locus-tag	class	description
D1F65_RS00015	COG2501	S4 domain
D1F65_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D1F65_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D1F65_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D1F65_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
D1F65_RS00120	COG4863	YycH protein
D1F65_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D1F65_RS00135	COG0737	Belongs to the 5'-nucleotidase family
D1F65_RS00190	COG0584	glycerophosphoryl diester phosphodiesterase
D1F65_RS00195	COG2030	dehydratase
D1F65_RS00220	COG1940	carbohydrate kinase activity
D1F65_RS00220	COG1846	Transcriptional regulator
D1F65_RS00230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D1F65_RS00235	COG2210	Belongs to the sulfur carrier protein TusA family
D1F65_RS00240	COG1937	Protein conserved in bacteria
D1F65_RS00245	COG0730	response to heat
D1F65_RS00255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D1F65_RS00295	COG2003	Belongs to the UPF0758 family
D1F65_RS00350	COG0745	RESPONSE REGULATOR receiver
D1F65_RS00355	COG2205	protein histidine kinase activity
D1F65_RS00430	COG0730	response to heat
D1F65_RS00435	COG1937	Protein conserved in bacteria
D1F65_RS00440	COG2210	Belongs to the sulfur carrier protein TusA family
D1F65_RS00445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D1F65_RS00500	COG0823	Involved in the tonB-independent uptake of proteins
D1F65_RS00535	COG1473	amidohydrolase
D1F65_RS00545	COG1283	sodium-dependent phosphate transmembrane transporter activity
D1F65_RS00550	COG4716	Myosin-crossreactive antigen
D1F65_RS00555	COG0697	spore germination
D1F65_RS00570	COG1620	l-lactate permease
D1F65_RS00590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1F65_RS00595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1F65_RS00600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D1F65_RS00610	COG2423	ornithine cyclodeaminase activity
D1F65_RS00615	COG4264	IucA IucC family
D1F65_RS00620	COG2814	Major facilitator Superfamily
D1F65_RS00625	COG4264	IucA IucC family
D1F65_RS00630	COG4264	IucA IucC family
D1F65_RS00640	COG0019	diaminopimelate decarboxylase activity
D1F65_RS00645	COG1475	DNA binding
D1F65_RS00670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D1F65_RS00675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D1F65_RS00680	COG0438	transferase activity, transferring glycosyl groups
D1F65_RS00715	COG0813	purine-nucleoside phosphorylase activity
D1F65_RS00720	COG2814	Major facilitator Superfamily
D1F65_RS00740	COG3639	organic phosphonate transmembrane transporter activity
D1F65_RS00760	COG0737	Belongs to the 5'-nucleotidase family
D1F65_RS00775	COG1454	alcohol dehydrogenase
D1F65_RS00775	COG1012	belongs to the aldehyde dehydrogenase family
D1F65_RS00800	COG1086	Polysaccharide biosynthesis protein
D1F65_RS00810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D1F65_RS00840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D1F65_RS00850	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D1F65_RS00855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D1F65_RS00865	COG2832	Protein of unknown function (DUF454)
D1F65_RS00900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D1F65_RS00905	COG1960	acyl-CoA dehydrogenase activity
D1F65_RS00910	COG5609	conserved protein (DUF2294)
D1F65_RS00960	COG1114	Component of the transport system for branched-chain amino acids
D1F65_RS00965	COG1335	isochorismatase
D1F65_RS00970	COG3961	Belongs to the TPP enzyme family
D1F65_RS01000	COG1737	Transcriptional regulator
D1F65_RS01025	COG1136	(ABC) transporter
D1F65_RS01030	COG1136	(ABC) transporter
D1F65_RS01030	COG0577	efflux transmembrane transporter activity
D1F65_RS01050	COG1131	(ABC) transporter
D1F65_RS01065	COG0601	transmembrane transport
D1F65_RS01070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1F65_RS01080	COG0405	Gamma-glutamyltransferase
D1F65_RS01100	COG3842	ATPase activity
D1F65_RS01110	COG1175	transmembrane transport
D1F65_RS01115	COG3833	ABC-type maltose transport systems, permease component
D1F65_RS01120	COG0673	inositol 2-dehydrogenase activity
D1F65_RS01125	COG0673	inositol 2-dehydrogenase activity
D1F65_RS01135	COG1755	Isoprenylcysteine carboxyl methyltransferase
D1F65_RS01190	COG0183	Belongs to the thiolase family
D1F65_RS01200	COG1960	acyl-CoA dehydrogenase activity
D1F65_RS01205	COG0318	PFAM AMP-dependent synthetase and ligase
D1F65_RS01220	COG0747	negative chemotaxis
D1F65_RS01225	COG3189	MarR family transcriptional regulator
D1F65_RS01260	COG2190	(PTS) system
D1F65_RS01260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1F65_RS01260	COG1263	PTS System
D1F65_RS01265	COG1957	nucleoside hydrolase
D1F65_RS01285	COG3414	Phosphotransferase system galactitol-specific IIB component
D1F65_RS01290	COG3775	system Galactitol-specific IIC component
D1F65_RS01295	COG1063	alcohol dehydrogenase
D1F65_RS01305	COG1063	alcohol dehydrogenase
D1F65_RS01315	COG1063	alcohol dehydrogenase
D1F65_RS01320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D1F65_RS01325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D1F65_RS01335	COG1063	alcohol dehydrogenase
D1F65_RS01340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D1F65_RS01375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D1F65_RS01385	COG2190	(PTS) system
D1F65_RS01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1F65_RS01385	COG1263	PTS System
D1F65_RS01390	COG2723	6-phospho-beta-galactosidase activity
D1F65_RS01400	COG2226	methyltransferase
D1F65_RS01455	COG1131	(ABC) transporter
