembrane transport
SporoP8_RS01005	COG0488	(ABC) transporter
SporoP8_RS01020	COG1278	Cold shock
SporoP8_RS01035	COG3853	Toxic anion resistance protein (TelA)
SporoP8_RS01045	COG0508	dehydrogenase complex catalyzes the overall conversion of
SporoP8_RS01050	COG0567	Dehydrogenase, E1 component
SporoP8_RS01060	COG0534	Mate efflux family protein
SporoP8_RS01065	COG2340	Cysteine-rich secretory protein family
SporoP8_RS01070	COG0523	cobalamin synthesis protein
SporoP8_RS01075	COG3409	Peptidoglycan-binding domain 1 protein
SporoP8_RS01075	COG0793	Belongs to the peptidase S41A family
SporoP8_RS01080	COG0813	purine-nucleoside phosphorylase activity
SporoP8_RS01085	COG4479	Belongs to the UPF0346 family
SporoP8_RS01105	COG2755	lipolytic protein G-D-S-L family
SporoP8_RS01110	COG1307	EDD domain protein, DegV family
SporoP8_RS01115	COG1272	protein, Hemolysin III
SporoP8_RS01120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SporoP8_RS01135	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SporoP8_RS01150	COG2521	methyltransferase
SporoP8_RS01150	COG2136	Putative SAM-dependent methyltransferase
SporoP8_RS01160	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS01165	COG1268	BioY protein
SporoP8_RS01170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SporoP8_RS01175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SporoP8_RS01185	COG0405	Gamma-glutamyltransferase
SporoP8_RS01195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SporoP8_RS01210	COG1067	ATP-dependent peptidase activity
SporoP8_RS01230	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SporoP8_RS01250	COG4122	O-methyltransferase activity
SporoP8_RS01260	COG0444	Belongs to the ABC transporter superfamily
SporoP8_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SporoP8_RS01270	COG0601	transmembrane transport
SporoP8_RS01280	COG4413	Urea transporter
SporoP8_RS01285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SporoP8_RS01295	COG1132	(ABC) transporter
SporoP8_RS01305	COG1388	LysM domain
SporoP8_RS01310	COG3850	Histidine kinase
SporoP8_RS01310	COG5002	protein histidine kinase activity
SporoP8_RS01315	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS01335	COG2271	Major facilitator Superfamily
SporoP8_RS01340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SporoP8_RS01345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SporoP8_RS01375	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
SporoP8_RS01380	COG4638	Rieske (2fe-2S)
SporoP8_RS01395	COG0028	Belongs to the TPP enzyme family
SporoP8_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS01410	COG1414	Transcriptional regulator
SporoP8_RS01425	COG1013	pyruvate-flavodoxin oxidoreductase activity
SporoP8_RS01430	COG0674	pyruvate-flavodoxin oxidoreductase activity
SporoP8_RS01430	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SporoP8_RS01435	COG0492	ferredoxin-NADP+ reductase activity
SporoP8_RS01445	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS01455	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SporoP8_RS01480	COG0640	Transcriptional regulator
SporoP8_RS01490	COG1525	nuclease
SporoP8_RS01500	COG0477	Major facilitator Superfamily
SporoP8_RS01505	COG2986	histidine ammonia-lyase
SporoP8_RS01510	COG2056	Na+-H+ antiporter family
SporoP8_RS01515	COG2195	Cleaves the N-terminal amino acid of tripeptides
SporoP8_RS01520	COG1228	amidohydrolase
SporoP8_RS01525	COG3314	Sporulation integral membrane protein YlbJ
SporoP8_RS01530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SporoP8_RS01535	COG3829	transcription factor binding
SporoP8_RS01555	COG4085	toxin activity
SporoP8_RS01555	COG1525	nuclease
SporoP8_RS01555	COG0737	Belongs to the 5'-nucleotidase family
SporoP8_RS01560	COG2186	Transcriptional regulator
SporoP8_RS01570	COG5646	InterPro IPR014922
SporoP8_RS01620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SporoP8_RS01625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SporoP8_RS01635	COG0842	Transport permease protein
SporoP8_RS01640	COG1131	(ABC) transporter
SporoP8_RS01645	COG0697	spore germination
SporoP8_RS01670	COG0305	Participates in initiation and elongation during chromosome replication
SporoP8_RS01695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SporoP8_RS01700	COG0247	lactate metabolic process
SporoP8_RS01705	COG0277	FAD linked oxidase domain protein
SporoP8_RS01710	COG1984	allophanate hydrolase subunit 2
SporoP8_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS01740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SporoP8_RS01755	COG0028	Belongs to the TPP enzyme family
SporoP8_RS01760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SporoP8_RS01765	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS01770	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SporoP8_RS01775	COG1515	deoxyribonuclease V activity
SporoP8_RS01795	COG0346	lactoylglutathione lyase activity
SporoP8_RS01805	COG2264	protein methyltransferase activity
SporoP8_RS01810	COG1201	RNA secondary structure unwinding
SporoP8_RS01850	COG0714	Associated with various cellular activities
SporoP8_RS01915	COG1131	(ABC) transporter
SporoP8_RS01950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SporoP8_RS01955	COG2390	Transcriptional regulator
SporoP8_RS02005	COG0506	proline dehydrogenase activity
SporoP8_RS02015	COG0322	excinuclease ABC activity
SporoP8_RS02025	COG0840	transmembrane signaling receptor activity
SporoP8_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS02075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SporoP8_RS02085	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS02090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SporoP8_RS02100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SporoP8_RS02110	COG1490	D-aminoacyl-tRNA deacylase activity
SporoP8_RS02115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SporoP8_RS02125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SporoP8_RS02125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SporoP8_RS02135	COG5416	Lipopolysaccharide assembly protein A domain
SporoP8_RS02140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SporoP8_RS02140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SporoP8_RS02150	COG2244	polysaccharide biosynthetic process
SporoP8_RS02155	COG2323	membrane
SporoP8_RS02160	COG1862	Preprotein translocase
SporoP8_RS02165	COG0343	queuine tRNA-ribosyltransferase activity
SporoP8_RS02220	COG2329	Antibiotic biosynthesis monooxygenase
SporoP8_RS02225	COG0217	transcriptional regulatory protein
SporoP8_RS02240	COG0077	Prephenate dehydratase
SporoP8_RS02260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SporoP8_RS02265	COG2868	ribosomal protein
SporoP8_RS02285	COG2894	cell division
SporoP8_RS02290	COG0850	regulation of cytokinetic process
SporoP8_RS02300	COG1792	Involved in formation and maintenance of cell shape
SporoP8_RS02305	COG1077	Cell shape determining protein MreB Mrl
SporoP8_RS02310	COG2003	Belongs to the UPF0758 family
SporoP8_RS02325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SporoP8_RS02350	COG1459	type II secretion system
SporoP8_RS02360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SporoP8_RS02385	COG0285	dihydrofolate synthase activity
SporoP8_RS02390	COG0189	ligase activity
SporoP8_RS02400	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SporoP8_RS02405	COG0412	Dienelactone hydrolase
SporoP8_RS02415	COG1619	proteins homologs of microcin C7 resistance protein MccF
SporoP8_RS02420	COG2264	protein methyltransferase activity
SporoP8_RS02440	COG0525	valine-tRNA ligase activity
SporoP8_RS02455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SporoP8_RS02460	COG0113	porphobilinogen synthase activity
SporoP8_RS02465	COG1587	Uroporphyrinogen-III synthase
SporoP8_RS02475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SporoP8_RS02495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SporoP8_RS02500	COG0544	peptidyl-prolyl cis-trans isomerase activity
SporoP8_RS02505	COG0457	Tetratricopeptide repeat
SporoP8_RS02505	COG1477	protein flavinylation
SporoP8_RS02510	COG1597	lipid kinase activity
SporoP8_RS02525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SporoP8_RS02540	COG1418	mRNA catabolic process
SporoP8_RS02545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SporoP8_RS02545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SporoP8_RS02550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS02555	COG3339	Conserved Protein
SporoP8_RS02565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SporoP8_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS02585	COG1024	Enoyl-CoA hydratase
SporoP8_RS02590	COG1024	Enoyl-CoA hydratase
SporoP8_RS02595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SporoP8_RS02605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SporoP8_RS02610	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS02635	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS02650	COG0477	Major facilitator Superfamily
SporoP8_RS02675	COG0861	Integral membrane protein TerC family
SporoP8_RS02690	COG3655	Transcriptional regulator
SporoP8_RS02720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SporoP8_RS02725	COG1024	Enoyl-CoA hydratase
SporoP8_RS02730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SporoP8_RS02735	COG0511	ligase activity, forming carbon-carbon bonds
SporoP8_RS02740	COG0439	Biotin carboxylase
SporoP8_RS02745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SporoP8_RS02750	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS02755	COG3835	regulator
SporoP8_RS02785	COG1024	Enoyl-CoA hydratase
SporoP8_RS02790	COG0183	Belongs to the thiolase family
SporoP8_RS02795	COG0318	PFAM AMP-dependent synthetase and ligase
SporoP8_RS02805	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS02815	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS02820	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS02820	COG2030	dehydratase
SporoP8_RS02835	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS02840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SporoP8_RS02840	COG2508	Transcriptional regulator
SporoP8_RS02855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SporoP8_RS02880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SporoP8_RS02890	COG1846	Transcriptional regulator
SporoP8_RS02895	COG2197	response regulator
SporoP8_RS02900	COG0824	Thioesterase
SporoP8_RS02905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SporoP8_RS02910	COG1053	succinate dehydrogenase
SporoP8_RS02915	COG2009	succinate dehydrogenase
SporoP8_RS02925	COG3118	belongs to the thioredoxin family
SporoP8_RS02930	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SporoP8_RS02935	COG2086	electron transfer activity
SporoP8_RS02940	COG1024	Enoyl-CoA hydratase
SporoP8_RS02945	COG1309	transcriptional regulator
SporoP8_RS02950	COG0318	PFAM AMP-dependent synthetase and ligase
SporoP8_RS02955	COG3766	membrane
SporoP8_RS02960	COG1193	negative regulation of DNA recombination
SporoP8_RS02965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SporoP8_RS02965	COG1796	DNA polymerase
SporoP8_RS02985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SporoP8_RS02985	COG0072	phenylalanine-tRNA ligase activity
SporoP8_RS02995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SporoP8_RS03005	COG0318	PFAM AMP-dependent synthetase and ligase
SporoP8_RS03015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SporoP8_RS03020	COG1363	Peptidase, m42
SporoP8_RS03035	COG0514	ATP-dependent DNA helicase (RecQ)
SporoP8_RS03050	COG0688	phosphatidylethanolamine metabolic process
SporoP8_RS03055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SporoP8_RS03075	COG0753	catalase activity
SporoP8_RS03085	COG0726	polysaccharide deacetylase
SporoP8_RS03090	COG1054	Belongs to the UPF0176 family
SporoP8_RS03095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SporoP8_RS03105	COG0581	inorganic phosphate transmembrane transporter activity
SporoP8_RS03110	COG0573	inorganic phosphate transmembrane transporter activity
SporoP8_RS03115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SporoP8_RS03120	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS03125	COG2130	NADP-dependent
SporoP8_RS03130	COG0492	ferredoxin-NADP+ reductase activity
SporoP8_RS03145	COG2199	diguanylate cyclase activity
SporoP8_RS03145	COG2203	Gaf domain
SporoP8_RS03150	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SporoP8_RS03155	COG0604	alcohol dehydrogenase
