locus-tag	class	description
CU118_RS00020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU118_RS00035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU118_RS00045	COG3880	PFAM UvrB UvrC protein
CU118_RS00060	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CU118_RS00065	COG4956	integral membrane protein (PIN domain superfamily)
CU118_RS00090	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CU118_RS00150	COG2813	Specifically methylates the guanine in position
CU118_RS00195	COG1473	amidohydrolase
CU118_RS00230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CU118_RS00235	COG1428	Deoxynucleoside kinase
CU118_RS00240	COG1428	Deoxynucleoside kinase
CU118_RS00250	COG0561	phosphatase activity
CU118_RS00285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CU118_RS00400	COG0095	Lipoate-protein ligase
CU118_RS00405	COG0083	homoserine kinase activity
CU118_RS00425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CU118_RS00465	COG0667	Aldo Keto reductase
CU118_RS00470	COG0655	NAD(P)H dehydrogenase (quinone) activity
CU118_RS00480	COG1078	dGTPase activity
CU118_RS00520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CU118_RS00525	COG4139	cobalamin transport
CU118_RS00575	COG4974	Belongs to the 'phage' integrase family
CU118_RS00620	COG0803	Belongs to the bacterial solute-binding protein 9 family
CU118_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU118_RS00630	COG1121	(ABC) transporter
CU118_RS00635	COG1321	iron dependent repressor
CU118_RS00645	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CU118_RS00655	COG1682	transport, permease protein
CU118_RS00660	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CU118_RS00670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CU118_RS00675	COG1686	Belongs to the peptidase S11 family
CU118_RS00680	COG1132	(ABC) transporter
CU118_RS00685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU118_RS00695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CU118_RS00700	COG1120	ATPase activity
CU118_RS00705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU118_RS00710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU118_RS00715	COG2376	Dihydroxyacetone kinase
CU118_RS00735	COG3949	Membrane
CU118_RS00760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CU118_RS00775	COG1136	(ABC) transporter
CU118_RS00780	COG0577	efflux transmembrane transporter activity
CU118_RS00785	COG1392	Phosphate transport regulator
CU118_RS00790	COG0306	phosphate transporter
CU118_RS00795	COG3942	CHAP domain
CU118_RS00795	COG1388	LysM domain
CU118_RS00805	COG4977	sequence-specific DNA binding
CU118_RS00805	COG1917	Cupin 2, conserved barrel domain protein
CU118_RS00835	COG0583	DNA-binding transcription factor activity
CU118_RS00850	COG2814	Major facilitator Superfamily
CU118_RS00855	COG2839	Protein conserved in bacteria
CU118_RS00885	COG1611	Belongs to the LOG family
CU118_RS00905	COG4988	ABC transporter
CU118_RS00910	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CU118_RS00920	COG0523	cobalamin synthesis protein
CU118_RS00925	COG4989	oxidoreductase activity
CU118_RS00935	COG0471	metal ion transport
CU118_RS00940	COG0415	Belongs to the DNA photolyase family
CU118_RS00970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CU118_RS00975	COG1349	DNA-binding transcription factor activity
CU118_RS00980	COG1105	Belongs to the carbohydrate kinase PfkB family
CU118_RS00985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU118_RS00985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU118_RS00985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU118_RS00990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CU118_RS00995	COG1253	flavin adenine dinucleotide binding
CU118_RS01000	COG0656	L-ascorbic acid biosynthetic process
CU118_RS01005	COG0463	Glycosyl transferase, family 2
CU118_RS01040	COG0720	synthase
CU118_RS01050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CU118_RS01050	COG0512	Glutamine amidotransferase of anthranilate synthase
CU118_RS01055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CU118_RS01085	COG0488	(ABC) transporter
CU118_RS01090	COG0514	ATP-dependent DNA helicase (RecQ)
CU118_RS01095	COG0517	IMP dehydrogenase activity
CU118_RS01095	COG1125	glycine betaine transport
CU118_RS01100	COG1174	glycine betaine transport
CU118_RS01125	COG3104	oligopeptide transport
CU118_RS01155	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU118_RS01160	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU118_RS01175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU118_RS01180	COG4605	iron ion homeostasis
CU118_RS01185	COG4604	ABC transporter, ATP-binding protein
CU118_RS01190	COG4607	ABC-type enterochelin transport system periplasmic component
CU118_RS01245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CU118_RS01250	COG1739	Uncharacterized protein family UPF0029
CU118_RS01260	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CU118_RS01265	COG1040	competence protein
CU118_RS01295	COG1388	LysM domain
CU118_RS01295	COG3942	CHAP domain
CU118_RS01355	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CU118_RS01375	COG0281	malic enzyme
CU118_RS01425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CU118_RS01430	COG1647	Serine aminopeptidase, S33
CU118_RS01435	COG0557	exoribonuclease II activity
CU118_RS01505	COG1278	Cold shock
CU118_RS01545	COG0406	alpha-ribazole phosphatase activity
CU118_RS01550	COG1279	arginine transmembrane transporter activity
CU118_RS01575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CU118_RS01580	COG1393	Belongs to the ArsC family