D1F65_RS01475	COG1388	LysM domain
D1F65_RS01475	COG3942	CHAP domain
D1F65_RS01595	COG1114	Component of the transport system for branched-chain amino acids
D1F65_RS01605	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
D1F65_RS01615	COG0577	efflux transmembrane transporter activity
D1F65_RS01645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D1F65_RS01650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D1F65_RS01675	COG3314	Sporulation integral membrane protein YlbJ
D1F65_RS01700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1F65_RS01730	COG3037	sugar-specific permease SgaT UlaA
D1F65_RS01740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1F65_RS01745	COG3711	transcriptional antiterminator
D1F65_RS01770	COG2271	Major facilitator Superfamily
D1F65_RS01775	COG0346	lactoylglutathione lyase activity
D1F65_RS01780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1F65_RS01785	COG0431	NADPH-dependent FMN reductase
D1F65_RS01800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D1F65_RS01805	COG2822	iron ion transport
D1F65_RS01815	COG0672	)-iron permease
D1F65_RS01820	COG0805	protein transport
D1F65_RS01825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D1F65_RS01835	COG1476	TRANSCRIPTIONal
D1F65_RS01845	COG1131	(ABC) transporter
D1F65_RS01875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D1F65_RS01875	COG0646	methionine synthase
D1F65_RS01880	COG0626	cystathionine gamma-synthase activity
D1F65_RS01885	COG0626	cystathionine gamma-synthase activity
D1F65_RS01895	COG1475	DNA binding
D1F65_RS01900	COG0668	transmembrane transport
D1F65_RS01905	COG4481	Protein conserved in bacteria
D1F65_RS01910	COG0012	GTP binding
D1F65_RS02015	COG1823	symporter activity
D1F65_RS02050	COG2233	PERMEase
D1F65_RS02090	COG3759	membrane
D1F65_RS02250	COG0523	cobalamin synthesis protein
D1F65_RS02275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D1F65_RS02285	COG5609	conserved protein (DUF2294)
D1F65_RS02300	COG1647	Serine aminopeptidase, S33
D1F65_RS02305	COG0733	neurotransmitter:sodium symporter activity
D1F65_RS02310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D1F65_RS02315	COG0626	cystathionine gamma-synthase activity
D1F65_RS02325	COG2011	ABC-type metal ion transport system permease component
D1F65_RS02330	COG1464	Belongs to the NlpA lipoprotein family
D1F65_RS02365	COG0583	DNA-binding transcription factor activity
D1F65_RS02370	COG0069	glutamate synthase activity
D1F65_RS02370	COG0067	glutamate synthase
D1F65_RS02370	COG0070	glutamate synthase
D1F65_RS02375	COG0493	'glutamate synthase
D1F65_RS02385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1F65_RS02385	COG1263	PTS System
D1F65_RS02390	COG0366	Alpha amylase catalytic
D1F65_RS02395	COG2188	Transcriptional regulator
D1F65_RS02415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D1F65_RS02455	COG1982	Orn Lys Arg decarboxylase major
D1F65_RS02465	COG3870	Protein conserved in bacteria
D1F65_RS02470	COG0470	DNA polymerase III
D1F65_RS02475	COG1774	PSP1 C-terminal conserved region
D1F65_RS02485	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D1F65_RS02495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D1F65_RS02505	COG0084	hydrolase, TatD family'
D1F65_RS02510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D1F65_RS02520	COG4466	Protein conserved in bacteria
D1F65_RS02530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D1F65_RS02535	COG0251	oxidation-reduction process
D1F65_RS02580	COG2244	polysaccharide biosynthetic process
D1F65_RS02585	COG3956	TIGRFAM MazG family protein
D1F65_RS02590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D1F65_RS02600	COG1098	S1 RNA binding domain
D1F65_RS02615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D1F65_RS02640	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D1F65_RS02735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D1F65_RS02750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D1F65_RS02760	COG3880	PFAM UvrB UvrC protein
D1F65_RS02775	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D1F65_RS02780	COG4956	integral membrane protein (PIN domain superfamily)
D1F65_RS02805	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D1F65_RS02865	COG2813	Specifically methylates the guanine in position
D1F65_RS02905	COG1473	amidohydrolase
D1F65_RS02935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D1F65_RS02940	COG1428	Deoxynucleoside kinase
D1F65_RS02945	COG1428	Deoxynucleoside kinase
D1F65_RS02955	COG0561	phosphatase activity
D1F65_RS03000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D1F65_RS03015	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D1F65_RS03115	COG0095	Lipoate-protein ligase
D1F65_RS03120	COG0083	homoserine kinase activity
D1F65_RS03140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D1F65_RS03170	COG0667	Aldo Keto reductase
D1F65_RS03180	COG0655	NAD(P)H dehydrogenase (quinone) activity
D1F65_RS03190	COG1078	dGTPase activity
D1F65_RS03225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D1F65_RS03230	COG4139	cobalamin transport
D1F65_RS03280	COG4974	Belongs to the 'phage' integrase family
D1F65_RS03335	COG0803	Belongs to the bacterial solute-binding protein 9 family
D1F65_RS03340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D1F65_RS03345	COG1121	(ABC) transporter
D1F65_RS03350	COG1321	iron dependent repressor
D1F65_RS03360	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D1F65_RS03370	COG1682	transport, permease protein
