locus-tag	class	description
GJE18_RS00015	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
GJE18_RS00025	ENOG4107ETC	gas vesicle protein
GJE18_RS00050	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
GJE18_RS00060	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GJE18_RS00065	ENOG4105C84	Histidine ammonia-lyase
GJE18_RS00070	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GJE18_RS00075	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GJE18_RS00100	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GJE18_RS00105	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GJE18_RS00115	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GJE18_RS00120	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GJE18_RS00125	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GJE18_RS00130	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GJE18_RS00135	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
GJE18_RS00140	ENOG4105FBA	Phospholipase Carboxylesterase
GJE18_RS00145	ENOG4107XC4	flavin reductase domain protein, FMN-binding
GJE18_RS00155	ENOG41090MY	MarR family Transcriptional regulator
GJE18_RS00175	ENOG4108YYC	ycei family
GJE18_RS00185	ENOG4105HFU	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
GJE18_RS00190	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GJE18_RS00195	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GJE18_RS00200	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GJE18_RS00210	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GJE18_RS00240	ENOG4105C28	cystathionine
GJE18_RS00245	ENOG4105C28	cystathionine
GJE18_RS00250	ENOG4105FA0	parb-like partition protein
GJE18_RS00255	ENOG4105D8X	mechanosensitive ion channel
GJE18_RS00260	ENOG4105VDK	protein, conserved in bacteria
GJE18_RS00265	ENOG4105C3G	gtp-binding protein
GJE18_RS00275	ENOG4108RYK	Nad-dependent epimerase dehydratase
GJE18_RS00280	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GJE18_RS00285	ENOG4108UUM	single-stranded DNA-binding protein
GJE18_RS00290	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GJE18_RS00315	ENOG4105BZW	Glycerate kinase
GJE18_RS00325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GJE18_RS00330	ENOG41062D9	Histidine kinase
GJE18_RS00340	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GJE18_RS00355	ENOG4108JU3	Alkyl hydroperoxide reductase
GJE18_RS00360	ENOG4105D3R	alkyl hydroperoxide reductase
GJE18_RS00370	ENOG4108DBC	nitroreductase
GJE18_RS00375	ENOG4107R6U	sodium dicarboxylate symporter
GJE18_RS00380	ENOG41080HI	glycine oxidase
GJE18_RS00400	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
GJE18_RS00405	ENOG4105C2W	permease
GJE18_RS00410	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GJE18_RS00415	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GJE18_RS00455	ENOG4105D7K	pfkb domain protein
GJE18_RS00470	ENOG4106AM8	polysaccharide lyase family 8
GJE18_RS00490	ENOG4105WD1	Membrane
GJE18_RS00500	ENOG4108V5C	ABC transporter
GJE18_RS00545	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
GJE18_RS00550	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GJE18_RS00555	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GJE18_RS00560	ENOG4108RZA	ABC transporter
GJE18_RS00565	ENOG4108S9F	abc transporter, atp-binding protein
GJE18_RS00580	ENOG41080TC	multidrug resistance protein
GJE18_RS00610	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GJE18_RS00615	ENOG4105VRS	hydrolase family 18
GJE18_RS00710	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GJE18_RS00715	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GJE18_RS00720	ENOG4105C8J	)-transporter
GJE18_RS00725	ENOG4105EBR	Carboxylesterase
GJE18_RS00740	ENOG4105C28	cystathionine
GJE18_RS00760	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GJE18_RS00775	ENOG4107R11	Transcriptional regulator
GJE18_RS00780	ENOG4105CBC	glutamate synthase
GJE18_RS00785	ENOG4105BZ8	glutamate synthase
GJE18_RS00795	ENOG4105C5Y	PTS System
GJE18_RS00800	ENOG4105CG3	alpha amylase, catalytic region
GJE18_RS00805	ENOG4107414	GntR family transcriptional regulator
GJE18_RS00820	ENOG4105C6E	dna polymerase iii
GJE18_RS00825	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GJE18_RS00830	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GJE18_RS00855	ENOG4105CXN	decarboxylase
GJE18_RS00860	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GJE18_RS00865	ENOG4105X0R	protein from nitrogen regulatory protein P-II
GJE18_RS00870	ENOG4105FA2	dna polymerase iii
GJE18_RS00875	ENOG4105MA4	psp1 domain protein
GJE18_RS00885	ENOG41060K3	Methyltransferase
GJE18_RS00890	ENOG4105VC4	domain protein
GJE18_RS00895	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GJE18_RS00900	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GJE18_RS00905	ENOG4105F8V	Hydrolase, tatD family
GJE18_RS00910	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
GJE18_RS00915	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GJE18_RS00920	ENOG4105W42	Veg protein
GJE18_RS00925	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GJE18_RS00930	ENOG4105DFT	pur operon repressor
GJE18_RS00935	ENOG4105KME	endoribonuclease L-psp
GJE18_RS00940	ENOG4105K4W	Could be involved in septation (By similarity)
GJE18_RS00945	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GJE18_RS00950	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GJE18_RS00960	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GJE18_RS00965	ENOG4108JA2	transcriptioN-repair coupling factor
GJE18_RS00975	ENOG4108IY2	MazG family
GJE18_RS00980	ENOG41082I2	s4 domain protein
GJE18_RS00990	ENOG41060GV	RNA binding s1 domain protein
GJE18_RS00995	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GJE18_RS01000	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GJE18_RS01005	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GJE18_RS01010	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GJE18_RS01015	ENOG4105C6T	cysteine synthase
GJE18_RS01025	ENOG4105KRF	dihydroneopterin aldolase
GJE18_RS01030	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GJE18_RS01035	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GJE18_RS01130	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GJE18_RS01135	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
GJE18_RS01145	ENOG4105D9N	nucleoside
GJE18_RS01155	ENOG4108Z0C	Uvrb UvrC protein
GJE18_RS01160	ENOG41066A3	ATP guanido phosphotransferase
GJE18_RS01170	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GJE18_RS01175	ENOG4105CTP	PilT protein domain protein
GJE18_RS01180	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GJE18_RS01195	ENOG4105D7W	serine acetyltransferase
GJE18_RS01200	ENOG4105C8N	cysteinyl-tRNA synthetase
GJE18_RS01205	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GJE18_RS01215	ENOG4105M0M	Tetracycline resistance protein
GJE18_RS01225	ENOG4107FTN	50S ribosomal protein L33
GJE18_RS01230	ENOG410683Z	Preprotein translocase SecE subunit
GJE18_RS01235	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GJE18_RS01240	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GJE18_RS01245	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GJE18_RS01250	ENOG4108VZM	50s ribosomal protein L10
GJE18_RS01260	ENOG4107Y49	methyltransferase
GJE18_RS01270	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GJE18_RS01280	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GJE18_RS01285	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GJE18_RS01310	ENOG4105EXW	epimerase dehydratase
GJE18_RS01315	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GJE18_RS01320	ENOG4105EWC	Purine nucleoside phosphorylase
GJE18_RS01335	ENOG4108V4B	ThiJ pfpI
GJE18_RS01345	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
GJE18_RS01355	ENOG4105ZMH	deoxynucleoside kinase
GJE18_RS01365	ENOG4108Z6B	deaminase
GJE18_RS01370	ENOG410667J	hydrolase
GJE18_RS01375	ENOG4107YFT	Nadph-dependent fmn reductase
GJE18_RS01385	ENOG4107YEI	lmbE family
GJE18_RS01395	ENOG4106G6Q	Transcriptional regulator
GJE18_RS01400	ENOG4105CI1	PTS System
GJE18_RS01415	ENOG4108VA3	3-hexulose-6-phosphate synthase
GJE18_RS01425	ENOG4107F3J	Amp-dependent synthetase and ligase
GJE18_RS01430	ENOG4105CHU	acetyl-coa acetyltransferase
GJE18_RS01455	ENOG4105DWF	phosphomethylpyrimidine kinase
GJE18_RS01460	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GJE18_RS01470	ENOG4105M08	Membrane
GJE18_RS01475	ENOG4105CUB	amino acid
GJE18_RS01490	ENOG4105CW7	secretion protein, HlyD family
