locus-tag	class	description
RK85_RS00015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RK85_RS00035	COG0483	inositol monophosphate 1-phosphatase activity
RK85_RS00060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RK85_RS00065	COG1177	transmembrane transport
RK85_RS00070	COG1176	ABC-type spermidine putrescine transport system, permease component I
RK85_RS00135	COG0569	domain protein
RK85_RS00140	COG1294	oxidase, subunit
RK85_RS00145	COG1271	oxidase subunit
RK85_RS00170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RK85_RS00195	COG4721	ABC-type cobalt transport system, permease component
RK85_RS00200	COG4172	Belongs to the ABC transporter superfamily
RK85_RS00205	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RK85_RS00215	COG0138	bifunctional purine biosynthesis protein purh
RK85_RS00245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RK85_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RK85_RS00300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RK85_RS00305	COG1316	TRANSCRIPTIONal
RK85_RS00320	COG3266	domain, Protein
RK85_RS00320	COG4193	domain, Protein
RK85_RS00320	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK85_RS00335	COG3594	Acyltransferase
RK85_RS00340	COG0436	Aminotransferase
RK85_RS00365	COG2267	carboxylic ester hydrolase activity
RK85_RS00375	COG1169	isochorismate synthase
RK85_RS00385	COG1575	Belongs to the MenA family. Type 1 subfamily
RK85_RS00390	COG0456	acetyltransferase
RK85_RS00395	COG2314	TM2 domain
RK85_RS00405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK85_RS00465	COG4873	Protein conserved in bacteria
RK85_RS00480	COG4903	ComK protein
RK85_RS00495	COG0737	Belongs to the 5'-nucleotidase family
RK85_RS00500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK85_RS00505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK85_RS00510	COG0861	Integral membrane protein TerC family
RK85_RS00550	COG1115	amino acid carrier protein
RK85_RS00555	COG0628	permease
RK85_RS00560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RK85_RS00565	COG0569	domain protein
RK85_RS00565	COG0475	glutathione-regulated potassium exporter activity
RK85_RS00570	COG2239	Acts as a magnesium transporter
RK85_RS00575	COG0564	pseudouridine synthase activity
RK85_RS00585	COG2357	RelA SpoT domain protein
RK85_RS00600	COG2346	COG2346, Truncated hemoglobins
RK85_RS00610	COG1164	Oligoendopeptidase f
RK85_RS00635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK85_RS00640	COG0601	transmembrane transport
RK85_RS00645	COG4608	Belongs to the ABC transporter superfamily
RK85_RS00650	COG0444	Belongs to the ABC transporter superfamily
RK85_RS00655	COG0747	negative chemotaxis
RK85_RS00660	COG4166	transmembrane transport
RK85_RS00665	COG4608	Belongs to the ABC transporter superfamily
RK85_RS00670	COG0444	Belongs to the ABC transporter superfamily
RK85_RS00675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK85_RS00680	COG0601	transmembrane transport
RK85_RS00710	COG1881	PFAM PEBP family protein
RK85_RS00725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RK85_RS00750	COG0561	phosphatase activity
RK85_RS00790	COG0398	Pfam SNARE associated Golgi protein
RK85_RS00795	COG0166	Belongs to the GPI family
RK85_RS00810	COG0584	glycerophosphoryl diester phosphodiesterase
RK85_RS00830	COG1902	pentaerythritol trinitrate reductase activity
RK85_RS00835	COG1098	S1 RNA binding domain
RK85_RS00890	COG2050	protein possibly involved in aromatic compounds catabolism
RK85_RS00895	COG2056	Na+-H+ antiporter family
RK85_RS00900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RK85_RS00910	COG0316	Belongs to the HesB IscA family
RK85_RS00920	COG1252	NADH dehydrogenase
RK85_RS00925	COG4837	Protein of unknown function (DUF1462)
RK85_RS00930	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RK85_RS00935	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RK85_RS00945	COG1696	Membrane protein involved in D-alanine export
RK85_RS00975	COG2445	Protein of unknown function DUF86
RK85_RS00985	COG4470	Protein conserved in bacteria
RK85_RS01000	COG0730	response to heat
RK85_RS01005	COG1801	Protein of unknown function DUF72
RK85_RS01020	COG1253	flavin adenine dinucleotide binding
RK85_RS01045	COG0822	iron-sulfur transferase activity
RK85_RS01055	COG0719	Fe-S assembly protein
RK85_RS01060	COG0396	ATPase activity
RK85_RS01075	COG1464	Belongs to the NlpA lipoprotein family
RK85_RS01080	COG2011	ABC-type metal ion transport system permease component
RK85_RS01095	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK85_RS01105	COG3878	Protein conserved in bacteria
RK85_RS01120	COG1393	Belongs to the ArsC family
RK85_RS01125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK85_RS01150	COG1279	arginine transmembrane transporter activity
RK85_RS01155	COG0406	alpha-ribazole phosphatase activity
RK85_RS01195	COG1278	Cold shock
RK85_RS01220	COG3266	domain, Protein
RK85_RS01220	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RK85_RS01270	COG0557	exoribonuclease II activity
RK85_RS01275	COG1647	Serine aminopeptidase, S33
RK85_RS01280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RK85_RS01300	COG0149	triose-phosphate isomerase activity
RK85_RS01345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RK85_RS01405	COG1388	LysM domain
RK85_RS01405	COG3942	CHAP domain
RK85_RS01435	COG1040	competence protein
RK85_RS01440	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RK85_RS01450	COG1739	Uncharacterized protein family UPF0029
RK85_RS01455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RK85_RS01510	COG4607	ABC-type enterochelin transport system periplasmic component
RK85_RS01515	COG4604	ABC transporter, ATP-binding protein
RK85_RS01520	COG4605	iron ion homeostasis
