locus-tag	class	description
RK64_RS00025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RK64_RS00035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK64_RS00040	COG3527	Alpha-acetolactate decarboxylase
RK64_RS00055	COG0531	amino acid
RK64_RS00085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK64_RS00105	COG1012	belongs to the aldehyde dehydrogenase family
RK64_RS00115	COG1510	regulation of RNA biosynthetic process
RK64_RS00125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK64_RS00150	COG2851	Citrate transporter
RK64_RS00165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RK64_RS00175	COG0386	Belongs to the glutathione peroxidase family
RK64_RS00200	COG1136	(ABC) transporter
RK64_RS00205	COG2205	protein histidine kinase activity
RK64_RS00210	COG0745	RESPONSE REGULATOR receiver
RK64_RS00220	COG1785	Belongs to the alkaline phosphatase family
RK64_RS00230	COG1846	Transcriptional regulator
RK64_RS00275	COG1438	arginine binding
RK64_RS00295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK64_RS00295	COG3711	transcriptional antiterminator
RK64_RS00300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK64_RS00300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK64_RS00300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK64_RS00305	COG1482	cell wall glycoprotein biosynthetic process
RK64_RS00315	COG1705	Flagellar rod assembly protein muramidase FlgJ
RK64_RS00315	COG3942	CHAP domain
RK64_RS00320	COG1535	isochorismatase
RK64_RS00320	COG3433	isochorismatase activity
RK64_RS00335	COG0438	transferase activity, transferring glycosyl groups
RK64_RS00350	COG1073	alpha beta
RK64_RS00370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK64_RS00390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK64_RS00445	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RK64_RS00480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RK64_RS00565	COG0471	metal ion transport
RK64_RS00570	COG2962	Rard protein
RK64_RS00580	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RK64_RS00595	COG1136	(ABC) transporter
RK64_RS00600	COG0577	efflux transmembrane transporter activity
RK64_RS00630	COG1278	Cold shock
RK64_RS00650	COG1475	DNA binding
RK64_RS00690	COG2501	S4 domain
RK64_RS00705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RK64_RS00710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RK64_RS00740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RK64_RS00750	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RK64_RS00755	COG0359	binds to the 23S rRNA
RK64_RS00760	COG0305	Participates in initiation and elongation during chromosome replication
RK64_RS00795	COG4863	YycH protein
RK64_RS00805	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RK64_RS00810	COG0737	Belongs to the 5'-nucleotidase family
RK64_RS00845	COG0730	response to heat
RK64_RS00850	COG1937	Protein conserved in bacteria
RK64_RS00855	COG2210	Belongs to the sulfur carrier protein TusA family
RK64_RS00860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK64_RS00900	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK64_RS00915	COG0583	DNA-binding transcription factor activity
RK64_RS00935	COG0823	Involved in the tonB-independent uptake of proteins
RK64_RS00965	COG1473	amidohydrolase
RK64_RS00975	COG1283	sodium-dependent phosphate transmembrane transporter activity
RK64_RS00980	COG4716	Myosin-crossreactive antigen
RK64_RS00985	COG0697	spore germination
RK64_RS01000	COG1620	l-lactate permease
RK64_RS01005	COG1388	LysM domain
RK64_RS01020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK64_RS01025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK64_RS01030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK64_RS01040	COG2423	ornithine cyclodeaminase activity
RK64_RS01045	COG4264	IucA IucC family
RK64_RS01050	COG2814	Major facilitator Superfamily
RK64_RS01055	COG4264	IucA IucC family
RK64_RS01060	COG4264	IucA IucC family
RK64_RS01070	COG0019	diaminopimelate decarboxylase activity
RK64_RS01075	COG1475	DNA binding
RK64_RS01105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK64_RS01110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK64_RS01115	COG0438	transferase activity, transferring glycosyl groups
RK64_RS01150	COG0813	purine-nucleoside phosphorylase activity
RK64_RS01155	COG2814	Major facilitator Superfamily
RK64_RS01175	COG3639	organic phosphonate transmembrane transporter activity
RK64_RS01195	COG0737	Belongs to the 5'-nucleotidase family
RK64_RS01225	COG1454	alcohol dehydrogenase
RK64_RS01225	COG1012	belongs to the aldehyde dehydrogenase family
RK64_RS01250	COG1086	Polysaccharide biosynthesis protein
RK64_RS01260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK64_RS01290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK64_RS01300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RK64_RS01305	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK64_RS01315	COG2832	Protein of unknown function (DUF454)
RK64_RS01350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RK64_RS01355	COG1960	acyl-CoA dehydrogenase activity
RK64_RS01360	COG5609	conserved protein (DUF2294)
RK64_RS01410	COG1114	Component of the transport system for branched-chain amino acids
RK64_RS01415	COG1335	isochorismatase
RK64_RS01420	COG3961	Belongs to the TPP enzyme family
RK64_RS01450	COG1737	Transcriptional regulator
RK64_RS01485	COG0601	transmembrane transport
RK64_RS01490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK64_RS01500	COG0405	Gamma-glutamyltransferase
RK64_RS01520	COG3842	ATPase activity
RK64_RS01530	COG1175	transmembrane transport
RK64_RS01535	COG3833	ABC-type maltose transport systems, permease component
RK64_RS01540	COG0673	inositol 2-dehydrogenase activity
RK64_RS01545	COG0673	inositol 2-dehydrogenase activity
RK64_RS01555	COG1755	Isoprenylcysteine carboxyl methyltransferase
