locus-tag	class	description
BXP64_RS00015	COG2501	S4 domain
BXP64_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BXP64_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXP64_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BXP64_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
BXP64_RS00125	COG4863	YycH protein
BXP64_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BXP64_RS00140	COG0737	Belongs to the 5'-nucleotidase family
BXP64_RS00205	COG2814	Major facilitator Superfamily
BXP64_RS00230	COG0456	acetyltransferase
BXP64_RS00255	COG0655	NAD(P)H dehydrogenase (quinone) activity
BXP64_RS00270	COG1073	alpha beta
BXP64_RS00280	COG2226	methyltransferase
BXP64_RS00290	COG0823	Involved in the tonB-independent uptake of proteins
BXP64_RS00305	COG1473	amidohydrolase
BXP64_RS00315	COG1283	sodium-dependent phosphate transmembrane transporter activity
BXP64_RS00320	COG4716	Myosin-crossreactive antigen
BXP64_RS00330	COG1620	l-lactate permease
BXP64_RS00350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXP64_RS00355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXP64_RS00360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BXP64_RS00370	COG2423	ornithine cyclodeaminase activity
BXP64_RS00375	COG4264	IucA IucC family
BXP64_RS00380	COG2814	Major facilitator Superfamily
BXP64_RS00385	COG4264	IucA IucC family
BXP64_RS00390	COG4264	IucA IucC family
BXP64_RS00400	COG0019	diaminopimelate decarboxylase activity
BXP64_RS00405	COG1475	DNA binding
BXP64_RS00435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXP64_RS00440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BXP64_RS00445	COG0438	transferase activity, transferring glycosyl groups
BXP64_RS00480	COG2814	Major facilitator Superfamily
BXP64_RS00500	COG3639	organic phosphonate transmembrane transporter activity
BXP64_RS00520	COG0737	Belongs to the 5'-nucleotidase family
BXP64_RS00535	COG1012	belongs to the aldehyde dehydrogenase family
BXP64_RS00535	COG1454	alcohol dehydrogenase
BXP64_RS00560	COG1086	Polysaccharide biosynthesis protein
BXP64_RS00570	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BXP64_RS00600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BXP64_RS00610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BXP64_RS00615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BXP64_RS00625	COG2832	Protein of unknown function (DUF454)
BXP64_RS00660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXP64_RS00665	COG1960	acyl-CoA dehydrogenase activity
BXP64_RS00670	COG5609	conserved protein (DUF2294)
BXP64_RS00725	COG1309	transcriptional regulator
BXP64_RS00730	COG1114	Component of the transport system for branched-chain amino acids
BXP64_RS00735	COG1335	isochorismatase
BXP64_RS00740	COG3961	Belongs to the TPP enzyme family
BXP64_RS00770	COG1737	Transcriptional regulator
BXP64_RS00795	COG0601	transmembrane transport
BXP64_RS00800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BXP64_RS00830	COG3842	ATPase activity
BXP64_RS00840	COG1175	transmembrane transport
BXP64_RS00845	COG3833	ABC-type maltose transport systems, permease component
BXP64_RS00850	COG0673	inositol 2-dehydrogenase activity
BXP64_RS00855	COG0673	inositol 2-dehydrogenase activity
BXP64_RS00865	COG1755	Isoprenylcysteine carboxyl methyltransferase
BXP64_RS00920	COG0183	Belongs to the thiolase family
BXP64_RS00930	COG1960	acyl-CoA dehydrogenase activity
BXP64_RS00935	COG0318	PFAM AMP-dependent synthetase and ligase
BXP64_RS00955	COG0747	negative chemotaxis
BXP64_RS00960	COG3189	MarR family transcriptional regulator
BXP64_RS00995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BXP64_RS00995	COG2190	(PTS) system
BXP64_RS00995	COG1263	PTS System
BXP64_RS01000	COG1957	nucleoside hydrolase
BXP64_RS01020	COG3414	Phosphotransferase system galactitol-specific IIB component
BXP64_RS01025	COG3775	system Galactitol-specific IIC component
BXP64_RS01030	COG1063	alcohol dehydrogenase
BXP64_RS01040	COG1063	alcohol dehydrogenase
BXP64_RS01050	COG1063	alcohol dehydrogenase
BXP64_RS01055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BXP64_RS01065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BXP64_RS01075	COG1063	alcohol dehydrogenase
BXP64_RS01080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BXP64_RS01120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXP64_RS01130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BXP64_RS01130	COG2190	(PTS) system
BXP64_RS01130	COG1263	PTS System
BXP64_RS01135	COG2723	6-phospho-beta-galactosidase activity
BXP64_RS01145	COG2226	methyltransferase
BXP64_RS01200	COG1131	(ABC) transporter
BXP64_RS01220	COG3942	CHAP domain
BXP64_RS01220	COG1388	LysM domain
BXP64_RS01330	COG1114	Component of the transport system for branched-chain amino acids
BXP64_RS01340	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BXP64_RS01350	COG0577	efflux transmembrane transporter activity
BXP64_RS01380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BXP64_RS01385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXP64_RS01410	COG3314	Sporulation integral membrane protein YlbJ
BXP64_RS01435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXP64_RS01465	COG3037	sugar-specific permease SgaT UlaA
BXP64_RS01475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXP64_RS01480	COG3711	transcriptional antiterminator
BXP64_RS01505	COG2271	Major facilitator Superfamily
BXP64_RS01510	COG0346	lactoylglutathione lyase activity
BXP64_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXP64_RS01520	COG0431	NADPH-dependent FMN reductase