RK85_RS01525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK85_RS01540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK85_RS01545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK85_RS01575	COG3104	oligopeptide transport
RK85_RS01605	COG1174	glycine betaine transport
RK85_RS01610	COG1125	glycine betaine transport
RK85_RS01610	COG0517	IMP dehydrogenase activity
RK85_RS01615	COG0514	ATP-dependent DNA helicase (RecQ)
RK85_RS01620	COG0488	(ABC) transporter
RK85_RS01650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK85_RS01655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RK85_RS01655	COG0512	Glutamine amidotransferase of anthranilate synthase
RK85_RS01665	COG0720	synthase
RK85_RS01700	COG0463	Glycosyl transferase, family 2
RK85_RS01705	COG0656	L-ascorbic acid biosynthetic process
RK85_RS01710	COG1253	flavin adenine dinucleotide binding
RK85_RS01715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RK85_RS01720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK85_RS01720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK85_RS01720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK85_RS01725	COG1105	Belongs to the carbohydrate kinase PfkB family
RK85_RS01730	COG1349	DNA-binding transcription factor activity
RK85_RS01735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RK85_RS01770	COG0471	metal ion transport
RK85_RS01780	COG4989	oxidoreductase activity
RK85_RS01785	COG0523	cobalamin synthesis protein
RK85_RS01795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RK85_RS01800	COG4988	ABC transporter
RK85_RS01820	COG1611	Belongs to the LOG family
RK85_RS01850	COG2839	Protein conserved in bacteria
RK85_RS01855	COG2814	Major facilitator Superfamily
RK85_RS01860	COG0583	DNA-binding transcription factor activity
RK85_RS01890	COG1917	Cupin 2, conserved barrel domain protein
RK85_RS01890	COG4977	sequence-specific DNA binding
RK85_RS01900	COG1388	LysM domain
RK85_RS01900	COG3942	CHAP domain
RK85_RS01905	COG0306	phosphate transporter
RK85_RS01910	COG1392	Phosphate transport regulator
RK85_RS01915	COG0577	efflux transmembrane transporter activity
RK85_RS01920	COG1136	(ABC) transporter
RK85_RS01935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK85_RS01960	COG3949	Membrane
RK85_RS01970	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RK85_RS01980	COG2376	Dihydroxyacetone kinase
RK85_RS01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK85_RS01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK85_RS01995	COG1120	ATPase activity
RK85_RS02000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RK85_RS02010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK85_RS02015	COG1132	(ABC) transporter
RK85_RS02020	COG1686	Belongs to the peptidase S11 family
RK85_RS02025	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RK85_RS02030	COG1216	Glycosyl transferase, family 2
RK85_RS02035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK85_RS02040	COG1682	transport, permease protein
RK85_RS02050	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RK85_RS02060	COG1321	iron dependent repressor
RK85_RS02065	COG1121	(ABC) transporter
RK85_RS02070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK85_RS02075	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK85_RS02120	COG4974	Belongs to the 'phage' integrase family
RK85_RS02170	COG4139	cobalamin transport
RK85_RS02175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK85_RS02215	COG1078	dGTPase activity
RK85_RS02225	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK85_RS02230	COG0667	Aldo Keto reductase
RK85_RS02320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK85_RS02340	COG0083	homoserine kinase activity
RK85_RS02345	COG0095	Lipoate-protein ligase
RK85_RS02445	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RK85_RS02460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RK85_RS02480	COG4932	domain protein
RK85_RS02500	COG0561	phosphatase activity
RK85_RS02510	COG1428	Deoxynucleoside kinase
RK85_RS02515	COG1428	Deoxynucleoside kinase
RK85_RS02520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RK85_RS02555	COG1473	amidohydrolase
RK85_RS02595	COG2813	Specifically methylates the guanine in position
RK85_RS02655	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RK85_RS02680	COG4956	integral membrane protein (PIN domain superfamily)
RK85_RS02685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RK85_RS02700	COG3880	PFAM UvrB UvrC protein
RK85_RS02710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK85_RS02725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK85_RS02820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RK85_RS02845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RK85_RS02860	COG1098	S1 RNA binding domain
RK85_RS02870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RK85_RS02875	COG3956	TIGRFAM MazG family protein
RK85_RS02880	COG2244	polysaccharide biosynthetic process
RK85_RS02910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RK85_RS02925	COG0251	oxidation-reduction process
RK85_RS02930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RK85_RS02940	COG4466	Protein conserved in bacteria
RK85_RS02950	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK85_RS02955	COG0084	hydrolase, TatD family'
RK85_RS02965	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RK85_RS02975	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RK85_RS02985	COG1774	PSP1 C-terminal conserved region
RK85_RS02990	COG0470	DNA polymerase III
RK85_RS02995	COG3870	Protein conserved in bacteria
RK85_RS03005	COG1982	Orn Lys Arg decarboxylase major
RK85_RS03045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RK85_RS03065	COG2188	Transcriptional regulator
RK85_RS03070	COG0366	Alpha amylase catalytic
