locus-tag	class	description
CSC50_RS00010	COG3682	Transcriptional regulator
CSC50_RS00030	COG0604	alcohol dehydrogenase
CSC50_RS00230	COG1396	sequence-specific DNA binding
CSC50_RS00265	COG0822	iron-sulfur transferase activity
CSC50_RS00275	COG0719	Fe-S assembly protein
CSC50_RS00280	COG0396	ATPase activity
CSC50_RS00295	COG1464	Belongs to the NlpA lipoprotein family
CSC50_RS00300	COG2011	ABC-type metal ion transport system permease component
CSC50_RS00315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CSC50_RS00325	COG3878	Protein conserved in bacteria
CSC50_RS00340	COG1393	Belongs to the ArsC family
CSC50_RS00345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSC50_RS00370	COG1279	arginine transmembrane transporter activity
CSC50_RS00375	COG0406	alpha-ribazole phosphatase activity
CSC50_RS00415	COG1278	Cold shock
CSC50_RS00490	COG0557	exoribonuclease II activity
CSC50_RS00495	COG1647	Serine aminopeptidase, S33
CSC50_RS00500	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSC50_RS00565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CSC50_RS00620	COG1388	LysM domain
CSC50_RS00620	COG3942	CHAP domain
CSC50_RS00650	COG1040	competence protein
CSC50_RS00655	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CSC50_RS00665	COG1739	Uncharacterized protein family UPF0029
CSC50_RS00670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSC50_RS00725	COG4607	ABC-type enterochelin transport system periplasmic component
CSC50_RS00730	COG4604	ABC transporter, ATP-binding protein
CSC50_RS00735	COG4605	iron ion homeostasis
CSC50_RS00740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC50_RS00750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC50_RS00755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC50_RS00785	COG3104	oligopeptide transport
CSC50_RS00820	COG1174	glycine betaine transport
CSC50_RS00825	COG1125	glycine betaine transport
CSC50_RS00825	COG0517	IMP dehydrogenase activity
CSC50_RS00830	COG0514	ATP-dependent DNA helicase (RecQ)
CSC50_RS00835	COG0488	(ABC) transporter
CSC50_RS00865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSC50_RS00870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSC50_RS00870	COG0512	Glutamine amidotransferase of anthranilate synthase
CSC50_RS00880	COG0720	synthase
CSC50_RS00915	COG0463	Glycosyl transferase, family 2
CSC50_RS00920	COG0656	L-ascorbic acid biosynthetic process
CSC50_RS00925	COG1253	flavin adenine dinucleotide binding
CSC50_RS00930	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CSC50_RS00935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC50_RS00935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC50_RS00935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC50_RS00940	COG1105	Belongs to the carbohydrate kinase PfkB family
CSC50_RS00945	COG1349	DNA-binding transcription factor activity
CSC50_RS00950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSC50_RS00980	COG0415	Belongs to the DNA photolyase family
CSC50_RS00985	COG0471	metal ion transport
CSC50_RS00995	COG4989	oxidoreductase activity
CSC50_RS01000	COG0523	cobalamin synthesis protein
CSC50_RS01010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CSC50_RS01015	COG4988	ABC transporter
CSC50_RS01035	COG1611	Belongs to the LOG family
CSC50_RS01065	COG2839	Protein conserved in bacteria
CSC50_RS01070	COG2814	Major facilitator Superfamily
CSC50_RS01075	COG0583	DNA-binding transcription factor activity
CSC50_RS01105	COG1917	Cupin 2, conserved barrel domain protein
CSC50_RS01105	COG4977	sequence-specific DNA binding
CSC50_RS01115	COG3942	CHAP domain
CSC50_RS01115	COG1388	LysM domain
CSC50_RS01120	COG0306	phosphate transporter
CSC50_RS01125	COG1392	Phosphate transport regulator
CSC50_RS01130	COG0577	efflux transmembrane transporter activity
CSC50_RS01135	COG1136	(ABC) transporter
CSC50_RS01150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC50_RS01175	COG3949	Membrane
CSC50_RS01185	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CSC50_RS01195	COG2376	Dihydroxyacetone kinase
CSC50_RS01200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC50_RS01205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC50_RS01210	COG1120	ATPase activity
CSC50_RS01215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSC50_RS01225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC50_RS01230	COG1132	(ABC) transporter
CSC50_RS01235	COG1686	Belongs to the peptidase S11 family
CSC50_RS01240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CSC50_RS01250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CSC50_RS01255	COG1682	transport, permease protein
CSC50_RS01265	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CSC50_RS01275	COG1321	iron dependent repressor
CSC50_RS01280	COG1121	(ABC) transporter
CSC50_RS01285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC50_RS01290	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSC50_RS01345	COG4974	Belongs to the 'phage' integrase family
CSC50_RS01395	COG4139	cobalamin transport
CSC50_RS01400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSC50_RS01435	COG1078	dGTPase activity
CSC50_RS01445	COG0655	NAD(P)H dehydrogenase (quinone) activity
CSC50_RS01455	COG0667	Aldo Keto reductase
CSC50_RS01490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSC50_RS01510	COG0083	homoserine kinase activity
CSC50_RS01515	COG0095	Lipoate-protein ligase
CSC50_RS01615	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CSC50_RS01630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CSC50_RS01675	COG0561	phosphatase activity
CSC50_RS01685	COG1428	Deoxynucleoside kinase
CSC50_RS01690	COG1428	Deoxynucleoside kinase