SporoP8_RS03185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SporoP8_RS03190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SporoP8_RS03195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SporoP8_RS03200	COG1484	DNA-dependent DNA replication
SporoP8_RS03205	COG3611	Membrane attachment protein
SporoP8_RS03210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SporoP8_RS03215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SporoP8_RS03225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SporoP8_RS03230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SporoP8_RS03230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SporoP8_RS03235	COG0330	HflC and HflK could
SporoP8_RS03240	COG0330	HflC and HflK could
SporoP8_RS03245	COG5002	protein histidine kinase activity
SporoP8_RS03250	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS03265	COG0538	isocitrate dehydrogenase activity
SporoP8_RS03270	COG0372	Belongs to the citrate synthase family
SporoP8_RS03275	COG0628	permease
SporoP8_RS03280	COG3030	protein affecting phage T7 exclusion by the F plasmid
SporoP8_RS03295	COG0825	malonyl-CoA metabolic process
SporoP8_RS03305	COG2186	Transcriptional regulator
SporoP8_RS03310	COG0587	DNA-directed DNA polymerase activity
SporoP8_RS03315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SporoP8_RS03325	COG4109	DRTGG domain
SporoP8_RS03335	COG0006	proline dipeptidase activity
SporoP8_RS03340	COG0686	Belongs to the AlaDH PNT family
SporoP8_RS03345	COG0589	response to stress
SporoP8_RS03355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SporoP8_RS03360	COG0827	DNA restriction-modification system
SporoP8_RS03365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SporoP8_RS03370	COG1714	RDD family
SporoP8_RS03375	COG0616	signal peptide processing
SporoP8_RS03380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SporoP8_RS03385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SporoP8_RS03400	COG1104	cysteine desulfurase activity
SporoP8_RS03405	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SporoP8_RS03410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SporoP8_RS03420	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SporoP8_RS03430	COG0626	cystathionine gamma-synthase activity
SporoP8_RS03500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SporoP8_RS03510	COG0454	-acetyltransferase
SporoP8_RS03515	COG0517	IMP dehydrogenase activity
SporoP8_RS03525	COG1609	Transcriptional regulator
SporoP8_RS03530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SporoP8_RS03530	COG1605	Chorismate mutase
SporoP8_RS03535	COG0849	cell division
SporoP8_RS03540	COG4980	gas vesicle protein
SporoP8_RS03550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SporoP8_RS03555	COG1674	ftsk spoiiie
SporoP8_RS03560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SporoP8_RS03565	COG4848	Belongs to the UPF0354 family
SporoP8_RS03575	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
SporoP8_RS03580	COG1363	Peptidase, m42
SporoP8_RS03585	COG5584	Small secreted protein
SporoP8_RS03590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SporoP8_RS03610	COG1349	DNA-binding transcription factor activity
SporoP8_RS03615	COG1187	pseudouridine synthase activity
SporoP8_RS03620	COG2244	polysaccharide biosynthetic process
SporoP8_RS03625	COG2081	HI0933 family
SporoP8_RS03635	COG1242	4 iron, 4 sulfur cluster binding
SporoP8_RS03640	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SporoP8_RS03645	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS03655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SporoP8_RS03655	COG0517	IMP dehydrogenase activity
SporoP8_RS03660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SporoP8_RS03665	COG3162	membrane
SporoP8_RS03670	COG1802	Transcriptional regulator
SporoP8_RS03680	COG1114	Component of the transport system for branched-chain amino acids
SporoP8_RS03690	COG0420	3'-5' exonuclease activity
SporoP8_RS03695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SporoP8_RS03710	COG1116	anion transmembrane transporter activity
SporoP8_RS03715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SporoP8_RS03720	COG2223	nitrite transmembrane transporter activity
SporoP8_RS03735	COG1164	Oligoendopeptidase f
SporoP8_RS03740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SporoP8_RS03745	COG1733	regulation of RNA biosynthetic process
SporoP8_RS03750	COG0778	Nitroreductase
SporoP8_RS03755	COG0351	phosphomethylpyrimidine kinase
SporoP8_RS03770	COG2226	methyltransferase
SporoP8_RS03790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SporoP8_RS03790	COG2755	lipolytic protein G-D-S-L family
SporoP8_RS03800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SporoP8_RS03805	COG4708	membrane
SporoP8_RS03810	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS03820	COG2814	Major facilitator Superfamily
SporoP8_RS03840	COG3012	SEC-C Motif Domain Protein
SporoP8_RS03840	COG1405	negative regulation of cell septum assembly
SporoP8_RS03845	COG0535	radical SAM domain protein
SporoP8_RS03870	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS03875	COG5002	protein histidine kinase activity
SporoP8_RS03880	COG1999	signal sequence binding
SporoP8_RS03890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SporoP8_RS03905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SporoP8_RS03910	COG0140	phosphoribosyl-ATP diphosphatase activity
SporoP8_RS03910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SporoP8_RS03915	COG0107	imidazoleglycerol-phosphate synthase activity
SporoP8_RS03920	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SporoP8_RS03925	COG0131	Imidazoleglycerol-phosphate dehydratase
SporoP8_RS03930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SporoP8_RS03935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SporoP8_RS03940	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SporoP8_RS03945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SporoP8_RS03955	COG0137	argininosuccinate synthase activity
SporoP8_RS03960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SporoP8_RS03965	COG1388	LysM domain
SporoP8_RS03965	COG3858	chitin binding
SporoP8_RS03970	COG5577	PFAM Coat F domain
SporoP8_RS03980	COG2323	membrane
SporoP8_RS03990	COG2002	toxin-antitoxin pair type II binding
SporoP8_RS03995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS04000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SporoP8_RS04010	COG1011	Hydrolase
SporoP8_RS04020	COG0840	transmembrane signaling receptor activity
SporoP8_RS04025	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS04035	COG1335	isochorismatase
SporoP8_RS04040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SporoP8_RS04045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SporoP8_RS04050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SporoP8_RS04055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SporoP8_RS04055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SporoP8_RS04060	COG0307	riboflavin synthase, alpha
SporoP8_RS04065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SporoP8_RS04065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SporoP8_RS04070	COG4948	Mandelate Racemase Muconate Lactonizing
SporoP8_RS04080	COG1473	amidohydrolase
SporoP8_RS04085	COG0109	protoheme IX farnesyltransferase activity
SporoP8_RS04095	COG4176	ABC-type proline glycine betaine transport system permease component
SporoP8_RS04120	COG2322	membrane
SporoP8_RS04130	COG0697	spore germination
SporoP8_RS04135	COG0840	transmembrane signaling receptor activity
SporoP8_RS04160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SporoP8_RS04165	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SporoP8_RS04170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SporoP8_RS04180	COG1114	Component of the transport system for branched-chain amino acids
SporoP8_RS04190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SporoP8_RS04210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SporoP8_RS04220	COG1671	Belongs to the UPF0178 family
SporoP8_RS04230	COG3424	synthase
SporoP8_RS04235	COG1755	Isoprenylcysteine carboxyl methyltransferase
SporoP8_RS04240	COG1525	nuclease
SporoP8_RS04245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SporoP8_RS04250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SporoP8_RS04255	COG2267	carboxylic ester hydrolase activity
SporoP8_RS04260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SporoP8_RS04265	COG1840	ABC-type Fe3 transport system, periplasmic component
SporoP8_RS04270	COG3842	ATPase activity
SporoP8_RS04280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SporoP8_RS04295	COG1309	transcriptional regulator
SporoP8_RS04325	COG1506	peptidase
SporoP8_RS04330	COG0494	nUDIX hydrolase
SporoP8_RS04340	COG0281	malic enzyme
SporoP8_RS04350	COG0783	Belongs to the Dps family
SporoP8_RS04355	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SporoP8_RS04370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SporoP8_RS04375	COG0596	Alpha beta hydrolase
SporoP8_RS04385	COG1169	isochorismate synthase
SporoP8_RS04390	COG1575	Belongs to the MenA family. Type 1 subfamily
SporoP8_RS04395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SporoP8_RS04480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SporoP8_RS04530	COG1285	pathogenesis
SporoP8_RS04535	COG1979	alcohol dehydrogenase
SporoP8_RS04540	COG2155	Conserved Protein
SporoP8_RS04545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SporoP8_RS04550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SporoP8_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS04560	COG3829	transcription factor binding
SporoP8_RS04565	COG1098	S1 RNA binding domain
SporoP8_RS04580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SporoP8_RS04585	COG2814	Major facilitator Superfamily
SporoP8_RS04590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SporoP8_RS04600	COG2111	Na H antiporter
SporoP8_RS04600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SporoP8_RS04605	COG2111	Na H antiporter
SporoP8_RS04610	COG1006	Multisubunit Na H antiporter MnhC subunit
SporoP8_RS04615	COG0651	ATP synthesis coupled electron transport
SporoP8_RS04620	COG1863	multisubunit Na H antiporter MnhE subunit
SporoP8_RS04625	COG2212	antiporter activity
SporoP8_RS04630	COG1320	monovalent cation:proton antiporter activity
SporoP8_RS04640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SporoP8_RS04645	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
SporoP8_RS04655	COG1252	NADH dehydrogenase
SporoP8_RS04660	COG0316	Belongs to the HesB IscA family
SporoP8_RS04670	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SporoP8_RS04675	COG4837	Protein of unknown function (DUF1462)
SporoP8_RS04680	COG1252	NADH dehydrogenase
SporoP8_RS04685	COG4844	belongs to the
SporoP8_RS04690	COG0647	UMP catabolic process
SporoP8_RS04695	COG2445	Protein of unknown function DUF86
SporoP8_RS04700	COG4470	Protein conserved in bacteria
SporoP8_RS04705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SporoP8_RS04710	COG0733	neurotransmitter:sodium symporter activity
SporoP8_RS04715	COG1757	Na H antiporter
SporoP8_RS04725	COG0737	Belongs to the 5'-nucleotidase family
SporoP8_RS04730	COG0730	response to heat
SporoP8_RS04735	COG1801	Protein of unknown function DUF72
SporoP8_RS04745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS04760	COG2050	protein possibly involved in aromatic compounds catabolism
SporoP8_RS04765	COG0719	Fe-S assembly protein
SporoP8_RS04770	COG0822	iron-sulfur transferase activity
SporoP8_RS04775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SporoP8_RS04780	COG0719	Fe-S assembly protein
SporoP8_RS04785	COG0396	ATPase activity
SporoP8_RS04795	COG1464	Belongs to the NlpA lipoprotein family
SporoP8_RS04800	COG2011	ABC-type metal ion transport system permease component
SporoP8_RS04805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SporoP8_RS04810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS04815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SporoP8_RS04825	COG1393	Belongs to the ArsC family
SporoP8_RS04830	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS04835	COG0183	Belongs to the thiolase family
SporoP8_RS04840	COG1250	3-hydroxyacyl-CoA dehydrogenase
SporoP8_RS04840	COG1024	Enoyl-CoA hydratase
SporoP8_RS04845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS04860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SporoP8_RS04895	COG0277	FAD linked oxidase domain protein
