locus-tag	class	description
RK98_RS00035	COG0281	malic enzyme
RK98_RS00045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RK98_RS00050	COG4109	DRTGG domain
RK98_RS00090	COG0827	DNA restriction-modification system
RK98_RS00100	COG0730	response to heat
RK98_RS00110	COG1104	cysteine desulfurase activity
RK98_RS00125	COG1956	GAF domain-containing protein
RK98_RS00150	COG0584	glycerophosphoryl diester phosphodiesterase
RK98_RS00155	COG1764	response to oxidative stress
RK98_RS00160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RK98_RS00165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK98_RS00180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK98_RS00180	COG1263	PTS System
RK98_RS00185	COG0204	Acyl-transferase
RK98_RS00190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK98_RS00225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK98_RS00230	COG0454	-acetyltransferase
RK98_RS00250	COG1605	Chorismate mutase
RK98_RS00250	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RK98_RS00275	COG1674	ftsk spoiiie
RK98_RS00280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RK98_RS00290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK98_RS00295	COG1363	Peptidase, m42
RK98_RS00305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK98_RS00315	COG0510	thiamine kinase activity
RK98_RS00335	COG1187	pseudouridine synthase activity
RK98_RS00340	COG2244	polysaccharide biosynthetic process
RK98_RS00365	COG2814	Major facilitator Superfamily
RK98_RS00370	COG1242	4 iron, 4 sulfur cluster binding
RK98_RS00375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RK98_RS00385	COG2267	carboxylic ester hydrolase activity
RK98_RS00415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK98_RS00415	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK98_RS00435	COG4193	domain, Protein
RK98_RS00435	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK98_RS00435	COG3266	domain, Protein
RK98_RS00465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RK98_RS00490	COG0656	L-ascorbic acid biosynthetic process
RK98_RS00510	COG1506	peptidase
RK98_RS00515	COG2816	NAD+ diphosphatase activity
RK98_RS00775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
RK98_RS00805	COG1131	(ABC) transporter
RK98_RS00810	COG0537	adenosine 5'-monophosphoramidase activity
RK98_RS00840	COG0420	3'-5' exonuclease activity
RK98_RS00870	COG2197	response regulator
RK98_RS00875	COG4585	Histidine kinase
RK98_RS00875	COG2203	Gaf domain
RK98_RS00880	COG0564	pseudouridine synthase activity
RK98_RS00910	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RK98_RS00915	COG1126	abc transporter atp-binding protein
RK98_RS00920	COG0765	amino acid transport
RK98_RS01090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK98_RS01095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RK98_RS01105	COG4129	membrane
RK98_RS01130	COG1988	membrane-bound metal-dependent
RK98_RS01145	COG1134	teichoic acid transport
RK98_RS01145	COG1388	LysM domain
RK98_RS01175	COG0535	radical SAM domain protein
RK98_RS01180	COG1607	acyl-coa hydrolase
RK98_RS01185	COG2309	aminopeptidase activity
RK98_RS01205	COG1295	ribonuclease BN
RK98_RS01330	COG4851	CamS sex pheromone cAM373 precursor
RK98_RS01350	COG4496	protein, YerC YecD
RK98_RS01390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RK98_RS01400	COG0077	Prephenate dehydratase
RK98_RS01410	COG0471	metal ion transport
RK98_RS01420	COG1335	isochorismatase
RK98_RS01435	COG1012	belongs to the aldehyde dehydrogenase family
RK98_RS01490	COG1131	(ABC) transporter
RK98_RS01505	COG1725	Transcriptional regulator
RK98_RS01560	COG1388	LysM domain
RK98_RS01560	COG0860	N-Acetylmuramoyl-L-alanine amidase
RK98_RS01585	COG1388	LysM domain
RK98_RS01585	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK98_RS01635	COG0739	heme binding
RK98_RS01685	COG0740	serine-type endopeptidase activity
RK98_RS01855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RK98_RS01900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK98_RS01930	COG5484	DNA packaging
RK98_RS01930	COG3728	DNA packaging
RK98_RS02035	COG0557	exoribonuclease II activity
RK98_RS02040	COG1647	Serine aminopeptidase, S33
RK98_RS02045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RK98_RS02120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RK98_RS02180	COG1388	LysM domain
RK98_RS02180	COG3942	CHAP domain
RK98_RS02210	COG1040	competence protein
RK98_RS02215	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RK98_RS02225	COG1739	Uncharacterized protein family UPF0029
RK98_RS02230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RK98_RS02285	COG4607	ABC-type enterochelin transport system periplasmic component
RK98_RS02290	COG4604	ABC transporter, ATP-binding protein
RK98_RS02295	COG4605	iron ion homeostasis
RK98_RS02300	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK98_RS02310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK98_RS02315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK98_RS02345	COG3104	oligopeptide transport
RK98_RS02380	COG1174	glycine betaine transport
RK98_RS02385	COG0517	IMP dehydrogenase activity
RK98_RS02385	COG1125	glycine betaine transport
RK98_RS02390	COG0514	ATP-dependent DNA helicase (RecQ)
RK98_RS02395	COG0488	(ABC) transporter
RK98_RS02425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK98_RS02430	COG0512	Glutamine amidotransferase of anthranilate synthase
RK98_RS02430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RK98_RS02440	COG0720	synthase
RK98_RS02475	COG0463	Glycosyl transferase, family 2
RK98_RS02480	COG0656	L-ascorbic acid biosynthetic process
