locus-tag	class	description
RK70_RS00035	COG0473	3-isopropylmalate dehydrogenase activity
RK70_RS00055	COG0028	Belongs to the TPP enzyme family
RK70_RS00070	COG0802	atpase or kinase
RK70_RS00075	COG1214	PFAM Peptidase M22, glycoprotease
RK70_RS00080	COG0456	acetyltransferase
RK70_RS00090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK70_RS00100	COG0488	(ABC) transporter
RK70_RS00110	COG2391	methyltransferase activity
RK70_RS00115	COG0425	Belongs to the sulfur carrier protein TusA family
RK70_RS00120	COG0004	ammonium transporteR
RK70_RS00125	COG1609	Transcriptional regulator
RK70_RS00130	COG1621	beta-fructofuranosidase activity
RK70_RS00135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK70_RS00210	COG3728	DNA packaging
RK70_RS00210	COG5484	DNA packaging
RK70_RS00230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK70_RS00235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK70_RS00240	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RK70_RS00290	COG1725	Transcriptional regulator
RK70_RS00305	COG1131	(ABC) transporter
RK70_RS00360	COG1012	belongs to the aldehyde dehydrogenase family
RK70_RS00375	COG1335	isochorismatase
RK70_RS00385	COG0471	metal ion transport
RK70_RS00395	COG0077	Prephenate dehydratase
RK70_RS00405	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RK70_RS00445	COG4496	protein, YerC YecD
RK70_RS00455	COG0210	DNA helicase
RK70_RS00465	COG4851	CamS sex pheromone cAM373 precursor
RK70_RS00595	COG2197	response regulator
RK70_RS00600	COG1295	ribonuclease BN
RK70_RS00620	COG2309	aminopeptidase activity
RK70_RS00625	COG1607	acyl-coa hydrolase
RK70_RS00630	COG0535	radical SAM domain protein
RK70_RS00660	COG1388	LysM domain
RK70_RS00660	COG1134	teichoic acid transport
RK70_RS00675	COG1988	membrane-bound metal-dependent
RK70_RS00700	COG4129	membrane
RK70_RS00710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RK70_RS00715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK70_RS00890	COG0765	amino acid transport
RK70_RS00895	COG1126	abc transporter atp-binding protein
RK70_RS00900	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RK70_RS00940	COG0564	pseudouridine synthase activity
RK70_RS00945	COG2203	Gaf domain
RK70_RS00945	COG4585	Histidine kinase
RK70_RS00950	COG2197	response regulator
RK70_RS00980	COG0420	3'-5' exonuclease activity
RK70_RS01015	COG0537	adenosine 5'-monophosphoramidase activity
RK70_RS01020	COG1131	(ABC) transporter
RK70_RS01170	COG1131	(ABC) transporter
RK70_RS01350	COG1506	peptidase
RK70_RS01375	COG0656	L-ascorbic acid biosynthetic process
RK70_RS01400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RK70_RS01420	COG1595	DNA-templated transcription, initiation
RK70_RS01430	COG3266	domain, Protein
RK70_RS01430	COG4193	domain, Protein
RK70_RS01430	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK70_RS01455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK70_RS01455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK70_RS01490	COG2267	carboxylic ester hydrolase activity
RK70_RS01505	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RK70_RS01510	COG1242	4 iron, 4 sulfur cluster binding
RK70_RS01515	COG2814	Major facilitator Superfamily
RK70_RS01535	COG2081	HI0933 family
RK70_RS01540	COG2244	polysaccharide biosynthetic process
RK70_RS01545	COG1187	pseudouridine synthase activity
RK70_RS01570	COG0510	thiamine kinase activity
RK70_RS01580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK70_RS01590	COG1363	Peptidase, m42
RK70_RS01595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK70_RS01605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RK70_RS01610	COG1674	ftsk spoiiie
RK70_RS01635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RK70_RS01635	COG1605	Chorismate mutase
RK70_RS01655	COG0454	-acetyltransferase
RK70_RS01660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK70_RS01665	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RK70_RS01675	COG5386	Cell surface protein
RK70_RS01695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK70_RS01700	COG0204	Acyl-transferase
RK70_RS01705	COG1263	PTS System
RK70_RS01705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK70_RS01720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK70_RS01725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RK70_RS01730	COG1764	response to oxidative stress
RK70_RS01735	COG0584	glycerophosphoryl diester phosphodiesterase
RK70_RS01755	COG1956	GAF domain-containing protein
RK70_RS01770	COG1104	cysteine desulfurase activity
RK70_RS01790	COG0827	DNA restriction-modification system
RK70_RS01830	COG4109	DRTGG domain
RK70_RS01840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RK70_RS01845	COG0587	DNA-directed DNA polymerase activity
RK70_RS01850	COG0281	malic enzyme
RK70_RS01880	COG1113	amino acid transport
RK70_RS01885	COG0372	Belongs to the citrate synthase family
RK70_RS01900	COG0745	RESPONSE REGULATOR receiver
RK70_RS01905	COG5002	protein histidine kinase activity
RK70_RS01915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK70_RS01915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK70_RS01945	COG1484	DNA-dependent DNA replication
RK70_RS01955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RK70_RS01960	COG0833	amino acid
RK70_RS01985	COG4112	unkown
RK70_RS02015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RK70_RS02020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK70_RS02055	COG2818	Glycosylase
RK70_RS02065	COG0285	dihydrofolate synthase activity
RK70_RS02075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RK70_RS02120	COG2868	ribosomal protein
RK70_RS02160	COG1862	Preprotein translocase