SporoP8_RS04900	COG0385	Bile acid
SporoP8_RS04910	COG1999	signal sequence binding
SporoP8_RS04940	COG1595	DNA-templated transcription, initiation
SporoP8_RS04945	COG0726	polysaccharide deacetylase
SporoP8_RS04950	COG1999	signal sequence binding
SporoP8_RS04965	COG3773	Cell wall hydrolase
SporoP8_RS04970	COG0617	tRNA 3'-terminal CCA addition
SporoP8_RS04970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SporoP8_RS04970	COG3620	sequence-specific DNA binding
SporoP8_RS05025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SporoP8_RS05050	COG1063	alcohol dehydrogenase
SporoP8_RS05065	COG0471	metal ion transport
SporoP8_RS05070	COG4565	transcriptional regulatory protein
SporoP8_RS05075	COG3290	protein histidine kinase activity
SporoP8_RS05085	COG2031	fatty acid transporter
SporoP8_RS05090	COG1053	succinate dehydrogenase
SporoP8_RS05100	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS05110	COG1619	proteins homologs of microcin C7 resistance protein MccF
SporoP8_RS05120	COG0183	Belongs to the thiolase family
SporoP8_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS05130	COG1250	3-hydroxyacyl-CoA dehydrogenase
SporoP8_RS05135	COG2610	gluconate transmembrane transporter activity
SporoP8_RS05140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SporoP8_RS05160	COG1125	glycine betaine transport
SporoP8_RS05160	COG0517	IMP dehydrogenase activity
SporoP8_RS05165	COG1174	glycine betaine transport
SporoP8_RS05185	COG2911	Protein conserved in bacteria
SporoP8_RS05185	COG3266	domain, Protein
SporoP8_RS05185	COG1361	Conserved repeat domain
SporoP8_RS05195	COG1288	antiporter activity
SporoP8_RS05200	COG0726	polysaccharide deacetylase
SporoP8_RS05210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SporoP8_RS05230	COG2124	cytochrome p450
SporoP8_RS05235	COG4196	transglutaminase domain protein
SporoP8_RS05240	COG0477	Major facilitator Superfamily
SporoP8_RS05245	COG0318	PFAM AMP-dependent synthetase and ligase
SporoP8_RS05260	COG0786	glutamate:sodium symporter activity
SporoP8_RS05300	COG2911	Protein conserved in bacteria
SporoP8_RS05300	COG1361	Conserved repeat domain
SporoP8_RS05300	COG3266	domain, Protein
SporoP8_RS05340	COG0557	exoribonuclease II activity
SporoP8_RS05345	COG1647	Serine aminopeptidase, S33
SporoP8_RS05350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SporoP8_RS05360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SporoP8_RS05365	COG0149	triose-phosphate isomerase activity
SporoP8_RS05370	COG0126	phosphoglycerate kinase activity
SporoP8_RS05380	COG2390	Transcriptional regulator
SporoP8_RS05400	COG1704	LemA family
SporoP8_RS05405	COG1121	(ABC) transporter
SporoP8_RS05410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SporoP8_RS05415	COG0803	Belongs to the bacterial solute-binding protein 9 family
SporoP8_RS05420	COG0640	Transcriptional regulator
SporoP8_RS05425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SporoP8_RS05430	COG2323	membrane
SporoP8_RS05445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SporoP8_RS05455	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SporoP8_RS05465	COG1051	belongs to the nudix hydrolase family
SporoP8_RS05470	COG0492	ferredoxin-NADP+ reductase activity
SporoP8_RS05475	COG0457	Tetratricopeptide repeat
SporoP8_RS05480	COG0110	maltose O-acetyltransferase activity
SporoP8_RS05485	COG0546	phosphoglycolate phosphatase activity
SporoP8_RS05490	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SporoP8_RS05500	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SporoP8_RS05510	COG3595	metallopeptidase activity
SporoP8_RS05515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SporoP8_RS05520	COG0556	nucleotide-excision repair
SporoP8_RS05535	COG1131	(ABC) transporter
SporoP8_RS05540	COG0537	adenosine 5'-monophosphoramidase activity
SporoP8_RS05565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SporoP8_RS05570	COG3481	metal-dependent phosphohydrolase, HD sub domain
SporoP8_RS05575	COG4717	serine-type aminopeptidase activity
SporoP8_RS05580	COG0420	3'-5' exonuclease activity
SporoP8_RS05585	COG1668	transmembrane transport
SporoP8_RS05590	COG4152	abc transporter atp-binding protein
SporoP8_RS05600	COG1803	Methylglyoxal synthase
SporoP8_RS05605	COG1024	Enoyl-CoA hydratase
SporoP8_RS05610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SporoP8_RS05640	COG1253	flavin adenine dinucleotide binding
SporoP8_RS05645	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SporoP8_RS05655	COG0564	pseudouridine synthase activity
SporoP8_RS05660	COG0656	L-ascorbic acid biosynthetic process
SporoP8_RS05665	COG2252	PERMEase
SporoP8_RS05675	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SporoP8_RS05680	COG3382	B3 4 domain protein
SporoP8_RS05805	COG0735	belongs to the Fur family
SporoP8_RS05815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SporoP8_RS05825	COG4129	membrane
SporoP8_RS05830	COG1132	(ABC) transporter
SporoP8_RS05835	COG3557	Belongs to the UPF0374 family
SporoP8_RS05845	COG1194	a g-specific adenine glycosylase
SporoP8_RS05850	COG1988	membrane-bound metal-dependent
SporoP8_RS05860	COG2137	regulation of response to DNA damage stimulus
SporoP8_RS05865	COG1090	epimerase
SporoP8_RS05880	COG2217	Heavy metal translocating P-type atpase
SporoP8_RS05885	COG1295	ribonuclease BN
SporoP8_RS05895	COG1115	amino acid carrier protein
SporoP8_RS05900	COG4840	Belongs to the UPF0435 family
SporoP8_RS05905	COG1360	Flagellar Motor Protein
SporoP8_RS05910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SporoP8_RS05915	COG2309	aminopeptidase activity
SporoP8_RS05920	COG0288	reversible hydration of carbon dioxide
SporoP8_RS05925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SporoP8_RS05940	COG0024	Methionine aminopeptidase
SporoP8_RS05965	COG0564	pseudouridine synthase activity
SporoP8_RS05970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SporoP8_RS05980	COG0217	transcriptional regulatory protein
SporoP8_RS05995	COG0175	sulfate reduction
SporoP8_RS06005	COG0529	Catalyzes the synthesis of activated sulfate
SporoP8_RS06020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SporoP8_RS06020	COG1648	precorrin-2 dehydrogenase activity
SporoP8_RS06050	COG0683	leucine binding
SporoP8_RS06065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SporoP8_RS06070	COG0672	)-iron permease
SporoP8_RS06075	COG2837	iron assimilation
SporoP8_RS06095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SporoP8_RS06100	COG2124	cytochrome p450
SporoP8_RS06120	COG1982	Orn Lys Arg decarboxylase major
SporoP8_RS06125	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SporoP8_RS06130	COG0010	Belongs to the arginase family
SporoP8_RS06145	COG0387	Pfam Sodium calcium exchanger
SporoP8_RS06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SporoP8_RS06155	COG0601	transmembrane transport
SporoP8_RS06160	COG0747	negative chemotaxis
SporoP8_RS06165	COG4608	Belongs to the ABC transporter superfamily
SporoP8_RS06170	COG0444	Belongs to the ABC transporter superfamily
SporoP8_RS06185	COG0733	neurotransmitter:sodium symporter activity
SporoP8_RS06220	COG3377	Domain of unknown function (DUF1805)
SporoP8_RS06225	COG0174	glutamine synthetase
SporoP8_RS06230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SporoP8_RS06260	COG3403	YqcI/YcgG family
SporoP8_RS06265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SporoP8_RS06270	COG1902	pentaerythritol trinitrate reductase activity
SporoP8_RS06280	COG0693	protein deglycase activity
SporoP8_RS06285	COG2233	PERMEase
SporoP8_RS06300	COG1757	Na H antiporter
SporoP8_RS06310	COG0385	Bile acid
SporoP8_RS06315	COG0662	Cupin 2, conserved barrel domain protein
SporoP8_RS06325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SporoP8_RS06330	COG1294	oxidase, subunit
SporoP8_RS06335	COG1271	oxidase subunit
SporoP8_RS06345	COG1597	lipid kinase activity
SporoP8_RS06355	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SporoP8_RS06360	COG0154	amidase activity
SporoP8_RS06365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SporoP8_RS06370	COG4851	CamS sex pheromone cAM373 precursor
SporoP8_RS06380	COG0210	DNA helicase
SporoP8_RS06385	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
SporoP8_RS06390	COG4496	protein, YerC YecD
SporoP8_RS06395	COG1470	cell adhesion involved in biofilm formation
SporoP8_RS06400	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SporoP8_RS06405	COG0151	Belongs to the GarS family
SporoP8_RS06415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SporoP8_RS06425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SporoP8_RS06440	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SporoP8_RS06445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SporoP8_RS06450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SporoP8_RS06460	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SporoP8_RS06495	COG2252	PERMEase
SporoP8_RS06500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SporoP8_RS06500	COG0519	Catalyzes the synthesis of GMP from XMP
SporoP8_RS06505	COG1305	Transglutaminase-like
SporoP8_RS06510	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
SporoP8_RS06515	COG0714	Associated with various cellular activities
SporoP8_RS06525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SporoP8_RS06530	COG1556	Lactate utilization protein
SporoP8_RS06535	COG1139	Iron-sulfur cluster binding protein
SporoP8_RS06540	COG0247	lactate metabolic process
SporoP8_RS06545	COG2186	Transcriptional regulator
SporoP8_RS06550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SporoP8_RS06560	COG2076	Multidrug Resistance protein
SporoP8_RS06565	COG0626	cystathionine gamma-synthase activity
SporoP8_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS06580	COG0693	protein deglycase activity
SporoP8_RS06605	COG2329	Antibiotic biosynthesis monooxygenase
SporoP8_RS06625	COG0697	spore germination
SporoP8_RS06640	COG1607	acyl-coa hydrolase
SporoP8_RS06645	COG0561	phosphatase activity
SporoP8_RS06665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SporoP8_RS06675	COG0406	alpha-ribazole phosphatase activity
SporoP8_RS06680	COG2814	Major facilitator Superfamily
SporoP8_RS06685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SporoP8_RS06700	COG2318	DinB family
SporoP8_RS06705	COG2202	Pas domain
SporoP8_RS06705	COG1366	Belongs to the anti-sigma-factor antagonist family
SporoP8_RS06710	COG4608	Belongs to the ABC transporter superfamily
SporoP8_RS06715	COG0444	Belongs to the ABC transporter superfamily
SporoP8_RS06720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SporoP8_RS06725	COG0601	transmembrane transport
SporoP8_RS06730	COG4166	transmembrane transport
SporoP8_RS06760	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS06780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SporoP8_RS06800	COG0702	epimerase
SporoP8_RS06805	COG1309	transcriptional regulator
SporoP8_RS06810	COG0456	acetyltransferase
SporoP8_RS06825	COG0577	efflux transmembrane transporter activity
SporoP8_RS06830	COG1136	(ABC) transporter
SporoP8_RS06835	COG0642	Histidine kinase
SporoP8_RS06840	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS06850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SporoP8_RS06875	COG0589	response to stress
SporoP8_RS06880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SporoP8_RS06885	COG2132	Multicopper oxidase
SporoP8_RS06890	COG2176	DNA-directed DNA polymerase activity
SporoP8_RS06895	COG4721	ABC-type cobalt transport system, permease component
SporoP8_RS06900	COG1122	ATPase activity
SporoP8_RS06905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SporoP8_RS06915	COG1301	dicarboxylic acid transport
SporoP8_RS06925	COG1268	BioY protein
SporoP8_RS06930	COG1309	transcriptional regulator
SporoP8_RS06935	COG1301	dicarboxylic acid transport
SporoP8_RS06940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SporoP8_RS06945	COG0328	RNA-DNA hybrid ribonuclease activity
SporoP8_RS06950	COG3706	GGDEF domain
SporoP8_RS06960	COG0589	response to stress
SporoP8_RS06970	COG1760	l-serine dehydratase
SporoP8_RS06975	COG1464	Belongs to the NlpA lipoprotein family
SporoP8_RS06980	COG2011	ABC-type metal ion transport system permease component
SporoP8_RS06985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SporoP8_RS06990	COG0436	Aminotransferase
SporoP8_RS06995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SporoP8_RS07000	COG0778	Nitroreductase