CU118_RS01595	COG3878	Protein conserved in bacteria
CU118_RS01600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CU118_RS01615	COG2011	ABC-type metal ion transport system permease component
CU118_RS01620	COG1464	Belongs to the NlpA lipoprotein family
CU118_RS01640	COG0396	ATPase activity
CU118_RS01645	COG0719	Fe-S assembly protein
CU118_RS01655	COG0822	iron-sulfur transferase activity
CU118_RS01670	COG1253	flavin adenine dinucleotide binding
CU118_RS01680	COG1801	Protein of unknown function DUF72
CU118_RS01685	COG0730	response to heat
CU118_RS01700	COG4470	Protein conserved in bacteria
CU118_RS01710	COG2445	Protein of unknown function DUF86
CU118_RS01740	COG1696	Membrane protein involved in D-alanine export
CU118_RS01750	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CU118_RS01755	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CU118_RS01760	COG4837	Protein of unknown function (DUF1462)
CU118_RS01765	COG1252	NADH dehydrogenase
CU118_RS01775	COG0316	Belongs to the HesB IscA family
CU118_RS01785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CU118_RS01790	COG2056	Na+-H+ antiporter family
CU118_RS01800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CU118_RS01850	COG1098	S1 RNA binding domain
CU118_RS01855	COG1902	pentaerythritol trinitrate reductase activity
CU118_RS01875	COG0584	glycerophosphoryl diester phosphodiesterase
CU118_RS01900	COG0398	Pfam SNARE associated Golgi protein
CU118_RS01950	COG0561	phosphatase activity
CU118_RS01975	COG1881	PFAM PEBP family protein
CU118_RS02010	COG0601	transmembrane transport
CU118_RS02015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU118_RS02020	COG0444	Belongs to the ABC transporter superfamily
CU118_RS02025	COG4608	Belongs to the ABC transporter superfamily
CU118_RS02030	COG4166	transmembrane transport
CU118_RS02035	COG0747	negative chemotaxis
CU118_RS02040	COG0444	Belongs to the ABC transporter superfamily
CU118_RS02045	COG4608	Belongs to the ABC transporter superfamily
CU118_RS02050	COG0601	transmembrane transport
CU118_RS02055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU118_RS02080	COG1164	Oligoendopeptidase f
CU118_RS02090	COG2346	COG2346, Truncated hemoglobins
CU118_RS02105	COG2357	RelA SpoT domain protein
CU118_RS02115	COG0564	pseudouridine synthase activity
CU118_RS02120	COG2239	Acts as a magnesium transporter
CU118_RS02125	COG0475	glutathione-regulated potassium exporter activity
CU118_RS02125	COG0569	domain protein
CU118_RS02135	COG0628	permease
CU118_RS02140	COG1115	amino acid carrier protein
CU118_RS02180	COG0861	Integral membrane protein TerC family
CU118_RS02190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CU118_RS02195	COG0737	Belongs to the 5'-nucleotidase family
CU118_RS02210	COG4903	ComK protein
CU118_RS02225	COG4873	Protein conserved in bacteria
CU118_RS02275	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CU118_RS02285	COG2314	TM2 domain
CU118_RS02290	COG0456	acetyltransferase
CU118_RS02295	COG1575	Belongs to the MenA family. Type 1 subfamily
CU118_RS02305	COG1169	isochorismate synthase
CU118_RS02315	COG2267	carboxylic ester hydrolase activity
CU118_RS02340	COG0436	Aminotransferase
CU118_RS02345	COG3594	Acyltransferase
CU118_RS02375	COG1316	TRANSCRIPTIONal
CU118_RS02420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CU118_RS02435	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CU118_RS02475	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CU118_RS02480	COG4172	Belongs to the ABC transporter superfamily
CU118_RS02485	COG4721	ABC-type cobalt transport system, permease component
CU118_RS02510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CU118_RS02530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CU118_RS02535	COG1271	oxidase subunit
CU118_RS02540	COG1294	oxidase, subunit
CU118_RS02545	COG0569	domain protein
CU118_RS02610	COG1176	ABC-type spermidine putrescine transport system, permease component I
CU118_RS02615	COG1177	transmembrane transport
CU118_RS02620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CU118_RS02645	COG0483	inositol monophosphate 1-phosphatase activity
CU118_RS02655	COG1217	gtp-binding protein TYPA
CU118_RS02665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CU118_RS02675	COG0772	Belongs to the SEDS family
CU118_RS02710	COG3679	Belongs to the UPF0342 family
CU118_RS02730	COG0742	ribosomal rna small subunit methyltransferase
CU118_RS02795	COG4509	Sortase family
CU118_RS02810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CU118_RS02850	COG1796	DNA polymerase
CU118_RS02850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CU118_RS02875	COG2009	succinate dehydrogenase
CU118_RS02880	COG1053	succinate dehydrogenase
CU118_RS02885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CU118_RS02985	COG1288	antiporter activity
CU118_RS03020	COG1011	Hydrolase
CU118_RS03045	COG4839	cell division protein FtsL
CU118_RS03050	COG0768	penicillin binding
CU118_RS03065	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CU118_RS03070	COG0849	cell division
CU118_RS03085	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CU118_RS03095	COG0762	integral membrane protein
CU118_RS03100	COG2302	S4 RNA-binding domain
CU118_RS03105	COG3599	regulation of cell shape
CU118_RS03115	COG2514	catechol 2,3-dioxygenase activity
CU118_RS03125	COG0564	pseudouridine synthase activity
CU118_RS03135	COG2233	PERMEase
