locus-tag	class	description
A7U44_RS00045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A7U44_RS00050	COG0527	aspartate kinase activity
A7U44_RS00055	COG0488	(ABC) transporter
A7U44_RS00070	COG0573	inorganic phosphate transmembrane transporter activity
A7U44_RS00075	COG0581	inorganic phosphate transmembrane transporter activity
A7U44_RS00085	COG0704	Plays a role in the regulation of phosphate uptake
A7U44_RS00130	COG0561	phosphatase activity
A7U44_RS00170	COG0512	Glutamine amidotransferase of anthranilate synthase
A7U44_RS00175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7U44_RS00180	COG1363	Peptidase, m42
A7U44_RS00190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A7U44_RS00215	COG0628	permease
A7U44_RS00230	COG1115	amino acid carrier protein
A7U44_RS00240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7U44_RS00270	COG0824	Thioesterase
A7U44_RS00285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U44_RS00305	COG4846	Membrane protein involved in cytochrome C biogenesis
A7U44_RS00340	COG2340	Cysteine-rich secretory protein family
A7U44_RS00370	COG0833	amino acid
A7U44_RS00395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7U44_RS00400	COG0460	homoserine dehydrogenase
A7U44_RS00405	COG0527	aspartate kinase activity
A7U44_RS00420	COG1525	nuclease
A7U44_RS00430	COG2197	response regulator
A7U44_RS00445	COG1131	(ABC) transporter
A7U44_RS00550	COG0789	Transcriptional regulator
A7U44_RS00555	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A7U44_RS00560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7U44_RS00570	COG1923	regulation of RNA biosynthetic process
A7U44_RS00595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A7U44_RS00600	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A7U44_RS00635	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7U44_RS00640	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7U44_RS00640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7U44_RS00645	COG1692	metallophosphoesterase
A7U44_RS00665	COG1058	Belongs to the CinA family
A7U44_RS00665	COG1546	Belongs to the CinA family
A7U44_RS00685	COG0300	oxidoreductase activity
A7U44_RS00690	COG0612	Peptidase, M16
A7U44_RS00695	COG0612	Peptidase, M16
A7U44_RS00700	COG2188	Transcriptional regulator
A7U44_RS00730	COG0196	riboflavin kinase activity
A7U44_RS00755	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A7U44_RS00760	COG0195	Participates in both transcription termination and antitermination
A7U44_RS00860	COG0758	DNA mediated transformation
A7U44_RS00865	COG2348	transferase activity, transferring amino-acyl groups
A7U44_RS00920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7U44_RS00930	COG0552	protein localization to endoplasmic reticulum
A7U44_RS00935	COG1196	nuclear chromosome segregation
A7U44_RS00985	COG1302	Protein conserved in bacteria
A7U44_RS01000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A7U44_RS01015	COG0631	protein serine/threonine phosphatase activity
A7U44_RS01025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7U44_RS01025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7U44_RS01050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A7U44_RS01055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A7U44_RS01070	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A7U44_RS01115	COG2233	PERMEase
A7U44_RS01125	COG0564	pseudouridine synthase activity
A7U44_RS01145	COG2514	catechol 2,3-dioxygenase activity
A7U44_RS01155	COG3599	regulation of cell shape
A7U44_RS01160	COG2302	S4 RNA-binding domain
A7U44_RS01165	COG0762	integral membrane protein
A7U44_RS01175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A7U44_RS01190	COG0849	cell division
A7U44_RS01195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A7U44_RS01210	COG0768	penicillin binding
A7U44_RS01215	COG4839	cell division protein FtsL
A7U44_RS01240	COG1011	Hydrolase
A7U44_RS01280	COG1288	antiporter activity
A7U44_RS01400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A7U44_RS01405	COG1053	succinate dehydrogenase
A7U44_RS01410	COG2009	succinate dehydrogenase
A7U44_RS01435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7U44_RS01435	COG1796	DNA polymerase
A7U44_RS01470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7U44_RS01485	COG4509	Sortase family
A7U44_RS01545	COG0742	ribosomal rna small subunit methyltransferase
A7U44_RS01565	COG3679	Belongs to the UPF0342 family
A7U44_RS01600	COG0772	Belongs to the SEDS family
A7U44_RS01610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A7U44_RS01620	COG1217	gtp-binding protein TYPA
A7U44_RS01630	COG0483	inositol monophosphate 1-phosphatase activity
A7U44_RS01655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A7U44_RS01660	COG1177	transmembrane transport
A7U44_RS01665	COG1176	ABC-type spermidine putrescine transport system, permease component I
A7U44_RS01730	COG0569	domain protein
A7U44_RS01735	COG1294	oxidase, subunit
A7U44_RS01740	COG1271	oxidase subunit
A7U44_RS01765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A7U44_RS01790	COG4721	ABC-type cobalt transport system, permease component
A7U44_RS01795	COG4172	Belongs to the ABC transporter superfamily
A7U44_RS01800	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7U44_RS01840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7U44_RS01855	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7U44_RS01900	COG1316	TRANSCRIPTIONal
A7U44_RS01940	COG3594	Acyltransferase
A7U44_RS01945	COG0436	Aminotransferase