RK98_RS02485	COG1253	flavin adenine dinucleotide binding
RK98_RS02490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RK98_RS02495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK98_RS02495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK98_RS02495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK98_RS02500	COG1105	Belongs to the carbohydrate kinase PfkB family
RK98_RS02505	COG1349	DNA-binding transcription factor activity
RK98_RS02510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RK98_RS02540	COG0415	Belongs to the DNA photolyase family
RK98_RS02545	COG0471	metal ion transport
RK98_RS02555	COG4989	oxidoreductase activity
RK98_RS02560	COG0523	cobalamin synthesis protein
RK98_RS02570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RK98_RS02575	COG4988	ABC transporter
RK98_RS02595	COG1611	Belongs to the LOG family
RK98_RS02625	COG2839	Protein conserved in bacteria
RK98_RS02630	COG2814	Major facilitator Superfamily
RK98_RS02635	COG0583	DNA-binding transcription factor activity
RK98_RS02665	COG1917	Cupin 2, conserved barrel domain protein
RK98_RS02665	COG4977	sequence-specific DNA binding
RK98_RS02675	COG1388	LysM domain
RK98_RS02675	COG3942	CHAP domain
RK98_RS02680	COG0306	phosphate transporter
RK98_RS02685	COG1392	Phosphate transport regulator
RK98_RS02690	COG0577	efflux transmembrane transporter activity
RK98_RS02695	COG1136	(ABC) transporter
RK98_RS02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK98_RS02735	COG3949	Membrane
RK98_RS02745	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RK98_RS02755	COG2376	Dihydroxyacetone kinase
RK98_RS02760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK98_RS02765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK98_RS02770	COG1120	ATPase activity
RK98_RS02775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RK98_RS02785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK98_RS02790	COG1132	(ABC) transporter
RK98_RS02795	COG1686	Belongs to the peptidase S11 family
RK98_RS02800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RK98_RS02810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK98_RS02815	COG1682	transport, permease protein
RK98_RS02825	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RK98_RS02835	COG1321	iron dependent repressor
RK98_RS02840	COG1121	(ABC) transporter
RK98_RS02845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK98_RS02850	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK98_RS02905	COG4974	Belongs to the 'phage' integrase family
RK98_RS02955	COG4139	cobalamin transport
RK98_RS02960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK98_RS02995	COG1078	dGTPase activity
RK98_RS03005	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK98_RS03015	COG0667	Aldo Keto reductase
RK98_RS03050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK98_RS03070	COG0083	homoserine kinase activity
RK98_RS03075	COG0095	Lipoate-protein ligase
RK98_RS03175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RK98_RS03190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RK98_RS03235	COG0561	phosphatase activity
RK98_RS03245	COG1428	Deoxynucleoside kinase
RK98_RS03250	COG1428	Deoxynucleoside kinase
RK98_RS03255	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RK98_RS03285	COG1473	amidohydrolase
RK98_RS03325	COG2813	Specifically methylates the guanine in position
RK98_RS03385	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RK98_RS03410	COG4956	integral membrane protein (PIN domain superfamily)
RK98_RS03415	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RK98_RS03430	COG3880	PFAM UvrB UvrC protein
RK98_RS03440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK98_RS03455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK98_RS03535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RK98_RS03560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RK98_RS03575	COG1098	S1 RNA binding domain
RK98_RS03585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RK98_RS03590	COG3956	TIGRFAM MazG family protein
RK98_RS03595	COG2244	polysaccharide biosynthetic process
RK98_RS03640	COG0251	oxidation-reduction process
RK98_RS03645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RK98_RS03655	COG4466	Protein conserved in bacteria
RK98_RS03665	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK98_RS03670	COG0084	hydrolase, TatD family'
RK98_RS03680	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RK98_RS03690	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RK98_RS03700	COG1774	PSP1 C-terminal conserved region
RK98_RS03705	COG0470	DNA polymerase III
RK98_RS03710	COG3870	Protein conserved in bacteria
RK98_RS03720	COG1982	Orn Lys Arg decarboxylase major
RK98_RS03760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RK98_RS03780	COG2188	Transcriptional regulator
RK98_RS03785	COG0366	Alpha amylase catalytic
RK98_RS03790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK98_RS03790	COG1263	PTS System
RK98_RS03800	COG0493	'glutamate synthase
RK98_RS03805	COG0069	glutamate synthase activity
RK98_RS03805	COG0067	glutamate synthase
RK98_RS03805	COG0070	glutamate synthase
RK98_RS03810	COG0583	DNA-binding transcription factor activity
RK98_RS03845	COG1464	Belongs to the NlpA lipoprotein family
RK98_RS03850	COG2011	ABC-type metal ion transport system permease component
RK98_RS03860	COG0626	cystathionine gamma-synthase activity
RK98_RS03865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RK98_RS03870	COG0733	neurotransmitter:sodium symporter activity
RK98_RS03875	COG1647	Serine aminopeptidase, S33
RK98_RS03890	COG5609	conserved protein (DUF2294)
