locus-tag	class	description
CSC58_RS00005	COG2258	MOSC domain
CSC58_RS00030	COG0583	DNA-binding transcription factor activity
CSC58_RS00045	COG1473	amidohydrolase
CSC58_RS00050	COG1028	Short-chain dehydrogenase reductase Sdr
CSC58_RS00070	COG1737	Transcriptional regulator
CSC58_RS00075	COG1263	PTS System
CSC58_RS00075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC58_RS00085	COG0385	Bile acid
CSC58_RS00090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC58_RS00110	COG1113	amino acid transport
CSC58_RS00185	COG3942	CHAP domain
CSC58_RS00200	COG1757	Na H antiporter
CSC58_RS00275	COG4413	Urea transporter
CSC58_RS00280	COG1960	acyl-CoA dehydrogenase activity
CSC58_RS00295	COG1268	BioY protein
CSC58_RS00310	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSC58_RS00315	COG4149	molybdate abc transporter
CSC58_RS00320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSC58_RS00325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSC58_RS00345	COG1763	Mo-molybdopterin cofactor biosynthetic process
CSC58_RS00415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSC58_RS00465	COG2252	PERMEase
CSC58_RS00580	COG0201	protein transport
CSC58_RS00670	COG0028	Belongs to the TPP enzyme family
CSC58_RS00675	COG3527	Alpha-acetolactate decarboxylase
CSC58_RS00685	COG5492	domain, Protein
CSC58_RS00695	COG0789	Transcriptional regulator
CSC58_RS00700	COG0656	L-ascorbic acid biosynthetic process
CSC58_RS00775	COG2130	NADP-dependent
CSC58_RS00785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC58_RS00810	COG2814	Major facilitator Superfamily
CSC58_RS00815	COG4264	IucA IucC family
CSC58_RS00820	COG3457	Alanine racemase
CSC58_RS00830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CSC58_RS00835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC58_RS00840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC58_RS00845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC58_RS00850	COG3314	Sporulation integral membrane protein YlbJ
CSC58_RS00860	COG1988	membrane-bound metal-dependent
CSC58_RS00870	COG1272	protein, Hemolysin III
CSC58_RS00885	COG2814	Major facilitator Superfamily
CSC58_RS00890	COG0489	protein tyrosine kinase activity
CSC58_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CSC58_RS00980	COG3711	transcriptional antiterminator
CSC58_RS00995	COG1119	ATPase activity
CSC58_RS01000	COG0561	phosphatase activity
CSC58_RS01035	COG0640	Transcriptional regulator
CSC58_RS01040	COG0702	epimerase
CSC58_RS01045	COG1482	cell wall glycoprotein biosynthetic process
CSC58_RS01065	COG0783	Belongs to the Dps family
CSC58_RS01070	COG0813	purine-nucleoside phosphorylase activity
CSC58_RS01120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC58_RS01170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSC58_RS01195	COG2890	protein-(glutamine-N5) methyltransferase activity
CSC58_RS01200	COG0009	L-threonylcarbamoyladenylate synthase
CSC58_RS01225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSC58_RS01300	COG0629	single-stranded DNA binding
CSC58_RS01340	COG1418	mRNA catabolic process
CSC58_RS01350	COG1937	Protein conserved in bacteria
CSC58_RS01365	COG0772	Belongs to the SEDS family
CSC58_RS01375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSC58_RS01385	COG0745	RESPONSE REGULATOR receiver
CSC58_RS01390	COG2205	protein histidine kinase activity
CSC58_RS01420	COG3428	Bacterial PH domain
CSC58_RS01455	COG2208	phosphoserine phosphatase activity
CSC58_RS01460	COG1366	Belongs to the anti-sigma-factor antagonist family
CSC58_RS01470	COG1191	sigma factor activity
CSC58_RS01475	COG2183	response to ionizing radiation
CSC58_RS01560	COG0028	Belongs to the TPP enzyme family
CSC58_RS01575	COG0802	atpase or kinase
CSC58_RS01580	COG1214	PFAM Peptidase M22, glycoprotease
CSC58_RS01585	COG0456	acetyltransferase
CSC58_RS01595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CSC58_RS01605	COG0488	(ABC) transporter
CSC58_RS01615	COG2391	methyltransferase activity
CSC58_RS01620	COG0425	Belongs to the sulfur carrier protein TusA family
CSC58_RS01625	COG0004	ammonium transporteR
CSC58_RS01630	COG1609	Transcriptional regulator
CSC58_RS01635	COG1621	beta-fructofuranosidase activity
CSC58_RS01640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC58_RS01705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSC58_RS01710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSC58_RS01715	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CSC58_RS01765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSC58_RS01935	COG0740	serine-type endopeptidase activity
CSC58_RS01985	COG0739	heme binding
CSC58_RS02030	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSC58_RS02030	COG1388	LysM domain
CSC58_RS02045	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC58_RS02045	COG1388	LysM domain
CSC58_RS02105	COG1725	Transcriptional regulator
CSC58_RS02120	COG1131	(ABC) transporter
CSC58_RS02170	COG4974	Belongs to the 'phage' integrase family
CSC58_RS02200	COG3682	Transcriptional regulator
CSC58_RS02210	COG1012	belongs to the aldehyde dehydrogenase family
CSC58_RS02225	COG1335	isochorismatase
CSC58_RS02245	COG0077	Prephenate dehydratase
CSC58_RS02255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CSC58_RS02290	COG4496	protein, YerC YecD
CSC58_RS02300	COG0210	DNA helicase
CSC58_RS02310	COG4851	CamS sex pheromone cAM373 precursor
CSC58_RS02435	COG2197	response regulator
CSC58_RS02440	COG1295	ribonuclease BN
CSC58_RS02460	COG2309	aminopeptidase activity
CSC58_RS02465	COG1607	acyl-coa hydrolase
CSC58_RS02470	COG0535	radical SAM domain protein
CSC58_RS02500	COG1134	teichoic acid transport