BXP64_RS01540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXP64_RS01545	COG2822	iron ion transport
BXP64_RS01555	COG0672	)-iron permease
BXP64_RS01560	COG0805	protein transport
BXP64_RS01565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXP64_RS01575	COG1476	TRANSCRIPTIONal
BXP64_RS01585	COG1131	(ABC) transporter
BXP64_RS01615	COG0646	methionine synthase
BXP64_RS01615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BXP64_RS01620	COG0626	cystathionine gamma-synthase activity
BXP64_RS01625	COG0626	cystathionine gamma-synthase activity
BXP64_RS01635	COG1475	DNA binding
BXP64_RS01640	COG0668	transmembrane transport
BXP64_RS01645	COG4481	Protein conserved in bacteria
BXP64_RS01650	COG0012	GTP binding
BXP64_RS01750	COG1823	symporter activity
BXP64_RS01785	COG2233	PERMEase
BXP64_RS01825	COG3759	membrane
BXP64_RS01965	COG0523	cobalamin synthesis protein
BXP64_RS01980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXP64_RS01990	COG5609	conserved protein (DUF2294)
BXP64_RS02005	COG1647	Serine aminopeptidase, S33
BXP64_RS02010	COG0733	neurotransmitter:sodium symporter activity
BXP64_RS02015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BXP64_RS02020	COG0626	cystathionine gamma-synthase activity
BXP64_RS02030	COG2011	ABC-type metal ion transport system permease component
BXP64_RS02035	COG1464	Belongs to the NlpA lipoprotein family
BXP64_RS02070	COG0583	DNA-binding transcription factor activity
BXP64_RS02075	COG0069	glutamate synthase activity
BXP64_RS02075	COG0067	glutamate synthase
BXP64_RS02075	COG0070	glutamate synthase
BXP64_RS02080	COG0493	'glutamate synthase
BXP64_RS02095	COG1263	PTS System
BXP64_RS02095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BXP64_RS02100	COG0366	Alpha amylase catalytic
BXP64_RS02105	COG2188	Transcriptional regulator
BXP64_RS02125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BXP64_RS02160	COG1982	Orn Lys Arg decarboxylase major
BXP64_RS02170	COG3870	Protein conserved in bacteria
BXP64_RS02175	COG0470	DNA polymerase III
BXP64_RS02180	COG1774	PSP1 C-terminal conserved region
BXP64_RS02190	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BXP64_RS02200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BXP64_RS02210	COG0084	hydrolase, TatD family'
BXP64_RS02215	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BXP64_RS02225	COG4466	Protein conserved in bacteria
BXP64_RS02235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BXP64_RS02240	COG0251	oxidation-reduction process
BXP64_RS02285	COG2244	polysaccharide biosynthetic process
BXP64_RS02290	COG3956	TIGRFAM MazG family protein
BXP64_RS02295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BXP64_RS02305	COG1098	S1 RNA binding domain
BXP64_RS02320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BXP64_RS02345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BXP64_RS02440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXP64_RS02460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BXP64_RS02470	COG3880	PFAM UvrB UvrC protein
BXP64_RS02485	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BXP64_RS02490	COG4956	integral membrane protein (PIN domain superfamily)
BXP64_RS02515	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BXP64_RS02570	COG2813	Specifically methylates the guanine in position
BXP64_RS02610	COG1473	amidohydrolase
BXP64_RS02645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BXP64_RS02650	COG1428	Deoxynucleoside kinase
BXP64_RS02655	COG1428	Deoxynucleoside kinase
BXP64_RS02665	COG0561	phosphatase activity
BXP64_RS02710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BXP64_RS02825	COG0095	Lipoate-protein ligase
BXP64_RS02830	COG0083	homoserine kinase activity
BXP64_RS02850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXP64_RS02930	COG0667	Aldo Keto reductase
BXP64_RS02940	COG0655	NAD(P)H dehydrogenase (quinone) activity
BXP64_RS02950	COG1078	dGTPase activity
BXP64_RS02985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BXP64_RS02990	COG4139	cobalamin transport
BXP64_RS03085	COG0803	Belongs to the bacterial solute-binding protein 9 family
BXP64_RS03090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BXP64_RS03095	COG1121	(ABC) transporter
BXP64_RS03100	COG1321	iron dependent repressor
BXP64_RS03110	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BXP64_RS03120	COG1682	transport, permease protein
BXP64_RS03125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BXP64_RS03135	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BXP64_RS03140	COG1686	Belongs to the peptidase S11 family
BXP64_RS03145	COG1132	(ABC) transporter
BXP64_RS03150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BXP64_RS03160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BXP64_RS03165	COG1120	ATPase activity
BXP64_RS03170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXP64_RS03175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXP64_RS03180	COG2376	Dihydroxyacetone kinase
BXP64_RS03200	COG3949	Membrane
BXP64_RS03225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXP64_RS03240	COG1136	(ABC) transporter
BXP64_RS03245	COG0577	efflux transmembrane transporter activity
BXP64_RS03250	COG1392	Phosphate transport regulator
BXP64_RS03255	COG0306	phosphate transporter
BXP64_RS03260	COG1388	LysM domain
BXP64_RS03260	COG3942	CHAP domain
BXP64_RS03270	COG4977	sequence-specific DNA binding
BXP64_RS03270	COG1917	Cupin 2, conserved barrel domain protein
