locus-tag	class	description
FD746_RS00015	COG2501	S4 domain
FD746_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FD746_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD746_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FD746_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
FD746_RS00110	COG4863	YycH protein
FD746_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FD746_RS00125	COG0737	Belongs to the 5'-nucleotidase family
FD746_RS00145	COG1388	LysM domain
FD746_RS00150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FD746_RS00155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FD746_RS00165	COG0446	pyridine nucleotide-disulphide oxidoreductase
FD746_RS00185	COG0640	Transcriptional regulator
FD746_RS00275	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FD746_RS00285	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FD746_RS00350	COG2814	Major facilitator Superfamily
FD746_RS00380	COG0456	acetyltransferase
FD746_RS00405	COG0655	NAD(P)H dehydrogenase (quinone) activity
FD746_RS00420	COG1073	alpha beta
FD746_RS00430	COG2226	methyltransferase
FD746_RS00440	COG0823	Involved in the tonB-independent uptake of proteins
FD746_RS00455	COG1473	amidohydrolase
FD746_RS00465	COG1283	sodium-dependent phosphate transmembrane transporter activity
FD746_RS00470	COG4716	Myosin-crossreactive antigen
FD746_RS00480	COG1620	l-lactate permease
FD746_RS00495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FD746_RS00500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FD746_RS00505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FD746_RS00515	COG2423	ornithine cyclodeaminase activity
FD746_RS00520	COG4264	IucA IucC family
FD746_RS00525	COG2814	Major facilitator Superfamily
FD746_RS00530	COG4264	IucA IucC family
FD746_RS00535	COG4264	IucA IucC family
FD746_RS00545	COG0019	diaminopimelate decarboxylase activity
FD746_RS00550	COG1475	DNA binding
FD746_RS00570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD746_RS00575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FD746_RS00580	COG0438	transferase activity, transferring glycosyl groups
FD746_RS00610	COG0813	purine-nucleoside phosphorylase activity
FD746_RS00615	COG2814	Major facilitator Superfamily
FD746_RS00635	COG3639	organic phosphonate transmembrane transporter activity
FD746_RS00655	COG0737	Belongs to the 5'-nucleotidase family
FD746_RS00670	COG1012	belongs to the aldehyde dehydrogenase family
FD746_RS00670	COG1454	alcohol dehydrogenase
FD746_RS00695	COG1086	Polysaccharide biosynthesis protein
FD746_RS00705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FD746_RS00735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FD746_RS00745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FD746_RS00750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FD746_RS00760	COG2832	Protein of unknown function (DUF454)
FD746_RS00795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FD746_RS00800	COG1960	acyl-CoA dehydrogenase activity
FD746_RS00805	COG5609	conserved protein (DUF2294)
FD746_RS00860	COG1309	transcriptional regulator
FD746_RS00865	COG1114	Component of the transport system for branched-chain amino acids
FD746_RS00870	COG1335	isochorismatase
FD746_RS00875	COG3961	Belongs to the TPP enzyme family
FD746_RS00905	COG1737	Transcriptional regulator
FD746_RS00930	COG0601	transmembrane transport
FD746_RS00935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FD746_RS00945	COG0405	Gamma-glutamyltransferase
FD746_RS00965	COG3842	ATPase activity
FD746_RS00975	COG1175	transmembrane transport
FD746_RS00980	COG3833	ABC-type maltose transport systems, permease component
FD746_RS00985	COG0673	inositol 2-dehydrogenase activity
FD746_RS00990	COG0673	inositol 2-dehydrogenase activity
FD746_RS01000	COG1755	Isoprenylcysteine carboxyl methyltransferase
FD746_RS01055	COG0183	Belongs to the thiolase family
FD746_RS01065	COG1960	acyl-CoA dehydrogenase activity
FD746_RS01070	COG0318	PFAM AMP-dependent synthetase and ligase
FD746_RS01090	COG0747	negative chemotaxis
FD746_RS01095	COG3189	MarR family transcriptional regulator
FD746_RS01120	COG1263	PTS System
FD746_RS01120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FD746_RS01120	COG2190	(PTS) system
FD746_RS01125	COG1957	nucleoside hydrolase
FD746_RS01145	COG3414	Phosphotransferase system galactitol-specific IIB component
FD746_RS01150	COG3775	system Galactitol-specific IIC component
FD746_RS01155	COG1063	alcohol dehydrogenase
FD746_RS01165	COG1063	alcohol dehydrogenase
FD746_RS01175	COG1063	alcohol dehydrogenase
FD746_RS01180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FD746_RS01190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FD746_RS01200	COG1063	alcohol dehydrogenase
FD746_RS01205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FD746_RS01245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FD746_RS01250	COG1263	PTS System
FD746_RS01250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FD746_RS01250	COG2190	(PTS) system
FD746_RS01255	COG2723	6-phospho-beta-galactosidase activity
FD746_RS01265	COG2226	methyltransferase
FD746_RS01355	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FD746_RS01440	COG0438	transferase activity, transferring glycosyl groups
FD746_RS01465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FD746_RS01470	COG2210	Belongs to the sulfur carrier protein TusA family
FD746_RS01475	COG1937	Protein conserved in bacteria