SporoP8_RS07005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SporoP8_RS07020	COG5006	permease, DMT superfamily
SporoP8_RS07030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SporoP8_RS07040	COG0028	Belongs to the TPP enzyme family
SporoP8_RS07055	COG2056	Na+-H+ antiporter family
SporoP8_RS07060	COG2986	histidine ammonia-lyase
SporoP8_RS07065	COG1228	amidohydrolase
SporoP8_RS07070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SporoP8_RS07090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SporoP8_RS07095	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SporoP8_RS07100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SporoP8_RS07105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SporoP8_RS07150	COG1401	restriction endodeoxyribonuclease activity
SporoP8_RS07155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SporoP8_RS07175	COG1396	sequence-specific DNA binding
SporoP8_RS07180	COG0582	viral genome integration into host DNA
SporoP8_RS07195	COG1266	CAAX protease self-immunity
SporoP8_RS07200	COG2027	D-alanyl-D-alanine carboxypeptidase
SporoP8_RS07205	COG0805	protein transport
SporoP8_RS07210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SporoP8_RS07220	COG0488	(ABC) transporter
SporoP8_RS07225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SporoP8_RS07230	COG0456	acetyltransferase
SporoP8_RS07235	COG1214	PFAM Peptidase M22, glycoprotease
SporoP8_RS07240	COG0802	atpase or kinase
SporoP8_RS07290	COG3091	SprT-like family
SporoP8_RS07295	COG2183	response to ionizing radiation
SporoP8_RS07300	COG2208	phosphoserine phosphatase activity
SporoP8_RS07305	COG1191	sigma factor activity
SporoP8_RS07315	COG1366	Belongs to the anti-sigma-factor antagonist family
SporoP8_RS07320	COG2208	phosphoserine phosphatase activity
SporoP8_RS07325	COG2172	sigma factor antagonist activity
SporoP8_RS07330	COG1366	Belongs to the anti-sigma-factor antagonist family
SporoP8_RS07335	COG1366	Belongs to the anti-sigma-factor antagonist family
SporoP8_RS07340	COG2337	Toxic component of a toxin-antitoxin (TA) module
SporoP8_RS07350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SporoP8_RS07355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SporoP8_RS07360	COG0736	holo-[acyl-carrier-protein] synthase activity
SporoP8_RS07365	COG0705	Rhomboid family
SporoP8_RS07370	COG3428	Bacterial PH domain
SporoP8_RS07375	COG3402	PFAM membrane-flanked domain
SporoP8_RS07380	COG0513	Belongs to the DEAD box helicase family
SporoP8_RS07390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SporoP8_RS07395	COG1181	Belongs to the D-alanine--D-alanine ligase family
SporoP8_RS07400	COG0772	Belongs to the SEDS family
SporoP8_RS07405	COG2824	Alkylphosphonate utilization operon protein PhnA
SporoP8_RS07410	COG1937	Protein conserved in bacteria
SporoP8_RS07415	COG2608	mercury ion transmembrane transporter activity
SporoP8_RS07420	COG2217	Heavy metal translocating P-type atpase
SporoP8_RS07430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SporoP8_RS07435	COG1876	peptidase activity
SporoP8_RS07440	COG2814	Major facilitator Superfamily
SporoP8_RS07465	COG3153	acetyltransferase
SporoP8_RS07485	COG2996	Protein conserved in bacteria
SporoP8_RS07505	COG1320	monovalent cation:proton antiporter activity
SporoP8_RS07510	COG2212	antiporter activity
SporoP8_RS07515	COG1863	multisubunit Na H antiporter MnhE subunit
SporoP8_RS07520	COG0651	ATP synthesis coupled electron transport
SporoP8_RS07525	COG1006	Multisubunit Na H antiporter MnhC subunit
SporoP8_RS07530	COG2111	Na H antiporter
SporoP8_RS07535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SporoP8_RS07535	COG2111	Na H antiporter
SporoP8_RS07545	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SporoP8_RS07555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SporoP8_RS07560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SporoP8_RS07560	COG0723	plastoquinol--plastocyanin reductase activity
SporoP8_RS07565	COG1227	inorganic diphosphatase activity
SporoP8_RS07570	COG1959	2 iron, 2 sulfur cluster binding
SporoP8_RS07580	COG3949	Membrane
SporoP8_RS07585	COG2094	Belongs to the DNA glycosylase MPG family
SporoP8_RS07590	COG1132	(ABC) transporter
SporoP8_RS07600	COG0477	Major facilitator Superfamily
SporoP8_RS07605	COG4607	ABC-type enterochelin transport system periplasmic component
SporoP8_RS07610	COG4604	ABC transporter, ATP-binding protein
SporoP8_RS07615	COG4605	iron ion homeostasis
SporoP8_RS07620	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SporoP8_RS07630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SporoP8_RS07650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SporoP8_RS07660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SporoP8_RS07665	COG0393	Putative heavy-metal-binding
SporoP8_RS07670	COG4895	conserved protein (DUF2196)
SporoP8_RS07680	COG5002	protein histidine kinase activity
SporoP8_RS07690	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS07695	COG3706	GGDEF domain
SporoP8_RS07710	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SporoP8_RS07715	COG5662	AntiSigma factor
SporoP8_RS07720	COG1595	DNA-templated transcription, initiation
SporoP8_RS07725	COG0010	Belongs to the arginase family
SporoP8_RS07730	COG5001	Diguanylate cyclase
SporoP8_RS07730	COG3300	MHYT domain
SporoP8_RS07765	COG2194	sulfuric ester hydrolase activity
SporoP8_RS07775	COG0489	protein tyrosine kinase activity
SporoP8_RS07780	COG0860	N-Acetylmuramoyl-L-alanine amidase
SporoP8_RS07785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SporoP8_RS07795	COG2368	4-hydroxyphenylacetate
SporoP8_RS07800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
SporoP8_RS07810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SporoP8_RS07825	COG0829	nickel cation binding
SporoP8_RS07830	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SporoP8_RS07835	COG0830	nickel cation binding
SporoP8_RS07840	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SporoP8_RS07850	COG0832	Belongs to the urease beta subunit family
SporoP8_RS07855	COG0831	urea catabolic process
SporoP8_RS07865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SporoP8_RS07870	COG0101	tRNA pseudouridine synthase activity
SporoP8_RS07875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SporoP8_RS07880	COG1122	ATPase activity
SporoP8_RS07885	COG1122	ATPase activity
SporoP8_RS07895	COG0202	RNA polymerase activity
SporoP8_RS07900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SporoP8_RS07910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SporoP8_RS07915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SporoP8_RS07925	COG0201	protein transport
SporoP8_RS07930	COG0200	Binds to the 23S rRNA
SporoP8_RS07945	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SporoP8_RS07950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SporoP8_RS07965	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SporoP8_RS07970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SporoP8_RS07980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SporoP8_RS07985	COG0255	Belongs to the universal ribosomal protein uL29 family
SporoP8_RS07990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SporoP8_RS08010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SporoP8_RS08045	COG0049	tRNA binding
SporoP8_RS08065	COG2813	Specifically methylates the guanine in position
SporoP8_RS08070	COG0222	ribosome binding
SporoP8_RS08090	COG0250	Participates in transcription elongation, termination and antitermination
SporoP8_RS08095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SporoP8_RS08110	COG3688	RNA-binding protein containing a PIN domain
SporoP8_RS08115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SporoP8_RS08130	COG1045	serine acetyltransferase
SporoP8_RS08150	COG4956	integral membrane protein (PIN domain superfamily)
SporoP8_RS08155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SporoP8_RS08160	COG0542	response to heat
SporoP8_RS08165	COG3869	Catalyzes the specific phosphorylation of arginine residues in
SporoP8_RS08180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SporoP8_RS08185	COG1268	BioY protein
SporoP8_RS08195	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SporoP8_RS08195	COG0646	methionine synthase
SporoP8_RS08200	COG1410	methionine synthase
SporoP8_RS08200	COG0646	methionine synthase
SporoP8_RS08210	COG3011	Protein conserved in bacteria
SporoP8_RS08220	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS08250	COG0351	phosphomethylpyrimidine kinase
SporoP8_RS08255	COG0352	thiamine-phosphate diphosphorylase activity
SporoP8_RS08270	COG2197	response regulator
SporoP8_RS08275	COG4585	Histidine kinase
SporoP8_RS08280	COG3239	Fatty acid desaturase
SporoP8_RS08285	COG0671	phosphoesterase, PA-phosphatase related
SporoP8_RS08290	COG1970	mechanosensitive ion channel activity
SporoP8_RS08295	COG1607	acyl-coa hydrolase
SporoP8_RS08300	COG0791	NLP P60 protein
SporoP8_RS08305	COG4948	Mandelate Racemase Muconate Lactonizing
SporoP8_RS08310	COG1619	proteins homologs of microcin C7 resistance protein MccF
SporoP8_RS08330	COG0134	indole-3-glycerol-phosphate synthase activity
SporoP8_RS08335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SporoP8_RS08340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SporoP8_RS08345	COG1187	pseudouridine synthase activity
SporoP8_RS08355	COG2233	PERMEase
SporoP8_RS08370	COG0702	epimerase
SporoP8_RS08380	COG1119	ATPase activity
SporoP8_RS08390	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SporoP8_RS08405	COG3546	catalase activity
SporoP8_RS08415	COG0753	catalase activity
SporoP8_RS08430	COG0596	Alpha beta hydrolase
SporoP8_RS08440	COG2814	Major facilitator Superfamily
SporoP8_RS08460	COG3483	tryptophan 2,3-dioxygenase activity
SporoP8_RS08470	COG3844	kynureninase activity
SporoP8_RS08485	COG1126	abc transporter atp-binding protein
SporoP8_RS08490	COG0765	amino acid transport
SporoP8_RS08495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SporoP8_RS08505	COG1757	Na H antiporter
SporoP8_RS08515	COG2323	membrane
SporoP8_RS08520	COG0456	acetyltransferase
SporoP8_RS08535	COG1131	(ABC) transporter
SporoP8_RS08545	COG0516	GMP reductase activity
SporoP8_RS08580	COG0318	PFAM AMP-dependent synthetase and ligase
SporoP8_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS08595	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SporoP8_RS08595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SporoP8_RS08605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SporoP8_RS08620	COG3835	regulator
SporoP8_RS08630	COG0039	L-malate dehydrogenase activity
SporoP8_RS08635	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SporoP8_RS08640	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SporoP8_RS08645	COG4869	propanediol catabolic process
SporoP8_RS08655	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS08655	COG1454	alcohol dehydrogenase
SporoP8_RS08665	COG4302	ethanolamine ammonia-lyase activity
SporoP8_RS08670	COG4303	Ethanolamine ammonia lyase large subunit
SporoP8_RS08675	COG4819	ethanolamine utilization protein
SporoP8_RS08680	COG4917	ethanolamine utilization protein
SporoP8_RS08685	COG4810	utilization protein
SporoP8_RS08690	COG3192	ethanolamine utilization protein
SporoP8_RS08705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SporoP8_RS08715	COG4608	Belongs to the ABC transporter superfamily
SporoP8_RS08720	COG0444	Belongs to the ABC transporter superfamily
SporoP8_RS08730	COG0601	transmembrane transport
SporoP8_RS08735	COG0747	negative chemotaxis
SporoP8_RS08765	COG1361	Conserved repeat domain
SporoP8_RS08785	COG0733	neurotransmitter:sodium symporter activity
SporoP8_RS08790	COG1956	GAF domain-containing protein
SporoP8_RS08800	COG0477	Major facilitator Superfamily
SporoP8_RS08810	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SporoP8_RS08815	COG0709	Synthesizes selenophosphate from selenide and ATP
SporoP8_RS08835	COG1757	Na H antiporter
SporoP8_RS08840	COG1063	alcohol dehydrogenase
SporoP8_RS08845	COG1834	amidinotransferase
SporoP8_RS08850	COG0477	Major facilitator Superfamily
SporoP8_RS08855	COG1846	Transcriptional regulator
SporoP8_RS08865	COG2258	MOSC domain
SporoP8_RS08870	COG0492	ferredoxin-NADP+ reductase activity
SporoP8_RS08875	COG1120	ATPase activity
SporoP8_RS08880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SporoP8_RS08885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SporoP8_RS08890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SporoP8_RS08895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SporoP8_RS08905	COG2188	Transcriptional regulator