BXP64_RS03300	COG0583	DNA-binding transcription factor activity
BXP64_RS03315	COG2814	Major facilitator Superfamily
BXP64_RS03320	COG2839	Protein conserved in bacteria
BXP64_RS03335	COG2826	transposase and inactivated derivatives, IS30 family
BXP64_RS03360	COG1611	Belongs to the LOG family
BXP64_RS03380	COG4988	ABC transporter
BXP64_RS03385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BXP64_RS03395	COG0523	cobalamin synthesis protein
BXP64_RS03400	COG4989	oxidoreductase activity
BXP64_RS03410	COG0471	metal ion transport
BXP64_RS03415	COG0415	Belongs to the DNA photolyase family
BXP64_RS03445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BXP64_RS03450	COG1349	DNA-binding transcription factor activity
BXP64_RS03455	COG1105	Belongs to the carbohydrate kinase PfkB family
BXP64_RS03460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXP64_RS03460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXP64_RS03460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXP64_RS03465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BXP64_RS03470	COG1253	flavin adenine dinucleotide binding
BXP64_RS03475	COG0656	L-ascorbic acid biosynthetic process
BXP64_RS03480	COG0463	Glycosyl transferase, family 2
BXP64_RS03515	COG0720	synthase
BXP64_RS03525	COG0512	Glutamine amidotransferase of anthranilate synthase
BXP64_RS03525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BXP64_RS03530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXP64_RS03560	COG0488	(ABC) transporter
BXP64_RS03565	COG0514	ATP-dependent DNA helicase (RecQ)
BXP64_RS03570	COG0517	IMP dehydrogenase activity
BXP64_RS03570	COG1125	glycine betaine transport
BXP64_RS03575	COG1174	glycine betaine transport
BXP64_RS03610	COG3104	oligopeptide transport
BXP64_RS03640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXP64_RS03645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXP64_RS03655	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXP64_RS03660	COG4605	iron ion homeostasis
BXP64_RS03665	COG4604	ABC transporter, ATP-binding protein
BXP64_RS03670	COG4607	ABC-type enterochelin transport system periplasmic component
BXP64_RS03730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXP64_RS03735	COG1739	Uncharacterized protein family UPF0029
BXP64_RS03745	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BXP64_RS03750	COG1040	competence protein
BXP64_RS03780	COG1388	LysM domain
BXP64_RS03780	COG3942	CHAP domain
BXP64_RS03855	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BXP64_RS03875	COG0281	malic enzyme
BXP64_RS03930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BXP64_RS03935	COG1647	Serine aminopeptidase, S33
BXP64_RS03940	COG0557	exoribonuclease II activity
BXP64_RS04005	COG1278	Cold shock
BXP64_RS04045	COG0406	alpha-ribazole phosphatase activity
BXP64_RS04050	COG1279	arginine transmembrane transporter activity
BXP64_RS04075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXP64_RS04080	COG1393	Belongs to the ArsC family
BXP64_RS04095	COG3878	Protein conserved in bacteria
BXP64_RS04110	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BXP64_RS04125	COG2011	ABC-type metal ion transport system permease component
BXP64_RS04130	COG1464	Belongs to the NlpA lipoprotein family
BXP64_RS04150	COG0396	ATPase activity
BXP64_RS04155	COG0719	Fe-S assembly protein
BXP64_RS04165	COG0822	iron-sulfur transferase activity
BXP64_RS04185	COG1253	flavin adenine dinucleotide binding
BXP64_RS04195	COG1801	Protein of unknown function DUF72
BXP64_RS04200	COG0730	response to heat
BXP64_RS04215	COG4470	Protein conserved in bacteria
BXP64_RS04225	COG2445	Protein of unknown function DUF86
BXP64_RS04255	COG1696	Membrane protein involved in D-alanine export
BXP64_RS04265	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BXP64_RS04270	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BXP64_RS04275	COG4837	Protein of unknown function (DUF1462)
BXP64_RS04280	COG1252	NADH dehydrogenase
BXP64_RS04290	COG0316	Belongs to the HesB IscA family
BXP64_RS04300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXP64_RS04305	COG2056	Na+-H+ antiporter family
BXP64_RS04310	COG2050	protein possibly involved in aromatic compounds catabolism
BXP64_RS04365	COG1098	S1 RNA binding domain
BXP64_RS04370	COG1902	pentaerythritol trinitrate reductase activity
BXP64_RS04390	COG0584	glycerophosphoryl diester phosphodiesterase
BXP64_RS04410	COG0398	Pfam SNARE associated Golgi protein
BXP64_RS04455	COG0561	phosphatase activity
BXP64_RS04485	COG1881	PFAM PEBP family protein
BXP64_RS04515	COG0601	transmembrane transport
BXP64_RS04520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BXP64_RS04525	COG0444	Belongs to the ABC transporter superfamily
BXP64_RS04530	COG4608	Belongs to the ABC transporter superfamily
BXP64_RS04535	COG4166	transmembrane transport
BXP64_RS04540	COG0601	transmembrane transport
BXP64_RS04545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BXP64_RS04550	COG0444	Belongs to the ABC transporter superfamily
BXP64_RS04560	COG4166	transmembrane transport
BXP64_RS04585	COG1164	Oligoendopeptidase f
BXP64_RS04595	COG2346	COG2346, Truncated hemoglobins
BXP64_RS04610	COG2357	RelA SpoT domain protein
BXP64_RS04620	COG0564	pseudouridine synthase activity
BXP64_RS04625	COG2239	Acts as a magnesium transporter
BXP64_RS04630	COG0569	domain protein
BXP64_RS04630	COG0475	glutathione-regulated potassium exporter activity
BXP64_RS04640	COG0628	permease
BXP64_RS04645	COG1115	amino acid carrier protein
BXP64_RS04685	COG0861	Integral membrane protein TerC family
