locus-tag	class	description
AB454_RS00015	COG2501	S4 domain
AB454_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AB454_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AB454_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB454_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AB454_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
AB454_RS00120	COG4863	YycH protein
AB454_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AB454_RS00135	COG0737	Belongs to the 5'-nucleotidase family
AB454_RS00185	COG0456	acetyltransferase
AB454_RS00200	COG0730	response to heat
AB454_RS00205	COG1937	Protein conserved in bacteria
AB454_RS00210	COG2210	Belongs to the sulfur carrier protein TusA family
AB454_RS00215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB454_RS00255	COG0655	NAD(P)H dehydrogenase (quinone) activity
AB454_RS00270	COG0583	DNA-binding transcription factor activity
AB454_RS00290	COG0823	Involved in the tonB-independent uptake of proteins
AB454_RS00335	COG1473	amidohydrolase
AB454_RS00345	COG1283	sodium-dependent phosphate transmembrane transporter activity
AB454_RS00350	COG4716	Myosin-crossreactive antigen
AB454_RS00360	COG1620	l-lactate permease
AB454_RS00380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB454_RS00385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB454_RS00390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AB454_RS00400	COG2423	ornithine cyclodeaminase activity
AB454_RS00405	COG4264	IucA IucC family
AB454_RS00410	COG2814	Major facilitator Superfamily
AB454_RS00415	COG4264	IucA IucC family
AB454_RS00420	COG4264	IucA IucC family
AB454_RS00430	COG0019	diaminopimelate decarboxylase activity
AB454_RS00435	COG1475	DNA binding
AB454_RS00465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB454_RS00470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB454_RS00475	COG0438	transferase activity, transferring glycosyl groups
AB454_RS00510	COG0813	purine-nucleoside phosphorylase activity
AB454_RS00515	COG2814	Major facilitator Superfamily
AB454_RS00535	COG3639	organic phosphonate transmembrane transporter activity
AB454_RS00555	COG0737	Belongs to the 5'-nucleotidase family
AB454_RS00585	COG1012	belongs to the aldehyde dehydrogenase family
AB454_RS00585	COG1454	alcohol dehydrogenase
AB454_RS00615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AB454_RS00645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB454_RS00655	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AB454_RS00660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AB454_RS00670	COG2832	Protein of unknown function (DUF454)
AB454_RS00710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB454_RS00715	COG1960	acyl-CoA dehydrogenase activity
AB454_RS00720	COG5609	conserved protein (DUF2294)
AB454_RS00770	COG1114	Component of the transport system for branched-chain amino acids
AB454_RS00775	COG1335	isochorismatase
AB454_RS00780	COG3961	Belongs to the TPP enzyme family
AB454_RS00810	COG1737	Transcriptional regulator
AB454_RS00835	COG1136	(ABC) transporter
AB454_RS00840	COG0577	efflux transmembrane transporter activity
AB454_RS00840	COG1136	(ABC) transporter
AB454_RS00860	COG1131	(ABC) transporter
AB454_RS00875	COG0601	transmembrane transport
AB454_RS00880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB454_RS00890	COG0405	Gamma-glutamyltransferase
AB454_RS00910	COG3842	ATPase activity
AB454_RS00920	COG1175	transmembrane transport
AB454_RS00925	COG3833	ABC-type maltose transport systems, permease component
AB454_RS00930	COG0673	inositol 2-dehydrogenase activity
AB454_RS00935	COG0673	inositol 2-dehydrogenase activity
AB454_RS00945	COG1755	Isoprenylcysteine carboxyl methyltransferase
AB454_RS01005	COG0183	Belongs to the thiolase family
AB454_RS01015	COG1960	acyl-CoA dehydrogenase activity
AB454_RS01020	COG0318	PFAM AMP-dependent synthetase and ligase
AB454_RS01035	COG0747	negative chemotaxis
AB454_RS01040	COG3189	MarR family transcriptional regulator
AB454_RS01070	COG2190	(PTS) system
AB454_RS01070	COG1263	PTS System
AB454_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB454_RS01075	COG1957	nucleoside hydrolase
AB454_RS01095	COG3414	Phosphotransferase system galactitol-specific IIB component
AB454_RS01100	COG3775	system Galactitol-specific IIC component
AB454_RS01105	COG1063	alcohol dehydrogenase
AB454_RS01115	COG1063	alcohol dehydrogenase
AB454_RS01125	COG1063	alcohol dehydrogenase
AB454_RS01130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AB454_RS01140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AB454_RS01150	COG1063	alcohol dehydrogenase
AB454_RS01155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AB454_RS01190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB454_RS01200	COG1263	PTS System
AB454_RS01200	COG2190	(PTS) system
AB454_RS01200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB454_RS01205	COG2723	6-phospho-beta-galactosidase activity
AB454_RS01220	COG2226	methyltransferase
AB454_RS01270	COG1131	(ABC) transporter
AB454_RS01290	COG3942	CHAP domain
AB454_RS01290	COG1388	LysM domain
AB454_RS01420	COG1114	Component of the transport system for branched-chain amino acids
AB454_RS01430	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AB454_RS01440	COG0577	efflux transmembrane transporter activity
AB454_RS01470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AB454_RS01475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB454_RS01500	COG3314	Sporulation integral membrane protein YlbJ