GJE18_RS01495	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GJE18_RS01500	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
GJE18_RS01505	ENOG4108IJ2	phosphate acetyltransferase
GJE18_RS01515	ENOG4107R7I	amino acid
GJE18_RS01530	ENOG4105C8P	)-transporter
GJE18_RS01535	ENOG4105QAT	UPF0741 protein
GJE18_RS01540	ENOG4108WS4	fmn reductase
GJE18_RS01550	ENOG4105DCI	Phosphohydrolase
GJE18_RS01555	ENOG4108XFG	YwhD family
GJE18_RS01570	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GJE18_RS01575	ENOG4105EHG	Permease protein
GJE18_RS01580	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GJE18_RS01630	ENOG4105C8S	subunit m
GJE18_RS01635	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
GJE18_RS01640	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GJE18_RS01650	ENOG4105IMY	monovalent cation H antiporter subunit E
GJE18_RS01655	ENOG410684G	monovalent cation H antiporter subunit F
GJE18_RS01660	ENOG4105KJM	monovalent cation h antiporter subunit g
GJE18_RS01670	ENOG4105DSE	periplasmic solute binding protein
GJE18_RS01675	ENOG4105CC5	ABC transporter
GJE18_RS01680	ENOG4105DIK	(ABC) transporter
GJE18_RS01695	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
GJE18_RS01700	ENOG4105EY8	ABC transporter
GJE18_RS01715	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
GJE18_RS01725	ENOG4105BZ1	(ABC) transporter
GJE18_RS01750	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
GJE18_RS01755	ENOG4105E0A	ABC, transporter
GJE18_RS01760	ENOG4105DQ5	transport system permease protein
GJE18_RS01765	ENOG4105EHG	Permease protein
GJE18_RS01795	ENOG4107GRR	phosphate transport regulator
GJE18_RS01800	ENOG4105CJ3	phosphate transporter
GJE18_RS01805	ENOG4105VRS	hydrolase family 18
GJE18_RS01825	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GJE18_RS01830	ENOG4105D06	uba thif-type nad fad binding protein
GJE18_RS01835	ENOG4105CDY	transcriptional regulatory protein
GJE18_RS01850	ENOG4105S8Q	sugar efflux transporter
GJE18_RS01855	ENOG4105SXS	Protein of unknown function (DUF456)
GJE18_RS01885	ENOG4108URH	decarboxylase
GJE18_RS01890	ENOG4107XJU	UPF0178 protein
GJE18_RS01910	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GJE18_RS01915	ENOG4108JJ9	ABC, transporter
GJE18_RS01920	ENOG4108JJ8	(ABC) transporter
GJE18_RS01925	ENOG4105K56	Transcriptional regulator
GJE18_RS01930	ENOG4105CKI	cobalamin synthesis protein
GJE18_RS01935	ENOG4107QM2	Aldo Keto reductase
GJE18_RS01945	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GJE18_RS01965	ENOG4107SJB	teichoic acid biosynthesis
GJE18_RS01970	ENOG4108Z66	YbaK ebsC protein
GJE18_RS01975	ENOG4105E98	transcriptional regulator DeoR family
GJE18_RS01980	ENOG4105DE4	1-phosphofructokinase
GJE18_RS01985	ENOG4105DM4	PTS System
GJE18_RS01990	ENOG4105C37	(CBS) domain
GJE18_RS01995	ENOG4105CKK	Glycosyl transferase, family 2
GJE18_RS02010	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GJE18_RS02015	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
GJE18_RS02025	ENOG4105DDQ	anthranilate synthase
GJE18_RS02055	ENOG4105E0M	Sulfatase
GJE18_RS02065	ENOG4105C5H	ABC transporter
GJE18_RS02070	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GJE18_RS02075	ENOG4108IJ8	ABC transporter
GJE18_RS02080	ENOG4105E90	ABC transporter
GJE18_RS02085	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GJE18_RS02090	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
GJE18_RS02100	ENOG4105DUX	Transporter
GJE18_RS02105	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GJE18_RS02115	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
GJE18_RS02120	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GJE18_RS02125	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GJE18_RS02155	ENOG4105BZW	Glycerate kinase
GJE18_RS02160	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GJE18_RS02185	ENOG4107DDB	Cysteine protease able to
GJE18_RS02190	ENOG4105ESV	Glycosyl transferase, family 4
GJE18_RS02195	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GJE18_RS02200	ENOG4105EPR	degv family
GJE18_RS02215	ENOG4105MS2	ribosomal subunit Interface protein
GJE18_RS02220	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GJE18_RS02245	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GJE18_RS02250	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GJE18_RS02260	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
GJE18_RS02265	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GJE18_RS02270	ENOG4108S4C	acetyltransferase
GJE18_RS02280	ENOG4105C3M	thioredoxin reductase
GJE18_RS02285	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GJE18_RS02290	ENOG4105CHW	UPF0052 protein
GJE18_RS02295	ENOG4105CIE	May be required for sporulation (By similarity)
GJE18_RS02330	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
GJE18_RS02340	ENOG4108Z7F	N-acetyltransferase
GJE18_RS02345	ENOG4105ECP	epimerase
GJE18_RS02365	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GJE18_RS02370	ENOG4105BZA	Phosphoglycerate kinase
GJE18_RS02375	ENOG4105CP7	Triose-phosphate isomerase
GJE18_RS02380	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GJE18_RS02385	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GJE18_RS02395	ENOG4105XZU	Preprotein translocase, subunit SecG
GJE18_RS02405	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GJE18_RS02425	ENOG4107R08	Integrase
GJE18_RS02535	ENOG4105FF2	Type I DHQase
GJE18_RS02545	ENOG4105SZ6	Thioredoxin
GJE18_RS02550	ENOG41080E8	Transcriptional regulator, Spx MgsR family
GJE18_RS02570	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GJE18_RS02575	ENOG4108UMI	ABC transporter, permease
GJE18_RS02580	ENOG4105D01	(LipO)protein
GJE18_RS02590	ENOG4105C3K	feS assembly ATPase SufC
GJE18_RS02595	ENOG4105JRK	feS assembly protein SufD
GJE18_RS02600	ENOG4105C9B	Cysteine desulfurase
GJE18_RS02605	ENOG4108UNV	SUF system FeS assembly protein, NifU family
GJE18_RS02610	ENOG4105DIW	FeS assembly protein SUFB
GJE18_RS02620	ENOG4105EA8	2-Nitropropane dioxygenase
GJE18_RS02630	ENOG4105I3N	Conserved Protein
GJE18_RS02640	ENOG4107R8B	5'-nucleotidase
GJE18_RS02650	ENOG4105MMD	transcriptional regulator
GJE18_RS02665	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
GJE18_RS02670	ENOG4105C5I	Dehydrogenase
GJE18_RS02685	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GJE18_RS02695	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
GJE18_RS02700	ENOG41083MR	nifu domain-containing protein
GJE18_RS02720	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GJE18_RS02725	ENOG4105CEP	NADH dehydrogenase
GJE18_RS02730	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GJE18_RS02740	ENOG4105KA0	thioesterase Superfamily protein
GJE18_RS02755	ENOG4105W4C	monovalent cation H antiporter subunit F
GJE18_RS02765	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GJE18_RS02770	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GJE18_RS02780	ENOG4105D65	subunit l
GJE18_RS02790	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GJE18_RS02815	ENOG4105C26	Dehydrogenase
GJE18_RS02820	ENOG4105C8Y	Acetylornithine aminotransferase
GJE18_RS02825	ENOG4105D82	Glutamate dehydrogenase
GJE18_RS02830	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GJE18_RS02835	ENOG4105CH7	arginosuccinase
GJE18_RS02840	ENOG4105CDH	Citrulline--aspartate ligase
GJE18_RS02850	ENOG4108ZX0	Signal peptidase I
GJE18_RS02860	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GJE18_RS02870	ENOG4105ERH	Fumarylacetoacetate hydrolase
GJE18_RS02880	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GJE18_RS02885	ENOG4108KP7	hydrolase
GJE18_RS02890	ENOG4105VG1	fes assembly suf system protein
GJE18_RS02895	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GJE18_RS02910	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GJE18_RS02920	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GJE18_RS02925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GJE18_RS02935	ENOG4108JQ7	(ABC) transporter
GJE18_RS02945	ENOG4105C31	Tryptophanyl-tRNA synthetase
GJE18_RS02950	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
GJE18_RS02955	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GJE18_RS02965	ENOG4105DPN	Oligoendopeptidase f
GJE18_RS02970	ENOG4105T58	Dithiol-disulfide isomerase
GJE18_RS02975	ENOG4108Z18	K06886 hemoglobin
GJE18_RS02980	ENOG4105MIX	Adenylate cyclase
GJE18_RS02985	ENOG4106EFP	UPF0738 protein
GJE18_RS02995	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GJE18_RS03000	ENOG4105EMS	pseudouridine synthase
GJE18_RS03005	ENOG4105CJW	magnesium transporter