CSC50_RS01695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSC50_RS01725	COG1473	amidohydrolase
CSC50_RS01765	COG2813	Specifically methylates the guanine in position
CSC50_RS01825	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CSC50_RS01850	COG4956	integral membrane protein (PIN domain superfamily)
CSC50_RS01855	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSC50_RS01870	COG3880	PFAM UvrB UvrC protein
CSC50_RS01880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC50_RS01895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC50_RS01990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSC50_RS02015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSC50_RS02030	COG1098	S1 RNA binding domain
CSC50_RS02040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSC50_RS02045	COG3956	TIGRFAM MazG family protein
CSC50_RS02050	COG2244	polysaccharide biosynthetic process
CSC50_RS02095	COG0251	oxidation-reduction process
CSC50_RS02100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CSC50_RS02110	COG4466	Protein conserved in bacteria
CSC50_RS02120	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CSC50_RS02125	COG0084	hydrolase, TatD family'
CSC50_RS02135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSC50_RS02145	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CSC50_RS02155	COG1774	PSP1 C-terminal conserved region
CSC50_RS02160	COG0470	DNA polymerase III
CSC50_RS02165	COG3870	Protein conserved in bacteria
CSC50_RS02175	COG1982	Orn Lys Arg decarboxylase major
CSC50_RS02215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSC50_RS02235	COG2188	Transcriptional regulator
CSC50_RS02240	COG0366	Alpha amylase catalytic
CSC50_RS02245	COG1263	PTS System
CSC50_RS02245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC50_RS02255	COG0493	'glutamate synthase
CSC50_RS02260	COG0070	glutamate synthase
CSC50_RS02260	COG0069	glutamate synthase activity
CSC50_RS02260	COG0067	glutamate synthase
CSC50_RS02265	COG0583	DNA-binding transcription factor activity
CSC50_RS02300	COG1464	Belongs to the NlpA lipoprotein family
CSC50_RS02305	COG2011	ABC-type metal ion transport system permease component
CSC50_RS02315	COG0626	cystathionine gamma-synthase activity
CSC50_RS02320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSC50_RS02325	COG0733	neurotransmitter:sodium symporter activity
CSC50_RS02330	COG1647	Serine aminopeptidase, S33
CSC50_RS02345	COG5609	conserved protein (DUF2294)
CSC50_RS02355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSC50_RS02380	COG0523	cobalamin synthesis protein
CSC50_RS02540	COG3759	membrane
CSC50_RS02580	COG2233	PERMEase
CSC50_RS02615	COG1823	symporter activity
CSC50_RS02720	COG0012	GTP binding
CSC50_RS02725	COG4481	Protein conserved in bacteria
CSC50_RS02730	COG0668	transmembrane transport
CSC50_RS02735	COG1475	DNA binding
CSC50_RS02745	COG0626	cystathionine gamma-synthase activity
CSC50_RS02750	COG0626	cystathionine gamma-synthase activity
CSC50_RS02755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSC50_RS02755	COG0646	methionine synthase
CSC50_RS02785	COG1131	(ABC) transporter
CSC50_RS02795	COG1476	TRANSCRIPTIONal
CSC50_RS02805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSC50_RS02810	COG0805	protein transport
CSC50_RS02815	COG0672	)-iron permease
CSC50_RS02825	COG2822	iron ion transport
CSC50_RS02830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC50_RS02845	COG0431	NADPH-dependent FMN reductase
CSC50_RS02850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC50_RS02855	COG0346	lactoylglutathione lyase activity
CSC50_RS02860	COG2271	Major facilitator Superfamily
CSC50_RS02885	COG3711	transcriptional antiterminator
CSC50_RS02890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC50_RS02900	COG3037	sugar-specific permease SgaT UlaA
CSC50_RS02930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC50_RS02955	COG3314	Sporulation integral membrane protein YlbJ
CSC50_RS02980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSC50_RS02985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC50_RS03015	COG0577	efflux transmembrane transporter activity
CSC50_RS03025	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CSC50_RS03035	COG1114	Component of the transport system for branched-chain amino acids
CSC50_RS03155	COG1388	LysM domain
CSC50_RS03155	COG3942	CHAP domain
CSC50_RS03175	COG1131	(ABC) transporter
CSC50_RS03230	COG2226	methyltransferase
CSC50_RS03240	COG2723	6-phospho-beta-galactosidase activity
CSC50_RS03245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC50_RS03245	COG1263	PTS System
CSC50_RS03245	COG2190	(PTS) system
CSC50_RS03255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC50_RS03290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CSC50_RS03295	COG1063	alcohol dehydrogenase
CSC50_RS03305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CSC50_RS03310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CSC50_RS03315	COG1063	alcohol dehydrogenase
CSC50_RS03325	COG1063	alcohol dehydrogenase
CSC50_RS03335	COG1063	alcohol dehydrogenase
CSC50_RS03340	COG3775	system Galactitol-specific IIC component
CSC50_RS03345	COG3414	Phosphotransferase system galactitol-specific IIB component
CSC50_RS03365	COG1957	nucleoside hydrolase
CSC50_RS03370	COG1263	PTS System
CSC50_RS03370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC50_RS03370	COG2190	(PTS) system
CSC50_RS03405	COG3189	MarR family transcriptional regulator
CSC50_RS03410	COG0747	negative chemotaxis
CSC50_RS03425	COG0318	PFAM AMP-dependent synthetase and ligase
CSC50_RS03430	COG1960	acyl-CoA dehydrogenase activity
CSC50_RS03440	COG0183	Belongs to the thiolase family
CSC50_RS03495	COG1755	Isoprenylcysteine carboxyl methyltransferase