D1F65_RS03375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D1F65_RS03385	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D1F65_RS03390	COG1686	Belongs to the peptidase S11 family
D1F65_RS03395	COG1132	(ABC) transporter
D1F65_RS03400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D1F65_RS03410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D1F65_RS03415	COG1120	ATPase activity
D1F65_RS03420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1F65_RS03425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1F65_RS03430	COG2376	Dihydroxyacetone kinase
D1F65_RS03440	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
D1F65_RS03450	COG3949	Membrane
D1F65_RS03475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D1F65_RS03490	COG1136	(ABC) transporter
D1F65_RS03495	COG0577	efflux transmembrane transporter activity
D1F65_RS03510	COG1392	Phosphate transport regulator
D1F65_RS03515	COG0306	phosphate transporter
D1F65_RS03520	COG3942	CHAP domain
D1F65_RS03520	COG1388	LysM domain
D1F65_RS03530	COG1917	Cupin 2, conserved barrel domain protein
D1F65_RS03530	COG4977	sequence-specific DNA binding
D1F65_RS03560	COG0583	DNA-binding transcription factor activity
D1F65_RS03565	COG2814	Major facilitator Superfamily
D1F65_RS03570	COG2839	Protein conserved in bacteria
D1F65_RS03600	COG1611	Belongs to the LOG family
D1F65_RS03620	COG4988	ABC transporter
D1F65_RS03625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D1F65_RS03635	COG0523	cobalamin synthesis protein
D1F65_RS03640	COG4989	oxidoreductase activity
D1F65_RS03650	COG0471	metal ion transport
D1F65_RS03655	COG0415	Belongs to the DNA photolyase family
D1F65_RS03685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D1F65_RS03690	COG1349	DNA-binding transcription factor activity
D1F65_RS03695	COG1105	Belongs to the carbohydrate kinase PfkB family
D1F65_RS03700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1F65_RS03700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1F65_RS03700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1F65_RS03705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D1F65_RS03710	COG1253	flavin adenine dinucleotide binding
D1F65_RS03715	COG0656	L-ascorbic acid biosynthetic process
D1F65_RS03720	COG0463	Glycosyl transferase, family 2
D1F65_RS03755	COG0720	synthase
D1F65_RS03765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D1F65_RS03765	COG0512	Glutamine amidotransferase of anthranilate synthase
D1F65_RS03770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D1F65_RS03800	COG0488	(ABC) transporter
D1F65_RS03805	COG0514	ATP-dependent DNA helicase (RecQ)
D1F65_RS03810	COG0517	IMP dehydrogenase activity
D1F65_RS03810	COG1125	glycine betaine transport
D1F65_RS03815	COG1174	glycine betaine transport
D1F65_RS03850	COG3104	oligopeptide transport
D1F65_RS03880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D1F65_RS03885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D1F65_RS03895	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1F65_RS03900	COG4605	iron ion homeostasis
D1F65_RS03905	COG4604	ABC transporter, ATP-binding protein
D1F65_RS03910	COG4607	ABC-type enterochelin transport system periplasmic component
D1F65_RS03965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D1F65_RS03970	COG1739	Uncharacterized protein family UPF0029
D1F65_RS03980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D1F65_RS03985	COG1040	competence protein
D1F65_RS04015	COG3942	CHAP domain
D1F65_RS04015	COG1388	LysM domain
D1F65_RS04075	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D1F65_RS04145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D1F65_RS04150	COG1647	Serine aminopeptidase, S33
D1F65_RS04155	COG0557	exoribonuclease II activity
D1F65_RS04230	COG1278	Cold shock
D1F65_RS04270	COG0406	alpha-ribazole phosphatase activity
D1F65_RS04275	COG1279	arginine transmembrane transporter activity
D1F65_RS04300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D1F65_RS04305	COG1393	Belongs to the ArsC family
D1F65_RS04320	COG3878	Protein conserved in bacteria
D1F65_RS04330	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D1F65_RS04345	COG2011	ABC-type metal ion transport system permease component
D1F65_RS04350	COG1464	Belongs to the NlpA lipoprotein family
D1F65_RS04365	COG0396	ATPase activity
D1F65_RS04370	COG0719	Fe-S assembly protein
D1F65_RS04380	COG0822	iron-sulfur transferase activity
D1F65_RS04405	COG1253	flavin adenine dinucleotide binding
D1F65_RS04420	COG1801	Protein of unknown function DUF72
D1F65_RS04425	COG0730	response to heat
D1F65_RS04440	COG4470	Protein conserved in bacteria
D1F65_RS04460	COG2445	Protein of unknown function DUF86
D1F65_RS04490	COG1696	Membrane protein involved in D-alanine export
D1F65_RS04500	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D1F65_RS04505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D1F65_RS04510	COG4837	Protein of unknown function (DUF1462)
D1F65_RS04515	COG1252	NADH dehydrogenase
D1F65_RS04525	COG0316	Belongs to the HesB IscA family
D1F65_RS04535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D1F65_RS04540	COG2056	Na+-H+ antiporter family
D1F65_RS04545	COG2050	protein possibly involved in aromatic compounds catabolism
D1F65_RS04600	COG1098	S1 RNA binding domain
D1F65_RS04605	COG1902	pentaerythritol trinitrate reductase activity
D1F65_RS04620	COG0584	glycerophosphoryl diester phosphodiesterase
D1F65_RS04640	COG0398	Pfam SNARE associated Golgi protein
D1F65_RS04680	COG0561	phosphatase activity
D1F65_RS04705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D1F65_RS04720	COG1881	PFAM PEBP family protein