A7U44_RS01970	COG2267	carboxylic ester hydrolase activity
A7U44_RS01980	COG1169	isochorismate synthase
A7U44_RS01990	COG1575	Belongs to the MenA family. Type 1 subfamily
A7U44_RS01995	COG0456	acetyltransferase
A7U44_RS02000	COG2314	TM2 domain
A7U44_RS02010	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7U44_RS02065	COG4873	Protein conserved in bacteria
A7U44_RS02080	COG4903	ComK protein
A7U44_RS02095	COG0737	Belongs to the 5'-nucleotidase family
A7U44_RS02100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7U44_RS02110	COG0861	Integral membrane protein TerC family
A7U44_RS02160	COG1115	amino acid carrier protein
A7U44_RS02165	COG0628	permease
A7U44_RS02175	COG0569	domain protein
A7U44_RS02175	COG0475	glutathione-regulated potassium exporter activity
A7U44_RS02180	COG2239	Acts as a magnesium transporter
A7U44_RS02185	COG0564	pseudouridine synthase activity
A7U44_RS02195	COG2357	RelA SpoT domain protein
A7U44_RS02210	COG2346	COG2346, Truncated hemoglobins
A7U44_RS02220	COG1164	Oligoendopeptidase f
A7U44_RS02245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U44_RS02250	COG0601	transmembrane transport
A7U44_RS02255	COG4608	Belongs to the ABC transporter superfamily
A7U44_RS02260	COG0444	Belongs to the ABC transporter superfamily
A7U44_RS02265	COG0747	negative chemotaxis
A7U44_RS02270	COG4166	transmembrane transport
A7U44_RS02275	COG4608	Belongs to the ABC transporter superfamily
A7U44_RS02280	COG0444	Belongs to the ABC transporter superfamily
A7U44_RS02285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U44_RS02290	COG0601	transmembrane transport
A7U44_RS02320	COG1881	PFAM PEBP family protein
A7U44_RS02360	COG4974	Belongs to the 'phage' integrase family
A7U44_RS02405	COG0561	phosphatase activity
A7U44_RS02455	COG0398	Pfam SNARE associated Golgi protein
A7U44_RS02475	COG0584	glycerophosphoryl diester phosphodiesterase
A7U44_RS02490	COG1902	pentaerythritol trinitrate reductase activity
A7U44_RS02495	COG1098	S1 RNA binding domain
A7U44_RS02550	COG2050	protein possibly involved in aromatic compounds catabolism
A7U44_RS02555	COG2056	Na+-H+ antiporter family
A7U44_RS02560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A7U44_RS02570	COG0316	Belongs to the HesB IscA family
A7U44_RS02580	COG1252	NADH dehydrogenase
A7U44_RS02585	COG4837	Protein of unknown function (DUF1462)
A7U44_RS02590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A7U44_RS02595	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A7U44_RS02605	COG1696	Membrane protein involved in D-alanine export
A7U44_RS02635	COG2445	Protein of unknown function DUF86
A7U44_RS02645	COG4470	Protein conserved in bacteria
A7U44_RS02660	COG0730	response to heat
A7U44_RS02665	COG1801	Protein of unknown function DUF72
A7U44_RS02675	COG1253	flavin adenine dinucleotide binding
A7U44_RS02700	COG0822	iron-sulfur transferase activity
A7U44_RS02710	COG0719	Fe-S assembly protein
A7U44_RS02715	COG0396	ATPase activity
A7U44_RS02730	COG1464	Belongs to the NlpA lipoprotein family
A7U44_RS02735	COG2011	ABC-type metal ion transport system permease component
A7U44_RS02750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7U44_RS02760	COG3878	Protein conserved in bacteria
A7U44_RS02775	COG1393	Belongs to the ArsC family
A7U44_RS02780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7U44_RS02805	COG1279	arginine transmembrane transporter activity
A7U44_RS02810	COG0406	alpha-ribazole phosphatase activity
A7U44_RS02850	COG1278	Cold shock
A7U44_RS02910	COG0557	exoribonuclease II activity
A7U44_RS02915	COG1647	Serine aminopeptidase, S33
A7U44_RS02920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7U44_RS02985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A7U44_RS03045	COG1388	LysM domain
A7U44_RS03045	COG3942	CHAP domain
A7U44_RS03075	COG1040	competence protein
A7U44_RS03080	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A7U44_RS03090	COG1739	Uncharacterized protein family UPF0029
A7U44_RS03095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7U44_RS03150	COG4607	ABC-type enterochelin transport system periplasmic component
A7U44_RS03155	COG4604	ABC transporter, ATP-binding protein
A7U44_RS03160	COG4605	iron ion homeostasis
A7U44_RS03165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U44_RS03175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7U44_RS03180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7U44_RS03210	COG3104	oligopeptide transport
A7U44_RS03240	COG1174	glycine betaine transport
A7U44_RS03245	COG0517	IMP dehydrogenase activity
A7U44_RS03245	COG1125	glycine betaine transport
A7U44_RS03250	COG0514	ATP-dependent DNA helicase (RecQ)
A7U44_RS03255	COG0488	(ABC) transporter
A7U44_RS03285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7U44_RS03290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7U44_RS03290	COG0512	Glutamine amidotransferase of anthranilate synthase
A7U44_RS03300	COG0720	synthase
A7U44_RS03335	COG0463	Glycosyl transferase, family 2
A7U44_RS03340	COG0656	L-ascorbic acid biosynthetic process
A7U44_RS03345	COG1253	flavin adenine dinucleotide binding
A7U44_RS03350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A7U44_RS03355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U44_RS03355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U44_RS03355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U44_RS03360	COG1105	Belongs to the carbohydrate kinase PfkB family
A7U44_RS03365	COG1349	DNA-binding transcription factor activity
