locus-tag	class	description
DU470_RS00015	COG2501	S4 domain
DU470_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DU470_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DU470_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DU470_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
DU470_RS00120	COG4863	YycH protein
DU470_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DU470_RS00135	COG0737	Belongs to the 5'-nucleotidase family
DU470_RS00230	COG2226	methyltransferase
DU470_RS00240	COG0823	Involved in the tonB-independent uptake of proteins
DU470_RS00270	COG1473	amidohydrolase
DU470_RS00285	COG1283	sodium-dependent phosphate transmembrane transporter activity
DU470_RS00290	COG4716	Myosin-crossreactive antigen
DU470_RS00295	COG0697	spore germination
DU470_RS00310	COG1620	l-lactate permease
DU470_RS00330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU470_RS00335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU470_RS00340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DU470_RS00350	COG2423	ornithine cyclodeaminase activity
DU470_RS00355	COG4264	IucA IucC family
DU470_RS00360	COG2814	Major facilitator Superfamily
DU470_RS00365	COG4264	IucA IucC family
DU470_RS00370	COG4264	IucA IucC family
DU470_RS00380	COG0019	diaminopimelate decarboxylase activity
DU470_RS00385	COG1475	DNA binding
DU470_RS00415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DU470_RS00420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DU470_RS00425	COG0438	transferase activity, transferring glycosyl groups
DU470_RS00460	COG0813	purine-nucleoside phosphorylase activity
DU470_RS00465	COG2814	Major facilitator Superfamily
DU470_RS00485	COG3639	organic phosphonate transmembrane transporter activity
DU470_RS00505	COG0737	Belongs to the 5'-nucleotidase family
DU470_RS00550	COG1454	alcohol dehydrogenase
DU470_RS00550	COG1012	belongs to the aldehyde dehydrogenase family
DU470_RS00575	COG1086	Polysaccharide biosynthesis protein
DU470_RS00585	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DU470_RS00615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DU470_RS00625	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DU470_RS00630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DU470_RS00640	COG2832	Protein of unknown function (DUF454)
DU470_RS00675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DU470_RS00680	COG1960	acyl-CoA dehydrogenase activity
DU470_RS00685	COG5609	conserved protein (DUF2294)
DU470_RS00735	COG1114	Component of the transport system for branched-chain amino acids
DU470_RS00740	COG1335	isochorismatase
DU470_RS00745	COG3961	Belongs to the TPP enzyme family
DU470_RS00775	COG1737	Transcriptional regulator
DU470_RS00810	COG0601	transmembrane transport
DU470_RS00815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DU470_RS00825	COG0405	Gamma-glutamyltransferase
DU470_RS00845	COG3842	ATPase activity
DU470_RS00855	COG1175	transmembrane transport
DU470_RS00860	COG3833	ABC-type maltose transport systems, permease component
DU470_RS00865	COG0673	inositol 2-dehydrogenase activity
DU470_RS00870	COG0673	inositol 2-dehydrogenase activity
DU470_RS00880	COG1755	Isoprenylcysteine carboxyl methyltransferase
DU470_RS00940	COG0183	Belongs to the thiolase family
DU470_RS00950	COG1960	acyl-CoA dehydrogenase activity
DU470_RS00955	COG0318	PFAM AMP-dependent synthetase and ligase
DU470_RS00970	COG0747	negative chemotaxis
DU470_RS00975	COG3189	MarR family transcriptional regulator
DU470_RS01005	COG1263	PTS System
DU470_RS01005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DU470_RS01005	COG2190	(PTS) system
DU470_RS01010	COG1957	nucleoside hydrolase
DU470_RS01030	COG3414	Phosphotransferase system galactitol-specific IIB component
DU470_RS01035	COG3775	system Galactitol-specific IIC component
DU470_RS01040	COG1063	alcohol dehydrogenase
DU470_RS01050	COG1063	alcohol dehydrogenase
DU470_RS01060	COG1063	alcohol dehydrogenase
DU470_RS01065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DU470_RS01085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DU470_RS01095	COG1063	alcohol dehydrogenase
DU470_RS01100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DU470_RS01135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DU470_RS01145	COG1263	PTS System
DU470_RS01145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DU470_RS01145	COG2190	(PTS) system
DU470_RS01150	COG2723	6-phospho-beta-galactosidase activity
DU470_RS01155	COG2226	methyltransferase
DU470_RS01210	COG1131	(ABC) transporter
DU470_RS01245	COG1388	LysM domain
DU470_RS01245	COG3942	CHAP domain
DU470_RS01415	COG1114	Component of the transport system for branched-chain amino acids
DU470_RS01425	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DU470_RS01435	COG0577	efflux transmembrane transporter activity
DU470_RS01465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DU470_RS01470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DU470_RS01495	COG3314	Sporulation integral membrane protein YlbJ
DU470_RS01520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DU470_RS01560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DU470_RS01565	COG3711	transcriptional antiterminator
DU470_RS01590	COG2271	Major facilitator Superfamily
DU470_RS01595	COG0346	lactoylglutathione lyase activity
DU470_RS01600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DU470_RS01605	COG0431	NADPH-dependent FMN reductase