RK70_RS02165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK70_RS02165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK70_RS02170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RK70_RS02170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RK70_RS02200	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RK70_RS02215	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RK70_RS02220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RK70_RS02225	COG1959	2 iron, 2 sulfur cluster binding
RK70_RS02230	COG3237	CsbD-like
RK70_RS02240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK70_RS02245	COG1104	cysteine desulfurase activity
RK70_RS02260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RK70_RS02310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RK70_RS02315	COG1984	allophanate hydrolase subunit 2
RK70_RS02320	COG0511	ligase activity, forming carbon-carbon bonds
RK70_RS02325	COG0439	Biotin carboxylase
RK70_RS02335	COG1914	H( )-stimulated, divalent metal cation uptake system
RK70_RS02340	COG3177	Filamentation induced by cAMP protein fic
RK70_RS02360	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RK70_RS02365	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RK70_RS02375	COG1534	Rna-binding protein
RK70_RS02385	COG1713	HD superfamily hydrolase involved in NAD metabolism
RK70_RS02390	COG0799	negative regulation of ribosome biogenesis
RK70_RS02395	COG2226	methyltransferase
RK70_RS02405	COG2131	deaminase
RK70_RS02410	COG2333	competence protein COMEC
RK70_RS02410	COG0658	competence protein
RK70_RS02415	COG1466	dna polymerase III delta subunit
RK70_RS02435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RK70_RS02465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RK70_RS02470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RK70_RS02480	COG1030	water channel activity
RK70_RS02495	COG1702	phosphate starvation-inducible protein PhoH
RK70_RS02510	COG0295	cytidine deaminase activity
RK70_RS02515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RK70_RS02530	COG0517	IMP dehydrogenase activity
RK70_RS02550	COG2384	SAM-dependent methyltransferase
RK70_RS02560	COG0513	Belongs to the DEAD box helicase family
RK70_RS02570	COG1121	(ABC) transporter
RK70_RS02575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK70_RS02600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RK70_RS02610	COG4483	Protein conserved in bacteria
RK70_RS02615	COG1940	carbohydrate kinase activity
RK70_RS02620	COG0011	TIGRFAM Protein of
RK70_RS02625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK70_RS02630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RK70_RS02635	COG1459	type II secretion system
RK70_RS02640	COG4537	Required for transformation and DNA binding
RK70_RS02685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK70_RS02690	COG0095	Lipoate-protein ligase
RK70_RS02705	COG0006	proline dipeptidase activity
RK70_RS02715	COG0511	ligase activity, forming carbon-carbon bonds
RK70_RS02720	COG0439	Biotin carboxylase
RK70_RS02725	COG1302	Protein conserved in bacteria
RK70_RS02755	COG0497	DNA recombination
RK70_RS02760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK70_RS02765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RK70_RS02770	COG0022	dehydrogenase e1 component
RK70_RS02775	COG0508	dehydrogenase complex catalyzes the overall conversion of
RK70_RS02785	COG4129	membrane
RK70_RS02795	COG2195	Cleaves the N-terminal amino acid of tripeptides
RK70_RS02815	COG1609	Transcriptional regulator
RK70_RS02820	COG0366	Alpha amylase catalytic
RK70_RS02830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RK70_RS02845	COG4221	oxidoreductase activity
RK70_RS02855	COG0667	Aldo Keto reductase
RK70_RS02860	COG0494	nUDIX hydrolase
RK70_RS02865	COG0735	belongs to the Fur family
RK70_RS02890	COG1187	pseudouridine synthase activity
RK70_RS02895	COG0745	RESPONSE REGULATOR receiver
RK70_RS02900	COG5002	protein histidine kinase activity
RK70_RS02945	COG1141	Ferredoxin
RK70_RS02955	COG0514	ATP-dependent DNA helicase (RecQ)
RK70_RS02970	COG0492	ferredoxin-NADP+ reductase activity
RK70_RS03035	COG0142	geranyltranstransferase activity
RK70_RS03055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RK70_RS03070	COG5582	Belongs to the UPF0302 family
RK70_RS03075	COG4347	Protein of unknown function (DUF1405)
RK70_RS03080	COG2738	Putative neutral zinc metallopeptidase
RK70_RS03085	COG1694	Mazg nucleotide pyrophosphohydrolase
RK70_RS03090	COG0438	transferase activity, transferring glycosyl groups
RK70_RS03115	COG3935	DnaD domain protein
RK70_RS03120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RK70_RS03130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RK70_RS03130	COG4499	WXG100 protein secretion system (Wss), protein YukC
RK70_RS03170	COG0116	Belongs to the methyltransferase superfamily
RK70_RS03185	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RK70_RS03190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK70_RS03195	COG0686	Belongs to the AlaDH PNT family
RK70_RS03205	COG0531	amino acid
RK70_RS03230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RK70_RS03245	COG1413	lyase activity
RK70_RS03305	COG0671	phosphoesterase, PA-phosphatase related
RK70_RS03350	COG0714	Associated with various cellular activities
RK70_RS03355	COG4548	von Willebrand factor, type A
RK70_RS03435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RK70_RS03440	COG0527	aspartate kinase activity
RK70_RS03445	COG0488	(ABC) transporter
RK70_RS03465	COG0573	inorganic phosphate transmembrane transporter activity
RK70_RS03470	COG0581	inorganic phosphate transmembrane transporter activity
RK70_RS03480	COG0704	Plays a role in the regulation of phosphate uptake
RK70_RS03525	COG0561	phosphatase activity