SporoP8_RS08910	COG1250	3-hydroxyacyl-CoA dehydrogenase
SporoP8_RS08915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SporoP8_RS08920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SporoP8_RS08925	COG0583	DNA-binding transcription factor activity
SporoP8_RS08930	COG0488	(ABC) transporter
SporoP8_RS08935	COG0747	negative chemotaxis
SporoP8_RS08940	COG1473	amidohydrolase
SporoP8_RS08955	COG1595	DNA-templated transcription, initiation
SporoP8_RS08980	COG2155	Conserved Protein
SporoP8_RS08985	COG1752	Esterase of the alpha-beta hydrolase superfamily
SporoP8_RS08995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SporoP8_RS09000	COG1725	Transcriptional regulator
SporoP8_RS09015	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SporoP8_RS09020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SporoP8_RS09025	COG2132	Multicopper oxidase
SporoP8_RS09035	COG0494	nUDIX hydrolase
SporoP8_RS09060	COG1562	ergosterol biosynthetic process
SporoP8_RS09080	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS09085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SporoP8_RS09090	COG1757	Na H antiporter
SporoP8_RS09100	COG3938	Belongs to the proline racemase family
SporoP8_RS09105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SporoP8_RS09110	COG3829	transcription factor binding
SporoP8_RS09110	COG3290	protein histidine kinase activity
SporoP8_RS09130	COG0579	oxidoreductase
SporoP8_RS09140	COG1764	response to oxidative stress
SporoP8_RS09150	COG0494	nUDIX hydrolase
SporoP8_RS09155	COG4509	Sortase family
SporoP8_RS09160	COG1120	ATPase activity
SporoP8_RS09185	COG5386	Cell surface protein
SporoP8_RS09195	COG0084	hydrolase, TatD family'
SporoP8_RS09200	COG3739	integral membrane protein
SporoP8_RS09205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SporoP8_RS09210	COG4807	Protein conserved in bacteria
SporoP8_RS09215	COG1733	regulation of RNA biosynthetic process
SporoP8_RS09225	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SporoP8_RS09235	COG2918	glutathione biosynthetic process
SporoP8_RS09235	COG1181	Belongs to the D-alanine--D-alanine ligase family
SporoP8_RS09240	COG0300	oxidoreductase activity
SporoP8_RS09245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SporoP8_RS09250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SporoP8_RS09255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SporoP8_RS09260	COG4853	Protein conserved in bacteria
SporoP8_RS09265	COG4863	YycH protein
SporoP8_RS09270	COG5002	protein histidine kinase activity
SporoP8_RS09275	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS09280	COG0305	Participates in initiation and elongation during chromosome replication
SporoP8_RS09285	COG0359	binds to the 23S rRNA
SporoP8_RS09290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SporoP8_RS09300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SporoP8_RS09320	COG0012	GTP binding
SporoP8_RS09325	COG4481	Protein conserved in bacteria
SporoP8_RS09330	COG0668	transmembrane transport
SporoP8_RS09340	COG1811	Na channel or pump
SporoP8_RS09345	COG1475	DNA binding
SporoP8_RS09350	COG1192	Involved in chromosome partitioning
SporoP8_RS09375	COG1847	R3H domain protein
SporoP8_RS09380	COG0706	membrane insertase activity
SporoP8_RS09385	COG0594	ribonuclease P activity
SporoP8_RS09390	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SporoP8_RS09400	COG0592	DNA-directed DNA polymerase activity
SporoP8_RS09405	COG2501	S4 domain
SporoP8_RS09415	COG0187	DNA topoisomerase II activity
SporoP8_RS09420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SporoP8_RS09445	COG0386	Belongs to the glutathione peroxidase family
SporoP8_RS09450	COG0516	GMP reductase activity
SporoP8_RS09450	COG0517	IMP dehydrogenase activity
SporoP8_RS09460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SporoP8_RS09465	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SporoP8_RS09470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SporoP8_RS09475	COG0590	tRNA wobble adenosine to inosine editing
SporoP8_RS09480	COG1428	Deoxynucleoside kinase
SporoP8_RS09485	COG1428	Deoxynucleoside kinase
SporoP8_RS09490	COG0527	aspartate kinase activity
SporoP8_RS09495	COG0460	homoserine dehydrogenase
SporoP8_RS09500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SporoP8_RS09505	COG0083	homoserine kinase activity
SporoP8_RS09520	COG1854	S-ribosylhomocysteine lyase activity
SporoP8_RS09525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SporoP8_RS09530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SporoP8_RS09535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SporoP8_RS09565	COG1396	sequence-specific DNA binding
SporoP8_RS09580	COG2909	trisaccharide binding
SporoP8_RS09585	COG1982	Orn Lys Arg decarboxylase major
SporoP8_RS09590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SporoP8_RS09595	COG3870	Protein conserved in bacteria
SporoP8_RS09600	COG1728	Protein conserved in bacteria
SporoP8_RS09605	COG0470	DNA polymerase III
SporoP8_RS09610	COG1774	PSP1 C-terminal conserved region
SporoP8_RS09615	COG4467	Involved in initiation control of chromosome replication
SporoP8_RS09620	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SporoP8_RS09630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SporoP8_RS09635	COG2002	toxin-antitoxin pair type II binding
SporoP8_RS09645	COG0084	hydrolase, TatD family'
SporoP8_RS09650	COG3584	3D domain protein
SporoP8_RS09650	COG3583	domain protein
SporoP8_RS09665	COG4466	Protein conserved in bacteria
SporoP8_RS09675	COG3266	domain, Protein
SporoP8_RS09675	COG1361	Conserved repeat domain
SporoP8_RS09675	COG2911	Protein conserved in bacteria
SporoP8_RS09685	COG2070	2-Nitropropane dioxygenase
SporoP8_RS09700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SporoP8_RS09705	COG0251	oxidation-reduction process
SporoP8_RS09710	COG2088	sporulation resulting in formation of a cellular spore
SporoP8_RS09715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SporoP8_RS09720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SporoP8_RS09725	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SporoP8_RS09730	COG0193	aminoacyl-tRNA hydrolase activity
SporoP8_RS09740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SporoP8_RS09745	COG2002	toxin-antitoxin pair type II binding
SporoP8_RS09750	COG0281	malic enzyme
SporoP8_RS09760	COG2244	polysaccharide biosynthetic process
SporoP8_RS09765	COG3956	TIGRFAM MazG family protein
SporoP8_RS09770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SporoP8_RS09790	COG1098	S1 RNA binding domain
SporoP8_RS09800	COG2208	phosphoserine phosphatase activity
SporoP8_RS09805	COG0037	tRNA processing
SporoP8_RS09810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SporoP8_RS09815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SporoP8_RS09820	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SporoP8_RS09825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SporoP8_RS09830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SporoP8_RS09835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS09840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SporoP8_RS09845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SporoP8_RS09850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SporoP8_RS09855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SporoP8_RS09860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SporoP8_RS09900	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SporoP8_RS09945	COG1295	ribonuclease BN
SporoP8_RS09950	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS09955	COG3850	Histidine kinase
SporoP8_RS09955	COG5002	protein histidine kinase activity
SporoP8_RS09980	COG5001	Diguanylate cyclase
SporoP8_RS09990	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS09990	COG2972	Histidine kinase
SporoP8_RS10000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SporoP8_RS10005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SporoP8_RS10020	COG1115	amino acid carrier protein
SporoP8_RS10030	COG3829	transcription factor binding
SporoP8_RS10035	COG0492	ferredoxin-NADP+ reductase activity
SporoP8_RS10040	COG1141	Ferredoxin
SporoP8_RS10045	COG4638	Rieske (2fe-2S)
SporoP8_RS10050	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS10055	COG0473	3-isopropylmalate dehydrogenase activity
SporoP8_RS10060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SporoP8_RS10065	COG0425	Belongs to the sulfur carrier protein TusA family
SporoP8_RS10070	COG2391	methyltransferase activity
SporoP8_RS10075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SporoP8_RS10080	COG0778	Nitroreductase
SporoP8_RS10085	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SporoP8_RS10090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SporoP8_RS10100	COG0697	spore germination
SporoP8_RS10105	COG2188	Transcriptional regulator
SporoP8_RS10120	COG3626	phosphonate metabolism
SporoP8_RS10125	COG3627	carbon phosphorus lyase activity
SporoP8_RS10130	COG4107	phosphonate C-P lyase system protein PhnK
SporoP8_RS10135	COG3454	Phosphonate metabolism
SporoP8_RS10140	COG4778	phosphonate C-P lyase system protein PhnL
SporoP8_RS10145	COG0613	PHP domain protein
SporoP8_RS10155	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SporoP8_RS10165	COG3639	organic phosphonate transmembrane transporter activity
SporoP8_RS10170	COG0702	epimerase
SporoP8_RS10175	COG4191	Histidine kinase
SporoP8_RS10180	COG0784	Response regulator, receiver
SporoP8_RS10190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SporoP8_RS10215	COG1174	glycine betaine transport
SporoP8_RS10220	COG1125	glycine betaine transport
SporoP8_RS10220	COG0517	IMP dehydrogenase activity
SporoP8_RS10230	COG1136	(ABC) transporter
SporoP8_RS10235	COG3258	Cytochrome c
SporoP8_RS10285	COG2814	Major facilitator Superfamily
SporoP8_RS10290	COG0471	metal ion transport
SporoP8_RS10295	COG0628	permease
SporoP8_RS10310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SporoP8_RS10330	COG0697	spore germination
SporoP8_RS10335	COG2195	Cleaves the N-terminal amino acid of tripeptides
SporoP8_RS10340	COG0786	glutamate:sodium symporter activity
SporoP8_RS10350	COG0583	DNA-binding transcription factor activity
SporoP8_RS10360	COG0583	DNA-binding transcription factor activity
SporoP8_RS10370	COG1937	Protein conserved in bacteria
SporoP8_RS10375	COG2210	Belongs to the sulfur carrier protein TusA family
SporoP8_RS10380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SporoP8_RS10380	COG0425	Belongs to the sulfur carrier protein TusA family
SporoP8_RS10385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SporoP8_RS10385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SporoP8_RS10390	COG0425	Belongs to the sulfur carrier protein TusA family
SporoP8_RS10395	COG0730	response to heat
SporoP8_RS10400	COG2873	o-acetylhomoserine
SporoP8_RS10405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SporoP8_RS10415	COG3693	PFAM glycoside hydrolase, family 10
SporoP8_RS10450	COG5002	protein histidine kinase activity
SporoP8_RS10490	COG4585	Histidine kinase
SporoP8_RS10495	COG2197	response regulator
SporoP8_RS10500	COG1968	undecaprenyl-diphosphatase activity
SporoP8_RS10505	COG1234	tRNA 3'-trailer cleavage
SporoP8_RS10510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SporoP8_RS10530	COG0415	Belongs to the DNA photolyase family
SporoP8_RS10545	COG0840	transmembrane signaling receptor activity
SporoP8_RS10550	COG0577	efflux transmembrane transporter activity
SporoP8_RS10555	COG1136	(ABC) transporter
SporoP8_RS10560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SporoP8_RS10565	COG2022	thiamine diphosphate biosynthetic process
SporoP8_RS10570	COG2104	thiamine diphosphate biosynthetic process
SporoP8_RS10575	COG0352	thiamine-phosphate diphosphorylase activity
SporoP8_RS10585	COG2032	superoxide dismutase activity
SporoP8_RS10600	COG2340	Cysteine-rich secretory protein family
SporoP8_RS10610	COG2409	Drug exporters of the RND superfamily
SporoP8_RS10615	COG1278	Cold shock
SporoP8_RS10620	COG0306	phosphate transporter
SporoP8_RS10625	COG1392	Phosphate transport regulator
SporoP8_RS10655	COG2153	protein acetylation
SporoP8_RS10660	COG2353	YceI-like domain
SporoP8_RS10670	COG0346	lactoylglutathione lyase activity
SporoP8_RS10675	COG1846	Transcriptional regulator
SporoP8_RS10690	COG1595	DNA-templated transcription, initiation