CSC50_RS03505	COG0673	inositol 2-dehydrogenase activity
CSC50_RS03510	COG0673	inositol 2-dehydrogenase activity
CSC50_RS03515	COG3833	ABC-type maltose transport systems, permease component
CSC50_RS03520	COG1175	transmembrane transport
CSC50_RS03530	COG3842	ATPase activity
CSC50_RS03550	COG0405	Gamma-glutamyltransferase
CSC50_RS03560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC50_RS03565	COG0601	transmembrane transport
CSC50_RS03580	COG1131	(ABC) transporter
CSC50_RS03600	COG1136	(ABC) transporter
CSC50_RS03600	COG0577	efflux transmembrane transporter activity
CSC50_RS03605	COG1136	(ABC) transporter
CSC50_RS03630	COG1737	Transcriptional regulator
CSC50_RS03660	COG3961	Belongs to the TPP enzyme family
CSC50_RS03665	COG1335	isochorismatase
CSC50_RS03670	COG1114	Component of the transport system for branched-chain amino acids
CSC50_RS03720	COG5609	conserved protein (DUF2294)
CSC50_RS03725	COG1960	acyl-CoA dehydrogenase activity
CSC50_RS03730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC50_RS03765	COG2832	Protein of unknown function (DUF454)
CSC50_RS03775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSC50_RS03780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSC50_RS03790	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSC50_RS03820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSC50_RS03830	COG1086	Polysaccharide biosynthesis protein
CSC50_RS03855	COG1454	alcohol dehydrogenase
CSC50_RS03855	COG1012	belongs to the aldehyde dehydrogenase family
CSC50_RS03870	COG0737	Belongs to the 5'-nucleotidase family
CSC50_RS03890	COG3639	organic phosphonate transmembrane transporter activity
CSC50_RS03910	COG2814	Major facilitator Superfamily
CSC50_RS03915	COG0813	purine-nucleoside phosphorylase activity
CSC50_RS03950	COG0438	transferase activity, transferring glycosyl groups
CSC50_RS03955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSC50_RS03960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC50_RS03985	COG1475	DNA binding
CSC50_RS03990	COG0019	diaminopimelate decarboxylase activity
CSC50_RS04000	COG4264	IucA IucC family
CSC50_RS04005	COG4264	IucA IucC family
CSC50_RS04010	COG2814	Major facilitator Superfamily
CSC50_RS04015	COG4264	IucA IucC family
CSC50_RS04020	COG2423	ornithine cyclodeaminase activity
CSC50_RS04030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSC50_RS04035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC50_RS04040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC50_RS04060	COG1620	l-lactate permease
CSC50_RS04075	COG0697	spore germination
CSC50_RS04080	COG4716	Myosin-crossreactive antigen
CSC50_RS04085	COG1283	sodium-dependent phosphate transmembrane transporter activity
CSC50_RS04095	COG1473	amidohydrolase
CSC50_RS04130	COG0823	Involved in the tonB-independent uptake of proteins
CSC50_RS04185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC50_RS04190	COG2210	Belongs to the sulfur carrier protein TusA family
CSC50_RS04195	COG1937	Protein conserved in bacteria
CSC50_RS04200	COG0730	response to heat
CSC50_RS04275	COG2205	protein histidine kinase activity
CSC50_RS04280	COG0745	RESPONSE REGULATOR receiver
CSC50_RS04335	COG2003	Belongs to the UPF0758 family
CSC50_RS04375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSC50_RS04385	COG0730	response to heat
CSC50_RS04390	COG1937	Protein conserved in bacteria
CSC50_RS04395	COG2210	Belongs to the sulfur carrier protein TusA family
CSC50_RS04400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC50_RS04410	COG1846	Transcriptional regulator
CSC50_RS04410	COG1940	carbohydrate kinase activity
CSC50_RS04435	COG2030	dehydratase
CSC50_RS04440	COG0584	glycerophosphoryl diester phosphodiesterase
CSC50_RS04495	COG0737	Belongs to the 5'-nucleotidase family
CSC50_RS04500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CSC50_RS04510	COG4863	YycH protein
CSC50_RS04545	COG0305	Participates in initiation and elongation during chromosome replication
CSC50_RS04555	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CSC50_RS04565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSC50_RS04595	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSC50_RS04615	COG2501	S4 domain
CSC50_RS04655	COG1475	DNA binding
CSC50_RS04680	COG1278	Cold shock
CSC50_RS04690	COG0577	efflux transmembrane transporter activity
CSC50_RS04695	COG1136	(ABC) transporter
CSC50_RS04710	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CSC50_RS04720	COG2962	Rard protein
CSC50_RS04725	COG0471	metal ion transport
CSC50_RS04810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CSC50_RS04905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC50_RS04925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC50_RS04945	COG1073	alpha beta
CSC50_RS04960	COG0438	transferase activity, transferring glycosyl groups
CSC50_RS04975	COG3433	isochorismatase activity
CSC50_RS04975	COG1535	isochorismatase
CSC50_RS04980	COG3942	CHAP domain
CSC50_RS04980	COG1705	Flagellar rod assembly protein muramidase FlgJ
CSC50_RS04990	COG1482	cell wall glycoprotein biosynthetic process
CSC50_RS04995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC50_RS04995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC50_RS04995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC50_RS05000	COG3711	transcriptional antiterminator
CSC50_RS05000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC50_RS05020	COG1438	arginine binding
CSC50_RS05065	COG1846	Transcriptional regulator
CSC50_RS05075	COG1785	Belongs to the alkaline phosphatase family
CSC50_RS05085	COG0745	RESPONSE REGULATOR receiver
CSC50_RS05090	COG2205	protein histidine kinase activity
CSC50_RS05095	COG1136	(ABC) transporter