DU470_RS01620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DU470_RS01625	COG2822	iron ion transport
DU470_RS01635	COG0672	)-iron permease
DU470_RS01640	COG0805	protein transport
DU470_RS01645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DU470_RS01655	COG1476	TRANSCRIPTIONal
DU470_RS01665	COG1131	(ABC) transporter
DU470_RS01695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DU470_RS01695	COG0646	methionine synthase
DU470_RS01700	COG0626	cystathionine gamma-synthase activity
DU470_RS01705	COG0626	cystathionine gamma-synthase activity
DU470_RS01715	COG1475	DNA binding
DU470_RS01720	COG0668	transmembrane transport
DU470_RS01725	COG4481	Protein conserved in bacteria
DU470_RS01730	COG0012	GTP binding
DU470_RS01835	COG1823	symporter activity
DU470_RS01870	COG2233	PERMEase
DU470_RS01960	COG3759	membrane
DU470_RS02110	COG0523	cobalamin synthesis protein
DU470_RS02135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DU470_RS02145	COG5609	conserved protein (DUF2294)
DU470_RS02160	COG1647	Serine aminopeptidase, S33
DU470_RS02170	COG0733	neurotransmitter:sodium symporter activity
DU470_RS02175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DU470_RS02180	COG0626	cystathionine gamma-synthase activity
DU470_RS02190	COG2011	ABC-type metal ion transport system permease component
DU470_RS02195	COG1464	Belongs to the NlpA lipoprotein family
DU470_RS02230	COG0583	DNA-binding transcription factor activity
DU470_RS02235	COG0070	glutamate synthase
DU470_RS02235	COG0069	glutamate synthase activity
DU470_RS02235	COG0067	glutamate synthase
DU470_RS02240	COG0493	'glutamate synthase
DU470_RS02250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DU470_RS02250	COG1263	PTS System
DU470_RS02255	COG0366	Alpha amylase catalytic
DU470_RS02260	COG2188	Transcriptional regulator
DU470_RS02280	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DU470_RS02320	COG1982	Orn Lys Arg decarboxylase major
DU470_RS02330	COG3870	Protein conserved in bacteria
DU470_RS02335	COG0470	DNA polymerase III
DU470_RS02340	COG1774	PSP1 C-terminal conserved region
DU470_RS02350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DU470_RS02360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DU470_RS02370	COG0084	hydrolase, TatD family'
DU470_RS02375	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DU470_RS02385	COG4466	Protein conserved in bacteria
DU470_RS02395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DU470_RS02400	COG0251	oxidation-reduction process
DU470_RS02445	COG2244	polysaccharide biosynthetic process
DU470_RS02450	COG3956	TIGRFAM MazG family protein
DU470_RS02455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DU470_RS02465	COG1098	S1 RNA binding domain
DU470_RS02480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DU470_RS02505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DU470_RS02600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DU470_RS02615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DU470_RS02625	COG3880	PFAM UvrB UvrC protein
DU470_RS02640	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DU470_RS02645	COG4956	integral membrane protein (PIN domain superfamily)
DU470_RS02670	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DU470_RS02730	COG2813	Specifically methylates the guanine in position
DU470_RS02805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DU470_RS02810	COG1428	Deoxynucleoside kinase
DU470_RS02815	COG1428	Deoxynucleoside kinase
DU470_RS02825	COG0561	phosphatase activity
DU470_RS02870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DU470_RS02985	COG0095	Lipoate-protein ligase
DU470_RS03000	COG0083	homoserine kinase activity
DU470_RS03020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DU470_RS03055	COG0667	Aldo Keto reductase
DU470_RS03065	COG0655	NAD(P)H dehydrogenase (quinone) activity
DU470_RS03075	COG1078	dGTPase activity
DU470_RS03110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DU470_RS03115	COG4139	cobalamin transport
DU470_RS03165	COG4974	Belongs to the 'phage' integrase family
DU470_RS03210	COG0803	Belongs to the bacterial solute-binding protein 9 family
DU470_RS03215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DU470_RS03220	COG1121	(ABC) transporter
DU470_RS03225	COG1321	iron dependent repressor
DU470_RS03235	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DU470_RS03245	COG1682	transport, permease protein
DU470_RS03250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DU470_RS03260	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DU470_RS03265	COG1686	Belongs to the peptidase S11 family
DU470_RS03270	COG1132	(ABC) transporter
DU470_RS03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DU470_RS03285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DU470_RS03290	COG1120	ATPase activity
DU470_RS03295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU470_RS03300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU470_RS03305	COG2376	Dihydroxyacetone kinase
DU470_RS03315	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DU470_RS03325	COG3949	Membrane
DU470_RS03350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DU470_RS03365	COG1136	(ABC) transporter
DU470_RS03370	COG0577	efflux transmembrane transporter activity
DU470_RS03375	COG1392	Phosphate transport regulator
DU470_RS03380	COG0306	phosphate transporter
DU470_RS03385	COG3942	CHAP domain
DU470_RS03385	COG1388	LysM domain
DU470_RS03395	COG1917	Cupin 2, conserved barrel domain protein