RK85_RS03075	COG1263	PTS System
RK85_RS03075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK85_RS03085	COG0493	'glutamate synthase
RK85_RS03090	COG0067	glutamate synthase
RK85_RS03090	COG0069	glutamate synthase activity
RK85_RS03090	COG0070	glutamate synthase
RK85_RS03095	COG0583	DNA-binding transcription factor activity
RK85_RS03130	COG1464	Belongs to the NlpA lipoprotein family
RK85_RS03135	COG2011	ABC-type metal ion transport system permease component
RK85_RS03145	COG0626	cystathionine gamma-synthase activity
RK85_RS03150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RK85_RS03155	COG0733	neurotransmitter:sodium symporter activity
RK85_RS03165	COG1647	Serine aminopeptidase, S33
RK85_RS03180	COG5609	conserved protein (DUF2294)
RK85_RS03190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RK85_RS03215	COG0523	cobalamin synthesis protein
RK85_RS03345	COG3759	membrane
RK85_RS03385	COG2233	PERMEase
RK85_RS03420	COG1823	symporter activity
RK85_RS03435	COG3634	alkyl hydroperoxide reductase activity
RK85_RS03495	COG4974	Belongs to the 'phage' integrase family
RK85_RS03530	COG0012	GTP binding
RK85_RS03535	COG4481	Protein conserved in bacteria
RK85_RS03540	COG0668	transmembrane transport
RK85_RS03545	COG1475	DNA binding
RK85_RS03555	COG0626	cystathionine gamma-synthase activity
RK85_RS03560	COG0626	cystathionine gamma-synthase activity
RK85_RS03565	COG0646	methionine synthase
RK85_RS03565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RK85_RS03595	COG1131	(ABC) transporter
RK85_RS03605	COG1476	TRANSCRIPTIONal
RK85_RS03615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RK85_RS03620	COG0805	protein transport
RK85_RS03625	COG0672	)-iron permease
RK85_RS03635	COG2822	iron ion transport
RK85_RS03640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK85_RS03655	COG0431	NADPH-dependent FMN reductase
RK85_RS03660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK85_RS03665	COG0346	lactoylglutathione lyase activity
RK85_RS03670	COG2271	Major facilitator Superfamily
RK85_RS03695	COG3711	transcriptional antiterminator
RK85_RS03700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK85_RS03710	COG3037	sugar-specific permease SgaT UlaA
RK85_RS03715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RK85_RS03740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK85_RS03790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RK85_RS03795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK85_RS03825	COG0577	efflux transmembrane transporter activity
RK85_RS03835	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
RK85_RS03845	COG1114	Component of the transport system for branched-chain amino acids
RK85_RS04005	COG1388	LysM domain
RK85_RS04005	COG3942	CHAP domain
RK85_RS04035	COG1131	(ABC) transporter
RK85_RS04095	COG2226	methyltransferase
RK85_RS04105	COG2723	6-phospho-beta-galactosidase activity
RK85_RS04110	COG1263	PTS System
RK85_RS04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK85_RS04110	COG2190	(PTS) system
RK85_RS04120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK85_RS04155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK85_RS04160	COG1063	alcohol dehydrogenase
RK85_RS04170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK85_RS04175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK85_RS04180	COG1063	alcohol dehydrogenase
RK85_RS04190	COG1063	alcohol dehydrogenase
RK85_RS04200	COG1063	alcohol dehydrogenase
RK85_RS04205	COG3775	system Galactitol-specific IIC component
RK85_RS04210	COG3414	Phosphotransferase system galactitol-specific IIB component
RK85_RS04230	COG1957	nucleoside hydrolase
RK85_RS04235	COG1263	PTS System
RK85_RS04235	COG2190	(PTS) system
RK85_RS04235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK85_RS04270	COG3189	MarR family transcriptional regulator
RK85_RS04275	COG0747	negative chemotaxis
RK85_RS04290	COG0318	PFAM AMP-dependent synthetase and ligase
RK85_RS04295	COG1960	acyl-CoA dehydrogenase activity
RK85_RS04305	COG0183	Belongs to the thiolase family
RK85_RS04365	COG1755	Isoprenylcysteine carboxyl methyltransferase
RK85_RS04375	COG0673	inositol 2-dehydrogenase activity
RK85_RS04380	COG0673	inositol 2-dehydrogenase activity
RK85_RS04385	COG3833	ABC-type maltose transport systems, permease component
RK85_RS04390	COG1175	transmembrane transport
RK85_RS04400	COG3842	ATPase activity
RK85_RS04420	COG0405	Gamma-glutamyltransferase
RK85_RS04430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK85_RS04470	COG1737	Transcriptional regulator
RK85_RS04500	COG3961	Belongs to the TPP enzyme family
RK85_RS04505	COG1335	isochorismatase
RK85_RS04510	COG1114	Component of the transport system for branched-chain amino acids
RK85_RS04560	COG5609	conserved protein (DUF2294)
RK85_RS04565	COG1960	acyl-CoA dehydrogenase activity
RK85_RS04570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RK85_RS04605	COG2832	Protein of unknown function (DUF454)
RK85_RS04615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK85_RS04620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RK85_RS04630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK85_RS04660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK85_RS04670	COG1086	Polysaccharide biosynthesis protein
RK85_RS04695	COG1454	alcohol dehydrogenase
RK85_RS04695	COG1012	belongs to the aldehyde dehydrogenase family
RK85_RS04725	COG0737	Belongs to the 5'-nucleotidase family
RK85_RS04745	COG3639	organic phosphonate transmembrane transporter activity
RK85_RS04765	COG2814	Major facilitator Superfamily
RK85_RS04770	COG0813	purine-nucleoside phosphorylase activity
RK85_RS04805	COG0438	transferase activity, transferring glycosyl groups