RK98_RS03900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RK98_RS03925	COG0523	cobalamin synthesis protein
RK98_RS04080	COG3759	membrane
RK98_RS04115	COG3328	transposase activity
RK98_RS04145	COG1674	ftsk spoiiie
RK98_RS04150	COG2946	Replication initiation factor
RK98_RS04195	COG0791	NLP P60 protein
RK98_RS04195	COG0741	lytic transglycosylase activity
RK98_RS04255	COG0582	viral genome integration into host DNA
RK98_RS04270	COG2233	PERMEase
RK98_RS04310	COG1823	symporter activity
RK98_RS04415	COG0012	GTP binding
RK98_RS04420	COG4481	Protein conserved in bacteria
RK98_RS04425	COG0668	transmembrane transport
RK98_RS04430	COG1475	DNA binding
RK98_RS04440	COG0626	cystathionine gamma-synthase activity
RK98_RS04445	COG0626	cystathionine gamma-synthase activity
RK98_RS04450	COG0646	methionine synthase
RK98_RS04450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RK98_RS04480	COG1131	(ABC) transporter
RK98_RS04490	COG1476	TRANSCRIPTIONal
RK98_RS04500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RK98_RS04505	COG0805	protein transport
RK98_RS04510	COG0672	)-iron permease
RK98_RS04520	COG2822	iron ion transport
RK98_RS04525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK98_RS04540	COG0431	NADPH-dependent FMN reductase
RK98_RS04545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK98_RS04550	COG0346	lactoylglutathione lyase activity
RK98_RS04555	COG2271	Major facilitator Superfamily
RK98_RS04560	COG2271	Major facilitator Superfamily
RK98_RS04585	COG3711	transcriptional antiterminator
RK98_RS04590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK98_RS04600	COG3037	sugar-specific permease SgaT UlaA
RK98_RS04630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK98_RS04655	COG3314	Sporulation integral membrane protein YlbJ
RK98_RS04680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RK98_RS04685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK98_RS04715	COG0577	efflux transmembrane transporter activity
RK98_RS04725	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
RK98_RS04735	COG1114	Component of the transport system for branched-chain amino acids
RK98_RS04855	COG3942	CHAP domain
RK98_RS04855	COG1388	LysM domain
RK98_RS04875	COG1131	(ABC) transporter
RK98_RS04930	COG2226	methyltransferase
RK98_RS04940	COG2723	6-phospho-beta-galactosidase activity
RK98_RS04945	COG2190	(PTS) system
RK98_RS04945	COG1263	PTS System
RK98_RS04945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK98_RS04955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK98_RS04990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK98_RS04995	COG1063	alcohol dehydrogenase
RK98_RS05005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK98_RS05010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK98_RS05015	COG1063	alcohol dehydrogenase
RK98_RS05025	COG1063	alcohol dehydrogenase
RK98_RS05035	COG1063	alcohol dehydrogenase
RK98_RS05040	COG3775	system Galactitol-specific IIC component
RK98_RS05045	COG3414	Phosphotransferase system galactitol-specific IIB component
RK98_RS05065	COG1957	nucleoside hydrolase
RK98_RS05070	COG2190	(PTS) system
RK98_RS05070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK98_RS05070	COG1263	PTS System
RK98_RS05105	COG3189	MarR family transcriptional regulator
RK98_RS05110	COG0747	negative chemotaxis
RK98_RS05125	COG0318	PFAM AMP-dependent synthetase and ligase
RK98_RS05130	COG1960	acyl-CoA dehydrogenase activity
RK98_RS05140	COG0183	Belongs to the thiolase family
RK98_RS05195	COG1755	Isoprenylcysteine carboxyl methyltransferase
RK98_RS05205	COG0673	inositol 2-dehydrogenase activity
RK98_RS05210	COG0673	inositol 2-dehydrogenase activity
RK98_RS05215	COG3833	ABC-type maltose transport systems, permease component
RK98_RS05220	COG1175	transmembrane transport
RK98_RS05230	COG3842	ATPase activity
RK98_RS05250	COG0405	Gamma-glutamyltransferase
RK98_RS05260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK98_RS05265	COG0601	transmembrane transport
RK98_RS05280	COG1131	(ABC) transporter
RK98_RS05300	COG0577	efflux transmembrane transporter activity
RK98_RS05300	COG1136	(ABC) transporter
RK98_RS05305	COG1136	(ABC) transporter
RK98_RS05330	COG1737	Transcriptional regulator
RK98_RS05360	COG3961	Belongs to the TPP enzyme family
RK98_RS05365	COG1335	isochorismatase
RK98_RS05370	COG1114	Component of the transport system for branched-chain amino acids
RK98_RS05420	COG5609	conserved protein (DUF2294)
RK98_RS05425	COG1960	acyl-CoA dehydrogenase activity
RK98_RS05430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RK98_RS05465	COG2832	Protein of unknown function (DUF454)
RK98_RS05475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK98_RS05480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RK98_RS05490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK98_RS05520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK98_RS05530	COG1086	Polysaccharide biosynthesis protein
RK98_RS05555	COG1012	belongs to the aldehyde dehydrogenase family
RK98_RS05555	COG1454	alcohol dehydrogenase
RK98_RS05570	COG0737	Belongs to the 5'-nucleotidase family
RK98_RS05590	COG3639	organic phosphonate transmembrane transporter activity
RK98_RS05610	COG2814	Major facilitator Superfamily
RK98_RS05615	COG0813	purine-nucleoside phosphorylase activity
RK98_RS05650	COG0438	transferase activity, transferring glycosyl groups
RK98_RS05655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK98_RS05660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK98_RS05685	COG1475	DNA binding
RK98_RS05690	COG0019	diaminopimelate decarboxylase activity