A7U44_RS03370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A7U44_RS03400	COG0415	Belongs to the DNA photolyase family
A7U44_RS03405	COG0471	metal ion transport
A7U44_RS03415	COG4989	oxidoreductase activity
A7U44_RS03420	COG0523	cobalamin synthesis protein
A7U44_RS03430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A7U44_RS03435	COG4988	ABC transporter
A7U44_RS03455	COG1611	Belongs to the LOG family
A7U44_RS03485	COG2839	Protein conserved in bacteria
A7U44_RS03490	COG2814	Major facilitator Superfamily
A7U44_RS03500	COG0583	DNA-binding transcription factor activity
A7U44_RS03530	COG1917	Cupin 2, conserved barrel domain protein
A7U44_RS03530	COG4977	sequence-specific DNA binding
A7U44_RS03540	COG1388	LysM domain
A7U44_RS03540	COG3942	CHAP domain
A7U44_RS03545	COG0306	phosphate transporter
A7U44_RS03550	COG1392	Phosphate transport regulator
A7U44_RS03555	COG0577	efflux transmembrane transporter activity
A7U44_RS03560	COG1136	(ABC) transporter
A7U44_RS03575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7U44_RS03600	COG3949	Membrane
A7U44_RS03610	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A7U44_RS03620	COG2376	Dihydroxyacetone kinase
A7U44_RS03625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U44_RS03630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U44_RS03635	COG1120	ATPase activity
A7U44_RS03640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7U44_RS03650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U44_RS03655	COG1132	(ABC) transporter
A7U44_RS03660	COG1686	Belongs to the peptidase S11 family
A7U44_RS03665	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A7U44_RS03675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U44_RS03680	COG1682	transport, permease protein
A7U44_RS03690	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A7U44_RS03700	COG1321	iron dependent repressor
A7U44_RS03705	COG1121	(ABC) transporter
A7U44_RS03710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7U44_RS03715	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7U44_RS03760	COG4974	Belongs to the 'phage' integrase family
A7U44_RS03810	COG4139	cobalamin transport
A7U44_RS03815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U44_RS03850	COG1078	dGTPase activity
A7U44_RS03860	COG0655	NAD(P)H dehydrogenase (quinone) activity
A7U44_RS03870	COG0667	Aldo Keto reductase
A7U44_RS03905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7U44_RS03925	COG0083	homoserine kinase activity
A7U44_RS03940	COG0095	Lipoate-protein ligase
A7U44_RS04055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7U44_RS04100	COG0561	phosphatase activity
A7U44_RS04110	COG1428	Deoxynucleoside kinase
A7U44_RS04115	COG1428	Deoxynucleoside kinase
A7U44_RS04120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A7U44_RS04155	COG1473	amidohydrolase
A7U44_RS04195	COG2813	Specifically methylates the guanine in position
A7U44_RS04255	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A7U44_RS04280	COG4956	integral membrane protein (PIN domain superfamily)
A7U44_RS04285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A7U44_RS04300	COG3880	PFAM UvrB UvrC protein
A7U44_RS04310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U44_RS04325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7U44_RS04420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7U44_RS04445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7U44_RS04460	COG1098	S1 RNA binding domain
A7U44_RS04470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A7U44_RS04475	COG3956	TIGRFAM MazG family protein
A7U44_RS04480	COG2244	polysaccharide biosynthetic process
A7U44_RS04525	COG0251	oxidation-reduction process
A7U44_RS04530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7U44_RS04540	COG4466	Protein conserved in bacteria
A7U44_RS04550	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7U44_RS04555	COG0084	hydrolase, TatD family'
A7U44_RS04565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A7U44_RS04575	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A7U44_RS04585	COG1774	PSP1 C-terminal conserved region
A7U44_RS04590	COG0470	DNA polymerase III
A7U44_RS04595	COG3870	Protein conserved in bacteria
A7U44_RS04605	COG1982	Orn Lys Arg decarboxylase major
A7U44_RS04645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A7U44_RS04665	COG2188	Transcriptional regulator
A7U44_RS04670	COG0366	Alpha amylase catalytic
A7U44_RS04675	COG1263	PTS System
A7U44_RS04675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U44_RS04685	COG0493	'glutamate synthase
A7U44_RS04695	COG2826	transposase and inactivated derivatives, IS30 family
A7U44_RS04725	COG1674	ftsk spoiiie
A7U44_RS04730	COG0433	COG0433 Predicted ATPase
A7U44_RS04750	COG2946	Replication initiation factor
A7U44_RS04775	COG0583	DNA-binding transcription factor activity
A7U44_RS04810	COG1464	Belongs to the NlpA lipoprotein family
A7U44_RS04815	COG2011	ABC-type metal ion transport system permease component
A7U44_RS04825	COG0626	cystathionine gamma-synthase activity
A7U44_RS04830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7U44_RS04835	COG0733	neurotransmitter:sodium symporter activity
A7U44_RS04845	COG1647	Serine aminopeptidase, S33
A7U44_RS04860	COG5609	conserved protein (DUF2294)
A7U44_RS04870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7U44_RS04895	COG0523	cobalamin synthesis protein
A7U44_RS05045	COG3759	membrane
A7U44_RS05135	COG2233	PERMEase