RK85_RS04810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK85_RS04815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK85_RS04845	COG1475	DNA binding
RK85_RS04850	COG0019	diaminopimelate decarboxylase activity
RK85_RS04860	COG4264	IucA IucC family
RK85_RS04865	COG4264	IucA IucC family
RK85_RS04870	COG2814	Major facilitator Superfamily
RK85_RS04875	COG4264	IucA IucC family
RK85_RS04880	COG2423	ornithine cyclodeaminase activity
RK85_RS04890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK85_RS04895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK85_RS04900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK85_RS04915	COG1388	LysM domain
RK85_RS04920	COG1620	l-lactate permease
RK85_RS04935	COG0697	spore germination
RK85_RS04940	COG4716	Myosin-crossreactive antigen
RK85_RS04945	COG1283	sodium-dependent phosphate transmembrane transporter activity
RK85_RS04955	COG1473	amidohydrolase
RK85_RS04985	COG0823	Involved in the tonB-independent uptake of proteins
RK85_RS05005	COG0583	DNA-binding transcription factor activity
RK85_RS05020	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK85_RS05060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK85_RS05065	COG2210	Belongs to the sulfur carrier protein TusA family
RK85_RS05070	COG1937	Protein conserved in bacteria
RK85_RS05075	COG0730	response to heat
RK85_RS05110	COG0737	Belongs to the 5'-nucleotidase family
RK85_RS05115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RK85_RS05125	COG4863	YycH protein
RK85_RS05160	COG0305	Participates in initiation and elongation during chromosome replication
RK85_RS05165	COG0359	binds to the 23S rRNA
RK85_RS05170	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RK85_RS05180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RK85_RS05210	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RK85_RS05215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RK85_RS05230	COG2501	S4 domain
RK85_RS05270	COG1475	DNA binding
RK85_RS05295	COG1278	Cold shock
RK85_RS05325	COG0577	efflux transmembrane transporter activity
RK85_RS05330	COG1136	(ABC) transporter
RK85_RS05345	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RK85_RS05355	COG2962	Rard protein
RK85_RS05360	COG0471	metal ion transport
RK85_RS05445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RK85_RS05480	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RK85_RS05535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK85_RS05555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK85_RS05575	COG1073	alpha beta
RK85_RS05590	COG0438	transferase activity, transferring glycosyl groups
RK85_RS05605	COG3433	isochorismatase activity
RK85_RS05605	COG1535	isochorismatase
RK85_RS05610	COG1705	Flagellar rod assembly protein muramidase FlgJ
RK85_RS05610	COG3942	CHAP domain
RK85_RS05620	COG1482	cell wall glycoprotein biosynthetic process
RK85_RS05625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK85_RS05625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK85_RS05625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK85_RS05630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK85_RS05630	COG3711	transcriptional antiterminator
RK85_RS05650	COG1438	arginine binding
RK85_RS05695	COG1846	Transcriptional regulator
RK85_RS05705	COG1785	Belongs to the alkaline phosphatase family
RK85_RS05715	COG0745	RESPONSE REGULATOR receiver
RK85_RS05720	COG2205	protein histidine kinase activity
RK85_RS05725	COG1136	(ABC) transporter
RK85_RS05750	COG0386	Belongs to the glutathione peroxidase family
RK85_RS05760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RK85_RS05775	COG2851	Citrate transporter
RK85_RS05800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK85_RS05810	COG1510	regulation of RNA biosynthetic process
RK85_RS05820	COG1012	belongs to the aldehyde dehydrogenase family
RK85_RS05840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK85_RS05870	COG0531	amino acid
RK85_RS05885	COG3527	Alpha-acetolactate decarboxylase
RK85_RS05890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK85_RS05900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RK85_RS05940	COG0167	dihydroorotate dehydrogenase activity
RK85_RS05945	COG3001	Fructosamine kinase
RK85_RS05985	COG0596	Alpha beta hydrolase
RK85_RS06030	COG1309	transcriptional regulator
RK85_RS06055	COG2755	lipolytic protein G-D-S-L family
RK85_RS06055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RK85_RS06060	COG3942	CHAP domain
RK85_RS06090	COG0436	Aminotransferase
RK85_RS06135	COG2409	Drug exporters of the RND superfamily
RK85_RS06155	COG0542	response to heat
RK85_RS06160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RK85_RS06165	COG3425	synthase
RK85_RS06190	COG3942	CHAP domain
RK85_RS06200	COG0583	DNA-binding transcription factor activity
RK85_RS06215	COG0028	Belongs to the TPP enzyme family
RK85_RS06235	COG0657	acetylesterase activity
RK85_RS06240	COG0697	spore germination
RK85_RS06255	COG1760	l-serine dehydratase
RK85_RS06260	COG1760	l-serine dehydratase
RK85_RS06280	COG3764	Sortase (surface protein transpeptidase)
RK85_RS06290	COG1131	(ABC) transporter
RK85_RS06295	COG0561	phosphatase activity
RK85_RS06310	COG2514	catechol 2,3-dioxygenase activity
RK85_RS06320	COG1846	Transcriptional regulator
RK85_RS06325	COG0346	lactoylglutathione lyase activity
RK85_RS06330	COG0400	carboxylic ester hydrolase activity
RK85_RS06350	COG1131	(ABC) transporter
RK85_RS06365	COG1846	Transcriptional regulator
RK85_RS06370	COG2814	Major facilitator Superfamily
RK85_RS06380	COG0586	Pfam SNARE associated Golgi protein
RK85_RS06385	COG2271	Major facilitator Superfamily
RK85_RS06395	COG4876	unkown
RK85_RS06400	COG2357	RelA SpoT domain protein
RK85_RS06405	COG0789	Transcriptional regulator
RK85_RS06410	COG1802	Transcriptional regulator