FD746_RS01480	COG0730	response to heat
FD746_RS01565	COG1131	(ABC) transporter
FD746_RS01585	COG3942	CHAP domain
FD746_RS01585	COG1388	LysM domain
FD746_RS01700	COG1114	Component of the transport system for branched-chain amino acids
FD746_RS01710	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FD746_RS01720	COG0577	efflux transmembrane transporter activity
FD746_RS01750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FD746_RS01755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FD746_RS01780	COG3314	Sporulation integral membrane protein YlbJ
FD746_RS01790	COG0582	viral genome integration into host DNA
FD746_RS02060	COG5280	Phage tail tape measure protein TP901
FD746_RS02060	COG3953	SLT domain
FD746_RS02100	COG2826	transposase and inactivated derivatives, IS30 family
FD746_RS02115	COG1388	LysM domain
FD746_RS02115	COG5632	N-Acetylmuramoyl-L-alanine amidase
FD746_RS02140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD746_RS02170	COG3037	sugar-specific permease SgaT UlaA
FD746_RS02180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD746_RS02185	COG3711	transcriptional antiterminator
FD746_RS02205	COG2271	Major facilitator Superfamily
FD746_RS02210	COG0346	lactoylglutathione lyase activity
FD746_RS02215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD746_RS02220	COG0431	NADPH-dependent FMN reductase
FD746_RS02235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FD746_RS02240	COG2822	iron ion transport
FD746_RS02250	COG0672	)-iron permease
FD746_RS02255	COG0805	protein transport
FD746_RS02260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FD746_RS02270	COG1476	TRANSCRIPTIONal
FD746_RS02280	COG1131	(ABC) transporter
FD746_RS02310	COG0646	methionine synthase
FD746_RS02310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FD746_RS02315	COG0626	cystathionine gamma-synthase activity
FD746_RS02320	COG0626	cystathionine gamma-synthase activity
FD746_RS02325	COG1475	DNA binding
FD746_RS02330	COG0668	transmembrane transport
FD746_RS02335	COG4481	Protein conserved in bacteria
FD746_RS02340	COG0012	GTP binding
FD746_RS02435	COG1823	symporter activity
FD746_RS02470	COG2233	PERMEase
FD746_RS02505	COG3759	membrane
FD746_RS02645	COG0523	cobalamin synthesis protein
FD746_RS02670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FD746_RS02680	COG5609	conserved protein (DUF2294)
FD746_RS02695	COG1647	Serine aminopeptidase, S33
FD746_RS02700	COG0733	neurotransmitter:sodium symporter activity
FD746_RS02705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FD746_RS02710	COG0626	cystathionine gamma-synthase activity
FD746_RS02720	COG2011	ABC-type metal ion transport system permease component
FD746_RS02725	COG1464	Belongs to the NlpA lipoprotein family
FD746_RS02735	COG2826	transposase and inactivated derivatives, IS30 family
FD746_RS02765	COG0583	DNA-binding transcription factor activity
FD746_RS02770	COG0067	glutamate synthase
FD746_RS02770	COG0069	glutamate synthase activity
FD746_RS02770	COG0070	glutamate synthase
FD746_RS02775	COG0493	'glutamate synthase
FD746_RS02785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FD746_RS02785	COG1263	PTS System
FD746_RS02790	COG0366	Alpha amylase catalytic
FD746_RS02795	COG2188	Transcriptional regulator
FD746_RS02815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FD746_RS02850	COG1982	Orn Lys Arg decarboxylase major
FD746_RS02860	COG3870	Protein conserved in bacteria
FD746_RS02865	COG0470	DNA polymerase III
FD746_RS02870	COG1774	PSP1 C-terminal conserved region
FD746_RS02880	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FD746_RS02890	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FD746_RS02900	COG0084	hydrolase, TatD family'
FD746_RS02905	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FD746_RS02915	COG4466	Protein conserved in bacteria
FD746_RS02925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FD746_RS02930	COG0251	oxidation-reduction process
FD746_RS02970	COG2244	polysaccharide biosynthetic process
FD746_RS02975	COG3956	TIGRFAM MazG family protein
FD746_RS02980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FD746_RS02990	COG1098	S1 RNA binding domain
FD746_RS03005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD746_RS03030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FD746_RS03125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FD746_RS03145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FD746_RS03155	COG3880	PFAM UvrB UvrC protein
FD746_RS03170	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FD746_RS03175	COG4956	integral membrane protein (PIN domain superfamily)
FD746_RS03195	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FD746_RS03255	COG2813	Specifically methylates the guanine in position
FD746_RS03295	COG1473	amidohydrolase
FD746_RS03325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FD746_RS03330	COG1428	Deoxynucleoside kinase
FD746_RS03335	COG1428	Deoxynucleoside kinase
FD746_RS03345	COG0561	phosphatase activity
FD746_RS03385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FD746_RS03500	COG0095	Lipoate-protein ligase
FD746_RS03505	COG0083	homoserine kinase activity
FD746_RS03525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD746_RS03560	COG0667	Aldo Keto reductase
FD746_RS03565	COG0655	NAD(P)H dehydrogenase (quinone) activity
FD746_RS03575	COG1078	dGTPase activity
FD746_RS03610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FD746_RS03615	COG4139	cobalamin transport