BXP64_RS04695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BXP64_RS04700	COG0737	Belongs to the 5'-nucleotidase family
BXP64_RS04715	COG4903	ComK protein
BXP64_RS04730	COG4873	Protein conserved in bacteria
BXP64_RS04780	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BXP64_RS04790	COG2314	TM2 domain
BXP64_RS04795	COG0456	acetyltransferase
BXP64_RS04800	COG1575	Belongs to the MenA family. Type 1 subfamily
BXP64_RS04810	COG1169	isochorismate synthase
BXP64_RS04850	COG0436	Aminotransferase
BXP64_RS04855	COG3594	Acyltransferase
BXP64_RS04885	COG1316	TRANSCRIPTIONal
BXP64_RS04935	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BXP64_RS04950	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BXP64_RS04995	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BXP64_RS05000	COG4172	Belongs to the ABC transporter superfamily
BXP64_RS05005	COG4721	ABC-type cobalt transport system, permease component
BXP64_RS05030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BXP64_RS05055	COG1271	oxidase subunit
BXP64_RS05060	COG1294	oxidase, subunit
BXP64_RS05065	COG0569	domain protein
BXP64_RS05135	COG1176	ABC-type spermidine putrescine transport system, permease component I
BXP64_RS05140	COG1177	transmembrane transport
BXP64_RS05145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BXP64_RS05170	COG0483	inositol monophosphate 1-phosphatase activity
BXP64_RS05180	COG1217	gtp-binding protein TYPA
BXP64_RS05190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BXP64_RS05200	COG0772	Belongs to the SEDS family
BXP64_RS05235	COG3679	Belongs to the UPF0342 family
BXP64_RS05240	COG0584	glycerophosphoryl diester phosphodiesterase
BXP64_RS05255	COG0742	ribosomal rna small subunit methyltransferase
BXP64_RS05315	COG4509	Sortase family
BXP64_RS05330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXP64_RS05365	COG1796	DNA polymerase
BXP64_RS05365	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BXP64_RS05390	COG2009	succinate dehydrogenase
BXP64_RS05395	COG1053	succinate dehydrogenase
BXP64_RS05400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BXP64_RS05520	COG1288	antiporter activity
BXP64_RS05555	COG1011	Hydrolase
BXP64_RS05580	COG4839	cell division protein FtsL
BXP64_RS05585	COG0768	penicillin binding
BXP64_RS05600	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BXP64_RS05605	COG0849	cell division
BXP64_RS05620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BXP64_RS05630	COG0762	integral membrane protein
BXP64_RS05635	COG2302	S4 RNA-binding domain
BXP64_RS05640	COG3599	regulation of cell shape
BXP64_RS05650	COG2514	catechol 2,3-dioxygenase activity
BXP64_RS05660	COG0564	pseudouridine synthase activity
BXP64_RS05670	COG2233	PERMEase
BXP64_RS05715	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BXP64_RS05730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BXP64_RS05735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BXP64_RS05745	COG2314	TM2 domain
BXP64_RS05760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BXP64_RS05760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXP64_RS05770	COG0631	protein serine/threonine phosphatase activity
BXP64_RS05785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BXP64_RS05800	COG1302	Protein conserved in bacteria
BXP64_RS05850	COG1196	nuclear chromosome segregation
BXP64_RS05855	COG0552	protein localization to endoplasmic reticulum
BXP64_RS05865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BXP64_RS05930	COG0758	DNA mediated transformation
BXP64_RS06030	COG0195	Participates in both transcription termination and antitermination
BXP64_RS06035	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BXP64_RS06060	COG0196	riboflavin kinase activity
BXP64_RS06090	COG2188	Transcriptional regulator
BXP64_RS06095	COG0612	Peptidase, M16
BXP64_RS06100	COG0612	Peptidase, M16
BXP64_RS06105	COG0300	oxidoreductase activity
BXP64_RS06125	COG1058	Belongs to the CinA family
BXP64_RS06125	COG1546	Belongs to the CinA family
BXP64_RS06145	COG1692	metallophosphoesterase
BXP64_RS06150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BXP64_RS06150	COG0674	pyruvate-flavodoxin oxidoreductase activity
BXP64_RS06155	COG1013	pyruvate-flavodoxin oxidoreductase activity
BXP64_RS06160	COG2826	transposase and inactivated derivatives, IS30 family
BXP64_RS06195	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BXP64_RS06200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BXP64_RS06225	COG1923	regulation of RNA biosynthetic process
BXP64_RS06235	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BXP64_RS06240	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BXP64_RS06245	COG0789	Transcriptional regulator
BXP64_RS06330	COG1525	nuclease
BXP64_RS06345	COG0527	aspartate kinase activity
BXP64_RS06350	COG0460	homoserine dehydrogenase
BXP64_RS06355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BXP64_RS06380	COG0833	amino acid
BXP64_RS06410	COG2340	Cysteine-rich secretory protein family
BXP64_RS06445	COG4846	Membrane protein involved in cytochrome C biogenesis
BXP64_RS06465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BXP64_RS06485	COG0824	Thioesterase
BXP64_RS06510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BXP64_RS06520	COG1115	amino acid carrier protein
BXP64_RS06535	COG0628	permease
BXP64_RS06560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BXP64_RS06570	COG1363	Peptidase, m42
BXP64_RS06575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXP64_RS06580	COG0512	Glutamine amidotransferase of anthranilate synthase
