locus-tag	class	description
HZR12_RS00015	COG2501	S4 domain
HZR12_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HZR12_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HZR12_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HZR12_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
HZR12_RS00110	COG4863	YycH protein
HZR12_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HZR12_RS00150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZR12_RS00150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZR12_RS00195	COG0584	glycerophosphoryl diester phosphodiesterase
HZR12_RS00200	COG2030	dehydratase
HZR12_RS00250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HZR12_RS00290	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HZR12_RS00295	COG1353	crispr-associated protein
HZR12_RS00300	COG1421	Csm2 Type III-A
HZR12_RS00305	COG1337	RAMP superfamily
HZR12_RS00310	COG1567	CRISPR-associated RAMP protein, Csm4 family
HZR12_RS00315	COG1332	CRISPR-associated RAMP protein, Csm5 family
HZR12_RS00340	COG1002	Type II restriction enzyme, methylase subunits
HZR12_RS00350	COG2801	Transposase and inactivated derivatives
HZR12_RS00355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HZR12_RS00365	COG0745	RESPONSE REGULATOR receiver
HZR12_RS00370	COG2205	protein histidine kinase activity
HZR12_RS00380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HZR12_RS00385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HZR12_RS00390	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HZR12_RS00415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HZR12_RS00445	COG0640	Transcriptional regulator
HZR12_RS00460	COG1064	alcohol dehydrogenase
HZR12_RS00520	COG0655	NAD(P)H dehydrogenase (quinone) activity
HZR12_RS00535	COG1073	alpha beta
HZR12_RS00555	COG0823	Involved in the tonB-independent uptake of proteins
HZR12_RS00580	COG1473	amidohydrolase
HZR12_RS00590	COG1283	sodium-dependent phosphate transmembrane transporter activity
HZR12_RS00595	COG4716	Myosin-crossreactive antigen
HZR12_RS00615	COG1620	l-lactate permease
HZR12_RS00630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZR12_RS00635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZR12_RS00640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZR12_RS00650	COG2423	ornithine cyclodeaminase activity
HZR12_RS00655	COG4264	IucA IucC family
HZR12_RS00660	COG2814	Major facilitator Superfamily
HZR12_RS00665	COG4264	IucA IucC family
HZR12_RS00670	COG4264	IucA IucC family
HZR12_RS00680	COG0019	diaminopimelate decarboxylase activity
HZR12_RS00685	COG1475	DNA binding
HZR12_RS00705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZR12_RS00715	COG0438	transferase activity, transferring glycosyl groups
HZR12_RS00750	COG2814	Major facilitator Superfamily
HZR12_RS00770	COG3639	organic phosphonate transmembrane transporter activity
HZR12_RS00790	COG0737	Belongs to the 5'-nucleotidase family
HZR12_RS00815	COG1012	belongs to the aldehyde dehydrogenase family
HZR12_RS00815	COG1454	alcohol dehydrogenase
HZR12_RS00840	COG1086	Polysaccharide biosynthesis protein
HZR12_RS00850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HZR12_RS00880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HZR12_RS00890	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HZR12_RS00895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HZR12_RS00905	COG2832	Protein of unknown function (DUF454)
HZR12_RS00940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZR12_RS00945	COG1960	acyl-CoA dehydrogenase activity
HZR12_RS00950	COG5609	conserved protein (DUF2294)
HZR12_RS00990	COG2801	Transposase and inactivated derivatives
HZR12_RS01000	COG1785	Belongs to the alkaline phosphatase family
HZR12_RS01010	COG0745	RESPONSE REGULATOR receiver
HZR12_RS01015	COG2205	protein histidine kinase activity
HZR12_RS01020	COG1136	(ABC) transporter
HZR12_RS01040	COG0386	Belongs to the glutathione peroxidase family
HZR12_RS01050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HZR12_RS01065	COG2851	Citrate transporter
HZR12_RS01090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HZR12_RS01100	COG1510	regulation of RNA biosynthetic process
HZR12_RS01110	COG1012	belongs to the aldehyde dehydrogenase family
HZR12_RS01130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HZR12_RS01160	COG0531	amino acid
HZR12_RS01170	COG3527	Alpha-acetolactate decarboxylase
HZR12_RS01175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HZR12_RS01185	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HZR12_RS01225	COG0167	dihydroorotate dehydrogenase activity
HZR12_RS01230	COG3001	Fructosamine kinase
HZR12_RS01265	COG0596	Alpha beta hydrolase
HZR12_RS01330	COG2801	Transposase and inactivated derivatives
HZR12_RS01345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HZR12_RS01345	COG2755	lipolytic protein G-D-S-L family
HZR12_RS01350	COG3942	CHAP domain
HZR12_RS01380	COG0436	Aminotransferase
HZR12_RS01425	COG2409	Drug exporters of the RND superfamily
HZR12_RS01445	COG0542	response to heat
HZR12_RS01450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HZR12_RS01455	COG3425	synthase
HZR12_RS01480	COG3942	CHAP domain
HZR12_RS01490	COG0583	DNA-binding transcription factor activity
HZR12_RS01505	COG0028	Belongs to the TPP enzyme family
HZR12_RS01525	COG0657	acetylesterase activity
HZR12_RS01530	COG0697	spore germination
HZR12_RS01545	COG1760	l-serine dehydratase
HZR12_RS01550	COG1760	l-serine dehydratase
HZR12_RS01570	COG3764	Sortase (surface protein transpeptidase)
HZR12_RS01580	COG1131	(ABC) transporter
HZR12_RS01585	COG0561	phosphatase activity
HZR12_RS01600	COG2514	catechol 2,3-dioxygenase activity
HZR12_RS01610	COG1846	Transcriptional regulator
HZR12_RS01615	COG0346	lactoylglutathione lyase activity
HZR12_RS01620	COG0400	carboxylic ester hydrolase activity
HZR12_RS01625	COG3949	Membrane
HZR12_RS01640	COG1131	(ABC) transporter
HZR12_RS01645	COG1846	Transcriptional regulator
HZR12_RS01650	COG2814	Major facilitator Superfamily
HZR12_RS01660	COG0586	Pfam SNARE associated Golgi protein