GJE18_RS03020	ENOG4105C02	permease
GJE18_RS03025	ENOG4105BZG	amino acid carrier protein
GJE18_RS03045	ENOG4108PK2	permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence
GJE18_RS03050	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
GJE18_RS03055	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GJE18_RS03065	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GJE18_RS03070	ENOG4107TS3	membrane protein, TerC
GJE18_RS03075	ENOG4105C0H	protease
GJE18_RS03085	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GJE18_RS03145	ENOG41083J0	(ABC) transporter
GJE18_RS03150	ENOG4105C4B	ABC transporter, permease
GJE18_RS03155	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GJE18_RS03160	ENOG4105E4F	Isochorismate synthase
GJE18_RS03165	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GJE18_RS03170	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GJE18_RS03175	ENOG4108IPT	Naphthoate synthase
GJE18_RS03180	ENOG4105CHM	Aminotransferase
GJE18_RS03185	ENOG4108TGC	Acyltransferase
GJE18_RS03195	ENOG4108HPG	-acetyltransferase
GJE18_RS03205	ENOG4108KGH	TRANSCRIPTIONal
GJE18_RS03210	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
GJE18_RS03235	ENOG4107SJB	teichoic acid biosynthesis
GJE18_RS03240	ENOG4105CPK	Glycosyl transferase (Group 1
GJE18_RS03260	ENOG4105EY8	ABC transporter
GJE18_RS03275	ENOG4105CCU	oxidase (Subunit III)
GJE18_RS03285	ENOG4105E2S	oxidase) subunit II
GJE18_RS03295	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GJE18_RS03300	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GJE18_RS03305	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GJE18_RS03315	ENOG4105C8V	SAICAR synthetase
GJE18_RS03320	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
GJE18_RS03330	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
GJE18_RS03340	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GJE18_RS03345	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GJE18_RS03350	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GJE18_RS03355	ENOG4105C12	Phosphoribosylglycinamide synthetase
GJE18_RS03365	ENOG4108JJB	ABC transporter
GJE18_RS03370	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
GJE18_RS03380	ENOG4105DR4	Methyltransferase
GJE18_RS03390	ENOG4105KRI	phosphocarrier protein (HPr
GJE18_RS03395	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GJE18_RS03400	ENOG4105VW4	glutaredoxin 3
GJE18_RS03415	ENOG4107ZYR	domain protein
GJE18_RS03425	ENOG4105CN5	Metallo-Beta-Lactamase
GJE18_RS03430	ENOG4106148	UPF0356 protein
GJE18_RS03440	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GJE18_RS03455	ENOG4105CPP	Dehydrogenase, E1 component
GJE18_RS03460	ENOG4105C7S	Dehydrogenase
GJE18_RS03465	ENOG4107QN2	dihydrolipoyl dehydrogenase
GJE18_RS03470	ENOG4105WBI	UPF0223 protein
GJE18_RS03490	ENOG4105D38	putrescine abc transporter
GJE18_RS03495	ENOG4107RUE	extracellular solute-binding protein family 1
GJE18_RS03510	ENOG4108WQ8	UPF0637 protein
GJE18_RS03515	ENOG4105ECY	inositol monophosphatase
GJE18_RS03525	ENOG4105CI3	gtp-binding protein typa
GJE18_RS03530	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GJE18_RS03545	ENOG4105ZPI	UPF0358 protein
GJE18_RS03550	ENOG4105CNI	cell division protein FtsW
GJE18_RS03565	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GJE18_RS03590	ENOG4105WUC	UPF0298 protein
GJE18_RS03600	ENOG4106H78	methyltransferase
GJE18_RS03605	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GJE18_RS03610	ENOG4105CDE	UPF0348 protein
GJE18_RS03620	ENOG41067VY	50S ribosomal protein L32
GJE18_RS03625	ENOG4108RWN	rrna methyltransferase
GJE18_RS03630	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GJE18_RS03635	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GJE18_RS03640	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GJE18_RS03655	ENOG4105DCG	PHP domain protein
GJE18_RS03660	ENOG4105C98	muts2 protein
GJE18_RS03665	ENOG4105K63	Thioredoxin
GJE18_RS03670	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GJE18_RS03675	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
GJE18_RS03685	ENOG4105E33	succinate dehydrogenase
GJE18_RS03710	ENOG4105DR5	peptidase
GJE18_RS03735	ENOG4105VTR	Integrase
GJE18_RS03830	ENOG4108UUM	single-stranded DNA-binding protein
GJE18_RS03850	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GJE18_RS03930	ENOG4105EFC	phage portal protein HK97 family
GJE18_RS03985	ENOG4105DR5	peptidase
GJE18_RS04025	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
GJE18_RS04060	ENOG4105CZN	Potassium uptake protein
GJE18_RS04075	ENOG4108YG3	N-acetyltransferase
GJE18_RS04080	ENOG41074B2	UPF0747 protein
GJE18_RS04085	ENOG4108V6E	Cell division protein mraZ
GJE18_RS04090	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GJE18_RS04095	ENOG41068DC	Essential cell division protein (By similarity)
GJE18_RS04100	ENOG4105CJN	penicillin-binding protein
GJE18_RS04120	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GJE18_RS04125	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GJE18_RS04130	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GJE18_RS04135	ENOG4105DFA	alanine racemase domain protein
GJE18_RS04140	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
GJE18_RS04145	ENOG41067XK	integral membrane protein
GJE18_RS04170	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GJE18_RS04175	ENOG4105C34	Pseudouridine synthase
GJE18_RS04180	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
GJE18_RS04190	ENOG4105CXT	aspartate transcarbamylase
GJE18_RS04195	ENOG4105CD3	dihydroorotase
GJE18_RS04200	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GJE18_RS04205	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GJE18_RS04215	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
GJE18_RS04220	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GJE18_RS04225	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GJE18_RS04245	ENOG41067UH	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GJE18_RS04250	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GJE18_RS04255	ENOG4105C25	Primosomal protein n'
GJE18_RS04260	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GJE18_RS04265	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GJE18_RS04270	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GJE18_RS04275	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GJE18_RS04295	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GJE18_RS04300	ENOG4105DJV	ribulose-phosphate 3-epimerase
GJE18_RS04305	ENOG4105FJ0	thiamine
GJE18_RS04315	ENOG4108ZAA	Alkaline-shock protein
GJE18_RS04330	ENOG4105EJQ	L-serine dehydratase
GJE18_RS04335	ENOG4105CB5	ATP-dependent DNA helicase recG
GJE18_RS04340	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
GJE18_RS04345	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GJE18_RS04355	ENOG4105CHR	reductase
GJE18_RS04360	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GJE18_RS04365	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GJE18_RS04370	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GJE18_RS04375	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GJE18_RS04380	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
GJE18_RS04390	ENOG4105K5M	30s ribosomal protein S16
GJE18_RS04400	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GJE18_RS04405	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GJE18_RS04430	ENOG4105EJV	Membrane
GJE18_RS04435	ENOG4105EJV	Membrane
GJE18_RS04445	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GJE18_RS04450	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GJE18_RS04460	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GJE18_RS04465	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GJE18_RS04470	ENOG4105C79	DNA protecting protein DprA
GJE18_RS04475	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GJE18_RS04485	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GJE18_RS04495	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GJE18_RS04500	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
GJE18_RS04505	ENOG4105CE9	30S ribosomal protein S2
GJE18_RS04510	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GJE18_RS04515	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GJE18_RS04520	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GJE18_RS04525	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GJE18_RS04530	ENOG4105KNE	Phosphatidate cytidylyltransferase