CU118_RS03180	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CU118_RS03195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CU118_RS03200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CU118_RS03225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CU118_RS03225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CU118_RS03235	COG0631	protein serine/threonine phosphatase activity
CU118_RS03250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CU118_RS03265	COG1302	Protein conserved in bacteria
CU118_RS03325	COG1196	nuclear chromosome segregation
CU118_RS03330	COG0552	protein localization to endoplasmic reticulum
CU118_RS03340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CU118_RS03390	COG0758	DNA mediated transformation
CU118_RS03490	COG0195	Participates in both transcription termination and antitermination
CU118_RS03495	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CU118_RS03520	COG0196	riboflavin kinase activity
CU118_RS03550	COG2188	Transcriptional regulator
CU118_RS03555	COG0612	Peptidase, M16
CU118_RS03560	COG0612	Peptidase, M16
CU118_RS03565	COG0300	oxidoreductase activity
CU118_RS03585	COG1546	Belongs to the CinA family
CU118_RS03585	COG1058	Belongs to the CinA family
CU118_RS03605	COG1692	metallophosphoesterase
CU118_RS03610	COG0674	pyruvate-flavodoxin oxidoreductase activity
CU118_RS03610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CU118_RS03615	COG1013	pyruvate-flavodoxin oxidoreductase activity
CU118_RS03650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CU118_RS03655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CU118_RS03680	COG1923	regulation of RNA biosynthetic process
CU118_RS03690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CU118_RS03695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CU118_RS03700	COG0789	Transcriptional regulator
CU118_RS03790	COG1131	(ABC) transporter
CU118_RS03805	COG2197	response regulator
CU118_RS03815	COG1525	nuclease
CU118_RS03830	COG0527	aspartate kinase activity
CU118_RS03835	COG0460	homoserine dehydrogenase
CU118_RS03840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CU118_RS03865	COG0833	amino acid
CU118_RS03935	COG4846	Membrane protein involved in cytochrome C biogenesis
CU118_RS03955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU118_RS03965	COG0824	Thioesterase
CU118_RS03985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CU118_RS03995	COG1115	amino acid carrier protein
CU118_RS04005	COG0628	permease
CU118_RS04030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CU118_RS04040	COG1363	Peptidase, m42
CU118_RS04045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CU118_RS04050	COG0512	Glutamine amidotransferase of anthranilate synthase
CU118_RS04095	COG0561	phosphatase activity
CU118_RS04140	COG0704	Plays a role in the regulation of phosphate uptake
CU118_RS04150	COG0581	inorganic phosphate transmembrane transporter activity
CU118_RS04155	COG0573	inorganic phosphate transmembrane transporter activity
CU118_RS04170	COG0488	(ABC) transporter
CU118_RS04175	COG0527	aspartate kinase activity
CU118_RS04180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CU118_RS04260	COG4548	von Willebrand factor, type A
CU118_RS04265	COG0714	Associated with various cellular activities
CU118_RS04310	COG0671	phosphoesterase, PA-phosphatase related
CU118_RS04385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CU118_RS04405	COG0531	amino acid
CU118_RS04420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CU118_RS04425	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CU118_RS04440	COG0116	Belongs to the methyltransferase superfamily
CU118_RS04475	COG4499	WXG100 protein secretion system (Wss), protein YukC
CU118_RS04475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CU118_RS04485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CU118_RS04490	COG3935	DnaD domain protein
CU118_RS04515	COG0438	transferase activity, transferring glycosyl groups
CU118_RS04520	COG1694	Mazg nucleotide pyrophosphohydrolase
CU118_RS04525	COG2738	Putative neutral zinc metallopeptidase
CU118_RS04530	COG4347	Protein of unknown function (DUF1405)
CU118_RS04565	COG0142	geranyltranstransferase activity
CU118_RS04630	COG0492	ferredoxin-NADP+ reductase activity
CU118_RS04645	COG0514	ATP-dependent DNA helicase (RecQ)
CU118_RS04655	COG1141	Ferredoxin
CU118_RS04690	COG0860	N-Acetylmuramoyl-L-alanine amidase
CU118_RS04690	COG1388	LysM domain
CU118_RS04740	COG5280	Phage tail tape measure protein TP901
CU118_RS04740	COG3953	SLT domain
CU118_RS04865	COG0756	dUTP diphosphatase activity
CU118_RS04965	COG3646	Phage regulatory protein
CU118_RS04965	COG3645	SOS response
CU118_RS05005	COG0582	viral genome integration into host DNA
CU118_RS05020	COG5002	protein histidine kinase activity
CU118_RS05025	COG0745	RESPONSE REGULATOR receiver
CU118_RS05030	COG1187	pseudouridine synthase activity
CU118_RS05055	COG0735	belongs to the Fur family
CU118_RS05060	COG0494	nUDIX hydrolase
CU118_RS05065	COG0667	Aldo Keto reductase
CU118_RS05075	COG4221	oxidoreductase activity
CU118_RS05090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CU118_RS05100	COG0366	Alpha amylase catalytic
CU118_RS05105	COG1609	Transcriptional regulator
CU118_RS05120	COG2195	Cleaves the N-terminal amino acid of tripeptides
CU118_RS05130	COG4129	membrane
CU118_RS05140	COG0508	dehydrogenase complex catalyzes the overall conversion of
CU118_RS05145	COG0022	dehydrogenase e1 component
CU118_RS05150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CU118_RS05155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CU118_RS05160	COG0497	DNA recombination
CU118_RS05190	COG1302	Protein conserved in bacteria