RK98_RS05700	COG4264	IucA IucC family
RK98_RS05705	COG4264	IucA IucC family
RK98_RS05710	COG2814	Major facilitator Superfamily
RK98_RS05715	COG4264	IucA IucC family
RK98_RS05720	COG2423	ornithine cyclodeaminase activity
RK98_RS05730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK98_RS05735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK98_RS05740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK98_RS05760	COG1620	l-lactate permease
RK98_RS05775	COG0697	spore germination
RK98_RS05780	COG4716	Myosin-crossreactive antigen
RK98_RS05785	COG1283	sodium-dependent phosphate transmembrane transporter activity
RK98_RS05795	COG1473	amidohydrolase
RK98_RS05830	COG0823	Involved in the tonB-independent uptake of proteins
RK98_RS05880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK98_RS05885	COG2210	Belongs to the sulfur carrier protein TusA family
RK98_RS05890	COG1937	Protein conserved in bacteria
RK98_RS05895	COG0730	response to heat
RK98_RS05975	COG0745	RESPONSE REGULATOR receiver
RK98_RS06030	COG2003	Belongs to the UPF0758 family
RK98_RS06065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RK98_RS06075	COG0730	response to heat
RK98_RS06080	COG1937	Protein conserved in bacteria
RK98_RS06085	COG2210	Belongs to the sulfur carrier protein TusA family
RK98_RS06090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK98_RS06100	COG1940	carbohydrate kinase activity
RK98_RS06100	COG1846	Transcriptional regulator
RK98_RS06125	COG2030	dehydratase
RK98_RS06130	COG0584	glycerophosphoryl diester phosphodiesterase
RK98_RS06140	COG3425	synthase
RK98_RS06195	COG0737	Belongs to the 5'-nucleotidase family
RK98_RS06200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RK98_RS06210	COG4863	YycH protein
RK98_RS06245	COG0305	Participates in initiation and elongation during chromosome replication
RK98_RS06255	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RK98_RS06265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RK98_RS06295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RK98_RS06315	COG2501	S4 domain
RK98_RS06355	COG1475	DNA binding
RK98_RS06380	COG1278	Cold shock
RK98_RS06390	COG0577	efflux transmembrane transporter activity
RK98_RS06395	COG1136	(ABC) transporter
RK98_RS06410	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RK98_RS06420	COG2962	Rard protein
RK98_RS06510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RK98_RS06605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK98_RS06625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK98_RS06645	COG1073	alpha beta
RK98_RS06660	COG0438	transferase activity, transferring glycosyl groups
RK98_RS06675	COG3433	isochorismatase activity
RK98_RS06675	COG1535	isochorismatase
RK98_RS06680	COG3942	CHAP domain
RK98_RS06680	COG1705	Flagellar rod assembly protein muramidase FlgJ
RK98_RS06690	COG1482	cell wall glycoprotein biosynthetic process
RK98_RS06695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK98_RS06695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK98_RS06695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK98_RS06700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK98_RS06700	COG3711	transcriptional antiterminator
RK98_RS06720	COG1438	arginine binding
RK98_RS06765	COG1846	Transcriptional regulator
RK98_RS06775	COG1785	Belongs to the alkaline phosphatase family
RK98_RS06785	COG0745	RESPONSE REGULATOR receiver
RK98_RS06790	COG2205	protein histidine kinase activity
RK98_RS06795	COG1136	(ABC) transporter
RK98_RS06820	COG0386	Belongs to the glutathione peroxidase family
RK98_RS06830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RK98_RS06845	COG2851	Citrate transporter
RK98_RS06870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK98_RS06875	COG1510	regulation of RNA biosynthetic process
RK98_RS06885	COG1012	belongs to the aldehyde dehydrogenase family
RK98_RS06905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK98_RS06935	COG0531	amino acid
RK98_RS06950	COG3527	Alpha-acetolactate decarboxylase
RK98_RS06955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK98_RS07015	COG0167	dihydroorotate dehydrogenase activity
RK98_RS07020	COG3001	Fructosamine kinase
RK98_RS07130	COG2755	lipolytic protein G-D-S-L family
RK98_RS07130	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RK98_RS07135	COG3942	CHAP domain
RK98_RS07165	COG0436	Aminotransferase
RK98_RS07210	COG2409	Drug exporters of the RND superfamily
RK98_RS07235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RK98_RS07240	COG3425	synthase
RK98_RS07250	COG3942	CHAP domain
RK98_RS07260	COG0583	DNA-binding transcription factor activity
RK98_RS07275	COG0028	Belongs to the TPP enzyme family
RK98_RS07295	COG0657	acetylesterase activity
RK98_RS07300	COG0697	spore germination
RK98_RS07315	COG1760	l-serine dehydratase
RK98_RS07320	COG1760	l-serine dehydratase
RK98_RS07340	COG3764	Sortase (surface protein transpeptidase)
RK98_RS07350	COG1131	(ABC) transporter
RK98_RS07355	COG0561	phosphatase activity
RK98_RS07370	COG2514	catechol 2,3-dioxygenase activity
RK98_RS07380	COG1846	Transcriptional regulator
RK98_RS07385	COG0346	lactoylglutathione lyase activity
RK98_RS07390	COG0400	carboxylic ester hydrolase activity
RK98_RS07410	COG1131	(ABC) transporter
RK98_RS07430	COG0586	Pfam SNARE associated Golgi protein
RK98_RS07435	COG2271	Major facilitator Superfamily
RK98_RS07445	COG4876	unkown
RK98_RS07450	COG2357	RelA SpoT domain protein
RK98_RS07455	COG0789	Transcriptional regulator
RK98_RS07460	COG1802	Transcriptional regulator
RK98_RS07465	COG1070	Carbohydrate kinase
RK98_RS07505	COG1846	Transcriptional regulator