AB454_RS01525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB454_RS01555	COG3037	sugar-specific permease SgaT UlaA
AB454_RS01565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB454_RS01570	COG3711	transcriptional antiterminator
AB454_RS01595	COG2271	Major facilitator Superfamily
AB454_RS01600	COG0346	lactoylglutathione lyase activity
AB454_RS01605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB454_RS01610	COG0431	NADPH-dependent FMN reductase
AB454_RS01625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB454_RS01640	COG0672	)-iron permease
AB454_RS01645	COG0805	protein transport
AB454_RS01650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AB454_RS01660	COG1476	TRANSCRIPTIONal
AB454_RS01670	COG1131	(ABC) transporter
AB454_RS01700	COG0646	methionine synthase
AB454_RS01700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AB454_RS01705	COG0626	cystathionine gamma-synthase activity
AB454_RS01710	COG0626	cystathionine gamma-synthase activity
AB454_RS01720	COG1475	DNA binding
AB454_RS01725	COG0668	transmembrane transport
AB454_RS01730	COG4481	Protein conserved in bacteria
AB454_RS01735	COG0012	GTP binding
AB454_RS01840	COG1823	symporter activity
AB454_RS01875	COG2233	PERMEase
AB454_RS01955	COG1683	Conserved Protein
AB454_RS01965	COG3759	membrane
AB454_RS02100	COG0523	cobalamin synthesis protein
AB454_RS02130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB454_RS02140	COG5609	conserved protein (DUF2294)
AB454_RS02155	COG1647	Serine aminopeptidase, S33
AB454_RS02165	COG0733	neurotransmitter:sodium symporter activity
AB454_RS02170	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AB454_RS02175	COG0626	cystathionine gamma-synthase activity
AB454_RS02185	COG2011	ABC-type metal ion transport system permease component
AB454_RS02190	COG1464	Belongs to the NlpA lipoprotein family
AB454_RS02225	COG0583	DNA-binding transcription factor activity
AB454_RS02230	COG0067	glutamate synthase
AB454_RS02230	COG0069	glutamate synthase activity
AB454_RS02230	COG0070	glutamate synthase
AB454_RS02235	COG0493	'glutamate synthase
AB454_RS02245	COG1263	PTS System
AB454_RS02245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB454_RS02250	COG0366	Alpha amylase catalytic
AB454_RS02255	COG2188	Transcriptional regulator
AB454_RS02275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AB454_RS02310	COG1982	Orn Lys Arg decarboxylase major
AB454_RS02320	COG3870	Protein conserved in bacteria
AB454_RS02325	COG0470	DNA polymerase III
AB454_RS02330	COG1774	PSP1 C-terminal conserved region
AB454_RS02340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AB454_RS02350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AB454_RS02360	COG0084	hydrolase, TatD family'
AB454_RS02365	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AB454_RS02375	COG4466	Protein conserved in bacteria
AB454_RS02385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AB454_RS02390	COG0251	oxidation-reduction process
AB454_RS02435	COG2244	polysaccharide biosynthetic process
AB454_RS02440	COG3956	TIGRFAM MazG family protein
AB454_RS02445	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AB454_RS02455	COG1098	S1 RNA binding domain
AB454_RS02470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB454_RS02495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AB454_RS02590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB454_RS02605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AB454_RS02615	COG3880	PFAM UvrB UvrC protein
AB454_RS02630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AB454_RS02635	COG4956	integral membrane protein (PIN domain superfamily)
AB454_RS02660	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AB454_RS02720	COG2813	Specifically methylates the guanine in position
AB454_RS02760	COG1473	amidohydrolase
AB454_RS02790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AB454_RS02795	COG1428	Deoxynucleoside kinase
AB454_RS02800	COG1428	Deoxynucleoside kinase
AB454_RS02810	COG0561	phosphatase activity
AB454_RS02855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AB454_RS02970	COG0095	Lipoate-protein ligase
AB454_RS02975	COG0083	homoserine kinase activity
AB454_RS02995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB454_RS03085	COG0667	Aldo Keto reductase
AB454_RS03090	COG0655	NAD(P)H dehydrogenase (quinone) activity
AB454_RS03100	COG1078	dGTPase activity
AB454_RS03135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AB454_RS03140	COG4139	cobalamin transport
AB454_RS03190	COG4974	Belongs to the 'phage' integrase family
AB454_RS03235	COG0803	Belongs to the bacterial solute-binding protein 9 family
AB454_RS03240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB454_RS03245	COG1121	(ABC) transporter
AB454_RS03250	COG1321	iron dependent repressor
AB454_RS03260	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AB454_RS03270	COG1682	transport, permease protein
AB454_RS03275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AB454_RS03285	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AB454_RS03290	COG1686	Belongs to the peptidase S11 family
AB454_RS03295	COG1132	(ABC) transporter
AB454_RS03300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AB454_RS03310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB454_RS03315	COG1120	ATPase activity
AB454_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB454_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB454_RS03330	COG2376	Dihydroxyacetone kinase
AB454_RS03340	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AB454_RS03350	COG3949	Membrane