A7U44_RS05170	COG1823	symporter activity
A7U44_RS05275	COG0012	GTP binding
A7U44_RS05280	COG4481	Protein conserved in bacteria
A7U44_RS05285	COG0668	transmembrane transport
A7U44_RS05290	COG1475	DNA binding
A7U44_RS05300	COG0626	cystathionine gamma-synthase activity
A7U44_RS05310	COG0646	methionine synthase
A7U44_RS05310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A7U44_RS05340	COG1131	(ABC) transporter
A7U44_RS05350	COG1476	TRANSCRIPTIONal
A7U44_RS05360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7U44_RS05365	COG0805	protein transport
A7U44_RS05370	COG0672	)-iron permease
A7U44_RS05380	COG2822	iron ion transport
A7U44_RS05385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7U44_RS05400	COG0431	NADPH-dependent FMN reductase
A7U44_RS05405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U44_RS05410	COG0346	lactoylglutathione lyase activity
A7U44_RS05415	COG2271	Major facilitator Superfamily
A7U44_RS05440	COG3711	transcriptional antiterminator
A7U44_RS05445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U44_RS05455	COG3037	sugar-specific permease SgaT UlaA
A7U44_RS05485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U44_RS05510	COG3314	Sporulation integral membrane protein YlbJ
A7U44_RS05535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7U44_RS05540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U44_RS05570	COG0577	efflux transmembrane transporter activity
A7U44_RS05580	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A7U44_RS05590	COG1114	Component of the transport system for branched-chain amino acids
A7U44_RS05765	COG3942	CHAP domain
A7U44_RS05765	COG1388	LysM domain
A7U44_RS05800	COG1131	(ABC) transporter
A7U44_RS05855	COG2226	methyltransferase
A7U44_RS05860	COG2723	6-phospho-beta-galactosidase activity
A7U44_RS05865	COG2190	(PTS) system
A7U44_RS05865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U44_RS05865	COG1263	PTS System
A7U44_RS05875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7U44_RS05910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U44_RS05915	COG1063	alcohol dehydrogenase
A7U44_RS05925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U44_RS05935	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U44_RS05940	COG1063	alcohol dehydrogenase
A7U44_RS05950	COG1063	alcohol dehydrogenase
A7U44_RS05960	COG1063	alcohol dehydrogenase
A7U44_RS05965	COG3775	system Galactitol-specific IIC component
A7U44_RS05970	COG3414	Phosphotransferase system galactitol-specific IIB component
A7U44_RS05990	COG1957	nucleoside hydrolase
A7U44_RS05995	COG2190	(PTS) system
A7U44_RS05995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U44_RS05995	COG1263	PTS System
A7U44_RS06025	COG3189	MarR family transcriptional regulator
A7U44_RS06030	COG0747	negative chemotaxis
A7U44_RS06045	COG0318	PFAM AMP-dependent synthetase and ligase
A7U44_RS06050	COG1960	acyl-CoA dehydrogenase activity
A7U44_RS06060	COG0183	Belongs to the thiolase family
A7U44_RS06120	COG1755	Isoprenylcysteine carboxyl methyltransferase
A7U44_RS06130	COG0673	inositol 2-dehydrogenase activity
A7U44_RS06135	COG0673	inositol 2-dehydrogenase activity
A7U44_RS06140	COG3833	ABC-type maltose transport systems, permease component
A7U44_RS06145	COG1175	transmembrane transport
A7U44_RS06155	COG3842	ATPase activity
A7U44_RS06175	COG0405	Gamma-glutamyltransferase
A7U44_RS06185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U44_RS06190	COG0601	transmembrane transport
A7U44_RS06225	COG1737	Transcriptional regulator
A7U44_RS06255	COG3961	Belongs to the TPP enzyme family
A7U44_RS06260	COG1335	isochorismatase
A7U44_RS06265	COG1114	Component of the transport system for branched-chain amino acids
A7U44_RS06315	COG5609	conserved protein (DUF2294)
A7U44_RS06320	COG1960	acyl-CoA dehydrogenase activity
A7U44_RS06325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7U44_RS06360	COG2832	Protein of unknown function (DUF454)
A7U44_RS06370	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U44_RS06375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A7U44_RS06385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7U44_RS06415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U44_RS06425	COG1086	Polysaccharide biosynthesis protein
A7U44_RS06450	COG1012	belongs to the aldehyde dehydrogenase family
A7U44_RS06450	COG1454	alcohol dehydrogenase
A7U44_RS06495	COG0737	Belongs to the 5'-nucleotidase family
A7U44_RS06515	COG3639	organic phosphonate transmembrane transporter activity
A7U44_RS06535	COG2814	Major facilitator Superfamily
A7U44_RS06540	COG0813	purine-nucleoside phosphorylase activity
A7U44_RS06575	COG0438	transferase activity, transferring glycosyl groups
A7U44_RS06580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7U44_RS06585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7U44_RS06615	COG1475	DNA binding
A7U44_RS06620	COG0019	diaminopimelate decarboxylase activity
A7U44_RS06630	COG4264	IucA IucC family
A7U44_RS06635	COG4264	IucA IucC family
A7U44_RS06640	COG2814	Major facilitator Superfamily
A7U44_RS06645	COG4264	IucA IucC family
A7U44_RS06650	COG2423	ornithine cyclodeaminase activity
A7U44_RS06660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U44_RS06665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U44_RS06670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U44_RS06685	COG1388	LysM domain
A7U44_RS06690	COG1620	l-lactate permease
A7U44_RS06705	COG0697	spore germination
A7U44_RS06710	COG4716	Myosin-crossreactive antigen