HZR12_RS01665	COG2271	Major facilitator Superfamily
HZR12_RS01675	COG4876	unkown
HZR12_RS01680	COG2357	RelA SpoT domain protein
HZR12_RS01685	COG0789	Transcriptional regulator
HZR12_RS01690	COG1802	Transcriptional regulator
HZR12_RS01695	COG1070	Carbohydrate kinase
HZR12_RS01710	COG4932	domain protein
HZR12_RS01720	COG2801	Transposase and inactivated derivatives
HZR12_RS01735	COG1846	Transcriptional regulator
HZR12_RS01740	COG1846	Transcriptional regulator
HZR12_RS01775	COG0494	nUDIX hydrolase
HZR12_RS01860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HZR12_RS01865	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HZR12_RS01895	COG0747	negative chemotaxis
HZR12_RS01900	COG0601	transmembrane transport
HZR12_RS01905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZR12_RS01910	COG0444	Belongs to the ABC transporter superfamily
HZR12_RS01915	COG1124	(ABC) transporter
HZR12_RS01930	COG0069	glutamate synthase activity
HZR12_RS01935	COG4808	Protein conserved in bacteria
HZR12_RS01950	COG1363	Peptidase, m42
HZR12_RS01955	COG4619	ABC transporter
HZR12_RS01960	COG0390	transport system, permease component
HZR12_RS01965	COG2814	Major facilitator Superfamily
HZR12_RS01970	COG2272	Belongs to the type-B carboxylesterase lipase family
HZR12_RS01975	COG0531	amino acid
HZR12_RS01980	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
HZR12_RS02000	COG1174	glycine betaine transport
HZR12_RS02010	COG1174	glycine betaine transport
HZR12_RS02020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HZR12_RS02030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HZR12_RS02035	COG0531	amino acid
HZR12_RS02045	COG1113	amino acid transport
HZR12_RS02065	COG2814	Major facilitator Superfamily
HZR12_RS02075	COG1929	Belongs to the glycerate kinase type-1 family
HZR12_RS02095	COG1132	(ABC) transporter
HZR12_RS02105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HZR12_RS02110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HZR12_RS02120	COG0156	8-amino-7-oxononanoate synthase activity
HZR12_RS02160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HZR12_RS02175	COG2814	Major facilitator Superfamily
HZR12_RS02180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZR12_RS02185	COG0765	amino acid transport
HZR12_RS02190	COG1126	abc transporter atp-binding protein
HZR12_RS02250	COG3443	Belongs to the bacterial solute-binding protein 9 family
HZR12_RS02250	COG0803	Belongs to the bacterial solute-binding protein 9 family
HZR12_RS02265	COG2116	formate transmembrane transporter activity
HZR12_RS02270	COG0454	-acetyltransferase
HZR12_RS02280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HZR12_RS02285	COG2146	nitrite reductase [NAD(P)H] activity
HZR12_RS02295	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HZR12_RS02300	COG1140	nitrate reductase beta subunit
HZR12_RS02310	COG2181	nitrate reductase activity
HZR12_RS02330	COG0789	Transcriptional regulator
HZR12_RS02370	COG3871	stress protein (general stress protein 26)
HZR12_RS02385	COG1263	PTS System
HZR12_RS02385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZR12_RS02400	COG1511	domain protein
HZR12_RS02420	COG0456	acetyltransferase
HZR12_RS02425	COG0604	alcohol dehydrogenase
HZR12_RS02445	COG1620	l-lactate permease
HZR12_RS02510	COG2814	Major facilitator Superfamily
HZR12_RS02520	COG1566	PFAM secretion protein HlyD family protein
HZR12_RS02525	COG2814	Major facilitator Superfamily
HZR12_RS02535	COG0657	acetylesterase activity
HZR12_RS02550	COG0598	Magnesium transport protein CorA
HZR12_RS02560	COG0786	glutamate:sodium symporter activity
HZR12_RS02575	COG4152	abc transporter atp-binding protein
HZR12_RS02580	COG1668	transmembrane transport
HZR12_RS02600	COG2258	MOSC domain
HZR12_RS02640	COG1473	amidohydrolase
HZR12_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
HZR12_RS02665	COG1737	Transcriptional regulator
HZR12_RS02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZR12_RS02670	COG1263	PTS System
HZR12_RS02680	COG0385	Bile acid
HZR12_RS02685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZR12_RS02705	COG1113	amino acid transport
HZR12_RS02775	COG3942	CHAP domain
HZR12_RS02790	COG1757	Na H antiporter
HZR12_RS02800	COG3942	CHAP domain
HZR12_RS02860	COG4413	Urea transporter
HZR12_RS02865	COG1960	acyl-CoA dehydrogenase activity
HZR12_RS02880	COG1268	BioY protein
HZR12_RS02895	COG0725	ABC transporter, periplasmic molybdate-binding protein
HZR12_RS02900	COG4149	molybdate abc transporter
HZR12_RS02905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HZR12_RS02910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HZR12_RS02930	COG1763	Mo-molybdopterin cofactor biosynthetic process
HZR12_RS02990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HZR12_RS03035	COG2252	PERMEase
HZR12_RS03150	COG0201	protein transport
HZR12_RS03235	COG0542	response to heat
HZR12_RS03255	COG0028	Belongs to the TPP enzyme family
HZR12_RS03260	COG3527	Alpha-acetolactate decarboxylase
HZR12_RS03280	COG5492	domain, Protein
HZR12_RS03295	COG0656	L-ascorbic acid biosynthetic process
HZR12_RS03315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HZR12_RS03365	COG2130	NADP-dependent
HZR12_RS03375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HZR12_RS03405	COG2814	Major facilitator Superfamily
HZR12_RS03410	COG4264	IucA IucC family
HZR12_RS03415	COG3457	Alanine racemase
HZR12_RS03425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HZR12_RS03430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZR12_RS03435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZR12_RS03450	COG1988	membrane-bound metal-dependent
HZR12_RS03460	COG1272	protein, Hemolysin III
HZR12_RS03475	COG2814	Major facilitator Superfamily
HZR12_RS03480	COG0489	protein tyrosine kinase activity
HZR12_RS03555	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HZR12_RS03575	COG0246	Mannitol dehydrogenase
HZR12_RS03585	COG3711	transcriptional antiterminator
HZR12_RS03600	COG1119	ATPase activity
HZR12_RS03605	COG0561	phosphatase activity