DU470_RS03395	COG4977	sequence-specific DNA binding
DU470_RS03425	COG0583	DNA-binding transcription factor activity
DU470_RS03435	COG2814	Major facilitator Superfamily
DU470_RS03440	COG2839	Protein conserved in bacteria
DU470_RS03470	COG1611	Belongs to the LOG family
DU470_RS03490	COG4988	ABC transporter
DU470_RS03495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DU470_RS03505	COG0523	cobalamin synthesis protein
DU470_RS03510	COG4989	oxidoreductase activity
DU470_RS03520	COG0471	metal ion transport
DU470_RS03525	COG0415	Belongs to the DNA photolyase family
DU470_RS03555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DU470_RS03560	COG1349	DNA-binding transcription factor activity
DU470_RS03565	COG1105	Belongs to the carbohydrate kinase PfkB family
DU470_RS03570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DU470_RS03570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DU470_RS03570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DU470_RS03575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DU470_RS03580	COG1253	flavin adenine dinucleotide binding
DU470_RS03585	COG0656	L-ascorbic acid biosynthetic process
DU470_RS03590	COG0463	Glycosyl transferase, family 2
DU470_RS03625	COG0720	synthase
DU470_RS03635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DU470_RS03635	COG0512	Glutamine amidotransferase of anthranilate synthase
DU470_RS03640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DU470_RS03670	COG0488	(ABC) transporter
DU470_RS03675	COG0514	ATP-dependent DNA helicase (RecQ)
DU470_RS03685	COG1174	glycine betaine transport
DU470_RS03715	COG3104	oligopeptide transport
DU470_RS03745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DU470_RS03750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DU470_RS03765	COG4605	iron ion homeostasis
DU470_RS03770	COG4604	ABC transporter, ATP-binding protein
DU470_RS03775	COG4607	ABC-type enterochelin transport system periplasmic component
DU470_RS03830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DU470_RS03835	COG1739	Uncharacterized protein family UPF0029
DU470_RS03845	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DU470_RS03850	COG1040	competence protein
DU470_RS03880	COG1388	LysM domain
DU470_RS03880	COG3942	CHAP domain
DU470_RS03945	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DU470_RS04010	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DU470_RS04015	COG1647	Serine aminopeptidase, S33
DU470_RS04080	COG1278	Cold shock
DU470_RS04120	COG0406	alpha-ribazole phosphatase activity
DU470_RS04125	COG1279	arginine transmembrane transporter activity
DU470_RS04150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DU470_RS04155	COG1393	Belongs to the ArsC family
DU470_RS04170	COG3878	Protein conserved in bacteria
DU470_RS04180	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DU470_RS04195	COG2011	ABC-type metal ion transport system permease component
DU470_RS04200	COG1464	Belongs to the NlpA lipoprotein family
DU470_RS04215	COG0396	ATPase activity
DU470_RS04220	COG0719	Fe-S assembly protein
DU470_RS04230	COG0822	iron-sulfur transferase activity
DU470_RS04310	COG0629	single-stranded DNA binding
DU470_RS04330	COG1484	DNA-dependent DNA replication
DU470_RS04420	COG1783	phage Terminase large subunit
DU470_RS04550	COG1388	LysM domain
DU470_RS04550	COG5632	N-Acetylmuramoyl-L-alanine amidase
DU470_RS04585	COG1253	flavin adenine dinucleotide binding
DU470_RS04595	COG1801	Protein of unknown function DUF72
DU470_RS04600	COG0730	response to heat
DU470_RS04615	COG4470	Protein conserved in bacteria
DU470_RS04625	COG2445	Protein of unknown function DUF86
DU470_RS04655	COG1696	Membrane protein involved in D-alanine export
DU470_RS04665	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DU470_RS04670	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DU470_RS04675	COG4837	Protein of unknown function (DUF1462)
DU470_RS04680	COG1252	NADH dehydrogenase
DU470_RS04690	COG0316	Belongs to the HesB IscA family
DU470_RS04700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DU470_RS04705	COG2056	Na+-H+ antiporter family
DU470_RS04710	COG2050	protein possibly involved in aromatic compounds catabolism
DU470_RS04765	COG1098	S1 RNA binding domain
DU470_RS04770	COG1902	pentaerythritol trinitrate reductase activity
DU470_RS04785	COG0584	glycerophosphoryl diester phosphodiesterase
DU470_RS04805	COG0398	Pfam SNARE associated Golgi protein
DU470_RS04855	COG0561	phosphatase activity
DU470_RS04895	COG1881	PFAM PEBP family protein
DU470_RS04925	COG0601	transmembrane transport
DU470_RS04930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DU470_RS04935	COG0444	Belongs to the ABC transporter superfamily
DU470_RS04940	COG4608	Belongs to the ABC transporter superfamily
DU470_RS04945	COG4166	transmembrane transport
DU470_RS04950	COG0747	negative chemotaxis
DU470_RS04955	COG0444	Belongs to the ABC transporter superfamily
DU470_RS04960	COG4608	Belongs to the ABC transporter superfamily
DU470_RS04965	COG0601	transmembrane transport
DU470_RS04970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DU470_RS04995	COG1164	Oligoendopeptidase f
DU470_RS05005	COG2346	COG2346, Truncated hemoglobins
DU470_RS05020	COG2357	RelA SpoT domain protein
DU470_RS05030	COG0564	pseudouridine synthase activity
DU470_RS05035	COG2239	Acts as a magnesium transporter
DU470_RS05040	COG0569	domain protein
DU470_RS05040	COG0475	glutathione-regulated potassium exporter activity