A7U44_RS06715	COG1283	sodium-dependent phosphate transmembrane transporter activity
A7U44_RS06730	COG1473	amidohydrolase
A7U44_RS06750	COG0823	Involved in the tonB-independent uptake of proteins
A7U44_RS06760	COG2226	methyltransferase
A7U44_RS06775	COG1073	alpha beta
A7U44_RS06825	COG0737	Belongs to the 5'-nucleotidase family
A7U44_RS06830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A7U44_RS06840	COG4863	YycH protein
A7U44_RS06875	COG0305	Participates in initiation and elongation during chromosome replication
A7U44_RS06885	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A7U44_RS06895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A7U44_RS06925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A7U44_RS06945	COG2501	S4 domain
A7U44_RS06985	COG1475	DNA binding
A7U44_RS07010	COG1278	Cold shock
A7U44_RS07020	COG0577	efflux transmembrane transporter activity
A7U44_RS07025	COG1136	(ABC) transporter
A7U44_RS07040	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A7U44_RS07050	COG2962	Rard protein
A7U44_RS07055	COG0471	metal ion transport
A7U44_RS07130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7U44_RS07160	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A7U44_RS07215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7U44_RS07235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7U44_RS07255	COG1073	alpha beta
A7U44_RS07270	COG0438	transferase activity, transferring glycosyl groups
A7U44_RS07285	COG3433	isochorismatase activity
A7U44_RS07285	COG1535	isochorismatase
A7U44_RS07290	COG1705	Flagellar rod assembly protein muramidase FlgJ
A7U44_RS07290	COG3942	CHAP domain
A7U44_RS07300	COG1482	cell wall glycoprotein biosynthetic process
A7U44_RS07305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U44_RS07305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U44_RS07305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U44_RS07310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U44_RS07310	COG3711	transcriptional antiterminator
A7U44_RS07330	COG1438	arginine binding
A7U44_RS07375	COG1846	Transcriptional regulator
A7U44_RS07385	COG1785	Belongs to the alkaline phosphatase family
A7U44_RS07395	COG0745	RESPONSE REGULATOR receiver
A7U44_RS07400	COG2205	protein histidine kinase activity
A7U44_RS07405	COG1136	(ABC) transporter
A7U44_RS07430	COG0386	Belongs to the glutathione peroxidase family
A7U44_RS07440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A7U44_RS07455	COG2851	Citrate transporter
A7U44_RS07480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U44_RS07485	COG1510	regulation of RNA biosynthetic process
A7U44_RS07495	COG1012	belongs to the aldehyde dehydrogenase family
A7U44_RS07515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7U44_RS07545	COG0531	amino acid
A7U44_RS07555	COG3527	Alpha-acetolactate decarboxylase
A7U44_RS07560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7U44_RS07615	COG0167	dihydroorotate dehydrogenase activity
A7U44_RS07620	COG3001	Fructosamine kinase
A7U44_RS07660	COG0596	Alpha beta hydrolase
A7U44_RS07730	COG2755	lipolytic protein G-D-S-L family
A7U44_RS07730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A7U44_RS07735	COG3942	CHAP domain
A7U44_RS07765	COG0436	Aminotransferase
A7U44_RS07810	COG2409	Drug exporters of the RND superfamily
A7U44_RS07835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7U44_RS07840	COG3425	synthase
A7U44_RS07850	COG3942	CHAP domain
A7U44_RS07860	COG0583	DNA-binding transcription factor activity
A7U44_RS07875	COG0028	Belongs to the TPP enzyme family
A7U44_RS07895	COG0657	acetylesterase activity
A7U44_RS07900	COG0697	spore germination
A7U44_RS07915	COG1760	l-serine dehydratase
A7U44_RS07920	COG1760	l-serine dehydratase
A7U44_RS07940	COG3764	Sortase (surface protein transpeptidase)
A7U44_RS07950	COG1131	(ABC) transporter
A7U44_RS07955	COG0561	phosphatase activity
A7U44_RS07970	COG2514	catechol 2,3-dioxygenase activity
A7U44_RS07980	COG1846	Transcriptional regulator
A7U44_RS07985	COG0346	lactoylglutathione lyase activity
A7U44_RS07990	COG0400	carboxylic ester hydrolase activity
A7U44_RS07995	COG3949	Membrane
A7U44_RS08010	COG1131	(ABC) transporter
A7U44_RS08025	COG0586	Pfam SNARE associated Golgi protein
A7U44_RS08030	COG2271	Major facilitator Superfamily
A7U44_RS08045	COG4876	unkown
A7U44_RS08050	COG2357	RelA SpoT domain protein
A7U44_RS08055	COG0789	Transcriptional regulator
A7U44_RS08060	COG1802	Transcriptional regulator
A7U44_RS08065	COG1070	Carbohydrate kinase
A7U44_RS08100	COG1846	Transcriptional regulator
A7U44_RS08140	COG0494	nUDIX hydrolase
A7U44_RS08205	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7U44_RS08210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A7U44_RS08215	COG1028	Short-chain dehydrogenase reductase Sdr
A7U44_RS08260	COG1124	(ABC) transporter
A7U44_RS08275	COG0069	glutamate synthase activity
A7U44_RS08280	COG4808	Protein conserved in bacteria
A7U44_RS08300	COG1363	Peptidase, m42
A7U44_RS08305	COG4619	ABC transporter
A7U44_RS08310	COG0390	transport system, permease component
A7U44_RS08315	COG2814	Major facilitator Superfamily
A7U44_RS08320	COG2272	Belongs to the type-B carboxylesterase lipase family
A7U44_RS08325	COG0531	amino acid
A7U44_RS08335	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
A7U44_RS08365	COG1174	glycine betaine transport
A7U44_RS08375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7U44_RS08400	COG0531	amino acid
A7U44_RS08415	COG1113	amino acid transport