D1F65_RS04750	COG0601	transmembrane transport
D1F65_RS04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1F65_RS04760	COG0444	Belongs to the ABC transporter superfamily
D1F65_RS04765	COG4608	Belongs to the ABC transporter superfamily
D1F65_RS04770	COG4166	transmembrane transport
D1F65_RS04775	COG0747	negative chemotaxis
D1F65_RS04780	COG0444	Belongs to the ABC transporter superfamily
D1F65_RS04785	COG4608	Belongs to the ABC transporter superfamily
D1F65_RS04790	COG0601	transmembrane transport
D1F65_RS04795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1F65_RS04820	COG1164	Oligoendopeptidase f
D1F65_RS04830	COG2346	COG2346, Truncated hemoglobins
D1F65_RS04845	COG2357	RelA SpoT domain protein
D1F65_RS04855	COG0564	pseudouridine synthase activity
D1F65_RS04860	COG2239	Acts as a magnesium transporter
D1F65_RS04865	COG0569	domain protein
D1F65_RS04865	COG0475	glutathione-regulated potassium exporter activity
D1F65_RS04875	COG0628	permease
D1F65_RS04880	COG1115	amino acid carrier protein
D1F65_RS04920	COG0861	Integral membrane protein TerC family
D1F65_RS04930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D1F65_RS04935	COG0737	Belongs to the 5'-nucleotidase family
D1F65_RS04960	COG4903	ComK protein
D1F65_RS04975	COG4873	Protein conserved in bacteria
D1F65_RS05030	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D1F65_RS05040	COG2314	TM2 domain
D1F65_RS05045	COG0456	acetyltransferase
D1F65_RS05050	COG1575	Belongs to the MenA family. Type 1 subfamily
D1F65_RS05060	COG1169	isochorismate synthase
D1F65_RS05070	COG2267	carboxylic ester hydrolase activity
D1F65_RS05095	COG0436	Aminotransferase
D1F65_RS05100	COG3594	Acyltransferase
D1F65_RS05130	COG1316	TRANSCRIPTIONal
D1F65_RS05175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D1F65_RS05190	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D1F65_RS05230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D1F65_RS05235	COG4172	Belongs to the ABC transporter superfamily
D1F65_RS05240	COG4721	ABC-type cobalt transport system, permease component
D1F65_RS05265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D1F65_RS05285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D1F65_RS05290	COG1271	oxidase subunit
D1F65_RS05295	COG1294	oxidase, subunit
D1F65_RS05300	COG0569	domain protein
D1F65_RS05365	COG1176	ABC-type spermidine putrescine transport system, permease component I
D1F65_RS05370	COG1177	transmembrane transport
D1F65_RS05375	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D1F65_RS05400	COG0483	inositol monophosphate 1-phosphatase activity
D1F65_RS05410	COG1217	gtp-binding protein TYPA
D1F65_RS05420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D1F65_RS05430	COG0772	Belongs to the SEDS family
D1F65_RS05470	COG3679	Belongs to the UPF0342 family
D1F65_RS05490	COG0742	ribosomal rna small subunit methyltransferase
D1F65_RS05800	COG1388	LysM domain
D1F65_RS05800	COG0860	N-Acetylmuramoyl-L-alanine amidase
D1F65_RS05855	COG4509	Sortase family
D1F65_RS05870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D1F65_RS05915	COG1796	DNA polymerase
D1F65_RS05915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D1F65_RS05940	COG2009	succinate dehydrogenase
D1F65_RS05945	COG1053	succinate dehydrogenase
D1F65_RS05950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D1F65_RS06080	COG1288	antiporter activity
D1F65_RS06115	COG1011	Hydrolase
D1F65_RS06140	COG4839	cell division protein FtsL
D1F65_RS06145	COG0768	penicillin binding
D1F65_RS06160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D1F65_RS06165	COG0849	cell division
D1F65_RS06180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D1F65_RS06190	COG0762	integral membrane protein
D1F65_RS06200	COG3599	regulation of cell shape
D1F65_RS06210	COG2514	catechol 2,3-dioxygenase activity
D1F65_RS06230	COG0564	pseudouridine synthase activity
D1F65_RS06240	COG2233	PERMEase
D1F65_RS06285	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D1F65_RS06300	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D1F65_RS06305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D1F65_RS06315	COG2314	TM2 domain
D1F65_RS06330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D1F65_RS06330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D1F65_RS06340	COG0631	protein serine/threonine phosphatase activity
D1F65_RS06355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D1F65_RS06370	COG1302	Protein conserved in bacteria
D1F65_RS06420	COG1196	nuclear chromosome segregation
D1F65_RS06425	COG0552	protein localization to endoplasmic reticulum
D1F65_RS06435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D1F65_RS06490	COG2348	transferase activity, transferring amino-acyl groups
D1F65_RS06495	COG0758	DNA mediated transformation
D1F65_RS06500	COG0758	DNA mediated transformation
D1F65_RS06600	COG0195	Participates in both transcription termination and antitermination
D1F65_RS06605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D1F65_RS06630	COG0196	riboflavin kinase activity
D1F65_RS06660	COG2188	Transcriptional regulator
D1F65_RS06665	COG0612	Peptidase, M16
D1F65_RS06670	COG0612	Peptidase, M16
D1F65_RS06675	COG0300	oxidoreductase activity
D1F65_RS06695	COG1058	Belongs to the CinA family
D1F65_RS06695	COG1546	Belongs to the CinA family
D1F65_RS06715	COG1692	metallophosphoesterase
D1F65_RS06720	COG0674	pyruvate-flavodoxin oxidoreductase activity
D1F65_RS06720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D1F65_RS06725	COG1013	pyruvate-flavodoxin oxidoreductase activity