RK70_RS03565	COG0512	Glutamine amidotransferase of anthranilate synthase
RK70_RS03570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK70_RS03575	COG1363	Peptidase, m42
RK70_RS03580	COG0287	Prephenate dehydrogenase
RK70_RS03585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RK70_RS03605	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RK70_RS03605	COG0392	lysyltransferase activity
RK70_RS03610	COG0628	permease
RK70_RS03625	COG1115	amino acid carrier protein
RK70_RS03635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RK70_RS03665	COG0824	Thioesterase
RK70_RS03680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK70_RS03700	COG4846	Membrane protein involved in cytochrome C biogenesis
RK70_RS03735	COG2340	Cysteine-rich secretory protein family
RK70_RS03765	COG0833	amino acid
RK70_RS03790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RK70_RS03795	COG0460	homoserine dehydrogenase
RK70_RS03800	COG0527	aspartate kinase activity
RK70_RS03815	COG1525	nuclease
RK70_RS03825	COG2197	response regulator
RK70_RS03840	COG1131	(ABC) transporter
RK70_RS03960	COG0789	Transcriptional regulator
RK70_RS03965	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RK70_RS03980	COG1923	regulation of RNA biosynthetic process
RK70_RS04005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RK70_RS04010	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RK70_RS04020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK70_RS04045	COG1013	pyruvate-flavodoxin oxidoreductase activity
RK70_RS04050	COG0674	pyruvate-flavodoxin oxidoreductase activity
RK70_RS04050	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RK70_RS04055	COG1692	metallophosphoesterase
RK70_RS04075	COG1058	Belongs to the CinA family
RK70_RS04075	COG1546	Belongs to the CinA family
RK70_RS04095	COG0300	oxidoreductase activity
RK70_RS04100	COG0612	Peptidase, M16
RK70_RS04105	COG0612	Peptidase, M16
RK70_RS04110	COG2188	Transcriptional regulator
RK70_RS04140	COG0196	riboflavin kinase activity
RK70_RS04165	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RK70_RS04170	COG0195	Participates in both transcription termination and antitermination
RK70_RS04270	COG0758	DNA mediated transformation
RK70_RS04330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RK70_RS04340	COG0552	protein localization to endoplasmic reticulum
RK70_RS04345	COG1196	nuclear chromosome segregation
RK70_RS04385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RK70_RS04395	COG1302	Protein conserved in bacteria
RK70_RS04410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK70_RS04425	COG0631	protein serine/threonine phosphatase activity
RK70_RS04435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RK70_RS04435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RK70_RS04450	COG2314	TM2 domain
RK70_RS04460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RK70_RS04465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RK70_RS04480	COG1293	RNA-binding protein homologous to eukaryotic snRNP
RK70_RS04525	COG2233	PERMEase
RK70_RS04535	COG0564	pseudouridine synthase activity
RK70_RS04555	COG2514	catechol 2,3-dioxygenase activity
RK70_RS04565	COG3599	regulation of cell shape
RK70_RS04570	COG2302	S4 RNA-binding domain
RK70_RS04575	COG0762	integral membrane protein
RK70_RS04585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RK70_RS04600	COG0849	cell division
RK70_RS04605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RK70_RS04625	COG4839	cell division protein FtsL
RK70_RS04650	COG1011	Hydrolase
RK70_RS04685	COG1288	antiporter activity
RK70_RS04800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RK70_RS04805	COG1053	succinate dehydrogenase
RK70_RS04810	COG2009	succinate dehydrogenase
RK70_RS04835	COG1796	DNA polymerase
RK70_RS04835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RK70_RS04845	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
RK70_RS04870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RK70_RS04885	COG4509	Sortase family
RK70_RS04895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK70_RS04950	COG0742	ribosomal rna small subunit methyltransferase
RK70_RS04970	COG3679	Belongs to the UPF0342 family
RK70_RS05005	COG0772	Belongs to the SEDS family
RK70_RS05015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RK70_RS05035	COG0483	inositol monophosphate 1-phosphatase activity
RK70_RS05060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RK70_RS05065	COG1177	transmembrane transport
RK70_RS05070	COG1176	ABC-type spermidine putrescine transport system, permease component I
RK70_RS05135	COG0569	domain protein
RK70_RS05140	COG1294	oxidase, subunit
RK70_RS05145	COG1271	oxidase subunit
RK70_RS05170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RK70_RS05195	COG4721	ABC-type cobalt transport system, permease component
RK70_RS05200	COG4172	Belongs to the ABC transporter superfamily
RK70_RS05205	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RK70_RS05215	COG0138	bifunctional purine biosynthesis protein purh
RK70_RS05245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RK70_RS05260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RK70_RS05300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RK70_RS05305	COG1316	TRANSCRIPTIONal
RK70_RS05320	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK70_RS05320	COG3266	domain, Protein
RK70_RS05320	COG4193	domain, Protein
RK70_RS05335	COG3594	Acyltransferase
RK70_RS05340	COG0436	Aminotransferase
RK70_RS05365	COG2267	carboxylic ester hydrolase activity
RK70_RS05375	COG1169	isochorismate synthase
RK70_RS05385	COG1575	Belongs to the MenA family. Type 1 subfamily
RK70_RS05390	COG0456	acetyltransferase
RK70_RS05395	COG2314	TM2 domain