DU470_RS05050	COG0628	permease
DU470_RS05055	COG1115	amino acid carrier protein
DU470_RS05105	COG0861	Integral membrane protein TerC family
DU470_RS05115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DU470_RS05120	COG0737	Belongs to the 5'-nucleotidase family
DU470_RS05135	COG4903	ComK protein
DU470_RS05150	COG4873	Protein conserved in bacteria
DU470_RS05205	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DU470_RS05215	COG2314	TM2 domain
DU470_RS05220	COG0456	acetyltransferase
DU470_RS05225	COG1575	Belongs to the MenA family. Type 1 subfamily
DU470_RS05235	COG1169	isochorismate synthase
DU470_RS05245	COG2267	carboxylic ester hydrolase activity
DU470_RS05270	COG0436	Aminotransferase
DU470_RS05275	COG3594	Acyltransferase
DU470_RS05305	COG1316	TRANSCRIPTIONal
DU470_RS05350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DU470_RS05365	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DU470_RS05405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DU470_RS05410	COG4172	Belongs to the ABC transporter superfamily
DU470_RS05415	COG4721	ABC-type cobalt transport system, permease component
DU470_RS05440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DU470_RS05465	COG1271	oxidase subunit
DU470_RS05470	COG1294	oxidase, subunit
DU470_RS05475	COG0569	domain protein
DU470_RS05540	COG1176	ABC-type spermidine putrescine transport system, permease component I
DU470_RS05545	COG1177	transmembrane transport
DU470_RS05550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DU470_RS05575	COG0483	inositol monophosphate 1-phosphatase activity
DU470_RS05585	COG1217	gtp-binding protein TYPA
DU470_RS05595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DU470_RS05605	COG0772	Belongs to the SEDS family
DU470_RS05640	COG3679	Belongs to the UPF0342 family
DU470_RS05660	COG0742	ribosomal rna small subunit methyltransferase
DU470_RS05720	COG4509	Sortase family
DU470_RS05735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DU470_RS05770	COG1796	DNA polymerase
DU470_RS05770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DU470_RS05795	COG2009	succinate dehydrogenase
DU470_RS05800	COG1053	succinate dehydrogenase
DU470_RS05805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DU470_RS05925	COG1288	antiporter activity
DU470_RS05965	COG1011	Hydrolase
DU470_RS05990	COG4839	cell division protein FtsL
DU470_RS05995	COG0768	penicillin binding
DU470_RS06010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DU470_RS06015	COG0849	cell division
DU470_RS06030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DU470_RS06040	COG0762	integral membrane protein
DU470_RS06045	COG2302	S4 RNA-binding domain
DU470_RS06060	COG2514	catechol 2,3-dioxygenase activity
DU470_RS06080	COG0564	pseudouridine synthase activity
DU470_RS06090	COG2233	PERMEase
DU470_RS06135	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DU470_RS06150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DU470_RS06155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DU470_RS06180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DU470_RS06180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DU470_RS06190	COG0631	protein serine/threonine phosphatase activity
DU470_RS06205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DU470_RS06220	COG1302	Protein conserved in bacteria
DU470_RS06270	COG1196	nuclear chromosome segregation
DU470_RS06275	COG0552	protein localization to endoplasmic reticulum
DU470_RS06285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DU470_RS06340	COG2348	transferase activity, transferring amino-acyl groups
DU470_RS06345	COG0758	DNA mediated transformation
DU470_RS06445	COG0195	Participates in both transcription termination and antitermination
DU470_RS06450	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DU470_RS06475	COG0196	riboflavin kinase activity
DU470_RS06505	COG2188	Transcriptional regulator
DU470_RS06510	COG0612	Peptidase, M16
DU470_RS06515	COG0612	Peptidase, M16
DU470_RS06520	COG0300	oxidoreductase activity
DU470_RS06540	COG1546	Belongs to the CinA family
DU470_RS06540	COG1058	Belongs to the CinA family
DU470_RS06560	COG1692	metallophosphoesterase
DU470_RS06565	COG0674	pyruvate-flavodoxin oxidoreductase activity
DU470_RS06565	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DU470_RS06570	COG1013	pyruvate-flavodoxin oxidoreductase activity
DU470_RS06605	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DU470_RS06610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DU470_RS06635	COG1923	regulation of RNA biosynthetic process
DU470_RS06645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DU470_RS06650	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DU470_RS06655	COG0789	Transcriptional regulator
DU470_RS06760	COG1131	(ABC) transporter
DU470_RS06775	COG2197	response regulator
DU470_RS06785	COG1525	nuclease
DU470_RS06800	COG0527	aspartate kinase activity
DU470_RS06805	COG0460	homoserine dehydrogenase
DU470_RS06810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DU470_RS06835	COG0833	amino acid
DU470_RS06865	COG2340	Cysteine-rich secretory protein family
DU470_RS06900	COG4846	Membrane protein involved in cytochrome C biogenesis
DU470_RS06920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DU470_RS06935	COG0824	Thioesterase
DU470_RS06965	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DU470_RS06975	COG1115	amino acid carrier protein
DU470_RS06990	COG0628	permease