RK64_RS01615	COG0183	Belongs to the thiolase family
RK64_RS01625	COG1960	acyl-CoA dehydrogenase activity
RK64_RS01630	COG0318	PFAM AMP-dependent synthetase and ligase
RK64_RS01645	COG0747	negative chemotaxis
RK64_RS01650	COG3189	MarR family transcriptional regulator
RK64_RS01685	COG2190	(PTS) system
RK64_RS01685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK64_RS01685	COG1263	PTS System
RK64_RS01690	COG1957	nucleoside hydrolase
RK64_RS01710	COG3414	Phosphotransferase system galactitol-specific IIB component
RK64_RS01715	COG3775	system Galactitol-specific IIC component
RK64_RS01720	COG1063	alcohol dehydrogenase
RK64_RS01730	COG1063	alcohol dehydrogenase
RK64_RS01740	COG1063	alcohol dehydrogenase
RK64_RS01745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK64_RS01750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK64_RS01760	COG1063	alcohol dehydrogenase
RK64_RS01765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK64_RS01800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK64_RS01810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK64_RS01810	COG1263	PTS System
RK64_RS01810	COG2190	(PTS) system
RK64_RS01815	COG2723	6-phospho-beta-galactosidase activity
RK64_RS01825	COG2226	methyltransferase
RK64_RS01885	COG1131	(ABC) transporter
RK64_RS01915	COG3942	CHAP domain
RK64_RS01915	COG1388	LysM domain
RK64_RS02080	COG1114	Component of the transport system for branched-chain amino acids
RK64_RS02090	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
RK64_RS02100	COG0577	efflux transmembrane transporter activity
RK64_RS02130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK64_RS02135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RK64_RS02160	COG3314	Sporulation integral membrane protein YlbJ
RK64_RS02185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK64_RS02210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RK64_RS02215	COG3037	sugar-specific permease SgaT UlaA
RK64_RS02225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK64_RS02230	COG3711	transcriptional antiterminator
RK64_RS02255	COG2271	Major facilitator Superfamily
RK64_RS02260	COG0346	lactoylglutathione lyase activity
RK64_RS02265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK64_RS02270	COG0431	NADPH-dependent FMN reductase
RK64_RS02285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK64_RS02290	COG2822	iron ion transport
RK64_RS02300	COG0672	)-iron permease
RK64_RS02305	COG0805	protein transport
RK64_RS02310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RK64_RS02320	COG1476	TRANSCRIPTIONal
RK64_RS02330	COG1131	(ABC) transporter
RK64_RS02360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RK64_RS02360	COG0646	methionine synthase
RK64_RS02365	COG0626	cystathionine gamma-synthase activity
RK64_RS02370	COG0626	cystathionine gamma-synthase activity
RK64_RS02380	COG1475	DNA binding
RK64_RS02385	COG0668	transmembrane transport
RK64_RS02390	COG4481	Protein conserved in bacteria
RK64_RS02395	COG0012	GTP binding
RK64_RS02430	COG4974	Belongs to the 'phage' integrase family
RK64_RS02490	COG3634	alkyl hydroperoxide reductase activity
RK64_RS02505	COG1823	symporter activity
RK64_RS02540	COG2233	PERMEase
RK64_RS02580	COG3759	membrane
RK64_RS02710	COG0523	cobalamin synthesis protein
RK64_RS02735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RK64_RS02745	COG5609	conserved protein (DUF2294)
RK64_RS02760	COG1647	Serine aminopeptidase, S33
RK64_RS02770	COG0733	neurotransmitter:sodium symporter activity
RK64_RS02775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RK64_RS02780	COG0626	cystathionine gamma-synthase activity
RK64_RS02790	COG2011	ABC-type metal ion transport system permease component
RK64_RS02795	COG1464	Belongs to the NlpA lipoprotein family
RK64_RS02830	COG0583	DNA-binding transcription factor activity
RK64_RS02835	COG0067	glutamate synthase
RK64_RS02835	COG0070	glutamate synthase
RK64_RS02835	COG0069	glutamate synthase activity
RK64_RS02840	COG0493	'glutamate synthase
RK64_RS02850	COG1263	PTS System
RK64_RS02850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK64_RS02855	COG0366	Alpha amylase catalytic
RK64_RS02860	COG2188	Transcriptional regulator
RK64_RS02880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RK64_RS02920	COG1982	Orn Lys Arg decarboxylase major
RK64_RS02930	COG3870	Protein conserved in bacteria
RK64_RS02935	COG0470	DNA polymerase III
RK64_RS02940	COG1774	PSP1 C-terminal conserved region
RK64_RS02950	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RK64_RS02960	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RK64_RS02970	COG0084	hydrolase, TatD family'
RK64_RS02975	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK64_RS02985	COG4466	Protein conserved in bacteria
RK64_RS02995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RK64_RS03000	COG0251	oxidation-reduction process
RK64_RS03015	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RK64_RS03045	COG2244	polysaccharide biosynthetic process
RK64_RS03050	COG3956	TIGRFAM MazG family protein
RK64_RS03055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RK64_RS03065	COG1098	S1 RNA binding domain
RK64_RS03080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RK64_RS03105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RK64_RS03200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK64_RS03215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK64_RS03225	COG3880	PFAM UvrB UvrC protein
RK64_RS03240	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RK64_RS03245	COG4956	integral membrane protein (PIN domain superfamily)
RK64_RS03270	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RK64_RS03330	COG2813	Specifically methylates the guanine in position
RK64_RS03370	COG1473	amidohydrolase
RK64_RS03405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RK64_RS03410	COG1428	Deoxynucleoside kinase