CU118_RS05195	COG0439	Biotin carboxylase
CU118_RS05200	COG0511	ligase activity, forming carbon-carbon bonds
CU118_RS05210	COG0006	proline dipeptidase activity
CU118_RS05225	COG0095	Lipoate-protein ligase
CU118_RS05230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CU118_RS05275	COG4537	Required for transformation and DNA binding
CU118_RS05280	COG1459	type II secretion system
CU118_RS05285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CU118_RS05290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CU118_RS05295	COG0011	TIGRFAM Protein of
CU118_RS05300	COG1940	carbohydrate kinase activity
CU118_RS05305	COG4483	Protein conserved in bacteria
CU118_RS05315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CU118_RS05325	COG0768	penicillin binding
CU118_RS05340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU118_RS05345	COG1121	(ABC) transporter
CU118_RS05355	COG0513	Belongs to the DEAD box helicase family
CU118_RS05365	COG2384	SAM-dependent methyltransferase
CU118_RS05385	COG0517	IMP dehydrogenase activity
CU118_RS05405	COG0295	cytidine deaminase activity
CU118_RS05420	COG1702	phosphate starvation-inducible protein PhoH
CU118_RS05435	COG1030	water channel activity
CU118_RS05445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CU118_RS05450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CU118_RS05480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CU118_RS05505	COG1466	dna polymerase III delta subunit
CU118_RS05510	COG2333	competence protein COMEC
CU118_RS05510	COG0658	competence protein
CU118_RS05515	COG2131	deaminase
CU118_RS05525	COG2226	methyltransferase
CU118_RS05530	COG0799	negative regulation of ribosome biogenesis
CU118_RS05535	COG1713	HD superfamily hydrolase involved in NAD metabolism
CU118_RS05545	COG1534	Rna-binding protein
CU118_RS05555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CU118_RS05560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CU118_RS05580	COG3177	Filamentation induced by cAMP protein fic
CU118_RS05585	COG1914	H( )-stimulated, divalent metal cation uptake system
CU118_RS05595	COG0439	Biotin carboxylase
CU118_RS05600	COG0511	ligase activity, forming carbon-carbon bonds
CU118_RS05605	COG1984	allophanate hydrolase subunit 2
CU118_RS05610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CU118_RS05625	COG0826	peptidase U32
CU118_RS05630	COG0826	peptidase U32
CU118_RS05660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CU118_RS05680	COG1104	cysteine desulfurase activity
CU118_RS05685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU118_RS05695	COG3237	CsbD-like
CU118_RS05700	COG1959	2 iron, 2 sulfur cluster binding
CU118_RS05705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CU118_RS05710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CU118_RS05760	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CU118_RS05760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CU118_RS05765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CU118_RS05765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CU118_RS05770	COG1862	Preprotein translocase
CU118_RS05810	COG2868	ribosomal protein
CU118_RS05855	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CU118_RS05865	COG0285	dihydrofolate synthase activity
CU118_RS05875	COG2818	Glycosylase
CU118_RS05905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CU118_RS05940	COG4112	unkown
CU118_RS05965	COG0833	amino acid
CU118_RS05980	COG1484	DNA-dependent DNA replication
CU118_RS06010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CU118_RS06010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CU118_RS06020	COG5002	protein histidine kinase activity
CU118_RS06025	COG0745	RESPONSE REGULATOR receiver
CU118_RS06040	COG0372	Belongs to the citrate synthase family
CU118_RS06045	COG1113	amino acid transport
CU118_RS06070	COG0281	malic enzyme
CU118_RS06080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CU118_RS06085	COG4109	DRTGG domain
CU118_RS06130	COG0827	DNA restriction-modification system
CU118_RS06140	COG0730	response to heat
CU118_RS06150	COG1104	cysteine desulfurase activity
CU118_RS06165	COG1956	GAF domain-containing protein
CU118_RS06185	COG0584	glycerophosphoryl diester phosphodiesterase
CU118_RS06190	COG1764	response to oxidative stress
CU118_RS06195	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CU118_RS06200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CU118_RS06215	COG1263	PTS System
CU118_RS06215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU118_RS06220	COG0204	Acyl-transferase
CU118_RS06225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CU118_RS06255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CU118_RS06260	COG0454	-acetyltransferase
CU118_RS06280	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CU118_RS06280	COG1605	Chorismate mutase
CU118_RS06305	COG1674	ftsk spoiiie
CU118_RS06310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CU118_RS06320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CU118_RS06325	COG1363	Peptidase, m42
CU118_RS06335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CU118_RS06345	COG0510	thiamine kinase activity
CU118_RS06365	COG1187	pseudouridine synthase activity
CU118_RS06370	COG2244	polysaccharide biosynthetic process
CU118_RS06375	COG2081	HI0933 family
CU118_RS06395	COG2814	Major facilitator Superfamily
CU118_RS06400	COG1242	4 iron, 4 sulfur cluster binding
CU118_RS06405	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CU118_RS06420	COG2267	carboxylic ester hydrolase activity