RK98_RS07550	COG0494	nUDIX hydrolase
RK98_RS07650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK98_RS07655	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RK98_RS07660	COG1028	Short-chain dehydrogenase reductase Sdr
RK98_RS07665	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RK98_RS07720	COG0069	glutamate synthase activity
RK98_RS07725	COG4808	Protein conserved in bacteria
RK98_RS07745	COG1363	Peptidase, m42
RK98_RS07750	COG4619	ABC transporter
RK98_RS07755	COG0390	transport system, permease component
RK98_RS07760	COG2814	Major facilitator Superfamily
RK98_RS07765	COG2272	Belongs to the type-B carboxylesterase lipase family
RK98_RS07770	COG0531	amino acid
RK98_RS07780	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RK98_RS07800	COG1174	glycine betaine transport
RK98_RS07810	COG1174	glycine betaine transport
RK98_RS07820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK98_RS07845	COG0531	amino acid
RK98_RS07860	COG1113	amino acid transport
RK98_RS07880	COG2814	Major facilitator Superfamily
RK98_RS07890	COG1929	Belongs to the glycerate kinase type-1 family
RK98_RS07910	COG1132	(ABC) transporter
RK98_RS07910	COG2375	cellular response to nickel ion
RK98_RS07915	COG1132	(ABC) transporter
RK98_RS07930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RK98_RS07935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RK98_RS07945	COG0156	8-amino-7-oxononanoate synthase activity
RK98_RS07995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RK98_RS08015	COG2814	Major facilitator Superfamily
RK98_RS08020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK98_RS08025	COG0765	amino acid transport
RK98_RS08030	COG1126	abc transporter atp-binding protein
RK98_RS08070	COG3443	Belongs to the bacterial solute-binding protein 9 family
RK98_RS08070	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK98_RS08085	COG2116	formate transmembrane transporter activity
RK98_RS08090	COG0454	-acetyltransferase
RK98_RS08100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RK98_RS08105	COG2146	nitrite reductase [NAD(P)H] activity
RK98_RS08115	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RK98_RS08120	COG1140	nitrate reductase beta subunit
RK98_RS08130	COG2181	nitrate reductase activity
RK98_RS08150	COG0789	Transcriptional regulator
RK98_RS08190	COG3871	stress protein (general stress protein 26)
RK98_RS08215	COG1263	PTS System
RK98_RS08215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK98_RS08230	COG1511	domain protein
RK98_RS08260	COG0604	alcohol dehydrogenase
RK98_RS08280	COG1620	l-lactate permease
RK98_RS08345	COG2814	Major facilitator Superfamily
RK98_RS08355	COG1566	PFAM secretion protein HlyD family protein
RK98_RS08360	COG2814	Major facilitator Superfamily
RK98_RS08370	COG0657	acetylesterase activity
RK98_RS08385	COG0598	Magnesium transport protein CorA
RK98_RS08395	COG0786	glutamate:sodium symporter activity
RK98_RS08415	COG3152	Membrane
RK98_RS08420	COG4152	abc transporter atp-binding protein
RK98_RS08425	COG1668	transmembrane transport
RK98_RS08445	COG2258	MOSC domain
RK98_RS08470	COG0583	DNA-binding transcription factor activity
RK98_RS08485	COG1473	amidohydrolase
RK98_RS08490	COG1028	Short-chain dehydrogenase reductase Sdr
RK98_RS08510	COG1737	Transcriptional regulator
RK98_RS08515	COG1263	PTS System
RK98_RS08515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK98_RS08525	COG0385	Bile acid
RK98_RS08530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK98_RS08550	COG1113	amino acid transport
RK98_RS08620	COG3942	CHAP domain
RK98_RS08635	COG1757	Na H antiporter
RK98_RS08645	COG3942	CHAP domain
RK98_RS08710	COG4413	Urea transporter
RK98_RS08715	COG1960	acyl-CoA dehydrogenase activity
RK98_RS08730	COG1268	BioY protein
RK98_RS08745	COG0725	ABC transporter, periplasmic molybdate-binding protein
RK98_RS08750	COG4149	molybdate abc transporter
RK98_RS08755	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RK98_RS08760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RK98_RS08780	COG1763	Mo-molybdopterin cofactor biosynthetic process
RK98_RS08850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK98_RS08900	COG2252	PERMEase
RK98_RS09015	COG0201	protein transport
RK98_RS09130	COG0028	Belongs to the TPP enzyme family
RK98_RS09135	COG3527	Alpha-acetolactate decarboxylase
RK98_RS09155	COG5492	domain, Protein
RK98_RS09165	COG0789	Transcriptional regulator
RK98_RS09170	COG0656	L-ascorbic acid biosynthetic process
RK98_RS09235	COG2130	NADP-dependent
RK98_RS09245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK98_RS09270	COG2814	Major facilitator Superfamily
RK98_RS09275	COG4264	IucA IucC family
RK98_RS09280	COG3457	Alanine racemase
RK98_RS09290	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK98_RS09295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK98_RS09300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK98_RS09305	COG3314	Sporulation integral membrane protein YlbJ
RK98_RS09315	COG1988	membrane-bound metal-dependent
RK98_RS09325	COG1272	protein, Hemolysin III
RK98_RS09340	COG2814	Major facilitator Superfamily
RK98_RS09345	COG0489	protein tyrosine kinase activity
RK98_RS09405	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RK98_RS09435	COG3711	transcriptional antiterminator
RK98_RS09450	COG1119	ATPase activity
RK98_RS09455	COG0561	phosphatase activity
RK98_RS09490	COG0640	Transcriptional regulator
RK98_RS09495	COG0702	epimerase
RK98_RS09500	COG1482	cell wall glycoprotein biosynthetic process
RK98_RS09520	COG0783	Belongs to the Dps family
RK98_RS09525	COG0813	purine-nucleoside phosphorylase activity