RK64_RS03415	COG1428	Deoxynucleoside kinase
RK64_RS03425	COG0561	phosphatase activity
RK64_RS03445	COG4932	domain protein
RK64_RS03465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RK64_RS03480	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RK64_RS03580	COG0095	Lipoate-protein ligase
RK64_RS03585	COG0083	homoserine kinase activity
RK64_RS03605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK64_RS03695	COG0667	Aldo Keto reductase
RK64_RS03700	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK64_RS03710	COG1078	dGTPase activity
RK64_RS03750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK64_RS03755	COG4139	cobalamin transport
RK64_RS03805	COG4974	Belongs to the 'phage' integrase family
RK64_RS03850	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK64_RS03855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK64_RS03860	COG1121	(ABC) transporter
RK64_RS03865	COG1321	iron dependent repressor
RK64_RS03875	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RK64_RS03885	COG1682	transport, permease protein
RK64_RS03890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK64_RS03895	COG1216	Glycosyl transferase, family 2
RK64_RS03900	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RK64_RS03905	COG1686	Belongs to the peptidase S11 family
RK64_RS03910	COG1132	(ABC) transporter
RK64_RS03915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK64_RS03925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RK64_RS03930	COG1120	ATPase activity
RK64_RS03935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK64_RS03940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK64_RS03945	COG2376	Dihydroxyacetone kinase
RK64_RS03955	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RK64_RS03965	COG3949	Membrane
RK64_RS03990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK64_RS04005	COG1136	(ABC) transporter
RK64_RS04010	COG0577	efflux transmembrane transporter activity
RK64_RS04015	COG1392	Phosphate transport regulator
RK64_RS04020	COG0306	phosphate transporter
RK64_RS04025	COG3942	CHAP domain
RK64_RS04025	COG1388	LysM domain
RK64_RS04035	COG4977	sequence-specific DNA binding
RK64_RS04035	COG1917	Cupin 2, conserved barrel domain protein
RK64_RS04065	COG0583	DNA-binding transcription factor activity
RK64_RS04070	COG2814	Major facilitator Superfamily
RK64_RS04075	COG2839	Protein conserved in bacteria
RK64_RS04105	COG1611	Belongs to the LOG family
RK64_RS04125	COG4988	ABC transporter
RK64_RS04130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RK64_RS04140	COG0523	cobalamin synthesis protein
RK64_RS04145	COG4989	oxidoreductase activity
RK64_RS04155	COG0471	metal ion transport
RK64_RS04160	COG0415	Belongs to the DNA photolyase family
RK64_RS04190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RK64_RS04195	COG1349	DNA-binding transcription factor activity
RK64_RS04200	COG1105	Belongs to the carbohydrate kinase PfkB family
RK64_RS04205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK64_RS04205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK64_RS04205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK64_RS04210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RK64_RS04215	COG1253	flavin adenine dinucleotide binding
RK64_RS04220	COG0656	L-ascorbic acid biosynthetic process
RK64_RS04225	COG0463	Glycosyl transferase, family 2
RK64_RS04260	COG0720	synthase
RK64_RS04270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RK64_RS04270	COG0512	Glutamine amidotransferase of anthranilate synthase
RK64_RS04275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK64_RS04305	COG0488	(ABC) transporter
RK64_RS04310	COG0514	ATP-dependent DNA helicase (RecQ)
RK64_RS04315	COG0517	IMP dehydrogenase activity
RK64_RS04315	COG1125	glycine betaine transport
RK64_RS04320	COG1174	glycine betaine transport
RK64_RS04350	COG3104	oligopeptide transport
RK64_RS04380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK64_RS04385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK64_RS04400	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK64_RS04405	COG4605	iron ion homeostasis
RK64_RS04410	COG4604	ABC transporter, ATP-binding protein
RK64_RS04415	COG4607	ABC-type enterochelin transport system periplasmic component
RK64_RS04470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RK64_RS04475	COG1739	Uncharacterized protein family UPF0029
RK64_RS04485	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RK64_RS04490	COG1040	competence protein
RK64_RS04520	COG3942	CHAP domain
RK64_RS04520	COG1388	LysM domain
RK64_RS04580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RK64_RS04625	COG0149	triose-phosphate isomerase activity
RK64_RS04645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RK64_RS04650	COG1647	Serine aminopeptidase, S33
RK64_RS04655	COG0557	exoribonuclease II activity
RK64_RS04705	COG3266	domain, Protein
RK64_RS04705	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RK64_RS04730	COG1278	Cold shock
RK64_RS04770	COG0406	alpha-ribazole phosphatase activity
RK64_RS04775	COG1279	arginine transmembrane transporter activity
RK64_RS04800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK64_RS04805	COG1393	Belongs to the ArsC family
RK64_RS04820	COG3878	Protein conserved in bacteria
RK64_RS04830	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK64_RS04845	COG2011	ABC-type metal ion transport system permease component
RK64_RS04850	COG1464	Belongs to the NlpA lipoprotein family
RK64_RS04865	COG0396	ATPase activity
RK64_RS04870	COG0719	Fe-S assembly protein
RK64_RS04880	COG0822	iron-sulfur transferase activity
RK64_RS04905	COG1253	flavin adenine dinucleotide binding
RK64_RS04920	COG1801	Protein of unknown function DUF72
RK64_RS04925	COG0730	response to heat
RK64_RS04940	COG4470	Protein conserved in bacteria
RK64_RS04950	COG2445	Protein of unknown function DUF86