DU470_RS07015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DU470_RS07025	COG1363	Peptidase, m42
DU470_RS07030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DU470_RS07035	COG0512	Glutamine amidotransferase of anthranilate synthase
DU470_RS07075	COG0561	phosphatase activity
DU470_RS07120	COG0704	Plays a role in the regulation of phosphate uptake
DU470_RS07130	COG0581	inorganic phosphate transmembrane transporter activity
DU470_RS07135	COG0573	inorganic phosphate transmembrane transporter activity
DU470_RS07150	COG0488	(ABC) transporter
DU470_RS07155	COG0527	aspartate kinase activity
DU470_RS07160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DU470_RS07250	COG4548	von Willebrand factor, type A
DU470_RS07255	COG0714	Associated with various cellular activities
DU470_RS07300	COG0671	phosphoesterase, PA-phosphatase related
DU470_RS07365	COG1413	lyase activity
DU470_RS07375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DU470_RS07395	COG0531	amino acid
DU470_RS07410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DU470_RS07415	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DU470_RS07430	COG0116	Belongs to the methyltransferase superfamily
DU470_RS07465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DU470_RS07465	COG4499	WXG100 protein secretion system (Wss), protein YukC
DU470_RS07475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DU470_RS07480	COG3935	DnaD domain protein
DU470_RS07505	COG0438	transferase activity, transferring glycosyl groups
DU470_RS07510	COG1694	Mazg nucleotide pyrophosphohydrolase
DU470_RS07515	COG2738	Putative neutral zinc metallopeptidase
DU470_RS07520	COG4347	Protein of unknown function (DUF1405)
DU470_RS07560	COG0142	geranyltranstransferase activity
DU470_RS07625	COG0492	ferredoxin-NADP+ reductase activity
DU470_RS07640	COG0514	ATP-dependent DNA helicase (RecQ)
DU470_RS07650	COG1141	Ferredoxin
DU470_RS07685	COG5002	protein histidine kinase activity
DU470_RS07690	COG0745	RESPONSE REGULATOR receiver
DU470_RS07695	COG1187	pseudouridine synthase activity
DU470_RS07720	COG0735	belongs to the Fur family
DU470_RS07725	COG0494	nUDIX hydrolase
DU470_RS07730	COG0667	Aldo Keto reductase
DU470_RS07740	COG4221	oxidoreductase activity
DU470_RS07755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DU470_RS07765	COG0366	Alpha amylase catalytic
DU470_RS07770	COG1609	Transcriptional regulator
DU470_RS07790	COG2195	Cleaves the N-terminal amino acid of tripeptides
DU470_RS07800	COG4129	membrane
DU470_RS07810	COG0508	dehydrogenase complex catalyzes the overall conversion of
DU470_RS07815	COG0022	dehydrogenase e1 component
DU470_RS07820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DU470_RS07825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DU470_RS07830	COG0497	DNA recombination
DU470_RS07860	COG1302	Protein conserved in bacteria
DU470_RS07865	COG0439	Biotin carboxylase
DU470_RS07870	COG0511	ligase activity, forming carbon-carbon bonds
DU470_RS07880	COG0006	proline dipeptidase activity
DU470_RS07895	COG0095	Lipoate-protein ligase
DU470_RS07900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DU470_RS07945	COG4537	Required for transformation and DNA binding
DU470_RS07950	COG1459	type II secretion system
DU470_RS07955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DU470_RS07960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DU470_RS07965	COG0011	TIGRFAM Protein of
DU470_RS07970	COG1940	carbohydrate kinase activity
DU470_RS07975	COG4483	Protein conserved in bacteria
DU470_RS07985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DU470_RS07995	COG0768	penicillin binding
DU470_RS08010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DU470_RS08015	COG1121	(ABC) transporter
DU470_RS08025	COG0513	Belongs to the DEAD box helicase family
DU470_RS08035	COG2384	SAM-dependent methyltransferase
DU470_RS08075	COG0295	cytidine deaminase activity
DU470_RS08090	COG1702	phosphate starvation-inducible protein PhoH
DU470_RS08105	COG1030	water channel activity
DU470_RS08115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DU470_RS08120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DU470_RS08150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DU470_RS08170	COG1466	dna polymerase III delta subunit
DU470_RS08180	COG2131	deaminase
DU470_RS08190	COG2226	methyltransferase
DU470_RS08195	COG0799	negative regulation of ribosome biogenesis
DU470_RS08200	COG1713	HD superfamily hydrolase involved in NAD metabolism
DU470_RS08210	COG1534	Rna-binding protein
DU470_RS08220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DU470_RS08225	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DU470_RS08250	COG1914	H( )-stimulated, divalent metal cation uptake system
DU470_RS08260	COG0439	Biotin carboxylase
DU470_RS08265	COG0511	ligase activity, forming carbon-carbon bonds
DU470_RS08270	COG1984	allophanate hydrolase subunit 2
DU470_RS08275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DU470_RS08290	COG0826	peptidase U32
DU470_RS08295	COG0826	peptidase U32
DU470_RS08325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DU470_RS08350	COG1104	cysteine desulfurase activity
DU470_RS08355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DU470_RS08365	COG3237	CsbD-like
DU470_RS08370	COG1959	2 iron, 2 sulfur cluster binding
