locus-tag	class	description
DWB87_RS00015	COG2501	S4 domain
DWB87_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DWB87_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DWB87_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DWB87_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DWB87_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
DWB87_RS00110	COG4863	YycH protein
DWB87_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DWB87_RS00125	COG0737	Belongs to the 5'-nucleotidase family
DWB87_RS00150	COG2801	Transposase and inactivated derivatives
DWB87_RS00175	COG0456	acetyltransferase
DWB87_RS00190	COG0730	response to heat
DWB87_RS00195	COG1937	Protein conserved in bacteria
DWB87_RS00200	COG2210	Belongs to the sulfur carrier protein TusA family
DWB87_RS00205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWB87_RS00245	COG0655	NAD(P)H dehydrogenase (quinone) activity
DWB87_RS00260	COG0583	DNA-binding transcription factor activity
DWB87_RS00280	COG0823	Involved in the tonB-independent uptake of proteins
DWB87_RS00325	COG1473	amidohydrolase
DWB87_RS00335	COG1283	sodium-dependent phosphate transmembrane transporter activity
DWB87_RS00340	COG4716	Myosin-crossreactive antigen
DWB87_RS00350	COG1620	l-lactate permease
DWB87_RS00365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB87_RS00370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB87_RS00375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DWB87_RS00385	COG2423	ornithine cyclodeaminase activity
DWB87_RS00390	COG4264	IucA IucC family
DWB87_RS00395	COG2814	Major facilitator Superfamily
DWB87_RS00400	COG4264	IucA IucC family
DWB87_RS00405	COG4264	IucA IucC family
DWB87_RS00415	COG0019	diaminopimelate decarboxylase activity
DWB87_RS00420	COG1475	DNA binding
DWB87_RS00445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DWB87_RS00450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DWB87_RS00455	COG0438	transferase activity, transferring glycosyl groups
DWB87_RS00485	COG0813	purine-nucleoside phosphorylase activity
DWB87_RS00490	COG2814	Major facilitator Superfamily
DWB87_RS00510	COG3639	organic phosphonate transmembrane transporter activity
DWB87_RS00530	COG0737	Belongs to the 5'-nucleotidase family
DWB87_RS00570	COG1454	alcohol dehydrogenase
DWB87_RS00570	COG1012	belongs to the aldehyde dehydrogenase family
DWB87_RS00595	COG1086	Polysaccharide biosynthesis protein
DWB87_RS00605	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DWB87_RS00635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DWB87_RS00645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DWB87_RS00650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DWB87_RS00660	COG2832	Protein of unknown function (DUF454)
DWB87_RS00700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DWB87_RS00705	COG1960	acyl-CoA dehydrogenase activity
DWB87_RS00710	COG5609	conserved protein (DUF2294)
DWB87_RS00760	COG1114	Component of the transport system for branched-chain amino acids
DWB87_RS00765	COG1335	isochorismatase
DWB87_RS00770	COG3961	Belongs to the TPP enzyme family
DWB87_RS00800	COG1737	Transcriptional regulator
DWB87_RS00825	COG1136	(ABC) transporter
DWB87_RS00830	COG0577	efflux transmembrane transporter activity
DWB87_RS00830	COG1136	(ABC) transporter
DWB87_RS00850	COG1131	(ABC) transporter
DWB87_RS00865	COG0601	transmembrane transport
DWB87_RS00870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DWB87_RS00880	COG0405	Gamma-glutamyltransferase
DWB87_RS00900	COG3842	ATPase activity
DWB87_RS00910	COG1175	transmembrane transport
DWB87_RS00915	COG3833	ABC-type maltose transport systems, permease component
DWB87_RS00920	COG0673	inositol 2-dehydrogenase activity
DWB87_RS00925	COG0673	inositol 2-dehydrogenase activity
DWB87_RS00935	COG1755	Isoprenylcysteine carboxyl methyltransferase
DWB87_RS00995	COG0183	Belongs to the thiolase family
DWB87_RS01005	COG1960	acyl-CoA dehydrogenase activity
DWB87_RS01010	COG0318	PFAM AMP-dependent synthetase and ligase
DWB87_RS01025	COG0747	negative chemotaxis
DWB87_RS01030	COG3189	MarR family transcriptional regulator
DWB87_RS01055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB87_RS01055	COG2190	(PTS) system
DWB87_RS01055	COG1263	PTS System
DWB87_RS01060	COG1957	nucleoside hydrolase
DWB87_RS01080	COG3414	Phosphotransferase system galactitol-specific IIB component
DWB87_RS01085	COG3775	system Galactitol-specific IIC component
DWB87_RS01090	COG1063	alcohol dehydrogenase
DWB87_RS01100	COG1063	alcohol dehydrogenase
DWB87_RS01110	COG1063	alcohol dehydrogenase
DWB87_RS01115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB87_RS01120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB87_RS01130	COG1063	alcohol dehydrogenase
DWB87_RS01135	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB87_RS01170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DWB87_RS01175	COG2190	(PTS) system
DWB87_RS01175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB87_RS01175	COG1263	PTS System
DWB87_RS01180	COG2723	6-phospho-beta-galactosidase activity
DWB87_RS01185	COG2226	methyltransferase
DWB87_RS01240	COG1131	(ABC) transporter
DWB87_RS01260	COG3942	CHAP domain
DWB87_RS01260	COG1388	LysM domain
DWB87_RS01390	COG1114	Component of the transport system for branched-chain amino acids
DWB87_RS01400	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DWB87_RS01410	COG0577	efflux transmembrane transporter activity
DWB87_RS01440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DWB87_RS01445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DWB87_RS01470	COG3314	Sporulation integral membrane protein YlbJ