CSC58_RS02500	COG1388	LysM domain
CSC58_RS02515	COG1988	membrane-bound metal-dependent
CSC58_RS02540	COG4129	membrane
CSC58_RS02550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSC58_RS02555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC58_RS02720	COG0765	amino acid transport
CSC58_RS02725	COG1126	abc transporter atp-binding protein
CSC58_RS02730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSC58_RS02770	COG0564	pseudouridine synthase activity
CSC58_RS02775	COG2203	Gaf domain
CSC58_RS02775	COG4585	Histidine kinase
CSC58_RS02780	COG2197	response regulator
CSC58_RS02810	COG0420	3'-5' exonuclease activity
CSC58_RS02845	COG0537	adenosine 5'-monophosphoramidase activity
CSC58_RS02850	COG1131	(ABC) transporter
CSC58_RS02880	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CSC58_RS03190	COG1506	peptidase
CSC58_RS03210	COG0656	L-ascorbic acid biosynthetic process
CSC58_RS03235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CSC58_RS03265	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSC58_RS03265	COG4193	domain, Protein
CSC58_RS03265	COG3266	domain, Protein
CSC58_RS03285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSC58_RS03285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSC58_RS03320	COG2267	carboxylic ester hydrolase activity
CSC58_RS03335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CSC58_RS03340	COG1242	4 iron, 4 sulfur cluster binding
CSC58_RS03345	COG2814	Major facilitator Superfamily
CSC58_RS03365	COG2081	HI0933 family
CSC58_RS03370	COG2244	polysaccharide biosynthetic process
CSC58_RS03375	COG1187	pseudouridine synthase activity
CSC58_RS03395	COG0510	thiamine kinase activity
CSC58_RS03405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC58_RS03415	COG1363	Peptidase, m42
CSC58_RS03420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSC58_RS03430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSC58_RS03435	COG1674	ftsk spoiiie
CSC58_RS03460	COG1605	Chorismate mutase
CSC58_RS03460	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CSC58_RS03480	COG0454	-acetyltransferase
CSC58_RS03485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSC58_RS03490	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CSC58_RS03520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSC58_RS03525	COG0204	Acyl-transferase
CSC58_RS03530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC58_RS03530	COG1263	PTS System
CSC58_RS03545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC58_RS03550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSC58_RS03555	COG1764	response to oxidative stress
CSC58_RS03560	COG0584	glycerophosphoryl diester phosphodiesterase
CSC58_RS03580	COG1956	GAF domain-containing protein
CSC58_RS03585	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CSC58_RS03595	COG1104	cysteine desulfurase activity
CSC58_RS03615	COG0827	DNA restriction-modification system
CSC58_RS03655	COG4109	DRTGG domain
CSC58_RS03665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CSC58_RS03675	COG0281	malic enzyme
CSC58_RS03700	COG1113	amino acid transport
CSC58_RS03705	COG0372	Belongs to the citrate synthase family
CSC58_RS03720	COG0745	RESPONSE REGULATOR receiver
CSC58_RS03725	COG5002	protein histidine kinase activity
CSC58_RS03735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC58_RS03735	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC58_RS03765	COG1484	DNA-dependent DNA replication
CSC58_RS03780	COG0833	amino acid
CSC58_RS03805	COG4112	unkown
CSC58_RS03840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSC58_RS03875	COG2818	Glycosylase
CSC58_RS03885	COG0285	dihydrofolate synthase activity
CSC58_RS03895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CSC58_RS03940	COG2868	ribosomal protein
CSC58_RS03980	COG1862	Preprotein translocase
CSC58_RS03985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSC58_RS03985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSC58_RS03990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSC58_RS03990	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CSC58_RS04035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSC58_RS04040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSC58_RS04045	COG1959	2 iron, 2 sulfur cluster binding
CSC58_RS04050	COG3237	CsbD-like
CSC58_RS04060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC58_RS04065	COG1104	cysteine desulfurase activity
CSC58_RS04085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSC58_RS04115	COG0826	peptidase U32
CSC58_RS04120	COG0826	peptidase U32
CSC58_RS04135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CSC58_RS04140	COG1984	allophanate hydrolase subunit 2
CSC58_RS04145	COG0511	ligase activity, forming carbon-carbon bonds
CSC58_RS04150	COG0439	Biotin carboxylase
CSC58_RS04160	COG1914	H( )-stimulated, divalent metal cation uptake system
CSC58_RS04185	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CSC58_RS04190	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CSC58_RS04200	COG1534	Rna-binding protein
CSC58_RS04210	COG1713	HD superfamily hydrolase involved in NAD metabolism
CSC58_RS04215	COG0799	negative regulation of ribosome biogenesis
CSC58_RS04220	COG2226	methyltransferase
CSC58_RS04230	COG2131	deaminase
CSC58_RS04235	COG2333	competence protein COMEC
CSC58_RS04235	COG0658	competence protein
CSC58_RS04240	COG1466	dna polymerase III delta subunit
CSC58_RS04260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSC58_RS04290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSC58_RS04295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSC58_RS04305	COG1030	water channel activity