CSC50_RS05120	COG0386	Belongs to the glutathione peroxidase family
CSC50_RS05130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CSC50_RS05145	COG2851	Citrate transporter
CSC50_RS05170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC50_RS05175	COG1510	regulation of RNA biosynthetic process
CSC50_RS05185	COG1012	belongs to the aldehyde dehydrogenase family
CSC50_RS05205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSC50_RS05235	COG0531	amino acid
CSC50_RS05250	COG3527	Alpha-acetolactate decarboxylase
CSC50_RS05255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSC50_RS05315	COG0167	dihydroorotate dehydrogenase activity
CSC50_RS05320	COG3001	Fructosamine kinase
CSC50_RS05430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CSC50_RS05430	COG2755	lipolytic protein G-D-S-L family
CSC50_RS05435	COG3942	CHAP domain
CSC50_RS05465	COG0436	Aminotransferase
CSC50_RS05510	COG2409	Drug exporters of the RND superfamily
CSC50_RS05535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSC50_RS05540	COG3425	synthase
CSC50_RS05550	COG3942	CHAP domain
CSC50_RS05560	COG0583	DNA-binding transcription factor activity
CSC50_RS05575	COG0028	Belongs to the TPP enzyme family
CSC50_RS05595	COG0657	acetylesterase activity
CSC50_RS05600	COG0697	spore germination
CSC50_RS05615	COG1760	l-serine dehydratase
CSC50_RS05620	COG1760	l-serine dehydratase
CSC50_RS05640	COG3764	Sortase (surface protein transpeptidase)
CSC50_RS05650	COG1131	(ABC) transporter
CSC50_RS05655	COG0561	phosphatase activity
CSC50_RS05670	COG2514	catechol 2,3-dioxygenase activity
CSC50_RS05680	COG1846	Transcriptional regulator
CSC50_RS05685	COG0346	lactoylglutathione lyase activity
CSC50_RS05690	COG0400	carboxylic ester hydrolase activity
CSC50_RS05710	COG1131	(ABC) transporter
CSC50_RS05730	COG0586	Pfam SNARE associated Golgi protein
CSC50_RS05735	COG2271	Major facilitator Superfamily
CSC50_RS05745	COG4876	unkown
CSC50_RS05750	COG2357	RelA SpoT domain protein
CSC50_RS05755	COG0789	Transcriptional regulator
CSC50_RS05760	COG1802	Transcriptional regulator
CSC50_RS05765	COG1070	Carbohydrate kinase
CSC50_RS05800	COG1846	Transcriptional regulator
CSC50_RS05845	COG0494	nUDIX hydrolase
CSC50_RS05945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSC50_RS05950	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CSC50_RS05955	COG1028	Short-chain dehydrogenase reductase Sdr
CSC50_RS05960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CSC50_RS06015	COG0069	glutamate synthase activity
CSC50_RS06020	COG4808	Protein conserved in bacteria
CSC50_RS06040	COG1363	Peptidase, m42
CSC50_RS06045	COG4619	ABC transporter
CSC50_RS06050	COG0390	transport system, permease component
CSC50_RS06055	COG2814	Major facilitator Superfamily
CSC50_RS06060	COG2272	Belongs to the type-B carboxylesterase lipase family
CSC50_RS06065	COG0531	amino acid
CSC50_RS06075	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CSC50_RS06095	COG1174	glycine betaine transport
CSC50_RS06105	COG1174	glycine betaine transport
CSC50_RS06115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSC50_RS06140	COG0531	amino acid
CSC50_RS06155	COG1113	amino acid transport
CSC50_RS06175	COG2814	Major facilitator Superfamily
CSC50_RS06185	COG1929	Belongs to the glycerate kinase type-1 family
CSC50_RS06205	COG1132	(ABC) transporter
CSC50_RS06205	COG2375	cellular response to nickel ion
CSC50_RS06210	COG1132	(ABC) transporter
CSC50_RS06225	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CSC50_RS06230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSC50_RS06240	COG0156	8-amino-7-oxononanoate synthase activity
CSC50_RS06290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSC50_RS06310	COG2814	Major facilitator Superfamily
CSC50_RS06315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC50_RS06320	COG0765	amino acid transport
CSC50_RS06325	COG1126	abc transporter atp-binding protein
CSC50_RS06365	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSC50_RS06365	COG3443	Belongs to the bacterial solute-binding protein 9 family
CSC50_RS06380	COG2116	formate transmembrane transporter activity
CSC50_RS06385	COG0454	-acetyltransferase
CSC50_RS06395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSC50_RS06400	COG2146	nitrite reductase [NAD(P)H] activity
CSC50_RS06410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CSC50_RS06415	COG1140	nitrate reductase beta subunit
CSC50_RS06425	COG2181	nitrate reductase activity
CSC50_RS06445	COG0789	Transcriptional regulator
CSC50_RS06485	COG3871	stress protein (general stress protein 26)
CSC50_RS06500	COG1263	PTS System
CSC50_RS06500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC50_RS06515	COG1511	domain protein
CSC50_RS06545	COG0604	alcohol dehydrogenase
CSC50_RS06565	COG1620	l-lactate permease
CSC50_RS06630	COG2814	Major facilitator Superfamily
CSC50_RS06640	COG1566	PFAM secretion protein HlyD family protein
CSC50_RS06645	COG2814	Major facilitator Superfamily
CSC50_RS06655	COG0657	acetylesterase activity
CSC50_RS06670	COG0598	Magnesium transport protein CorA
CSC50_RS06680	COG0786	glutamate:sodium symporter activity
CSC50_RS06700	COG3152	Membrane
CSC50_RS06705	COG4152	abc transporter atp-binding protein
CSC50_RS06710	COG1668	transmembrane transport
CSC50_RS06730	COG2258	MOSC domain
CSC50_RS06755	COG0583	DNA-binding transcription factor activity
CSC50_RS06770	COG1473	amidohydrolase
CSC50_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
CSC50_RS06795	COG1737	Transcriptional regulator
CSC50_RS06800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC50_RS06800	COG1263	PTS System
CSC50_RS06810	COG0385	Bile acid
CSC50_RS06815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC50_RS06835	COG1113	amino acid transport