A7U44_RS08435	COG2814	Major facilitator Superfamily
A7U44_RS08445	COG1929	Belongs to the glycerate kinase type-1 family
A7U44_RS08465	COG2375	cellular response to nickel ion
A7U44_RS08465	COG1132	(ABC) transporter
A7U44_RS08470	COG1132	(ABC) transporter
A7U44_RS08485	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A7U44_RS08490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7U44_RS08500	COG0156	8-amino-7-oxononanoate synthase activity
A7U44_RS08550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7U44_RS08570	COG2814	Major facilitator Superfamily
A7U44_RS08575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7U44_RS08580	COG0765	amino acid transport
A7U44_RS08585	COG1126	abc transporter atp-binding protein
A7U44_RS08620	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7U44_RS08620	COG3443	Belongs to the bacterial solute-binding protein 9 family
A7U44_RS08635	COG2116	formate transmembrane transporter activity
A7U44_RS08640	COG0454	-acetyltransferase
A7U44_RS08650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7U44_RS08655	COG2146	nitrite reductase [NAD(P)H] activity
A7U44_RS08665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A7U44_RS08670	COG1140	nitrate reductase beta subunit
A7U44_RS08680	COG2181	nitrate reductase activity
A7U44_RS08730	COG3871	stress protein (general stress protein 26)
A7U44_RS08745	COG1263	PTS System
A7U44_RS08745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U44_RS08760	COG1511	domain protein
A7U44_RS08785	COG0456	acetyltransferase
A7U44_RS08795	COG0604	alcohol dehydrogenase
A7U44_RS08815	COG1620	l-lactate permease
A7U44_RS08880	COG2814	Major facilitator Superfamily
A7U44_RS08890	COG1566	PFAM secretion protein HlyD family protein
A7U44_RS08895	COG2814	Major facilitator Superfamily
A7U44_RS08905	COG0657	acetylesterase activity
A7U44_RS08920	COG0598	Magnesium transport protein CorA
A7U44_RS08930	COG0786	glutamate:sodium symporter activity
A7U44_RS08950	COG3152	Membrane
A7U44_RS08955	COG4152	abc transporter atp-binding protein
A7U44_RS08960	COG1668	transmembrane transport
A7U44_RS08980	COG2258	MOSC domain
A7U44_RS09005	COG0583	DNA-binding transcription factor activity
A7U44_RS09020	COG1473	amidohydrolase
A7U44_RS09025	COG1028	Short-chain dehydrogenase reductase Sdr
A7U44_RS09045	COG1737	Transcriptional regulator
A7U44_RS09050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U44_RS09050	COG1263	PTS System
A7U44_RS09060	COG0385	Bile acid
A7U44_RS09065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7U44_RS09085	COG1113	amino acid transport
A7U44_RS09160	COG3942	CHAP domain
A7U44_RS09175	COG1757	Na H antiporter
A7U44_RS09250	COG4413	Urea transporter
A7U44_RS09255	COG1960	acyl-CoA dehydrogenase activity
A7U44_RS09270	COG1268	BioY protein
A7U44_RS09285	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7U44_RS09290	COG4149	molybdate abc transporter
A7U44_RS09295	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A7U44_RS09300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7U44_RS09320	COG1763	Mo-molybdopterin cofactor biosynthetic process
A7U44_RS09390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A7U44_RS09440	COG2252	PERMEase
A7U44_RS09555	COG0201	protein transport
A7U44_RS09645	COG0028	Belongs to the TPP enzyme family
A7U44_RS09650	COG3527	Alpha-acetolactate decarboxylase
A7U44_RS09660	COG5492	domain, Protein
A7U44_RS09670	COG0789	Transcriptional regulator
A7U44_RS09675	COG0656	L-ascorbic acid biosynthetic process
A7U44_RS09750	COG2130	NADP-dependent
A7U44_RS09760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U44_RS09785	COG2814	Major facilitator Superfamily
A7U44_RS09790	COG4264	IucA IucC family
A7U44_RS09795	COG3457	Alanine racemase
A7U44_RS09805	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7U44_RS09810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U44_RS09820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U44_RS09825	COG3314	Sporulation integral membrane protein YlbJ
A7U44_RS09835	COG1988	membrane-bound metal-dependent
A7U44_RS09845	COG1272	protein, Hemolysin III
A7U44_RS09860	COG2814	Major facilitator Superfamily
A7U44_RS09865	COG0489	protein tyrosine kinase activity
A7U44_RS09925	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A7U44_RS09955	COG3711	transcriptional antiterminator
A7U44_RS09970	COG1119	ATPase activity
A7U44_RS09975	COG0561	phosphatase activity
A7U44_RS10010	COG0640	Transcriptional regulator
A7U44_RS10015	COG0702	epimerase
A7U44_RS10020	COG1482	cell wall glycoprotein biosynthetic process
A7U44_RS10040	COG0783	Belongs to the Dps family
A7U44_RS10045	COG0813	purine-nucleoside phosphorylase activity
A7U44_RS10095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7U44_RS10145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A7U44_RS10170	COG2890	protein-(glutamine-N5) methyltransferase activity
A7U44_RS10175	COG0009	L-threonylcarbamoyladenylate synthase
A7U44_RS10200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U44_RS10275	COG0629	single-stranded DNA binding
A7U44_RS10315	COG1418	mRNA catabolic process
A7U44_RS10325	COG1937	Protein conserved in bacteria
A7U44_RS10340	COG0772	Belongs to the SEDS family
A7U44_RS10350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A7U44_RS10360	COG0745	RESPONSE REGULATOR receiver
A7U44_RS10365	COG2205	protein histidine kinase activity
A7U44_RS10395	COG3428	Bacterial PH domain
A7U44_RS10430	COG2208	phosphoserine phosphatase activity