AB454_RS03375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB454_RS03390	COG1136	(ABC) transporter
AB454_RS03395	COG0577	efflux transmembrane transporter activity
AB454_RS03400	COG1392	Phosphate transport regulator
AB454_RS03405	COG0306	phosphate transporter
AB454_RS03410	COG3942	CHAP domain
AB454_RS03410	COG1388	LysM domain
AB454_RS03420	COG1917	Cupin 2, conserved barrel domain protein
AB454_RS03420	COG4977	sequence-specific DNA binding
AB454_RS03450	COG0583	DNA-binding transcription factor activity
AB454_RS03455	COG2814	Major facilitator Superfamily
AB454_RS03460	COG2839	Protein conserved in bacteria
AB454_RS03490	COG1611	Belongs to the LOG family
AB454_RS03510	COG4988	ABC transporter
AB454_RS03515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AB454_RS03530	COG4989	oxidoreductase activity
AB454_RS03540	COG0471	metal ion transport
AB454_RS03545	COG0415	Belongs to the DNA photolyase family
AB454_RS03575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB454_RS03580	COG1349	DNA-binding transcription factor activity
AB454_RS03585	COG1105	Belongs to the carbohydrate kinase PfkB family
AB454_RS03590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB454_RS03590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB454_RS03590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB454_RS03595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AB454_RS03600	COG1253	flavin adenine dinucleotide binding
AB454_RS03605	COG0656	L-ascorbic acid biosynthetic process
AB454_RS03610	COG0463	Glycosyl transferase, family 2
AB454_RS03645	COG0720	synthase
AB454_RS03655	COG0512	Glutamine amidotransferase of anthranilate synthase
AB454_RS03655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AB454_RS03660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AB454_RS03690	COG0488	(ABC) transporter
AB454_RS03695	COG0514	ATP-dependent DNA helicase (RecQ)
AB454_RS03700	COG1125	glycine betaine transport
AB454_RS03700	COG0517	IMP dehydrogenase activity
AB454_RS03705	COG1174	glycine betaine transport
AB454_RS03735	COG3104	oligopeptide transport
AB454_RS03765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB454_RS03770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB454_RS03785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB454_RS03790	COG4605	iron ion homeostasis
AB454_RS03795	COG4604	ABC transporter, ATP-binding protein
AB454_RS03800	COG4607	ABC-type enterochelin transport system periplasmic component
AB454_RS03855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB454_RS03860	COG1739	Uncharacterized protein family UPF0029
AB454_RS03870	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AB454_RS03875	COG1040	competence protein
AB454_RS03905	COG1388	LysM domain
AB454_RS03905	COG3942	CHAP domain
AB454_RS03965	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AB454_RS04035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AB454_RS04040	COG1647	Serine aminopeptidase, S33
AB454_RS04045	COG0557	exoribonuclease II activity
AB454_RS04065	COG0582	viral genome integration into host DNA
AB454_RS04195	COG1278	Cold shock
AB454_RS04235	COG0406	alpha-ribazole phosphatase activity
AB454_RS04240	COG1279	arginine transmembrane transporter activity
AB454_RS04265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB454_RS04270	COG1393	Belongs to the ArsC family
AB454_RS04285	COG3878	Protein conserved in bacteria
AB454_RS04295	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AB454_RS04310	COG2011	ABC-type metal ion transport system permease component
AB454_RS04315	COG1464	Belongs to the NlpA lipoprotein family
AB454_RS04330	COG0396	ATPase activity
AB454_RS04335	COG0719	Fe-S assembly protein
AB454_RS04345	COG0822	iron-sulfur transferase activity
AB454_RS04370	COG1253	flavin adenine dinucleotide binding
AB454_RS04380	COG1801	Protein of unknown function DUF72
AB454_RS04385	COG0730	response to heat
AB454_RS04400	COG4470	Protein conserved in bacteria
AB454_RS04410	COG2445	Protein of unknown function DUF86
AB454_RS04440	COG1696	Membrane protein involved in D-alanine export
AB454_RS04450	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AB454_RS04455	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AB454_RS04460	COG4837	Protein of unknown function (DUF1462)
AB454_RS04465	COG1252	NADH dehydrogenase
AB454_RS04475	COG0316	Belongs to the HesB IscA family
AB454_RS04485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AB454_RS04490	COG2056	Na+-H+ antiporter family
AB454_RS04495	COG2050	protein possibly involved in aromatic compounds catabolism
AB454_RS04550	COG1098	S1 RNA binding domain
AB454_RS04555	COG1902	pentaerythritol trinitrate reductase activity
AB454_RS04570	COG0584	glycerophosphoryl diester phosphodiesterase
AB454_RS04630	COG0561	phosphatase activity
AB454_RS04655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB454_RS04670	COG1881	PFAM PEBP family protein
AB454_RS04700	COG0601	transmembrane transport
AB454_RS04705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB454_RS04710	COG0444	Belongs to the ABC transporter superfamily
AB454_RS04715	COG4608	Belongs to the ABC transporter superfamily
AB454_RS04720	COG4166	transmembrane transport
AB454_RS04725	COG0747	negative chemotaxis
AB454_RS04730	COG0444	Belongs to the ABC transporter superfamily
AB454_RS04735	COG4608	Belongs to the ABC transporter superfamily
AB454_RS04740	COG0601	transmembrane transport
AB454_RS04745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB454_RS04770	COG1164	Oligoendopeptidase f
AB454_RS04780	COG2346	COG2346, Truncated hemoglobins