D1F65_RS06760	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D1F65_RS06765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D1F65_RS06790	COG1923	regulation of RNA biosynthetic process
D1F65_RS06800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D1F65_RS06805	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D1F65_RS06810	COG0789	Transcriptional regulator
D1F65_RS06895	COG1131	(ABC) transporter
D1F65_RS06910	COG2197	response regulator
D1F65_RS06920	COG1525	nuclease
D1F65_RS06935	COG0527	aspartate kinase activity
D1F65_RS06940	COG0460	homoserine dehydrogenase
D1F65_RS06945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D1F65_RS06970	COG0833	amino acid
D1F65_RS07000	COG2340	Cysteine-rich secretory protein family
D1F65_RS07035	COG4846	Membrane protein involved in cytochrome C biogenesis
D1F65_RS07055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D1F65_RS07070	COG0824	Thioesterase
D1F65_RS07110	COG1115	amino acid carrier protein
D1F65_RS07125	COG0628	permease
D1F65_RS07150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D1F65_RS07160	COG1363	Peptidase, m42
D1F65_RS07165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D1F65_RS07170	COG0512	Glutamine amidotransferase of anthranilate synthase
D1F65_RS07215	COG0561	phosphatase activity
D1F65_RS07260	COG0704	Plays a role in the regulation of phosphate uptake
D1F65_RS07270	COG0581	inorganic phosphate transmembrane transporter activity
D1F65_RS07275	COG0573	inorganic phosphate transmembrane transporter activity
D1F65_RS07295	COG0488	(ABC) transporter
D1F65_RS07305	COG0527	aspartate kinase activity
D1F65_RS07310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D1F65_RS07385	COG4548	von Willebrand factor, type A
D1F65_RS07390	COG0714	Associated with various cellular activities
D1F65_RS07435	COG0671	phosphoesterase, PA-phosphatase related
D1F65_RS07510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D1F65_RS07530	COG0531	amino acid
D1F65_RS07545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D1F65_RS07550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D1F65_RS07565	COG0116	Belongs to the methyltransferase superfamily
D1F65_RS07605	COG4499	WXG100 protein secretion system (Wss), protein YukC
D1F65_RS07605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D1F65_RS07615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D1F65_RS07620	COG3935	DnaD domain protein
D1F65_RS07645	COG0438	transferase activity, transferring glycosyl groups
D1F65_RS07650	COG1694	Mazg nucleotide pyrophosphohydrolase
D1F65_RS07655	COG2738	Putative neutral zinc metallopeptidase
D1F65_RS07660	COG4347	Protein of unknown function (DUF1405)
D1F65_RS07700	COG0142	geranyltranstransferase activity
D1F65_RS07765	COG0492	ferredoxin-NADP+ reductase activity
D1F65_RS07780	COG0514	ATP-dependent DNA helicase (RecQ)
D1F65_RS07790	COG1141	Ferredoxin
D1F65_RS07845	COG0745	RESPONSE REGULATOR receiver
D1F65_RS07850	COG1187	pseudouridine synthase activity
D1F65_RS07875	COG0735	belongs to the Fur family
D1F65_RS07880	COG0494	nUDIX hydrolase
D1F65_RS07885	COG0667	Aldo Keto reductase
D1F65_RS07895	COG4221	oxidoreductase activity
D1F65_RS07910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D1F65_RS07920	COG0366	Alpha amylase catalytic
D1F65_RS07925	COG1609	Transcriptional regulator
D1F65_RS07950	COG2195	Cleaves the N-terminal amino acid of tripeptides
D1F65_RS07960	COG4129	membrane
D1F65_RS07970	COG0508	dehydrogenase complex catalyzes the overall conversion of
D1F65_RS07975	COG0022	dehydrogenase e1 component
D1F65_RS07980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D1F65_RS07985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D1F65_RS07990	COG0497	DNA recombination
D1F65_RS08020	COG1302	Protein conserved in bacteria
D1F65_RS08025	COG0439	Biotin carboxylase
D1F65_RS08030	COG0511	ligase activity, forming carbon-carbon bonds
D1F65_RS08040	COG0006	proline dipeptidase activity
D1F65_RS08055	COG0095	Lipoate-protein ligase
D1F65_RS08060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D1F65_RS08105	COG4537	Required for transformation and DNA binding
D1F65_RS08110	COG1459	type II secretion system
D1F65_RS08115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D1F65_RS08120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D1F65_RS08125	COG0011	TIGRFAM Protein of
D1F65_RS08130	COG1940	carbohydrate kinase activity
D1F65_RS08135	COG4483	Protein conserved in bacteria
D1F65_RS08145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D1F65_RS08155	COG0768	penicillin binding
D1F65_RS08170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D1F65_RS08175	COG1121	(ABC) transporter
D1F65_RS08185	COG0513	Belongs to the DEAD box helicase family
D1F65_RS08195	COG2384	SAM-dependent methyltransferase
D1F65_RS08215	COG0517	IMP dehydrogenase activity
D1F65_RS08235	COG0295	cytidine deaminase activity
D1F65_RS08250	COG1702	phosphate starvation-inducible protein PhoH
D1F65_RS08265	COG1030	water channel activity
D1F65_RS08275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D1F65_RS08280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D1F65_RS08310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D1F65_RS08325	COG1466	dna polymerase III delta subunit
D1F65_RS08330	COG0658	competence protein
D1F65_RS08330	COG2333	competence protein COMEC
D1F65_RS08335	COG2131	deaminase
D1F65_RS08340	COG2183	response to ionizing radiation
D1F65_RS08345	COG2226	methyltransferase
D1F65_RS08350	COG0799	negative regulation of ribosome biogenesis
D1F65_RS08355	COG1713	HD superfamily hydrolase involved in NAD metabolism