BXP64_RS06620	COG0561	phosphatase activity
BXP64_RS06670	COG0704	Plays a role in the regulation of phosphate uptake
BXP64_RS06680	COG0581	inorganic phosphate transmembrane transporter activity
BXP64_RS06685	COG0573	inorganic phosphate transmembrane transporter activity
BXP64_RS06705	COG0488	(ABC) transporter
BXP64_RS06710	COG0527	aspartate kinase activity
BXP64_RS06715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BXP64_RS06750	COG2808	Putative FMN-binding domain
BXP64_RS06795	COG4548	von Willebrand factor, type A
BXP64_RS06800	COG0714	Associated with various cellular activities
BXP64_RS06845	COG0671	phosphoesterase, PA-phosphatase related
BXP64_RS06920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BXP64_RS06940	COG0531	amino acid
BXP64_RS06955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXP64_RS06960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BXP64_RS06975	COG0116	Belongs to the methyltransferase superfamily
BXP64_RS07005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXP64_RS07005	COG4499	WXG100 protein secretion system (Wss), protein YukC
BXP64_RS07015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BXP64_RS07020	COG3935	DnaD domain protein
BXP64_RS07045	COG0438	transferase activity, transferring glycosyl groups
BXP64_RS07050	COG1694	Mazg nucleotide pyrophosphohydrolase
BXP64_RS07055	COG2738	Putative neutral zinc metallopeptidase
BXP64_RS07060	COG4347	Protein of unknown function (DUF1405)
BXP64_RS07100	COG0142	geranyltranstransferase activity
BXP64_RS07165	COG0492	ferredoxin-NADP+ reductase activity
BXP64_RS07180	COG0514	ATP-dependent DNA helicase (RecQ)
BXP64_RS07190	COG1141	Ferredoxin
BXP64_RS07235	COG5002	protein histidine kinase activity
BXP64_RS07240	COG0745	RESPONSE REGULATOR receiver
BXP64_RS07245	COG1187	pseudouridine synthase activity
BXP64_RS07270	COG0735	belongs to the Fur family
BXP64_RS07275	COG0494	nUDIX hydrolase
BXP64_RS07280	COG0667	Aldo Keto reductase
BXP64_RS07305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BXP64_RS07315	COG0366	Alpha amylase catalytic
BXP64_RS07320	COG1609	Transcriptional regulator
BXP64_RS07340	COG2195	Cleaves the N-terminal amino acid of tripeptides
BXP64_RS07350	COG4129	membrane
BXP64_RS07360	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXP64_RS07365	COG0022	dehydrogenase e1 component
BXP64_RS07370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BXP64_RS07375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXP64_RS07380	COG0497	DNA recombination
BXP64_RS07410	COG1302	Protein conserved in bacteria
BXP64_RS07415	COG0439	Biotin carboxylase
BXP64_RS07420	COG0511	ligase activity, forming carbon-carbon bonds
BXP64_RS07430	COG0006	proline dipeptidase activity
BXP64_RS07445	COG0095	Lipoate-protein ligase
BXP64_RS07450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BXP64_RS07495	COG4537	Required for transformation and DNA binding
BXP64_RS07500	COG1459	type II secretion system
BXP64_RS07505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BXP64_RS07510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXP64_RS07515	COG0011	TIGRFAM Protein of
BXP64_RS07520	COG1940	carbohydrate kinase activity
BXP64_RS07525	COG4483	Protein conserved in bacteria
BXP64_RS07535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BXP64_RS07545	COG0768	penicillin binding
BXP64_RS07560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BXP64_RS07565	COG1121	(ABC) transporter
BXP64_RS07575	COG0513	Belongs to the DEAD box helicase family
BXP64_RS07585	COG2384	SAM-dependent methyltransferase
BXP64_RS07605	COG0517	IMP dehydrogenase activity
BXP64_RS07625	COG0295	cytidine deaminase activity
BXP64_RS07640	COG1702	phosphate starvation-inducible protein PhoH
BXP64_RS07655	COG1030	water channel activity
BXP64_RS07665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BXP64_RS07670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BXP64_RS07700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BXP64_RS07720	COG1466	dna polymerase III delta subunit
BXP64_RS07730	COG2131	deaminase
BXP64_RS07740	COG2226	methyltransferase
BXP64_RS07745	COG0799	negative regulation of ribosome biogenesis
BXP64_RS07750	COG1713	HD superfamily hydrolase involved in NAD metabolism
BXP64_RS07760	COG1534	Rna-binding protein
BXP64_RS07770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BXP64_RS07775	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BXP64_RS07795	COG3177	Filamentation induced by cAMP protein fic
BXP64_RS07800	COG1914	H( )-stimulated, divalent metal cation uptake system
BXP64_RS07810	COG0439	Biotin carboxylase
BXP64_RS07815	COG0511	ligase activity, forming carbon-carbon bonds
BXP64_RS07820	COG1984	allophanate hydrolase subunit 2
BXP64_RS07825	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BXP64_RS07840	COG0826	peptidase U32
BXP64_RS07845	COG0826	peptidase U32
BXP64_RS07875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BXP64_RS07900	COG1104	cysteine desulfurase activity
BXP64_RS07905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXP64_RS07915	COG3237	CsbD-like
BXP64_RS07920	COG1959	2 iron, 2 sulfur cluster binding
BXP64_RS07925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BXP64_RS07930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BXP64_RS07975	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BXP64_RS07975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BXP64_RS07980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXP64_RS07980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXP64_RS07985	COG1862	Preprotein translocase