CU118_RS06455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CU118_RS06455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CU118_RS06475	COG4193	domain, Protein
CU118_RS06475	COG3266	domain, Protein
CU118_RS06475	COG5632	N-Acetylmuramoyl-L-alanine amidase
CU118_RS06505	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CU118_RS06525	COG0656	L-ascorbic acid biosynthetic process
CU118_RS06550	COG1506	peptidase
CU118_RS06605	COG1131	(ABC) transporter
CU118_RS06660	COG5492	domain, Protein
CU118_RS06715	COG0860	N-Acetylmuramoyl-L-alanine amidase
CU118_RS06715	COG1388	LysM domain
CU118_RS06735	COG1388	LysM domain
CU118_RS06735	COG5632	N-Acetylmuramoyl-L-alanine amidase
CU118_RS06780	COG0739	heme binding
CU118_RS06830	COG0740	serine-type endopeptidase activity
CU118_RS07050	COG1131	(ABC) transporter
CU118_RS07160	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CU118_RS07190	COG1131	(ABC) transporter
CU118_RS07195	COG0537	adenosine 5'-monophosphoramidase activity
CU118_RS07225	COG0420	3'-5' exonuclease activity
CU118_RS07255	COG2197	response regulator
CU118_RS07260	COG2203	Gaf domain
CU118_RS07260	COG4585	Histidine kinase
CU118_RS07265	COG0564	pseudouridine synthase activity
CU118_RS07305	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CU118_RS07310	COG1126	abc transporter atp-binding protein
CU118_RS07315	COG0765	amino acid transport
CU118_RS07475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CU118_RS07480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CU118_RS07490	COG4129	membrane
CU118_RS07510	COG1194	a g-specific adenine glycosylase
CU118_RS07515	COG1988	membrane-bound metal-dependent
CU118_RS07530	COG1134	teichoic acid transport
CU118_RS07530	COG1388	LysM domain
CU118_RS07560	COG0535	radical SAM domain protein
CU118_RS07565	COG1607	acyl-coa hydrolase
CU118_RS07570	COG2309	aminopeptidase activity
CU118_RS07590	COG1295	ribonuclease BN
CU118_RS07730	COG4851	CamS sex pheromone cAM373 precursor
CU118_RS07750	COG4496	protein, YerC YecD
CU118_RS07790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CU118_RS07800	COG0077	Prephenate dehydratase
CU118_RS07820	COG1335	isochorismatase
CU118_RS07835	COG1012	belongs to the aldehyde dehydrogenase family
CU118_RS07885	COG1131	(ABC) transporter
CU118_RS07900	COG1725	Transcriptional regulator
CU118_RS07945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CU118_RS07950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CU118_RS07955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CU118_RS08020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU118_RS08025	COG1621	beta-fructofuranosidase activity
CU118_RS08030	COG1609	Transcriptional regulator
CU118_RS08035	COG0004	ammonium transporteR
CU118_RS08040	COG0425	Belongs to the sulfur carrier protein TusA family
CU118_RS08045	COG2391	methyltransferase activity
CU118_RS08055	COG0488	(ABC) transporter
CU118_RS08065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CU118_RS08075	COG0456	acetyltransferase
CU118_RS08080	COG1214	PFAM Peptidase M22, glycoprotease
CU118_RS08085	COG0802	atpase or kinase
CU118_RS08100	COG0028	Belongs to the TPP enzyme family
CU118_RS08175	COG2183	response to ionizing radiation
CU118_RS08180	COG1191	sigma factor activity
CU118_RS08190	COG1366	Belongs to the anti-sigma-factor antagonist family
CU118_RS08195	COG2208	phosphoserine phosphatase activity
CU118_RS08260	COG2205	protein histidine kinase activity
CU118_RS08265	COG0745	RESPONSE REGULATOR receiver
CU118_RS08275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CU118_RS08285	COG0772	Belongs to the SEDS family
CU118_RS08300	COG1937	Protein conserved in bacteria
CU118_RS08310	COG1418	mRNA catabolic process
CU118_RS08355	COG0629	single-stranded DNA binding
CU118_RS08435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CU118_RS08460	COG0009	L-threonylcarbamoyladenylate synthase
CU118_RS08465	COG2890	protein-(glutamine-N5) methyltransferase activity
CU118_RS08490	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CU118_RS08530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU118_RS08580	COG0813	purine-nucleoside phosphorylase activity
CU118_RS08585	COG0783	Belongs to the Dps family
CU118_RS08605	COG1482	cell wall glycoprotein biosynthetic process
CU118_RS08610	COG0702	epimerase
CU118_RS08615	COG0640	Transcriptional regulator
CU118_RS08635	COG0561	phosphatase activity
CU118_RS08640	COG1119	ATPase activity
CU118_RS08655	COG3711	transcriptional antiterminator
CU118_RS08685	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CU118_RS08745	COG0489	protein tyrosine kinase activity
CU118_RS08750	COG2814	Major facilitator Superfamily
CU118_RS08765	COG1272	protein, Hemolysin III
CU118_RS08775	COG1988	membrane-bound metal-dependent
CU118_RS08785	COG3314	Sporulation integral membrane protein YlbJ
CU118_RS08790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU118_RS08795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU118_RS08800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CU118_RS08805	COG3457	Alanine racemase
CU118_RS08810	COG4264	IucA IucC family
CU118_RS08815	COG2814	Major facilitator Superfamily
CU118_RS08845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU118_RS08855	COG2130	NADP-dependent
CU118_RS08915	COG0438	transferase activity, transferring glycosyl groups
CU118_RS08950	COG0210	DNA helicase
CU118_RS08955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CU118_RS08975	COG3527	Alpha-acetolactate decarboxylase
CU118_RS08980	COG0028	Belongs to the TPP enzyme family