HZR12_RS03640	COG0640	Transcriptional regulator
HZR12_RS03645	COG0702	epimerase
HZR12_RS03650	COG1482	cell wall glycoprotein biosynthetic process
HZR12_RS03670	COG0783	Belongs to the Dps family
HZR12_RS03675	COG0813	purine-nucleoside phosphorylase activity
HZR12_RS03720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZR12_RS03730	COG0504	CTP synthase activity
HZR12_RS03760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HZR12_RS03780	COG2890	protein-(glutamine-N5) methyltransferase activity
HZR12_RS03785	COG0009	L-threonylcarbamoyladenylate synthase
HZR12_RS03810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HZR12_RS03885	COG0629	single-stranded DNA binding
HZR12_RS03920	COG1418	mRNA catabolic process
HZR12_RS03930	COG1937	Protein conserved in bacteria
HZR12_RS03945	COG0772	Belongs to the SEDS family
HZR12_RS03955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HZR12_RS03965	COG2801	Transposase and inactivated derivatives
HZR12_RS03975	COG0745	RESPONSE REGULATOR receiver
HZR12_RS03980	COG2205	protein histidine kinase activity
HZR12_RS04010	COG3428	Bacterial PH domain
HZR12_RS04040	COG2208	phosphoserine phosphatase activity
HZR12_RS04045	COG1366	Belongs to the anti-sigma-factor antagonist family
HZR12_RS04055	COG1191	sigma factor activity
HZR12_RS04060	COG2183	response to ionizing radiation
HZR12_RS04110	COG0473	3-isopropylmalate dehydrogenase activity
HZR12_RS04130	COG0028	Belongs to the TPP enzyme family
HZR12_RS04145	COG0802	atpase or kinase
HZR12_RS04150	COG1214	PFAM Peptidase M22, glycoprotease
HZR12_RS04155	COG0456	acetyltransferase
HZR12_RS04165	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HZR12_RS04175	COG0488	(ABC) transporter
HZR12_RS04185	COG2391	methyltransferase activity
HZR12_RS04190	COG0425	Belongs to the sulfur carrier protein TusA family
HZR12_RS04195	COG0004	ammonium transporteR
HZR12_RS04200	COG1609	Transcriptional regulator
HZR12_RS04205	COG1621	beta-fructofuranosidase activity
HZR12_RS04210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZR12_RS04245	COG2801	Transposase and inactivated derivatives
HZR12_RS04285	COG0582	viral genome integration into host DNA
HZR12_RS04290	COG1396	sequence-specific DNA binding
HZR12_RS04365	COG3728	DNA packaging
HZR12_RS04365	COG5484	DNA packaging
HZR12_RS04385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZR12_RS04390	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HZR12_RS04395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HZR12_RS04400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZR12_RS04410	COG2801	Transposase and inactivated derivatives
HZR12_RS04465	COG1725	Transcriptional regulator
HZR12_RS04480	COG1131	(ABC) transporter
HZR12_RS04535	COG1012	belongs to the aldehyde dehydrogenase family
HZR12_RS04550	COG1335	isochorismatase
HZR12_RS04560	COG0471	metal ion transport
HZR12_RS04570	COG0077	Prephenate dehydratase
HZR12_RS04580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HZR12_RS04615	COG4496	protein, YerC YecD
HZR12_RS04625	COG0210	DNA helicase
HZR12_RS04745	COG2197	response regulator
HZR12_RS04750	COG1295	ribonuclease BN
HZR12_RS04770	COG2309	aminopeptidase activity
HZR12_RS04775	COG1607	acyl-coa hydrolase
HZR12_RS04780	COG0535	radical SAM domain protein
HZR12_RS04810	COG1388	LysM domain
HZR12_RS04810	COG1134	teichoic acid transport
HZR12_RS04820	COG1988	membrane-bound metal-dependent
HZR12_RS04845	COG4129	membrane
HZR12_RS04855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HZR12_RS04860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HZR12_RS05035	COG0765	amino acid transport
HZR12_RS05040	COG1126	abc transporter atp-binding protein
HZR12_RS05045	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HZR12_RS05075	COG0564	pseudouridine synthase activity
HZR12_RS05080	COG4585	Histidine kinase
HZR12_RS05080	COG2203	Gaf domain
HZR12_RS05085	COG2197	response regulator
HZR12_RS05110	COG0420	3'-5' exonuclease activity
HZR12_RS05140	COG0537	adenosine 5'-monophosphoramidase activity
HZR12_RS05145	COG1131	(ABC) transporter
HZR12_RS05245	COG2801	Transposase and inactivated derivatives
HZR12_RS05310	COG2801	Transposase and inactivated derivatives
HZR12_RS05330	COG3682	Transcriptional regulator
HZR12_RS05370	COG2855	membrane
HZR12_RS05375	COG0583	DNA-binding transcription factor activity
HZR12_RS05385	COG2801	Transposase and inactivated derivatives
HZR12_RS05510	COG0656	L-ascorbic acid biosynthetic process
HZR12_RS05535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HZR12_RS05555	COG1595	DNA-templated transcription, initiation
HZR12_RS05565	COG3266	domain, Protein
HZR12_RS05565	COG4193	domain, Protein
HZR12_RS05565	COG5632	N-Acetylmuramoyl-L-alanine amidase
HZR12_RS05590	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HZR12_RS05590	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HZR12_RS05620	COG2267	carboxylic ester hydrolase activity
HZR12_RS05635	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HZR12_RS05640	COG1242	4 iron, 4 sulfur cluster binding
HZR12_RS05645	COG2814	Major facilitator Superfamily
HZR12_RS05665	COG2081	HI0933 family
HZR12_RS05670	COG2244	polysaccharide biosynthetic process
HZR12_RS05675	COG1187	pseudouridine synthase activity
HZR12_RS05695	COG0510	thiamine kinase activity
HZR12_RS05705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZR12_RS05715	COG1363	Peptidase, m42
HZR12_RS05720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZR12_RS05730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZR12_RS05735	COG1674	ftsk spoiiie
HZR12_RS05760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HZR12_RS05760	COG1605	Chorismate mutase
HZR12_RS05780	COG0454	-acetyltransferase
HZR12_RS05785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HZR12_RS05790	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HZR12_RS05800	COG5386	Cell surface protein
HZR12_RS05820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZR12_RS05825	COG0204	Acyl-transferase
HZR12_RS05830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZR12_RS05830	COG1263	PTS System