RK70_RS05405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK70_RS05465	COG4873	Protein conserved in bacteria
RK70_RS05480	COG4903	ComK protein
RK70_RS05495	COG0737	Belongs to the 5'-nucleotidase family
RK70_RS05500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK70_RS05505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK70_RS05510	COG0861	Integral membrane protein TerC family
RK70_RS05550	COG1115	amino acid carrier protein
RK70_RS05555	COG0628	permease
RK70_RS05560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RK70_RS05565	COG0475	glutathione-regulated potassium exporter activity
RK70_RS05565	COG0569	domain protein
RK70_RS05570	COG2239	Acts as a magnesium transporter
RK70_RS05575	COG0564	pseudouridine synthase activity
RK70_RS05585	COG2357	RelA SpoT domain protein
RK70_RS05600	COG2346	COG2346, Truncated hemoglobins
RK70_RS05610	COG1164	Oligoendopeptidase f
RK70_RS05635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK70_RS05640	COG0601	transmembrane transport
RK70_RS05645	COG4608	Belongs to the ABC transporter superfamily
RK70_RS05650	COG0444	Belongs to the ABC transporter superfamily
RK70_RS05655	COG0747	negative chemotaxis
RK70_RS05660	COG4166	transmembrane transport
RK70_RS05665	COG4608	Belongs to the ABC transporter superfamily
RK70_RS05670	COG0444	Belongs to the ABC transporter superfamily
RK70_RS05675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK70_RS05680	COG0601	transmembrane transport
RK70_RS05710	COG1881	PFAM PEBP family protein
RK70_RS05725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RK70_RS05750	COG0561	phosphatase activity
RK70_RS05790	COG0398	Pfam SNARE associated Golgi protein
RK70_RS05795	COG0166	Belongs to the GPI family
RK70_RS05810	COG0584	glycerophosphoryl diester phosphodiesterase
RK70_RS05830	COG1902	pentaerythritol trinitrate reductase activity
RK70_RS05835	COG1098	S1 RNA binding domain
RK70_RS05890	COG2050	protein possibly involved in aromatic compounds catabolism
RK70_RS05895	COG2056	Na+-H+ antiporter family
RK70_RS05900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RK70_RS05910	COG0316	Belongs to the HesB IscA family
RK70_RS05920	COG1252	NADH dehydrogenase
RK70_RS05925	COG4837	Protein of unknown function (DUF1462)
RK70_RS05930	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RK70_RS05935	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RK70_RS05945	COG1696	Membrane protein involved in D-alanine export
RK70_RS05975	COG2445	Protein of unknown function DUF86
RK70_RS05985	COG4470	Protein conserved in bacteria
RK70_RS06000	COG0730	response to heat
RK70_RS06005	COG1801	Protein of unknown function DUF72
RK70_RS06020	COG1253	flavin adenine dinucleotide binding
RK70_RS06045	COG0822	iron-sulfur transferase activity
RK70_RS06055	COG0719	Fe-S assembly protein
RK70_RS06060	COG0396	ATPase activity
RK70_RS06075	COG1464	Belongs to the NlpA lipoprotein family
RK70_RS06080	COG2011	ABC-type metal ion transport system permease component
RK70_RS06095	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK70_RS06105	COG3878	Protein conserved in bacteria
RK70_RS06120	COG1393	Belongs to the ArsC family
RK70_RS06125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK70_RS06150	COG1279	arginine transmembrane transporter activity
RK70_RS06155	COG0406	alpha-ribazole phosphatase activity
RK70_RS06195	COG1278	Cold shock
RK70_RS06220	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RK70_RS06220	COG3266	domain, Protein
RK70_RS06270	COG0557	exoribonuclease II activity
RK70_RS06275	COG1647	Serine aminopeptidase, S33
RK70_RS06280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RK70_RS06300	COG0149	triose-phosphate isomerase activity
RK70_RS06345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RK70_RS06405	COG3942	CHAP domain
RK70_RS06405	COG1388	LysM domain
RK70_RS06435	COG1040	competence protein
RK70_RS06440	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RK70_RS06450	COG1739	Uncharacterized protein family UPF0029
RK70_RS06455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RK70_RS06510	COG4607	ABC-type enterochelin transport system periplasmic component
RK70_RS06515	COG4604	ABC transporter, ATP-binding protein
RK70_RS06520	COG4605	iron ion homeostasis
RK70_RS06525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK70_RS06540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK70_RS06545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK70_RS06575	COG3104	oligopeptide transport
RK70_RS06605	COG1174	glycine betaine transport
RK70_RS06610	COG1125	glycine betaine transport
RK70_RS06610	COG0517	IMP dehydrogenase activity
RK70_RS06615	COG0514	ATP-dependent DNA helicase (RecQ)
RK70_RS06620	COG0488	(ABC) transporter
RK70_RS06650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK70_RS06655	COG0512	Glutamine amidotransferase of anthranilate synthase
RK70_RS06655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RK70_RS06665	COG0720	synthase
RK70_RS06700	COG0463	Glycosyl transferase, family 2
RK70_RS06705	COG0656	L-ascorbic acid biosynthetic process
RK70_RS06710	COG1253	flavin adenine dinucleotide binding
RK70_RS06715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RK70_RS06720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK70_RS06720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK70_RS06720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK70_RS06725	COG1105	Belongs to the carbohydrate kinase PfkB family
RK70_RS06730	COG1349	DNA-binding transcription factor activity
RK70_RS06735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RK70_RS06770	COG0471	metal ion transport
RK70_RS06780	COG4989	oxidoreductase activity
RK70_RS06785	COG0523	cobalamin synthesis protein
RK70_RS06795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RK70_RS06800	COG4988	ABC transporter