RK85_RS06415	COG1070	Carbohydrate kinase
RK85_RS06435	COG4932	domain protein
RK85_RS06450	COG1846	Transcriptional regulator
RK85_RS06455	COG1846	Transcriptional regulator
RK85_RS06460	COG3583	domain protein
RK85_RS06495	COG0494	nUDIX hydrolase
RK85_RS06585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK85_RS06590	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RK85_RS06620	COG0747	negative chemotaxis
RK85_RS06625	COG0601	transmembrane transport
RK85_RS06630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK85_RS06635	COG0444	Belongs to the ABC transporter superfamily
RK85_RS06640	COG1124	(ABC) transporter
RK85_RS06655	COG0069	glutamate synthase activity
RK85_RS06660	COG4808	Protein conserved in bacteria
RK85_RS06680	COG1363	Peptidase, m42
RK85_RS06685	COG4619	ABC transporter
RK85_RS06690	COG0390	transport system, permease component
RK85_RS06695	COG2814	Major facilitator Superfamily
RK85_RS06700	COG2272	Belongs to the type-B carboxylesterase lipase family
RK85_RS06705	COG0531	amino acid
RK85_RS06715	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RK85_RS06735	COG1174	glycine betaine transport
RK85_RS06745	COG1174	glycine betaine transport
RK85_RS06755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK85_RS06770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RK85_RS06780	COG0531	amino acid
RK85_RS06795	COG1113	amino acid transport
RK85_RS06815	COG2814	Major facilitator Superfamily
RK85_RS06825	COG1929	Belongs to the glycerate kinase type-1 family
RK85_RS06850	COG1132	(ABC) transporter
RK85_RS06865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RK85_RS06870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RK85_RS06880	COG0156	8-amino-7-oxononanoate synthase activity
RK85_RS06930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RK85_RS06950	COG2814	Major facilitator Superfamily
RK85_RS06955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK85_RS06960	COG0765	amino acid transport
RK85_RS06965	COG1126	abc transporter atp-binding protein
RK85_RS07005	COG3443	Belongs to the bacterial solute-binding protein 9 family
RK85_RS07005	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK85_RS07020	COG2116	formate transmembrane transporter activity
RK85_RS07025	COG0454	-acetyltransferase
RK85_RS07035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RK85_RS07040	COG2146	nitrite reductase [NAD(P)H] activity
RK85_RS07050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RK85_RS07055	COG1140	nitrate reductase beta subunit
RK85_RS07065	COG2181	nitrate reductase activity
RK85_RS07085	COG0789	Transcriptional regulator
RK85_RS07125	COG3871	stress protein (general stress protein 26)
RK85_RS07140	COG1263	PTS System
RK85_RS07140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK85_RS07155	COG1511	domain protein
RK85_RS07180	COG0456	acetyltransferase
RK85_RS07185	COG0604	alcohol dehydrogenase
RK85_RS07205	COG1620	l-lactate permease
RK85_RS07275	COG2814	Major facilitator Superfamily
RK85_RS07285	COG1566	PFAM secretion protein HlyD family protein
RK85_RS07290	COG2814	Major facilitator Superfamily
RK85_RS07300	COG0657	acetylesterase activity
RK85_RS07315	COG0598	Magnesium transport protein CorA
RK85_RS07325	COG0786	glutamate:sodium symporter activity
RK85_RS07340	COG3152	Membrane
RK85_RS07345	COG4152	abc transporter atp-binding protein
RK85_RS07350	COG1668	transmembrane transport
RK85_RS07370	COG2258	MOSC domain
RK85_RS07395	COG0583	DNA-binding transcription factor activity
RK85_RS07410	COG1473	amidohydrolase
RK85_RS07415	COG1028	Short-chain dehydrogenase reductase Sdr
RK85_RS07435	COG1737	Transcriptional regulator
RK85_RS07440	COG1263	PTS System
RK85_RS07440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK85_RS07450	COG0385	Bile acid
RK85_RS07455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK85_RS07475	COG1113	amino acid transport
RK85_RS07550	COG3942	CHAP domain
RK85_RS07565	COG1757	Na H antiporter
RK85_RS07575	COG3942	CHAP domain
RK85_RS07640	COG4413	Urea transporter
RK85_RS07645	COG1960	acyl-CoA dehydrogenase activity
RK85_RS07660	COG1268	BioY protein
RK85_RS07675	COG0725	ABC transporter, periplasmic molybdate-binding protein
RK85_RS07680	COG4149	molybdate abc transporter
RK85_RS07685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RK85_RS07690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RK85_RS07710	COG1763	Mo-molybdopterin cofactor biosynthetic process
RK85_RS07785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK85_RS07825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RK85_RS07825	COG0551	DNA topoisomerase type I activity
RK85_RS07830	COG2252	PERMEase
RK85_RS07945	COG0201	protein transport
RK85_RS08030	COG0542	response to heat
RK85_RS08050	COG0028	Belongs to the TPP enzyme family
RK85_RS08055	COG3527	Alpha-acetolactate decarboxylase
RK85_RS08075	COG5492	domain, Protein
RK85_RS08085	COG0789	Transcriptional regulator
RK85_RS08090	COG0656	L-ascorbic acid biosynthetic process
RK85_RS08110	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RK85_RS08160	COG2130	NADP-dependent
RK85_RS08170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK85_RS08200	COG2814	Major facilitator Superfamily
RK85_RS08205	COG4264	IucA IucC family
RK85_RS08210	COG3457	Alanine racemase
RK85_RS08220	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK85_RS08225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK85_RS08230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK85_RS08245	COG1988	membrane-bound metal-dependent
RK85_RS08255	COG1272	protein, Hemolysin III
RK85_RS08270	COG2814	Major facilitator Superfamily
RK85_RS08275	COG0489	protein tyrosine kinase activity
RK85_RS08350	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RK85_RS08370	COG0246	Mannitol dehydrogenase