CSC58_RS04320	COG1702	phosphate starvation-inducible protein PhoH
CSC58_RS04335	COG0295	cytidine deaminase activity
CSC58_RS04355	COG0517	IMP dehydrogenase activity
CSC58_RS04375	COG2384	SAM-dependent methyltransferase
CSC58_RS04385	COG0513	Belongs to the DEAD box helicase family
CSC58_RS04395	COG1121	(ABC) transporter
CSC58_RS04400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC58_RS04415	COG0768	penicillin binding
CSC58_RS04425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSC58_RS04435	COG4483	Protein conserved in bacteria
CSC58_RS04440	COG1940	carbohydrate kinase activity
CSC58_RS04445	COG0011	TIGRFAM Protein of
CSC58_RS04450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC58_RS04455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSC58_RS04460	COG1459	type II secretion system
CSC58_RS04465	COG4537	Required for transformation and DNA binding
CSC58_RS04510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSC58_RS04515	COG0095	Lipoate-protein ligase
CSC58_RS04530	COG0006	proline dipeptidase activity
CSC58_RS04540	COG0511	ligase activity, forming carbon-carbon bonds
CSC58_RS04545	COG0439	Biotin carboxylase
CSC58_RS04550	COG1302	Protein conserved in bacteria
CSC58_RS04580	COG0497	DNA recombination
CSC58_RS04585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSC58_RS04590	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSC58_RS04595	COG0022	dehydrogenase e1 component
CSC58_RS04600	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC58_RS04610	COG4129	membrane
CSC58_RS04620	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSC58_RS04640	COG1609	Transcriptional regulator
CSC58_RS04645	COG0366	Alpha amylase catalytic
CSC58_RS04655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSC58_RS04670	COG4221	oxidoreductase activity
CSC58_RS04680	COG0667	Aldo Keto reductase
CSC58_RS04685	COG0494	nUDIX hydrolase
CSC58_RS04690	COG0735	belongs to the Fur family
CSC58_RS04715	COG1187	pseudouridine synthase activity
CSC58_RS04720	COG0745	RESPONSE REGULATOR receiver
CSC58_RS04725	COG5002	protein histidine kinase activity
CSC58_RS04740	COG0582	viral genome integration into host DNA
CSC58_RS05005	COG5280	Phage tail tape measure protein TP901
CSC58_RS05005	COG3953	SLT domain
CSC58_RS05055	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC58_RS05055	COG1388	LysM domain
CSC58_RS05095	COG1141	Ferredoxin
CSC58_RS05105	COG0514	ATP-dependent DNA helicase (RecQ)
CSC58_RS05120	COG0492	ferredoxin-NADP+ reductase activity
CSC58_RS05185	COG0142	geranyltranstransferase activity
CSC58_RS05225	COG4347	Protein of unknown function (DUF1405)
CSC58_RS05230	COG2738	Putative neutral zinc metallopeptidase
CSC58_RS05235	COG1694	Mazg nucleotide pyrophosphohydrolase
CSC58_RS05240	COG0438	transferase activity, transferring glycosyl groups
CSC58_RS05265	COG3935	DnaD domain protein
CSC58_RS05270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSC58_RS05280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSC58_RS05280	COG4499	WXG100 protein secretion system (Wss), protein YukC
CSC58_RS05315	COG0116	Belongs to the methyltransferase superfamily
CSC58_RS05330	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CSC58_RS05335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC58_RS05350	COG0531	amino acid
CSC58_RS05375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CSC58_RS05450	COG0671	phosphoesterase, PA-phosphatase related
CSC58_RS05495	COG0714	Associated with various cellular activities
CSC58_RS05500	COG4548	von Willebrand factor, type A
CSC58_RS05590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSC58_RS05595	COG0527	aspartate kinase activity
CSC58_RS05600	COG0488	(ABC) transporter
CSC58_RS05615	COG0573	inorganic phosphate transmembrane transporter activity
CSC58_RS05620	COG0581	inorganic phosphate transmembrane transporter activity
CSC58_RS05630	COG0704	Plays a role in the regulation of phosphate uptake
CSC58_RS05675	COG0561	phosphatase activity
CSC58_RS05715	COG0512	Glutamine amidotransferase of anthranilate synthase
CSC58_RS05720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSC58_RS05725	COG1363	Peptidase, m42
CSC58_RS05735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSC58_RS05760	COG0628	permease
CSC58_RS05775	COG1115	amino acid carrier protein
CSC58_RS05785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSC58_RS05815	COG0824	Thioesterase
CSC58_RS05830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC58_RS05850	COG4846	Membrane protein involved in cytochrome C biogenesis
CSC58_RS05885	COG2340	Cysteine-rich secretory protein family
CSC58_RS05915	COG0833	amino acid
CSC58_RS05940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSC58_RS05945	COG0460	homoserine dehydrogenase
CSC58_RS05950	COG0527	aspartate kinase activity
CSC58_RS05965	COG1525	nuclease
CSC58_RS05975	COG2197	response regulator
CSC58_RS05990	COG1131	(ABC) transporter
CSC58_RS06095	COG0789	Transcriptional regulator
CSC58_RS06100	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CSC58_RS06105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSC58_RS06115	COG1923	regulation of RNA biosynthetic process
CSC58_RS06140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CSC58_RS06145	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CSC58_RS06180	COG1013	pyruvate-flavodoxin oxidoreductase activity
CSC58_RS06185	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSC58_RS06185	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSC58_RS06190	COG1692	metallophosphoesterase
CSC58_RS06210	COG1546	Belongs to the CinA family
CSC58_RS06210	COG1058	Belongs to the CinA family