HZR12_RS05845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HZR12_RS05850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HZR12_RS05855	COG1764	response to oxidative stress
HZR12_RS05860	COG0584	glycerophosphoryl diester phosphodiesterase
HZR12_RS05870	COG1956	GAF domain-containing protein
HZR12_RS05885	COG1104	cysteine desulfurase activity
HZR12_RS05905	COG0827	DNA restriction-modification system
HZR12_RS05945	COG4109	DRTGG domain
HZR12_RS05950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HZR12_RS05955	COG0587	DNA-directed DNA polymerase activity
HZR12_RS05960	COG0281	malic enzyme
HZR12_RS05990	COG1113	amino acid transport
HZR12_RS05995	COG0372	Belongs to the citrate synthase family
HZR12_RS06005	COG0745	RESPONSE REGULATOR receiver
HZR12_RS06010	COG5002	protein histidine kinase activity
HZR12_RS06020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZR12_RS06020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZR12_RS06050	COG1484	DNA-dependent DNA replication
HZR12_RS06060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HZR12_RS06065	COG0833	amino acid
HZR12_RS06085	COG4112	unkown
HZR12_RS06115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HZR12_RS06120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HZR12_RS06155	COG2818	Glycosylase
HZR12_RS06165	COG0285	dihydrofolate synthase activity
HZR12_RS06170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HZR12_RS06215	COG2868	ribosomal protein
HZR12_RS06255	COG1862	Preprotein translocase
HZR12_RS06260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HZR12_RS06260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HZR12_RS06265	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HZR12_RS06265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HZR12_RS06295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HZR12_RS06310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HZR12_RS06315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HZR12_RS06320	COG1959	2 iron, 2 sulfur cluster binding
HZR12_RS06325	COG3237	CsbD-like
HZR12_RS06335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZR12_RS06340	COG1104	cysteine desulfurase activity
HZR12_RS06355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HZR12_RS06405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HZR12_RS06410	COG1984	allophanate hydrolase subunit 2
HZR12_RS06415	COG0511	ligase activity, forming carbon-carbon bonds
HZR12_RS06420	COG0439	Biotin carboxylase
HZR12_RS06430	COG1914	H( )-stimulated, divalent metal cation uptake system
HZR12_RS06435	COG3177	Filamentation induced by cAMP protein fic
HZR12_RS06455	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HZR12_RS06460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HZR12_RS06470	COG1534	Rna-binding protein
HZR12_RS06480	COG1713	HD superfamily hydrolase involved in NAD metabolism
HZR12_RS06485	COG0799	negative regulation of ribosome biogenesis
HZR12_RS06490	COG2226	methyltransferase
HZR12_RS06500	COG2131	deaminase
HZR12_RS06505	COG2333	competence protein COMEC
HZR12_RS06505	COG0658	competence protein
HZR12_RS06510	COG1466	dna polymerase III delta subunit
HZR12_RS06525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HZR12_RS06555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HZR12_RS06560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZR12_RS06570	COG1030	water channel activity
HZR12_RS06585	COG1702	phosphate starvation-inducible protein PhoH
HZR12_RS06600	COG0295	cytidine deaminase activity
HZR12_RS06605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HZR12_RS06620	COG0517	IMP dehydrogenase activity
HZR12_RS06640	COG2384	SAM-dependent methyltransferase
HZR12_RS06650	COG0513	Belongs to the DEAD box helicase family
HZR12_RS06660	COG1121	(ABC) transporter
HZR12_RS06665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HZR12_RS06690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HZR12_RS06700	COG4483	Protein conserved in bacteria
HZR12_RS06705	COG1940	carbohydrate kinase activity
HZR12_RS06710	COG0011	TIGRFAM Protein of
HZR12_RS06715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZR12_RS06720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HZR12_RS06730	COG4537	Required for transformation and DNA binding
HZR12_RS06775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HZR12_RS06780	COG0095	Lipoate-protein ligase
HZR12_RS06795	COG0006	proline dipeptidase activity
HZR12_RS06805	COG0511	ligase activity, forming carbon-carbon bonds
HZR12_RS06810	COG0439	Biotin carboxylase
HZR12_RS06815	COG1302	Protein conserved in bacteria
HZR12_RS06845	COG0497	DNA recombination
HZR12_RS06850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZR12_RS06855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HZR12_RS06860	COG0022	dehydrogenase e1 component
HZR12_RS06865	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZR12_RS06875	COG4129	membrane
HZR12_RS06885	COG2195	Cleaves the N-terminal amino acid of tripeptides
HZR12_RS06905	COG1609	Transcriptional regulator
HZR12_RS06910	COG0366	Alpha amylase catalytic
HZR12_RS06920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HZR12_RS06935	COG4221	oxidoreductase activity
HZR12_RS06945	COG0667	Aldo Keto reductase
HZR12_RS06950	COG0494	nUDIX hydrolase
HZR12_RS06955	COG0735	belongs to the Fur family
HZR12_RS06980	COG1187	pseudouridine synthase activity
HZR12_RS06985	COG0745	RESPONSE REGULATOR receiver
HZR12_RS06990	COG5002	protein histidine kinase activity
HZR12_RS07035	COG1141	Ferredoxin
HZR12_RS07045	COG0514	ATP-dependent DNA helicase (RecQ)
HZR12_RS07060	COG0492	ferredoxin-NADP+ reductase activity
HZR12_RS07115	COG0142	geranyltranstransferase activity
HZR12_RS07135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HZR12_RS07150	COG5582	Belongs to the UPF0302 family
HZR12_RS07155	COG4347	Protein of unknown function (DUF1405)
HZR12_RS07160	COG2738	Putative neutral zinc metallopeptidase
HZR12_RS07165	COG1694	Mazg nucleotide pyrophosphohydrolase