CU118_RS09055	COG0201	protein transport
CU118_RS09170	COG2252	PERMEase
CU118_RS09215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU118_RS09280	COG1763	Mo-molybdopterin cofactor biosynthetic process
CU118_RS09300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CU118_RS09305	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CU118_RS09310	COG4149	molybdate abc transporter
CU118_RS09315	COG0725	ABC transporter, periplasmic molybdate-binding protein
CU118_RS09330	COG1268	BioY protein
CU118_RS09345	COG1960	acyl-CoA dehydrogenase activity
CU118_RS09350	COG4413	Urea transporter
CU118_RS09425	COG1757	Na H antiporter
CU118_RS09440	COG3942	CHAP domain
CU118_RS09495	COG1266	CAAX protease self-immunity
CU118_RS09510	COG1113	amino acid transport
CU118_RS09530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU118_RS09535	COG0385	Bile acid
CU118_RS09545	COG1263	PTS System
CU118_RS09545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU118_RS09550	COG1737	Transcriptional regulator
CU118_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
CU118_RS09575	COG1473	amidohydrolase
CU118_RS09590	COG0583	DNA-binding transcription factor activity
CU118_RS09610	COG2258	MOSC domain
CU118_RS09630	COG1668	transmembrane transport
CU118_RS09635	COG4152	abc transporter atp-binding protein
CU118_RS09640	COG3152	Membrane
CU118_RS09650	COG0786	glutamate:sodium symporter activity
CU118_RS09660	COG0598	Magnesium transport protein CorA
CU118_RS09675	COG0657	acetylesterase activity
CU118_RS09685	COG2814	Major facilitator Superfamily
CU118_RS09690	COG1566	PFAM secretion protein HlyD family protein
CU118_RS09700	COG2814	Major facilitator Superfamily
CU118_RS09765	COG1131	(ABC) transporter
CU118_RS09780	COG1620	l-lactate permease
CU118_RS09800	COG0604	alcohol dehydrogenase
CU118_RS09830	COG1511	domain protein
CU118_RS09845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU118_RS09845	COG1263	PTS System
CU118_RS09860	COG3871	stress protein (general stress protein 26)
CU118_RS09900	COG0789	Transcriptional regulator
CU118_RS09920	COG2181	nitrate reductase activity
CU118_RS09930	COG1140	nitrate reductase beta subunit
CU118_RS09935	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CU118_RS09945	COG2146	nitrite reductase [NAD(P)H] activity
CU118_RS09950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CU118_RS09960	COG0454	-acetyltransferase
CU118_RS09970	COG2116	formate transmembrane transporter activity
CU118_RS09985	COG3443	Belongs to the bacterial solute-binding protein 9 family
CU118_RS09985	COG0803	Belongs to the bacterial solute-binding protein 9 family
CU118_RS10020	COG1126	abc transporter atp-binding protein
CU118_RS10025	COG0765	amino acid transport
CU118_RS10030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU118_RS10035	COG2814	Major facilitator Superfamily
CU118_RS10055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CU118_RS10100	COG0156	8-amino-7-oxononanoate synthase activity
CU118_RS10110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CU118_RS10115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CU118_RS10140	COG1929	Belongs to the glycerate kinase type-1 family
CU118_RS10150	COG2814	Major facilitator Superfamily
CU118_RS10170	COG1113	amino acid transport
CU118_RS10185	COG0531	amino acid
CU118_RS10210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CU118_RS10220	COG1174	glycine betaine transport
CU118_RS10230	COG1174	glycine betaine transport
CU118_RS10250	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CU118_RS10255	COG0531	amino acid
CU118_RS10260	COG2272	Belongs to the type-B carboxylesterase lipase family
CU118_RS10265	COG2814	Major facilitator Superfamily
CU118_RS10270	COG0390	transport system, permease component
CU118_RS10275	COG4619	ABC transporter
CU118_RS10280	COG1363	Peptidase, m42
CU118_RS10300	COG4808	Protein conserved in bacteria
CU118_RS10305	COG0069	glutamate synthase activity
CU118_RS10320	COG1124	(ABC) transporter
CU118_RS10330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU118_RS10335	COG0601	transmembrane transport
CU118_RS10340	COG0747	negative chemotaxis
CU118_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
CU118_RS10375	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CU118_RS10380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CU118_RS10455	COG0494	nUDIX hydrolase
CU118_RS10510	COG1070	Carbohydrate kinase
CU118_RS10515	COG1802	Transcriptional regulator
CU118_RS10520	COG0789	Transcriptional regulator
CU118_RS10525	COG2357	RelA SpoT domain protein
CU118_RS10530	COG4876	unkown
CU118_RS10545	COG2271	Major facilitator Superfamily
CU118_RS10550	COG0586	Pfam SNARE associated Golgi protein
CU118_RS10560	COG2814	Major facilitator Superfamily
CU118_RS10565	COG1846	Transcriptional regulator
CU118_RS10580	COG1131	(ABC) transporter
CU118_RS10600	COG0400	carboxylic ester hydrolase activity
CU118_RS10605	COG0346	lactoylglutathione lyase activity
CU118_RS10610	COG1846	Transcriptional regulator
CU118_RS10620	COG2514	catechol 2,3-dioxygenase activity
CU118_RS10635	COG0561	phosphatase activity
CU118_RS10640	COG1131	(ABC) transporter
CU118_RS10650	COG3764	Sortase (surface protein transpeptidase)
CU118_RS10670	COG1760	l-serine dehydratase
CU118_RS10675	COG1760	l-serine dehydratase
CU118_RS10690	COG0697	spore germination
CU118_RS10720	COG0028	Belongs to the TPP enzyme family
CU118_RS10735	COG0583	DNA-binding transcription factor activity
CU118_RS10745	COG3942	CHAP domain
CU118_RS10755	COG3425	synthase