FD746_RS03710	COG0803	Belongs to the bacterial solute-binding protein 9 family
FD746_RS03715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FD746_RS03720	COG1121	(ABC) transporter
FD746_RS03725	COG1321	iron dependent repressor
FD746_RS03735	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FD746_RS03745	COG1682	transport, permease protein
FD746_RS03750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FD746_RS03760	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FD746_RS03765	COG1686	Belongs to the peptidase S11 family
FD746_RS03770	COG1132	(ABC) transporter
FD746_RS03775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FD746_RS03785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FD746_RS03790	COG1120	ATPase activity
FD746_RS03795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FD746_RS03800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FD746_RS03805	COG2376	Dihydroxyacetone kinase
FD746_RS03825	COG3949	Membrane
FD746_RS03845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD746_RS03860	COG1136	(ABC) transporter
FD746_RS03865	COG0577	efflux transmembrane transporter activity
FD746_RS03870	COG1392	Phosphate transport regulator
FD746_RS03875	COG0306	phosphate transporter
FD746_RS03880	COG3942	CHAP domain
FD746_RS03880	COG1388	LysM domain
FD746_RS03890	COG1917	Cupin 2, conserved barrel domain protein
FD746_RS03890	COG4977	sequence-specific DNA binding
FD746_RS03915	COG0583	DNA-binding transcription factor activity
FD746_RS03920	COG2814	Major facilitator Superfamily
FD746_RS03925	COG2839	Protein conserved in bacteria
FD746_RS03955	COG1611	Belongs to the LOG family
FD746_RS03975	COG4988	ABC transporter
FD746_RS03980	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FD746_RS03990	COG0523	cobalamin synthesis protein
FD746_RS03995	COG4989	oxidoreductase activity
FD746_RS04005	COG0471	metal ion transport
FD746_RS04010	COG0415	Belongs to the DNA photolyase family
FD746_RS04040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FD746_RS04045	COG1349	DNA-binding transcription factor activity
FD746_RS04050	COG1105	Belongs to the carbohydrate kinase PfkB family
FD746_RS04055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FD746_RS04055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD746_RS04055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FD746_RS04060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FD746_RS04065	COG1253	flavin adenine dinucleotide binding
FD746_RS04070	COG0656	L-ascorbic acid biosynthetic process
FD746_RS04110	COG0720	synthase
FD746_RS04120	COG0512	Glutamine amidotransferase of anthranilate synthase
FD746_RS04120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FD746_RS04125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FD746_RS04155	COG0488	(ABC) transporter
FD746_RS04160	COG0514	ATP-dependent DNA helicase (RecQ)
FD746_RS04165	COG1125	glycine betaine transport
FD746_RS04165	COG0517	IMP dehydrogenase activity
FD746_RS04170	COG1174	glycine betaine transport
FD746_RS04200	COG3104	oligopeptide transport
FD746_RS04230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FD746_RS04235	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FD746_RS04240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FD746_RS04245	COG4605	iron ion homeostasis
FD746_RS04250	COG4604	ABC transporter, ATP-binding protein
FD746_RS04255	COG4607	ABC-type enterochelin transport system periplasmic component
FD746_RS04310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FD746_RS04315	COG1739	Uncharacterized protein family UPF0029
FD746_RS04325	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FD746_RS04330	COG1040	competence protein
FD746_RS04355	COG3942	CHAP domain
FD746_RS04355	COG1388	LysM domain
FD746_RS04420	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FD746_RS04435	COG0281	malic enzyme
FD746_RS04485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FD746_RS04490	COG1647	Serine aminopeptidase, S33
FD746_RS04495	COG0557	exoribonuclease II activity
FD746_RS04510	COG0582	viral genome integration into host DNA
FD746_RS04590	COG0305	Participates in initiation and elongation during chromosome replication
FD746_RS04825	COG5632	N-Acetylmuramoyl-L-alanine amidase
FD746_RS04825	COG1388	LysM domain
FD746_RS04890	COG1278	Cold shock
FD746_RS04930	COG0406	alpha-ribazole phosphatase activity
FD746_RS04935	COG1279	arginine transmembrane transporter activity
FD746_RS04960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FD746_RS04965	COG1393	Belongs to the ArsC family
FD746_RS04980	COG3878	Protein conserved in bacteria
FD746_RS04985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FD746_RS05000	COG2011	ABC-type metal ion transport system permease component
FD746_RS05005	COG1464	Belongs to the NlpA lipoprotein family
FD746_RS05020	COG0396	ATPase activity
FD746_RS05025	COG0719	Fe-S assembly protein
FD746_RS05035	COG0822	iron-sulfur transferase activity
FD746_RS05055	COG1253	flavin adenine dinucleotide binding
FD746_RS05065	COG1801	Protein of unknown function DUF72
FD746_RS05070	COG0730	response to heat
FD746_RS05085	COG4470	Protein conserved in bacteria
FD746_RS05095	COG2445	Protein of unknown function DUF86
FD746_RS05125	COG1696	Membrane protein involved in D-alanine export
FD746_RS05135	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FD746_RS05140	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FD746_RS05145	COG4837	Protein of unknown function (DUF1462)