HZR12_RS07170	COG0438	transferase activity, transferring glycosyl groups
HZR12_RS07195	COG3935	DnaD domain protein
HZR12_RS07200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HZR12_RS07210	COG4499	WXG100 protein secretion system (Wss), protein YukC
HZR12_RS07210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HZR12_RS07245	COG0116	Belongs to the methyltransferase superfamily
HZR12_RS07260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HZR12_RS07265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZR12_RS07270	COG0686	Belongs to the AlaDH PNT family
HZR12_RS07280	COG0531	amino acid
HZR12_RS07300	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HZR12_RS07315	COG1413	lyase activity
HZR12_RS07370	COG2801	Transposase and inactivated derivatives
HZR12_RS07385	COG0671	phosphoesterase, PA-phosphatase related
HZR12_RS07430	COG0714	Associated with various cellular activities
HZR12_RS07435	COG4548	von Willebrand factor, type A
HZR12_RS07510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HZR12_RS07515	COG0527	aspartate kinase activity
HZR12_RS07520	COG0488	(ABC) transporter
HZR12_RS07540	COG0573	inorganic phosphate transmembrane transporter activity
HZR12_RS07545	COG0581	inorganic phosphate transmembrane transporter activity
HZR12_RS07555	COG0704	Plays a role in the regulation of phosphate uptake
HZR12_RS07600	COG0561	phosphatase activity
HZR12_RS07640	COG0512	Glutamine amidotransferase of anthranilate synthase
HZR12_RS07645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HZR12_RS07650	COG1363	Peptidase, m42
HZR12_RS07660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HZR12_RS07680	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HZR12_RS07680	COG0392	lysyltransferase activity
HZR12_RS07685	COG0628	permease
HZR12_RS07700	COG1115	amino acid carrier protein
HZR12_RS07705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HZR12_RS07725	COG0824	Thioesterase
HZR12_RS07735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HZR12_RS07755	COG4846	Membrane protein involved in cytochrome C biogenesis
HZR12_RS07790	COG2340	Cysteine-rich secretory protein family
HZR12_RS07815	COG0833	amino acid
HZR12_RS07840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HZR12_RS07845	COG0460	homoserine dehydrogenase
HZR12_RS07850	COG0527	aspartate kinase activity
HZR12_RS07865	COG1525	nuclease
HZR12_RS07875	COG2197	response regulator
HZR12_RS07890	COG1131	(ABC) transporter
HZR12_RS07980	COG2801	Transposase and inactivated derivatives
HZR12_RS08005	COG0789	Transcriptional regulator
HZR12_RS08010	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HZR12_RS08025	COG1923	regulation of RNA biosynthetic process
HZR12_RS08050	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HZR12_RS08055	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HZR12_RS08090	COG1013	pyruvate-flavodoxin oxidoreductase activity
HZR12_RS08095	COG0674	pyruvate-flavodoxin oxidoreductase activity
HZR12_RS08095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HZR12_RS08100	COG1692	metallophosphoesterase
HZR12_RS08120	COG1546	Belongs to the CinA family
HZR12_RS08120	COG1058	Belongs to the CinA family
HZR12_RS08140	COG0300	oxidoreductase activity
HZR12_RS08145	COG0612	Peptidase, M16
HZR12_RS08150	COG0612	Peptidase, M16
HZR12_RS08155	COG2188	Transcriptional regulator
HZR12_RS08180	COG0196	riboflavin kinase activity
HZR12_RS08200	COG1358	cellular component organization or biogenesis
HZR12_RS08205	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HZR12_RS08210	COG0195	Participates in both transcription termination and antitermination
HZR12_RS08305	COG0758	DNA mediated transformation
HZR12_RS08365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HZR12_RS08375	COG0552	protein localization to endoplasmic reticulum
HZR12_RS08380	COG1196	nuclear chromosome segregation
HZR12_RS08415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HZR12_RS08425	COG2801	Transposase and inactivated derivatives
HZR12_RS08435	COG1302	Protein conserved in bacteria
HZR12_RS08450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HZR12_RS08465	COG0631	protein serine/threonine phosphatase activity
HZR12_RS08475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HZR12_RS08475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HZR12_RS08490	COG2314	TM2 domain
HZR12_RS08500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HZR12_RS08505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HZR12_RS08520	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HZR12_RS08565	COG2233	PERMEase
HZR12_RS08575	COG0564	pseudouridine synthase activity
HZR12_RS08590	COG2514	catechol 2,3-dioxygenase activity
HZR12_RS08600	COG3599	regulation of cell shape
HZR12_RS08605	COG2302	S4 RNA-binding domain
HZR12_RS08610	COG0762	integral membrane protein
HZR12_RS08620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HZR12_RS08635	COG0849	cell division
HZR12_RS08640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HZR12_RS08660	COG4839	cell division protein FtsL
HZR12_RS08685	COG1011	Hydrolase
HZR12_RS08720	COG1288	antiporter activity
HZR12_RS08825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HZR12_RS08830	COG1053	succinate dehydrogenase
HZR12_RS08835	COG2009	succinate dehydrogenase
HZR12_RS08860	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HZR12_RS08860	COG1796	DNA polymerase
HZR12_RS08890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HZR12_RS08905	COG4509	Sortase family
HZR12_RS08960	COG0742	ribosomal rna small subunit methyltransferase
HZR12_RS08980	COG3679	Belongs to the UPF0342 family
HZR12_RS09010	COG0772	Belongs to the SEDS family
HZR12_RS09020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HZR12_RS09040	COG0483	inositol monophosphate 1-phosphatase activity
HZR12_RS09065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HZR12_RS09070	COG1177	transmembrane transport
HZR12_RS09075	COG1176	ABC-type spermidine putrescine transport system, permease component I
HZR12_RS09140	COG0569	domain protein