CSC58_RS06230	COG0300	oxidoreductase activity
CSC58_RS06235	COG0612	Peptidase, M16
CSC58_RS06240	COG0612	Peptidase, M16
CSC58_RS06245	COG2188	Transcriptional regulator
CSC58_RS06275	COG0196	riboflavin kinase activity
CSC58_RS06300	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CSC58_RS06305	COG0195	Participates in both transcription termination and antitermination
CSC58_RS06405	COG0758	DNA mediated transformation
CSC58_RS06410	COG2348	transferase activity, transferring amino-acyl groups
CSC58_RS06465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSC58_RS06475	COG0552	protein localization to endoplasmic reticulum
CSC58_RS06480	COG1196	nuclear chromosome segregation
CSC58_RS06530	COG1302	Protein conserved in bacteria
CSC58_RS06545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSC58_RS06560	COG0631	protein serine/threonine phosphatase activity
CSC58_RS06570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSC58_RS06570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CSC58_RS06595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSC58_RS06600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSC58_RS06615	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CSC58_RS06660	COG2233	PERMEase
CSC58_RS06670	COG0564	pseudouridine synthase activity
CSC58_RS06690	COG2514	catechol 2,3-dioxygenase activity
CSC58_RS06700	COG3599	regulation of cell shape
CSC58_RS06705	COG2302	S4 RNA-binding domain
CSC58_RS06710	COG0762	integral membrane protein
CSC58_RS06720	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSC58_RS06735	COG0849	cell division
CSC58_RS06740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CSC58_RS06755	COG0768	penicillin binding
CSC58_RS06760	COG4839	cell division protein FtsL
CSC58_RS06785	COG1011	Hydrolase
CSC58_RS06825	COG1288	antiporter activity
CSC58_RS06940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSC58_RS06945	COG1053	succinate dehydrogenase
CSC58_RS06950	COG2009	succinate dehydrogenase
CSC58_RS06975	COG1796	DNA polymerase
CSC58_RS06975	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSC58_RS07010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSC58_RS07025	COG4509	Sortase family
CSC58_RS07085	COG0742	ribosomal rna small subunit methyltransferase
CSC58_RS07105	COG3679	Belongs to the UPF0342 family
CSC58_RS07140	COG0772	Belongs to the SEDS family
CSC58_RS07150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSC58_RS07160	COG1217	gtp-binding protein TYPA
CSC58_RS07170	COG0483	inositol monophosphate 1-phosphatase activity
CSC58_RS07195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSC58_RS07200	COG1177	transmembrane transport
CSC58_RS07205	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC58_RS07270	COG0569	domain protein
CSC58_RS07275	COG1294	oxidase, subunit
CSC58_RS07280	COG1271	oxidase subunit
CSC58_RS07305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CSC58_RS07330	COG4721	ABC-type cobalt transport system, permease component
CSC58_RS07335	COG4172	Belongs to the ABC transporter superfamily
CSC58_RS07340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CSC58_RS07380	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSC58_RS07395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSC58_RS07440	COG1316	TRANSCRIPTIONal
CSC58_RS07470	COG3594	Acyltransferase
CSC58_RS07475	COG0436	Aminotransferase
CSC58_RS07500	COG2267	carboxylic ester hydrolase activity
CSC58_RS07510	COG1169	isochorismate synthase
CSC58_RS07520	COG1575	Belongs to the MenA family. Type 1 subfamily
CSC58_RS07525	COG0456	acetyltransferase
CSC58_RS07530	COG2314	TM2 domain
CSC58_RS07540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CSC58_RS07595	COG4873	Protein conserved in bacteria
CSC58_RS07610	COG4903	ComK protein
CSC58_RS07625	COG0737	Belongs to the 5'-nucleotidase family
CSC58_RS07630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSC58_RS07640	COG0861	Integral membrane protein TerC family
CSC58_RS07690	COG1115	amino acid carrier protein
CSC58_RS07695	COG0628	permease
CSC58_RS07705	COG0569	domain protein
CSC58_RS07705	COG0475	glutathione-regulated potassium exporter activity
CSC58_RS07710	COG2239	Acts as a magnesium transporter
CSC58_RS07715	COG0564	pseudouridine synthase activity
CSC58_RS07725	COG2357	RelA SpoT domain protein
CSC58_RS07740	COG2346	COG2346, Truncated hemoglobins
CSC58_RS07750	COG1164	Oligoendopeptidase f
CSC58_RS07775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC58_RS07780	COG0601	transmembrane transport
CSC58_RS07785	COG4608	Belongs to the ABC transporter superfamily
CSC58_RS07790	COG0444	Belongs to the ABC transporter superfamily
CSC58_RS07795	COG0747	negative chemotaxis
CSC58_RS07800	COG4166	transmembrane transport
CSC58_RS07805	COG4608	Belongs to the ABC transporter superfamily
CSC58_RS07810	COG0444	Belongs to the ABC transporter superfamily
CSC58_RS07815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC58_RS07820	COG0601	transmembrane transport
CSC58_RS07850	COG1881	PFAM PEBP family protein
CSC58_RS07890	COG0561	phosphatase activity
CSC58_RS07940	COG0398	Pfam SNARE associated Golgi protein
CSC58_RS07960	COG0584	glycerophosphoryl diester phosphodiesterase
CSC58_RS07975	COG1902	pentaerythritol trinitrate reductase activity
CSC58_RS07980	COG1098	S1 RNA binding domain
CSC58_RS08035	COG2050	protein possibly involved in aromatic compounds catabolism
CSC58_RS08040	COG2056	Na+-H+ antiporter family
CSC58_RS08045	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSC58_RS08055	COG0316	Belongs to the HesB IscA family
CSC58_RS08065	COG1252	NADH dehydrogenase