RK64_RS04980	COG1696	Membrane protein involved in D-alanine export
RK64_RS04990	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RK64_RS04995	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RK64_RS05000	COG4837	Protein of unknown function (DUF1462)
RK64_RS05005	COG1252	NADH dehydrogenase
RK64_RS05015	COG0316	Belongs to the HesB IscA family
RK64_RS05025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RK64_RS05030	COG2056	Na+-H+ antiporter family
RK64_RS05035	COG2050	protein possibly involved in aromatic compounds catabolism
RK64_RS05090	COG1098	S1 RNA binding domain
RK64_RS05095	COG1902	pentaerythritol trinitrate reductase activity
RK64_RS05115	COG0584	glycerophosphoryl diester phosphodiesterase
RK64_RS05130	COG0166	Belongs to the GPI family
RK64_RS05135	COG0398	Pfam SNARE associated Golgi protein
RK64_RS05175	COG0561	phosphatase activity
RK64_RS05200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RK64_RS05215	COG1881	PFAM PEBP family protein
RK64_RS05245	COG0601	transmembrane transport
RK64_RS05250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK64_RS05255	COG0444	Belongs to the ABC transporter superfamily
RK64_RS05260	COG4608	Belongs to the ABC transporter superfamily
RK64_RS05265	COG4166	transmembrane transport
RK64_RS05270	COG0747	negative chemotaxis
RK64_RS05275	COG0444	Belongs to the ABC transporter superfamily
RK64_RS05280	COG4608	Belongs to the ABC transporter superfamily
RK64_RS05285	COG0601	transmembrane transport
RK64_RS05290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK64_RS05315	COG1164	Oligoendopeptidase f
RK64_RS05325	COG2346	COG2346, Truncated hemoglobins
RK64_RS05340	COG2357	RelA SpoT domain protein
RK64_RS05350	COG0564	pseudouridine synthase activity
RK64_RS05355	COG2239	Acts as a magnesium transporter
RK64_RS05360	COG0475	glutathione-regulated potassium exporter activity
RK64_RS05360	COG0569	domain protein
RK64_RS05365	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RK64_RS05370	COG0628	permease
RK64_RS05375	COG1115	amino acid carrier protein
RK64_RS05415	COG0861	Integral membrane protein TerC family
RK64_RS05420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK64_RS05425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK64_RS05430	COG0737	Belongs to the 5'-nucleotidase family
RK64_RS05445	COG4903	ComK protein
RK64_RS05460	COG4873	Protein conserved in bacteria
RK64_RS05520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK64_RS05530	COG2314	TM2 domain
RK64_RS05535	COG0456	acetyltransferase
RK64_RS05540	COG1575	Belongs to the MenA family. Type 1 subfamily
RK64_RS05550	COG1169	isochorismate synthase
RK64_RS05560	COG2267	carboxylic ester hydrolase activity
RK64_RS05585	COG0436	Aminotransferase
RK64_RS05590	COG3594	Acyltransferase
RK64_RS05605	COG3266	domain, Protein
RK64_RS05605	COG4193	domain, Protein
RK64_RS05605	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK64_RS05620	COG1316	TRANSCRIPTIONal
RK64_RS05625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RK64_RS05665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RK64_RS05680	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RK64_RS05710	COG0138	bifunctional purine biosynthesis protein purh
RK64_RS05720	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RK64_RS05725	COG4172	Belongs to the ABC transporter superfamily
RK64_RS05730	COG4721	ABC-type cobalt transport system, permease component
RK64_RS05755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RK64_RS05780	COG1271	oxidase subunit
RK64_RS05785	COG1294	oxidase, subunit
RK64_RS05790	COG0569	domain protein
RK64_RS05855	COG1176	ABC-type spermidine putrescine transport system, permease component I
RK64_RS05860	COG1177	transmembrane transport
RK64_RS05865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RK64_RS05890	COG0483	inositol monophosphate 1-phosphatase activity
RK64_RS05900	COG1217	gtp-binding protein TYPA
RK64_RS05910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RK64_RS05920	COG0772	Belongs to the SEDS family
RK64_RS05955	COG3679	Belongs to the UPF0342 family
RK64_RS05975	COG0742	ribosomal rna small subunit methyltransferase
RK64_RS06030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK64_RS06040	COG4509	Sortase family
RK64_RS06055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RK64_RS06080	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
RK64_RS06090	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RK64_RS06090	COG1796	DNA polymerase
RK64_RS06115	COG2009	succinate dehydrogenase
RK64_RS06120	COG1053	succinate dehydrogenase
RK64_RS06125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RK64_RS06240	COG1288	antiporter activity
RK64_RS06275	COG1011	Hydrolase
RK64_RS06300	COG4839	cell division protein FtsL
RK64_RS06305	COG0768	penicillin binding
RK64_RS06320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RK64_RS06325	COG0849	cell division
RK64_RS06340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RK64_RS06350	COG0762	integral membrane protein
RK64_RS06355	COG2302	S4 RNA-binding domain
RK64_RS06360	COG3599	regulation of cell shape
RK64_RS06370	COG2514	catechol 2,3-dioxygenase activity
RK64_RS06390	COG0564	pseudouridine synthase activity
RK64_RS06400	COG2233	PERMEase
RK64_RS06445	COG1293	RNA-binding protein homologous to eukaryotic snRNP
RK64_RS06460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RK64_RS06465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RK64_RS06475	COG2314	TM2 domain
RK64_RS06490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RK64_RS06490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RK64_RS06500	COG0631	protein serine/threonine phosphatase activity
RK64_RS06515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK64_RS06530	COG1302	Protein conserved in bacteria