RK98_RS09575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK98_RS09615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RK98_RS09640	COG2890	protein-(glutamine-N5) methyltransferase activity
RK98_RS09645	COG0009	L-threonylcarbamoyladenylate synthase
RK98_RS09670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK98_RS09745	COG0629	single-stranded DNA binding
RK98_RS09795	COG1418	mRNA catabolic process
RK98_RS09805	COG1937	Protein conserved in bacteria
RK98_RS09820	COG0772	Belongs to the SEDS family
RK98_RS09830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RK98_RS09850	COG0745	RESPONSE REGULATOR receiver
RK98_RS09855	COG2205	protein histidine kinase activity
RK98_RS09885	COG3428	Bacterial PH domain
RK98_RS09920	COG2208	phosphoserine phosphatase activity
RK98_RS09925	COG1366	Belongs to the anti-sigma-factor antagonist family
RK98_RS09935	COG1191	sigma factor activity
RK98_RS09940	COG2183	response to ionizing radiation
RK98_RS10015	COG0028	Belongs to the TPP enzyme family
RK98_RS10030	COG0802	atpase or kinase
RK98_RS10035	COG1214	PFAM Peptidase M22, glycoprotease
RK98_RS10040	COG0456	acetyltransferase
RK98_RS10050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK98_RS10060	COG0488	(ABC) transporter
RK98_RS10070	COG2391	methyltransferase activity
RK98_RS10075	COG0425	Belongs to the sulfur carrier protein TusA family
RK98_RS10080	COG0004	ammonium transporteR
RK98_RS10085	COG1609	Transcriptional regulator
RK98_RS10090	COG1621	beta-fructofuranosidase activity
RK98_RS10095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK98_RS10160	COG0582	viral genome integration into host DNA
RK98_RS10240	COG5484	DNA packaging
RK98_RS10240	COG3728	DNA packaging
RK98_RS10260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK98_RS10265	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RK98_RS10330	COG1278	Cold shock
RK98_RS10370	COG0406	alpha-ribazole phosphatase activity
RK98_RS10375	COG1279	arginine transmembrane transporter activity
RK98_RS10400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK98_RS10405	COG1393	Belongs to the ArsC family
RK98_RS10420	COG3878	Protein conserved in bacteria
RK98_RS10430	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK98_RS10445	COG2011	ABC-type metal ion transport system permease component
RK98_RS10450	COG1464	Belongs to the NlpA lipoprotein family
RK98_RS10465	COG0396	ATPase activity
RK98_RS10470	COG0719	Fe-S assembly protein
RK98_RS10480	COG0822	iron-sulfur transferase activity
RK98_RS10610	COG1484	DNA-dependent DNA replication
RK98_RS10700	COG1783	phage Terminase large subunit
RK98_RS10830	COG1388	LysM domain
RK98_RS10830	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK98_RS10875	COG1253	flavin adenine dinucleotide binding
RK98_RS10890	COG1801	Protein of unknown function DUF72
RK98_RS10895	COG0730	response to heat
RK98_RS10910	COG4470	Protein conserved in bacteria
RK98_RS10930	COG2445	Protein of unknown function DUF86
RK98_RS10960	COG1696	Membrane protein involved in D-alanine export
RK98_RS10970	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RK98_RS10975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RK98_RS10980	COG4837	Protein of unknown function (DUF1462)
RK98_RS10985	COG1252	NADH dehydrogenase
RK98_RS10995	COG0316	Belongs to the HesB IscA family
RK98_RS11005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RK98_RS11010	COG2056	Na+-H+ antiporter family
RK98_RS11015	COG2050	protein possibly involved in aromatic compounds catabolism
RK98_RS11070	COG1098	S1 RNA binding domain
RK98_RS11075	COG1902	pentaerythritol trinitrate reductase activity
RK98_RS11090	COG0584	glycerophosphoryl diester phosphodiesterase
RK98_RS11110	COG0398	Pfam SNARE associated Golgi protein
RK98_RS11150	COG0561	phosphatase activity
RK98_RS11175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RK98_RS11190	COG1881	PFAM PEBP family protein
RK98_RS11220	COG0601	transmembrane transport
RK98_RS11225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK98_RS11230	COG0444	Belongs to the ABC transporter superfamily
RK98_RS11235	COG4608	Belongs to the ABC transporter superfamily
RK98_RS11240	COG4166	transmembrane transport
RK98_RS11245	COG0747	negative chemotaxis
RK98_RS11250	COG0444	Belongs to the ABC transporter superfamily
RK98_RS11255	COG4608	Belongs to the ABC transporter superfamily
RK98_RS11260	COG0601	transmembrane transport
RK98_RS11265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK98_RS11290	COG1164	Oligoendopeptidase f
RK98_RS11300	COG2346	COG2346, Truncated hemoglobins
RK98_RS11315	COG2357	RelA SpoT domain protein
RK98_RS11325	COG0564	pseudouridine synthase activity
RK98_RS11330	COG2239	Acts as a magnesium transporter
RK98_RS11335	COG0569	domain protein
RK98_RS11335	COG0475	glutathione-regulated potassium exporter activity
RK98_RS11345	COG0628	permease
RK98_RS11350	COG1115	amino acid carrier protein
RK98_RS11390	COG0861	Integral membrane protein TerC family
RK98_RS11400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK98_RS11405	COG0737	Belongs to the 5'-nucleotidase family
RK98_RS11420	COG4903	ComK protein
RK98_RS11435	COG4873	Protein conserved in bacteria
RK98_RS11490	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK98_RS11500	COG2314	TM2 domain
RK98_RS11505	COG0456	acetyltransferase
RK98_RS11510	COG1575	Belongs to the MenA family. Type 1 subfamily
RK98_RS11520	COG1169	isochorismate synthase
RK98_RS11530	COG2267	carboxylic ester hydrolase activity
RK98_RS11555	COG0436	Aminotransferase
RK98_RS11560	COG3594	Acyltransferase
RK98_RS11590	COG1316	TRANSCRIPTIONal