DU470_RS08375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DU470_RS08380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DU470_RS08425	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DU470_RS08425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DU470_RS08430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DU470_RS08430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DU470_RS08435	COG1862	Preprotein translocase
DU470_RS08475	COG2868	ribosomal protein
DU470_RS08520	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DU470_RS08530	COG0285	dihydrofolate synthase activity
DU470_RS08540	COG2818	Glycosylase
DU470_RS08575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DU470_RS08610	COG4112	unkown
DU470_RS08635	COG0833	amino acid
DU470_RS08650	COG1484	DNA-dependent DNA replication
DU470_RS08680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DU470_RS08680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DU470_RS08690	COG5002	protein histidine kinase activity
DU470_RS08695	COG0745	RESPONSE REGULATOR receiver
DU470_RS08710	COG0372	Belongs to the citrate synthase family
DU470_RS08715	COG1113	amino acid transport
DU470_RS08740	COG0281	malic enzyme
DU470_RS08750	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DU470_RS08760	COG4109	DRTGG domain
DU470_RS08800	COG0827	DNA restriction-modification system
DU470_RS08810	COG0730	response to heat
DU470_RS08820	COG1104	cysteine desulfurase activity
DU470_RS08830	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DU470_RS08835	COG1956	GAF domain-containing protein
DU470_RS08855	COG0584	glycerophosphoryl diester phosphodiesterase
DU470_RS08860	COG1764	response to oxidative stress
DU470_RS08865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DU470_RS08870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DU470_RS08885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DU470_RS08885	COG1263	PTS System
DU470_RS08890	COG0204	Acyl-transferase
DU470_RS08895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DU470_RS08925	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DU470_RS08930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DU470_RS08935	COG0454	-acetyltransferase
DU470_RS08955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DU470_RS08955	COG1605	Chorismate mutase
DU470_RS08980	COG1674	ftsk spoiiie
DU470_RS08985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DU470_RS08995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DU470_RS09000	COG1363	Peptidase, m42
DU470_RS09010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DU470_RS09020	COG0510	thiamine kinase activity
DU470_RS09040	COG1187	pseudouridine synthase activity
DU470_RS09045	COG2244	polysaccharide biosynthetic process
DU470_RS09050	COG2081	HI0933 family
DU470_RS09070	COG2814	Major facilitator Superfamily
DU470_RS09080	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DU470_RS09095	COG2267	carboxylic ester hydrolase activity
DU470_RS09130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DU470_RS09130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DU470_RS09150	COG4193	domain, Protein
DU470_RS09150	COG5632	N-Acetylmuramoyl-L-alanine amidase
DU470_RS09150	COG3266	domain, Protein
DU470_RS09180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DU470_RS09205	COG0656	L-ascorbic acid biosynthetic process
DU470_RS09225	COG1506	peptidase
DU470_RS09470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DU470_RS09500	COG1131	(ABC) transporter
DU470_RS09505	COG0537	adenosine 5'-monophosphoramidase activity
DU470_RS09540	COG0420	3'-5' exonuclease activity
DU470_RS09570	COG2197	response regulator
DU470_RS09575	COG4585	Histidine kinase
DU470_RS09575	COG2203	Gaf domain
DU470_RS09580	COG0564	pseudouridine synthase activity
DU470_RS09620	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DU470_RS09625	COG1126	abc transporter atp-binding protein
DU470_RS09630	COG0765	amino acid transport
DU470_RS09795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DU470_RS09800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DU470_RS09810	COG4129	membrane
DU470_RS09835	COG1988	membrane-bound metal-dependent
DU470_RS09850	COG1388	LysM domain
DU470_RS09850	COG1134	teichoic acid transport
DU470_RS09880	COG0535	radical SAM domain protein
DU470_RS09885	COG1607	acyl-coa hydrolase
DU470_RS09890	COG2309	aminopeptidase activity
DU470_RS09910	COG1295	ribonuclease BN
DU470_RS09915	COG2197	response regulator
DU470_RS10040	COG4851	CamS sex pheromone cAM373 precursor
DU470_RS10050	COG0210	DNA helicase
DU470_RS10060	COG4496	protein, YerC YecD
DU470_RS10095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DU470_RS10105	COG0077	Prephenate dehydratase
DU470_RS10125	COG1335	isochorismatase
DU470_RS10140	COG1012	belongs to the aldehyde dehydrogenase family
DU470_RS10195	COG4974	Belongs to the 'phage' integrase family
DU470_RS10245	COG1131	(ABC) transporter
DU470_RS10260	COG1725	Transcriptional regulator
DU470_RS10320	COG0860	N-Acetylmuramoyl-L-alanine amidase
DU470_RS10320	COG1388	LysM domain
DU470_RS10335	COG1388	LysM domain
DU470_RS10335	COG5632	N-Acetylmuramoyl-L-alanine amidase
DU470_RS10380	COG0739	heme binding
DU470_RS10430	COG0740	serine-type endopeptidase activity
DU470_RS10600	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DU470_RS10650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DU470_RS10655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DU470_RS10660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DU470_RS10735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DU470_RS10740	COG1621	beta-fructofuranosidase activity