CSC58_RS08070	COG4837	Protein of unknown function (DUF1462)
CSC58_RS08075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CSC58_RS08080	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CSC58_RS08090	COG1696	Membrane protein involved in D-alanine export
CSC58_RS08120	COG2445	Protein of unknown function DUF86
CSC58_RS08130	COG4470	Protein conserved in bacteria
CSC58_RS08145	COG0730	response to heat
CSC58_RS08150	COG1801	Protein of unknown function DUF72
CSC58_RS08160	COG1253	flavin adenine dinucleotide binding
CSC58_RS08185	COG0822	iron-sulfur transferase activity
CSC58_RS08195	COG0719	Fe-S assembly protein
CSC58_RS08200	COG0396	ATPase activity
CSC58_RS08215	COG1464	Belongs to the NlpA lipoprotein family
CSC58_RS08220	COG2011	ABC-type metal ion transport system permease component
CSC58_RS08235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CSC58_RS08240	COG3878	Protein conserved in bacteria
CSC58_RS08255	COG1393	Belongs to the ArsC family
CSC58_RS08260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSC58_RS08285	COG1279	arginine transmembrane transporter activity
CSC58_RS08290	COG0406	alpha-ribazole phosphatase activity
CSC58_RS08330	COG1278	Cold shock
CSC58_RS08390	COG0557	exoribonuclease II activity
CSC58_RS08395	COG1647	Serine aminopeptidase, S33
CSC58_RS08400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSC58_RS08465	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CSC58_RS08530	COG1388	LysM domain
CSC58_RS08530	COG3942	CHAP domain
CSC58_RS08560	COG1040	competence protein
CSC58_RS08565	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CSC58_RS08575	COG1739	Uncharacterized protein family UPF0029
CSC58_RS08580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSC58_RS08635	COG4607	ABC-type enterochelin transport system periplasmic component
CSC58_RS08640	COG4604	ABC transporter, ATP-binding protein
CSC58_RS08645	COG4605	iron ion homeostasis
CSC58_RS08650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC58_RS08660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC58_RS08665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC58_RS08695	COG3104	oligopeptide transport
CSC58_RS08725	COG1174	glycine betaine transport
CSC58_RS08730	COG0517	IMP dehydrogenase activity
CSC58_RS08730	COG1125	glycine betaine transport
CSC58_RS08735	COG0514	ATP-dependent DNA helicase (RecQ)
CSC58_RS08740	COG0488	(ABC) transporter
CSC58_RS08770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSC58_RS08775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSC58_RS08775	COG0512	Glutamine amidotransferase of anthranilate synthase
CSC58_RS08785	COG0720	synthase
CSC58_RS08820	COG0463	Glycosyl transferase, family 2
CSC58_RS08825	COG0656	L-ascorbic acid biosynthetic process
CSC58_RS08830	COG1253	flavin adenine dinucleotide binding
CSC58_RS08835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CSC58_RS08840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC58_RS08840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC58_RS08840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC58_RS08845	COG1105	Belongs to the carbohydrate kinase PfkB family
CSC58_RS08850	COG1349	DNA-binding transcription factor activity
CSC58_RS08855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSC58_RS08885	COG0415	Belongs to the DNA photolyase family
CSC58_RS08890	COG0471	metal ion transport
CSC58_RS08900	COG4989	oxidoreductase activity
CSC58_RS08905	COG0523	cobalamin synthesis protein
CSC58_RS08915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CSC58_RS08920	COG4988	ABC transporter
CSC58_RS08940	COG1611	Belongs to the LOG family
CSC58_RS08970	COG2839	Protein conserved in bacteria
CSC58_RS08975	COG2814	Major facilitator Superfamily
CSC58_RS08985	COG0583	DNA-binding transcription factor activity
CSC58_RS09015	COG4977	sequence-specific DNA binding
CSC58_RS09015	COG1917	Cupin 2, conserved barrel domain protein
CSC58_RS09025	COG3942	CHAP domain
CSC58_RS09025	COG1388	LysM domain
CSC58_RS09030	COG0306	phosphate transporter
CSC58_RS09035	COG1392	Phosphate transport regulator
CSC58_RS09040	COG0577	efflux transmembrane transporter activity
CSC58_RS09045	COG1136	(ABC) transporter
CSC58_RS09060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC58_RS09085	COG3949	Membrane
CSC58_RS09095	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CSC58_RS09105	COG2376	Dihydroxyacetone kinase
CSC58_RS09110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC58_RS09115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC58_RS09120	COG1120	ATPase activity
CSC58_RS09125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSC58_RS09145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC58_RS09150	COG1132	(ABC) transporter
CSC58_RS09155	COG1686	Belongs to the peptidase S11 family
CSC58_RS09160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CSC58_RS09170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CSC58_RS09175	COG1682	transport, permease protein
CSC58_RS09185	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CSC58_RS09195	COG1321	iron dependent repressor
CSC58_RS09200	COG1121	(ABC) transporter
CSC58_RS09205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC58_RS09210	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSC58_RS09255	COG4974	Belongs to the 'phage' integrase family
CSC58_RS09305	COG4139	cobalamin transport
CSC58_RS09310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSC58_RS09345	COG1078	dGTPase activity
CSC58_RS09355	COG0655	NAD(P)H dehydrogenase (quinone) activity
CSC58_RS09365	COG0667	Aldo Keto reductase
CSC58_RS09400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSC58_RS09420	COG0083	homoserine kinase activity