RK70_RS06820	COG1611	Belongs to the LOG family
RK70_RS06850	COG2839	Protein conserved in bacteria
RK70_RS06855	COG2814	Major facilitator Superfamily
RK70_RS06860	COG0583	DNA-binding transcription factor activity
RK70_RS06890	COG4977	sequence-specific DNA binding
RK70_RS06890	COG1917	Cupin 2, conserved barrel domain protein
RK70_RS06900	COG1388	LysM domain
RK70_RS06900	COG3942	CHAP domain
RK70_RS06905	COG0306	phosphate transporter
RK70_RS06910	COG1392	Phosphate transport regulator
RK70_RS06915	COG0577	efflux transmembrane transporter activity
RK70_RS06920	COG1136	(ABC) transporter
RK70_RS06960	COG3949	Membrane
RK70_RS06970	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RK70_RS06980	COG2376	Dihydroxyacetone kinase
RK70_RS06985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK70_RS06990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK70_RS06995	COG1120	ATPase activity
RK70_RS07000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RK70_RS07010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK70_RS07015	COG1132	(ABC) transporter
RK70_RS07020	COG1686	Belongs to the peptidase S11 family
RK70_RS07025	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RK70_RS07030	COG1216	Glycosyl transferase, family 2
RK70_RS07035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK70_RS07040	COG1682	transport, permease protein
RK70_RS07050	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RK70_RS07060	COG1321	iron dependent repressor
RK70_RS07065	COG1121	(ABC) transporter
RK70_RS07070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK70_RS07075	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK70_RS07120	COG4974	Belongs to the 'phage' integrase family
RK70_RS07170	COG4139	cobalamin transport
RK70_RS07175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK70_RS07215	COG1078	dGTPase activity
RK70_RS07225	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK70_RS07230	COG0667	Aldo Keto reductase
RK70_RS07320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK70_RS07340	COG0083	homoserine kinase activity
RK70_RS07345	COG0095	Lipoate-protein ligase
RK70_RS07445	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RK70_RS07460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RK70_RS07480	COG4932	domain protein
RK70_RS07500	COG0561	phosphatase activity
RK70_RS07510	COG1428	Deoxynucleoside kinase
RK70_RS07515	COG1428	Deoxynucleoside kinase
RK70_RS07520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RK70_RS07555	COG1473	amidohydrolase
RK70_RS07595	COG2813	Specifically methylates the guanine in position
RK70_RS07655	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RK70_RS07680	COG4956	integral membrane protein (PIN domain superfamily)
RK70_RS07685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RK70_RS07700	COG3880	PFAM UvrB UvrC protein
RK70_RS07710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK70_RS07725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK70_RS07820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RK70_RS07845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RK70_RS07860	COG1098	S1 RNA binding domain
RK70_RS07870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RK70_RS07875	COG3956	TIGRFAM MazG family protein
RK70_RS07880	COG2244	polysaccharide biosynthetic process
RK70_RS07910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RK70_RS07925	COG0251	oxidation-reduction process
RK70_RS07930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RK70_RS07940	COG4466	Protein conserved in bacteria
RK70_RS07950	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK70_RS07955	COG0084	hydrolase, TatD family'
RK70_RS07965	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RK70_RS07975	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RK70_RS07985	COG1774	PSP1 C-terminal conserved region
RK70_RS07990	COG0470	DNA polymerase III
RK70_RS07995	COG3870	Protein conserved in bacteria
RK70_RS08005	COG1982	Orn Lys Arg decarboxylase major
RK70_RS08045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RK70_RS08065	COG2188	Transcriptional regulator
RK70_RS08070	COG0366	Alpha amylase catalytic
RK70_RS08075	COG1263	PTS System
RK70_RS08075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK70_RS08085	COG0493	'glutamate synthase
RK70_RS08090	COG0067	glutamate synthase
RK70_RS08090	COG0070	glutamate synthase
RK70_RS08090	COG0069	glutamate synthase activity
RK70_RS08095	COG0583	DNA-binding transcription factor activity
RK70_RS08130	COG1464	Belongs to the NlpA lipoprotein family
RK70_RS08135	COG2011	ABC-type metal ion transport system permease component
RK70_RS08145	COG0626	cystathionine gamma-synthase activity
RK70_RS08150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RK70_RS08155	COG0733	neurotransmitter:sodium symporter activity
RK70_RS08165	COG1647	Serine aminopeptidase, S33
RK70_RS08180	COG5609	conserved protein (DUF2294)
RK70_RS08190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RK70_RS08215	COG0523	cobalamin synthesis protein
RK70_RS08345	COG3759	membrane
RK70_RS08385	COG2233	PERMEase
RK70_RS08420	COG1823	symporter activity
RK70_RS08435	COG3634	alkyl hydroperoxide reductase activity
RK70_RS08495	COG4974	Belongs to the 'phage' integrase family
RK70_RS08530	COG0012	GTP binding
RK70_RS08535	COG4481	Protein conserved in bacteria
RK70_RS08540	COG0668	transmembrane transport
RK70_RS08545	COG1475	DNA binding
RK70_RS08555	COG0626	cystathionine gamma-synthase activity
RK70_RS08560	COG0626	cystathionine gamma-synthase activity
RK70_RS08565	COG0646	methionine synthase
RK70_RS08565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RK70_RS08595	COG1131	(ABC) transporter