DWB87_RS01495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB87_RS01525	COG3037	sugar-specific permease SgaT UlaA
DWB87_RS01535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB87_RS01540	COG3711	transcriptional antiterminator
DWB87_RS01560	COG2271	Major facilitator Superfamily
DWB87_RS01565	COG0346	lactoylglutathione lyase activity
DWB87_RS01570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB87_RS01575	COG0431	NADPH-dependent FMN reductase
DWB87_RS01585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DWB87_RS01600	COG0672	)-iron permease
DWB87_RS01605	COG0805	protein transport
DWB87_RS01610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DWB87_RS01620	COG1476	TRANSCRIPTIONal
DWB87_RS01630	COG1131	(ABC) transporter
DWB87_RS01660	COG0646	methionine synthase
DWB87_RS01660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DWB87_RS01665	COG0626	cystathionine gamma-synthase activity
DWB87_RS01670	COG0626	cystathionine gamma-synthase activity
DWB87_RS01680	COG1475	DNA binding
DWB87_RS01685	COG0668	transmembrane transport
DWB87_RS01690	COG4481	Protein conserved in bacteria
DWB87_RS01695	COG0012	GTP binding
DWB87_RS01795	COG1823	symporter activity
DWB87_RS01830	COG2233	PERMEase
DWB87_RS01900	COG1683	Conserved Protein
DWB87_RS01910	COG3759	membrane
DWB87_RS02045	COG0523	cobalamin synthesis protein
DWB87_RS02070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DWB87_RS02080	COG5609	conserved protein (DUF2294)
DWB87_RS02095	COG1647	Serine aminopeptidase, S33
DWB87_RS02105	COG0733	neurotransmitter:sodium symporter activity
DWB87_RS02110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DWB87_RS02115	COG0626	cystathionine gamma-synthase activity
DWB87_RS02125	COG2011	ABC-type metal ion transport system permease component
DWB87_RS02130	COG1464	Belongs to the NlpA lipoprotein family
DWB87_RS02165	COG0583	DNA-binding transcription factor activity
DWB87_RS02170	COG0069	glutamate synthase activity
DWB87_RS02170	COG0070	glutamate synthase
DWB87_RS02170	COG0067	glutamate synthase
DWB87_RS02175	COG0493	'glutamate synthase
DWB87_RS02185	COG1263	PTS System
DWB87_RS02185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB87_RS02190	COG0366	Alpha amylase catalytic
DWB87_RS02195	COG2188	Transcriptional regulator
DWB87_RS02215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DWB87_RS02250	COG1982	Orn Lys Arg decarboxylase major
DWB87_RS02260	COG3870	Protein conserved in bacteria
DWB87_RS02265	COG0470	DNA polymerase III
DWB87_RS02270	COG1774	PSP1 C-terminal conserved region
DWB87_RS02280	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DWB87_RS02290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DWB87_RS02300	COG0084	hydrolase, TatD family'
DWB87_RS02305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DWB87_RS02315	COG4466	Protein conserved in bacteria
DWB87_RS02325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DWB87_RS02330	COG0251	oxidation-reduction process
DWB87_RS02370	COG2244	polysaccharide biosynthetic process
DWB87_RS02375	COG3956	TIGRFAM MazG family protein
DWB87_RS02380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DWB87_RS02390	COG1098	S1 RNA binding domain
DWB87_RS02405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DWB87_RS02430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DWB87_RS02525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DWB87_RS02540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DWB87_RS02565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DWB87_RS02570	COG4956	integral membrane protein (PIN domain superfamily)
DWB87_RS02590	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DWB87_RS02650	COG2813	Specifically methylates the guanine in position
DWB87_RS02690	COG1473	amidohydrolase
DWB87_RS02720	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DWB87_RS02725	COG1428	Deoxynucleoside kinase
DWB87_RS02730	COG1428	Deoxynucleoside kinase
DWB87_RS02740	COG0561	phosphatase activity
DWB87_RS02770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DWB87_RS02885	COG0095	Lipoate-protein ligase
DWB87_RS02890	COG0083	homoserine kinase activity
DWB87_RS02910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DWB87_RS03000	COG0667	Aldo Keto reductase
DWB87_RS03005	COG0655	NAD(P)H dehydrogenase (quinone) activity
DWB87_RS03015	COG1078	dGTPase activity
DWB87_RS03050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DWB87_RS03055	COG4139	cobalamin transport
DWB87_RS03105	COG4974	Belongs to the 'phage' integrase family
DWB87_RS03150	COG0803	Belongs to the bacterial solute-binding protein 9 family
DWB87_RS03155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DWB87_RS03160	COG1121	(ABC) transporter
DWB87_RS03165	COG1321	iron dependent repressor
DWB87_RS03175	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DWB87_RS03185	COG1682	transport, permease protein
DWB87_RS03190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DWB87_RS03200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DWB87_RS03205	COG1686	Belongs to the peptidase S11 family
DWB87_RS03210	COG1132	(ABC) transporter
DWB87_RS03215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DWB87_RS03225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DWB87_RS03230	COG1120	ATPase activity
DWB87_RS03235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB87_RS03240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB87_RS03245	COG2376	Dihydroxyacetone kinase
DWB87_RS03255	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DWB87_RS03265	COG3949	Membrane