D1F65_RS08365	COG1534	Rna-binding protein
D1F65_RS08375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D1F65_RS08380	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D1F65_RS08410	COG3177	Filamentation induced by cAMP protein fic
D1F65_RS08420	COG1914	H( )-stimulated, divalent metal cation uptake system
D1F65_RS08430	COG0439	Biotin carboxylase
D1F65_RS08435	COG0511	ligase activity, forming carbon-carbon bonds
D1F65_RS08440	COG1984	allophanate hydrolase subunit 2
D1F65_RS08445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D1F65_RS08460	COG0826	peptidase U32
D1F65_RS08465	COG0826	peptidase U32
D1F65_RS08495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D1F65_RS08520	COG1104	cysteine desulfurase activity
D1F65_RS08525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1F65_RS08535	COG3237	CsbD-like
D1F65_RS08540	COG1959	2 iron, 2 sulfur cluster binding
D1F65_RS08545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D1F65_RS08550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D1F65_RS08595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D1F65_RS08595	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D1F65_RS08600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D1F65_RS08600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D1F65_RS08605	COG1862	Preprotein translocase
D1F65_RS08645	COG2868	ribosomal protein
D1F65_RS08690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D1F65_RS08735	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D1F65_RS08745	COG0285	dihydrofolate synthase activity
D1F65_RS08755	COG2818	Glycosylase
D1F65_RS08790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D1F65_RS08825	COG4112	unkown
D1F65_RS08850	COG0833	amino acid
D1F65_RS08865	COG1484	DNA-dependent DNA replication
D1F65_RS08895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D1F65_RS08895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D1F65_RS08905	COG5002	protein histidine kinase activity
D1F65_RS08910	COG0745	RESPONSE REGULATOR receiver
D1F65_RS08925	COG0372	Belongs to the citrate synthase family
D1F65_RS08930	COG1113	amino acid transport
D1F65_RS08955	COG0281	malic enzyme
D1F65_RS08965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D1F65_RS08970	COG4109	DRTGG domain
D1F65_RS09010	COG0827	DNA restriction-modification system
D1F65_RS09020	COG0730	response to heat
D1F65_RS09030	COG1104	cysteine desulfurase activity
D1F65_RS09045	COG1956	GAF domain-containing protein
D1F65_RS09065	COG0584	glycerophosphoryl diester phosphodiesterase
D1F65_RS09070	COG1764	response to oxidative stress
D1F65_RS09075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D1F65_RS09080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D1F65_RS09095	COG1263	PTS System
D1F65_RS09095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1F65_RS09100	COG0204	Acyl-transferase
D1F65_RS09105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D1F65_RS09140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D1F65_RS09145	COG0454	-acetyltransferase
D1F65_RS09165	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D1F65_RS09165	COG1605	Chorismate mutase
D1F65_RS09190	COG1674	ftsk spoiiie
D1F65_RS09195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D1F65_RS09205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D1F65_RS09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D1F65_RS09230	COG0510	thiamine kinase activity
D1F65_RS09250	COG1187	pseudouridine synthase activity
D1F65_RS09255	COG2244	polysaccharide biosynthetic process
D1F65_RS09280	COG2814	Major facilitator Superfamily
D1F65_RS09285	COG1242	4 iron, 4 sulfur cluster binding
D1F65_RS09290	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D1F65_RS09300	COG2267	carboxylic ester hydrolase activity
D1F65_RS09335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D1F65_RS09335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D1F65_RS09355	COG3266	domain, Protein
D1F65_RS09355	COG4193	domain, Protein
D1F65_RS09355	COG5632	N-Acetylmuramoyl-L-alanine amidase
D1F65_RS09385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D1F65_RS09410	COG0656	L-ascorbic acid biosynthetic process
D1F65_RS09430	COG1506	peptidase
D1F65_RS09435	COG2816	NAD+ diphosphatase activity
D1F65_RS09700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D1F65_RS09730	COG1131	(ABC) transporter
D1F65_RS09735	COG0537	adenosine 5'-monophosphoramidase activity
D1F65_RS09765	COG0420	3'-5' exonuclease activity
D1F65_RS09795	COG2197	response regulator
D1F65_RS09800	COG4585	Histidine kinase
D1F65_RS09800	COG2203	Gaf domain
D1F65_RS09805	COG0564	pseudouridine synthase activity
D1F65_RS09835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D1F65_RS09840	COG1126	abc transporter atp-binding protein
D1F65_RS09845	COG0765	amino acid transport
D1F65_RS10015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D1F65_RS10020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1F65_RS10030	COG4129	membrane
D1F65_RS10055	COG1988	membrane-bound metal-dependent
D1F65_RS10070	COG1388	LysM domain
D1F65_RS10070	COG1134	teichoic acid transport
D1F65_RS10100	COG0535	radical SAM domain protein
D1F65_RS10105	COG1607	acyl-coa hydrolase
D1F65_RS10110	COG2309	aminopeptidase activity
D1F65_RS10130	COG1295	ribonuclease BN
D1F65_RS10250	COG4851	CamS sex pheromone cAM373 precursor
D1F65_RS10270	COG4496	protein, YerC YecD
D1F65_RS10310	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D1F65_RS10320	COG0077	Prephenate dehydratase
D1F65_RS10330	COG0471	metal ion transport