AB454_RS04795	COG2357	RelA SpoT domain protein
AB454_RS04805	COG0564	pseudouridine synthase activity
AB454_RS04810	COG2239	Acts as a magnesium transporter
AB454_RS04815	COG0475	glutathione-regulated potassium exporter activity
AB454_RS04815	COG0569	domain protein
AB454_RS04825	COG0628	permease
AB454_RS04830	COG1115	amino acid carrier protein
AB454_RS04870	COG0861	Integral membrane protein TerC family
AB454_RS04880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AB454_RS04885	COG0737	Belongs to the 5'-nucleotidase family
AB454_RS04900	COG4903	ComK protein
AB454_RS04915	COG4873	Protein conserved in bacteria
AB454_RS04975	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AB454_RS04985	COG2314	TM2 domain
AB454_RS04990	COG0456	acetyltransferase
AB454_RS04995	COG1575	Belongs to the MenA family. Type 1 subfamily
AB454_RS05005	COG1169	isochorismate synthase
AB454_RS05015	COG2267	carboxylic ester hydrolase activity
AB454_RS05040	COG0436	Aminotransferase
AB454_RS05045	COG3594	Acyltransferase
AB454_RS05075	COG1316	TRANSCRIPTIONal
AB454_RS05120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AB454_RS05135	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB454_RS05165	COG0138	bifunctional purine biosynthesis protein purh
AB454_RS05175	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AB454_RS05180	COG4172	Belongs to the ABC transporter superfamily
AB454_RS05185	COG4721	ABC-type cobalt transport system, permease component
AB454_RS05210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AB454_RS05230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AB454_RS05235	COG1271	oxidase subunit
AB454_RS05240	COG1294	oxidase, subunit
AB454_RS05245	COG0569	domain protein
AB454_RS05310	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB454_RS05315	COG1177	transmembrane transport
AB454_RS05320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AB454_RS05345	COG0483	inositol monophosphate 1-phosphatase activity
AB454_RS05355	COG1217	gtp-binding protein TYPA
AB454_RS05365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AB454_RS05375	COG0772	Belongs to the SEDS family
AB454_RS05410	COG3679	Belongs to the UPF0342 family
AB454_RS05430	COG0742	ribosomal rna small subunit methyltransferase
AB454_RS05490	COG4509	Sortase family
AB454_RS05505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB454_RS05540	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AB454_RS05540	COG1796	DNA polymerase
AB454_RS05565	COG2009	succinate dehydrogenase
AB454_RS05570	COG1053	succinate dehydrogenase
AB454_RS05575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AB454_RS05695	COG1288	antiporter activity
AB454_RS05755	COG4839	cell division protein FtsL
AB454_RS05760	COG0768	penicillin binding
AB454_RS05775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AB454_RS05795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AB454_RS05805	COG0762	integral membrane protein
AB454_RS05810	COG2302	S4 RNA-binding domain
AB454_RS05815	COG3599	regulation of cell shape
AB454_RS05825	COG2514	catechol 2,3-dioxygenase activity
AB454_RS05840	COG0564	pseudouridine synthase activity
AB454_RS05850	COG2233	PERMEase
AB454_RS05895	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AB454_RS05910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AB454_RS05915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AB454_RS05925	COG2314	TM2 domain
AB454_RS05940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB454_RS05940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AB454_RS05950	COG0631	protein serine/threonine phosphatase activity
AB454_RS05965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AB454_RS05980	COG1302	Protein conserved in bacteria
AB454_RS06030	COG1196	nuclear chromosome segregation
AB454_RS06035	COG0552	protein localization to endoplasmic reticulum
AB454_RS06045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AB454_RS06110	COG0758	DNA mediated transformation
AB454_RS06210	COG0195	Participates in both transcription termination and antitermination
AB454_RS06215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AB454_RS06240	COG0196	riboflavin kinase activity
AB454_RS06270	COG2188	Transcriptional regulator
AB454_RS06275	COG0612	Peptidase, M16
AB454_RS06280	COG0612	Peptidase, M16
AB454_RS06285	COG0300	oxidoreductase activity
AB454_RS06305	COG1546	Belongs to the CinA family
AB454_RS06305	COG1058	Belongs to the CinA family
AB454_RS06325	COG1692	metallophosphoesterase
AB454_RS06330	COG0674	pyruvate-flavodoxin oxidoreductase activity
AB454_RS06330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AB454_RS06335	COG1013	pyruvate-flavodoxin oxidoreductase activity
AB454_RS06370	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AB454_RS06375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AB454_RS06400	COG1923	regulation of RNA biosynthetic process
AB454_RS06410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB454_RS06415	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AB454_RS06420	COG0789	Transcriptional regulator
AB454_RS06530	COG1131	(ABC) transporter
AB454_RS06550	COG2197	response regulator
AB454_RS06560	COG1525	nuclease
AB454_RS06575	COG0527	aspartate kinase activity
AB454_RS06580	COG0460	homoserine dehydrogenase
AB454_RS06585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AB454_RS06610	COG0833	amino acid
AB454_RS06640	COG2340	Cysteine-rich secretory protein family
AB454_RS06675	COG4846	Membrane protein involved in cytochrome C biogenesis
AB454_RS06695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB454_RS06710	COG0824	Thioesterase