DWB87_RS03285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DWB87_RS03300	COG1136	(ABC) transporter
DWB87_RS03305	COG0577	efflux transmembrane transporter activity
DWB87_RS03310	COG1392	Phosphate transport regulator
DWB87_RS03315	COG0306	phosphate transporter
DWB87_RS03320	COG3942	CHAP domain
DWB87_RS03320	COG1388	LysM domain
DWB87_RS03330	COG1917	Cupin 2, conserved barrel domain protein
DWB87_RS03330	COG4977	sequence-specific DNA binding
DWB87_RS03360	COG0583	DNA-binding transcription factor activity
DWB87_RS03365	COG2814	Major facilitator Superfamily
DWB87_RS03370	COG2839	Protein conserved in bacteria
DWB87_RS03400	COG1611	Belongs to the LOG family
DWB87_RS03420	COG4988	ABC transporter
DWB87_RS03425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DWB87_RS03440	COG4989	oxidoreductase activity
DWB87_RS03450	COG0471	metal ion transport
DWB87_RS03455	COG0415	Belongs to the DNA photolyase family
DWB87_RS03485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DWB87_RS03490	COG1349	DNA-binding transcription factor activity
DWB87_RS03495	COG1105	Belongs to the carbohydrate kinase PfkB family
DWB87_RS03500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWB87_RS03500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB87_RS03500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWB87_RS03505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DWB87_RS03510	COG1253	flavin adenine dinucleotide binding
DWB87_RS03515	COG0656	L-ascorbic acid biosynthetic process
DWB87_RS03520	COG0463	Glycosyl transferase, family 2
DWB87_RS03555	COG0720	synthase
DWB87_RS03565	COG0512	Glutamine amidotransferase of anthranilate synthase
DWB87_RS03565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DWB87_RS03570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DWB87_RS03600	COG0488	(ABC) transporter
DWB87_RS03605	COG0514	ATP-dependent DNA helicase (RecQ)
DWB87_RS03610	COG1125	glycine betaine transport
DWB87_RS03610	COG0517	IMP dehydrogenase activity
DWB87_RS03615	COG1174	glycine betaine transport
DWB87_RS03640	COG3104	oligopeptide transport
DWB87_RS03670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DWB87_RS03675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DWB87_RS03685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB87_RS03690	COG4605	iron ion homeostasis
DWB87_RS03695	COG4604	ABC transporter, ATP-binding protein
DWB87_RS03700	COG4607	ABC-type enterochelin transport system periplasmic component
DWB87_RS03755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DWB87_RS03760	COG1739	Uncharacterized protein family UPF0029
DWB87_RS03770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DWB87_RS03775	COG1040	competence protein
DWB87_RS03805	COG3942	CHAP domain
DWB87_RS03805	COG1388	LysM domain
DWB87_RS03860	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DWB87_RS03925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DWB87_RS03930	COG1647	Serine aminopeptidase, S33
DWB87_RS03935	COG0557	exoribonuclease II activity
DWB87_RS03995	COG1278	Cold shock
DWB87_RS04035	COG0406	alpha-ribazole phosphatase activity
DWB87_RS04040	COG1279	arginine transmembrane transporter activity
DWB87_RS04065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DWB87_RS04070	COG1393	Belongs to the ArsC family
DWB87_RS04085	COG3878	Protein conserved in bacteria
DWB87_RS04095	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DWB87_RS04110	COG2011	ABC-type metal ion transport system permease component
DWB87_RS04115	COG1464	Belongs to the NlpA lipoprotein family
DWB87_RS04130	COG0396	ATPase activity
DWB87_RS04135	COG0719	Fe-S assembly protein
DWB87_RS04145	COG0822	iron-sulfur transferase activity
DWB87_RS04170	COG1253	flavin adenine dinucleotide binding
DWB87_RS04180	COG1801	Protein of unknown function DUF72
DWB87_RS04185	COG0730	response to heat
DWB87_RS04200	COG4470	Protein conserved in bacteria
DWB87_RS04210	COG2445	Protein of unknown function DUF86
DWB87_RS04240	COG1696	Membrane protein involved in D-alanine export
DWB87_RS04250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DWB87_RS04255	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DWB87_RS04260	COG4837	Protein of unknown function (DUF1462)
DWB87_RS04265	COG1252	NADH dehydrogenase
DWB87_RS04275	COG0316	Belongs to the HesB IscA family
DWB87_RS04285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DWB87_RS04290	COG2056	Na+-H+ antiporter family
DWB87_RS04295	COG2050	protein possibly involved in aromatic compounds catabolism
DWB87_RS04350	COG1098	S1 RNA binding domain
DWB87_RS04355	COG1902	pentaerythritol trinitrate reductase activity
DWB87_RS04370	COG0584	glycerophosphoryl diester phosphodiesterase
DWB87_RS04390	COG0398	Pfam SNARE associated Golgi protein
DWB87_RS04430	COG0561	phosphatase activity
DWB87_RS04455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DWB87_RS04470	COG1881	PFAM PEBP family protein
DWB87_RS04500	COG0601	transmembrane transport
DWB87_RS04505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DWB87_RS04510	COG0444	Belongs to the ABC transporter superfamily
DWB87_RS04515	COG4608	Belongs to the ABC transporter superfamily
DWB87_RS04520	COG4166	transmembrane transport
DWB87_RS04525	COG0747	negative chemotaxis
DWB87_RS04530	COG0444	Belongs to the ABC transporter superfamily
DWB87_RS04540	COG0601	transmembrane transport
DWB87_RS04545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DWB87_RS04570	COG1164	Oligoendopeptidase f
DWB87_RS04580	COG2346	COG2346, Truncated hemoglobins
DWB87_RS04595	COG2357	RelA SpoT domain protein