HZR12_RS09145	COG1294	oxidase, subunit
HZR12_RS09150	COG1271	oxidase subunit
HZR12_RS09175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HZR12_RS09190	COG4721	ABC-type cobalt transport system, permease component
HZR12_RS09195	COG4172	Belongs to the ABC transporter superfamily
HZR12_RS09200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HZR12_RS09210	COG0138	bifunctional purine biosynthesis protein purh
HZR12_RS09240	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HZR12_RS09255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HZR12_RS09295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HZR12_RS09300	COG1316	TRANSCRIPTIONal
HZR12_RS09330	COG3594	Acyltransferase
HZR12_RS09335	COG0436	Aminotransferase
HZR12_RS09360	COG2267	carboxylic ester hydrolase activity
HZR12_RS09370	COG1169	isochorismate synthase
HZR12_RS09375	COG1575	Belongs to the MenA family. Type 1 subfamily
HZR12_RS09380	COG0456	acetyltransferase
HZR12_RS09385	COG2314	TM2 domain
HZR12_RS09395	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HZR12_RS09455	COG4873	Protein conserved in bacteria
HZR12_RS09470	COG4903	ComK protein
HZR12_RS09485	COG0737	Belongs to the 5'-nucleotidase family
HZR12_RS09490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HZR12_RS09500	COG0861	Integral membrane protein TerC family
HZR12_RS09540	COG1115	amino acid carrier protein
HZR12_RS09545	COG0628	permease
HZR12_RS09555	COG0475	glutathione-regulated potassium exporter activity
HZR12_RS09555	COG0569	domain protein
HZR12_RS09560	COG2239	Acts as a magnesium transporter
HZR12_RS09565	COG0564	pseudouridine synthase activity
HZR12_RS09575	COG2357	RelA SpoT domain protein
HZR12_RS09590	COG2346	COG2346, Truncated hemoglobins
HZR12_RS09600	COG1164	Oligoendopeptidase f
HZR12_RS09625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZR12_RS09630	COG0601	transmembrane transport
HZR12_RS09635	COG4608	Belongs to the ABC transporter superfamily
HZR12_RS09640	COG0444	Belongs to the ABC transporter superfamily
HZR12_RS09645	COG0747	negative chemotaxis
HZR12_RS09650	COG4166	transmembrane transport
HZR12_RS09655	COG4608	Belongs to the ABC transporter superfamily
HZR12_RS09660	COG0444	Belongs to the ABC transporter superfamily
HZR12_RS09665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZR12_RS09670	COG0601	transmembrane transport
HZR12_RS09700	COG1881	PFAM PEBP family protein
HZR12_RS09715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HZR12_RS09740	COG0561	phosphatase activity
HZR12_RS09780	COG0398	Pfam SNARE associated Golgi protein
HZR12_RS09800	COG0584	glycerophosphoryl diester phosphodiesterase
HZR12_RS09815	COG1902	pentaerythritol trinitrate reductase activity
HZR12_RS09820	COG1098	S1 RNA binding domain
HZR12_RS09840	COG2946	Replication initiation factor
HZR12_RS09860	COG0433	COG0433 Predicted ATPase
HZR12_RS09865	COG1674	ftsk spoiiie
HZR12_RS09875	COG1388	LysM domain
HZR12_RS09875	COG3942	CHAP domain
HZR12_RS09895	COG2826	transposase and inactivated derivatives, IS30 family
HZR12_RS09950	COG2050	protein possibly involved in aromatic compounds catabolism
HZR12_RS09955	COG2056	Na+-H+ antiporter family
HZR12_RS09960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HZR12_RS09970	COG0316	Belongs to the HesB IscA family
HZR12_RS09980	COG1252	NADH dehydrogenase
HZR12_RS09985	COG4837	Protein of unknown function (DUF1462)
HZR12_RS09990	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HZR12_RS09995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HZR12_RS10005	COG1696	Membrane protein involved in D-alanine export
HZR12_RS10035	COG2445	Protein of unknown function DUF86
HZR12_RS10045	COG4470	Protein conserved in bacteria
HZR12_RS10060	COG0730	response to heat
HZR12_RS10065	COG1801	Protein of unknown function DUF72
HZR12_RS10080	COG1253	flavin adenine dinucleotide binding
HZR12_RS10120	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZR12_RS10120	COG1388	LysM domain
HZR12_RS10155	COG0739	heme binding
HZR12_RS10210	COG0740	serine-type endopeptidase activity
HZR12_RS10255	COG0756	dUTP diphosphatase activity
HZR12_RS10310	COG1484	DNA-dependent DNA replication
HZR12_RS10425	COG0822	iron-sulfur transferase activity
HZR12_RS10435	COG0719	Fe-S assembly protein
HZR12_RS10440	COG0396	ATPase activity
HZR12_RS10455	COG1464	Belongs to the NlpA lipoprotein family
HZR12_RS10460	COG2011	ABC-type metal ion transport system permease component
HZR12_RS10475	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HZR12_RS10480	COG3878	Protein conserved in bacteria
HZR12_RS10490	COG1393	Belongs to the ArsC family
HZR12_RS10495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZR12_RS10520	COG1279	arginine transmembrane transporter activity
HZR12_RS10525	COG0406	alpha-ribazole phosphatase activity
HZR12_RS10565	COG1278	Cold shock
HZR12_RS10630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HZR12_RS10635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZR12_RS10650	COG5484	DNA packaging
HZR12_RS10650	COG3728	DNA packaging
HZR12_RS10750	COG0557	exoribonuclease II activity
HZR12_RS10755	COG1647	Serine aminopeptidase, S33
HZR12_RS10760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HZR12_RS10820	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HZR12_RS10875	COG3942	CHAP domain
HZR12_RS10875	COG1388	LysM domain
HZR12_RS10905	COG1040	competence protein
HZR12_RS10910	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HZR12_RS10920	COG1739	Uncharacterized protein family UPF0029
HZR12_RS10925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HZR12_RS10980	COG4607	ABC-type enterochelin transport system periplasmic component
HZR12_RS10985	COG4604	ABC transporter, ATP-binding protein
HZR12_RS10990	COG4605	iron ion homeostasis
HZR12_RS10995	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZR12_RS11005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZR12_RS11010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZR12_RS11030	COG3104	oligopeptide transport
HZR12_RS11055	COG1174	glycine betaine transport