AB454_RS06740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AB454_RS06750	COG1115	amino acid carrier protein
AB454_RS06765	COG0628	permease
AB454_RS06790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB454_RS06800	COG1363	Peptidase, m42
AB454_RS06805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AB454_RS06810	COG0512	Glutamine amidotransferase of anthranilate synthase
AB454_RS06900	COG0704	Plays a role in the regulation of phosphate uptake
AB454_RS06910	COG0581	inorganic phosphate transmembrane transporter activity
AB454_RS06915	COG0573	inorganic phosphate transmembrane transporter activity
AB454_RS06935	COG0488	(ABC) transporter
AB454_RS06940	COG0527	aspartate kinase activity
AB454_RS06945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AB454_RS07025	COG4548	von Willebrand factor, type A
AB454_RS07030	COG0714	Associated with various cellular activities
AB454_RS07075	COG0671	phosphoesterase, PA-phosphatase related
AB454_RS07155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AB454_RS07180	COG0531	amino acid
AB454_RS07195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB454_RS07200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AB454_RS07220	COG0116	Belongs to the methyltransferase superfamily
AB454_RS07260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB454_RS07260	COG4499	WXG100 protein secretion system (Wss), protein YukC
AB454_RS07270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AB454_RS07275	COG3935	DnaD domain protein
AB454_RS07300	COG0438	transferase activity, transferring glycosyl groups
AB454_RS07305	COG1694	Mazg nucleotide pyrophosphohydrolase
AB454_RS07310	COG2738	Putative neutral zinc metallopeptidase
AB454_RS07315	COG4347	Protein of unknown function (DUF1405)
AB454_RS07355	COG0142	geranyltranstransferase activity
AB454_RS07410	COG0492	ferredoxin-NADP+ reductase activity
AB454_RS07425	COG0514	ATP-dependent DNA helicase (RecQ)
AB454_RS07435	COG1141	Ferredoxin
AB454_RS07470	COG5002	protein histidine kinase activity
AB454_RS07475	COG0745	RESPONSE REGULATOR receiver
AB454_RS07480	COG1187	pseudouridine synthase activity
AB454_RS07505	COG0735	belongs to the Fur family
AB454_RS07510	COG0494	nUDIX hydrolase
AB454_RS07515	COG0667	Aldo Keto reductase
AB454_RS07525	COG4221	oxidoreductase activity
AB454_RS07540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB454_RS07550	COG0366	Alpha amylase catalytic
AB454_RS07555	COG1609	Transcriptional regulator
AB454_RS07575	COG2195	Cleaves the N-terminal amino acid of tripeptides
AB454_RS07585	COG4129	membrane
AB454_RS07595	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB454_RS07600	COG0022	dehydrogenase e1 component
AB454_RS07605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AB454_RS07610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB454_RS07615	COG0497	DNA recombination
AB454_RS07645	COG1302	Protein conserved in bacteria
AB454_RS07650	COG0439	Biotin carboxylase
AB454_RS07655	COG0511	ligase activity, forming carbon-carbon bonds
AB454_RS07665	COG0006	proline dipeptidase activity
AB454_RS07680	COG0095	Lipoate-protein ligase
AB454_RS07685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB454_RS07730	COG4537	Required for transformation and DNA binding
AB454_RS07735	COG1459	type II secretion system
AB454_RS07740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB454_RS07745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB454_RS07750	COG0011	TIGRFAM Protein of
AB454_RS07755	COG1940	carbohydrate kinase activity
AB454_RS07760	COG4483	Protein conserved in bacteria
AB454_RS07770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AB454_RS07780	COG0768	penicillin binding
AB454_RS07795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB454_RS07800	COG1121	(ABC) transporter
AB454_RS07810	COG0513	Belongs to the DEAD box helicase family
AB454_RS07820	COG2384	SAM-dependent methyltransferase
AB454_RS07840	COG0517	IMP dehydrogenase activity
AB454_RS07860	COG0295	cytidine deaminase activity
AB454_RS07875	COG1702	phosphate starvation-inducible protein PhoH
AB454_RS07890	COG1030	water channel activity
AB454_RS07900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB454_RS07905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AB454_RS07935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AB454_RS07960	COG1466	dna polymerase III delta subunit
AB454_RS07965	COG0658	competence protein
AB454_RS07965	COG2333	competence protein COMEC
AB454_RS07970	COG2131	deaminase
AB454_RS07975	COG2183	response to ionizing radiation
AB454_RS07980	COG2226	methyltransferase
AB454_RS07985	COG0799	negative regulation of ribosome biogenesis
AB454_RS07990	COG1713	HD superfamily hydrolase involved in NAD metabolism
AB454_RS08000	COG1534	Rna-binding protein
AB454_RS08010	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AB454_RS08015	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AB454_RS08035	COG3177	Filamentation induced by cAMP protein fic
AB454_RS08040	COG1914	H( )-stimulated, divalent metal cation uptake system
AB454_RS08050	COG0439	Biotin carboxylase
AB454_RS08055	COG0511	ligase activity, forming carbon-carbon bonds
AB454_RS08060	COG1984	allophanate hydrolase subunit 2
AB454_RS08065	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AB454_RS08080	COG0826	peptidase U32
AB454_RS08085	COG0826	peptidase U32
AB454_RS08115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB454_RS08135	COG1104	cysteine desulfurase activity