CSC58_RS09435	COG0095	Lipoate-protein ligase
CSC58_RS09550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CSC58_RS09595	COG0561	phosphatase activity
CSC58_RS09605	COG1428	Deoxynucleoside kinase
CSC58_RS09610	COG1428	Deoxynucleoside kinase
CSC58_RS09615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSC58_RS09650	COG1473	amidohydrolase
CSC58_RS09690	COG2813	Specifically methylates the guanine in position
CSC58_RS09750	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CSC58_RS09775	COG4956	integral membrane protein (PIN domain superfamily)
CSC58_RS09780	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSC58_RS09795	COG3880	PFAM UvrB UvrC protein
CSC58_RS09805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC58_RS09820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC58_RS09915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSC58_RS09940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSC58_RS09955	COG1098	S1 RNA binding domain
CSC58_RS09965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSC58_RS09970	COG3956	TIGRFAM MazG family protein
CSC58_RS09975	COG2244	polysaccharide biosynthetic process
CSC58_RS10020	COG0251	oxidation-reduction process
CSC58_RS10025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CSC58_RS10035	COG4466	Protein conserved in bacteria
CSC58_RS10045	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CSC58_RS10050	COG0084	hydrolase, TatD family'
CSC58_RS10060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSC58_RS10070	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CSC58_RS10080	COG1774	PSP1 C-terminal conserved region
CSC58_RS10085	COG0470	DNA polymerase III
CSC58_RS10090	COG3870	Protein conserved in bacteria
CSC58_RS10100	COG1982	Orn Lys Arg decarboxylase major
CSC58_RS10140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSC58_RS10160	COG2188	Transcriptional regulator
CSC58_RS10165	COG0366	Alpha amylase catalytic
CSC58_RS10170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC58_RS10170	COG1263	PTS System
CSC58_RS10180	COG0493	'glutamate synthase
CSC58_RS10185	COG0069	glutamate synthase activity
CSC58_RS10185	COG0067	glutamate synthase
CSC58_RS10185	COG0070	glutamate synthase
CSC58_RS10190	COG0583	DNA-binding transcription factor activity
CSC58_RS10225	COG1464	Belongs to the NlpA lipoprotein family
CSC58_RS10230	COG2011	ABC-type metal ion transport system permease component
CSC58_RS10240	COG0626	cystathionine gamma-synthase activity
CSC58_RS10245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSC58_RS10250	COG0733	neurotransmitter:sodium symporter activity
CSC58_RS10260	COG1647	Serine aminopeptidase, S33
CSC58_RS10275	COG5609	conserved protein (DUF2294)
CSC58_RS10285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSC58_RS10310	COG0523	cobalamin synthesis protein
CSC58_RS10460	COG3759	membrane
CSC58_RS10560	COG2856	Zn peptidase
CSC58_RS10565	COG5484	DNA packaging
CSC58_RS10565	COG3728	DNA packaging
CSC58_RS10635	COG0582	viral genome integration into host DNA
CSC58_RS10650	COG2233	PERMEase
CSC58_RS10685	COG1823	symporter activity
CSC58_RS10790	COG0012	GTP binding
CSC58_RS10795	COG4481	Protein conserved in bacteria
CSC58_RS10800	COG0668	transmembrane transport
CSC58_RS10805	COG1475	DNA binding
CSC58_RS10815	COG0626	cystathionine gamma-synthase activity
CSC58_RS10820	COG0626	cystathionine gamma-synthase activity
CSC58_RS10825	COG0646	methionine synthase
CSC58_RS10825	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSC58_RS10855	COG1131	(ABC) transporter
CSC58_RS10865	COG1476	TRANSCRIPTIONal
CSC58_RS10875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSC58_RS10880	COG0805	protein transport
CSC58_RS10885	COG0672	)-iron permease
CSC58_RS10895	COG2822	iron ion transport
CSC58_RS10900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC58_RS10915	COG0431	NADPH-dependent FMN reductase
CSC58_RS10920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC58_RS10925	COG0346	lactoylglutathione lyase activity
CSC58_RS10930	COG2271	Major facilitator Superfamily
CSC58_RS10955	COG3711	transcriptional antiterminator
CSC58_RS10960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC58_RS10970	COG3037	sugar-specific permease SgaT UlaA
CSC58_RS11000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC58_RS11025	COG3314	Sporulation integral membrane protein YlbJ
CSC58_RS11050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSC58_RS11055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC58_RS11085	COG0577	efflux transmembrane transporter activity
CSC58_RS11095	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CSC58_RS11105	COG1114	Component of the transport system for branched-chain amino acids
CSC58_RS11280	COG1388	LysM domain
CSC58_RS11280	COG3942	CHAP domain
CSC58_RS11315	COG1131	(ABC) transporter
CSC58_RS11370	COG2226	methyltransferase
CSC58_RS11375	COG2723	6-phospho-beta-galactosidase activity
CSC58_RS11380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC58_RS11380	COG2190	(PTS) system
CSC58_RS11380	COG1263	PTS System
CSC58_RS11390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC58_RS11425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CSC58_RS11430	COG1063	alcohol dehydrogenase
CSC58_RS11440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CSC58_RS11450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CSC58_RS11455	COG1063	alcohol dehydrogenase
CSC58_RS11465	COG1063	alcohol dehydrogenase
CSC58_RS11475	COG1063	alcohol dehydrogenase
CSC58_RS11480	COG3775	system Galactitol-specific IIC component