HZR12_RS11060	COG0517	IMP dehydrogenase activity
HZR12_RS11060	COG1125	glycine betaine transport
HZR12_RS11065	COG0514	ATP-dependent DNA helicase (RecQ)
HZR12_RS11070	COG0488	(ABC) transporter
HZR12_RS11100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HZR12_RS11105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HZR12_RS11105	COG0512	Glutamine amidotransferase of anthranilate synthase
HZR12_RS11115	COG0720	synthase
HZR12_RS11155	COG2801	Transposase and inactivated derivatives
HZR12_RS11160	COG0463	Glycosyl transferase, family 2
HZR12_RS11165	COG0656	L-ascorbic acid biosynthetic process
HZR12_RS11170	COG1253	flavin adenine dinucleotide binding
HZR12_RS11175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HZR12_RS11180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZR12_RS11180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZR12_RS11180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZR12_RS11185	COG1105	Belongs to the carbohydrate kinase PfkB family
HZR12_RS11190	COG1349	DNA-binding transcription factor activity
HZR12_RS11195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HZR12_RS11230	COG0471	metal ion transport
HZR12_RS11240	COG4989	oxidoreductase activity
HZR12_RS11245	COG0523	cobalamin synthesis protein
HZR12_RS11255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HZR12_RS11260	COG4988	ABC transporter
HZR12_RS11280	COG1611	Belongs to the LOG family
HZR12_RS11310	COG2839	Protein conserved in bacteria
HZR12_RS11315	COG2814	Major facilitator Superfamily
HZR12_RS11320	COG0583	DNA-binding transcription factor activity
HZR12_RS11350	COG4977	sequence-specific DNA binding
HZR12_RS11350	COG1917	Cupin 2, conserved barrel domain protein
HZR12_RS11360	COG3942	CHAP domain
HZR12_RS11360	COG1388	LysM domain
HZR12_RS11365	COG0306	phosphate transporter
HZR12_RS11370	COG1392	Phosphate transport regulator
HZR12_RS11375	COG0577	efflux transmembrane transporter activity
HZR12_RS11380	COG1136	(ABC) transporter
HZR12_RS11395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZR12_RS11415	COG3949	Membrane
HZR12_RS11425	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HZR12_RS11435	COG2376	Dihydroxyacetone kinase
HZR12_RS11440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZR12_RS11445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZR12_RS11450	COG1120	ATPase activity
HZR12_RS11455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZR12_RS11465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HZR12_RS11470	COG1132	(ABC) transporter
HZR12_RS11475	COG1686	Belongs to the peptidase S11 family
HZR12_RS11480	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HZR12_RS11485	COG1216	Glycosyl transferase, family 2
HZR12_RS11490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HZR12_RS11495	COG1682	transport, permease protein
HZR12_RS11505	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HZR12_RS11515	COG1321	iron dependent repressor
HZR12_RS11520	COG1121	(ABC) transporter
HZR12_RS11525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HZR12_RS11530	COG0803	Belongs to the bacterial solute-binding protein 9 family
HZR12_RS11575	COG4974	Belongs to the 'phage' integrase family
HZR12_RS11625	COG4139	cobalamin transport
HZR12_RS11630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZR12_RS11665	COG1078	dGTPase activity
HZR12_RS11675	COG0655	NAD(P)H dehydrogenase (quinone) activity
HZR12_RS11680	COG0667	Aldo Keto reductase
HZR12_RS11765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZR12_RS11785	COG0083	homoserine kinase activity
HZR12_RS11790	COG0095	Lipoate-protein ligase
HZR12_RS11880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HZR12_RS11895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HZR12_RS11925	COG0561	phosphatase activity
HZR12_RS11935	COG1428	Deoxynucleoside kinase
HZR12_RS11940	COG1428	Deoxynucleoside kinase
HZR12_RS11945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HZR12_RS11975	COG1473	amidohydrolase
HZR12_RS12015	COG2813	Specifically methylates the guanine in position
HZR12_RS12070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HZR12_RS12090	COG4956	integral membrane protein (PIN domain superfamily)
HZR12_RS12095	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HZR12_RS12110	COG3880	PFAM UvrB UvrC protein
HZR12_RS12120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HZR12_RS12135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZR12_RS12230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HZR12_RS12255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HZR12_RS12270	COG1098	S1 RNA binding domain
HZR12_RS12280	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HZR12_RS12285	COG3956	TIGRFAM MazG family protein
HZR12_RS12290	COG2244	polysaccharide biosynthetic process
HZR12_RS12330	COG0251	oxidation-reduction process
HZR12_RS12335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HZR12_RS12345	COG4466	Protein conserved in bacteria
HZR12_RS12355	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HZR12_RS12360	COG0084	hydrolase, TatD family'
HZR12_RS12370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HZR12_RS12380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HZR12_RS12390	COG1774	PSP1 C-terminal conserved region
HZR12_RS12395	COG0470	DNA polymerase III
HZR12_RS12400	COG3870	Protein conserved in bacteria
HZR12_RS12410	COG1982	Orn Lys Arg decarboxylase major
HZR12_RS12445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HZR12_RS12465	COG2188	Transcriptional regulator
HZR12_RS12470	COG0366	Alpha amylase catalytic
HZR12_RS12475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZR12_RS12475	COG1263	PTS System
HZR12_RS12485	COG0493	'glutamate synthase
HZR12_RS12490	COG0070	glutamate synthase
HZR12_RS12490	COG0069	glutamate synthase activity
HZR12_RS12490	COG0067	glutamate synthase
HZR12_RS12495	COG0583	DNA-binding transcription factor activity
HZR12_RS12530	COG1464	Belongs to the NlpA lipoprotein family
HZR12_RS12535	COG2011	ABC-type metal ion transport system permease component