BXP64_RS08025	COG2868	ribosomal protein
BXP64_RS08070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BXP64_RS08080	COG0285	dihydrofolate synthase activity
BXP64_RS08090	COG2818	Glycosylase
BXP64_RS08125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXP64_RS08160	COG4112	unkown
BXP64_RS08185	COG0833	amino acid
BXP64_RS08200	COG1484	DNA-dependent DNA replication
BXP64_RS08230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXP64_RS08230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXP64_RS08240	COG5002	protein histidine kinase activity
BXP64_RS08245	COG0745	RESPONSE REGULATOR receiver
BXP64_RS08260	COG0372	Belongs to the citrate synthase family
BXP64_RS08265	COG1113	amino acid transport
BXP64_RS08290	COG0281	malic enzyme
BXP64_RS08300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BXP64_RS08315	COG4109	DRTGG domain
BXP64_RS08360	COG0827	DNA restriction-modification system
BXP64_RS08370	COG0730	response to heat
BXP64_RS08380	COG1104	cysteine desulfurase activity
BXP64_RS08390	COG1956	GAF domain-containing protein
BXP64_RS08405	COG0584	glycerophosphoryl diester phosphodiesterase
BXP64_RS08410	COG1764	response to oxidative stress
BXP64_RS08415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BXP64_RS08420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXP64_RS08435	COG1263	PTS System
BXP64_RS08435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BXP64_RS08440	COG0204	Acyl-transferase
BXP64_RS08445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXP64_RS08465	COG5386	Cell surface protein
BXP64_RS08480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXP64_RS08485	COG0454	-acetyltransferase
BXP64_RS08505	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BXP64_RS08505	COG1605	Chorismate mutase
BXP64_RS08530	COG1674	ftsk spoiiie
BXP64_RS08535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXP64_RS08545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXP64_RS08550	COG1363	Peptidase, m42
BXP64_RS08560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXP64_RS08570	COG0510	thiamine kinase activity
BXP64_RS08590	COG1187	pseudouridine synthase activity
BXP64_RS08595	COG2244	polysaccharide biosynthetic process
BXP64_RS08600	COG2081	HI0933 family
BXP64_RS08620	COG2814	Major facilitator Superfamily
BXP64_RS08625	COG1242	4 iron, 4 sulfur cluster binding
BXP64_RS08630	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BXP64_RS08640	COG2267	carboxylic ester hydrolase activity
BXP64_RS08675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXP64_RS08675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXP64_RS08695	COG4193	domain, Protein
BXP64_RS08695	COG5632	N-Acetylmuramoyl-L-alanine amidase
BXP64_RS08695	COG3266	domain, Protein
BXP64_RS08730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BXP64_RS08750	COG0656	L-ascorbic acid biosynthetic process
BXP64_RS08770	COG1506	peptidase
BXP64_RS08775	COG2816	NAD+ diphosphatase activity
BXP64_RS08865	COG5492	domain, Protein
BXP64_RS08905	COG2826	transposase and inactivated derivatives, IS30 family
BXP64_RS09015	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BXP64_RS09045	COG1131	(ABC) transporter
BXP64_RS09050	COG0537	adenosine 5'-monophosphoramidase activity
BXP64_RS09080	COG0420	3'-5' exonuclease activity
BXP64_RS09110	COG2197	response regulator
BXP64_RS09115	COG2203	Gaf domain
BXP64_RS09115	COG4585	Histidine kinase
BXP64_RS09120	COG0564	pseudouridine synthase activity
BXP64_RS09155	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BXP64_RS09160	COG1126	abc transporter atp-binding protein
BXP64_RS09165	COG0765	amino acid transport
BXP64_RS09330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXP64_RS09335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BXP64_RS09345	COG4129	membrane
BXP64_RS09365	COG1194	a g-specific adenine glycosylase
BXP64_RS09370	COG1988	membrane-bound metal-dependent
BXP64_RS09385	COG1388	LysM domain
BXP64_RS09385	COG1134	teichoic acid transport
BXP64_RS09415	COG0535	radical SAM domain protein
BXP64_RS09420	COG1607	acyl-coa hydrolase
BXP64_RS09425	COG2309	aminopeptidase activity
BXP64_RS09445	COG1295	ribonuclease BN
BXP64_RS09570	COG4851	CamS sex pheromone cAM373 precursor
BXP64_RS09590	COG4496	protein, YerC YecD
BXP64_RS09625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BXP64_RS09635	COG0077	Prephenate dehydratase
BXP64_RS09655	COG1335	isochorismatase
BXP64_RS09670	COG1012	belongs to the aldehyde dehydrogenase family
BXP64_RS09680	COG3682	Transcriptional regulator
BXP64_RS09725	COG4974	Belongs to the 'phage' integrase family
BXP64_RS09775	COG1131	(ABC) transporter
BXP64_RS09790	COG1725	Transcriptional regulator
BXP64_RS09845	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXP64_RS09845	COG1388	LysM domain
BXP64_RS09890	COG0739	heme binding
BXP64_RS09940	COG0740	serine-type endopeptidase activity
BXP64_RS10115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BXP64_RS10170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BXP64_RS10250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXP64_RS10255	COG1621	beta-fructofuranosidase activity
BXP64_RS10260	COG1609	Transcriptional regulator
BXP64_RS10265	COG0004	ammonium transporteR
BXP64_RS10270	COG0425	Belongs to the sulfur carrier protein TusA family
BXP64_RS10275	COG2391	methyltransferase activity
BXP64_RS10285	COG0488	(ABC) transporter