FD746_RS05150	COG1252	NADH dehydrogenase
FD746_RS05160	COG0316	Belongs to the HesB IscA family
FD746_RS05170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FD746_RS05175	COG2056	Na+-H+ antiporter family
FD746_RS05180	COG2050	protein possibly involved in aromatic compounds catabolism
FD746_RS05235	COG1098	S1 RNA binding domain
FD746_RS05240	COG1902	pentaerythritol trinitrate reductase activity
FD746_RS05255	COG0584	glycerophosphoryl diester phosphodiesterase
FD746_RS05275	COG0398	Pfam SNARE associated Golgi protein
FD746_RS05320	COG0561	phosphatase activity
FD746_RS05345	COG1881	PFAM PEBP family protein
FD746_RS05375	COG0601	transmembrane transport
FD746_RS05380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FD746_RS05385	COG0444	Belongs to the ABC transporter superfamily
FD746_RS05390	COG4608	Belongs to the ABC transporter superfamily
FD746_RS05395	COG4166	transmembrane transport
FD746_RS05400	COG0601	transmembrane transport
FD746_RS05405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FD746_RS05410	COG0444	Belongs to the ABC transporter superfamily
FD746_RS05415	COG4608	Belongs to the ABC transporter superfamily
FD746_RS05420	COG4166	transmembrane transport
FD746_RS05445	COG1164	Oligoendopeptidase f
FD746_RS05455	COG2346	COG2346, Truncated hemoglobins
FD746_RS05470	COG2357	RelA SpoT domain protein
FD746_RS05480	COG0564	pseudouridine synthase activity
FD746_RS05485	COG2239	Acts as a magnesium transporter
FD746_RS05490	COG0475	glutathione-regulated potassium exporter activity
FD746_RS05490	COG0569	domain protein
FD746_RS05500	COG0628	permease
FD746_RS05505	COG1115	amino acid carrier protein
FD746_RS05545	COG0861	Integral membrane protein TerC family
FD746_RS05555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FD746_RS05560	COG0737	Belongs to the 5'-nucleotidase family
FD746_RS05575	COG4903	ComK protein
FD746_RS05590	COG4873	Protein conserved in bacteria
FD746_RS05640	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FD746_RS05650	COG2314	TM2 domain
FD746_RS05655	COG0456	acetyltransferase
FD746_RS05660	COG1575	Belongs to the MenA family. Type 1 subfamily
FD746_RS05670	COG1169	isochorismate synthase
FD746_RS05710	COG0436	Aminotransferase
FD746_RS05715	COG3594	Acyltransferase
FD746_RS05745	COG1316	TRANSCRIPTIONal
FD746_RS05790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FD746_RS05805	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FD746_RS05850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FD746_RS05855	COG4172	Belongs to the ABC transporter superfamily
FD746_RS05860	COG4721	ABC-type cobalt transport system, permease component
FD746_RS05890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FD746_RS05915	COG1271	oxidase subunit
FD746_RS05955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FD746_RS06100	COG0740	serine-type endopeptidase activity
FD746_RS06195	COG1388	LysM domain
FD746_RS06195	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD746_RS06250	COG0569	domain protein
FD746_RS06315	COG1176	ABC-type spermidine putrescine transport system, permease component I
FD746_RS06320	COG1177	transmembrane transport
FD746_RS06325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FD746_RS06350	COG0483	inositol monophosphate 1-phosphatase activity
FD746_RS06360	COG1217	gtp-binding protein TYPA
FD746_RS06370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FD746_RS06380	COG0772	Belongs to the SEDS family
FD746_RS06410	COG3679	Belongs to the UPF0342 family
FD746_RS06415	COG0584	glycerophosphoryl diester phosphodiesterase
FD746_RS06430	COG0742	ribosomal rna small subunit methyltransferase
FD746_RS06490	COG4509	Sortase family
FD746_RS06505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FD746_RS06535	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FD746_RS06535	COG1796	DNA polymerase
FD746_RS06560	COG2009	succinate dehydrogenase
FD746_RS06565	COG1053	succinate dehydrogenase
FD746_RS06570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FD746_RS06685	COG1288	antiporter activity
FD746_RS06720	COG1011	Hydrolase
FD746_RS06745	COG4839	cell division protein FtsL
FD746_RS06750	COG0768	penicillin binding
FD746_RS06765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FD746_RS06770	COG0849	cell division
FD746_RS06785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FD746_RS06795	COG0762	integral membrane protein
FD746_RS06805	COG3599	regulation of cell shape
FD746_RS06815	COG2514	catechol 2,3-dioxygenase activity
FD746_RS06825	COG0564	pseudouridine synthase activity
FD746_RS06835	COG2233	PERMEase
FD746_RS06880	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FD746_RS06895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FD746_RS06900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FD746_RS06910	COG2314	TM2 domain
FD746_RS06925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FD746_RS06925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FD746_RS06935	COG0631	protein serine/threonine phosphatase activity
FD746_RS06950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FD746_RS06965	COG1302	Protein conserved in bacteria
FD746_RS07010	COG1196	nuclear chromosome segregation
FD746_RS07015	COG0552	protein localization to endoplasmic reticulum
FD746_RS07025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FD746_RS07090	COG0758	DNA mediated transformation