RK64_RS06540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RK64_RS06580	COG1196	nuclear chromosome segregation
RK64_RS06585	COG0552	protein localization to endoplasmic reticulum
RK64_RS06595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RK64_RS06655	COG0758	DNA mediated transformation
RK64_RS06755	COG0195	Participates in both transcription termination and antitermination
RK64_RS06760	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RK64_RS06785	COG0196	riboflavin kinase activity
RK64_RS06815	COG2188	Transcriptional regulator
RK64_RS06820	COG0612	Peptidase, M16
RK64_RS06825	COG0612	Peptidase, M16
RK64_RS06830	COG0300	oxidoreductase activity
RK64_RS06850	COG1058	Belongs to the CinA family
RK64_RS06850	COG1546	Belongs to the CinA family
RK64_RS06870	COG1692	metallophosphoesterase
RK64_RS06875	COG0674	pyruvate-flavodoxin oxidoreductase activity
RK64_RS06875	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RK64_RS06880	COG1013	pyruvate-flavodoxin oxidoreductase activity
RK64_RS06905	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK64_RS06915	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RK64_RS06920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RK64_RS06945	COG1923	regulation of RNA biosynthetic process
RK64_RS06955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RK64_RS06960	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RK64_RS06965	COG0789	Transcriptional regulator
RK64_RS07085	COG1131	(ABC) transporter
RK64_RS07100	COG2197	response regulator
RK64_RS07110	COG1525	nuclease
RK64_RS07125	COG0527	aspartate kinase activity
RK64_RS07130	COG0460	homoserine dehydrogenase
RK64_RS07135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RK64_RS07160	COG0833	amino acid
RK64_RS07190	COG2340	Cysteine-rich secretory protein family
RK64_RS07225	COG4846	Membrane protein involved in cytochrome C biogenesis
RK64_RS07245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK64_RS07260	COG0824	Thioesterase
RK64_RS07290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RK64_RS07300	COG1115	amino acid carrier protein
RK64_RS07315	COG0628	permease
RK64_RS07320	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RK64_RS07320	COG0392	lysyltransferase activity
RK64_RS07340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RK64_RS07345	COG0287	Prephenate dehydrogenase
RK64_RS07350	COG1363	Peptidase, m42
RK64_RS07355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK64_RS07360	COG0512	Glutamine amidotransferase of anthranilate synthase
RK64_RS07400	COG0561	phosphatase activity
RK64_RS07445	COG0704	Plays a role in the regulation of phosphate uptake
RK64_RS07455	COG0581	inorganic phosphate transmembrane transporter activity
RK64_RS07460	COG0573	inorganic phosphate transmembrane transporter activity
RK64_RS07480	COG0488	(ABC) transporter
RK64_RS07485	COG0527	aspartate kinase activity
RK64_RS07490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RK64_RS07570	COG4548	von Willebrand factor, type A
RK64_RS07575	COG0714	Associated with various cellular activities
RK64_RS07620	COG0671	phosphoesterase, PA-phosphatase related
RK64_RS07680	COG1413	lyase activity
RK64_RS07695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RK64_RS07720	COG0531	amino acid
RK64_RS07730	COG0686	Belongs to the AlaDH PNT family
RK64_RS07735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK64_RS07740	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RK64_RS07755	COG0116	Belongs to the methyltransferase superfamily
RK64_RS07795	COG4499	WXG100 protein secretion system (Wss), protein YukC
RK64_RS07795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RK64_RS07805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RK64_RS07810	COG3935	DnaD domain protein
RK64_RS07835	COG0438	transferase activity, transferring glycosyl groups
RK64_RS07840	COG1694	Mazg nucleotide pyrophosphohydrolase
RK64_RS07845	COG2738	Putative neutral zinc metallopeptidase
RK64_RS07850	COG4347	Protein of unknown function (DUF1405)
RK64_RS07855	COG5582	Belongs to the UPF0302 family
RK64_RS07870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RK64_RS07890	COG0142	geranyltranstransferase activity
RK64_RS07955	COG0492	ferredoxin-NADP+ reductase activity
RK64_RS07970	COG0514	ATP-dependent DNA helicase (RecQ)
RK64_RS07980	COG1141	Ferredoxin
RK64_RS08025	COG5002	protein histidine kinase activity
RK64_RS08030	COG0745	RESPONSE REGULATOR receiver
RK64_RS08035	COG1187	pseudouridine synthase activity
RK64_RS08060	COG0735	belongs to the Fur family
RK64_RS08065	COG0494	nUDIX hydrolase
RK64_RS08070	COG0667	Aldo Keto reductase
RK64_RS08080	COG4221	oxidoreductase activity
RK64_RS08095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RK64_RS08105	COG0366	Alpha amylase catalytic
RK64_RS08110	COG1609	Transcriptional regulator
RK64_RS08130	COG2195	Cleaves the N-terminal amino acid of tripeptides
RK64_RS08140	COG4129	membrane
RK64_RS08150	COG0508	dehydrogenase complex catalyzes the overall conversion of
RK64_RS08155	COG0022	dehydrogenase e1 component
RK64_RS08160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RK64_RS08165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK64_RS08170	COG0497	DNA recombination
RK64_RS08200	COG1302	Protein conserved in bacteria
RK64_RS08205	COG0439	Biotin carboxylase
RK64_RS08210	COG0511	ligase activity, forming carbon-carbon bonds
RK64_RS08220	COG0006	proline dipeptidase activity
RK64_RS08235	COG0095	Lipoate-protein ligase
RK64_RS08240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK64_RS08285	COG4537	Required for transformation and DNA binding
RK64_RS08290	COG1459	type II secretion system
RK64_RS08295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RK64_RS08300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK64_RS08305	COG0011	TIGRFAM Protein of
RK64_RS08310	COG1940	carbohydrate kinase activity
RK64_RS08315	COG4483	Protein conserved in bacteria