BXP64_RS10295	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BXP64_RS10305	COG0456	acetyltransferase
BXP64_RS10310	COG1214	PFAM Peptidase M22, glycoprotease
BXP64_RS10315	COG0802	atpase or kinase
BXP64_RS10330	COG0028	Belongs to the TPP enzyme family
BXP64_RS10405	COG2183	response to ionizing radiation
BXP64_RS10410	COG1191	sigma factor activity
BXP64_RS10420	COG1366	Belongs to the anti-sigma-factor antagonist family
BXP64_RS10425	COG2208	phosphoserine phosphatase activity
BXP64_RS10460	COG3428	Bacterial PH domain
BXP64_RS10490	COG2205	protein histidine kinase activity
BXP64_RS10495	COG0745	RESPONSE REGULATOR receiver
BXP64_RS10505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BXP64_RS10515	COG0772	Belongs to the SEDS family
BXP64_RS10530	COG1937	Protein conserved in bacteria
BXP64_RS10540	COG1418	mRNA catabolic process
BXP64_RS10590	COG0629	single-stranded DNA binding
BXP64_RS10670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BXP64_RS10695	COG0009	L-threonylcarbamoyladenylate synthase
BXP64_RS10700	COG2890	protein-(glutamine-N5) methyltransferase activity
BXP64_RS10725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BXP64_RS10765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXP64_RS10815	COG0813	purine-nucleoside phosphorylase activity
BXP64_RS10820	COG0783	Belongs to the Dps family
BXP64_RS10840	COG1482	cell wall glycoprotein biosynthetic process
BXP64_RS10845	COG0702	epimerase
BXP64_RS10850	COG0640	Transcriptional regulator
BXP64_RS10885	COG0561	phosphatase activity
BXP64_RS10890	COG1119	ATPase activity
BXP64_RS10915	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BXP64_RS10980	COG3711	transcriptional antiterminator
BXP64_RS11010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BXP64_RS11070	COG0489	protein tyrosine kinase activity
BXP64_RS11075	COG2814	Major facilitator Superfamily
BXP64_RS11090	COG1272	protein, Hemolysin III
BXP64_RS11100	COG1988	membrane-bound metal-dependent
BXP64_RS11110	COG3314	Sporulation integral membrane protein YlbJ
BXP64_RS11115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXP64_RS11120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXP64_RS11125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BXP64_RS11135	COG3457	Alanine racemase
BXP64_RS11140	COG4264	IucA IucC family
BXP64_RS11145	COG2814	Major facilitator Superfamily
BXP64_RS11170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BXP64_RS11180	COG2130	NADP-dependent
BXP64_RS11245	COG0656	L-ascorbic acid biosynthetic process
BXP64_RS11250	COG0789	Transcriptional regulator
BXP64_RS11260	COG5492	domain, Protein
BXP64_RS11275	COG0438	transferase activity, transferring glycosyl groups
BXP64_RS11290	COG3527	Alpha-acetolactate decarboxylase
BXP64_RS11295	COG0028	Belongs to the TPP enzyme family
BXP64_RS11305	COG2826	transposase and inactivated derivatives, IS30 family
BXP64_RS11380	COG0201	protein transport
BXP64_RS11495	COG2252	PERMEase
BXP64_RS11540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXP64_RS11615	COG1763	Mo-molybdopterin cofactor biosynthetic process
BXP64_RS11635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BXP64_RS11640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BXP64_RS11645	COG4149	molybdate abc transporter
BXP64_RS11650	COG0725	ABC transporter, periplasmic molybdate-binding protein
BXP64_RS11665	COG1268	BioY protein
BXP64_RS11680	COG1960	acyl-CoA dehydrogenase activity
BXP64_RS11685	COG4413	Urea transporter
BXP64_RS11760	COG1757	Na H antiporter
BXP64_RS11775	COG3942	CHAP domain
BXP64_RS11840	COG1266	CAAX protease self-immunity
BXP64_RS11855	COG1113	amino acid transport
BXP64_RS11875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BXP64_RS11880	COG0385	Bile acid
BXP64_RS11890	COG1263	PTS System
BXP64_RS11890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BXP64_RS11895	COG1737	Transcriptional regulator
BXP64_RS11915	COG1028	Short-chain dehydrogenase reductase Sdr
BXP64_RS11920	COG1473	amidohydrolase
BXP64_RS11935	COG0583	DNA-binding transcription factor activity
BXP64_RS11955	COG2258	MOSC domain
BXP64_RS11975	COG1668	transmembrane transport
BXP64_RS11980	COG4152	abc transporter atp-binding protein
BXP64_RS11985	COG3152	Membrane
BXP64_RS12000	COG0786	glutamate:sodium symporter activity
BXP64_RS12010	COG0598	Magnesium transport protein CorA
BXP64_RS12025	COG0657	acetylesterase activity
BXP64_RS12035	COG2814	Major facilitator Superfamily
BXP64_RS12040	COG1566	PFAM secretion protein HlyD family protein
BXP64_RS12055	COG2814	Major facilitator Superfamily
BXP64_RS12120	COG1620	l-lactate permease
BXP64_RS12130	COG2826	transposase and inactivated derivatives, IS30 family
BXP64_RS12145	COG0604	alcohol dehydrogenase
BXP64_RS12175	COG1511	domain protein
BXP64_RS12190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BXP64_RS12190	COG1263	PTS System
BXP64_RS12205	COG3871	stress protein (general stress protein 26)
BXP64_RS12255	COG0789	Transcriptional regulator
BXP64_RS12275	COG2181	nitrate reductase activity
BXP64_RS12285	COG1140	nitrate reductase beta subunit
BXP64_RS12290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BXP64_RS12300	COG2146	nitrite reductase [NAD(P)H] activity
BXP64_RS12305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXP64_RS12315	COG0454	-acetyltransferase
BXP64_RS12325	COG2116	formate transmembrane transporter activity
BXP64_RS12340	COG3443	Belongs to the bacterial solute-binding protein 9 family
BXP64_RS12340	COG0803	Belongs to the bacterial solute-binding protein 9 family