CU118_RS10760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CU118_RS10790	COG2409	Drug exporters of the RND superfamily
CU118_RS10835	COG0436	Aminotransferase
CU118_RS10915	COG0596	Alpha beta hydrolase
CU118_RS10950	COG3001	Fructosamine kinase
CU118_RS10955	COG0167	dihydroorotate dehydrogenase activity
CU118_RS11015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CU118_RS11020	COG3527	Alpha-acetolactate decarboxylase
CU118_RS11035	COG0531	amino acid
CU118_RS11065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CU118_RS11085	COG1012	belongs to the aldehyde dehydrogenase family
CU118_RS11095	COG1510	regulation of RNA biosynthetic process
CU118_RS11100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU118_RS11125	COG2851	Citrate transporter
CU118_RS11135	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CU118_RS11145	COG0386	Belongs to the glutathione peroxidase family
CU118_RS11165	COG1136	(ABC) transporter
CU118_RS11170	COG2205	protein histidine kinase activity
CU118_RS11175	COG0745	RESPONSE REGULATOR receiver
CU118_RS11185	COG1785	Belongs to the alkaline phosphatase family
CU118_RS11195	COG1846	Transcriptional regulator
CU118_RS11240	COG1438	arginine binding
CU118_RS11260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU118_RS11260	COG3711	transcriptional antiterminator
CU118_RS11265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU118_RS11265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU118_RS11265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU118_RS11270	COG1482	cell wall glycoprotein biosynthetic process
CU118_RS11280	COG1705	Flagellar rod assembly protein muramidase FlgJ
CU118_RS11280	COG3942	CHAP domain
CU118_RS11285	COG3433	isochorismatase activity
CU118_RS11285	COG1535	isochorismatase
CU118_RS11300	COG0438	transferase activity, transferring glycosyl groups
CU118_RS11315	COG1073	alpha beta
CU118_RS11335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CU118_RS11365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CU118_RS11465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CU118_RS11535	COG0471	metal ion transport
CU118_RS11540	COG2962	Rard protein
CU118_RS11550	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CU118_RS11565	COG1136	(ABC) transporter
CU118_RS11570	COG0577	efflux transmembrane transporter activity
CU118_RS11585	COG1278	Cold shock
CU118_RS11605	COG1475	DNA binding
CU118_RS11645	COG2501	S4 domain
CU118_RS11660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CU118_RS11665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CU118_RS11695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CU118_RS11705	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CU118_RS11715	COG0305	Participates in initiation and elongation during chromosome replication
CU118_RS11750	COG4863	YycH protein
CU118_RS11760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CU118_RS11765	COG0737	Belongs to the 5'-nucleotidase family
CU118_RS11780	COG1396	sequence-specific DNA binding
CU118_RS11790	COG1196	nuclear chromosome segregation
CU118_RS11865	COG0456	acetyltransferase
CU118_RS11900	COG2030	dehydratase
CU118_RS11905	COG0584	glycerophosphoryl diester phosphodiesterase
CU118_RS11915	COG3425	synthase
CU118_RS11980	COG0823	Involved in the tonB-independent uptake of proteins
CU118_RS11995	COG1473	amidohydrolase
CU118_RS12005	COG1283	sodium-dependent phosphate transmembrane transporter activity
CU118_RS12010	COG4716	Myosin-crossreactive antigen
CU118_RS12020	COG1620	l-lactate permease
CU118_RS12040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU118_RS12045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU118_RS12050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CU118_RS12060	COG2423	ornithine cyclodeaminase activity
CU118_RS12065	COG4264	IucA IucC family
CU118_RS12070	COG2814	Major facilitator Superfamily
CU118_RS12075	COG4264	IucA IucC family
CU118_RS12080	COG4264	IucA IucC family
CU118_RS12090	COG0019	diaminopimelate decarboxylase activity
CU118_RS12095	COG1475	DNA binding
CU118_RS12120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CU118_RS12125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CU118_RS12130	COG0438	transferase activity, transferring glycosyl groups
CU118_RS12165	COG0813	purine-nucleoside phosphorylase activity
CU118_RS12170	COG2814	Major facilitator Superfamily
CU118_RS12190	COG3639	organic phosphonate transmembrane transporter activity
CU118_RS12210	COG0737	Belongs to the 5'-nucleotidase family
CU118_RS12220	COG1454	alcohol dehydrogenase
CU118_RS12220	COG1012	belongs to the aldehyde dehydrogenase family
CU118_RS12245	COG1086	Polysaccharide biosynthesis protein
CU118_RS12255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CU118_RS12285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CU118_RS12295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CU118_RS12300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CU118_RS12310	COG2832	Protein of unknown function (DUF454)
CU118_RS12350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CU118_RS12355	COG1960	acyl-CoA dehydrogenase activity
CU118_RS12375	COG3477	response to acidic pH
CU118_RS12400	COG1114	Component of the transport system for branched-chain amino acids
CU118_RS12405	COG1335	isochorismatase
CU118_RS12410	COG3961	Belongs to the TPP enzyme family
CU118_RS12440	COG1737	Transcriptional regulator
CU118_RS12475	COG0601	transmembrane transport
CU118_RS12480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU118_RS12490	COG0405	Gamma-glutamyltransferase
CU118_RS12510	COG3842	ATPase activity