RK98_RS11635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RK98_RS11650	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RK98_RS11690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RK98_RS11695	COG4172	Belongs to the ABC transporter superfamily
RK98_RS11700	COG4721	ABC-type cobalt transport system, permease component
RK98_RS11725	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RK98_RS11745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RK98_RS11750	COG1271	oxidase subunit
RK98_RS11755	COG1294	oxidase, subunit
RK98_RS11760	COG0569	domain protein
RK98_RS11825	COG1176	ABC-type spermidine putrescine transport system, permease component I
RK98_RS11830	COG1177	transmembrane transport
RK98_RS11835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RK98_RS11860	COG0483	inositol monophosphate 1-phosphatase activity
RK98_RS11870	COG1217	gtp-binding protein TYPA
RK98_RS11880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RK98_RS11890	COG0772	Belongs to the SEDS family
RK98_RS11925	COG3679	Belongs to the UPF0342 family
RK98_RS11945	COG0742	ribosomal rna small subunit methyltransferase
RK98_RS12005	COG4509	Sortase family
RK98_RS12020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RK98_RS12065	COG1796	DNA polymerase
RK98_RS12065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RK98_RS12090	COG2009	succinate dehydrogenase
RK98_RS12095	COG1053	succinate dehydrogenase
RK98_RS12100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RK98_RS12230	COG1288	antiporter activity
RK98_RS12265	COG1011	Hydrolase
RK98_RS12290	COG4839	cell division protein FtsL
RK98_RS12295	COG0768	penicillin binding
RK98_RS12310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RK98_RS12315	COG0849	cell division
RK98_RS12330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RK98_RS12340	COG0762	integral membrane protein
RK98_RS12345	COG2302	S4 RNA-binding domain
RK98_RS12350	COG3599	regulation of cell shape
RK98_RS12360	COG2514	catechol 2,3-dioxygenase activity
RK98_RS12380	COG0564	pseudouridine synthase activity
RK98_RS12390	COG2233	PERMEase
RK98_RS12435	COG1293	RNA-binding protein homologous to eukaryotic snRNP
RK98_RS12450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RK98_RS12455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RK98_RS12465	COG2314	TM2 domain
RK98_RS12480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RK98_RS12480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RK98_RS12490	COG0631	protein serine/threonine phosphatase activity
RK98_RS12505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK98_RS12520	COG1302	Protein conserved in bacteria
RK98_RS12570	COG1196	nuclear chromosome segregation
RK98_RS12575	COG0552	protein localization to endoplasmic reticulum
RK98_RS12585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RK98_RS12640	COG2348	transferase activity, transferring amino-acyl groups
RK98_RS12645	COG0758	DNA mediated transformation
RK98_RS12745	COG0195	Participates in both transcription termination and antitermination
RK98_RS12750	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RK98_RS12775	COG0196	riboflavin kinase activity
RK98_RS12805	COG2188	Transcriptional regulator
RK98_RS12810	COG0612	Peptidase, M16
RK98_RS12815	COG0612	Peptidase, M16
RK98_RS12820	COG0300	oxidoreductase activity
RK98_RS12840	COG1058	Belongs to the CinA family
RK98_RS12840	COG1546	Belongs to the CinA family
RK98_RS12860	COG1692	metallophosphoesterase
RK98_RS12865	COG0674	pyruvate-flavodoxin oxidoreductase activity
RK98_RS12865	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RK98_RS12870	COG1013	pyruvate-flavodoxin oxidoreductase activity
RK98_RS12905	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RK98_RS12910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RK98_RS12935	COG1923	regulation of RNA biosynthetic process
RK98_RS12945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RK98_RS12950	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RK98_RS12955	COG0789	Transcriptional regulator
RK98_RS13055	COG2197	response regulator
RK98_RS13065	COG1525	nuclease
RK98_RS13080	COG0527	aspartate kinase activity
RK98_RS13085	COG0460	homoserine dehydrogenase
RK98_RS13090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RK98_RS13115	COG0833	amino acid
RK98_RS13145	COG2340	Cysteine-rich secretory protein family
RK98_RS13180	COG4846	Membrane protein involved in cytochrome C biogenesis
RK98_RS13200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK98_RS13215	COG0824	Thioesterase
RK98_RS13255	COG1115	amino acid carrier protein
RK98_RS13270	COG0628	permease
RK98_RS13295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RK98_RS13305	COG1363	Peptidase, m42
RK98_RS13310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK98_RS13315	COG0512	Glutamine amidotransferase of anthranilate synthase
RK98_RS13360	COG0561	phosphatase activity
RK98_RS13405	COG0704	Plays a role in the regulation of phosphate uptake
RK98_RS13415	COG0581	inorganic phosphate transmembrane transporter activity
RK98_RS13420	COG0573	inorganic phosphate transmembrane transporter activity
RK98_RS13440	COG0488	(ABC) transporter
RK98_RS13450	COG0527	aspartate kinase activity
RK98_RS13455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RK98_RS13530	COG4548	von Willebrand factor, type A
RK98_RS13535	COG0714	Associated with various cellular activities
RK98_RS13580	COG0671	phosphoesterase, PA-phosphatase related
RK98_RS13655	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RK98_RS13680	COG0531	amino acid