CSC58_RS11485	COG3414	Phosphotransferase system galactitol-specific IIB component
CSC58_RS11505	COG1957	nucleoside hydrolase
CSC58_RS11510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC58_RS11510	COG2190	(PTS) system
CSC58_RS11510	COG1263	PTS System
CSC58_RS11540	COG3189	MarR family transcriptional regulator
CSC58_RS11545	COG0747	negative chemotaxis
CSC58_RS11560	COG0318	PFAM AMP-dependent synthetase and ligase
CSC58_RS11565	COG1960	acyl-CoA dehydrogenase activity
CSC58_RS11575	COG0183	Belongs to the thiolase family
CSC58_RS11635	COG1755	Isoprenylcysteine carboxyl methyltransferase
CSC58_RS11645	COG0673	inositol 2-dehydrogenase activity
CSC58_RS11650	COG0673	inositol 2-dehydrogenase activity
CSC58_RS11655	COG3833	ABC-type maltose transport systems, permease component
CSC58_RS11660	COG1175	transmembrane transport
CSC58_RS11670	COG3842	ATPase activity
CSC58_RS11690	COG0405	Gamma-glutamyltransferase
CSC58_RS11700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC58_RS11705	COG0601	transmembrane transport
CSC58_RS11740	COG1737	Transcriptional regulator
CSC58_RS11770	COG3961	Belongs to the TPP enzyme family
CSC58_RS11775	COG1335	isochorismatase
CSC58_RS11780	COG1114	Component of the transport system for branched-chain amino acids
CSC58_RS11830	COG5609	conserved protein (DUF2294)
CSC58_RS11835	COG1960	acyl-CoA dehydrogenase activity
CSC58_RS11840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC58_RS11875	COG2832	Protein of unknown function (DUF454)
CSC58_RS11885	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSC58_RS11890	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSC58_RS11900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSC58_RS11930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSC58_RS11940	COG1086	Polysaccharide biosynthesis protein
CSC58_RS11965	COG1012	belongs to the aldehyde dehydrogenase family
CSC58_RS11965	COG1454	alcohol dehydrogenase
CSC58_RS12010	COG0737	Belongs to the 5'-nucleotidase family
CSC58_RS12030	COG3639	organic phosphonate transmembrane transporter activity
CSC58_RS12050	COG2814	Major facilitator Superfamily
CSC58_RS12055	COG0813	purine-nucleoside phosphorylase activity
CSC58_RS12090	COG0438	transferase activity, transferring glycosyl groups
CSC58_RS12095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSC58_RS12100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC58_RS12130	COG1475	DNA binding
CSC58_RS12135	COG0019	diaminopimelate decarboxylase activity
CSC58_RS12145	COG4264	IucA IucC family
CSC58_RS12150	COG4264	IucA IucC family
CSC58_RS12155	COG2814	Major facilitator Superfamily
CSC58_RS12160	COG4264	IucA IucC family
CSC58_RS12165	COG2423	ornithine cyclodeaminase activity
CSC58_RS12175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSC58_RS12180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC58_RS12185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC58_RS12200	COG1388	LysM domain
CSC58_RS12205	COG1620	l-lactate permease
CSC58_RS12220	COG0697	spore germination
CSC58_RS12225	COG4716	Myosin-crossreactive antigen
CSC58_RS12230	COG1283	sodium-dependent phosphate transmembrane transporter activity
CSC58_RS12245	COG1473	amidohydrolase
CSC58_RS12275	COG0823	Involved in the tonB-independent uptake of proteins
CSC58_RS12285	COG2226	methyltransferase
CSC58_RS12300	COG1073	alpha beta
CSC58_RS12350	COG1332	CRISPR-associated RAMP protein, Csm5 family
CSC58_RS12355	COG1567	CRISPR-associated RAMP protein, Csm4 family
CSC58_RS12360	COG1337	RAMP superfamily
CSC58_RS12365	COG1421	Csm2 Type III-A
CSC58_RS12370	COG1353	crispr-associated protein
CSC58_RS12375	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CSC58_RS12420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CSC58_RS12470	COG2030	dehydratase
CSC58_RS12475	COG0584	glycerophosphoryl diester phosphodiesterase
CSC58_RS12485	COG3425	synthase
CSC58_RS12525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC58_RS12525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC58_RS12555	COG0737	Belongs to the 5'-nucleotidase family
CSC58_RS12560	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CSC58_RS12570	COG4863	YycH protein
CSC58_RS12605	COG0305	Participates in initiation and elongation during chromosome replication
CSC58_RS12615	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CSC58_RS12625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSC58_RS12655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSC58_RS12675	COG2501	S4 domain
CSC58_RS12715	COG1475	DNA binding
CSC58_RS12740	COG1278	Cold shock
CSC58_RS12750	COG0577	efflux transmembrane transporter activity
CSC58_RS12755	COG1136	(ABC) transporter
CSC58_RS12770	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CSC58_RS12780	COG2962	Rard protein
CSC58_RS12785	COG0471	metal ion transport
CSC58_RS12860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CSC58_RS12890	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CSC58_RS12945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC58_RS12965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC58_RS12985	COG1073	alpha beta
CSC58_RS13000	COG0438	transferase activity, transferring glycosyl groups
CSC58_RS13015	COG3433	isochorismatase activity
CSC58_RS13015	COG1535	isochorismatase
CSC58_RS13020	COG3942	CHAP domain
CSC58_RS13020	COG1705	Flagellar rod assembly protein muramidase FlgJ
CSC58_RS13030	COG1482	cell wall glycoprotein biosynthetic process
CSC58_RS13035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC58_RS13035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC58_RS13035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC58_RS13040	COG3711	transcriptional antiterminator