SporoP8_RS10740	COG1361	Conserved repeat domain
SporoP8_RS10745	COG1131	(ABC) transporter
SporoP8_RS10750	COG3559	Exporter of polyketide antibiotics
SporoP8_RS10765	COG1361	Conserved repeat domain
SporoP8_RS10780	COG0010	Belongs to the arginase family
SporoP8_RS10790	COG0805	protein transport
SporoP8_RS10795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SporoP8_RS10800	COG1361	Conserved repeat domain
SporoP8_RS10800	COG2911	Protein conserved in bacteria
SporoP8_RS10800	COG3266	domain, Protein
SporoP8_RS10835	COG0318	PFAM AMP-dependent synthetase and ligase
SporoP8_RS10840	COG0183	Belongs to the thiolase family
SporoP8_RS10845	COG3829	transcription factor binding
SporoP8_RS10850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SporoP8_RS10860	COG0697	spore germination
SporoP8_RS10865	COG3177	Filamentation induced by cAMP protein fic
SporoP8_RS10870	COG1785	Belongs to the alkaline phosphatase family
SporoP8_RS10875	COG2508	Transcriptional regulator
SporoP8_RS10900	COG4126	flavin adenine dinucleotide binding
SporoP8_RS10905	COG0697	spore germination
SporoP8_RS10920	COG0305	Participates in initiation and elongation during chromosome replication
SporoP8_RS10940	COG2378	regulation of single-species biofilm formation
SporoP8_RS10945	COG4191	Histidine kinase
SporoP8_RS10960	COG0598	Magnesium transport protein CorA
SporoP8_RS10980	COG5658	integral membrane protein
SporoP8_RS10985	COG0640	Transcriptional regulator
SporoP8_RS11040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SporoP8_RS11040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SporoP8_RS11050	COG1061	Type III restriction enzyme res subunit
SporoP8_RS11060	COG2199	diguanylate cyclase activity
SporoP8_RS11060	COG2200	EAL domain
SporoP8_RS11060	COG2202	Pas domain
SporoP8_RS11065	COG0784	Response regulator, receiver
SporoP8_RS11065	COG0835	chemotaxis
SporoP8_RS11070	COG0346	lactoylglutathione lyase activity
SporoP8_RS11205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SporoP8_RS11235	COG0277	FAD linked oxidase domain protein
SporoP8_RS11255	COG1823	symporter activity
SporoP8_RS11285	COG0586	Pfam SNARE associated Golgi protein
SporoP8_RS11290	COG2112	serine threonine protein kinase
SporoP8_RS11295	COG1307	EDD domain protein, DegV family
SporoP8_RS11305	COG0789	Transcriptional regulator
SporoP8_RS11310	COG2318	DinB family
SporoP8_RS11315	COG1742	UPF0060 membrane protein
SporoP8_RS11340	COG1929	Belongs to the glycerate kinase type-1 family
SporoP8_RS11345	COG1115	amino acid carrier protein
SporoP8_RS11350	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SporoP8_RS11355	COG0716	FMN binding
SporoP8_RS11360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SporoP8_RS11365	COG0427	acetyl-CoA hydrolase
SporoP8_RS11370	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SporoP8_RS11375	COG1140	nitrate reductase beta subunit
SporoP8_RS11385	COG2181	nitrate reductase activity
SporoP8_RS11395	COG4585	Histidine kinase
SporoP8_RS11400	COG2197	response regulator
SporoP8_RS11410	COG2223	nitrite transmembrane transporter activity
SporoP8_RS11415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SporoP8_RS11420	COG0521	Mo-molybdopterin cofactor biosynthetic process
SporoP8_RS11425	COG0315	cyclic pyranopterin monophosphate synthase activity
SporoP8_RS11430	COG0303	'Molybdopterin
SporoP8_RS11440	COG0314	molybdopterin synthase activity
SporoP8_RS11450	COG0746	molybdenum cofactor guanylyltransferase activity
SporoP8_RS11455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SporoP8_RS11460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SporoP8_RS11470	COG2814	Major facilitator Superfamily
SporoP8_RS11480	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS11495	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS11500	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS11505	COG0436	Aminotransferase
SporoP8_RS11520	COG3300	MHYT domain
SporoP8_RS11520	COG5001	Diguanylate cyclase
SporoP8_RS11525	COG0697	spore germination
SporoP8_RS11530	COG1132	(ABC) transporter
SporoP8_RS11535	COG1132	(ABC) transporter
SporoP8_RS11575	COG0765	amino acid transport
SporoP8_RS11580	COG1126	abc transporter atp-binding protein
SporoP8_RS11590	COG0778	Nitroreductase
SporoP8_RS11600	COG4535	Mg2 and Co2 transporter CorC
SporoP8_RS11630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SporoP8_RS11635	COG2364	Membrane
SporoP8_RS11645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SporoP8_RS11650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SporoP8_RS11665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SporoP8_RS11680	COG2363	Small membrane protein
SporoP8_RS11690	COG3253	May function as heme-dependent peroxidase
SporoP8_RS11695	COG0280	phosphate acetyltransferase
SporoP8_RS11710	COG1078	dGTPase activity
SporoP8_RS11715	COG3465	dGTPase activity
SporoP8_RS11735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SporoP8_RS11745	COG0018	arginyl-trna synthetase
SporoP8_RS11755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SporoP8_RS11760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SporoP8_RS11765	COG1120	ATPase activity
SporoP8_RS11770	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SporoP8_RS11785	COG1492	cobalamin metabolic process
SporoP8_RS11790	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SporoP8_RS11805	COG2096	Adenosyltransferase
SporoP8_RS11810	COG1454	alcohol dehydrogenase
SporoP8_RS11820	COG0183	Belongs to the thiolase family
SporoP8_RS11825	COG1250	3-hydroxyacyl-CoA dehydrogenase
SporoP8_RS11830	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS11835	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS11840	COG3226	Transcriptional regulator
SporoP8_RS11845	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SporoP8_RS11845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SporoP8_RS11845	COG1703	isobutyryl-CoA mutase activity
SporoP8_RS11855	COG0504	CTP synthase activity
SporoP8_RS11865	COG2204	response regulator
SporoP8_RS11870	COG0191	fructose-bisphosphate aldolase activity
SporoP8_RS11880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SporoP8_RS11885	COG1494	fructose-1,6-bisphosphatase
SporoP8_RS11890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SporoP8_RS11900	COG1435	thymidine kinase activity
SporoP8_RS11905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SporoP8_RS11910	COG2890	protein-(glutamine-N5) methyltransferase activity
SporoP8_RS11920	COG0009	L-threonylcarbamoyladenylate synthase
SporoP8_RS11935	COG0840	transmembrane signaling receptor activity
SporoP8_RS11940	COG0698	ribose 5-phosphate isomerase
SporoP8_RS11945	COG4475	Protein of unknown function (DUF436)
SporoP8_RS11960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SporoP8_RS11965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SporoP8_RS11975	COG0356	it plays a direct role in the translocation of protons across the membrane
SporoP8_RS11980	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SporoP8_RS12000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SporoP8_RS12025	COG2385	sporulation resulting in formation of a cellular spore
SporoP8_RS12035	COG1609	Transcriptional regulator
SporoP8_RS12050	COG4786	Flagellar basal body rod
SporoP8_RS12055	COG4786	Flagellar basal body rod
SporoP8_RS12085	COG0629	single-stranded DNA binding
SporoP8_RS12095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SporoP8_RS12140	COG3409	Peptidoglycan-binding domain 1 protein
SporoP8_RS12140	COG0793	Belongs to the peptidase S41A family
SporoP8_RS12155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SporoP8_RS12175	COG1361	Conserved repeat domain
SporoP8_RS12175	COG3266	domain, Protein
SporoP8_RS12175	COG2911	Protein conserved in bacteria
SporoP8_RS12195	COG1361	Conserved repeat domain
SporoP8_RS12200	COG1361	Conserved repeat domain
SporoP8_RS12200	COG2911	Protein conserved in bacteria
SporoP8_RS12200	COG3266	domain, Protein
SporoP8_RS12215	COG3944	biosynthesis protein
SporoP8_RS12220	COG0489	protein tyrosine kinase activity
SporoP8_RS12235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SporoP8_RS12240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SporoP8_RS12245	COG0110	maltose O-acetyltransferase activity
SporoP8_RS12260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SporoP8_RS12270	COG0110	maltose O-acetyltransferase activity
SporoP8_RS12280	COG0728	peptidoglycan biosynthetic process
SporoP8_RS12285	COG1063	alcohol dehydrogenase
SporoP8_RS12310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SporoP8_RS12315	COG1737	Transcriptional regulator
SporoP8_RS12320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SporoP8_RS12330	COG0765	amino acid transport
SporoP8_RS12335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SporoP8_RS12360	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS12375	COG2030	dehydratase
SporoP8_RS12375	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS12380	COG1960	acyl-CoA dehydrogenase activity
SporoP8_RS12385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SporoP8_RS12390	COG1042	CoA-binding domain protein
SporoP8_RS12390	COG0045	succinate-CoA ligase (ADP-forming) activity
SporoP8_RS12390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SporoP8_RS12395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SporoP8_RS12415	COG3835	regulator
SporoP8_RS12420	COG3119	arylsulfatase activity
SporoP8_RS12435	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SporoP8_RS12440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SporoP8_RS12445	COG2146	nitrite reductase [NAD(P)H] activity
SporoP8_RS12470	COG0596	Alpha beta hydrolase
SporoP8_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS12495	COG1349	DNA-binding transcription factor activity
SporoP8_RS12500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SporoP8_RS12510	COG0531	amino acid
SporoP8_RS12525	COG1454	alcohol dehydrogenase
SporoP8_RS12525	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS12535	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SporoP8_RS12565	COG0039	L-malate dehydrogenase activity
SporoP8_RS12575	COG1316	TRANSCRIPTIONal
SporoP8_RS12600	COG3944	biosynthesis protein
SporoP8_RS12605	COG0489	protein tyrosine kinase activity
SporoP8_RS12620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SporoP8_RS12625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SporoP8_RS12690	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS12720	COG2610	gluconate transmembrane transporter activity
SporoP8_RS12730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SporoP8_RS12750	COG1404	Belongs to the peptidase S8 family
SporoP8_RS12755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SporoP8_RS12760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SporoP8_RS12765	COG1116	anion transmembrane transporter activity
SporoP8_RS12775	COG1309	transcriptional regulator
SporoP8_RS12790	COG1609	Transcriptional regulator
SporoP8_RS12795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SporoP8_RS12800	COG1869	D-ribose catabolic process
SporoP8_RS12805	COG1129	ABC transporter
SporoP8_RS12810	COG1172	Belongs to the binding-protein-dependent transport system permease family
SporoP8_RS12815	COG1879	ABC-type sugar transport system periplasmic component
SporoP8_RS12835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SporoP8_RS12845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SporoP8_RS12860	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS12865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SporoP8_RS12870	COG0686	Belongs to the AlaDH PNT family
SporoP8_RS12875	COG4193	domain, Protein
SporoP8_RS12875	COG5263	repeat protein
SporoP8_RS12880	COG0492	ferredoxin-NADP+ reductase activity
SporoP8_RS12900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SporoP8_RS12910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SporoP8_RS12915	COG0390	transport system, permease component
SporoP8_RS12920	COG4607	ABC-type enterochelin transport system periplasmic component
SporoP8_RS12925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SporoP8_RS12950	COG3314	Sporulation integral membrane protein YlbJ
SporoP8_RS12955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SporoP8_RS12965	COG4187	Peptidase family M20/M25/M40
SporoP8_RS12980	COG0488	(ABC) transporter
SporoP8_RS12985	COG1413	lyase activity
SporoP8_RS12990	COG0840	transmembrane signaling receptor activity
SporoP8_RS12995	COG0840	transmembrane signaling receptor activity