AB454_RS08140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB454_RS08150	COG3237	CsbD-like
AB454_RS08155	COG1959	2 iron, 2 sulfur cluster binding
AB454_RS08160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB454_RS08165	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AB454_RS08210	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AB454_RS08210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AB454_RS08215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB454_RS08215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB454_RS08220	COG1862	Preprotein translocase
AB454_RS08260	COG2868	ribosomal protein
AB454_RS08305	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AB454_RS08315	COG0285	dihydrofolate synthase activity
AB454_RS08325	COG2818	Glycosylase
AB454_RS08360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB454_RS08395	COG4112	unkown
AB454_RS08420	COG0833	amino acid
AB454_RS08435	COG1484	DNA-dependent DNA replication
AB454_RS08465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB454_RS08465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB454_RS08475	COG5002	protein histidine kinase activity
AB454_RS08480	COG0745	RESPONSE REGULATOR receiver
AB454_RS08495	COG0372	Belongs to the citrate synthase family
AB454_RS08500	COG1113	amino acid transport
AB454_RS08525	COG0281	malic enzyme
AB454_RS08535	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AB454_RS08550	COG4109	DRTGG domain
AB454_RS08590	COG0827	DNA restriction-modification system
AB454_RS08600	COG0730	response to heat
AB454_RS08610	COG1104	cysteine desulfurase activity
AB454_RS08625	COG1956	GAF domain-containing protein
AB454_RS08645	COG0584	glycerophosphoryl diester phosphodiesterase
AB454_RS08650	COG1764	response to oxidative stress
AB454_RS08655	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB454_RS08660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB454_RS08675	COG1263	PTS System
AB454_RS08675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB454_RS08680	COG0204	Acyl-transferase
AB454_RS08685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB454_RS08720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB454_RS08725	COG0454	-acetyltransferase
AB454_RS08745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AB454_RS08745	COG1605	Chorismate mutase
AB454_RS08770	COG1674	ftsk spoiiie
AB454_RS08775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB454_RS08785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB454_RS08790	COG1363	Peptidase, m42
AB454_RS08800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB454_RS08810	COG0510	thiamine kinase activity
AB454_RS08830	COG1187	pseudouridine synthase activity
AB454_RS08835	COG2244	polysaccharide biosynthetic process
AB454_RS08840	COG2081	HI0933 family
AB454_RS08860	COG2814	Major facilitator Superfamily
AB454_RS08865	COG1242	4 iron, 4 sulfur cluster binding
AB454_RS08870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AB454_RS08880	COG2267	carboxylic ester hydrolase activity
AB454_RS08915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB454_RS08915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB454_RS08935	COG3266	domain, Protein
AB454_RS08935	COG4193	domain, Protein
AB454_RS08935	COG5632	N-Acetylmuramoyl-L-alanine amidase
AB454_RS08965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AB454_RS08990	COG0656	L-ascorbic acid biosynthetic process
AB454_RS09010	COG1506	peptidase
AB454_RS09015	COG2816	NAD+ diphosphatase activity
AB454_RS09175	COG1131	(ABC) transporter
AB454_RS09295	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AB454_RS09325	COG1131	(ABC) transporter
AB454_RS09330	COG0537	adenosine 5'-monophosphoramidase activity
AB454_RS09365	COG0420	3'-5' exonuclease activity
AB454_RS09395	COG2197	response regulator
AB454_RS09400	COG2203	Gaf domain
AB454_RS09400	COG4585	Histidine kinase
AB454_RS09405	COG0564	pseudouridine synthase activity
AB454_RS09440	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AB454_RS09445	COG1126	abc transporter atp-binding protein
AB454_RS09450	COG0765	amino acid transport
AB454_RS09615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB454_RS09620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB454_RS09630	COG4129	membrane
AB454_RS09655	COG1988	membrane-bound metal-dependent
AB454_RS09670	COG1134	teichoic acid transport
AB454_RS09670	COG1388	LysM domain
AB454_RS09700	COG0535	radical SAM domain protein
AB454_RS09705	COG1607	acyl-coa hydrolase
AB454_RS09710	COG2309	aminopeptidase activity
AB454_RS09730	COG1295	ribonuclease BN
AB454_RS09860	COG4851	CamS sex pheromone cAM373 precursor
AB454_RS09870	COG0210	DNA helicase
AB454_RS09880	COG4496	protein, YerC YecD
AB454_RS09920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AB454_RS09930	COG0077	Prephenate dehydratase
AB454_RS09950	COG1335	isochorismatase
AB454_RS09965	COG1012	belongs to the aldehyde dehydrogenase family
AB454_RS10020	COG1131	(ABC) transporter
AB454_RS10035	COG1725	Transcriptional regulator
AB454_RS10090	COG1388	LysM domain
AB454_RS10090	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB454_RS10115	COG5632	N-Acetylmuramoyl-L-alanine amidase
AB454_RS10115	COG1388	LysM domain
AB454_RS10165	COG0739	heme binding
AB454_RS10220	COG4695	Portal protein
AB454_RS10415	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AB454_RS10420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AB454_RS10425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AB454_RS10445	COG5484	DNA packaging
AB454_RS10445	COG3728	DNA packaging