CSC58_RS13040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC58_RS13060	COG1438	arginine binding
CSC58_RS13105	COG1846	Transcriptional regulator
CSC58_RS13115	COG1785	Belongs to the alkaline phosphatase family
CSC58_RS13125	COG0745	RESPONSE REGULATOR receiver
CSC58_RS13130	COG2205	protein histidine kinase activity
CSC58_RS13135	COG1136	(ABC) transporter
CSC58_RS13160	COG0386	Belongs to the glutathione peroxidase family
CSC58_RS13170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CSC58_RS13185	COG2851	Citrate transporter
CSC58_RS13210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC58_RS13215	COG1510	regulation of RNA biosynthetic process
CSC58_RS13225	COG1012	belongs to the aldehyde dehydrogenase family
CSC58_RS13245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSC58_RS13275	COG0531	amino acid
CSC58_RS13285	COG3527	Alpha-acetolactate decarboxylase
CSC58_RS13290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSC58_RS13345	COG0167	dihydroorotate dehydrogenase activity
CSC58_RS13350	COG3001	Fructosamine kinase
CSC58_RS13390	COG0596	Alpha beta hydrolase
CSC58_RS13460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CSC58_RS13460	COG2755	lipolytic protein G-D-S-L family
CSC58_RS13465	COG3942	CHAP domain
CSC58_RS13495	COG0436	Aminotransferase
CSC58_RS13540	COG2409	Drug exporters of the RND superfamily
CSC58_RS13565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSC58_RS13570	COG3425	synthase
CSC58_RS13580	COG3942	CHAP domain
CSC58_RS13590	COG0583	DNA-binding transcription factor activity
CSC58_RS13605	COG0028	Belongs to the TPP enzyme family
CSC58_RS13625	COG0657	acetylesterase activity
CSC58_RS13630	COG0697	spore germination
CSC58_RS13645	COG1760	l-serine dehydratase
CSC58_RS13650	COG1760	l-serine dehydratase
CSC58_RS13670	COG3764	Sortase (surface protein transpeptidase)
CSC58_RS13680	COG1131	(ABC) transporter
CSC58_RS13685	COG0561	phosphatase activity
CSC58_RS13700	COG2514	catechol 2,3-dioxygenase activity
CSC58_RS13710	COG1846	Transcriptional regulator
CSC58_RS13715	COG0346	lactoylglutathione lyase activity
CSC58_RS13720	COG0400	carboxylic ester hydrolase activity
CSC58_RS13740	COG1131	(ABC) transporter
CSC58_RS13755	COG0586	Pfam SNARE associated Golgi protein
CSC58_RS13760	COG2271	Major facilitator Superfamily
CSC58_RS13775	COG4876	unkown
CSC58_RS13780	COG2357	RelA SpoT domain protein
CSC58_RS13785	COG0789	Transcriptional regulator
CSC58_RS13790	COG1802	Transcriptional regulator
CSC58_RS13795	COG1070	Carbohydrate kinase
CSC58_RS13830	COG1846	Transcriptional regulator
CSC58_RS13870	COG0494	nUDIX hydrolase
CSC58_RS13975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSC58_RS13980	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CSC58_RS13985	COG1028	Short-chain dehydrogenase reductase Sdr
CSC58_RS14030	COG1124	(ABC) transporter
CSC58_RS14045	COG0069	glutamate synthase activity
CSC58_RS14050	COG4808	Protein conserved in bacteria
CSC58_RS14070	COG1363	Peptidase, m42
CSC58_RS14075	COG4619	ABC transporter
CSC58_RS14080	COG0390	transport system, permease component
CSC58_RS14085	COG2814	Major facilitator Superfamily
CSC58_RS14090	COG2272	Belongs to the type-B carboxylesterase lipase family
CSC58_RS14095	COG0531	amino acid
CSC58_RS14105	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CSC58_RS14135	COG1174	glycine betaine transport
CSC58_RS14145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSC58_RS14170	COG0531	amino acid
CSC58_RS14185	COG1113	amino acid transport
CSC58_RS14205	COG2814	Major facilitator Superfamily
CSC58_RS14215	COG1929	Belongs to the glycerate kinase type-1 family
CSC58_RS14235	COG2375	cellular response to nickel ion
CSC58_RS14235	COG1132	(ABC) transporter
CSC58_RS14240	COG1132	(ABC) transporter
CSC58_RS14255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CSC58_RS14260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSC58_RS14270	COG0156	8-amino-7-oxononanoate synthase activity
CSC58_RS14320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSC58_RS14340	COG2814	Major facilitator Superfamily
CSC58_RS14345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC58_RS14350	COG0765	amino acid transport
CSC58_RS14355	COG1126	abc transporter atp-binding protein
CSC58_RS14390	COG3443	Belongs to the bacterial solute-binding protein 9 family
CSC58_RS14390	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSC58_RS14405	COG2116	formate transmembrane transporter activity
CSC58_RS14410	COG0454	-acetyltransferase
CSC58_RS14420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSC58_RS14425	COG2146	nitrite reductase [NAD(P)H] activity
CSC58_RS14435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CSC58_RS14440	COG1140	nitrate reductase beta subunit
CSC58_RS14450	COG2181	nitrate reductase activity
CSC58_RS14500	COG3871	stress protein (general stress protein 26)
CSC58_RS14515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC58_RS14515	COG1263	PTS System
CSC58_RS14530	COG1511	domain protein
CSC58_RS14555	COG0456	acetyltransferase
CSC58_RS14565	COG0604	alcohol dehydrogenase
CSC58_RS14585	COG1620	l-lactate permease
CSC58_RS14650	COG2814	Major facilitator Superfamily
CSC58_RS14660	COG1566	PFAM secretion protein HlyD family protein
CSC58_RS14665	COG2814	Major facilitator Superfamily
CSC58_RS14675	COG0657	acetylesterase activity
CSC58_RS14690	COG0598	Magnesium transport protein CorA
CSC58_RS14700	COG0786	glutamate:sodium symporter activity
CSC58_RS14720	COG3152	Membrane
CSC58_RS14725	COG4152	abc transporter atp-binding protein
CSC58_RS14730	COG1668	transmembrane transport