RK98_RS13695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK98_RS13700	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RK98_RS13715	COG0116	Belongs to the methyltransferase superfamily
RK98_RS13755	COG4499	WXG100 protein secretion system (Wss), protein YukC
RK98_RS13755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RK98_RS13765	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RK98_RS13770	COG3935	DnaD domain protein
RK98_RS13795	COG0438	transferase activity, transferring glycosyl groups
RK98_RS13800	COG1694	Mazg nucleotide pyrophosphohydrolase
RK98_RS13805	COG2738	Putative neutral zinc metallopeptidase
RK98_RS13810	COG4347	Protein of unknown function (DUF1405)
RK98_RS13850	COG0142	geranyltranstransferase activity
RK98_RS13915	COG0492	ferredoxin-NADP+ reductase activity
RK98_RS13930	COG0514	ATP-dependent DNA helicase (RecQ)
RK98_RS13940	COG1141	Ferredoxin
RK98_RS13985	COG0745	RESPONSE REGULATOR receiver
RK98_RS13990	COG1187	pseudouridine synthase activity
RK98_RS14015	COG0735	belongs to the Fur family
RK98_RS14020	COG0494	nUDIX hydrolase
RK98_RS14025	COG0667	Aldo Keto reductase
RK98_RS14035	COG4221	oxidoreductase activity
RK98_RS14050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RK98_RS14060	COG0366	Alpha amylase catalytic
RK98_RS14065	COG1609	Transcriptional regulator
RK98_RS14090	COG2195	Cleaves the N-terminal amino acid of tripeptides
RK98_RS14100	COG4129	membrane
RK98_RS14110	COG0508	dehydrogenase complex catalyzes the overall conversion of
RK98_RS14115	COG0022	dehydrogenase e1 component
RK98_RS14120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RK98_RS14125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK98_RS14130	COG0497	DNA recombination
RK98_RS14160	COG1302	Protein conserved in bacteria
RK98_RS14165	COG0439	Biotin carboxylase
RK98_RS14170	COG0511	ligase activity, forming carbon-carbon bonds
RK98_RS14180	COG0006	proline dipeptidase activity
RK98_RS14195	COG0095	Lipoate-protein ligase
RK98_RS14200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK98_RS14245	COG4537	Required for transformation and DNA binding
RK98_RS14250	COG1459	type II secretion system
RK98_RS14255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RK98_RS14260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK98_RS14265	COG0011	TIGRFAM Protein of
RK98_RS14270	COG1940	carbohydrate kinase activity
RK98_RS14275	COG4483	Protein conserved in bacteria
RK98_RS14285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RK98_RS14295	COG0768	penicillin binding
RK98_RS14310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK98_RS14315	COG1121	(ABC) transporter
RK98_RS14325	COG0513	Belongs to the DEAD box helicase family
RK98_RS14335	COG2384	SAM-dependent methyltransferase
RK98_RS14355	COG0517	IMP dehydrogenase activity
RK98_RS14375	COG0295	cytidine deaminase activity
RK98_RS14390	COG1702	phosphate starvation-inducible protein PhoH
RK98_RS14405	COG1030	water channel activity
RK98_RS14415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RK98_RS14420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RK98_RS14450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RK98_RS14465	COG1466	dna polymerase III delta subunit
RK98_RS14470	COG0658	competence protein
RK98_RS14470	COG2333	competence protein COMEC
RK98_RS14475	COG2131	deaminase
RK98_RS14480	COG2183	response to ionizing radiation
RK98_RS14485	COG2226	methyltransferase
RK98_RS14490	COG0799	negative regulation of ribosome biogenesis
RK98_RS14495	COG1713	HD superfamily hydrolase involved in NAD metabolism
RK98_RS14505	COG1534	Rna-binding protein
RK98_RS14515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RK98_RS14520	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RK98_RS14545	COG3177	Filamentation induced by cAMP protein fic
RK98_RS14550	COG1914	H( )-stimulated, divalent metal cation uptake system
RK98_RS14560	COG0439	Biotin carboxylase
RK98_RS14565	COG0511	ligase activity, forming carbon-carbon bonds
RK98_RS14570	COG1984	allophanate hydrolase subunit 2
RK98_RS14575	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RK98_RS14590	COG0826	peptidase U32
RK98_RS14595	COG0826	peptidase U32
RK98_RS14625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RK98_RS14650	COG1104	cysteine desulfurase activity
RK98_RS14655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK98_RS14665	COG3237	CsbD-like
RK98_RS14670	COG1959	2 iron, 2 sulfur cluster binding
RK98_RS14675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RK98_RS14680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RK98_RS14725	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RK98_RS14725	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RK98_RS14730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK98_RS14730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK98_RS14735	COG1862	Preprotein translocase
RK98_RS14775	COG2868	ribosomal protein
RK98_RS14820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RK98_RS14860	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RK98_RS14870	COG0285	dihydrofolate synthase activity
RK98_RS14880	COG2818	Glycosylase
RK98_RS14915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK98_RS14950	COG4112	unkown
RK98_RS14975	COG0833	amino acid
RK98_RS14990	COG1484	DNA-dependent DNA replication
RK98_RS15020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK98_RS15020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK98_RS15030	COG5002	protein histidine kinase activity
RK98_RS15035	COG0745	RESPONSE REGULATOR receiver
RK98_RS15050	COG0372	Belongs to the citrate synthase family
RK98_RS15055	COG1113	amino acid transport
RK98_RS15080	COG2314	TM2 domain