RK70_RS08605	COG1476	TRANSCRIPTIONal
RK70_RS08615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RK70_RS08620	COG0805	protein transport
RK70_RS08625	COG0672	)-iron permease
RK70_RS08635	COG2822	iron ion transport
RK70_RS08640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK70_RS08655	COG0431	NADPH-dependent FMN reductase
RK70_RS08660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK70_RS08665	COG0346	lactoylglutathione lyase activity
RK70_RS08670	COG2271	Major facilitator Superfamily
RK70_RS08695	COG3711	transcriptional antiterminator
RK70_RS08700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK70_RS08710	COG3037	sugar-specific permease SgaT UlaA
RK70_RS08715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RK70_RS08740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK70_RS08790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RK70_RS08795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK70_RS08825	COG0577	efflux transmembrane transporter activity
RK70_RS08835	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
RK70_RS08845	COG1114	Component of the transport system for branched-chain amino acids
RK70_RS09005	COG1388	LysM domain
RK70_RS09005	COG3942	CHAP domain
RK70_RS09035	COG1131	(ABC) transporter
RK70_RS09095	COG2226	methyltransferase
RK70_RS09105	COG2723	6-phospho-beta-galactosidase activity
RK70_RS09110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK70_RS09110	COG2190	(PTS) system
RK70_RS09110	COG1263	PTS System
RK70_RS09120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK70_RS09155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK70_RS09160	COG1063	alcohol dehydrogenase
RK70_RS09170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK70_RS09175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK70_RS09180	COG1063	alcohol dehydrogenase
RK70_RS09190	COG1063	alcohol dehydrogenase
RK70_RS09200	COG1063	alcohol dehydrogenase
RK70_RS09205	COG3775	system Galactitol-specific IIC component
RK70_RS09210	COG3414	Phosphotransferase system galactitol-specific IIB component
RK70_RS09230	COG1957	nucleoside hydrolase
RK70_RS09235	COG2190	(PTS) system
RK70_RS09235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK70_RS09235	COG1263	PTS System
RK70_RS09270	COG3189	MarR family transcriptional regulator
RK70_RS09275	COG0747	negative chemotaxis
RK70_RS09290	COG0318	PFAM AMP-dependent synthetase and ligase
RK70_RS09295	COG1960	acyl-CoA dehydrogenase activity
RK70_RS09305	COG0183	Belongs to the thiolase family
RK70_RS09365	COG1755	Isoprenylcysteine carboxyl methyltransferase
RK70_RS09375	COG0673	inositol 2-dehydrogenase activity
RK70_RS09380	COG0673	inositol 2-dehydrogenase activity
RK70_RS09385	COG3833	ABC-type maltose transport systems, permease component
RK70_RS09390	COG1175	transmembrane transport
RK70_RS09400	COG3842	ATPase activity
RK70_RS09420	COG0405	Gamma-glutamyltransferase
RK70_RS09430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK70_RS09470	COG1737	Transcriptional regulator
RK70_RS09500	COG3961	Belongs to the TPP enzyme family
RK70_RS09505	COG1335	isochorismatase
RK70_RS09510	COG1114	Component of the transport system for branched-chain amino acids
RK70_RS09560	COG5609	conserved protein (DUF2294)
RK70_RS09565	COG1960	acyl-CoA dehydrogenase activity
RK70_RS09570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RK70_RS09605	COG2832	Protein of unknown function (DUF454)
RK70_RS09615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK70_RS09620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RK70_RS09630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK70_RS09660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK70_RS09670	COG1086	Polysaccharide biosynthesis protein
RK70_RS09695	COG1454	alcohol dehydrogenase
RK70_RS09695	COG1012	belongs to the aldehyde dehydrogenase family
RK70_RS09725	COG0737	Belongs to the 5'-nucleotidase family
RK70_RS09745	COG3639	organic phosphonate transmembrane transporter activity
RK70_RS09765	COG2814	Major facilitator Superfamily
RK70_RS09770	COG0813	purine-nucleoside phosphorylase activity
RK70_RS09805	COG0438	transferase activity, transferring glycosyl groups
RK70_RS09810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK70_RS09815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK70_RS09845	COG1475	DNA binding
RK70_RS09850	COG0019	diaminopimelate decarboxylase activity
RK70_RS09860	COG4264	IucA IucC family
RK70_RS09865	COG4264	IucA IucC family
RK70_RS09870	COG2814	Major facilitator Superfamily
RK70_RS09875	COG4264	IucA IucC family
RK70_RS09880	COG2423	ornithine cyclodeaminase activity
RK70_RS09890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK70_RS09895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK70_RS09900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK70_RS09915	COG1388	LysM domain
RK70_RS09920	COG1620	l-lactate permease
RK70_RS09935	COG0697	spore germination
RK70_RS09940	COG4716	Myosin-crossreactive antigen
RK70_RS09945	COG1283	sodium-dependent phosphate transmembrane transporter activity
RK70_RS09955	COG1473	amidohydrolase
RK70_RS09985	COG0823	Involved in the tonB-independent uptake of proteins
RK70_RS10005	COG0583	DNA-binding transcription factor activity
RK70_RS10020	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK70_RS10060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK70_RS10065	COG2210	Belongs to the sulfur carrier protein TusA family
RK70_RS10070	COG1937	Protein conserved in bacteria
RK70_RS10075	COG0730	response to heat
RK70_RS10110	COG0737	Belongs to the 5'-nucleotidase family
RK70_RS10115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RK70_RS10125	COG4863	YycH protein
RK70_RS10160	COG0305	Participates in initiation and elongation during chromosome replication