CSC50_RS06905	COG3942	CHAP domain
CSC50_RS06920	COG1757	Na H antiporter
CSC50_RS06930	COG3942	CHAP domain
CSC50_RS06995	COG4413	Urea transporter
CSC50_RS07000	COG1960	acyl-CoA dehydrogenase activity
CSC50_RS07015	COG1268	BioY protein
CSC50_RS07030	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSC50_RS07035	COG4149	molybdate abc transporter
CSC50_RS07040	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSC50_RS07045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSC50_RS07065	COG1763	Mo-molybdopterin cofactor biosynthetic process
CSC50_RS07135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSC50_RS07185	COG2252	PERMEase
CSC50_RS07300	COG0201	protein transport
CSC50_RS07415	COG0028	Belongs to the TPP enzyme family
CSC50_RS07420	COG3527	Alpha-acetolactate decarboxylase
CSC50_RS07440	COG5492	domain, Protein
CSC50_RS07450	COG0789	Transcriptional regulator
CSC50_RS07455	COG0656	L-ascorbic acid biosynthetic process
CSC50_RS07515	COG0582	viral genome integration into host DNA
CSC50_RS07775	COG5280	Phage tail tape measure protein TP901
CSC50_RS07775	COG3953	SLT domain
CSC50_RS07825	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC50_RS07825	COG1388	LysM domain
CSC50_RS07850	COG2130	NADP-dependent
CSC50_RS07860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC50_RS07885	COG2814	Major facilitator Superfamily
CSC50_RS07890	COG4264	IucA IucC family
CSC50_RS07895	COG3457	Alanine racemase
CSC50_RS07905	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CSC50_RS07910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC50_RS07915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC50_RS07920	COG3314	Sporulation integral membrane protein YlbJ
CSC50_RS07930	COG1988	membrane-bound metal-dependent
CSC50_RS07940	COG1272	protein, Hemolysin III
CSC50_RS07955	COG2814	Major facilitator Superfamily
CSC50_RS07960	COG0489	protein tyrosine kinase activity
CSC50_RS08020	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CSC50_RS08050	COG3711	transcriptional antiterminator
CSC50_RS08065	COG1119	ATPase activity
CSC50_RS08070	COG0561	phosphatase activity
CSC50_RS08105	COG0640	Transcriptional regulator
CSC50_RS08110	COG0702	epimerase
CSC50_RS08115	COG1482	cell wall glycoprotein biosynthetic process
CSC50_RS08135	COG0783	Belongs to the Dps family
CSC50_RS08140	COG0813	purine-nucleoside phosphorylase activity
CSC50_RS08190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC50_RS08230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSC50_RS08255	COG2890	protein-(glutamine-N5) methyltransferase activity
CSC50_RS08260	COG0009	L-threonylcarbamoyladenylate synthase
CSC50_RS08285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSC50_RS08360	COG0629	single-stranded DNA binding
CSC50_RS08415	COG1418	mRNA catabolic process
CSC50_RS08425	COG1937	Protein conserved in bacteria
CSC50_RS08440	COG0772	Belongs to the SEDS family
CSC50_RS08450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSC50_RS08470	COG0745	RESPONSE REGULATOR receiver
CSC50_RS08475	COG2205	protein histidine kinase activity
CSC50_RS08505	COG3428	Bacterial PH domain
CSC50_RS08540	COG2208	phosphoserine phosphatase activity
CSC50_RS08545	COG1366	Belongs to the anti-sigma-factor antagonist family
CSC50_RS08555	COG1191	sigma factor activity
CSC50_RS08560	COG2183	response to ionizing radiation
CSC50_RS08635	COG0028	Belongs to the TPP enzyme family
CSC50_RS08650	COG0802	atpase or kinase
CSC50_RS08655	COG1214	PFAM Peptidase M22, glycoprotease
CSC50_RS08660	COG0456	acetyltransferase
CSC50_RS08670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CSC50_RS08680	COG0488	(ABC) transporter
CSC50_RS08690	COG2391	methyltransferase activity
CSC50_RS08695	COG0425	Belongs to the sulfur carrier protein TusA family
CSC50_RS08700	COG0004	ammonium transporteR
CSC50_RS08705	COG1609	Transcriptional regulator
CSC50_RS08710	COG1621	beta-fructofuranosidase activity
CSC50_RS08715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC50_RS08785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSC50_RS09005	COG0740	serine-type endopeptidase activity
CSC50_RS09055	COG0739	heme binding
CSC50_RS09100	COG1388	LysM domain
CSC50_RS09100	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSC50_RS09120	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC50_RS09120	COG1388	LysM domain
CSC50_RS09180	COG1725	Transcriptional regulator
CSC50_RS09195	COG1131	(ABC) transporter
CSC50_RS09250	COG1012	belongs to the aldehyde dehydrogenase family
CSC50_RS09265	COG1335	isochorismatase
CSC50_RS09275	COG0471	metal ion transport
CSC50_RS09285	COG0077	Prephenate dehydratase
CSC50_RS09295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CSC50_RS09335	COG4496	protein, YerC YecD
CSC50_RS09355	COG4851	CamS sex pheromone cAM373 precursor
CSC50_RS09480	COG1295	ribonuclease BN
CSC50_RS09500	COG2309	aminopeptidase activity
CSC50_RS09505	COG1607	acyl-coa hydrolase
CSC50_RS09510	COG0535	radical SAM domain protein
CSC50_RS09540	COG1134	teichoic acid transport
CSC50_RS09540	COG1388	LysM domain
CSC50_RS09555	COG1988	membrane-bound metal-dependent
CSC50_RS09580	COG4129	membrane
CSC50_RS09590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSC50_RS09595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC50_RS09765	COG0765	amino acid transport
CSC50_RS09770	COG1126	abc transporter atp-binding protein
CSC50_RS09775	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSC50_RS09805	COG0564	pseudouridine synthase activity
CSC50_RS09810	COG2203	Gaf domain
CSC50_RS09810	COG4585	Histidine kinase
CSC50_RS09815	COG2197	response regulator
CSC50_RS09845	COG0420	3'-5' exonuclease activity
CSC50_RS09875	COG0537	adenosine 5'-monophosphoramidase activity