RK85_RS08380	COG3711	transcriptional antiterminator
RK85_RS08395	COG1119	ATPase activity
RK85_RS08400	COG0561	phosphatase activity
RK85_RS08435	COG0640	Transcriptional regulator
RK85_RS08440	COG0702	epimerase
RK85_RS08470	COG0783	Belongs to the Dps family
RK85_RS08475	COG0813	purine-nucleoside phosphorylase activity
RK85_RS08525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK85_RS08535	COG0504	CTP synthase activity
RK85_RS08565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RK85_RS08590	COG2890	protein-(glutamine-N5) methyltransferase activity
RK85_RS08595	COG0009	L-threonylcarbamoyladenylate synthase
RK85_RS08620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK85_RS08695	COG0629	single-stranded DNA binding
RK85_RS08705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RK85_RS08745	COG1418	mRNA catabolic process
RK85_RS08755	COG1937	Protein conserved in bacteria
RK85_RS08770	COG0772	Belongs to the SEDS family
RK85_RS08780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RK85_RS08790	COG0745	RESPONSE REGULATOR receiver
RK85_RS08795	COG2205	protein histidine kinase activity
RK85_RS08825	COG3428	Bacterial PH domain
RK85_RS08865	COG1366	Belongs to the anti-sigma-factor antagonist family
RK85_RS08875	COG1191	sigma factor activity
RK85_RS08880	COG2183	response to ionizing radiation
RK85_RS08935	COG0473	3-isopropylmalate dehydrogenase activity
RK85_RS08955	COG0028	Belongs to the TPP enzyme family
RK85_RS08970	COG0802	atpase or kinase
RK85_RS08975	COG1214	PFAM Peptidase M22, glycoprotease
RK85_RS08980	COG0456	acetyltransferase
RK85_RS08990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK85_RS09000	COG0488	(ABC) transporter
RK85_RS09010	COG2391	methyltransferase activity
RK85_RS09015	COG0425	Belongs to the sulfur carrier protein TusA family
RK85_RS09020	COG0004	ammonium transporteR
RK85_RS09025	COG1609	Transcriptional regulator
RK85_RS09030	COG1621	beta-fructofuranosidase activity
RK85_RS09035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK85_RS09110	COG3728	DNA packaging
RK85_RS09110	COG5484	DNA packaging
RK85_RS09130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK85_RS09135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK85_RS09140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RK85_RS09270	COG1484	DNA-dependent DNA replication
RK85_RS09385	COG4695	Portal protein
RK85_RS09440	COG0739	heme binding
RK85_RS09485	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK85_RS09485	COG1388	LysM domain
RK85_RS09500	COG0860	N-Acetylmuramoyl-L-alanine amidase
RK85_RS09500	COG1388	LysM domain
RK85_RS09560	COG1725	Transcriptional regulator
RK85_RS09575	COG1131	(ABC) transporter
RK85_RS09630	COG1012	belongs to the aldehyde dehydrogenase family
RK85_RS09645	COG1335	isochorismatase
RK85_RS09655	COG0471	metal ion transport
RK85_RS09665	COG0077	Prephenate dehydratase
RK85_RS09675	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RK85_RS09715	COG4496	protein, YerC YecD
RK85_RS09725	COG0210	DNA helicase
RK85_RS09735	COG4851	CamS sex pheromone cAM373 precursor
RK85_RS09865	COG2197	response regulator
RK85_RS09870	COG1295	ribonuclease BN
RK85_RS09890	COG2309	aminopeptidase activity
RK85_RS09895	COG1607	acyl-coa hydrolase
RK85_RS09900	COG0535	radical SAM domain protein
RK85_RS09930	COG1134	teichoic acid transport
RK85_RS09930	COG1388	LysM domain
RK85_RS09945	COG1988	membrane-bound metal-dependent
RK85_RS09970	COG4129	membrane
RK85_RS09980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RK85_RS09985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK85_RS10160	COG0765	amino acid transport
RK85_RS10165	COG1126	abc transporter atp-binding protein
RK85_RS10170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RK85_RS10210	COG0564	pseudouridine synthase activity
RK85_RS10215	COG4585	Histidine kinase
RK85_RS10215	COG2203	Gaf domain
RK85_RS10220	COG2197	response regulator
RK85_RS10250	COG0420	3'-5' exonuclease activity
RK85_RS10285	COG0537	adenosine 5'-monophosphoramidase activity
RK85_RS10290	COG1131	(ABC) transporter
RK85_RS10440	COG1131	(ABC) transporter
RK85_RS10620	COG1506	peptidase
RK85_RS10645	COG0656	L-ascorbic acid biosynthetic process
RK85_RS10670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RK85_RS10690	COG1595	DNA-templated transcription, initiation
RK85_RS10700	COG3266	domain, Protein
RK85_RS10700	COG4193	domain, Protein
RK85_RS10700	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK85_RS10725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK85_RS10725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK85_RS10760	COG2267	carboxylic ester hydrolase activity
RK85_RS10775	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RK85_RS10780	COG1242	4 iron, 4 sulfur cluster binding
RK85_RS10785	COG2814	Major facilitator Superfamily
RK85_RS10805	COG2081	HI0933 family
RK85_RS10810	COG2244	polysaccharide biosynthetic process
RK85_RS10815	COG1187	pseudouridine synthase activity
RK85_RS10840	COG0510	thiamine kinase activity
RK85_RS10850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK85_RS10860	COG1363	Peptidase, m42
RK85_RS10865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK85_RS10875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RK85_RS10880	COG1674	ftsk spoiiie
RK85_RS10905	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RK85_RS10905	COG1605	Chorismate mutase
RK85_RS10925	COG0454	-acetyltransferase
RK85_RS10930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK85_RS10935	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RK85_RS10945	COG5386	Cell surface protein
RK85_RS10965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK85_RS10970	COG0204	Acyl-transferase
RK85_RS10975	COG1263	PTS System