GJE18_RS04535	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GJE18_RS04540	ENOG4105DZP	Membrane-associated zinc metalloprotease
GJE18_RS04545	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GJE18_RS04555	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GJE18_RS04560	ENOG4105CHV	Transcription elongation factor NusA
GJE18_RS04565	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
GJE18_RS04570	ENOG4105VHM	ribosomal protein
GJE18_RS04585	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GJE18_RS04590	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GJE18_RS04595	ENOG4105DTN	riboflavin biosynthesis protein ribF
GJE18_RS04605	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GJE18_RS04615	ENOG4105CN5	Metallo-Beta-Lactamase
GJE18_RS04625	ENOG4105FDP	GntR family transcriptional regulator
GJE18_RS04640	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
GJE18_RS04655	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GJE18_RS04660	ENOG4105CEV	competence damage-inducible protein
GJE18_RS04665	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GJE18_RS04670	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
GJE18_RS04690	ENOG4105D48	metallophosphoesterase
GJE18_RS04695	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GJE18_RS04700	ENOG4105DQU	oxidoreductase, subunit beta
GJE18_RS04710	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GJE18_RS04730	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GJE18_RS04745	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GJE18_RS04755	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GJE18_RS04765	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GJE18_RS04770	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GJE18_RS04775	ENOG4108V06	Glutathione peroxidase
GJE18_RS04780	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GJE18_RS04785	ENOG4105CXI	aluminum resistance protein
GJE18_RS04790	ENOG4105KV4	Transcriptional regulator
GJE18_RS04810	ENOG4108M15	ABC transporter
GJE18_RS04815	ENOG4105KCT	ABC transporter
GJE18_RS04820	ENOG4108ZGX	Histidine kinase
GJE18_RS04825	ENOG4108S01	response regulator
GJE18_RS04855	ENOG4105CFH	Aspartokinase
GJE18_RS04860	ENOG4105D6E	homoserine dehydrogenase
GJE18_RS04865	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GJE18_RS04870	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GJE18_RS04875	ENOG4105DQF	Hydrolase
GJE18_RS04885	ENOG4108IQI	permease
GJE18_RS04890	ENOG4105CH6	catalase
GJE18_RS04900	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GJE18_RS04905	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
GJE18_RS04910	ENOG4105K4I	Scp-like extracellular
GJE18_RS04940	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GJE18_RS04950	ENOG4105VPS	UPF0291 protein
GJE18_RS04955	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GJE18_RS04960	ENOG4105VXM	UPF0154 protein
GJE18_RS04970	ENOG4107RFY	SbcCD D subunit
GJE18_RS04975	ENOG4105EYH	Exonuclease
GJE18_RS04980	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GJE18_RS04985	ENOG4105C94	Transporter
GJE18_RS04990	ENOG4108I0Z	Aconitate hydratase
GJE18_RS05005	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GJE18_RS05010	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GJE18_RS05015	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GJE18_RS05025	ENOG4105CID	antiterminator
GJE18_RS05045	ENOG4108FKN	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GJE18_RS05050	ENOG4108RCF	TRANSCRIPTIONal
GJE18_RS05065	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GJE18_RS05070	ENOG4105EVN	Prephenate dehydrogenase
GJE18_RS05075	ENOG4105DER	m42 family
GJE18_RS05080	ENOG4108RMH	femAB family
GJE18_RS05085	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
GJE18_RS05095	ENOG4105DPN	Oligoendopeptidase f
GJE18_RS05100	ENOG4105DE4	1-phosphofructokinase
GJE18_RS05105	ENOG4105QNR	S1 RNA binding domain protein
GJE18_RS05110	ENOG4105C5H	ABC transporter
GJE18_RS05115	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GJE18_RS05120	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GJE18_RS05125	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GJE18_RS05130	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GJE18_RS05135	ENOG4105CH2	amidohydrolase
GJE18_RS05140	ENOG4108XFP	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GJE18_RS05145	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GJE18_RS05150	ENOG4105VEQ	Cold shock protein
GJE18_RS05170	ENOG4105CDW	Resistance protein
GJE18_RS05175	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GJE18_RS05180	ENOG4107T89	von Willebrand factor, type A
GJE18_RS05185	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
GJE18_RS05210	ENOG4105GR3	Histidine kinase
GJE18_RS05215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GJE18_RS05220	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GJE18_RS05250	ENOG4105E0X	reductase
GJE18_RS05260	ENOG4108RCR	degv family
GJE18_RS05265	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GJE18_RS05270	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GJE18_RS05275	ENOG4108Y6J	UPF0403 protein
GJE18_RS05280	ENOG4106QQ5	PBS lyase HEAT domain protein repeat-containing protein
GJE18_RS05295	ENOG4105VND	Ribonuclease
GJE18_RS05305	ENOG410890F	Dynamin family
GJE18_RS05310	ENOG4105FR1	rard protein
GJE18_RS05315	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GJE18_RS05330	ENOG4108UKS	UPF0398 protein
GJE18_RS05340	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
GJE18_RS05345	ENOG4105BZ4	penicillin-binding protein
GJE18_RS05355	ENOG4105CSM	endonuclease III
GJE18_RS05365	ENOG4105C5S	asparaginyl-tRNA synthetase
GJE18_RS05370	ENOG4105DVT	helicase
GJE18_RS05380	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GJE18_RS05385	ENOG4105CPK	Glycosyl transferase (Group 1
GJE18_RS05390	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
GJE18_RS05405	ENOG4105QKB	UPF0302 protein
GJE18_RS05410	ENOG41068YB	TPR repeat-containing protein
GJE18_RS05420	ENOG4105D49	3-dehydroquinate synthase
GJE18_RS05425	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GJE18_RS05430	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GJE18_RS05435	ENOG4105EAH	synthase
GJE18_RS05440	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GJE18_RS05450	ENOG4105K70	DNA-binding protein
GJE18_RS05455	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GJE18_RS05465	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GJE18_RS05470	ENOG4105CAT	Cytidine monophosphate kinase
GJE18_RS05475	ENOG4107RB3	L-asparaginase
GJE18_RS05480	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
GJE18_RS05490	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GJE18_RS05510	ENOG4105BZU	Histidine kinase
GJE18_RS05515	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GJE18_RS05520	ENOG4105FE9	pseudouridine synthase
GJE18_RS05525	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GJE18_RS05530	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GJE18_RS05540	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GJE18_RS05545	ENOG4105I3K	Ferric uptake regulator, Fur family
GJE18_RS05550	ENOG4108YZ4	nudix hydrolase
GJE18_RS05555	ENOG4105CPC	Aldo Keto reductase
GJE18_RS05565	ENOG4105II7	pyrroline-5-carboxylate reductase
GJE18_RS05570	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GJE18_RS05575	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GJE18_RS05590	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GJE18_RS05600	ENOG4108QEG	Membrane
GJE18_RS05605	ENOG4108Y6J	UPF0403 protein
GJE18_RS05610	ENOG4105C7S	Dehydrogenase
GJE18_RS05615	ENOG4105CPP	Dehydrogenase, E1 component
GJE18_RS05630	ENOG4105CKM	Branched-chain carboxylic acid kinase
GJE18_RS05640	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GJE18_RS05650	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GJE18_RS05660	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GJE18_RS05665	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GJE18_RS05675	ENOG4108ZSR	alkaline shock protein
GJE18_RS05680	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GJE18_RS05690	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GJE18_RS05695	ENOG4105DC7	peptidase M24
GJE18_RS05710	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
GJE18_RS05715	ENOG4105WZW	rhodanese family
GJE18_RS05720	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GJE18_RS05725	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GJE18_RS05735	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GJE18_RS05770	ENOG4105C5X	domain protein