SporoP8_RS13000	COG0583	DNA-binding transcription factor activity
SporoP8_RS13015	COG1033	growth of symbiont in host cell
SporoP8_RS13015	COG2409	Drug exporters of the RND superfamily
SporoP8_RS13020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SporoP8_RS13025	COG2851	Citrate transporter
SporoP8_RS13030	COG4565	transcriptional regulatory protein
SporoP8_RS13035	COG3290	protein histidine kinase activity
SporoP8_RS13040	COG1597	lipid kinase activity
SporoP8_RS13060	COG0154	amidase activity
SporoP8_RS13065	COG2239	Acts as a magnesium transporter
SporoP8_RS13070	COG3584	3D domain protein
SporoP8_RS13070	COG3583	domain protein
SporoP8_RS13075	COG3706	GGDEF domain
SporoP8_RS13095	COG0069	glutamate synthase activity
SporoP8_RS13100	COG1388	LysM domain
SporoP8_RS13100	COG0791	NLP P60 protein
SporoP8_RS13115	COG1309	transcriptional regulator
SporoP8_RS13120	COG2076	Multidrug Resistance protein
SporoP8_RS13135	COG0129	dihydroxy-acid dehydratase activity
SporoP8_RS13140	COG0028	Belongs to the TPP enzyme family
SporoP8_RS13145	COG0440	acetolactate synthase activity
SporoP8_RS13160	COG0473	3-isopropylmalate dehydrogenase activity
SporoP8_RS13170	COG0066	3-isopropylmalate dehydratase activity
SporoP8_RS13180	COG4193	domain, Protein
SporoP8_RS13180	COG5263	repeat protein
SporoP8_RS13205	COG2224	Isocitrate lyase
SporoP8_RS13210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SporoP8_RS13220	COG2247	cell wall binding repeat
SporoP8_RS13220	COG0860	N-Acetylmuramoyl-L-alanine amidase
SporoP8_RS13225	COG0791	NLP P60 protein
SporoP8_RS13230	COG0297	glycogen (starch) synthase activity
SporoP8_RS13230	COG0438	transferase activity, transferring glycosyl groups
SporoP8_RS13235	COG0728	peptidoglycan biosynthetic process
SporoP8_RS13240	COG0659	secondary active sulfate transmembrane transporter activity
SporoP8_RS13250	COG1388	LysM domain
SporoP8_RS13250	COG0791	NLP P60 protein
SporoP8_RS13255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SporoP8_RS13260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SporoP8_RS13270	COG0363	glucosamine-6-phosphate deaminase activity
SporoP8_RS13280	COG0791	NLP P60 protein
SporoP8_RS13290	COG0653	protein targeting
SporoP8_RS13295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SporoP8_RS13315	COG1316	TRANSCRIPTIONal
SporoP8_RS13320	COG1739	Uncharacterized protein family UPF0029
SporoP8_RS13325	COG4585	Histidine kinase
SporoP8_RS13330	COG2197	response regulator
SporoP8_RS13360	COG1473	amidohydrolase
SporoP8_RS13365	COG2329	Antibiotic biosynthesis monooxygenase
SporoP8_RS13370	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SporoP8_RS13375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SporoP8_RS13380	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SporoP8_RS13390	COG0095	Lipoate-protein ligase
SporoP8_RS13395	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS13400	COG5002	protein histidine kinase activity
SporoP8_RS13405	COG1136	(ABC) transporter
SporoP8_RS13410	COG0577	efflux transmembrane transporter activity
SporoP8_RS13420	COG0318	PFAM AMP-dependent synthetase and ligase
SporoP8_RS13425	COG4946	Tricorn protease homolog
SporoP8_RS13425	COG1506	peptidase
SporoP8_RS13425	COG0823	Involved in the tonB-independent uptake of proteins
SporoP8_RS13430	COG1027	Aspartate ammonia-lyase
SporoP8_RS13445	COG1307	EDD domain protein, DegV family
SporoP8_RS13450	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SporoP8_RS13465	COG2747	anti-sigma28 factor FlgM
SporoP8_RS13475	COG4786	Flagellar basal body rod
SporoP8_RS13475	COG1256	bacterial-type flagellum assembly
SporoP8_RS13480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SporoP8_RS13490	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
SporoP8_RS13495	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SporoP8_RS13505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SporoP8_RS13555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SporoP8_RS13560	COG1011	Hydrolase
SporoP8_RS13570	COG1414	Transcriptional regulator
SporoP8_RS13575	COG1984	allophanate hydrolase subunit 2
SporoP8_RS13580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SporoP8_RS13585	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SporoP8_RS13590	COG1914	H( )-stimulated, divalent metal cation uptake system
SporoP8_RS13595	COG4336	lyase activity
SporoP8_RS13600	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS13605	COG2610	gluconate transmembrane transporter activity
SporoP8_RS13610	COG3829	transcription factor binding
SporoP8_RS13625	COG0840	transmembrane signaling receptor activity
SporoP8_RS13640	COG0840	transmembrane signaling receptor activity
SporoP8_RS13645	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SporoP8_RS13650	COG1516	flagellar protein fliS
SporoP8_RS13685	COG0653	protein targeting
SporoP8_RS13690	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SporoP8_RS13700	COG2884	Cell division ATP-binding protein ftsE
SporoP8_RS13705	COG2177	Part of the ABC transporter FtsEX involved in
SporoP8_RS13710	COG4942	peptidase
SporoP8_RS13720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS13725	COG3409	Peptidoglycan-binding domain 1 protein
SporoP8_RS13725	COG0793	Belongs to the peptidase S41A family
SporoP8_RS13730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SporoP8_RS13745	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SporoP8_RS13750	COG0398	Pfam SNARE associated Golgi protein
SporoP8_RS13765	COG2311	Membrane
SporoP8_RS13785	COG1307	EDD domain protein, DegV family
SporoP8_RS13790	COG0561	phosphatase activity
SporoP8_RS13795	COG1073	alpha beta
SporoP8_RS13800	COG2151	metal-sulfur cluster biosynthetic enzyme
SporoP8_RS13820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SporoP8_RS13825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SporoP8_RS13840	COG1393	Belongs to the ArsC family
SporoP8_RS13845	COG4862	establishment of competence for transformation
SporoP8_RS13860	COG1164	Oligoendopeptidase f
SporoP8_RS13865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SporoP8_RS13870	COG2346	COG2346, Truncated hemoglobins
SporoP8_RS13875	COG0741	lytic transglycosylase activity
SporoP8_RS13890	COG0564	pseudouridine synthase activity
SporoP8_RS13895	COG2239	Acts as a magnesium transporter
SporoP8_RS13920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SporoP8_RS13950	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SporoP8_RS13955	COG2382	esterase
SporoP8_RS13960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SporoP8_RS13965	COG2358	TRAP transporter, solute receptor (TAXI family
SporoP8_RS14025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SporoP8_RS14030	COG0564	pseudouridine synthase activity
SporoP8_RS14040	COG1012	belongs to the aldehyde dehydrogenase family
SporoP8_RS14045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SporoP8_RS14050	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SporoP8_RS14060	COG0861	Integral membrane protein TerC family
SporoP8_RS14065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SporoP8_RS14075	COG5002	protein histidine kinase activity
SporoP8_RS14085	COG4873	Protein conserved in bacteria
SporoP8_RS14095	COG2084	Dehydrogenase
SporoP8_RS14105	COG0517	IMP dehydrogenase activity
SporoP8_RS14110	COG2814	Major facilitator Superfamily
SporoP8_RS14115	COG0583	DNA-binding transcription factor activity
SporoP8_RS14120	COG2814	Major facilitator Superfamily
SporoP8_RS14125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS14130	COG0450	alkyl hydroperoxide reductase
SporoP8_RS14145	COG1176	ABC-type spermidine putrescine transport system, permease component I
SporoP8_RS14150	COG1177	transmembrane transport
SporoP8_RS14160	COG0569	domain protein
SporoP8_RS14165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SporoP8_RS14190	COG0022	dehydrogenase e1 component
SporoP8_RS14225	COG0483	inositol monophosphate 1-phosphatase activity
SporoP8_RS14235	COG1217	gtp-binding protein TYPA
SporoP8_RS14245	COG4896	Protein conserved in bacteria
SporoP8_RS14250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SporoP8_RS14260	COG0772	Belongs to the SEDS family
SporoP8_RS14265	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SporoP8_RS14295	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SporoP8_RS14300	COG3336	cytochrome c oxidase
SporoP8_RS14320	COG2340	Cysteine-rich secretory protein family
SporoP8_RS14325	COG0527	aspartate kinase activity
SporoP8_RS14330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SporoP8_RS14335	COG3679	Belongs to the UPF0342 family
SporoP8_RS14345	COG4471	UPF0298 protein
SporoP8_RS14360	COG0742	ribosomal rna small subunit methyltransferase
SporoP8_RS14365	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SporoP8_RS14375	COG3480	Lon protease (S16) C-terminal proteolytic domain
SporoP8_RS14385	COG1399	metal-binding, possibly nucleic acid-binding protein
SporoP8_RS14390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SporoP8_RS14395	COG1024	Enoyl-CoA hydratase
SporoP8_RS14405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SporoP8_RS14410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SporoP8_RS14425	COG2001	Belongs to the MraZ family
SporoP8_RS14440	COG0768	penicillin binding
SporoP8_RS14445	COG0768	penicillin binding
SporoP8_RS14450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SporoP8_RS14460	COG0772	Belongs to the SEDS family
SporoP8_RS14465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SporoP8_RS14470	COG3879	Bacterial protein of unknown function (DUF881)
SporoP8_RS14475	COG3879	Bacterial protein of unknown function (DUF881)
SporoP8_RS14480	COG3856	small basic protein
SporoP8_RS14485	COG0849	cell division
SporoP8_RS14490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SporoP8_RS14500	COG1191	sigma factor activity
SporoP8_RS14505	COG1191	sigma factor activity
SporoP8_RS14515	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SporoP8_RS14525	COG0762	integral membrane protein
SporoP8_RS14535	COG3599	regulation of cell shape
SporoP8_RS14545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SporoP8_RS14550	COG0564	pseudouridine synthase activity
SporoP8_RS14555	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SporoP8_RS14565	COG0540	Belongs to the ATCase OTCase family
SporoP8_RS14575	COG0505	Belongs to the CarA family
SporoP8_RS14590	COG0167	dihydroorotate dehydrogenase activity
SporoP8_RS14620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SporoP8_RS14625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SporoP8_RS14640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SporoP8_RS14640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SporoP8_RS14645	COG0631	protein serine/threonine phosphatase activity
SporoP8_RS14650	COG2815	serine threonine protein kinase
SporoP8_RS14650	COG0515	serine threonine protein kinase
SporoP8_RS14660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SporoP8_RS14665	COG1564	THIamine pyrophosphokinase
SporoP8_RS14675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SporoP8_RS14680	COG1302	Protein conserved in bacteria
SporoP8_RS14685	COG1461	Dihydroxyacetone kinase
SporoP8_RS14690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SporoP8_RS14705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SporoP8_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
SporoP8_RS14715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SporoP8_RS14725	COG1196	nuclear chromosome segregation
SporoP8_RS14730	COG0552	protein localization to endoplasmic reticulum
SporoP8_RS14735	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SporoP8_RS14740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SporoP8_RS14750	COG1837	Belongs to the UPF0109 family
SporoP8_RS14755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SporoP8_RS14760	COG0336	Belongs to the RNA methyltransferase TrmD family
SporoP8_RS14765	COG0335	large ribosomal subunit rRNA binding
SporoP8_RS14775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SporoP8_RS14790	COG2257	FlhB HrpN YscU SpaS Family
SporoP8_RS14795	COG0045	succinate-CoA ligase (ADP-forming) activity
SporoP8_RS14800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SporoP8_RS14805	COG0758	DNA mediated transformation
SporoP8_RS14810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SporoP8_RS14820	COG4974	Belongs to the 'phage' integrase family
SporoP8_RS14830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SporoP8_RS14840	COG1815	bacterial-type flagellum-dependent cell motility