RK64_RS08325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RK64_RS08335	COG0768	penicillin binding
RK64_RS08350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK64_RS08355	COG1121	(ABC) transporter
RK64_RS08365	COG0513	Belongs to the DEAD box helicase family
RK64_RS08375	COG2384	SAM-dependent methyltransferase
RK64_RS08395	COG0517	IMP dehydrogenase activity
RK64_RS08410	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RK64_RS08415	COG0295	cytidine deaminase activity
RK64_RS08430	COG1702	phosphate starvation-inducible protein PhoH
RK64_RS08445	COG1030	water channel activity
RK64_RS08455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RK64_RS08460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RK64_RS08490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RK64_RS08510	COG1466	dna polymerase III delta subunit
RK64_RS08515	COG2333	competence protein COMEC
RK64_RS08515	COG0658	competence protein
RK64_RS08520	COG2131	deaminase
RK64_RS08530	COG2226	methyltransferase
RK64_RS08535	COG0799	negative regulation of ribosome biogenesis
RK64_RS08540	COG1713	HD superfamily hydrolase involved in NAD metabolism
RK64_RS08550	COG1534	Rna-binding protein
RK64_RS08560	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RK64_RS08565	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RK64_RS08585	COG3177	Filamentation induced by cAMP protein fic
RK64_RS08590	COG1914	H( )-stimulated, divalent metal cation uptake system
RK64_RS08600	COG0439	Biotin carboxylase
RK64_RS08605	COG0511	ligase activity, forming carbon-carbon bonds
RK64_RS08610	COG1984	allophanate hydrolase subunit 2
RK64_RS08615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RK64_RS08630	COG0826	peptidase U32
RK64_RS08635	COG0826	peptidase U32
RK64_RS08665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RK64_RS08680	COG1104	cysteine desulfurase activity
RK64_RS08685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK64_RS08695	COG3237	CsbD-like
RK64_RS08700	COG1959	2 iron, 2 sulfur cluster binding
RK64_RS08705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RK64_RS08710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RK64_RS08725	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RK64_RS08755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RK64_RS08755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RK64_RS08760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK64_RS08760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK64_RS08765	COG1862	Preprotein translocase
RK64_RS08805	COG2868	ribosomal protein
RK64_RS08850	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RK64_RS08860	COG0285	dihydrofolate synthase activity
RK64_RS08870	COG2818	Glycosylase
RK64_RS08905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK64_RS08910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RK64_RS08940	COG4112	unkown
RK64_RS08965	COG0833	amino acid
RK64_RS08970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RK64_RS08980	COG1484	DNA-dependent DNA replication
RK64_RS09010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK64_RS09010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK64_RS09020	COG5002	protein histidine kinase activity
RK64_RS09025	COG0745	RESPONSE REGULATOR receiver
RK64_RS09040	COG0372	Belongs to the citrate synthase family
RK64_RS09045	COG1113	amino acid transport
RK64_RS09075	COG0281	malic enzyme
RK64_RS09080	COG0587	DNA-directed DNA polymerase activity
RK64_RS09085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RK64_RS09095	COG4109	DRTGG domain
RK64_RS09135	COG0827	DNA restriction-modification system
RK64_RS09155	COG1104	cysteine desulfurase activity
RK64_RS09170	COG1956	GAF domain-containing protein
RK64_RS09190	COG0584	glycerophosphoryl diester phosphodiesterase
RK64_RS09195	COG1764	response to oxidative stress
RK64_RS09200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RK64_RS09205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK64_RS09220	COG1263	PTS System
RK64_RS09220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK64_RS09225	COG0204	Acyl-transferase
RK64_RS09230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK64_RS09250	COG5386	Cell surface protein
RK64_RS09260	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RK64_RS09265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK64_RS09270	COG0454	-acetyltransferase
RK64_RS09290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RK64_RS09290	COG1605	Chorismate mutase
RK64_RS09315	COG1674	ftsk spoiiie
RK64_RS09320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RK64_RS09330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK64_RS09335	COG1363	Peptidase, m42
RK64_RS09345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK64_RS09355	COG0510	thiamine kinase activity
RK64_RS09385	COG1187	pseudouridine synthase activity
RK64_RS09390	COG2244	polysaccharide biosynthetic process
RK64_RS09395	COG2081	HI0933 family
RK64_RS09415	COG2814	Major facilitator Superfamily
RK64_RS09420	COG1242	4 iron, 4 sulfur cluster binding
RK64_RS09425	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RK64_RS09440	COG2267	carboxylic ester hydrolase activity
RK64_RS09475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK64_RS09475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK64_RS09500	COG3266	domain, Protein
RK64_RS09500	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK64_RS09500	COG4193	domain, Protein
RK64_RS09510	COG1595	DNA-templated transcription, initiation
RK64_RS09530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RK64_RS09555	COG0656	L-ascorbic acid biosynthetic process
RK64_RS09580	COG1506	peptidase
RK64_RS09760	COG1131	(ABC) transporter
RK64_RS09880	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
RK64_RS09885	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RK64_RS09910	COG1131	(ABC) transporter