GJE18_RS05795	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GJE18_RS05800	ENOG4105WDJ	50S ribosomal protein L33
GJE18_RS05805	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GJE18_RS05810	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GJE18_RS05815	ENOG4105E2Z	phosphate ABC transporter (Permease
GJE18_RS05820	ENOG4105C8U	phosphate abc transporter
GJE18_RS05825	ENOG4105EXS	phosphate abc transporter
GJE18_RS05830	ENOG4107RF6	penicillin-binding protein
GJE18_RS05835	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GJE18_RS05840	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GJE18_RS05845	ENOG4105N80	Ferric uptake regulator, Fur family
GJE18_RS05855	ENOG4105FDK	ABC transporter
GJE18_RS05860	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GJE18_RS05865	ENOG4105C1J	atp-dependent rna helicase
GJE18_RS05870	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GJE18_RS05875	ENOG4105EGD	dinuclear metal center protein, YbgI family
GJE18_RS05885	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GJE18_RS05890	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GJE18_RS05895	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GJE18_RS05905	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GJE18_RS05910	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
GJE18_RS05920	ENOG4105KG3	cytidine deaminase
GJE18_RS05930	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GJE18_RS05935	ENOG4105C9A	Phoh family
GJE18_RS05945	ENOG4105DI5	UPF0365 protein
GJE18_RS05950	ENOG4105F7J	membrane-bound serine protease
GJE18_RS05960	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GJE18_RS05965	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GJE18_RS05975	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GJE18_RS05985	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GJE18_RS05990	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
GJE18_RS05995	ENOG4105CSA	Coproporphyrinogen iii oxidase
GJE18_RS06005	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GJE18_RS06010	ENOG4105TQK	DNA polymerase iii, delta' subunit
GJE18_RS06020	ENOG4108UK2	deaminase
GJE18_RS06025	ENOG4105KQC	Competence protein
GJE18_RS06030	ENOG4108D32	Methyltransferase
GJE18_RS06035	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GJE18_RS06040	ENOG4108WF2	Metal Dependent Phosphohydrolase
GJE18_RS06050	ENOG410812S	Rna-binding protein
GJE18_RS06060	ENOG4105CQW	ribosome biogenesis GTPase YqeH
GJE18_RS06065	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
GJE18_RS06070	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GJE18_RS06075	ENOG4105C5A	transporter
GJE18_RS06080	ENOG4105E7W	lamb ycsf family protein
GJE18_RS06085	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GJE18_RS06090	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GJE18_RS06100	ENOG4105P4J	Allophanate hydrolase, subunit 1
GJE18_RS06105	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GJE18_RS06110	ENOG4105DBI	uridine monophosphokinase
GJE18_RS06115	ENOG4105CFP	Peptidase U32
GJE18_RS06120	ENOG4105XYU	peptidase (U32 family)
GJE18_RS06130	ENOG4105VPH	UPF0473 protein
GJE18_RS06135	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GJE18_RS06140	ENOG4105VBH	UPF0297 protein
GJE18_RS06150	ENOG4105C7H	Helicase, RecD TraA family
GJE18_RS06160	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GJE18_RS06165	ENOG4105C3J	Cysteine desulfurase
GJE18_RS06170	ENOG4105DEN	Luciferase family
GJE18_RS06195	ENOG4105D1H	recombination factor protein RarA
GJE18_RS06200	ENOG4105CUZ	uba thif-type nad fad binding protein
GJE18_RS06210	ENOG4105C9M	aspartyl-trna synthetase
GJE18_RS06220	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GJE18_RS06225	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GJE18_RS06235	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GJE18_RS06240	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GJE18_RS06245	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GJE18_RS06250	ENOG4105VIE	preprotein translocase, subunit YajC
GJE18_RS06265	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GJE18_RS06270	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GJE18_RS06275	ENOG41090I5	UPF0735 ACT domain-containing protein
GJE18_RS06290	ENOG4105X36	(ribosomal) protein
GJE18_RS06295	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GJE18_RS06305	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GJE18_RS06320	ENOG4105W5Q	DNA repair protein (RadC
GJE18_RS06325	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GJE18_RS06330	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GJE18_RS06335	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GJE18_RS06340	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GJE18_RS06345	ENOG4108KK1	membrane protein AbrB duplication
GJE18_RS06355	ENOG4105D52	delta-aminolevulinic acid dehydratase
GJE18_RS06365	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GJE18_RS06375	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GJE18_RS06380	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GJE18_RS06390	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GJE18_RS06405	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GJE18_RS06410	ENOG4105VJV	50s ribosomal protein L35
GJE18_RS06415	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GJE18_RS06420	ENOG4108IQI	permease
GJE18_RS06425	ENOG4105C22	threonyL-tRNA synthetase
GJE18_RS06440	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GJE18_RS06445	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GJE18_RS06450	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GJE18_RS06455	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GJE18_RS06460	ENOG4105C2M	dna polymerase I
GJE18_RS06465	ENOG4105BZU	Histidine kinase
GJE18_RS06470	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GJE18_RS06475	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GJE18_RS06480	ENOG4105BZN	citrate synthase
GJE18_RS06485	ENOG4105CA9	Pyruvate kinase
GJE18_RS06490	ENOG4105CTQ	phosphohexokinase
GJE18_RS06495	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GJE18_RS06500	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GJE18_RS06505	ENOG4105C6K	Malic enzyme
GJE18_RS06510	ENOG4105C0B	DNA polymerase III (alpha subunit)
GJE18_RS06515	ENOG4105SFS	phosphoesterase RecJ domain protein
GJE18_RS06530	ENOG4105E8R	UPF0173 metal-dependent hydrolase
GJE18_RS06535	ENOG4105DC7	peptidase M24
GJE18_RS06545	ENOG4107YZX	Universal stress protein
GJE18_RS06550	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GJE18_RS06560	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GJE18_RS06565	ENOG4105VK3	rdd domain containing protein
GJE18_RS06570	ENOG4105D07	Signal peptide peptidase, SppA
GJE18_RS06575	ENOG4105EJ9	Membrane
GJE18_RS06580	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GJE18_RS06590	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
GJE18_RS06600	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GJE18_RS06605	ENOG4105CIF	Ornithine Cyclodeaminase
GJE18_RS06610	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GJE18_RS06615	ENOG4108X3M	OsmC Ohr family protein
GJE18_RS06620	ENOG4105C5R	Aminotransferase
GJE18_RS06625	ENOG4108JQ1	Dehydrogenase
GJE18_RS06635	ENOG4105F6E	Acyl-transferase
GJE18_RS06640	ENOG4105C0H	protease
GJE18_RS06645	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GJE18_RS06650	ENOG4108JQC	penicillin-binding protein 1A
GJE18_RS06655	ENOG4105CKU	formyltetrahydrofolate synthetase
GJE18_RS06665	ENOG4105F1V	Acetoin utilization protein
GJE18_RS06680	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GJE18_RS06690	ENOG4105MQN	general stress protein
GJE18_RS06695	ENOG4105DFU	Cell wall formation (By similarity)
GJE18_RS06705	ENOG4108VDD	TRNA binding domain protein
GJE18_RS06710	ENOG4108NKM	UPF0354 protein
GJE18_RS06730	ENOG4105C8F	Beta-lactamase domain protein
GJE18_RS06735	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GJE18_RS06740	ENOG4108V15	phosphotransferase enzyme family
GJE18_RS06745	ENOG4105F0I	Aminotransferase
GJE18_RS06750	ENOG4107QSE	Dipeptidase
GJE18_RS06770	ENOG4105CBX	hi0933 family
GJE18_RS06775	ENOG41085GJ	domain protein
GJE18_RS06780	ENOG4105C8T	Leucyl-tRNA synthetase
GJE18_RS06785	ENOG410605W	Major Facilitator
GJE18_RS06790	ENOG4105N5T	Radical SAM Protein
GJE18_RS06805	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GJE18_RS06810	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