FD746_RS07185	COG0195	Participates in both transcription termination and antitermination
FD746_RS07190	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FD746_RS07215	COG0196	riboflavin kinase activity
FD746_RS07240	COG2188	Transcriptional regulator
FD746_RS07245	COG0612	Peptidase, M16
FD746_RS07250	COG0612	Peptidase, M16
FD746_RS07255	COG0300	oxidoreductase activity
FD746_RS07275	COG1058	Belongs to the CinA family
FD746_RS07275	COG1546	Belongs to the CinA family
FD746_RS07295	COG1692	metallophosphoesterase
FD746_RS07300	COG0674	pyruvate-flavodoxin oxidoreductase activity
FD746_RS07300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FD746_RS07305	COG1013	pyruvate-flavodoxin oxidoreductase activity
FD746_RS07310	COG2826	transposase and inactivated derivatives, IS30 family
FD746_RS07345	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FD746_RS07350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FD746_RS07375	COG1923	regulation of RNA biosynthetic process
FD746_RS07385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FD746_RS07390	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FD746_RS07395	COG0789	Transcriptional regulator
FD746_RS07475	COG1525	nuclease
FD746_RS07490	COG0527	aspartate kinase activity
FD746_RS07495	COG0460	homoserine dehydrogenase
FD746_RS07500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FD746_RS07525	COG0833	amino acid
FD746_RS07555	COG2340	Cysteine-rich secretory protein family
FD746_RS07590	COG4846	Membrane protein involved in cytochrome C biogenesis
FD746_RS07610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FD746_RS07625	COG0824	Thioesterase
FD746_RS07655	COG1115	amino acid carrier protein
FD746_RS07665	COG0628	permease
FD746_RS07690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FD746_RS07700	COG1363	Peptidase, m42
FD746_RS07705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FD746_RS07710	COG0512	Glutamine amidotransferase of anthranilate synthase
FD746_RS07750	COG0561	phosphatase activity
FD746_RS07800	COG0704	Plays a role in the regulation of phosphate uptake
FD746_RS07810	COG0581	inorganic phosphate transmembrane transporter activity
FD746_RS07815	COG0573	inorganic phosphate transmembrane transporter activity
FD746_RS07835	COG0488	(ABC) transporter
FD746_RS07840	COG0527	aspartate kinase activity
FD746_RS07845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FD746_RS07880	COG2808	Putative FMN-binding domain
FD746_RS07925	COG4548	von Willebrand factor, type A
FD746_RS07930	COG0714	Associated with various cellular activities
FD746_RS07975	COG0671	phosphoesterase, PA-phosphatase related
FD746_RS08050	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FD746_RS08070	COG0531	amino acid
FD746_RS08085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD746_RS08090	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FD746_RS08105	COG0116	Belongs to the methyltransferase superfamily
FD746_RS08140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FD746_RS08140	COG4499	WXG100 protein secretion system (Wss), protein YukC
FD746_RS08150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FD746_RS08155	COG3935	DnaD domain protein
FD746_RS08180	COG0438	transferase activity, transferring glycosyl groups
FD746_RS08185	COG1694	Mazg nucleotide pyrophosphohydrolase
FD746_RS08190	COG2738	Putative neutral zinc metallopeptidase
FD746_RS08195	COG4347	Protein of unknown function (DUF1405)
FD746_RS08235	COG0142	geranyltranstransferase activity
FD746_RS08290	COG0492	ferredoxin-NADP+ reductase activity
FD746_RS08305	COG0514	ATP-dependent DNA helicase (RecQ)
FD746_RS08315	COG1141	Ferredoxin
FD746_RS08350	COG5002	protein histidine kinase activity
FD746_RS08355	COG0745	RESPONSE REGULATOR receiver
FD746_RS08360	COG1187	pseudouridine synthase activity
FD746_RS08385	COG0735	belongs to the Fur family
FD746_RS08390	COG0494	nUDIX hydrolase
FD746_RS08395	COG0667	Aldo Keto reductase
FD746_RS08420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FD746_RS08430	COG0366	Alpha amylase catalytic
FD746_RS08435	COG1609	Transcriptional regulator
FD746_RS08455	COG2195	Cleaves the N-terminal amino acid of tripeptides
FD746_RS08465	COG4129	membrane
FD746_RS08475	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD746_RS08480	COG0022	dehydrogenase e1 component
FD746_RS08485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FD746_RS08490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD746_RS08495	COG0497	DNA recombination
FD746_RS08525	COG1302	Protein conserved in bacteria
FD746_RS08530	COG0439	Biotin carboxylase
FD746_RS08535	COG0511	ligase activity, forming carbon-carbon bonds
FD746_RS08545	COG0006	proline dipeptidase activity
FD746_RS08560	COG0095	Lipoate-protein ligase
FD746_RS08565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FD746_RS08610	COG4537	Required for transformation and DNA binding
FD746_RS08615	COG1459	type II secretion system
FD746_RS08620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FD746_RS08625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FD746_RS08630	COG0011	TIGRFAM Protein of
FD746_RS08635	COG1940	carbohydrate kinase activity
FD746_RS08640	COG4483	Protein conserved in bacteria
FD746_RS08650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FD746_RS08660	COG0768	penicillin binding
FD746_RS08675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FD746_RS08680	COG1121	(ABC) transporter