RK64_RS09915	COG0537	adenosine 5'-monophosphoramidase activity
RK64_RS09950	COG0420	3'-5' exonuclease activity
RK64_RS09980	COG2197	response regulator
RK64_RS09985	COG4585	Histidine kinase
RK64_RS09985	COG2203	Gaf domain
RK64_RS09990	COG0564	pseudouridine synthase activity
RK64_RS10030	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RK64_RS10035	COG1126	abc transporter atp-binding protein
RK64_RS10040	COG0765	amino acid transport
RK64_RS10215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK64_RS10220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RK64_RS10230	COG4129	membrane
RK64_RS10255	COG1988	membrane-bound metal-dependent
RK64_RS10270	COG1134	teichoic acid transport
RK64_RS10270	COG1388	LysM domain
RK64_RS10300	COG0535	radical SAM domain protein
RK64_RS10305	COG1607	acyl-coa hydrolase
RK64_RS10310	COG2309	aminopeptidase activity
RK64_RS10330	COG1295	ribonuclease BN
RK64_RS10335	COG2197	response regulator
RK64_RS10465	COG4851	CamS sex pheromone cAM373 precursor
RK64_RS10475	COG0210	DNA helicase
RK64_RS10485	COG4496	protein, YerC YecD
RK64_RS10525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RK64_RS10535	COG0077	Prephenate dehydratase
RK64_RS10545	COG0471	metal ion transport
RK64_RS10555	COG1335	isochorismatase
RK64_RS10570	COG1012	belongs to the aldehyde dehydrogenase family
RK64_RS10625	COG1131	(ABC) transporter
RK64_RS10640	COG1725	Transcriptional regulator
RK64_RS10690	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RK64_RS10695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK64_RS10700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK64_RS10720	COG5484	DNA packaging
RK64_RS10720	COG3728	DNA packaging
RK64_RS10795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK64_RS10800	COG1621	beta-fructofuranosidase activity
RK64_RS10805	COG1609	Transcriptional regulator
RK64_RS10810	COG0004	ammonium transporteR
RK64_RS10815	COG0425	Belongs to the sulfur carrier protein TusA family
RK64_RS10820	COG2391	methyltransferase activity
RK64_RS10830	COG0488	(ABC) transporter
RK64_RS10840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK64_RS10850	COG0456	acetyltransferase
RK64_RS10855	COG1214	PFAM Peptidase M22, glycoprotease
RK64_RS10860	COG0802	atpase or kinase
RK64_RS10875	COG0028	Belongs to the TPP enzyme family
RK64_RS10895	COG0473	3-isopropylmalate dehydrogenase activity
RK64_RS10950	COG2183	response to ionizing radiation
RK64_RS10955	COG1191	sigma factor activity
RK64_RS10965	COG1366	Belongs to the anti-sigma-factor antagonist family
RK64_RS11005	COG3428	Bacterial PH domain
RK64_RS11035	COG2205	protein histidine kinase activity
RK64_RS11040	COG0745	RESPONSE REGULATOR receiver
RK64_RS11050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RK64_RS11060	COG0772	Belongs to the SEDS family
RK64_RS11075	COG1937	Protein conserved in bacteria
RK64_RS11085	COG1418	mRNA catabolic process
RK64_RS11125	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RK64_RS11135	COG0629	single-stranded DNA binding
RK64_RS11210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK64_RS11235	COG0009	L-threonylcarbamoyladenylate synthase
RK64_RS11240	COG2890	protein-(glutamine-N5) methyltransferase activity
RK64_RS11265	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RK64_RS11295	COG0504	CTP synthase activity
RK64_RS11305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK64_RS11355	COG0813	purine-nucleoside phosphorylase activity
RK64_RS11360	COG0783	Belongs to the Dps family
RK64_RS11380	COG1482	cell wall glycoprotein biosynthetic process
RK64_RS11390	COG0702	epimerase
RK64_RS11395	COG0640	Transcriptional regulator
RK64_RS11430	COG0561	phosphatase activity
RK64_RS11435	COG1119	ATPase activity
RK64_RS11450	COG3711	transcriptional antiterminator
RK64_RS11460	COG0246	Mannitol dehydrogenase
RK64_RS11480	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RK64_RS11555	COG0489	protein tyrosine kinase activity
RK64_RS11560	COG2814	Major facilitator Superfamily
RK64_RS11575	COG1272	protein, Hemolysin III
RK64_RS11585	COG1988	membrane-bound metal-dependent
RK64_RS11595	COG3314	Sporulation integral membrane protein YlbJ
RK64_RS11600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK64_RS11605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK64_RS11610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK64_RS11620	COG3457	Alanine racemase
RK64_RS11625	COG4264	IucA IucC family
RK64_RS11630	COG2814	Major facilitator Superfamily
RK64_RS11660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK64_RS11670	COG2130	NADP-dependent
RK64_RS11715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RK64_RS11735	COG0656	L-ascorbic acid biosynthetic process
RK64_RS11740	COG0789	Transcriptional regulator
RK64_RS11750	COG5492	domain, Protein
RK64_RS11770	COG3527	Alpha-acetolactate decarboxylase
RK64_RS11775	COG0028	Belongs to the TPP enzyme family
RK64_RS11795	COG0542	response to heat
RK64_RS11880	COG0201	protein transport
RK64_RS11995	COG2252	PERMEase
RK64_RS12000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RK64_RS12000	COG0551	DNA topoisomerase type I activity
RK64_RS12040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK64_RS12115	COG1763	Mo-molybdopterin cofactor biosynthetic process
RK64_RS12135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RK64_RS12140	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RK64_RS12145	COG4149	molybdate abc transporter
RK64_RS12150	COG0725	ABC transporter, periplasmic molybdate-binding protein
RK64_RS12165	COG1268	BioY protein
RK64_RS12180	COG1960	acyl-CoA dehydrogenase activity
RK64_RS12185	COG4413	Urea transporter
RK64_RS12250	COG3942	CHAP domain
RK64_RS12260	COG1757	Na H antiporter
RK64_RS12275	COG3942	CHAP domain
RK64_RS12350	COG1113	amino acid transport