GJE18_RS06825	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GJE18_RS06830	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GJE18_RS06835	ENOG4108R6K	riboflavin synthase, subunit alpha
GJE18_RS06840	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GJE18_RS06850	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
GJE18_RS06860	ENOG4106FBB	RNA Polymerase
GJE18_RS06875	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GJE18_RS06885	ENOG4105WMR	Protein CrcB homolog
GJE18_RS06890	ENOG4106A8V	Protein CrcB homolog
GJE18_RS06905	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GJE18_RS06910	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GJE18_RS06925	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GJE18_RS06945	ENOG4105VBF	alkaline shock protein
GJE18_RS06970	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
GJE18_RS06985	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
GJE18_RS07100	ENOG4105IG6	Phage terminase, large subunit
GJE18_RS07200	ENOG4105CDU	Replicative dna helicase
GJE18_RS07220	ENOG4108UUM	single-stranded DNA-binding protein
GJE18_RS07285	ENOG4105VTR	Integrase
GJE18_RS07340	ENOG4105C1Q	protoporphyrinogen oxidase
GJE18_RS07345	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GJE18_RS07350	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GJE18_RS07355	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
GJE18_RS07370	ENOG4105K59	histidine triad (HIT) protein
GJE18_RS07390	ENOG4107XMQ	Peptidyl-prolyl cis-trans isomerase
GJE18_RS07395	ENOG4105EQI	Metal Dependent Phosphohydrolase
GJE18_RS07400	ENOG4106D4I	domain protein
GJE18_RS07405	ENOG4107VRP	DNA repair exonuclease
GJE18_RS07410	ENOG4105WZB	UPF0342 protein
GJE18_RS07415	ENOG4108UH6	UPF0754 membrane protein
GJE18_RS07455	ENOG41078HS	Fibronectin binding protein B
GJE18_RS07485	ENOG4105WH1	Two component transcriptional regulator luxr family
GJE18_RS07490	ENOG4105BZU	Histidine kinase
GJE18_RS07495	ENOG4108YBP	pseudouridine synthase
GJE18_RS07500	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GJE18_RS07510	ENOG4105C9Q	fumarate hydratase class II
GJE18_RS07525	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GJE18_RS07530	ENOG4105CE4	GlcNAc 6-P deacetylase
GJE18_RS07540	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GJE18_RS07550	ENOG4105E5Q	amino acid AbC transporter
GJE18_RS07710	ENOG4105G5W	regulator Fur family
GJE18_RS07715	ENOG4105C5I	Dehydrogenase
GJE18_RS07720	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GJE18_RS07725	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GJE18_RS07730	ENOG4107NBY	Membrane
GJE18_RS07735	ENOG4105CBC	glutamate synthase
GJE18_RS07745	ENOG4105EVI	UPF0374 protein
GJE18_RS07750	ENOG4105CEN	a g-specific adenine glycosylase
GJE18_RS07755	ENOG41067AE	Membrane-bound metal-dependent hydrolase
GJE18_RS07765	ENOG4105EY8	ABC transporter
GJE18_RS07775	ENOG410902V	Modulates RecA activity (By similarity)
GJE18_RS07780	ENOG4105BZ4	penicillin-binding protein
GJE18_RS07790	ENOG4108Z0Z	intracellular protease Pfpi family
GJE18_RS07805	ENOG4108S4H	thioesterase Superfamily protein
GJE18_RS07830	ENOG4107U9T	Pfam:Ribonuclease_BN
GJE18_RS07835	ENOG4108V2W	Carbonate dehydratase
GJE18_RS07845	ENOG4105ENE	Histidine kinase
GJE18_RS07860	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GJE18_RS07870	ENOG4108V3A	UPF0421 protein
GJE18_RS07885	ENOG41090A1	ferritin
GJE18_RS07895	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GJE18_RS07915	ENOG4105CBD	Diacylglycerol kinase
GJE18_RS07920	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GJE18_RS07930	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GJE18_RS07935	ENOG4105CK7	Sodium proline symporter
GJE18_RS07945	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GJE18_RS07950	ENOG4105C4R	Atp-dependent dna helicase
GJE18_RS07960	ENOG4105KGF	protein, YerC YecD
GJE18_RS07975	ENOG4108U5N	UPF0316 protein
GJE18_RS07980	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
GJE18_RS07985	ENOG4105DAP	Nicotinate phosphoribosyltransferase
GJE18_RS07990	ENOG4107QN4	Catalyzes the production of nitric oxide (By similarity)
GJE18_RS07995	ENOG4105CQC	Prephenate dehydratase
GJE18_RS08000	ENOG4105DDI	hemolysin-type calcium-binding region
GJE18_RS08010	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GJE18_RS08020	ENOG4105C26	Dehydrogenase
GJE18_RS08025	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GJE18_RS08065	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
GJE18_RS08070	ENOG4105C6Z	Gluconate
GJE18_RS08075	ENOG4105CMG	Carbohydrate kinase
GJE18_RS08080	ENOG4105G3Z	GntR family transcriptional regulator
GJE18_RS08090	ENOG4105CJ1	ABC, transporter
GJE18_RS08110	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GJE18_RS08130	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GJE18_RS08145	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GJE18_RS08180	ENOG4105CUC	YeeE YedE family protein
GJE18_RS08190	ENOG4105C5H	ABC transporter
GJE18_RS08195	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GJE18_RS08200	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GJE18_RS08205	ENOG410801F	ribosomal-protein-alanine acetyltransferase
GJE18_RS08210	ENOG41072GX	Peptidase M22 Glycoprotease
GJE18_RS08215	ENOG4105K8N	protein family UPF0079, ATPase
GJE18_RS08220	ENOG4105C01	Dihydroxy-acid dehydratase
GJE18_RS08225	ENOG4105C7K	acetolactate synthase
GJE18_RS08235	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GJE18_RS08240	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GJE18_RS08245	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GJE18_RS08250	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GJE18_RS08260	ENOG4105C7B	Threonine dehydratase
GJE18_RS08305	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
GJE18_RS08310	ENOG4105WN5	stage II sporulation protein
GJE18_RS08315	ENOG4107SGM	protein serine threonine phosphatase
GJE18_RS08320	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
GJE18_RS08335	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GJE18_RS08340	ENOG410905X	membrane-flanked domain protein
GJE18_RS08355	ENOG4105C1J	atp-dependent rna helicase
GJE18_RS08360	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
GJE18_RS08375	ENOG4105C59	p-type ATPase
GJE18_RS08390	ENOG4105VPX	protein, conserved in bacteria
GJE18_RS08395	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GJE18_RS08405	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
GJE18_RS08410	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GJE18_RS08415	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
GJE18_RS08425	ENOG4105JH5	thiaminase II
GJE18_RS08445	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GJE18_RS08455	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GJE18_RS08475	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GJE18_RS08485	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GJE18_RS08495	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GJE18_RS08500	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
GJE18_RS08510	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GJE18_RS08515	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GJE18_RS08520	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GJE18_RS08525	ENOG4108UIC	UPF0340 protein
GJE18_RS08530	ENOG4107WAU	Protein tyrosine phosphatase
GJE18_RS08535	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GJE18_RS08540	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GJE18_RS08545	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GJE18_RS08555	ENOG41082DI	50s ribosomal protein l31
GJE18_RS08560	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GJE18_RS08565	ENOG4105C26	Dehydrogenase
GJE18_RS08575	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GJE18_RS08580	ENOG4105D2N	Aldolase
GJE18_RS08590	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GJE18_RS08615	ENOG4105HNY	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GJE18_RS08635	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GJE18_RS08650	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GJE18_RS08660	ENOG4105DFD	Na H antiporter
GJE18_RS08675	ENOG4105DG6	mannose-6-phosphate isomerase
GJE18_RS08680	ENOG4105JXH	GntR family transcriptional regulator
GJE18_RS08695	ENOG4105DKW	ABC transporter
GJE18_RS08700	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GJE18_RS08705	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GJE18_RS08720	ENOG4105CYW	agmatinase
GJE18_RS08770	ENOG4105D1F	ATP-binding protein
GJE18_RS08790	ENOG4108UT2	hemolysin iii