FD746_RS08690	COG0513	Belongs to the DEAD box helicase family
FD746_RS08700	COG2384	SAM-dependent methyltransferase
FD746_RS08720	COG0517	IMP dehydrogenase activity
FD746_RS08740	COG0295	cytidine deaminase activity
FD746_RS08755	COG1702	phosphate starvation-inducible protein PhoH
FD746_RS08770	COG1030	water channel activity
FD746_RS08780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FD746_RS08785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FD746_RS08815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FD746_RS08830	COG1466	dna polymerase III delta subunit
FD746_RS08835	COG2333	competence protein COMEC
FD746_RS08835	COG0658	competence protein
FD746_RS08840	COG2131	deaminase
FD746_RS08850	COG2226	methyltransferase
FD746_RS08855	COG0799	negative regulation of ribosome biogenesis
FD746_RS08860	COG1713	HD superfamily hydrolase involved in NAD metabolism
FD746_RS08870	COG1534	Rna-binding protein
FD746_RS08880	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FD746_RS08885	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FD746_RS08905	COG3177	Filamentation induced by cAMP protein fic
FD746_RS08910	COG1914	H( )-stimulated, divalent metal cation uptake system
FD746_RS08920	COG0439	Biotin carboxylase
FD746_RS08925	COG0511	ligase activity, forming carbon-carbon bonds
FD746_RS08930	COG1984	allophanate hydrolase subunit 2
FD746_RS08935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FD746_RS08950	COG0826	peptidase U32
FD746_RS08955	COG0826	peptidase U32
FD746_RS08985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD746_RS09000	COG1104	cysteine desulfurase activity
FD746_RS09005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD746_RS09015	COG3237	CsbD-like
FD746_RS09020	COG1959	2 iron, 2 sulfur cluster binding
FD746_RS09025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FD746_RS09030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FD746_RS09075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FD746_RS09075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FD746_RS09080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FD746_RS09080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FD746_RS09085	COG1862	Preprotein translocase
FD746_RS09125	COG2868	ribosomal protein
FD746_RS09170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FD746_RS09175	COG0285	dihydrofolate synthase activity
FD746_RS09185	COG2818	Glycosylase
FD746_RS09220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FD746_RS09255	COG4112	unkown
FD746_RS09275	COG0833	amino acid
FD746_RS09290	COG1484	DNA-dependent DNA replication
FD746_RS09320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD746_RS09320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD746_RS09330	COG5002	protein histidine kinase activity
FD746_RS09335	COG0745	RESPONSE REGULATOR receiver
FD746_RS09345	COG0372	Belongs to the citrate synthase family
FD746_RS09350	COG1113	amino acid transport
FD746_RS09375	COG0281	malic enzyme
FD746_RS09385	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FD746_RS09390	COG4109	DRTGG domain
FD746_RS09430	COG0827	DNA restriction-modification system
FD746_RS09440	COG0730	response to heat
FD746_RS09450	COG1104	cysteine desulfurase activity
FD746_RS09460	COG1956	GAF domain-containing protein
FD746_RS09475	COG0584	glycerophosphoryl diester phosphodiesterase
FD746_RS09480	COG1764	response to oxidative stress
FD746_RS09485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FD746_RS09490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FD746_RS09505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FD746_RS09505	COG1263	PTS System
FD746_RS09510	COG0204	Acyl-transferase
FD746_RS09515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD746_RS09550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FD746_RS09555	COG0454	-acetyltransferase
FD746_RS09575	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FD746_RS09575	COG1605	Chorismate mutase
FD746_RS09600	COG1674	ftsk spoiiie
FD746_RS09605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FD746_RS09615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FD746_RS09620	COG1363	Peptidase, m42
FD746_RS09630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FD746_RS09640	COG0510	thiamine kinase activity
FD746_RS09660	COG1187	pseudouridine synthase activity
FD746_RS09665	COG2244	polysaccharide biosynthetic process
FD746_RS09670	COG2081	HI0933 family
FD746_RS09690	COG2814	Major facilitator Superfamily
FD746_RS09695	COG1242	4 iron, 4 sulfur cluster binding
FD746_RS09700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FD746_RS09710	COG2267	carboxylic ester hydrolase activity
FD746_RS09745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD746_RS09745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD746_RS09765	COG5632	N-Acetylmuramoyl-L-alanine amidase
FD746_RS09765	COG4193	domain, Protein
FD746_RS09765	COG3266	domain, Protein
FD746_RS09800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FD746_RS09820	COG0656	L-ascorbic acid biosynthetic process
FD746_RS09840	COG1506	peptidase
FD746_RS09845	COG2816	NAD+ diphosphatase activity
FD746_RS10035	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FD746_RS10065	COG1131	(ABC) transporter
FD746_RS10070	COG0537	adenosine 5'-monophosphoramidase activity
FD746_RS10105	COG0420	3'-5' exonuclease activity
FD746_RS10135	COG2197	response regulator
FD746_RS10140	COG4585	Histidine kinase