RK64_RS12370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK64_RS12375	COG0385	Bile acid
RK64_RS12385	COG1263	PTS System
RK64_RS12385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK64_RS12390	COG1737	Transcriptional regulator
RK64_RS12410	COG1028	Short-chain dehydrogenase reductase Sdr
RK64_RS12415	COG1473	amidohydrolase
RK64_RS12430	COG0583	DNA-binding transcription factor activity
RK64_RS12455	COG2258	MOSC domain
RK64_RS12475	COG1668	transmembrane transport
RK64_RS12480	COG4152	abc transporter atp-binding protein
RK64_RS12485	COG3152	Membrane
RK64_RS12500	COG0786	glutamate:sodium symporter activity
RK64_RS12510	COG0598	Magnesium transport protein CorA
RK64_RS12525	COG0657	acetylesterase activity
RK64_RS12535	COG2814	Major facilitator Superfamily
RK64_RS12540	COG1566	PFAM secretion protein HlyD family protein
RK64_RS12550	COG2814	Major facilitator Superfamily
RK64_RS12620	COG1620	l-lactate permease
RK64_RS12640	COG0604	alcohol dehydrogenase
RK64_RS12645	COG0456	acetyltransferase
RK64_RS12670	COG1511	domain protein
RK64_RS12685	COG1263	PTS System
RK64_RS12685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK64_RS12700	COG3871	stress protein (general stress protein 26)
RK64_RS12745	COG0789	Transcriptional regulator
RK64_RS12765	COG2181	nitrate reductase activity
RK64_RS12775	COG1140	nitrate reductase beta subunit
RK64_RS12780	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RK64_RS12790	COG2146	nitrite reductase [NAD(P)H] activity
RK64_RS12795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RK64_RS12805	COG0454	-acetyltransferase
RK64_RS12810	COG2116	formate transmembrane transporter activity
RK64_RS12825	COG3443	Belongs to the bacterial solute-binding protein 9 family
RK64_RS12825	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK64_RS12865	COG1126	abc transporter atp-binding protein
RK64_RS12870	COG0765	amino acid transport
RK64_RS12875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK64_RS12880	COG2814	Major facilitator Superfamily
RK64_RS12900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RK64_RS12950	COG0156	8-amino-7-oxononanoate synthase activity
RK64_RS12960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RK64_RS12965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RK64_RS12980	COG1132	(ABC) transporter
RK64_RS12985	COG1132	(ABC) transporter
RK64_RS12985	COG2375	cellular response to nickel ion
RK64_RS13005	COG1929	Belongs to the glycerate kinase type-1 family
RK64_RS13015	COG2814	Major facilitator Superfamily
RK64_RS13035	COG1113	amino acid transport
RK64_RS13050	COG0531	amino acid
RK64_RS13060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RK64_RS13075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK64_RS13085	COG1174	glycine betaine transport
RK64_RS13095	COG1174	glycine betaine transport
RK64_RS13115	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RK64_RS13125	COG0531	amino acid
RK64_RS13130	COG2272	Belongs to the type-B carboxylesterase lipase family
RK64_RS13135	COG2814	Major facilitator Superfamily
RK64_RS13140	COG0390	transport system, permease component
RK64_RS13145	COG4619	ABC transporter
RK64_RS13150	COG1363	Peptidase, m42
RK64_RS13170	COG4808	Protein conserved in bacteria
RK64_RS13175	COG0069	glutamate synthase activity
RK64_RS13190	COG1124	(ABC) transporter
RK64_RS13195	COG0444	Belongs to the ABC transporter superfamily
RK64_RS13200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK64_RS13205	COG0601	transmembrane transport
RK64_RS13210	COG0747	negative chemotaxis
RK64_RS13240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RK64_RS13245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK64_RS13335	COG0494	nUDIX hydrolase
RK64_RS13370	COG3583	domain protein
RK64_RS13375	COG1846	Transcriptional regulator
RK64_RS13380	COG1846	Transcriptional regulator
RK64_RS13395	COG4932	domain protein
RK64_RS13415	COG1070	Carbohydrate kinase
RK64_RS13420	COG1802	Transcriptional regulator
RK64_RS13425	COG0789	Transcriptional regulator
RK64_RS13430	COG2357	RelA SpoT domain protein
RK64_RS13435	COG4876	unkown
RK64_RS13445	COG2271	Major facilitator Superfamily
RK64_RS13450	COG0586	Pfam SNARE associated Golgi protein
RK64_RS13460	COG2814	Major facilitator Superfamily
RK64_RS13465	COG1846	Transcriptional regulator
RK64_RS13480	COG1131	(ABC) transporter
RK64_RS13500	COG0400	carboxylic ester hydrolase activity
RK64_RS13505	COG0346	lactoylglutathione lyase activity
RK64_RS13510	COG1846	Transcriptional regulator
RK64_RS13520	COG2514	catechol 2,3-dioxygenase activity
RK64_RS13535	COG0561	phosphatase activity
RK64_RS13540	COG1131	(ABC) transporter
RK64_RS13550	COG3764	Sortase (surface protein transpeptidase)
RK64_RS13570	COG1760	l-serine dehydratase
RK64_RS13575	COG1760	l-serine dehydratase
RK64_RS13590	COG0697	spore germination
RK64_RS13595	COG0657	acetylesterase activity
RK64_RS13615	COG0028	Belongs to the TPP enzyme family
RK64_RS13630	COG0583	DNA-binding transcription factor activity
RK64_RS13640	COG3942	CHAP domain
RK64_RS13665	COG3425	synthase
RK64_RS13670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RK64_RS13675	COG0542	response to heat
RK64_RS13695	COG2409	Drug exporters of the RND superfamily
RK64_RS13740	COG0436	Aminotransferase
RK64_RS13770	COG3942	CHAP domain
RK64_RS13775	COG2755	lipolytic protein G-D-S-L family
RK64_RS13775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RK64_RS13800	COG1309	transcriptional regulator
RK64_RS13845	COG0596	Alpha beta hydrolase
RK64_RS13885	COG3001	Fructosamine kinase
RK64_RS13890	COG0167	dihydroorotate dehydrogenase activity
RK64_RS14095	COG3942	CHAP domain
RK64_RS14095	COG1705	Flagellar rod assembly protein muramidase FlgJ
RK64_RS14105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RK64_RS14105	COG0551	DNA topoisomerase type I activity
RK64_RS14125	COG0629	single-stranded DNA binding
RK64_RS14165	COG0456	acetyltransferase