RK85_RS10975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK85_RS10990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK85_RS10995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RK85_RS11000	COG1764	response to oxidative stress
RK85_RS11005	COG0584	glycerophosphoryl diester phosphodiesterase
RK85_RS11025	COG1956	GAF domain-containing protein
RK85_RS11040	COG1104	cysteine desulfurase activity
RK85_RS11060	COG0827	DNA restriction-modification system
RK85_RS11100	COG4109	DRTGG domain
RK85_RS11110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RK85_RS11115	COG0587	DNA-directed DNA polymerase activity
RK85_RS11120	COG0281	malic enzyme
RK85_RS11150	COG1113	amino acid transport
RK85_RS11155	COG0372	Belongs to the citrate synthase family
RK85_RS11170	COG0745	RESPONSE REGULATOR receiver
RK85_RS11175	COG5002	protein histidine kinase activity
RK85_RS11185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK85_RS11185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK85_RS11215	COG1484	DNA-dependent DNA replication
RK85_RS11225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RK85_RS11230	COG0833	amino acid
RK85_RS11255	COG4112	unkown
RK85_RS11285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RK85_RS11290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK85_RS11325	COG2818	Glycosylase
RK85_RS11335	COG0285	dihydrofolate synthase activity
RK85_RS11345	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RK85_RS11390	COG2868	ribosomal protein
RK85_RS11430	COG1862	Preprotein translocase
RK85_RS11435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK85_RS11435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK85_RS11440	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RK85_RS11440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RK85_RS11470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RK85_RS11485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RK85_RS11490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RK85_RS11495	COG1959	2 iron, 2 sulfur cluster binding
RK85_RS11500	COG3237	CsbD-like
RK85_RS11510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK85_RS11515	COG1104	cysteine desulfurase activity
RK85_RS11530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RK85_RS11580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RK85_RS11585	COG1984	allophanate hydrolase subunit 2
RK85_RS11590	COG0511	ligase activity, forming carbon-carbon bonds
RK85_RS11595	COG0439	Biotin carboxylase
RK85_RS11605	COG1914	H( )-stimulated, divalent metal cation uptake system
RK85_RS11610	COG3177	Filamentation induced by cAMP protein fic
RK85_RS11630	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RK85_RS11635	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RK85_RS11645	COG1534	Rna-binding protein
RK85_RS11655	COG1713	HD superfamily hydrolase involved in NAD metabolism
RK85_RS11660	COG0799	negative regulation of ribosome biogenesis
RK85_RS11665	COG2226	methyltransferase
RK85_RS11675	COG2131	deaminase
RK85_RS11680	COG0658	competence protein
RK85_RS11680	COG2333	competence protein COMEC
RK85_RS11685	COG1466	dna polymerase III delta subunit
RK85_RS11705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RK85_RS11735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RK85_RS11740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RK85_RS11750	COG1030	water channel activity
RK85_RS11765	COG1702	phosphate starvation-inducible protein PhoH
RK85_RS11780	COG0295	cytidine deaminase activity
RK85_RS11785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RK85_RS11800	COG0517	IMP dehydrogenase activity
RK85_RS11820	COG2384	SAM-dependent methyltransferase
RK85_RS11830	COG0513	Belongs to the DEAD box helicase family
RK85_RS11840	COG1121	(ABC) transporter
RK85_RS11845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK85_RS11870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RK85_RS11880	COG4483	Protein conserved in bacteria
RK85_RS11885	COG1940	carbohydrate kinase activity
RK85_RS11890	COG0011	TIGRFAM Protein of
RK85_RS11895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK85_RS11900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RK85_RS11905	COG1459	type II secretion system
RK85_RS11910	COG4537	Required for transformation and DNA binding
RK85_RS11955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK85_RS11960	COG0095	Lipoate-protein ligase
RK85_RS11975	COG0006	proline dipeptidase activity
RK85_RS11985	COG0511	ligase activity, forming carbon-carbon bonds
RK85_RS11990	COG0439	Biotin carboxylase
RK85_RS11995	COG1302	Protein conserved in bacteria
RK85_RS12025	COG0497	DNA recombination
RK85_RS12030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK85_RS12035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RK85_RS12040	COG0022	dehydrogenase e1 component
RK85_RS12045	COG0508	dehydrogenase complex catalyzes the overall conversion of
RK85_RS12055	COG4129	membrane
RK85_RS12065	COG2195	Cleaves the N-terminal amino acid of tripeptides
RK85_RS12085	COG1609	Transcriptional regulator
RK85_RS12090	COG0366	Alpha amylase catalytic
RK85_RS12100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RK85_RS12115	COG4221	oxidoreductase activity
RK85_RS12125	COG0667	Aldo Keto reductase
RK85_RS12130	COG0494	nUDIX hydrolase
RK85_RS12135	COG0735	belongs to the Fur family
RK85_RS12160	COG1187	pseudouridine synthase activity
RK85_RS12165	COG0745	RESPONSE REGULATOR receiver
RK85_RS12170	COG5002	protein histidine kinase activity
RK85_RS12215	COG1141	Ferredoxin
RK85_RS12225	COG0514	ATP-dependent DNA helicase (RecQ)
RK85_RS12240	COG0492	ferredoxin-NADP+ reductase activity
RK85_RS12305	COG0142	geranyltranstransferase activity