FD746_RS10140	COG2203	Gaf domain
FD746_RS10145	COG0564	pseudouridine synthase activity
FD746_RS10180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FD746_RS10185	COG1126	abc transporter atp-binding protein
FD746_RS10190	COG0765	amino acid transport
FD746_RS10360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FD746_RS10365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FD746_RS10375	COG4129	membrane
FD746_RS10395	COG1194	a g-specific adenine glycosylase
FD746_RS10400	COG1988	membrane-bound metal-dependent
FD746_RS10415	COG1134	teichoic acid transport
FD746_RS10415	COG1388	LysM domain
FD746_RS10445	COG0535	radical SAM domain protein
FD746_RS10450	COG1607	acyl-coa hydrolase
FD746_RS10455	COG2309	aminopeptidase activity
FD746_RS10475	COG1295	ribonuclease BN
FD746_RS10590	COG4851	CamS sex pheromone cAM373 precursor
FD746_RS10610	COG4496	protein, YerC YecD
FD746_RS10645	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FD746_RS10655	COG0077	Prephenate dehydratase
FD746_RS10675	COG1335	isochorismatase
FD746_RS10690	COG1012	belongs to the aldehyde dehydrogenase family
FD746_RS10700	COG3682	Transcriptional regulator
FD746_RS10730	COG4974	Belongs to the 'phage' integrase family
FD746_RS10780	COG1131	(ABC) transporter
FD746_RS10795	COG1725	Transcriptional regulator
FD746_RS10840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FD746_RS10920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FD746_RS10925	COG1621	beta-fructofuranosidase activity
FD746_RS10930	COG1609	Transcriptional regulator
FD746_RS10935	COG0004	ammonium transporteR
FD746_RS10940	COG0425	Belongs to the sulfur carrier protein TusA family
FD746_RS10945	COG2391	methyltransferase activity
FD746_RS10955	COG0488	(ABC) transporter
FD746_RS10965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FD746_RS10975	COG0456	acetyltransferase
FD746_RS10980	COG1214	PFAM Peptidase M22, glycoprotease
FD746_RS10985	COG0802	atpase or kinase
FD746_RS11000	COG0028	Belongs to the TPP enzyme family
FD746_RS11070	COG2183	response to ionizing radiation
FD746_RS11075	COG1191	sigma factor activity
FD746_RS11085	COG1366	Belongs to the anti-sigma-factor antagonist family
FD746_RS11090	COG2208	phosphoserine phosphatase activity
FD746_RS11120	COG3428	Bacterial PH domain
FD746_RS11150	COG2205	protein histidine kinase activity
FD746_RS11155	COG0745	RESPONSE REGULATOR receiver
FD746_RS11165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FD746_RS11175	COG0772	Belongs to the SEDS family
FD746_RS11190	COG1937	Protein conserved in bacteria
FD746_RS11200	COG1418	mRNA catabolic process
FD746_RS11245	COG0629	single-stranded DNA binding
FD746_RS11320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FD746_RS11345	COG0009	L-threonylcarbamoyladenylate synthase
FD746_RS11350	COG2890	protein-(glutamine-N5) methyltransferase activity
FD746_RS11375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FD746_RS11415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FD746_RS11460	COG0813	purine-nucleoside phosphorylase activity
FD746_RS11465	COG0783	Belongs to the Dps family
FD746_RS11485	COG1482	cell wall glycoprotein biosynthetic process
FD746_RS11490	COG0702	epimerase
FD746_RS11495	COG0640	Transcriptional regulator
FD746_RS11535	COG0561	phosphatase activity
FD746_RS11540	COG1119	ATPase activity
FD746_RS11560	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FD746_RS11625	COG3711	transcriptional antiterminator
FD746_RS11655	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FD746_RS11715	COG0489	protein tyrosine kinase activity
FD746_RS11720	COG2814	Major facilitator Superfamily
FD746_RS11735	COG1272	protein, Hemolysin III
FD746_RS11745	COG1988	membrane-bound metal-dependent
FD746_RS11755	COG3314	Sporulation integral membrane protein YlbJ
FD746_RS11760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FD746_RS11765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FD746_RS11770	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FD746_RS11780	COG3457	Alanine racemase
FD746_RS11785	COG4264	IucA IucC family
FD746_RS11790	COG2814	Major facilitator Superfamily
FD746_RS11815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FD746_RS11825	COG2130	NADP-dependent
FD746_RS11890	COG0656	L-ascorbic acid biosynthetic process
FD746_RS11895	COG0789	Transcriptional regulator
FD746_RS11905	COG5492	domain, Protein
FD746_RS11920	COG0438	transferase activity, transferring glycosyl groups
FD746_RS11935	COG3527	Alpha-acetolactate decarboxylase
FD746_RS11940	COG0028	Belongs to the TPP enzyme family
FD746_RS11950	COG2826	transposase and inactivated derivatives, IS30 family
FD746_RS12025	COG0201	protein transport
FD746_RS12140	COG2252	PERMEase
FD746_RS12185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD746_RS12245	COG1763	Mo-molybdopterin cofactor biosynthetic process
FD746_RS12265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FD746_RS12270	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FD746_RS12275	COG4149	molybdate abc transporter
FD746_RS12280	COG0725	ABC transporter, periplasmic molybdate-binding protein
FD746_RS12295	COG1268	BioY protein
FD746_RS12310	COG1960	acyl-CoA dehydrogenase activity
FD746_RS12315	COG4413	Urea transporter
FD746_RS12385	COG1757	Na H antiporter
FD746_RS12400	COG3942	CHAP domain
FD746_RS12455	COG1266	CAAX protease self-immunity
FD746_RS12470	COG1113	amino acid transport
FD746_RS12490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FD746_RS12495	COG0385	Bile acid