SporoP8_RS14845	COG1558	bacterial-type flagellum-dependent cell motility
SporoP8_RS14850	COG1677	Flagellar hook-basal body complex protein FliE
SporoP8_RS14855	COG1766	The M ring may be actively involved in energy transduction
SporoP8_RS14860	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SporoP8_RS14870	COG1157	protein secretion by the type III secretion system
SporoP8_RS14875	COG2882	bacterial-type flagellum organization
SporoP8_RS14890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SporoP8_RS14900	COG4786	Flagellar basal body rod
SporoP8_RS14905	COG1582	Flagellar protein (FlbD)
SporoP8_RS14910	COG1580	Controls the rotational direction of flagella during chemotaxis
SporoP8_RS14915	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SporoP8_RS14920	COG1776	CheC inhibitor of MCP methylation
SporoP8_RS14920	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SporoP8_RS14925	COG2201	protein-glutamate methylesterase activity
SporoP8_RS14930	COG3190	flagellar
SporoP8_RS14935	COG1338	Plays a role in the flagellum-specific transport system
SporoP8_RS14940	COG1987	bacterial-type flagellum assembly
SporoP8_RS14945	COG1684	flagellar biosynthetic protein fliR
SporoP8_RS14950	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SporoP8_RS14955	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SporoP8_RS14960	COG1419	protein localization to endoplasmic reticulum
SporoP8_RS14965	COG0455	bacterial-type flagellum organization
SporoP8_RS14970	COG2201	protein-glutamate methylesterase activity
SporoP8_RS14975	COG0643	Histidine kinase
SporoP8_RS14975	COG2198	Histidine kinase
SporoP8_RS14985	COG1776	CheC inhibitor of MCP methylation
SporoP8_RS14990	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SporoP8_RS14995	COG1191	sigma factor activity
SporoP8_RS15015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SporoP8_RS15020	COG0528	UMP kinase activity
SporoP8_RS15025	COG0233	cytoplasmic translational termination
SporoP8_RS15030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SporoP8_RS15035	COG4589	Belongs to the CDS family
SporoP8_RS15045	COG0750	zinc metalloprotease
SporoP8_RS15055	COG2176	DNA-directed DNA polymerase activity
SporoP8_RS15065	COG0195	Participates in both transcription termination and antitermination
SporoP8_RS15070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SporoP8_RS15075	COG1358	cellular component organization or biogenesis
SporoP8_RS15085	COG1550	Protein conserved in bacteria
SporoP8_RS15095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SporoP8_RS15100	COG0196	riboflavin kinase activity
SporoP8_RS15105	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SporoP8_RS15115	COG0612	Peptidase, M16
SporoP8_RS15130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SporoP8_RS15135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SporoP8_RS15145	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SporoP8_RS15150	COG1674	ftsk spoiiie
SporoP8_RS15155	COG1744	ABC transporter substrate-binding protein PnrA-like
SporoP8_RS15160	COG3845	ABC transporter
SporoP8_RS15165	COG4603	Belongs to the binding-protein-dependent transport system permease family
SporoP8_RS15170	COG1079	Belongs to the binding-protein-dependent transport system permease family
SporoP8_RS15175	COG0612	Peptidase, M16
SporoP8_RS15180	COG0612	Peptidase, M16
SporoP8_RS15185	COG0300	oxidoreductase activity
SporoP8_RS15195	COG1426	Protein conserved in bacteria
SporoP8_RS15200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SporoP8_RS15210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SporoP8_RS15220	COG1692	metallophosphoesterase
SporoP8_RS15225	COG2359	stage V sporulation protein S
SporoP8_RS15230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SporoP8_RS15235	COG4550	Control of competence regulator ComK, YlbF/YmcA
SporoP8_RS15250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SporoP8_RS15255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SporoP8_RS15260	COG2267	carboxylic ester hydrolase activity
SporoP8_RS15265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SporoP8_RS15270	COG1923	regulation of RNA biosynthetic process
SporoP8_RS15275	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SporoP8_RS15290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SporoP8_RS15310	COG3763	UPF0154 protein
SporoP8_RS15315	COG1073	alpha beta
SporoP8_RS15335	COG1366	Belongs to the anti-sigma-factor antagonist family
SporoP8_RS15345	COG2321	neutral zinc metallopeptidase
SporoP8_RS15350	COG2223	nitrite transmembrane transporter activity
SporoP8_RS15355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SporoP8_RS15360	COG5609	conserved protein (DUF2294)
SporoP8_RS15365	COG3383	formate dehydrogenase (NAD+) activity
SporoP8_RS15370	COG2427	Protein of unknown function (DUF1641)
SporoP8_RS15375	COG0788	formyltetrahydrofolate deformylase activity
SporoP8_RS15380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SporoP8_RS15385	COG2766	serine protein kinase
SporoP8_RS15390	COG2718	Belongs to the UPF0229 family
SporoP8_RS15395	COG2719	SpoVR family
SporoP8_RS15400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SporoP8_RS15405	COG0765	amino acid transport
SporoP8_RS15410	COG1126	abc transporter atp-binding protein
SporoP8_RS15420	COG4120	Belongs to the binding-protein-dependent transport system permease family
SporoP8_RS15425	COG1122	ATPase activity
SporoP8_RS15430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SporoP8_RS15435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SporoP8_RS15440	COG2313	pseudouridylate synthase activity
SporoP8_RS15445	COG0708	Exodeoxyribonuclease III
SporoP8_RS15455	COG2807	transmembrane transport
SporoP8_RS15465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SporoP8_RS15470	COG2233	PERMEase
SporoP8_RS15475	COG0667	Aldo Keto reductase
SporoP8_RS15490	COG0735	belongs to the Fur family
SporoP8_RS15495	COG4974	Belongs to the 'phage' integrase family
SporoP8_RS15505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SporoP8_RS15525	COG0697	spore germination
SporoP8_RS15530	COG0019	diaminopimelate decarboxylase activity
SporoP8_RS15540	COG1547	Domain of unknown function (DUF309)
SporoP8_RS15550	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SporoP8_RS15555	COG1686	Belongs to the peptidase S11 family
SporoP8_RS15560	COG1187	pseudouridine synthase activity
SporoP8_RS15565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SporoP8_RS15570	COG1333	cytochrome c biogenesis protein
SporoP8_RS15575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SporoP8_RS15580	COG0745	RESPONSE REGULATOR receiver
SporoP8_RS15585	COG5002	protein histidine kinase activity
SporoP8_RS15590	COG1595	DNA-templated transcription, initiation
SporoP8_RS15600	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SporoP8_RS15605	COG1141	Ferredoxin
SporoP8_RS15610	COG4955	Helix-turn-helix domain
SporoP8_RS15615	COG0514	ATP-dependent DNA helicase (RecQ)
SporoP8_RS15625	COG1408	metallophosphoesterase
SporoP8_RS15630	COG0492	ferredoxin-NADP+ reductase activity
SporoP8_RS15635	COG2339	peptidase activity
SporoP8_RS15640	COG3409	Peptidoglycan-binding domain 1 protein
SporoP8_RS15640	COG3773	Cell wall hydrolase
SporoP8_RS15645	COG2959	enzyme of heme biosynthesis
SporoP8_RS15650	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
SporoP8_RS15655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SporoP8_RS15665	COG0539	negative regulation of cytoplasmic translation
SporoP8_RS15670	COG1160	GTP binding
SporoP8_RS15690	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SporoP8_RS15725	COG0105	UTP biosynthetic process
SporoP8_RS15730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SporoP8_RS15745	COG4401	Chorismate mutase type I
SporoP8_RS15755	COG0287	Prephenate dehydrogenase
SporoP8_RS15760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SporoP8_RS15780	COG0723	plastoquinol--plastocyanin reductase activity
SporoP8_RS15795	COG4347	Protein of unknown function (DUF1405)
SporoP8_RS15800	COG2738	Putative neutral zinc metallopeptidase
SporoP8_RS15810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SporoP8_RS15815	COG1694	Mazg nucleotide pyrophosphohydrolase
SporoP8_RS15825	COG0438	transferase activity, transferring glycosyl groups
SporoP8_RS15835	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SporoP8_RS15835	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SporoP8_RS15845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SporoP8_RS15850	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SporoP8_RS15855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SporoP8_RS15855	COG1199	ATP-dependent helicase activity
SporoP8_RS15870	COG3935	DnaD domain protein
SporoP8_RS15875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SporoP8_RS15885	COG4499	WXG100 protein secretion system (Wss), protein YukC
SporoP8_RS15885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SporoP8_RS15900	COG1205	dead DEAH box helicase
SporoP8_RS15900	COG1111	helicase
SporoP8_RS15905	COG0737	Belongs to the 5'-nucleotidase family
SporoP8_RS15915	COG3189	MarR family transcriptional regulator
SporoP8_RS15940	COG3359	exonuclease
SporoP8_RS15965	COG0116	Belongs to the methyltransferase superfamily
SporoP8_RS15970	COG1199	ATP-dependent helicase activity
SporoP8_RS15980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SporoP8_RS16025	COG0625	glutathione transferase activity
SporoP8_RS16050	COG0328	RNA-DNA hybrid ribonuclease activity
SporoP8_RS16065	COG1380	Effector of murein hydrolase LrgA
SporoP8_RS16070	COG1346	cytolysis
SporoP8_RS16075	COG1827	regulation of RNA biosynthetic process
SporoP8_RS16080	COG1104	cysteine desulfurase activity
SporoP8_RS16085	COG0157	Belongs to the NadC ModD family
SporoP8_RS16095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SporoP8_RS16100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SporoP8_RS16105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SporoP8_RS16115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SporoP8_RS16120	COG1959	2 iron, 2 sulfur cluster binding
SporoP8_RS16125	COG1104	cysteine desulfurase activity
SporoP8_RS16140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SporoP8_RS16145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SporoP8_RS16150	COG4472	Bacterial protein of unknown function (DUF965)
SporoP8_RS16155	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SporoP8_RS16160	COG3906	Belongs to the UPF0473 family
SporoP8_RS16165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SporoP8_RS16170	COG4122	O-methyltransferase activity
SporoP8_RS16175	COG0572	uridine kinase
SporoP8_RS16180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SporoP8_RS16200	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SporoP8_RS16205	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SporoP8_RS16215	COG1534	Rna-binding protein
SporoP8_RS16225	COG1713	HD superfamily hydrolase involved in NAD metabolism
SporoP8_RS16230	COG0799	negative regulation of ribosome biogenesis
SporoP8_RS16235	COG2226	methyltransferase
SporoP8_RS16240	COG1555	photosystem II stabilization
SporoP8_RS16240	COG1596	polysaccharide export
SporoP8_RS16245	COG2131	deaminase
SporoP8_RS16250	COG0658	competence protein
SporoP8_RS16250	COG2333	competence protein COMEC
SporoP8_RS16260	COG1466	dna polymerase III delta subunit
SporoP8_RS16270	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SporoP8_RS16280	COG0481	GTPase activity
SporoP8_RS16285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SporoP8_RS16295	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SporoP8_RS16300	COG0443	Heat shock 70 kDa protein
SporoP8_RS16310	COG2264	protein methyltransferase activity
SporoP8_RS16315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SporoP8_RS16320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SporoP8_RS16330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SporoP8_RS16335	COG1030	water channel activity
SporoP8_RS16340	COG4864	UPF0365 protein
SporoP8_RS16360	COG1702	phosphate starvation-inducible protein PhoH
SporoP8_RS16365	COG1480	7TM receptor with intracellular HD hydrolase
SporoP8_RS16370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SporoP8_RS16375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SporoP8_RS16390	COG1381	Involved in DNA repair and RecF pathway recombination
SporoP8_RS16400	COG0517	IMP dehydrogenase activity
SporoP8_RS16410	COG0358	DNA primase activity