DWB87_RS04605	COG0564	pseudouridine synthase activity
DWB87_RS04610	COG2239	Acts as a magnesium transporter
DWB87_RS04615	COG0475	glutathione-regulated potassium exporter activity
DWB87_RS04615	COG0569	domain protein
DWB87_RS04625	COG0628	permease
DWB87_RS04630	COG1115	amino acid carrier protein
DWB87_RS04670	COG0861	Integral membrane protein TerC family
DWB87_RS04680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DWB87_RS04685	COG0737	Belongs to the 5'-nucleotidase family
DWB87_RS04700	COG4903	ComK protein
DWB87_RS04715	COG4873	Protein conserved in bacteria
DWB87_RS04775	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DWB87_RS04785	COG2314	TM2 domain
DWB87_RS04790	COG0456	acetyltransferase
DWB87_RS04795	COG1575	Belongs to the MenA family. Type 1 subfamily
DWB87_RS04805	COG1169	isochorismate synthase
DWB87_RS04815	COG2267	carboxylic ester hydrolase activity
DWB87_RS04845	COG0436	Aminotransferase
DWB87_RS04850	COG3594	Acyltransferase
DWB87_RS04880	COG1316	TRANSCRIPTIONal
DWB87_RS04925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DWB87_RS04940	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DWB87_RS04970	COG0138	bifunctional purine biosynthesis protein purh
DWB87_RS04980	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DWB87_RS04985	COG4172	Belongs to the ABC transporter superfamily
DWB87_RS04990	COG4721	ABC-type cobalt transport system, permease component
DWB87_RS05015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DWB87_RS05035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DWB87_RS05040	COG1271	oxidase subunit
DWB87_RS05045	COG1294	oxidase, subunit
DWB87_RS05050	COG0569	domain protein
DWB87_RS05115	COG1176	ABC-type spermidine putrescine transport system, permease component I
DWB87_RS05120	COG1177	transmembrane transport
DWB87_RS05125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DWB87_RS05150	COG0483	inositol monophosphate 1-phosphatase activity
DWB87_RS05160	COG1217	gtp-binding protein TYPA
DWB87_RS05170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DWB87_RS05180	COG0772	Belongs to the SEDS family
DWB87_RS05210	COG3679	Belongs to the UPF0342 family
DWB87_RS05230	COG0742	ribosomal rna small subunit methyltransferase
DWB87_RS05280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DWB87_RS05355	COG0305	Participates in initiation and elongation during chromosome replication
DWB87_RS05455	COG4695	Portal protein
DWB87_RS05510	COG0739	heme binding
DWB87_RS05555	COG0860	N-Acetylmuramoyl-L-alanine amidase
DWB87_RS05555	COG1388	LysM domain
DWB87_RS05600	COG4509	Sortase family
DWB87_RS05615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DWB87_RS05645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DWB87_RS05645	COG1796	DNA polymerase
DWB87_RS05670	COG2009	succinate dehydrogenase
DWB87_RS05675	COG1053	succinate dehydrogenase
DWB87_RS05680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DWB87_RS05790	COG1288	antiporter activity
DWB87_RS05825	COG1011	Hydrolase
DWB87_RS05850	COG4839	cell division protein FtsL
DWB87_RS05855	COG0768	penicillin binding
DWB87_RS05870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DWB87_RS05890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DWB87_RS05900	COG0762	integral membrane protein
DWB87_RS05905	COG2302	S4 RNA-binding domain
DWB87_RS05910	COG3599	regulation of cell shape
DWB87_RS05920	COG2514	catechol 2,3-dioxygenase activity
DWB87_RS05935	COG0564	pseudouridine synthase activity
DWB87_RS05945	COG2233	PERMEase
DWB87_RS05990	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DWB87_RS06005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DWB87_RS06010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DWB87_RS06020	COG2314	TM2 domain
DWB87_RS06035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DWB87_RS06035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DWB87_RS06045	COG0631	protein serine/threonine phosphatase activity
DWB87_RS06060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DWB87_RS06075	COG1302	Protein conserved in bacteria
DWB87_RS06125	COG1196	nuclear chromosome segregation
DWB87_RS06130	COG0552	protein localization to endoplasmic reticulum
DWB87_RS06140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DWB87_RS06205	COG0758	DNA mediated transformation
DWB87_RS06300	COG0195	Participates in both transcription termination and antitermination
DWB87_RS06305	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DWB87_RS06330	COG0196	riboflavin kinase activity
DWB87_RS06355	COG2188	Transcriptional regulator
DWB87_RS06365	COG0612	Peptidase, M16
DWB87_RS06370	COG0300	oxidoreductase activity
DWB87_RS06390	COG1546	Belongs to the CinA family
DWB87_RS06390	COG1058	Belongs to the CinA family
DWB87_RS06410	COG1692	metallophosphoesterase
DWB87_RS06415	COG0674	pyruvate-flavodoxin oxidoreductase activity
DWB87_RS06415	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DWB87_RS06420	COG1013	pyruvate-flavodoxin oxidoreductase activity
DWB87_RS06455	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DWB87_RS06460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DWB87_RS06485	COG1923	regulation of RNA biosynthetic process
DWB87_RS06495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DWB87_RS06500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DWB87_RS06505	COG0789	Transcriptional regulator
DWB87_RS06630	COG2197	response regulator
DWB87_RS06640	COG1525	nuclease
DWB87_RS06655	COG0527	aspartate kinase activity
DWB87_RS06660	COG0460	homoserine dehydrogenase