RK70_RS10165	COG0359	binds to the 23S rRNA
RK70_RS10170	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RK70_RS10180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RK70_RS10210	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RK70_RS10215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RK70_RS10230	COG2501	S4 domain
RK70_RS10270	COG1475	DNA binding
RK70_RS10295	COG1278	Cold shock
RK70_RS10325	COG0577	efflux transmembrane transporter activity
RK70_RS10330	COG1136	(ABC) transporter
RK70_RS10345	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RK70_RS10355	COG2962	Rard protein
RK70_RS10360	COG0471	metal ion transport
RK70_RS10445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RK70_RS10480	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RK70_RS10535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK70_RS10555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK70_RS10575	COG1073	alpha beta
RK70_RS10590	COG0438	transferase activity, transferring glycosyl groups
RK70_RS10605	COG1535	isochorismatase
RK70_RS10605	COG3433	isochorismatase activity
RK70_RS10610	COG3942	CHAP domain
RK70_RS10610	COG1705	Flagellar rod assembly protein muramidase FlgJ
RK70_RS10620	COG1482	cell wall glycoprotein biosynthetic process
RK70_RS10625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK70_RS10625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK70_RS10625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK70_RS10630	COG3711	transcriptional antiterminator
RK70_RS10630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK70_RS10650	COG1438	arginine binding
RK70_RS10695	COG1846	Transcriptional regulator
RK70_RS10705	COG1785	Belongs to the alkaline phosphatase family
RK70_RS10715	COG0745	RESPONSE REGULATOR receiver
RK70_RS10720	COG2205	protein histidine kinase activity
RK70_RS10725	COG1136	(ABC) transporter
RK70_RS10750	COG0386	Belongs to the glutathione peroxidase family
RK70_RS10760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RK70_RS10775	COG2851	Citrate transporter
RK70_RS10800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK70_RS10810	COG1510	regulation of RNA biosynthetic process
RK70_RS10820	COG1012	belongs to the aldehyde dehydrogenase family
RK70_RS10840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK70_RS10870	COG0531	amino acid
RK70_RS10885	COG3527	Alpha-acetolactate decarboxylase
RK70_RS10890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK70_RS10900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RK70_RS10940	COG0167	dihydroorotate dehydrogenase activity
RK70_RS10945	COG3001	Fructosamine kinase
RK70_RS10985	COG0596	Alpha beta hydrolase
RK70_RS11030	COG1309	transcriptional regulator
RK70_RS11055	COG2755	lipolytic protein G-D-S-L family
RK70_RS11055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RK70_RS11060	COG3942	CHAP domain
RK70_RS11090	COG0436	Aminotransferase
RK70_RS11135	COG2409	Drug exporters of the RND superfamily
RK70_RS11155	COG0542	response to heat
RK70_RS11160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RK70_RS11165	COG3425	synthase
RK70_RS11190	COG3942	CHAP domain
RK70_RS11200	COG0583	DNA-binding transcription factor activity
RK70_RS11215	COG0028	Belongs to the TPP enzyme family
RK70_RS11235	COG0657	acetylesterase activity
RK70_RS11240	COG0697	spore germination
RK70_RS11255	COG1760	l-serine dehydratase
RK70_RS11260	COG1760	l-serine dehydratase
RK70_RS11280	COG3764	Sortase (surface protein transpeptidase)
RK70_RS11290	COG1131	(ABC) transporter
RK70_RS11295	COG0561	phosphatase activity
RK70_RS11310	COG2514	catechol 2,3-dioxygenase activity
RK70_RS11320	COG1846	Transcriptional regulator
RK70_RS11325	COG0346	lactoylglutathione lyase activity
RK70_RS11330	COG0400	carboxylic ester hydrolase activity
RK70_RS11350	COG1131	(ABC) transporter
RK70_RS11365	COG1846	Transcriptional regulator
RK70_RS11370	COG2814	Major facilitator Superfamily
RK70_RS11380	COG0586	Pfam SNARE associated Golgi protein
RK70_RS11385	COG2271	Major facilitator Superfamily
RK70_RS11395	COG4876	unkown
RK70_RS11400	COG2357	RelA SpoT domain protein
RK70_RS11405	COG0789	Transcriptional regulator
RK70_RS11410	COG1802	Transcriptional regulator
RK70_RS11415	COG1070	Carbohydrate kinase
RK70_RS11435	COG4932	domain protein
RK70_RS11450	COG1846	Transcriptional regulator
RK70_RS11455	COG1846	Transcriptional regulator
RK70_RS11460	COG3583	domain protein
RK70_RS11495	COG0494	nUDIX hydrolase
RK70_RS11585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK70_RS11590	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RK70_RS11620	COG0747	negative chemotaxis
RK70_RS11625	COG0601	transmembrane transport
RK70_RS11630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK70_RS11635	COG0444	Belongs to the ABC transporter superfamily
RK70_RS11640	COG1124	(ABC) transporter
RK70_RS11655	COG0069	glutamate synthase activity
RK70_RS11660	COG4808	Protein conserved in bacteria
RK70_RS11680	COG1363	Peptidase, m42
RK70_RS11685	COG4619	ABC transporter
RK70_RS11690	COG0390	transport system, permease component
RK70_RS11695	COG2814	Major facilitator Superfamily
RK70_RS11700	COG2272	Belongs to the type-B carboxylesterase lipase family
RK70_RS11705	COG0531	amino acid
RK70_RS11715	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RK70_RS11735	COG1174	glycine betaine transport
RK70_RS11745	COG1174	glycine betaine transport
RK70_RS11755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK70_RS11770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RK70_RS11780	COG0531	amino acid
RK70_RS11795	COG1113	amino acid transport
RK70_RS11815	COG2814	Major facilitator Superfamily
RK70_RS11825	COG1929	Belongs to the glycerate kinase type-1 family