A7U44_RS10435	COG1366	Belongs to the anti-sigma-factor antagonist family
A7U44_RS10445	COG1191	sigma factor activity
A7U44_RS10450	COG2183	response to ionizing radiation
A7U44_RS10530	COG0028	Belongs to the TPP enzyme family
A7U44_RS10545	COG0802	atpase or kinase
A7U44_RS10550	COG1214	PFAM Peptidase M22, glycoprotease
A7U44_RS10555	COG0456	acetyltransferase
A7U44_RS10565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A7U44_RS10575	COG0488	(ABC) transporter
A7U44_RS10585	COG2391	methyltransferase activity
A7U44_RS10590	COG0425	Belongs to the sulfur carrier protein TusA family
A7U44_RS10595	COG0004	ammonium transporteR
A7U44_RS10600	COG1609	Transcriptional regulator
A7U44_RS10605	COG1621	beta-fructofuranosidase activity
A7U44_RS10610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7U44_RS10675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7U44_RS10680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U44_RS10685	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7U44_RS10735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7U44_RS10890	COG0740	serine-type endopeptidase activity
A7U44_RS10940	COG0739	heme binding
A7U44_RS10985	COG1388	LysM domain
A7U44_RS10985	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7U44_RS11060	COG1725	Transcriptional regulator
A7U44_RS11075	COG1131	(ABC) transporter
A7U44_RS11125	COG4974	Belongs to the 'phage' integrase family
A7U44_RS11155	COG3682	Transcriptional regulator
A7U44_RS11165	COG1012	belongs to the aldehyde dehydrogenase family
A7U44_RS11180	COG1335	isochorismatase
A7U44_RS11200	COG0077	Prephenate dehydratase
A7U44_RS11210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A7U44_RS11245	COG4496	protein, YerC YecD
A7U44_RS11255	COG0210	DNA helicase
A7U44_RS11265	COG4851	CamS sex pheromone cAM373 precursor
A7U44_RS11390	COG2197	response regulator
A7U44_RS11395	COG1295	ribonuclease BN
A7U44_RS11415	COG2309	aminopeptidase activity
A7U44_RS11420	COG1607	acyl-coa hydrolase
A7U44_RS11425	COG0535	radical SAM domain protein
A7U44_RS11455	COG1388	LysM domain
A7U44_RS11455	COG1134	teichoic acid transport
A7U44_RS11470	COG1988	membrane-bound metal-dependent
A7U44_RS11495	COG4129	membrane
A7U44_RS11505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7U44_RS11510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7U44_RS11675	COG0765	amino acid transport
A7U44_RS11680	COG1126	abc transporter atp-binding protein
A7U44_RS11685	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A7U44_RS11725	COG0564	pseudouridine synthase activity
A7U44_RS11730	COG4585	Histidine kinase
A7U44_RS11730	COG2203	Gaf domain
A7U44_RS11735	COG2197	response regulator
A7U44_RS11765	COG0420	3'-5' exonuclease activity
A7U44_RS11800	COG0537	adenosine 5'-monophosphoramidase activity
A7U44_RS11805	COG1131	(ABC) transporter
A7U44_RS11835	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7U44_RS12135	COG1506	peptidase
A7U44_RS12155	COG0656	L-ascorbic acid biosynthetic process
A7U44_RS12180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A7U44_RS12210	COG4193	domain, Protein
A7U44_RS12210	COG3266	domain, Protein
A7U44_RS12210	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7U44_RS12230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7U44_RS12230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7U44_RS12265	COG2267	carboxylic ester hydrolase activity
A7U44_RS12280	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A7U44_RS12285	COG1242	4 iron, 4 sulfur cluster binding
A7U44_RS12290	COG2814	Major facilitator Superfamily
A7U44_RS12310	COG2081	HI0933 family
A7U44_RS12315	COG2244	polysaccharide biosynthetic process
A7U44_RS12320	COG1187	pseudouridine synthase activity
A7U44_RS12340	COG0510	thiamine kinase activity
A7U44_RS12350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7U44_RS12360	COG1363	Peptidase, m42
A7U44_RS12365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7U44_RS12375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7U44_RS12380	COG1674	ftsk spoiiie
A7U44_RS12405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A7U44_RS12405	COG1605	Chorismate mutase
A7U44_RS12425	COG0454	-acetyltransferase
A7U44_RS12430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7U44_RS12435	COG2759	Belongs to the formate--tetrahydrofolate ligase family
A7U44_RS12465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7U44_RS12470	COG0204	Acyl-transferase
A7U44_RS12475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U44_RS12475	COG1263	PTS System
A7U44_RS12490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7U44_RS12495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7U44_RS12500	COG1764	response to oxidative stress
A7U44_RS12505	COG0584	glycerophosphoryl diester phosphodiesterase
A7U44_RS12525	COG1956	GAF domain-containing protein
A7U44_RS12530	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A7U44_RS12540	COG1104	cysteine desulfurase activity
A7U44_RS12560	COG0827	DNA restriction-modification system
A7U44_RS12600	COG4109	DRTGG domain
A7U44_RS12610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A7U44_RS12620	COG0281	malic enzyme
A7U44_RS12645	COG1113	amino acid transport
A7U44_RS12650	COG0372	Belongs to the citrate synthase family
A7U44_RS12665	COG0745	RESPONSE REGULATOR receiver
A7U44_RS12670	COG5002	protein histidine kinase activity
A7U44_RS12680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U44_RS12680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U44_RS12710	COG1484	DNA-dependent DNA replication