DWB87_RS06665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DWB87_RS06690	COG0833	amino acid
DWB87_RS06720	COG2340	Cysteine-rich secretory protein family
DWB87_RS06755	COG4846	Membrane protein involved in cytochrome C biogenesis
DWB87_RS06775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DWB87_RS06785	COG0824	Thioesterase
DWB87_RS06810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DWB87_RS06815	COG1115	amino acid carrier protein
DWB87_RS06830	COG0628	permease
DWB87_RS06855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DWB87_RS06865	COG1363	Peptidase, m42
DWB87_RS06870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DWB87_RS06875	COG0512	Glutamine amidotransferase of anthranilate synthase
DWB87_RS06965	COG0704	Plays a role in the regulation of phosphate uptake
DWB87_RS06975	COG0581	inorganic phosphate transmembrane transporter activity
DWB87_RS06980	COG0573	inorganic phosphate transmembrane transporter activity
DWB87_RS07000	COG0488	(ABC) transporter
DWB87_RS07005	COG0527	aspartate kinase activity
DWB87_RS07010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DWB87_RS07090	COG4548	von Willebrand factor, type A
DWB87_RS07095	COG0714	Associated with various cellular activities
DWB87_RS07140	COG0671	phosphoesterase, PA-phosphatase related
DWB87_RS07220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DWB87_RS07240	COG0531	amino acid
DWB87_RS07255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DWB87_RS07260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DWB87_RS07275	COG0116	Belongs to the methyltransferase superfamily
DWB87_RS07315	COG4499	WXG100 protein secretion system (Wss), protein YukC
DWB87_RS07315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DWB87_RS07325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DWB87_RS07330	COG3935	DnaD domain protein
DWB87_RS07355	COG0438	transferase activity, transferring glycosyl groups
DWB87_RS07360	COG1694	Mazg nucleotide pyrophosphohydrolase
DWB87_RS07365	COG2738	Putative neutral zinc metallopeptidase
DWB87_RS07370	COG4347	Protein of unknown function (DUF1405)
DWB87_RS07410	COG0142	geranyltranstransferase activity
DWB87_RS07455	COG0492	ferredoxin-NADP+ reductase activity
DWB87_RS07470	COG0514	ATP-dependent DNA helicase (RecQ)
DWB87_RS07480	COG1141	Ferredoxin
DWB87_RS07515	COG5002	protein histidine kinase activity
DWB87_RS07520	COG0745	RESPONSE REGULATOR receiver
DWB87_RS07525	COG1187	pseudouridine synthase activity
DWB87_RS07550	COG0735	belongs to the Fur family
DWB87_RS07555	COG0494	nUDIX hydrolase
DWB87_RS07560	COG0667	Aldo Keto reductase
DWB87_RS07570	COG4221	oxidoreductase activity
DWB87_RS07585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DWB87_RS07595	COG0366	Alpha amylase catalytic
DWB87_RS07600	COG1609	Transcriptional regulator
DWB87_RS07620	COG2195	Cleaves the N-terminal amino acid of tripeptides
DWB87_RS07630	COG4129	membrane
DWB87_RS07640	COG0508	dehydrogenase complex catalyzes the overall conversion of
DWB87_RS07645	COG0022	dehydrogenase e1 component
DWB87_RS07650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DWB87_RS07655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DWB87_RS07660	COG0497	DNA recombination
DWB87_RS07690	COG1302	Protein conserved in bacteria
DWB87_RS07695	COG0439	Biotin carboxylase
DWB87_RS07700	COG0511	ligase activity, forming carbon-carbon bonds
DWB87_RS07710	COG0006	proline dipeptidase activity
DWB87_RS07725	COG0095	Lipoate-protein ligase
DWB87_RS07730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DWB87_RS07775	COG4537	Required for transformation and DNA binding
DWB87_RS07780	COG1459	type II secretion system
DWB87_RS07785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DWB87_RS07790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWB87_RS07795	COG0011	TIGRFAM Protein of
DWB87_RS07800	COG1940	carbohydrate kinase activity
DWB87_RS07805	COG4483	Protein conserved in bacteria
DWB87_RS07815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DWB87_RS07825	COG0768	penicillin binding
DWB87_RS07840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DWB87_RS07845	COG1121	(ABC) transporter
DWB87_RS07855	COG0513	Belongs to the DEAD box helicase family
DWB87_RS07865	COG2384	SAM-dependent methyltransferase
DWB87_RS07885	COG0517	IMP dehydrogenase activity
DWB87_RS07905	COG0295	cytidine deaminase activity
DWB87_RS07920	COG1702	phosphate starvation-inducible protein PhoH
DWB87_RS07935	COG1030	water channel activity
DWB87_RS07945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DWB87_RS07950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DWB87_RS07980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DWB87_RS07995	COG1466	dna polymerase III delta subunit
DWB87_RS08000	COG2333	competence protein COMEC
DWB87_RS08000	COG0658	competence protein
DWB87_RS08005	COG2131	deaminase
DWB87_RS08015	COG2226	methyltransferase
DWB87_RS08020	COG0799	negative regulation of ribosome biogenesis
DWB87_RS08025	COG1713	HD superfamily hydrolase involved in NAD metabolism
DWB87_RS08035	COG1534	Rna-binding protein
DWB87_RS08045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DWB87_RS08050	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DWB87_RS08070	COG3177	Filamentation induced by cAMP protein fic
DWB87_RS08075	COG1914	H( )-stimulated, divalent metal cation uptake system
DWB87_RS08085	COG0439	Biotin carboxylase
DWB87_RS08090	COG0511	ligase activity, forming carbon-carbon bonds
DWB87_RS08095	COG1984	allophanate hydrolase subunit 2
DWB87_RS08100	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DWB87_RS08115	COG0826	peptidase U32