D1F65_RS10340	COG1335	isochorismatase
D1F65_RS10355	COG1012	belongs to the aldehyde dehydrogenase family
D1F65_RS10410	COG1131	(ABC) transporter
D1F65_RS10425	COG1725	Transcriptional regulator
D1F65_RS10475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D1F65_RS10545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1F65_RS10550	COG1621	beta-fructofuranosidase activity
D1F65_RS10555	COG1609	Transcriptional regulator
D1F65_RS10560	COG0004	ammonium transporteR
D1F65_RS10565	COG0425	Belongs to the sulfur carrier protein TusA family
D1F65_RS10570	COG2391	methyltransferase activity
D1F65_RS10580	COG0488	(ABC) transporter
D1F65_RS10590	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D1F65_RS10600	COG0456	acetyltransferase
D1F65_RS10605	COG1214	PFAM Peptidase M22, glycoprotease
D1F65_RS10610	COG0802	atpase or kinase
D1F65_RS10625	COG0028	Belongs to the TPP enzyme family
D1F65_RS10700	COG2183	response to ionizing radiation
D1F65_RS10705	COG1191	sigma factor activity
D1F65_RS10715	COG1366	Belongs to the anti-sigma-factor antagonist family
D1F65_RS10720	COG2208	phosphoserine phosphatase activity
D1F65_RS10755	COG3428	Bacterial PH domain
D1F65_RS10785	COG2205	protein histidine kinase activity
D1F65_RS10790	COG0745	RESPONSE REGULATOR receiver
D1F65_RS10810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D1F65_RS10820	COG0772	Belongs to the SEDS family
D1F65_RS10835	COG1937	Protein conserved in bacteria
D1F65_RS10845	COG1418	mRNA catabolic process
D1F65_RS10900	COG0629	single-stranded DNA binding
D1F65_RS10975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D1F65_RS11000	COG0009	L-threonylcarbamoyladenylate synthase
D1F65_RS11005	COG2890	protein-(glutamine-N5) methyltransferase activity
D1F65_RS11030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D1F65_RS11070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D1F65_RS11120	COG0813	purine-nucleoside phosphorylase activity
D1F65_RS11125	COG0783	Belongs to the Dps family
D1F65_RS11145	COG1482	cell wall glycoprotein biosynthetic process
D1F65_RS11150	COG0702	epimerase
D1F65_RS11155	COG0640	Transcriptional regulator
D1F65_RS11190	COG0561	phosphatase activity
D1F65_RS11195	COG1119	ATPase activity
D1F65_RS11210	COG3711	transcriptional antiterminator
D1F65_RS11240	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D1F65_RS11300	COG0489	protein tyrosine kinase activity
D1F65_RS11305	COG2814	Major facilitator Superfamily
D1F65_RS11320	COG1272	protein, Hemolysin III
D1F65_RS11330	COG1988	membrane-bound metal-dependent
D1F65_RS11340	COG3314	Sporulation integral membrane protein YlbJ
D1F65_RS11345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1F65_RS11350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1F65_RS11355	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D1F65_RS11365	COG3457	Alanine racemase
D1F65_RS11370	COG4264	IucA IucC family
D1F65_RS11375	COG2814	Major facilitator Superfamily
D1F65_RS11400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D1F65_RS11410	COG2130	NADP-dependent
D1F65_RS11475	COG0656	L-ascorbic acid biosynthetic process
D1F65_RS11480	COG0789	Transcriptional regulator
D1F65_RS11490	COG5492	domain, Protein
D1F65_RS11510	COG3527	Alpha-acetolactate decarboxylase
D1F65_RS11515	COG0028	Belongs to the TPP enzyme family
D1F65_RS11630	COG0201	protein transport
D1F65_RS11745	COG2252	PERMEase
D1F65_RS11795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D1F65_RS11865	COG1763	Mo-molybdopterin cofactor biosynthetic process
D1F65_RS11885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D1F65_RS11890	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D1F65_RS11895	COG4149	molybdate abc transporter
D1F65_RS11900	COG0725	ABC transporter, periplasmic molybdate-binding protein
D1F65_RS11915	COG1268	BioY protein
D1F65_RS11930	COG1960	acyl-CoA dehydrogenase activity
D1F65_RS11935	COG4413	Urea transporter
D1F65_RS12000	COG3942	CHAP domain
D1F65_RS12010	COG1757	Na H antiporter
D1F65_RS12025	COG3942	CHAP domain
D1F65_RS12095	COG1113	amino acid transport
D1F65_RS12115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1F65_RS12120	COG0385	Bile acid
D1F65_RS12135	COG1737	Transcriptional regulator
D1F65_RS12155	COG1028	Short-chain dehydrogenase reductase Sdr
D1F65_RS12160	COG1473	amidohydrolase
D1F65_RS12175	COG0583	DNA-binding transcription factor activity
D1F65_RS12200	COG2258	MOSC domain
D1F65_RS12225	COG4152	abc transporter atp-binding protein
D1F65_RS12230	COG3152	Membrane
D1F65_RS12250	COG0786	glutamate:sodium symporter activity
D1F65_RS12260	COG0598	Magnesium transport protein CorA
D1F65_RS12275	COG0657	acetylesterase activity
D1F65_RS12285	COG2814	Major facilitator Superfamily
D1F65_RS12290	COG1566	PFAM secretion protein HlyD family protein
D1F65_RS12300	COG2814	Major facilitator Superfamily
D1F65_RS12365	COG1620	l-lactate permease
D1F65_RS12385	COG0604	alcohol dehydrogenase
D1F65_RS12415	COG1511	domain protein
D1F65_RS12430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1F65_RS12430	COG1263	PTS System
D1F65_RS12445	COG3871	stress protein (general stress protein 26)
D1F65_RS12485	COG0789	Transcriptional regulator
D1F65_RS12505	COG2181	nitrate reductase activity
D1F65_RS12515	COG1140	nitrate reductase beta subunit
D1F65_RS12520	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D1F65_RS12530	COG2146	nitrite reductase [NAD(P)H] activity
D1F65_RS12535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D1F65_RS12545	COG0454	-acetyltransferase
D1F65_RS12550	COG2116	formate transmembrane transporter activity