CSC50_RS09880	COG1131	(ABC) transporter
CSC50_RS09910	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CSC50_RS10175	COG2816	NAD+ diphosphatase activity
CSC50_RS10180	COG1506	peptidase
CSC50_RS10200	COG0656	L-ascorbic acid biosynthetic process
CSC50_RS10225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CSC50_RS10255	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSC50_RS10255	COG3266	domain, Protein
CSC50_RS10255	COG4193	domain, Protein
CSC50_RS10275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSC50_RS10275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSC50_RS10310	COG2267	carboxylic ester hydrolase activity
CSC50_RS10330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CSC50_RS10335	COG1242	4 iron, 4 sulfur cluster binding
CSC50_RS10340	COG2814	Major facilitator Superfamily
CSC50_RS10360	COG2081	HI0933 family
CSC50_RS10365	COG2244	polysaccharide biosynthetic process
CSC50_RS10370	COG1187	pseudouridine synthase activity
CSC50_RS10390	COG0510	thiamine kinase activity
CSC50_RS10400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC50_RS10410	COG1363	Peptidase, m42
CSC50_RS10415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSC50_RS10425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSC50_RS10430	COG1674	ftsk spoiiie
CSC50_RS10455	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CSC50_RS10455	COG1605	Chorismate mutase
CSC50_RS10475	COG0454	-acetyltransferase
CSC50_RS10480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSC50_RS10515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSC50_RS10520	COG0204	Acyl-transferase
CSC50_RS10525	COG1263	PTS System
CSC50_RS10525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC50_RS10540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC50_RS10545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSC50_RS10550	COG1764	response to oxidative stress
CSC50_RS10555	COG0584	glycerophosphoryl diester phosphodiesterase
CSC50_RS10575	COG1956	GAF domain-containing protein
CSC50_RS10590	COG1104	cysteine desulfurase activity
CSC50_RS10600	COG0730	response to heat
CSC50_RS10610	COG0827	DNA restriction-modification system
CSC50_RS10650	COG4109	DRTGG domain
CSC50_RS10655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CSC50_RS10665	COG0281	malic enzyme
CSC50_RS10690	COG1113	amino acid transport
CSC50_RS10695	COG0372	Belongs to the citrate synthase family
CSC50_RS10710	COG0745	RESPONSE REGULATOR receiver
CSC50_RS10715	COG5002	protein histidine kinase activity
CSC50_RS10725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC50_RS10725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC50_RS10755	COG1484	DNA-dependent DNA replication
CSC50_RS10770	COG0833	amino acid
CSC50_RS10795	COG4112	unkown
CSC50_RS10830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSC50_RS10865	COG2818	Glycosylase
CSC50_RS10875	COG0285	dihydrofolate synthase activity
CSC50_RS10885	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CSC50_RS10930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSC50_RS10975	COG2868	ribosomal protein
CSC50_RS11015	COG1862	Preprotein translocase
CSC50_RS11020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSC50_RS11020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSC50_RS11025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSC50_RS11025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CSC50_RS11070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSC50_RS11075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSC50_RS11080	COG1959	2 iron, 2 sulfur cluster binding
CSC50_RS11085	COG3237	CsbD-like
CSC50_RS11095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC50_RS11100	COG1104	cysteine desulfurase activity
CSC50_RS11120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSC50_RS11150	COG0826	peptidase U32
CSC50_RS11155	COG0826	peptidase U32
CSC50_RS11170	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CSC50_RS11175	COG1984	allophanate hydrolase subunit 2
CSC50_RS11180	COG0511	ligase activity, forming carbon-carbon bonds
CSC50_RS11185	COG0439	Biotin carboxylase
CSC50_RS11195	COG1914	H( )-stimulated, divalent metal cation uptake system
CSC50_RS11200	COG3177	Filamentation induced by cAMP protein fic
CSC50_RS11230	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CSC50_RS11235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CSC50_RS11245	COG1534	Rna-binding protein
CSC50_RS11255	COG1713	HD superfamily hydrolase involved in NAD metabolism
CSC50_RS11260	COG0799	negative regulation of ribosome biogenesis
CSC50_RS11265	COG2226	methyltransferase
CSC50_RS11270	COG2183	response to ionizing radiation
CSC50_RS11275	COG2131	deaminase
CSC50_RS11280	COG0658	competence protein
CSC50_RS11280	COG2333	competence protein COMEC
CSC50_RS11285	COG1466	dna polymerase III delta subunit
CSC50_RS11300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSC50_RS11330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSC50_RS11335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSC50_RS11345	COG1030	water channel activity
CSC50_RS11360	COG1702	phosphate starvation-inducible protein PhoH
CSC50_RS11375	COG0295	cytidine deaminase activity
CSC50_RS11395	COG0517	IMP dehydrogenase activity
CSC50_RS11415	COG2384	SAM-dependent methyltransferase
CSC50_RS11425	COG0513	Belongs to the DEAD box helicase family
CSC50_RS11435	COG1121	(ABC) transporter
CSC50_RS11440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC50_RS11455	COG0768	penicillin binding
CSC50_RS11465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSC50_RS11475	COG4483	Protein conserved in bacteria
CSC50_RS11480	COG1940	carbohydrate kinase activity
CSC50_RS11485	COG0011	TIGRFAM Protein of