AB454_RS10525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB454_RS10530	COG1621	beta-fructofuranosidase activity
AB454_RS10535	COG1609	Transcriptional regulator
AB454_RS10540	COG0004	ammonium transporteR
AB454_RS10545	COG0425	Belongs to the sulfur carrier protein TusA family
AB454_RS10550	COG2391	methyltransferase activity
AB454_RS10560	COG0488	(ABC) transporter
AB454_RS10570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AB454_RS10580	COG0456	acetyltransferase
AB454_RS10585	COG1214	PFAM Peptidase M22, glycoprotease
AB454_RS10590	COG0802	atpase or kinase
AB454_RS10605	COG0028	Belongs to the TPP enzyme family
AB454_RS10680	COG2183	response to ionizing radiation
AB454_RS10685	COG1191	sigma factor activity
AB454_RS10695	COG1366	Belongs to the anti-sigma-factor antagonist family
AB454_RS10700	COG2208	phosphoserine phosphatase activity
AB454_RS10735	COG3428	Bacterial PH domain
AB454_RS10765	COG2205	protein histidine kinase activity
AB454_RS10770	COG0745	RESPONSE REGULATOR receiver
AB454_RS10780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AB454_RS10790	COG0772	Belongs to the SEDS family
AB454_RS10805	COG1937	Protein conserved in bacteria
AB454_RS10815	COG1418	mRNA catabolic process
AB454_RS10865	COG0629	single-stranded DNA binding
AB454_RS10940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AB454_RS10965	COG0009	L-threonylcarbamoyladenylate synthase
AB454_RS10970	COG2890	protein-(glutamine-N5) methyltransferase activity
AB454_RS10995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AB454_RS11035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB454_RS11085	COG0813	purine-nucleoside phosphorylase activity
AB454_RS11090	COG0783	Belongs to the Dps family
AB454_RS11110	COG1482	cell wall glycoprotein biosynthetic process
AB454_RS11115	COG0702	epimerase
AB454_RS11120	COG0640	Transcriptional regulator
AB454_RS11155	COG0561	phosphatase activity
AB454_RS11160	COG1119	ATPase activity
AB454_RS11175	COG3711	transcriptional antiterminator
AB454_RS11205	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AB454_RS11265	COG0489	protein tyrosine kinase activity
AB454_RS11270	COG2814	Major facilitator Superfamily
AB454_RS11285	COG1272	protein, Hemolysin III
AB454_RS11295	COG1988	membrane-bound metal-dependent
AB454_RS11305	COG3314	Sporulation integral membrane protein YlbJ
AB454_RS11310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB454_RS11315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB454_RS11320	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AB454_RS11330	COG3457	Alanine racemase
AB454_RS11335	COG4264	IucA IucC family
AB454_RS11340	COG2814	Major facilitator Superfamily
AB454_RS11375	COG2130	NADP-dependent
AB454_RS11440	COG0656	L-ascorbic acid biosynthetic process
AB454_RS11445	COG0789	Transcriptional regulator
AB454_RS11455	COG5492	domain, Protein
AB454_RS11465	COG3527	Alpha-acetolactate decarboxylase
AB454_RS11470	COG0028	Belongs to the TPP enzyme family
AB454_RS11545	COG0201	protein transport
AB454_RS11660	COG2252	PERMEase
AB454_RS11705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB454_RS11770	COG1763	Mo-molybdopterin cofactor biosynthetic process
AB454_RS11790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AB454_RS11795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AB454_RS11800	COG4149	molybdate abc transporter
AB454_RS11805	COG0725	ABC transporter, periplasmic molybdate-binding protein
AB454_RS11820	COG1268	BioY protein
AB454_RS11835	COG1960	acyl-CoA dehydrogenase activity
AB454_RS11840	COG4413	Urea transporter
AB454_RS11915	COG1757	Na H antiporter
AB454_RS11930	COG3942	CHAP domain
AB454_RS12010	COG1113	amino acid transport
AB454_RS12030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB454_RS12035	COG0385	Bile acid
AB454_RS12045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB454_RS12045	COG1263	PTS System
AB454_RS12050	COG1737	Transcriptional regulator
AB454_RS12070	COG1028	Short-chain dehydrogenase reductase Sdr
AB454_RS12075	COG1473	amidohydrolase
AB454_RS12090	COG0583	DNA-binding transcription factor activity
AB454_RS12110	COG2258	MOSC domain
AB454_RS12130	COG1668	transmembrane transport
AB454_RS12135	COG4152	abc transporter atp-binding protein
AB454_RS12140	COG3152	Membrane
AB454_RS12155	COG0786	glutamate:sodium symporter activity
AB454_RS12165	COG0598	Magnesium transport protein CorA
AB454_RS12180	COG0657	acetylesterase activity
AB454_RS12190	COG2814	Major facilitator Superfamily
AB454_RS12195	COG1566	PFAM secretion protein HlyD family protein
AB454_RS12205	COG2814	Major facilitator Superfamily
AB454_RS12270	COG1620	l-lactate permease
AB454_RS12290	COG0604	alcohol dehydrogenase
AB454_RS12325	COG1511	domain protein
AB454_RS12340	COG1263	PTS System
AB454_RS12340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB454_RS12355	COG3871	stress protein (general stress protein 26)
AB454_RS12395	COG0789	Transcriptional regulator
AB454_RS12415	COG2181	nitrate reductase activity
AB454_RS12425	COG1140	nitrate reductase beta subunit
AB454_RS12430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AB454_RS12440	COG2146	nitrite reductase [NAD(P)H] activity
AB454_RS12445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB454_RS12455	COG0454	-acetyltransferase
AB454_RS12460	COG2116	formate transmembrane transporter activity
AB454_RS12475	COG0803	Belongs to the bacterial solute-binding protein 9 family
AB454_RS12475	COG3443	Belongs to the bacterial solute-binding protein 9 family
AB454_RS12510	COG1126	abc transporter atp-binding protein
AB454_RS12515	COG0765	amino acid transport