DWB87_RS08120	COG0826	peptidase U32
DWB87_RS08150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DWB87_RS08165	COG1104	cysteine desulfurase activity
DWB87_RS08170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DWB87_RS08180	COG3237	CsbD-like
DWB87_RS08185	COG1959	2 iron, 2 sulfur cluster binding
DWB87_RS08190	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DWB87_RS08195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DWB87_RS08240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DWB87_RS08240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DWB87_RS08245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DWB87_RS08245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DWB87_RS08250	COG1862	Preprotein translocase
DWB87_RS08290	COG2868	ribosomal protein
DWB87_RS08335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DWB87_RS08340	COG0285	dihydrofolate synthase activity
DWB87_RS08350	COG2818	Glycosylase
DWB87_RS08385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DWB87_RS08420	COG4112	unkown
DWB87_RS08440	COG0833	amino acid
DWB87_RS08455	COG1484	DNA-dependent DNA replication
DWB87_RS08485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DWB87_RS08485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DWB87_RS08495	COG5002	protein histidine kinase activity
DWB87_RS08500	COG0745	RESPONSE REGULATOR receiver
DWB87_RS08510	COG0372	Belongs to the citrate synthase family
DWB87_RS08515	COG1113	amino acid transport
DWB87_RS08540	COG0281	malic enzyme
DWB87_RS08550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DWB87_RS08555	COG4109	DRTGG domain
DWB87_RS08595	COG0827	DNA restriction-modification system
DWB87_RS08605	COG0730	response to heat
DWB87_RS08615	COG1104	cysteine desulfurase activity
DWB87_RS08630	COG1956	GAF domain-containing protein
DWB87_RS08645	COG0584	glycerophosphoryl diester phosphodiesterase
DWB87_RS08650	COG1764	response to oxidative stress
DWB87_RS08655	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DWB87_RS08660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DWB87_RS08675	COG1263	PTS System
DWB87_RS08675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB87_RS08680	COG0204	Acyl-transferase
DWB87_RS08685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DWB87_RS08720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DWB87_RS08725	COG0454	-acetyltransferase
DWB87_RS08745	COG1605	Chorismate mutase
DWB87_RS08745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DWB87_RS08770	COG1674	ftsk spoiiie
DWB87_RS08775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DWB87_RS08785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DWB87_RS08790	COG1363	Peptidase, m42
DWB87_RS08800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWB87_RS08810	COG0510	thiamine kinase activity
DWB87_RS08830	COG1187	pseudouridine synthase activity
DWB87_RS08835	COG2244	polysaccharide biosynthetic process
DWB87_RS08840	COG2081	HI0933 family
DWB87_RS08860	COG2814	Major facilitator Superfamily
DWB87_RS08865	COG1242	4 iron, 4 sulfur cluster binding
DWB87_RS08870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DWB87_RS08880	COG2267	carboxylic ester hydrolase activity
DWB87_RS08915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DWB87_RS08915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DWB87_RS08935	COG4193	domain, Protein
DWB87_RS08935	COG3266	domain, Protein
DWB87_RS08935	COG5632	N-Acetylmuramoyl-L-alanine amidase
DWB87_RS08965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DWB87_RS08985	COG0656	L-ascorbic acid biosynthetic process
DWB87_RS09005	COG1506	peptidase
DWB87_RS09010	COG2816	NAD+ diphosphatase activity
DWB87_RS09185	COG1131	(ABC) transporter
DWB87_RS09305	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DWB87_RS09335	COG1131	(ABC) transporter
DWB87_RS09340	COG0537	adenosine 5'-monophosphoramidase activity
DWB87_RS09375	COG0420	3'-5' exonuclease activity
DWB87_RS09405	COG2197	response regulator
DWB87_RS09410	COG2203	Gaf domain
DWB87_RS09410	COG4585	Histidine kinase
DWB87_RS09415	COG0564	pseudouridine synthase activity
DWB87_RS09445	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DWB87_RS09450	COG1126	abc transporter atp-binding protein
DWB87_RS09455	COG0765	amino acid transport
DWB87_RS09615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DWB87_RS09620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DWB87_RS09630	COG4129	membrane
DWB87_RS09655	COG1988	membrane-bound metal-dependent
DWB87_RS09670	COG1134	teichoic acid transport
DWB87_RS09670	COG1388	LysM domain
DWB87_RS09700	COG0535	radical SAM domain protein
DWB87_RS09705	COG1607	acyl-coa hydrolase
DWB87_RS09710	COG2309	aminopeptidase activity
DWB87_RS09730	COG1295	ribonuclease BN
DWB87_RS09845	COG4851	CamS sex pheromone cAM373 precursor
DWB87_RS09855	COG0210	DNA helicase
DWB87_RS09865	COG4496	protein, YerC YecD
DWB87_RS09905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DWB87_RS09915	COG0077	Prephenate dehydratase
DWB87_RS09935	COG1335	isochorismatase
DWB87_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
DWB87_RS09960	COG3682	Transcriptional regulator
DWB87_RS09990	COG4974	Belongs to the 'phage' integrase family
DWB87_RS10045	COG1131	(ABC) transporter
DWB87_RS10060	COG1725	Transcriptional regulator
DWB87_RS10110	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DWB87_RS10115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DWB87_RS10120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DWB87_RS10150	COG5484	DNA packaging
DWB87_RS10150	COG3728	DNA packaging