BXP64_RS12365	COG1126	abc transporter atp-binding protein
BXP64_RS12370	COG0765	amino acid transport
BXP64_RS12375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXP64_RS12380	COG2814	Major facilitator Superfamily
BXP64_RS12400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BXP64_RS12450	COG0156	8-amino-7-oxononanoate synthase activity
BXP64_RS12460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BXP64_RS12465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BXP64_RS12480	COG1132	(ABC) transporter
BXP64_RS12485	COG1132	(ABC) transporter
BXP64_RS12485	COG2375	cellular response to nickel ion
BXP64_RS12505	COG1929	Belongs to the glycerate kinase type-1 family
BXP64_RS12515	COG2814	Major facilitator Superfamily
BXP64_RS12535	COG1113	amino acid transport
BXP64_RS12545	COG0531	amino acid
BXP64_RS12565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BXP64_RS12575	COG1174	glycine betaine transport
BXP64_RS12585	COG1174	glycine betaine transport
BXP64_RS12600	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BXP64_RS12605	COG0531	amino acid
BXP64_RS12610	COG2272	Belongs to the type-B carboxylesterase lipase family
BXP64_RS12615	COG2814	Major facilitator Superfamily
BXP64_RS12620	COG0390	transport system, permease component
BXP64_RS12625	COG4619	ABC transporter
BXP64_RS12630	COG1363	Peptidase, m42
BXP64_RS12635	COG4808	Protein conserved in bacteria
BXP64_RS12640	COG0069	glutamate synthase activity
BXP64_RS12655	COG1124	(ABC) transporter
BXP64_RS12665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BXP64_RS12670	COG0601	transmembrane transport
BXP64_RS12675	COG0747	negative chemotaxis
BXP64_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
BXP64_RS12710	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BXP64_RS12715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXP64_RS12865	COG1070	Carbohydrate kinase
BXP64_RS12870	COG1802	Transcriptional regulator
BXP64_RS12875	COG0789	Transcriptional regulator
BXP64_RS12880	COG2357	RelA SpoT domain protein
BXP64_RS12885	COG4876	unkown
BXP64_RS12900	COG2271	Major facilitator Superfamily
BXP64_RS12905	COG0586	Pfam SNARE associated Golgi protein
BXP64_RS12915	COG2814	Major facilitator Superfamily
BXP64_RS12920	COG1846	Transcriptional regulator
BXP64_RS12930	COG1131	(ABC) transporter
BXP64_RS12950	COG0400	carboxylic ester hydrolase activity
BXP64_RS12955	COG0346	lactoylglutathione lyase activity
BXP64_RS12960	COG1846	Transcriptional regulator
BXP64_RS12970	COG2514	catechol 2,3-dioxygenase activity
BXP64_RS12985	COG0561	phosphatase activity
BXP64_RS12990	COG3764	Sortase (surface protein transpeptidase)
BXP64_RS13010	COG1760	l-serine dehydratase
BXP64_RS13015	COG1760	l-serine dehydratase
BXP64_RS13030	COG0697	spore germination
BXP64_RS13035	COG0657	acetylesterase activity
BXP64_RS13055	COG0028	Belongs to the TPP enzyme family
BXP64_RS13070	COG0583	DNA-binding transcription factor activity
BXP64_RS13080	COG3942	CHAP domain
BXP64_RS13090	COG3425	synthase
BXP64_RS13095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BXP64_RS13120	COG2409	Drug exporters of the RND superfamily
BXP64_RS13165	COG0436	Aminotransferase
BXP64_RS13270	COG0596	Alpha beta hydrolase
BXP64_RS13310	COG3001	Fructosamine kinase
BXP64_RS13315	COG0167	dihydroorotate dehydrogenase activity
BXP64_RS13420	COG0596	Alpha beta hydrolase
BXP64_RS13460	COG3001	Fructosamine kinase
BXP64_RS13465	COG0167	dihydroorotate dehydrogenase activity
BXP64_RS13515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BXP64_RS13520	COG3527	Alpha-acetolactate decarboxylase
BXP64_RS13535	COG0531	amino acid
BXP64_RS13565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXP64_RS13585	COG1012	belongs to the aldehyde dehydrogenase family
BXP64_RS13595	COG1510	regulation of RNA biosynthetic process
BXP64_RS13600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BXP64_RS13625	COG2851	Citrate transporter
BXP64_RS13640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BXP64_RS13650	COG0386	Belongs to the glutathione peroxidase family
BXP64_RS13675	COG1136	(ABC) transporter
BXP64_RS13680	COG2205	protein histidine kinase activity
BXP64_RS13685	COG0745	RESPONSE REGULATOR receiver
BXP64_RS13695	COG1785	Belongs to the alkaline phosphatase family
BXP64_RS13705	COG1846	Transcriptional regulator
BXP64_RS13750	COG1438	arginine binding
BXP64_RS13770	COG3711	transcriptional antiterminator
BXP64_RS13770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXP64_RS13775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXP64_RS13775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXP64_RS13775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXP64_RS13780	COG1482	cell wall glycoprotein biosynthetic process
BXP64_RS13790	COG3942	CHAP domain
BXP64_RS13790	COG1705	Flagellar rod assembly protein muramidase FlgJ
BXP64_RS13795	COG1535	isochorismatase
BXP64_RS13795	COG3433	isochorismatase activity
BXP64_RS13810	COG0438	transferase activity, transferring glycosyl groups
BXP64_RS13825	COG1073	alpha beta
BXP64_RS13845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXP64_RS13875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXP64_RS13970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXP64_RS14040	COG0471	metal ion transport
BXP64_RS14050	COG2962	Rard protein
BXP64_RS14060	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BXP64_RS14075	COG1136	(ABC) transporter
BXP64_RS14080	COG0577	efflux transmembrane transporter activity
BXP64_RS14090	COG1278	Cold shock
BXP64_RS14110	COG1475	DNA binding