GJE18_RS08795	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
GJE18_RS08800	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GJE18_RS08805	ENOG4107DUR	UPF0457 protein
GJE18_RS08810	ENOG4108U1V	ABC transporter, permease
GJE18_RS08815	ENOG4105DQ5	transport system permease protein
GJE18_RS08820	ENOG4108HUF	Transporter
GJE18_RS08825	ENOG4106M28	alanine racemase domain protein
GJE18_RS08835	ENOG4107SFI	Major Facilitator superfamily
GJE18_RS08845	ENOG4105F27	Major Facilitator
GJE18_RS08850	ENOG4105C94	Transporter
GJE18_RS08855	ENOG4105CIS	alcohol dehydrogenase
GJE18_RS08860	ENOG4105CS2	ec 3.2.1.21
GJE18_RS08865	ENOG4105CK1	PTS System
GJE18_RS08870	ENOG4105VCP	PTS System
GJE18_RS08875	ENOG4105D2M	Aldolase
GJE18_RS08905	ENOG4107RIS	Acyl-transferase
GJE18_RS08910	ENOG4108HPI	phosphatidate Cytidylyltransferase
GJE18_RS08915	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
GJE18_RS08925	ENOG4105DVA	methyltransferase
GJE18_RS08930	ENOG4107TXC	Transcriptional regulator
GJE18_RS08950	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GJE18_RS08960	ENOG4108JJB	ABC transporter
GJE18_RS08970	ENOG4108ZT0	50S ribosomal protein l17
GJE18_RS08975	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GJE18_RS08980	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GJE18_RS09000	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GJE18_RS09005	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GJE18_RS09015	ENOG4105VPB	50S ribosomal protein L30
GJE18_RS09035	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GJE18_RS09040	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GJE18_RS09050	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GJE18_RS09055	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GJE18_RS09065	ENOG41082SA	50s ribosomal protein l29
GJE18_RS09075	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GJE18_RS09080	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GJE18_RS09085	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GJE18_RS09090	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GJE18_RS09095	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GJE18_RS09100	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GJE18_RS09105	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GJE18_RS09115	ENOG4105C7N	Xanthine uracil vitamin C permease
GJE18_RS09155	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
GJE18_RS09170	ENOG41065XD	Transcriptional regulator
GJE18_RS09185	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GJE18_RS09195	ENOG4108ZAF	Molybdopterin
GJE18_RS09200	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
GJE18_RS09210	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GJE18_RS09215	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
GJE18_RS09220	ENOG4105D06	uba thif-type nad fad binding protein
GJE18_RS09225	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GJE18_RS09230	ENOG4105E0C	molybdate abc transporter
GJE18_RS09235	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GJE18_RS09250	ENOG4107ZYJ	bioY protein
GJE18_RS09260	ENOG4105C6F	GntR Family Transcriptional Regulator
GJE18_RS09270	ENOG4107RJ1	sodium solute
GJE18_RS09280	ENOG4105WD1	Membrane
GJE18_RS09350	ENOG4105DFD	Na H antiporter
GJE18_RS09365	ENOG41068JE	domain protein
GJE18_RS09380	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
GJE18_RS09395	ENOG4108HIZ	formate dehydrogenase alpha subunit
GJE18_RS09400	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
GJE18_RS09430	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GJE18_RS09435	ENOG4105C5Y	PTS System
GJE18_RS09465	ENOG4107YBY	Hydrolase
GJE18_RS09480	ENOG4105C09	Bile acid
GJE18_RS09500	ENOG4105CH2	amidohydrolase
GJE18_RS09505	ENOG4105CI2	imidazolone-5-propionate hydrolase
GJE18_RS09515	ENOG4105DWD	nucleoside recognition domain protein
GJE18_RS09520	ENOG4108KB2	LysR family Transcriptional regulator
GJE18_RS09530	ENOG4106E7R	Lysostaphin resistance protein A
GJE18_RS09535	ENOG4105E66	phosphoriboisomerase A
GJE18_RS09540	ENOG4108RPX	mosc domain containing protein
GJE18_RS09550	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GJE18_RS09555	ENOG4105KK4	UPF0060 membrane protein
GJE18_RS09560	ENOG4105RHA	ABC transporter, permease
GJE18_RS09565	ENOG4108IUX	(ABC) transporter
GJE18_RS09570	ENOG4105KAF	membrAne
GJE18_RS09575	ENOG4108VX5	3-methyladenine DNA glycosylase
GJE18_RS09580	ENOG4105DFD	Na H antiporter
GJE18_RS09595	ENOG4105D6U	Sodium Glutamate Symporter
GJE18_RS09600	ENOG4105CKI	cobalamin synthesis protein
GJE18_RS09605	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
GJE18_RS09650	ENOG4105CFC	Transporter
GJE18_RS09655	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GJE18_RS09675	ENOG4105DWT	malate dehydrogenase (quinone)
GJE18_RS09705	ENOG4107QNK	)-transporter
GJE18_RS09710	ENOG4105CAY	ferredoxin--nadp reductase
GJE18_RS09735	ENOG4108U05	Transcriptional regulator
GJE18_RS09750	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GJE18_RS09755	ENOG4105DJ2	Major Facilitator Superfamily
GJE18_RS09770	ENOG4108UZ3	Transporter
GJE18_RS09775	ENOG4105CN9	Peptidase m42 family protein
GJE18_RS09790	ENOG4105DQQ	Major facilitator superfamily MFS_1
GJE18_RS09795	ENOG4105WH1	Two component transcriptional regulator luxr family
GJE18_RS09800	ENOG4105BZU	Histidine kinase
GJE18_RS09815	ENOG4105R3A	Nitrate reductase
GJE18_RS09820	ENOG4108IUE	nitrate reductase beta subunit
GJE18_RS09830	ENOG4105CGH	5'-nucleotidase
GJE18_RS09835	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GJE18_RS09840	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
GJE18_RS09845	ENOG4108IFG	nitrite reductase, (NAD(P)H)
GJE18_RS09860	ENOG4108XSB	acetyltransferase, (GNAT) family
GJE18_RS09865	ENOG4105TMB	Formate nitrite transporter
GJE18_RS09875	ENOG4107QPK	)-transporter
GJE18_RS09900	ENOG4105EJQ	L-serine dehydratase
GJE18_RS09915	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GJE18_RS09925	ENOG4108JQ7	(ABC) transporter
GJE18_RS09930	ENOG4105C3U	ABC transporter
GJE18_RS09950	ENOG4105F1A	Pyruvate formate-lyase
GJE18_RS09960	ENOG4107RDP	Dehydrogenase
GJE18_RS09965	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
GJE18_RS09970	ENOG4105BZW	Glycerate kinase
GJE18_RS09975	ENOG4108Z6X	(sortase) family
GJE18_RS09980	ENOG4105DJB	Major Facilitator Superfamily
GJE18_RS09995	ENOG4105BZG	amino acid carrier protein
GJE18_RS10000	ENOG410606W	general stress protein
GJE18_RS10005	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GJE18_RS10010	ENOG4105BZ1	(ABC) transporter
GJE18_RS10015	ENOG4105BZ1	(ABC) transporter
GJE18_RS10020	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GJE18_RS10025	ENOG4105CQB	FAD linked oxidase domain protein
GJE18_RS10030	ENOG4105DSQ	Nitric oxide reductase
GJE18_RS10045	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GJE18_RS10050	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GJE18_RS10060	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GJE18_RS10065	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GJE18_RS10070	ENOG4105DDQ	anthranilate synthase
GJE18_RS10075	ENOG4105CRQ	synthase (Component I)
GJE18_RS10080	ENOG4107RA9	decarboxylase
GJE18_RS10085	ENOG4107VHA	regulatoR
GJE18_RS10095	ENOG4105M6F	mutator MutT protein
GJE18_RS10105	ENOG4105CMR	udp-glucose 4-epimerase
GJE18_RS10110	ENOG4105D3Q	Sugar transferase
GJE18_RS10140	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GJE18_RS10180	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GJE18_RS10205	ENOG4105CH6	catalase
GJE18_RS10210	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GJE18_RS10220	ENOG4105C2C	drug resistance transporter, Bcr CflA
GJE18_RS10230	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GJE18_RS10235	ENOG4105CSR	polyphosphate kinase 2
GJE18_RS10260	ENOG4108TVJ	Nitroreductase
GJE18_RS10265	ENOG4105K56	Transcriptional regulator
GJE18_RS10275	ENOG4108IPW	abc transporter atp-binding protein
GJE18_RS10280	ENOG4105CM4	permease protein
GJE18_RS10285	ENOG4105DHS	permease protein
GJE18_RS10300	ENOG4105JHY	Membrane
GJE18_RS10320	ENOG4105CKI	cobalamin synthesis protein
GJE18_RS10325	ENOG4105DHP	deoxycytidine triphosphate deaminase
GJE18_RS10340	ENOG4105CQM	Urea amidohydrolase subunit alpha
GJE18_RS10360	ENOG4105PGM	cation diffusion facilitator family transporter
GJE18_RS10375	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GJE18_RS10380	ENOG4105FQP	Beta-lactamase
GJE18_RS10385	ENOG4107RBB	ABC transporter, permease