AB454_RS12520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB454_RS12525	COG2814	Major facilitator Superfamily
AB454_RS12545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AB454_RS12595	COG0156	8-amino-7-oxononanoate synthase activity
AB454_RS12605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AB454_RS12610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AB454_RS12625	COG1132	(ABC) transporter
AB454_RS12630	COG1132	(ABC) transporter
AB454_RS12630	COG2375	cellular response to nickel ion
AB454_RS12650	COG1929	Belongs to the glycerate kinase type-1 family
AB454_RS12660	COG2814	Major facilitator Superfamily
AB454_RS12680	COG1113	amino acid transport
AB454_RS12695	COG0531	amino acid
AB454_RS12720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AB454_RS12730	COG1174	glycine betaine transport
AB454_RS12740	COG1174	glycine betaine transport
AB454_RS12760	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AB454_RS12770	COG0531	amino acid
AB454_RS12775	COG2272	Belongs to the type-B carboxylesterase lipase family
AB454_RS12780	COG2814	Major facilitator Superfamily
AB454_RS12785	COG0390	transport system, permease component
AB454_RS12790	COG4619	ABC transporter
AB454_RS12795	COG1363	Peptidase, m42
AB454_RS12815	COG4808	Protein conserved in bacteria
AB454_RS12820	COG0069	glutamate synthase activity
AB454_RS12835	COG1124	(ABC) transporter
AB454_RS12840	COG0444	Belongs to the ABC transporter superfamily
AB454_RS12845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB454_RS12885	COG1028	Short-chain dehydrogenase reductase Sdr
AB454_RS12895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB454_RS12970	COG0494	nUDIX hydrolase
AB454_RS13015	COG1846	Transcriptional regulator
AB454_RS13050	COG1070	Carbohydrate kinase
AB454_RS13055	COG1802	Transcriptional regulator
AB454_RS13060	COG0789	Transcriptional regulator
AB454_RS13065	COG2357	RelA SpoT domain protein
AB454_RS13070	COG4876	unkown
AB454_RS13085	COG2271	Major facilitator Superfamily
AB454_RS13090	COG0586	Pfam SNARE associated Golgi protein
AB454_RS13105	COG1131	(ABC) transporter
AB454_RS13125	COG0400	carboxylic ester hydrolase activity
AB454_RS13130	COG0346	lactoylglutathione lyase activity
AB454_RS13135	COG1846	Transcriptional regulator
AB454_RS13145	COG2514	catechol 2,3-dioxygenase activity
AB454_RS13160	COG0561	phosphatase activity
AB454_RS13165	COG1131	(ABC) transporter
AB454_RS13175	COG3764	Sortase (surface protein transpeptidase)
AB454_RS13200	COG1760	l-serine dehydratase
AB454_RS13205	COG1760	l-serine dehydratase
AB454_RS13220	COG0697	spore germination
AB454_RS13225	COG0657	acetylesterase activity
AB454_RS13245	COG0028	Belongs to the TPP enzyme family
AB454_RS13260	COG0583	DNA-binding transcription factor activity
AB454_RS13270	COG3942	CHAP domain
AB454_RS13280	COG3425	synthase
AB454_RS13285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AB454_RS13310	COG2409	Drug exporters of the RND superfamily
AB454_RS13355	COG0436	Aminotransferase
AB454_RS13385	COG3942	CHAP domain
AB454_RS13390	COG2755	lipolytic protein G-D-S-L family
AB454_RS13390	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB454_RS13500	COG3001	Fructosamine kinase
AB454_RS13505	COG0167	dihydroorotate dehydrogenase activity
AB454_RS13555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AB454_RS13560	COG3527	Alpha-acetolactate decarboxylase
AB454_RS13575	COG0531	amino acid
AB454_RS13605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB454_RS13625	COG1012	belongs to the aldehyde dehydrogenase family
AB454_RS13635	COG1510	regulation of RNA biosynthetic process
AB454_RS13645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB454_RS13670	COG2851	Citrate transporter
AB454_RS13680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AB454_RS13690	COG0386	Belongs to the glutathione peroxidase family
AB454_RS13715	COG1136	(ABC) transporter
AB454_RS13720	COG2205	protein histidine kinase activity
AB454_RS13725	COG0745	RESPONSE REGULATOR receiver
AB454_RS13735	COG1785	Belongs to the alkaline phosphatase family
AB454_RS13745	COG1846	Transcriptional regulator
AB454_RS13790	COG1438	arginine binding
AB454_RS13810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB454_RS13810	COG3711	transcriptional antiterminator
AB454_RS13815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB454_RS13815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB454_RS13815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB454_RS13820	COG1482	cell wall glycoprotein biosynthetic process
AB454_RS13830	COG3942	CHAP domain
AB454_RS13830	COG1705	Flagellar rod assembly protein muramidase FlgJ
AB454_RS13835	COG1535	isochorismatase
AB454_RS13835	COG3433	isochorismatase activity
AB454_RS13850	COG0438	transferase activity, transferring glycosyl groups
AB454_RS13865	COG1073	alpha beta
AB454_RS13885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB454_RS13905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB454_RS13960	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AB454_RS13995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB454_RS14075	COG0471	metal ion transport
AB454_RS14080	COG2962	Rard protein
AB454_RS14090	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AB454_RS14105	COG1136	(ABC) transporter
AB454_RS14110	COG0577	efflux transmembrane transporter activity
AB454_RS14120	COG1278	Cold shock
AB454_RS14140	COG1475	DNA binding
AB454_RS14190	COG3682	Transcriptional regulator
AB454_RS14270	COG1136	(ABC) transporter
AB454_RS14270	COG0577	efflux transmembrane transporter activity