RK70_RS11850	COG1132	(ABC) transporter
RK70_RS11865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RK70_RS11870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RK70_RS11880	COG0156	8-amino-7-oxononanoate synthase activity
RK70_RS11930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RK70_RS11950	COG2814	Major facilitator Superfamily
RK70_RS11955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK70_RS11960	COG0765	amino acid transport
RK70_RS11965	COG1126	abc transporter atp-binding protein
RK70_RS12005	COG3443	Belongs to the bacterial solute-binding protein 9 family
RK70_RS12005	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK70_RS12020	COG2116	formate transmembrane transporter activity
RK70_RS12025	COG0454	-acetyltransferase
RK70_RS12035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RK70_RS12040	COG2146	nitrite reductase [NAD(P)H] activity
RK70_RS12050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RK70_RS12055	COG1140	nitrate reductase beta subunit
RK70_RS12065	COG2181	nitrate reductase activity
RK70_RS12085	COG0789	Transcriptional regulator
RK70_RS12125	COG3871	stress protein (general stress protein 26)
RK70_RS12140	COG1263	PTS System
RK70_RS12140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK70_RS12155	COG1511	domain protein
RK70_RS12180	COG0456	acetyltransferase
RK70_RS12185	COG0604	alcohol dehydrogenase
RK70_RS12205	COG1620	l-lactate permease
RK70_RS12275	COG2814	Major facilitator Superfamily
RK70_RS12285	COG1566	PFAM secretion protein HlyD family protein
RK70_RS12290	COG2814	Major facilitator Superfamily
RK70_RS12300	COG0657	acetylesterase activity
RK70_RS12315	COG0598	Magnesium transport protein CorA
RK70_RS12325	COG0786	glutamate:sodium symporter activity
RK70_RS12340	COG3152	Membrane
RK70_RS12345	COG4152	abc transporter atp-binding protein
RK70_RS12350	COG1668	transmembrane transport
RK70_RS12370	COG2258	MOSC domain
RK70_RS12395	COG0583	DNA-binding transcription factor activity
RK70_RS12410	COG1473	amidohydrolase
RK70_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
RK70_RS12435	COG1737	Transcriptional regulator
RK70_RS12440	COG1263	PTS System
RK70_RS12440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK70_RS12450	COG0385	Bile acid
RK70_RS12455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK70_RS12475	COG1113	amino acid transport
RK70_RS12550	COG3942	CHAP domain
RK70_RS12565	COG1757	Na H antiporter
RK70_RS12575	COG3942	CHAP domain
RK70_RS12640	COG4413	Urea transporter
RK70_RS12645	COG1960	acyl-CoA dehydrogenase activity
RK70_RS12660	COG1268	BioY protein
RK70_RS12675	COG0725	ABC transporter, periplasmic molybdate-binding protein
RK70_RS12680	COG4149	molybdate abc transporter
RK70_RS12685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RK70_RS12690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RK70_RS12710	COG1763	Mo-molybdopterin cofactor biosynthetic process
RK70_RS12785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK70_RS12825	COG0551	DNA topoisomerase type I activity
RK70_RS12825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RK70_RS12830	COG2252	PERMEase
RK70_RS12945	COG0201	protein transport
RK70_RS13030	COG0542	response to heat
RK70_RS13050	COG0028	Belongs to the TPP enzyme family
RK70_RS13055	COG3527	Alpha-acetolactate decarboxylase
RK70_RS13075	COG5492	domain, Protein
RK70_RS13085	COG0789	Transcriptional regulator
RK70_RS13090	COG0656	L-ascorbic acid biosynthetic process
RK70_RS13110	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RK70_RS13160	COG2130	NADP-dependent
RK70_RS13170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK70_RS13200	COG2814	Major facilitator Superfamily
RK70_RS13205	COG4264	IucA IucC family
RK70_RS13210	COG3457	Alanine racemase
RK70_RS13220	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK70_RS13225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK70_RS13230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK70_RS13245	COG1988	membrane-bound metal-dependent
RK70_RS13255	COG1272	protein, Hemolysin III
RK70_RS13270	COG2814	Major facilitator Superfamily
RK70_RS13275	COG0489	protein tyrosine kinase activity
RK70_RS13350	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RK70_RS13370	COG0246	Mannitol dehydrogenase
RK70_RS13380	COG3711	transcriptional antiterminator
RK70_RS13395	COG1119	ATPase activity
RK70_RS13400	COG0561	phosphatase activity
RK70_RS13435	COG0640	Transcriptional regulator
RK70_RS13440	COG0702	epimerase
RK70_RS13470	COG0783	Belongs to the Dps family
RK70_RS13475	COG0813	purine-nucleoside phosphorylase activity
RK70_RS13525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK70_RS13535	COG0504	CTP synthase activity
RK70_RS13565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RK70_RS13590	COG2890	protein-(glutamine-N5) methyltransferase activity
RK70_RS13595	COG0009	L-threonylcarbamoyladenylate synthase
RK70_RS13620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK70_RS13695	COG0629	single-stranded DNA binding
RK70_RS13705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RK70_RS13745	COG1418	mRNA catabolic process
RK70_RS13755	COG1937	Protein conserved in bacteria
RK70_RS13770	COG0772	Belongs to the SEDS family
RK70_RS13780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RK70_RS13790	COG0745	RESPONSE REGULATOR receiver
RK70_RS13795	COG2205	protein histidine kinase activity
RK70_RS13825	COG3428	Bacterial PH domain
RK70_RS13865	COG1366	Belongs to the anti-sigma-factor antagonist family
RK70_RS13875	COG1191	sigma factor activity
RK70_RS13880	COG2183	response to ionizing radiation
RK70_RS13915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK70_RS14040	COG3682	Transcriptional regulator