CSC50_RS11490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC50_RS11495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSC50_RS11500	COG1459	type II secretion system
CSC50_RS11505	COG4537	Required for transformation and DNA binding
CSC50_RS11550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSC50_RS11555	COG0095	Lipoate-protein ligase
CSC50_RS11570	COG0006	proline dipeptidase activity
CSC50_RS11580	COG0511	ligase activity, forming carbon-carbon bonds
CSC50_RS11585	COG0439	Biotin carboxylase
CSC50_RS11590	COG1302	Protein conserved in bacteria
CSC50_RS11620	COG0497	DNA recombination
CSC50_RS11625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSC50_RS11630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSC50_RS11635	COG0022	dehydrogenase e1 component
CSC50_RS11640	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC50_RS11650	COG4129	membrane
CSC50_RS11660	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSC50_RS11685	COG1609	Transcriptional regulator
CSC50_RS11690	COG0366	Alpha amylase catalytic
CSC50_RS11700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSC50_RS11715	COG4221	oxidoreductase activity
CSC50_RS11725	COG0667	Aldo Keto reductase
CSC50_RS11730	COG0494	nUDIX hydrolase
CSC50_RS11735	COG0735	belongs to the Fur family
CSC50_RS11760	COG1187	pseudouridine synthase activity
CSC50_RS11765	COG0745	RESPONSE REGULATOR receiver
CSC50_RS11785	COG0582	viral genome integration into host DNA
CSC50_RS11805	COG2176	DNA-directed DNA polymerase activity
CSC50_RS12055	COG5280	Phage tail tape measure protein TP901
CSC50_RS12055	COG3953	SLT domain
CSC50_RS12105	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC50_RS12105	COG1388	LysM domain
CSC50_RS12150	COG1141	Ferredoxin
CSC50_RS12160	COG0514	ATP-dependent DNA helicase (RecQ)
CSC50_RS12175	COG0492	ferredoxin-NADP+ reductase activity
CSC50_RS12240	COG0142	geranyltranstransferase activity
CSC50_RS12280	COG4347	Protein of unknown function (DUF1405)
CSC50_RS12285	COG2738	Putative neutral zinc metallopeptidase
CSC50_RS12290	COG1694	Mazg nucleotide pyrophosphohydrolase
CSC50_RS12295	COG0438	transferase activity, transferring glycosyl groups
CSC50_RS12320	COG3935	DnaD domain protein
CSC50_RS12325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSC50_RS12335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSC50_RS12335	COG4499	WXG100 protein secretion system (Wss), protein YukC
CSC50_RS12375	COG0116	Belongs to the methyltransferase superfamily
CSC50_RS12390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CSC50_RS12395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC50_RS12410	COG0531	amino acid
CSC50_RS12435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CSC50_RS12510	COG0671	phosphoesterase, PA-phosphatase related
CSC50_RS12555	COG0714	Associated with various cellular activities
CSC50_RS12560	COG4548	von Willebrand factor, type A
CSC50_RS12635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSC50_RS12640	COG0527	aspartate kinase activity
CSC50_RS12650	COG0488	(ABC) transporter
CSC50_RS12670	COG0573	inorganic phosphate transmembrane transporter activity
CSC50_RS12675	COG0581	inorganic phosphate transmembrane transporter activity
CSC50_RS12685	COG0704	Plays a role in the regulation of phosphate uptake
CSC50_RS12730	COG0561	phosphatase activity
CSC50_RS12775	COG0512	Glutamine amidotransferase of anthranilate synthase
CSC50_RS12780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSC50_RS12785	COG1363	Peptidase, m42
CSC50_RS12795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSC50_RS12820	COG0628	permease
CSC50_RS12835	COG1115	amino acid carrier protein
CSC50_RS12875	COG0824	Thioesterase
CSC50_RS12890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC50_RS12910	COG4846	Membrane protein involved in cytochrome C biogenesis
CSC50_RS12945	COG2340	Cysteine-rich secretory protein family
CSC50_RS12975	COG0833	amino acid
CSC50_RS13000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSC50_RS13005	COG0460	homoserine dehydrogenase
CSC50_RS13010	COG0527	aspartate kinase activity
CSC50_RS13025	COG1525	nuclease
CSC50_RS13035	COG2197	response regulator
CSC50_RS13050	COG1131	(ABC) transporter
CSC50_RS13135	COG0789	Transcriptional regulator
CSC50_RS13140	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CSC50_RS13145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSC50_RS13155	COG1923	regulation of RNA biosynthetic process
CSC50_RS13180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CSC50_RS13185	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CSC50_RS13220	COG1013	pyruvate-flavodoxin oxidoreductase activity
CSC50_RS13225	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSC50_RS13225	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSC50_RS13230	COG1692	metallophosphoesterase
CSC50_RS13250	COG1546	Belongs to the CinA family
CSC50_RS13250	COG1058	Belongs to the CinA family
CSC50_RS13270	COG0300	oxidoreductase activity
CSC50_RS13275	COG0612	Peptidase, M16
CSC50_RS13280	COG0612	Peptidase, M16
CSC50_RS13285	COG2188	Transcriptional regulator
CSC50_RS13315	COG0196	riboflavin kinase activity
CSC50_RS13340	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CSC50_RS13345	COG0195	Participates in both transcription termination and antitermination
CSC50_RS13445	COG0758	DNA mediated transformation
CSC50_RS13450	COG0758	DNA mediated transformation
CSC50_RS13455	COG2348	transferase activity, transferring amino-acyl groups
CSC50_RS13510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSC50_RS13520	COG0552	protein localization to endoplasmic reticulum
CSC50_RS13525	COG1196	nuclear chromosome segregation
CSC50_RS13575	COG1302	Protein conserved in bacteria