DWB87_RS10240	COG0582	viral genome integration into host DNA
DWB87_RS10305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DWB87_RS10310	COG1621	beta-fructofuranosidase activity
DWB87_RS10315	COG1609	Transcriptional regulator
DWB87_RS10320	COG0004	ammonium transporteR
DWB87_RS10325	COG0425	Belongs to the sulfur carrier protein TusA family
DWB87_RS10330	COG2391	methyltransferase activity
DWB87_RS10340	COG0488	(ABC) transporter
DWB87_RS10350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DWB87_RS10360	COG0456	acetyltransferase
DWB87_RS10365	COG1214	PFAM Peptidase M22, glycoprotease
DWB87_RS10370	COG0802	atpase or kinase
DWB87_RS10385	COG0028	Belongs to the TPP enzyme family
DWB87_RS10455	COG2183	response to ionizing radiation
DWB87_RS10460	COG1191	sigma factor activity
DWB87_RS10470	COG1366	Belongs to the anti-sigma-factor antagonist family
DWB87_RS10475	COG2208	phosphoserine phosphatase activity
DWB87_RS10505	COG3428	Bacterial PH domain
DWB87_RS10535	COG2205	protein histidine kinase activity
DWB87_RS10540	COG0745	RESPONSE REGULATOR receiver
DWB87_RS10550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DWB87_RS10560	COG0772	Belongs to the SEDS family
DWB87_RS10575	COG1937	Protein conserved in bacteria
DWB87_RS10585	COG1418	mRNA catabolic process
DWB87_RS10630	COG0629	single-stranded DNA binding
DWB87_RS10705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DWB87_RS10730	COG0009	L-threonylcarbamoyladenylate synthase
DWB87_RS10735	COG2890	protein-(glutamine-N5) methyltransferase activity
DWB87_RS10760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DWB87_RS10800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DWB87_RS10845	COG0813	purine-nucleoside phosphorylase activity
DWB87_RS10850	COG0783	Belongs to the Dps family
DWB87_RS10870	COG1482	cell wall glycoprotein biosynthetic process
DWB87_RS10875	COG0702	epimerase
DWB87_RS10880	COG0640	Transcriptional regulator
DWB87_RS10915	COG0561	phosphatase activity
DWB87_RS10920	COG1119	ATPase activity
DWB87_RS10935	COG3711	transcriptional antiterminator
DWB87_RS10965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DWB87_RS11025	COG0489	protein tyrosine kinase activity
DWB87_RS11030	COG2814	Major facilitator Superfamily
DWB87_RS11045	COG1272	protein, Hemolysin III
DWB87_RS11055	COG1988	membrane-bound metal-dependent
DWB87_RS11065	COG3314	Sporulation integral membrane protein YlbJ
DWB87_RS11070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB87_RS11075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DWB87_RS11080	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DWB87_RS11090	COG3457	Alanine racemase
DWB87_RS11095	COG4264	IucA IucC family
DWB87_RS11100	COG2814	Major facilitator Superfamily
DWB87_RS11125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DWB87_RS11135	COG2130	NADP-dependent
DWB87_RS11200	COG0656	L-ascorbic acid biosynthetic process
DWB87_RS11205	COG0789	Transcriptional regulator
DWB87_RS11215	COG5492	domain, Protein
DWB87_RS11225	COG3527	Alpha-acetolactate decarboxylase
DWB87_RS11230	COG0028	Belongs to the TPP enzyme family
DWB87_RS11305	COG0201	protein transport
DWB87_RS11420	COG2252	PERMEase
DWB87_RS11465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DWB87_RS11525	COG1763	Mo-molybdopterin cofactor biosynthetic process
DWB87_RS11545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DWB87_RS11550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DWB87_RS11555	COG4149	molybdate abc transporter
DWB87_RS11560	COG0725	ABC transporter, periplasmic molybdate-binding protein
DWB87_RS11575	COG1268	BioY protein
DWB87_RS11590	COG1960	acyl-CoA dehydrogenase activity
DWB87_RS11595	COG4413	Urea transporter
DWB87_RS11665	COG1757	Na H antiporter
DWB87_RS11680	COG3942	CHAP domain
DWB87_RS11755	COG1113	amino acid transport
DWB87_RS11775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DWB87_RS11780	COG0385	Bile acid
DWB87_RS11790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB87_RS11790	COG1263	PTS System
DWB87_RS11795	COG1737	Transcriptional regulator
DWB87_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
DWB87_RS11820	COG1473	amidohydrolase
DWB87_RS11835	COG0583	DNA-binding transcription factor activity
DWB87_RS11855	COG2258	MOSC domain
DWB87_RS11875	COG1668	transmembrane transport
DWB87_RS11880	COG4152	abc transporter atp-binding protein
DWB87_RS11885	COG3152	Membrane
DWB87_RS11900	COG0786	glutamate:sodium symporter activity
DWB87_RS11910	COG0598	Magnesium transport protein CorA
DWB87_RS11925	COG0657	acetylesterase activity
DWB87_RS11935	COG2814	Major facilitator Superfamily
DWB87_RS11940	COG1566	PFAM secretion protein HlyD family protein
DWB87_RS11950	COG2814	Major facilitator Superfamily
DWB87_RS12010	COG1620	l-lactate permease
DWB87_RS12030	COG0604	alcohol dehydrogenase
DWB87_RS12060	COG1511	domain protein
DWB87_RS12075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWB87_RS12075	COG1263	PTS System
DWB87_RS12090	COG3871	stress protein (general stress protein 26)
DWB87_RS12130	COG0789	Transcriptional regulator
DWB87_RS12150	COG2181	nitrate reductase activity
DWB87_RS12160	COG1140	nitrate reductase beta subunit
DWB87_RS12175	COG2146	nitrite reductase [NAD(P)H] activity
DWB87_RS12180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DWB87_RS12190	COG0454	-acetyltransferase
DWB87_RS12195	COG2116	formate transmembrane transporter activity
DWB87_RS12210	COG3443	Belongs to the bacterial solute-binding protein 9 family
DWB87_RS12210	COG0803	Belongs to the bacterial solute-binding protein 9 family