GJE18_RS10400	ENOG4108RCM	Nitroreductase
GJE18_RS10430	ENOG4107SJB	teichoic acid biosynthesis
GJE18_RS10455	ENOG4107RRN	ABC transporter substrate-binding protein
GJE18_RS10480	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
GJE18_RS10495	ENOG4105DM4	PTS System
GJE18_RS10515	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
GJE18_RS10525	ENOG4105C26	Dehydrogenase
GJE18_RS10530	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GJE18_RS10550	ENOG4105CMT	Dihydroxyacetone kinase
GJE18_RS10555	ENOG4105CXY	transporter
GJE18_RS10565	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GJE18_RS10570	ENOG41071FY	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
GJE18_RS10575	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GJE18_RS10585	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GJE18_RS10595	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GJE18_RS10600	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GJE18_RS10605	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GJE18_RS10610	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GJE18_RS10620	ENOG4105DBV	ornithine carbamoyltransferase
GJE18_RS10650	ENOG4105TRT	Transcriptional regulator
GJE18_RS10655	ENOG4105C94	Transporter
GJE18_RS10670	ENOG4107FQX	Alpha-acetolactate decarboxylase
GJE18_RS10675	ENOG4105G6Z	alkaline phosphatase
GJE18_RS10680	ENOG4105G6Z	alkaline phosphatase
GJE18_RS10690	ENOG4107T5V	SNARE associated Golgi
GJE18_RS10710	ENOG4105D9G	High-affinity
GJE18_RS10715	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GJE18_RS10735	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
GJE18_RS10740	ENOG4105N98	Capsule biosynthesis protein capB
GJE18_RS10750	ENOG4105PNM	synthesis protein
GJE18_RS10775	ENOG4105K7W	phage-related replication protein
GJE18_RS10800	ENOG4105CBP	Major Facilitator
GJE18_RS10825	ENOG4107PP3	Acetylornithine deacetylase
GJE18_RS10835	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GJE18_RS10845	ENOG4105CK5	oxidoreductase
GJE18_RS10850	ENOG4107RUZ	Sss sodium solute transporter superfamily
GJE18_RS10855	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
GJE18_RS10860	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
GJE18_RS10865	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
GJE18_RS10870	ENOG4105D7K	pfkb domain protein
GJE18_RS10880	ENOG4105C26	Dehydrogenase
GJE18_RS10915	ENOG4105CXY	transporter
GJE18_RS10925	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
GJE18_RS10930	ENOG4105D3W	isochorismatase
GJE18_RS10935	ENOG4105C2C	drug resistance transporter, Bcr CflA
GJE18_RS10990	ENOG4105WYW	fructose-bisphosphate aldolase
GJE18_RS11005	ENOG4105D94	Major Facilitator Superfamily
GJE18_RS11035	ENOG4105D9N	nucleoside
GJE18_RS11040	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
GJE18_RS11050	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
GJE18_RS11055	ENOG4105ETD	TRANSCRIPTIONal
GJE18_RS11070	ENOG4105ENY	Ethanolamine utilization protein eutH
GJE18_RS11075	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GJE18_RS11085	ENOG4105C26	Dehydrogenase
GJE18_RS11095	ENOG4105DWD	nucleoside recognition domain protein
GJE18_RS11100	ENOG4107SUZ	Sodium/hydrogen exchanger family
GJE18_RS11110	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GJE18_RS11115	ENOG4105CNN	ABC, transporter
GJE18_RS11120	ENOG4105C2J	ABC transporter
GJE18_RS11125	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GJE18_RS11130	ENOG4108RVA	ribokinase
GJE18_RS11135	ENOG4105ETE	Transcriptional regulator (LacI family
GJE18_RS11140	ENOG4105C5X	domain protein
GJE18_RS11145	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
GJE18_RS11150	ENOG4105XTG	Pfam:DUF156
GJE18_RS11155	ENOG41087NI	Sulfite exporter TauE/SafE
GJE18_RS11160	ENOG4107QN2	dihydrolipoyl dehydrogenase
GJE18_RS11175	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GJE18_RS11185	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
GJE18_RS11190	ENOG4105CEY	Amp-dependent synthetase and ligase
GJE18_RS11195	ENOG4105C1G	acyl-Coa dehydrogenase
GJE18_RS11205	ENOG4105CHU	acetyl-coa acetyltransferase
GJE18_RS11210	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GJE18_RS11220	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
GJE18_RS11235	ENOG41089G2	accessory Sec system protein Asp2
GJE18_RS11240	ENOG4108XJK	accessory Sec system protein Asp1
GJE18_RS11245	ENOG4106YAG	Part of the accessory SecA2 SecY2 system specifically required for export of
GJE18_RS11255	ENOG4105DAA	L-lactate
GJE18_RS11265	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GJE18_RS11270	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GJE18_RS11275	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GJE18_RS11305	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GJE18_RS11340	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GJE18_RS11345	ENOG4105DBV	ornithine carbamoyltransferase
GJE18_RS11375	ENOG4105CJZ	response regulator
GJE18_RS11380	ENOG4105BZU	Histidine kinase
GJE18_RS11395	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GJE18_RS11415	ENOG4105C85	amino acid
GJE18_RS11420	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
GJE18_RS11425	ENOG4105DWT	malate dehydrogenase (quinone)
GJE18_RS11435	ENOG4105F27	Major Facilitator
GJE18_RS11440	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GJE18_RS11450	ENOG4105DBV	ornithine carbamoyltransferase
GJE18_RS11465	ENOG4105IJS	Transcriptional regulator
GJE18_RS11475	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
GJE18_RS11485	ENOG4105R40	Glycine betaine carnitine choline
GJE18_RS11495	ENOG4105E90	ABC transporter
GJE18_RS11510	ENOG4105CSH	Transporter
GJE18_RS11540	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GJE18_RS11550	ENOG4105CGD	Nad-dependent epimerase dehydratase
GJE18_RS11565	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GJE18_RS11595	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GJE18_RS11600	ENOG4108J8C	transporter major facilitator family protein
GJE18_RS11605	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GJE18_RS11610	ENOG4105FDP	GntR family transcriptional regulator
GJE18_RS11630	ENOG4108YM7	Gcn5-related n-acetyltransferase
GJE18_RS11635	ENOG4108S3Y	transcriptional regulator
GJE18_RS11640	ENOG4105CS2	ec 3.2.1.21
GJE18_RS11645	ENOG4105VMP	Transcriptional regulator
GJE18_RS11685	ENOG4108MES	Periplasmic binding protein
GJE18_RS11690	ENOG4105DQ5	transport system permease protein
GJE18_RS11695	ENOG4108IHU	transport system permease protein
GJE18_RS11700	ENOG4105DSE	periplasmic solute binding protein
GJE18_RS11710	ENOG4105CCI	Myosin-Cross-Reactive Antigen
GJE18_RS11725	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
GJE18_RS11740	ENOG4106QP9	(LipO)protein
GJE18_RS11745	ENOG4106QP9	(LipO)protein
GJE18_RS11755	ENOG41067QW	Transcriptional regulator
GJE18_RS11790	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
GJE18_RS11815	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GJE18_RS11820	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GJE18_RS11825	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GJE18_RS11835	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
GJE18_RS11855	ENOG4105C57	major facilitator superfamily
GJE18_RS11870	ENOG4105CHR	reductase
GJE18_RS11875	ENOG41067FT	ParB-like nuclease domain
GJE18_RS11880	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GJE18_RS11885	ENOG4105CNV	Aldolase
GJE18_RS11890	ENOG4105DUU	IucA IucC family protein
GJE18_RS11895	ENOG4105DBM	Siderophore biosynthesis protein
GJE18_RS11900	ENOG4105C6X	Major Facilitator
GJE18_RS11905	ENOG4105DJU	Siderophore biosynthesis protein
GJE18_RS11910	ENOG4105CIF	Ornithine Cyclodeaminase
GJE18_RS11935	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GJE18_RS11940	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GJE18_RS11945	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
GJE18_RS11970	ENOG4106KKU	
GJE18_RS11975	ENOG4108Z15	abc transporter atp-binding protein
GJE18_RS12005	ENOG4108UXE	Protein tyrosine phosphatase
GJE18_RS12010	ENOG4107R5R	arsenical pump membrane protein
GJE18_RS12020	ENOG4105Q2H	domain protein
GJE18_RS12035	ENOG4105BZU	Histidine kinase
GJE18_RS12060	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GJE18_RS12065	ENOG4105CDU	Replicative dna helicase
GJE18_RS12070	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GJE18_RS12075	ENOG4105BZR	domain protein
GJE18_RS12080	ENOG4108XMW	Membrane
GJE18_RS12085	ENOG4105DWV	Homoserine O-trans-acetylase
GJE18_RS12095	ENOG4108UMN	azlc family