DU470_RS10745	COG1609	Transcriptional regulator
DU470_RS10750	COG0004	ammonium transporteR
DU470_RS10755	COG0425	Belongs to the sulfur carrier protein TusA family
DU470_RS10760	COG2391	methyltransferase activity
DU470_RS10770	COG0488	(ABC) transporter
DU470_RS10780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DU470_RS10790	COG0456	acetyltransferase
DU470_RS10795	COG1214	PFAM Peptidase M22, glycoprotease
DU470_RS10800	COG0802	atpase or kinase
DU470_RS10815	COG0028	Belongs to the TPP enzyme family
DU470_RS10895	COG2183	response to ionizing radiation
DU470_RS10900	COG1191	sigma factor activity
DU470_RS10910	COG1366	Belongs to the anti-sigma-factor antagonist family
DU470_RS10915	COG2208	phosphoserine phosphatase activity
DU470_RS10950	COG3428	Bacterial PH domain
DU470_RS10980	COG2205	protein histidine kinase activity
DU470_RS10985	COG0745	RESPONSE REGULATOR receiver
DU470_RS10995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DU470_RS11005	COG0772	Belongs to the SEDS family
DU470_RS11020	COG1937	Protein conserved in bacteria
DU470_RS11030	COG1418	mRNA catabolic process
DU470_RS11070	COG0629	single-stranded DNA binding
DU470_RS11145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DU470_RS11170	COG0009	L-threonylcarbamoyladenylate synthase
DU470_RS11175	COG2890	protein-(glutamine-N5) methyltransferase activity
DU470_RS11200	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DU470_RS11250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DU470_RS11300	COG0813	purine-nucleoside phosphorylase activity
DU470_RS11305	COG0783	Belongs to the Dps family
DU470_RS11325	COG1482	cell wall glycoprotein biosynthetic process
DU470_RS11330	COG0702	epimerase
DU470_RS11335	COG0640	Transcriptional regulator
DU470_RS11370	COG0561	phosphatase activity
DU470_RS11375	COG1119	ATPase activity
DU470_RS11390	COG3711	transcriptional antiterminator
DU470_RS11420	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DU470_RS11480	COG0489	protein tyrosine kinase activity
DU470_RS11485	COG2814	Major facilitator Superfamily
DU470_RS11500	COG1272	protein, Hemolysin III
DU470_RS11510	COG1988	membrane-bound metal-dependent
DU470_RS11520	COG3314	Sporulation integral membrane protein YlbJ
DU470_RS11525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU470_RS11530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU470_RS11535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU470_RS11540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DU470_RS11550	COG3457	Alanine racemase
DU470_RS11555	COG4264	IucA IucC family
DU470_RS11560	COG2814	Major facilitator Superfamily
DU470_RS11585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DU470_RS11595	COG2130	NADP-dependent
DU470_RS11665	COG0656	L-ascorbic acid biosynthetic process
DU470_RS11670	COG0789	Transcriptional regulator
DU470_RS11680	COG5492	domain, Protein
DU470_RS11690	COG3527	Alpha-acetolactate decarboxylase
DU470_RS11695	COG0028	Belongs to the TPP enzyme family
DU470_RS11785	COG0201	protein transport
DU470_RS11900	COG2252	PERMEase
DU470_RS11950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DU470_RS12020	COG1763	Mo-molybdopterin cofactor biosynthetic process
DU470_RS12040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DU470_RS12045	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DU470_RS12050	COG4149	molybdate abc transporter
DU470_RS12055	COG0725	ABC transporter, periplasmic molybdate-binding protein
DU470_RS12070	COG1268	BioY protein
DU470_RS12085	COG1960	acyl-CoA dehydrogenase activity
DU470_RS12090	COG4413	Urea transporter
DU470_RS12165	COG1757	Na H antiporter
DU470_RS12180	COG3942	CHAP domain
DU470_RS12255	COG1113	amino acid transport
DU470_RS12275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DU470_RS12280	COG0385	Bile acid
DU470_RS12290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DU470_RS12290	COG1263	PTS System
DU470_RS12295	COG1737	Transcriptional regulator
DU470_RS12315	COG1028	Short-chain dehydrogenase reductase Sdr
DU470_RS12320	COG1473	amidohydrolase
DU470_RS12335	COG0583	DNA-binding transcription factor activity
DU470_RS12360	COG2258	MOSC domain
DU470_RS12380	COG1668	transmembrane transport
DU470_RS12385	COG4152	abc transporter atp-binding protein
DU470_RS12390	COG3152	Membrane
DU470_RS12410	COG0786	glutamate:sodium symporter activity
DU470_RS12420	COG0598	Magnesium transport protein CorA
DU470_RS12435	COG0657	acetylesterase activity
DU470_RS12445	COG2814	Major facilitator Superfamily
DU470_RS12450	COG1566	PFAM secretion protein HlyD family protein
DU470_RS12460	COG2814	Major facilitator Superfamily
DU470_RS12525	COG1620	l-lactate permease
DU470_RS12545	COG0604	alcohol dehydrogenase
DU470_RS12555	COG0456	acetyltransferase
DU470_RS12580	COG1511	domain protein
DU470_RS12595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DU470_RS12595	COG1263	PTS System
DU470_RS12610	COG3871	stress protein (general stress protein 26)
DU470_RS12660	COG2181	nitrate reductase activity
DU470_RS12670	COG1140	nitrate reductase beta subunit
DU470_RS12675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DU470_RS12685	COG2146	nitrite reductase [NAD(P)H] activity
DU470_RS12690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DU470_RS12700	COG0454	-acetyltransferase
DU470_RS12705	COG2116	formate transmembrane transporter activity
DU470_RS12720	COG3443	Belongs to the bacterial solute-binding protein 9 family