D1F65_RS12565	COG3443	Belongs to the bacterial solute-binding protein 9 family
D1F65_RS12565	COG0803	Belongs to the bacterial solute-binding protein 9 family
D1F65_RS12605	COG1126	abc transporter atp-binding protein
D1F65_RS12610	COG0765	amino acid transport
D1F65_RS12615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1F65_RS12620	COG2814	Major facilitator Superfamily
D1F65_RS12640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D1F65_RS12695	COG0156	8-amino-7-oxononanoate synthase activity
D1F65_RS12705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D1F65_RS12710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D1F65_RS12725	COG1132	(ABC) transporter
D1F65_RS12730	COG1132	(ABC) transporter
D1F65_RS12730	COG2375	cellular response to nickel ion
D1F65_RS12750	COG1929	Belongs to the glycerate kinase type-1 family
D1F65_RS12760	COG2814	Major facilitator Superfamily
D1F65_RS12780	COG1113	amino acid transport
D1F65_RS12795	COG0531	amino acid
D1F65_RS12820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D1F65_RS12830	COG1174	glycine betaine transport
D1F65_RS12840	COG1174	glycine betaine transport
D1F65_RS12860	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D1F65_RS12870	COG0531	amino acid
D1F65_RS12875	COG2272	Belongs to the type-B carboxylesterase lipase family
D1F65_RS12880	COG2814	Major facilitator Superfamily
D1F65_RS12885	COG0390	transport system, permease component
D1F65_RS12890	COG4619	ABC transporter
D1F65_RS12895	COG1363	Peptidase, m42
D1F65_RS12915	COG4808	Protein conserved in bacteria
D1F65_RS12920	COG0069	glutamate synthase activity
D1F65_RS12975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D1F65_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
D1F65_RS12985	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D1F65_RS12990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D1F65_RS13085	COG0494	nUDIX hydrolase
D1F65_RS13130	COG1846	Transcriptional regulator
D1F65_RS13165	COG1070	Carbohydrate kinase
D1F65_RS13170	COG1802	Transcriptional regulator
D1F65_RS13175	COG0789	Transcriptional regulator
D1F65_RS13180	COG2357	RelA SpoT domain protein
D1F65_RS13185	COG4876	unkown
D1F65_RS13195	COG2271	Major facilitator Superfamily
D1F65_RS13200	COG0586	Pfam SNARE associated Golgi protein
D1F65_RS13220	COG1131	(ABC) transporter
D1F65_RS13240	COG0400	carboxylic ester hydrolase activity
D1F65_RS13245	COG0346	lactoylglutathione lyase activity
D1F65_RS13250	COG1846	Transcriptional regulator
D1F65_RS13260	COG2514	catechol 2,3-dioxygenase activity
D1F65_RS13275	COG0561	phosphatase activity
D1F65_RS13280	COG1131	(ABC) transporter
D1F65_RS13290	COG3764	Sortase (surface protein transpeptidase)
D1F65_RS13310	COG1760	l-serine dehydratase
D1F65_RS13315	COG1760	l-serine dehydratase
D1F65_RS13330	COG0697	spore germination
D1F65_RS13335	COG0657	acetylesterase activity
D1F65_RS13355	COG0028	Belongs to the TPP enzyme family
D1F65_RS13370	COG0583	DNA-binding transcription factor activity
D1F65_RS13380	COG3942	CHAP domain
D1F65_RS13390	COG3425	synthase
D1F65_RS13395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D1F65_RS13420	COG2409	Drug exporters of the RND superfamily
D1F65_RS13465	COG0436	Aminotransferase
D1F65_RS13495	COG3942	CHAP domain
D1F65_RS13500	COG2755	lipolytic protein G-D-S-L family
D1F65_RS13500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D1F65_RS13610	COG3001	Fructosamine kinase
D1F65_RS13615	COG0167	dihydroorotate dehydrogenase activity
D1F65_RS13670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D1F65_RS13675	COG3527	Alpha-acetolactate decarboxylase
D1F65_RS13690	COG0531	amino acid
D1F65_RS13720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D1F65_RS13740	COG1012	belongs to the aldehyde dehydrogenase family
D1F65_RS13750	COG1510	regulation of RNA biosynthetic process
D1F65_RS13755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D1F65_RS13780	COG2851	Citrate transporter
D1F65_RS13795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D1F65_RS13805	COG0386	Belongs to the glutathione peroxidase family
D1F65_RS13830	COG1136	(ABC) transporter
D1F65_RS13835	COG2205	protein histidine kinase activity
D1F65_RS13840	COG0745	RESPONSE REGULATOR receiver
D1F65_RS13850	COG1785	Belongs to the alkaline phosphatase family
D1F65_RS13860	COG1846	Transcriptional regulator
D1F65_RS13905	COG1438	arginine binding
D1F65_RS13925	COG3711	transcriptional antiterminator
D1F65_RS13925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1F65_RS13930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1F65_RS13930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1F65_RS13930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1F65_RS13935	COG1482	cell wall glycoprotein biosynthetic process
D1F65_RS13945	COG3942	CHAP domain
D1F65_RS13945	COG1705	Flagellar rod assembly protein muramidase FlgJ
D1F65_RS13950	COG3433	isochorismatase activity
D1F65_RS13950	COG1535	isochorismatase
D1F65_RS13965	COG0438	transferase activity, transferring glycosyl groups
D1F65_RS13980	COG1073	alpha beta
D1F65_RS14000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D1F65_RS14020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D1F65_RS14115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D1F65_RS14200	COG0471	metal ion transport
D1F65_RS14205	COG2962	Rard protein
D1F65_RS14215	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
D1F65_RS14230	COG1136	(ABC) transporter
D1F65_RS14235	COG0577	efflux transmembrane transporter activity
D1F65_RS14245	COG1278	Cold shock
D1F65_RS14265	COG1475	DNA binding