HZR12_RS12545	COG0626	cystathionine gamma-synthase activity
HZR12_RS12550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HZR12_RS12555	COG0733	neurotransmitter:sodium symporter activity
HZR12_RS12565	COG1647	Serine aminopeptidase, S33
HZR12_RS12580	COG5609	conserved protein (DUF2294)
HZR12_RS12590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HZR12_RS12615	COG0523	cobalamin synthesis protein
HZR12_RS12770	COG3759	membrane
HZR12_RS12805	COG2233	PERMEase
HZR12_RS12835	COG1823	symporter activity
HZR12_RS12850	COG3634	alkyl hydroperoxide reductase activity
HZR12_RS12940	COG5484	DNA packaging
HZR12_RS12940	COG3728	DNA packaging
HZR12_RS13055	COG0012	GTP binding
HZR12_RS13060	COG4481	Protein conserved in bacteria
HZR12_RS13065	COG0668	transmembrane transport
HZR12_RS13070	COG1475	DNA binding
HZR12_RS13075	COG0626	cystathionine gamma-synthase activity
HZR12_RS13080	COG0626	cystathionine gamma-synthase activity
HZR12_RS13085	COG0646	methionine synthase
HZR12_RS13085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HZR12_RS13115	COG1131	(ABC) transporter
HZR12_RS13125	COG1476	TRANSCRIPTIONal
HZR12_RS13135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HZR12_RS13140	COG0805	protein transport
HZR12_RS13145	COG0672	)-iron permease
HZR12_RS13155	COG2822	iron ion transport
HZR12_RS13160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZR12_RS13175	COG0431	NADPH-dependent FMN reductase
HZR12_RS13180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZR12_RS13185	COG0346	lactoylglutathione lyase activity
HZR12_RS13190	COG2271	Major facilitator Superfamily
HZR12_RS13210	COG3711	transcriptional antiterminator
HZR12_RS13215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZR12_RS13225	COG3037	sugar-specific permease SgaT UlaA
HZR12_RS13255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZR12_RS13305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HZR12_RS13310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HZR12_RS13335	COG0577	efflux transmembrane transporter activity
HZR12_RS13340	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HZR12_RS13345	COG1114	Component of the transport system for branched-chain amino acids
HZR12_RS13435	COG2801	Transposase and inactivated derivatives
HZR12_RS13510	COG3942	CHAP domain
HZR12_RS13510	COG1388	LysM domain
HZR12_RS13540	COG1131	(ABC) transporter
HZR12_RS13590	COG2226	methyltransferase
HZR12_RS13595	COG2723	6-phospho-beta-galactosidase activity
HZR12_RS13600	COG1263	PTS System
HZR12_RS13600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZR12_RS13600	COG2190	(PTS) system
HZR12_RS13605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZR12_RS13635	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HZR12_RS13660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HZR12_RS13675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZR12_RS13680	COG1957	nucleoside hydrolase
HZR12_RS13685	COG2190	(PTS) system
HZR12_RS13685	COG1263	PTS System
HZR12_RS13685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZR12_RS13710	COG3189	MarR family transcriptional regulator
HZR12_RS13715	COG0747	negative chemotaxis
HZR12_RS13720	COG1073	alpha beta
HZR12_RS13750	COG0318	PFAM AMP-dependent synthetase and ligase
HZR12_RS13755	COG1960	acyl-CoA dehydrogenase activity
HZR12_RS13765	COG0183	Belongs to the thiolase family
HZR12_RS13820	COG1755	Isoprenylcysteine carboxyl methyltransferase
HZR12_RS13830	COG0673	inositol 2-dehydrogenase activity
HZR12_RS13835	COG0673	inositol 2-dehydrogenase activity
HZR12_RS13840	COG3833	ABC-type maltose transport systems, permease component
HZR12_RS13845	COG1175	transmembrane transport
HZR12_RS13855	COG3842	ATPase activity
HZR12_RS13875	COG0405	Gamma-glutamyltransferase
HZR12_RS13900	COG2946	Replication initiation factor
HZR12_RS13920	COG0433	COG0433 Predicted ATPase
HZR12_RS13925	COG1674	ftsk spoiiie
HZR12_RS13935	COG5644	endopeptidase inhibitor activity
HZR12_RS13960	COG2826	transposase and inactivated derivatives, IS30 family
HZR12_RS13970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZR12_RS14000	COG1737	Transcriptional regulator
HZR12_RS14030	COG3961	Belongs to the TPP enzyme family
HZR12_RS14035	COG1335	isochorismatase
HZR12_RS14040	COG1114	Component of the transport system for branched-chain amino acids
HZR12_RS14070	COG2801	Transposase and inactivated derivatives
HZR12_RS14080	COG0583	DNA-binding transcription factor activity
HZR12_RS14085	COG2855	membrane
HZR12_RS14105	COG3682	Transcriptional regulator
HZR12_RS14145	COG1132	(ABC) transporter
HZR12_RS14150	COG1132	(ABC) transporter
HZR12_RS14170	COG3620	sequence-specific DNA binding
HZR12_RS14195	COG1131	(ABC) transporter
HZR12_RS14270	COG2801	Transposase and inactivated derivatives
HZR12_RS14280	COG1846	Transcriptional regulator
HZR12_RS14325	COG1438	arginine binding
HZR12_RS14345	COG3711	transcriptional antiterminator
HZR12_RS14345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZR12_RS14350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZR12_RS14350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZR12_RS14350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZR12_RS14355	COG1482	cell wall glycoprotein biosynthetic process
HZR12_RS14365	COG3942	CHAP domain
HZR12_RS14365	COG1705	Flagellar rod assembly protein muramidase FlgJ
HZR12_RS14370	COG1535	isochorismatase
HZR12_RS14370	COG3433	isochorismatase activity
HZR12_RS14385	COG0438	transferase activity, transferring glycosyl groups
HZR12_RS14400	COG1073	alpha beta
HZR12_RS14420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HZR12_RS14440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HZR12_RS14530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HZR12_RS14605	COG0471	metal ion transport
HZR12_RS14610	COG2962	Rard protein
HZR12_RS14620	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HZR12_RS14635	COG1136	(ABC) transporter
HZR12_RS14640	COG0577	efflux transmembrane transporter activity
HZR12_RS14650	COG1278	Cold shock
HZR12_RS14670	COG1475	DNA binding