A7U44_RS12725	COG0833	amino acid
A7U44_RS12750	COG4112	unkown
A7U44_RS12785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7U44_RS12820	COG2818	Glycosylase
A7U44_RS12830	COG0285	dihydrofolate synthase activity
A7U44_RS12840	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A7U44_RS12885	COG2868	ribosomal protein
A7U44_RS12925	COG1862	Preprotein translocase
A7U44_RS12930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7U44_RS12930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7U44_RS12935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A7U44_RS12935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A7U44_RS12980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A7U44_RS12985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7U44_RS12990	COG1959	2 iron, 2 sulfur cluster binding
A7U44_RS12995	COG3237	CsbD-like
A7U44_RS13005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U44_RS13010	COG1104	cysteine desulfurase activity
A7U44_RS13030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A7U44_RS13060	COG0826	peptidase U32
A7U44_RS13065	COG0826	peptidase U32
A7U44_RS13080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7U44_RS13085	COG1984	allophanate hydrolase subunit 2
A7U44_RS13090	COG0511	ligase activity, forming carbon-carbon bonds
A7U44_RS13095	COG0439	Biotin carboxylase
A7U44_RS13105	COG1914	H( )-stimulated, divalent metal cation uptake system
A7U44_RS13130	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A7U44_RS13135	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A7U44_RS13145	COG1534	Rna-binding protein
A7U44_RS13155	COG1713	HD superfamily hydrolase involved in NAD metabolism
A7U44_RS13160	COG0799	negative regulation of ribosome biogenesis
A7U44_RS13165	COG2226	methyltransferase
A7U44_RS13175	COG2131	deaminase
A7U44_RS13180	COG2333	competence protein COMEC
A7U44_RS13180	COG0658	competence protein
A7U44_RS13185	COG1466	dna polymerase III delta subunit
A7U44_RS13205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7U44_RS13235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A7U44_RS13240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7U44_RS13250	COG1030	water channel activity
A7U44_RS13265	COG1702	phosphate starvation-inducible protein PhoH
A7U44_RS13280	COG0295	cytidine deaminase activity
A7U44_RS13300	COG0517	IMP dehydrogenase activity
A7U44_RS13320	COG2384	SAM-dependent methyltransferase
A7U44_RS13330	COG0513	Belongs to the DEAD box helicase family
A7U44_RS13340	COG1121	(ABC) transporter
A7U44_RS13345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7U44_RS13360	COG0768	penicillin binding
A7U44_RS13370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A7U44_RS13380	COG4483	Protein conserved in bacteria
A7U44_RS13385	COG1940	carbohydrate kinase activity
A7U44_RS13390	COG0011	TIGRFAM Protein of
A7U44_RS13395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7U44_RS13400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A7U44_RS13405	COG1459	type II secretion system
A7U44_RS13410	COG4537	Required for transformation and DNA binding
A7U44_RS13455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7U44_RS13460	COG0095	Lipoate-protein ligase
A7U44_RS13475	COG0006	proline dipeptidase activity
A7U44_RS13485	COG0511	ligase activity, forming carbon-carbon bonds
A7U44_RS13490	COG0439	Biotin carboxylase
A7U44_RS13495	COG1302	Protein conserved in bacteria
A7U44_RS13525	COG0497	DNA recombination
A7U44_RS13530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7U44_RS13535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7U44_RS13540	COG0022	dehydrogenase e1 component
A7U44_RS13545	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7U44_RS13555	COG4129	membrane
A7U44_RS13565	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7U44_RS13585	COG1609	Transcriptional regulator
A7U44_RS13590	COG0366	Alpha amylase catalytic
A7U44_RS13600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A7U44_RS13615	COG4221	oxidoreductase activity
A7U44_RS13625	COG0667	Aldo Keto reductase
A7U44_RS13630	COG0494	nUDIX hydrolase
A7U44_RS13635	COG0735	belongs to the Fur family
A7U44_RS13660	COG1187	pseudouridine synthase activity
A7U44_RS13665	COG0745	RESPONSE REGULATOR receiver
A7U44_RS13670	COG5002	protein histidine kinase activity
A7U44_RS13705	COG1141	Ferredoxin
A7U44_RS13715	COG0514	ATP-dependent DNA helicase (RecQ)
A7U44_RS13730	COG0492	ferredoxin-NADP+ reductase activity
A7U44_RS13795	COG0142	geranyltranstransferase activity
A7U44_RS13835	COG4347	Protein of unknown function (DUF1405)
A7U44_RS13840	COG2738	Putative neutral zinc metallopeptidase
A7U44_RS13845	COG1694	Mazg nucleotide pyrophosphohydrolase
A7U44_RS13850	COG0438	transferase activity, transferring glycosyl groups
A7U44_RS13875	COG3935	DnaD domain protein
A7U44_RS13880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7U44_RS13890	COG4499	WXG100 protein secretion system (Wss), protein YukC
A7U44_RS13890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7U44_RS13925	COG0116	Belongs to the methyltransferase superfamily
A7U44_RS13940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7U44_RS13945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U44_RS13960	COG0531	amino acid
A7U44_RS13985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A7U44_RS14060	COG0671	phosphoesterase, PA-phosphatase related
A7U44_RS14105	COG0714	Associated with various cellular activities
A7U44_RS14110	COG4548	von Willebrand factor, type A