CU118_RS12520	COG1175	transmembrane transport
CU118_RS12525	COG3833	ABC-type maltose transport systems, permease component
CU118_RS12530	COG0673	inositol 2-dehydrogenase activity
CU118_RS12535	COG0673	inositol 2-dehydrogenase activity
CU118_RS12545	COG1755	Isoprenylcysteine carboxyl methyltransferase
CU118_RS12600	COG0183	Belongs to the thiolase family
CU118_RS12610	COG1960	acyl-CoA dehydrogenase activity
CU118_RS12615	COG0318	PFAM AMP-dependent synthetase and ligase
CU118_RS12630	COG0747	negative chemotaxis
CU118_RS12635	COG3189	MarR family transcriptional regulator
CU118_RS12670	COG1263	PTS System
CU118_RS12670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU118_RS12670	COG2190	(PTS) system
CU118_RS12675	COG1957	nucleoside hydrolase
CU118_RS12695	COG3414	Phosphotransferase system galactitol-specific IIB component
CU118_RS12700	COG3775	system Galactitol-specific IIC component
CU118_RS12705	COG1063	alcohol dehydrogenase
CU118_RS12715	COG1063	alcohol dehydrogenase
CU118_RS12725	COG1063	alcohol dehydrogenase
CU118_RS12730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CU118_RS12735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CU118_RS12745	COG1063	alcohol dehydrogenase
CU118_RS12750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CU118_RS12785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU118_RS12800	COG2723	6-phospho-beta-galactosidase activity
CU118_RS12805	COG2226	methyltransferase
CU118_RS12855	COG1131	(ABC) transporter
CU118_RS12875	COG1388	LysM domain
CU118_RS12875	COG3942	CHAP domain
CU118_RS13020	COG1114	Component of the transport system for branched-chain amino acids
CU118_RS13030	COG2318	DinB family
CU118_RS13035	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CU118_RS13045	COG0577	efflux transmembrane transporter activity
CU118_RS13075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU118_RS13080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CU118_RS13105	COG3314	Sporulation integral membrane protein YlbJ
CU118_RS13130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU118_RS13155	COG3037	sugar-specific permease SgaT UlaA
CU118_RS13165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU118_RS13170	COG3711	transcriptional antiterminator
CU118_RS13195	COG2271	Major facilitator Superfamily
CU118_RS13200	COG0346	lactoylglutathione lyase activity
CU118_RS13205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU118_RS13210	COG0431	NADPH-dependent FMN reductase
CU118_RS13230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU118_RS13235	COG2822	iron ion transport
CU118_RS13245	COG0672	)-iron permease
CU118_RS13250	COG0805	protein transport
CU118_RS13255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CU118_RS13265	COG1476	TRANSCRIPTIONal
CU118_RS13275	COG1131	(ABC) transporter
CU118_RS13300	COG0646	methionine synthase
CU118_RS13300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CU118_RS13305	COG0626	cystathionine gamma-synthase activity
CU118_RS13310	COG0626	cystathionine gamma-synthase activity
CU118_RS13320	COG1475	DNA binding
CU118_RS13325	COG0668	transmembrane transport
CU118_RS13330	COG4481	Protein conserved in bacteria
CU118_RS13335	COG0012	GTP binding
CU118_RS13435	COG1823	symporter activity
CU118_RS13465	COG2233	PERMEase
CU118_RS13485	COG3759	membrane
CU118_RS13615	COG0523	cobalamin synthesis protein
CU118_RS13640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CU118_RS13650	COG5609	conserved protein (DUF2294)
CU118_RS13665	COG1647	Serine aminopeptidase, S33
CU118_RS13670	COG0733	neurotransmitter:sodium symporter activity
CU118_RS13675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CU118_RS13680	COG0626	cystathionine gamma-synthase activity
CU118_RS13690	COG2011	ABC-type metal ion transport system permease component
CU118_RS13695	COG1464	Belongs to the NlpA lipoprotein family
CU118_RS13715	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CU118_RS13730	COG0583	DNA-binding transcription factor activity
CU118_RS13735	COG0067	glutamate synthase
CU118_RS13735	COG0070	glutamate synthase
CU118_RS13735	COG0069	glutamate synthase activity
CU118_RS13740	COG0493	'glutamate synthase
CU118_RS13750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU118_RS13750	COG1263	PTS System
CU118_RS13755	COG0366	Alpha amylase catalytic
CU118_RS13760	COG2188	Transcriptional regulator
CU118_RS13780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CU118_RS13815	COG1982	Orn Lys Arg decarboxylase major
CU118_RS13825	COG3870	Protein conserved in bacteria
CU118_RS13830	COG0470	DNA polymerase III
CU118_RS13835	COG1774	PSP1 C-terminal conserved region
CU118_RS13845	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CU118_RS13855	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CU118_RS13865	COG0084	hydrolase, TatD family'
CU118_RS13870	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CU118_RS13880	COG4466	Protein conserved in bacteria
CU118_RS13890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CU118_RS13895	COG0251	oxidation-reduction process
CU118_RS13940	COG2244	polysaccharide biosynthetic process
CU118_RS13945	COG3956	TIGRFAM MazG family protein
CU118_RS13950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CU118_RS13960	COG1098	S1 RNA binding domain
CU118_RS13975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CU118_RS14000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CU118_RS14135	COG1136	(ABC) transporter
CU118_RS14135	COG0577	efflux transmembrane transporter activity
CU118_RS14175	COG3682	Transcriptional regulator