RK85_RS12325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RK85_RS12340	COG5582	Belongs to the UPF0302 family
RK85_RS12345	COG4347	Protein of unknown function (DUF1405)
RK85_RS12350	COG2738	Putative neutral zinc metallopeptidase
RK85_RS12355	COG1694	Mazg nucleotide pyrophosphohydrolase
RK85_RS12360	COG0438	transferase activity, transferring glycosyl groups
RK85_RS12385	COG3935	DnaD domain protein
RK85_RS12390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RK85_RS12400	COG4499	WXG100 protein secretion system (Wss), protein YukC
RK85_RS12400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RK85_RS12440	COG0116	Belongs to the methyltransferase superfamily
RK85_RS12455	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RK85_RS12460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK85_RS12465	COG0686	Belongs to the AlaDH PNT family
RK85_RS12475	COG0531	amino acid
RK85_RS12500	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RK85_RS12515	COG1413	lyase activity
RK85_RS12575	COG0671	phosphoesterase, PA-phosphatase related
RK85_RS12620	COG0714	Associated with various cellular activities
RK85_RS12625	COG4548	von Willebrand factor, type A
RK85_RS12705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RK85_RS12710	COG0527	aspartate kinase activity
RK85_RS12715	COG0488	(ABC) transporter
RK85_RS12735	COG0573	inorganic phosphate transmembrane transporter activity
RK85_RS12740	COG0581	inorganic phosphate transmembrane transporter activity
RK85_RS12750	COG0704	Plays a role in the regulation of phosphate uptake
RK85_RS12795	COG0561	phosphatase activity
RK85_RS12835	COG0512	Glutamine amidotransferase of anthranilate synthase
RK85_RS12840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK85_RS12845	COG1363	Peptidase, m42
RK85_RS12850	COG0287	Prephenate dehydrogenase
RK85_RS12855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RK85_RS12875	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RK85_RS12875	COG0392	lysyltransferase activity
RK85_RS12880	COG0628	permease
RK85_RS12895	COG1115	amino acid carrier protein
RK85_RS12905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RK85_RS12935	COG0824	Thioesterase
RK85_RS12950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK85_RS12970	COG4846	Membrane protein involved in cytochrome C biogenesis
RK85_RS13005	COG2340	Cysteine-rich secretory protein family
RK85_RS13035	COG0833	amino acid
RK85_RS13060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RK85_RS13065	COG0460	homoserine dehydrogenase
RK85_RS13070	COG0527	aspartate kinase activity
RK85_RS13085	COG1525	nuclease
RK85_RS13095	COG2197	response regulator
RK85_RS13110	COG1131	(ABC) transporter
RK85_RS13230	COG0789	Transcriptional regulator
RK85_RS13235	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RK85_RS13250	COG1923	regulation of RNA biosynthetic process
RK85_RS13275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RK85_RS13280	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RK85_RS13290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK85_RS13315	COG1013	pyruvate-flavodoxin oxidoreductase activity
RK85_RS13320	COG0674	pyruvate-flavodoxin oxidoreductase activity
RK85_RS13320	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RK85_RS13325	COG1692	metallophosphoesterase
RK85_RS13345	COG1058	Belongs to the CinA family
RK85_RS13345	COG1546	Belongs to the CinA family
RK85_RS13365	COG0300	oxidoreductase activity
RK85_RS13370	COG0612	Peptidase, M16
RK85_RS13375	COG0612	Peptidase, M16
RK85_RS13380	COG2188	Transcriptional regulator
RK85_RS13410	COG0196	riboflavin kinase activity
RK85_RS13435	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RK85_RS13440	COG0195	Participates in both transcription termination and antitermination
RK85_RS13540	COG0758	DNA mediated transformation
RK85_RS13600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RK85_RS13610	COG0552	protein localization to endoplasmic reticulum
RK85_RS13615	COG1196	nuclear chromosome segregation
RK85_RS13655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RK85_RS13665	COG1302	Protein conserved in bacteria
RK85_RS13680	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK85_RS13695	COG0631	protein serine/threonine phosphatase activity
RK85_RS13705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RK85_RS13705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RK85_RS13720	COG2314	TM2 domain
RK85_RS13730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RK85_RS13735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RK85_RS13750	COG1293	RNA-binding protein homologous to eukaryotic snRNP
RK85_RS13795	COG2233	PERMEase
RK85_RS13805	COG0564	pseudouridine synthase activity
RK85_RS13825	COG2514	catechol 2,3-dioxygenase activity
RK85_RS13835	COG3599	regulation of cell shape
RK85_RS13840	COG2302	S4 RNA-binding domain
RK85_RS13845	COG0762	integral membrane protein
RK85_RS13855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RK85_RS13870	COG0849	cell division
RK85_RS13875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RK85_RS13895	COG4839	cell division protein FtsL
RK85_RS13920	COG1011	Hydrolase
RK85_RS13955	COG1288	antiporter activity
RK85_RS14070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RK85_RS14075	COG1053	succinate dehydrogenase
RK85_RS14080	COG2009	succinate dehydrogenase
RK85_RS14105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RK85_RS14105	COG1796	DNA polymerase
RK85_RS14115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
RK85_RS14140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RK85_RS14155	COG4509	Sortase family
RK85_RS14165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK85_RS14220	COG0742	ribosomal rna small subunit methyltransferase
RK85_RS14240	COG3679	Belongs to the UPF0342 family