DWB87_RS12245	COG1126	abc transporter atp-binding protein
DWB87_RS12250	COG0765	amino acid transport
DWB87_RS12255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DWB87_RS12260	COG2814	Major facilitator Superfamily
DWB87_RS12275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DWB87_RS12320	COG0156	8-amino-7-oxononanoate synthase activity
DWB87_RS12330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DWB87_RS12335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DWB87_RS12345	COG1132	(ABC) transporter
DWB87_RS12350	COG2375	cellular response to nickel ion
DWB87_RS12350	COG1132	(ABC) transporter
DWB87_RS12365	COG1929	Belongs to the glycerate kinase type-1 family
DWB87_RS12375	COG2814	Major facilitator Superfamily
DWB87_RS12395	COG1113	amino acid transport
DWB87_RS12405	COG0531	amino acid
DWB87_RS12420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DWB87_RS12430	COG1174	glycine betaine transport
DWB87_RS12440	COG1174	glycine betaine transport
DWB87_RS12460	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DWB87_RS12465	COG0531	amino acid
DWB87_RS12470	COG2272	Belongs to the type-B carboxylesterase lipase family
DWB87_RS12475	COG2814	Major facilitator Superfamily
DWB87_RS12480	COG0390	transport system, permease component
DWB87_RS12485	COG4619	ABC transporter
DWB87_RS12490	COG1363	Peptidase, m42
DWB87_RS12510	COG4808	Protein conserved in bacteria
DWB87_RS12515	COG0069	glutamate synthase activity
DWB87_RS12530	COG1124	(ABC) transporter
DWB87_RS12535	COG0444	Belongs to the ABC transporter superfamily
DWB87_RS12540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DWB87_RS12575	COG1028	Short-chain dehydrogenase reductase Sdr
DWB87_RS12580	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DWB87_RS12585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DWB87_RS12660	COG0494	nUDIX hydrolase
DWB87_RS12705	COG1846	Transcriptional regulator
DWB87_RS12740	COG1070	Carbohydrate kinase
DWB87_RS12745	COG1802	Transcriptional regulator
DWB87_RS12750	COG0789	Transcriptional regulator
DWB87_RS12755	COG2357	RelA SpoT domain protein
DWB87_RS12760	COG4876	unkown
DWB87_RS12775	COG2271	Major facilitator Superfamily
DWB87_RS12780	COG0586	Pfam SNARE associated Golgi protein
DWB87_RS12795	COG1131	(ABC) transporter
DWB87_RS12815	COG0400	carboxylic ester hydrolase activity
DWB87_RS12820	COG0346	lactoylglutathione lyase activity
DWB87_RS12825	COG1846	Transcriptional regulator
DWB87_RS12835	COG2514	catechol 2,3-dioxygenase activity
DWB87_RS12850	COG0561	phosphatase activity
DWB87_RS12855	COG1131	(ABC) transporter
DWB87_RS12865	COG3764	Sortase (surface protein transpeptidase)
DWB87_RS12885	COG1760	l-serine dehydratase
DWB87_RS12890	COG1760	l-serine dehydratase
DWB87_RS12905	COG0697	spore germination
DWB87_RS12910	COG0657	acetylesterase activity
DWB87_RS12930	COG0028	Belongs to the TPP enzyme family
DWB87_RS12945	COG0583	DNA-binding transcription factor activity
DWB87_RS12955	COG3942	CHAP domain
DWB87_RS12965	COG3425	synthase
DWB87_RS12970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DWB87_RS12995	COG2409	Drug exporters of the RND superfamily
DWB87_RS13040	COG0436	Aminotransferase
DWB87_RS13070	COG3942	CHAP domain
DWB87_RS13075	COG2755	lipolytic protein G-D-S-L family
DWB87_RS13075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DWB87_RS13185	COG3001	Fructosamine kinase
DWB87_RS13190	COG0167	dihydroorotate dehydrogenase activity
DWB87_RS13240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DWB87_RS13245	COG3527	Alpha-acetolactate decarboxylase
DWB87_RS13255	COG0531	amino acid
DWB87_RS13285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DWB87_RS13305	COG1012	belongs to the aldehyde dehydrogenase family
DWB87_RS13315	COG1510	regulation of RNA biosynthetic process
DWB87_RS13325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DWB87_RS13350	COG2851	Citrate transporter
DWB87_RS13360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DWB87_RS13370	COG0386	Belongs to the glutathione peroxidase family
DWB87_RS13395	COG1136	(ABC) transporter
DWB87_RS13400	COG2205	protein histidine kinase activity
DWB87_RS13405	COG0745	RESPONSE REGULATOR receiver
DWB87_RS13415	COG1785	Belongs to the alkaline phosphatase family
DWB87_RS13425	COG1846	Transcriptional regulator
DWB87_RS13470	COG1438	arginine binding
DWB87_RS13490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB87_RS13490	COG3711	transcriptional antiterminator
DWB87_RS13495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWB87_RS13495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWB87_RS13495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWB87_RS13500	COG1482	cell wall glycoprotein biosynthetic process
DWB87_RS13510	COG3942	CHAP domain
DWB87_RS13510	COG1705	Flagellar rod assembly protein muramidase FlgJ
DWB87_RS13515	COG1535	isochorismatase
DWB87_RS13515	COG3433	isochorismatase activity
DWB87_RS13530	COG0438	transferase activity, transferring glycosyl groups
DWB87_RS13545	COG1073	alpha beta
DWB87_RS13565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DWB87_RS13585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DWB87_RS13640	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DWB87_RS13675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DWB87_RS13755	COG0471	metal ion transport
DWB87_RS13760	COG2962	Rard protein
DWB87_RS13770	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DWB87_RS13785	COG1136	(ABC) transporter
DWB87_RS13790	COG0577	efflux transmembrane transporter activity
DWB87_RS13800	COG1278	Cold shock
DWB87_RS13820	COG1475	DNA binding