CSC50_RS13590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSC50_RS13605	COG0631	protein serine/threonine phosphatase activity
CSC50_RS13615	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CSC50_RS13615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSC50_RS13630	COG2314	TM2 domain
CSC50_RS13640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSC50_RS13645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSC50_RS13660	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CSC50_RS13705	COG2233	PERMEase
CSC50_RS13715	COG0564	pseudouridine synthase activity
CSC50_RS13735	COG2514	catechol 2,3-dioxygenase activity
CSC50_RS13745	COG3599	regulation of cell shape
CSC50_RS13750	COG2302	S4 RNA-binding domain
CSC50_RS13755	COG0762	integral membrane protein
CSC50_RS13765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSC50_RS13780	COG0849	cell division
CSC50_RS13785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CSC50_RS13800	COG0768	penicillin binding
CSC50_RS13805	COG4839	cell division protein FtsL
CSC50_RS13830	COG1011	Hydrolase
CSC50_RS13865	COG1288	antiporter activity
CSC50_RS13995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSC50_RS14000	COG1053	succinate dehydrogenase
CSC50_RS14005	COG2009	succinate dehydrogenase
CSC50_RS14030	COG1796	DNA polymerase
CSC50_RS14030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSC50_RS14075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSC50_RS14090	COG4509	Sortase family
CSC50_RS14150	COG0742	ribosomal rna small subunit methyltransferase
CSC50_RS14170	COG3679	Belongs to the UPF0342 family
CSC50_RS14205	COG0772	Belongs to the SEDS family
CSC50_RS14215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSC50_RS14225	COG1217	gtp-binding protein TYPA
CSC50_RS14235	COG0483	inositol monophosphate 1-phosphatase activity
CSC50_RS14260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSC50_RS14265	COG1177	transmembrane transport
CSC50_RS14270	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC50_RS14335	COG0569	domain protein
CSC50_RS14340	COG1294	oxidase, subunit
CSC50_RS14345	COG1271	oxidase subunit
CSC50_RS14350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSC50_RS14370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CSC50_RS14395	COG4721	ABC-type cobalt transport system, permease component
CSC50_RS14400	COG4172	Belongs to the ABC transporter superfamily
CSC50_RS14405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CSC50_RS14445	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSC50_RS14460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSC50_RS14505	COG1316	TRANSCRIPTIONal
CSC50_RS14535	COG3594	Acyltransferase
CSC50_RS14540	COG0436	Aminotransferase
CSC50_RS14565	COG2267	carboxylic ester hydrolase activity
CSC50_RS14575	COG1169	isochorismate synthase
CSC50_RS14585	COG1575	Belongs to the MenA family. Type 1 subfamily
CSC50_RS14590	COG0456	acetyltransferase
CSC50_RS14595	COG2314	TM2 domain
CSC50_RS14605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CSC50_RS14660	COG4873	Protein conserved in bacteria
CSC50_RS14675	COG4903	ComK protein
CSC50_RS14690	COG0737	Belongs to the 5'-nucleotidase family
CSC50_RS14695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSC50_RS14705	COG0861	Integral membrane protein TerC family
CSC50_RS14745	COG1115	amino acid carrier protein
CSC50_RS14750	COG0628	permease
CSC50_RS14760	COG0475	glutathione-regulated potassium exporter activity
CSC50_RS14760	COG0569	domain protein
CSC50_RS14765	COG2239	Acts as a magnesium transporter
CSC50_RS14770	COG0564	pseudouridine synthase activity
CSC50_RS14780	COG2357	RelA SpoT domain protein
CSC50_RS14795	COG2346	COG2346, Truncated hemoglobins
CSC50_RS14805	COG1164	Oligoendopeptidase f
CSC50_RS14830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC50_RS14835	COG0601	transmembrane transport
CSC50_RS14840	COG4608	Belongs to the ABC transporter superfamily
CSC50_RS14845	COG0444	Belongs to the ABC transporter superfamily
CSC50_RS14850	COG0747	negative chemotaxis
CSC50_RS14855	COG4166	transmembrane transport
CSC50_RS14860	COG4608	Belongs to the ABC transporter superfamily
CSC50_RS14865	COG0444	Belongs to the ABC transporter superfamily
CSC50_RS14870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC50_RS14875	COG0601	transmembrane transport
CSC50_RS14905	COG1881	PFAM PEBP family protein
CSC50_RS14920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSC50_RS14945	COG0561	phosphatase activity
CSC50_RS14985	COG0398	Pfam SNARE associated Golgi protein
CSC50_RS15005	COG0584	glycerophosphoryl diester phosphodiesterase
CSC50_RS15020	COG1902	pentaerythritol trinitrate reductase activity
CSC50_RS15025	COG1098	S1 RNA binding domain
CSC50_RS15080	COG2050	protein possibly involved in aromatic compounds catabolism
CSC50_RS15085	COG2056	Na+-H+ antiporter family
CSC50_RS15090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSC50_RS15100	COG0316	Belongs to the HesB IscA family
CSC50_RS15110	COG1252	NADH dehydrogenase
CSC50_RS15115	COG4837	Protein of unknown function (DUF1462)
CSC50_RS15120	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CSC50_RS15125	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CSC50_RS15135	COG1696	Membrane protein involved in D-alanine export
CSC50_RS15165	COG2445	Protein of unknown function DUF86
CSC50_RS15185	COG4470	Protein conserved in bacteria
CSC50_RS15200	COG0730	response to heat
CSC50_RS15205	COG1801	Protein of unknown function DUF72
CSC50_RS15220	COG1253	flavin adenine dinucleotide binding
CSC50_RS15260	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC50_RS15260	COG1388	LysM domain
CSC50_RS15490	COG1484	DNA-dependent DNA replication