DU470_RS12720	COG0803	Belongs to the bacterial solute-binding protein 9 family
DU470_RS12755	COG1126	abc transporter atp-binding protein
DU470_RS12760	COG0765	amino acid transport
DU470_RS12765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DU470_RS12770	COG2814	Major facilitator Superfamily
DU470_RS12790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DU470_RS12840	COG0156	8-amino-7-oxononanoate synthase activity
DU470_RS12850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DU470_RS12855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DU470_RS12870	COG1132	(ABC) transporter
DU470_RS12875	COG1132	(ABC) transporter
DU470_RS12875	COG2375	cellular response to nickel ion
DU470_RS12895	COG1929	Belongs to the glycerate kinase type-1 family
DU470_RS12905	COG2814	Major facilitator Superfamily
DU470_RS12925	COG1113	amino acid transport
DU470_RS12940	COG0531	amino acid
DU470_RS12965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DU470_RS12975	COG1174	glycine betaine transport
DU470_RS13005	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DU470_RS13015	COG0531	amino acid
DU470_RS13020	COG2272	Belongs to the type-B carboxylesterase lipase family
DU470_RS13025	COG2814	Major facilitator Superfamily
DU470_RS13030	COG0390	transport system, permease component
DU470_RS13035	COG4619	ABC transporter
DU470_RS13040	COG1363	Peptidase, m42
DU470_RS13060	COG4808	Protein conserved in bacteria
DU470_RS13065	COG0069	glutamate synthase activity
DU470_RS13080	COG1124	(ABC) transporter
DU470_RS13125	COG1028	Short-chain dehydrogenase reductase Sdr
DU470_RS13135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DU470_RS13235	COG0494	nUDIX hydrolase
DU470_RS13275	COG1846	Transcriptional regulator
DU470_RS13310	COG1070	Carbohydrate kinase
DU470_RS13315	COG1802	Transcriptional regulator
DU470_RS13320	COG0789	Transcriptional regulator
DU470_RS13325	COG2357	RelA SpoT domain protein
DU470_RS13330	COG4876	unkown
DU470_RS13345	COG2271	Major facilitator Superfamily
DU470_RS13350	COG0586	Pfam SNARE associated Golgi protein
DU470_RS13365	COG1131	(ABC) transporter
DU470_RS13385	COG0400	carboxylic ester hydrolase activity
DU470_RS13390	COG0346	lactoylglutathione lyase activity
DU470_RS13395	COG1846	Transcriptional regulator
DU470_RS13405	COG2514	catechol 2,3-dioxygenase activity
DU470_RS13420	COG0561	phosphatase activity
DU470_RS13425	COG1131	(ABC) transporter
DU470_RS13435	COG3764	Sortase (surface protein transpeptidase)
DU470_RS13455	COG1760	l-serine dehydratase
DU470_RS13460	COG1760	l-serine dehydratase
DU470_RS13475	COG0697	spore germination
DU470_RS13480	COG0657	acetylesterase activity
DU470_RS13500	COG0028	Belongs to the TPP enzyme family
DU470_RS13515	COG0583	DNA-binding transcription factor activity
DU470_RS13525	COG3942	CHAP domain
DU470_RS13535	COG3425	synthase
DU470_RS13540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DU470_RS13565	COG2409	Drug exporters of the RND superfamily
DU470_RS13610	COG0436	Aminotransferase
DU470_RS13640	COG3942	CHAP domain
DU470_RS13645	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DU470_RS13645	COG2755	lipolytic protein G-D-S-L family
DU470_RS13715	COG0596	Alpha beta hydrolase
DU470_RS13755	COG3001	Fructosamine kinase
DU470_RS13760	COG0167	dihydroorotate dehydrogenase activity
DU470_RS13810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DU470_RS13815	COG3527	Alpha-acetolactate decarboxylase
DU470_RS13825	COG0531	amino acid
DU470_RS13855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DU470_RS13875	COG1012	belongs to the aldehyde dehydrogenase family
DU470_RS13885	COG1510	regulation of RNA biosynthetic process
DU470_RS13890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DU470_RS13915	COG2851	Citrate transporter
DU470_RS13930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DU470_RS13940	COG0386	Belongs to the glutathione peroxidase family
DU470_RS13965	COG1136	(ABC) transporter
DU470_RS13970	COG2205	protein histidine kinase activity
DU470_RS13975	COG0745	RESPONSE REGULATOR receiver
DU470_RS13985	COG1785	Belongs to the alkaline phosphatase family
DU470_RS13995	COG1846	Transcriptional regulator
DU470_RS14040	COG1438	arginine binding
DU470_RS14060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DU470_RS14060	COG3711	transcriptional antiterminator
DU470_RS14065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DU470_RS14065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DU470_RS14065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DU470_RS14070	COG1482	cell wall glycoprotein biosynthetic process
DU470_RS14080	COG3942	CHAP domain
DU470_RS14080	COG1705	Flagellar rod assembly protein muramidase FlgJ
DU470_RS14085	COG3433	isochorismatase activity
DU470_RS14085	COG1535	isochorismatase
DU470_RS14100	COG0438	transferase activity, transferring glycosyl groups
DU470_RS14115	COG1073	alpha beta
DU470_RS14135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DU470_RS14155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DU470_RS14210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DU470_RS14245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DU470_RS14320	COG0471	metal ion transport
DU470_RS14325	COG2962	Rard protein
DU470_RS14335	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DU470_RS14350	COG1136	(ABC) transporter
DU470_RS14355	COG0577	efflux transmembrane transporter activity
DU470_RS14365	COG1278	Cold shock
DU470_RS14385	COG1475	DNA binding