FD746_RS12505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FD746_RS12505	COG1263	PTS System
FD746_RS12510	COG1737	Transcriptional regulator
FD746_RS12530	COG1028	Short-chain dehydrogenase reductase Sdr
FD746_RS12535	COG1473	amidohydrolase
FD746_RS12550	COG0583	DNA-binding transcription factor activity
FD746_RS12570	COG2258	MOSC domain
FD746_RS12590	COG1668	transmembrane transport
FD746_RS12595	COG4152	abc transporter atp-binding protein
FD746_RS12600	COG3152	Membrane
FD746_RS12615	COG0786	glutamate:sodium symporter activity
FD746_RS12625	COG0598	Magnesium transport protein CorA
FD746_RS12640	COG0657	acetylesterase activity
FD746_RS12650	COG2814	Major facilitator Superfamily
FD746_RS12655	COG1566	PFAM secretion protein HlyD family protein
FD746_RS12670	COG2814	Major facilitator Superfamily
FD746_RS12730	COG1620	l-lactate permease
FD746_RS12740	COG2826	transposase and inactivated derivatives, IS30 family
FD746_RS12755	COG0604	alcohol dehydrogenase
FD746_RS12780	COG1511	domain protein
FD746_RS12795	COG1263	PTS System
FD746_RS12795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FD746_RS12810	COG3871	stress protein (general stress protein 26)
FD746_RS12855	COG0789	Transcriptional regulator
FD746_RS12875	COG2181	nitrate reductase activity
FD746_RS12885	COG1140	nitrate reductase beta subunit
FD746_RS12890	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FD746_RS12900	COG2146	nitrite reductase [NAD(P)H] activity
FD746_RS12905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FD746_RS12915	COG0454	-acetyltransferase
FD746_RS12920	COG2116	formate transmembrane transporter activity
FD746_RS12935	COG3443	Belongs to the bacterial solute-binding protein 9 family
FD746_RS12935	COG0803	Belongs to the bacterial solute-binding protein 9 family
FD746_RS12960	COG1126	abc transporter atp-binding protein
FD746_RS12965	COG0765	amino acid transport
FD746_RS12970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD746_RS12975	COG2814	Major facilitator Superfamily
FD746_RS12990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FD746_RS13035	COG0156	8-amino-7-oxononanoate synthase activity
FD746_RS13045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FD746_RS13050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FD746_RS13060	COG1132	(ABC) transporter
FD746_RS13065	COG1132	(ABC) transporter
FD746_RS13065	COG2375	cellular response to nickel ion
FD746_RS13080	COG1929	Belongs to the glycerate kinase type-1 family
FD746_RS13090	COG2814	Major facilitator Superfamily
FD746_RS13110	COG1113	amino acid transport
FD746_RS13120	COG0531	amino acid
FD746_RS13135	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FD746_RS13145	COG1174	glycine betaine transport
FD746_RS13155	COG1174	glycine betaine transport
FD746_RS13175	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FD746_RS13180	COG0531	amino acid
FD746_RS13185	COG2272	Belongs to the type-B carboxylesterase lipase family
FD746_RS13190	COG2814	Major facilitator Superfamily
FD746_RS13195	COG0390	transport system, permease component
FD746_RS13200	COG4619	ABC transporter
FD746_RS13205	COG1363	Peptidase, m42
FD746_RS13210	COG4808	Protein conserved in bacteria
FD746_RS13215	COG0069	glutamate synthase activity
FD746_RS13230	COG1124	(ABC) transporter
FD746_RS13240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FD746_RS13245	COG0601	transmembrane transport
FD746_RS13250	COG0747	negative chemotaxis
FD746_RS13275	COG1028	Short-chain dehydrogenase reductase Sdr
FD746_RS13280	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FD746_RS13285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FD746_RS13435	COG1070	Carbohydrate kinase
FD746_RS13440	COG1802	Transcriptional regulator
FD746_RS13445	COG0789	Transcriptional regulator
FD746_RS13450	COG2357	RelA SpoT domain protein
FD746_RS13455	COG4876	unkown
FD746_RS13470	COG2271	Major facilitator Superfamily
FD746_RS13475	COG0586	Pfam SNARE associated Golgi protein
FD746_RS13485	COG2814	Major facilitator Superfamily
FD746_RS13490	COG1846	Transcriptional regulator
FD746_RS13505	COG1131	(ABC) transporter
FD746_RS13530	COG0400	carboxylic ester hydrolase activity
FD746_RS13535	COG0346	lactoylglutathione lyase activity
FD746_RS13540	COG1846	Transcriptional regulator
FD746_RS13550	COG2514	catechol 2,3-dioxygenase activity
FD746_RS13565	COG0561	phosphatase activity
FD746_RS13570	COG3764	Sortase (surface protein transpeptidase)
FD746_RS13590	COG1760	l-serine dehydratase
FD746_RS13595	COG1760	l-serine dehydratase
FD746_RS13610	COG0697	spore germination
FD746_RS13615	COG0657	acetylesterase activity
FD746_RS13635	COG0028	Belongs to the TPP enzyme family
FD746_RS13650	COG0583	DNA-binding transcription factor activity
FD746_RS13660	COG3942	CHAP domain
FD746_RS13670	COG3425	synthase
FD746_RS13675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FD746_RS13745	COG0436	Aminotransferase
FD746_RS13850	COG0596	Alpha beta hydrolase
FD746_RS13885	COG3001	Fructosamine kinase
FD746_RS13890	COG0167	dihydroorotate dehydrogenase activity
FD746_RS13935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FD746_RS13940	COG3527	Alpha-acetolactate decarboxylase
FD746_RS13950	COG0531	amino acid
FD746_RS13980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FD746_RS14000	COG1012	belongs to the aldehyde dehydrogenase family
FD746_RS14010	COG1510	regulation of RNA biosynthetic process
FD746_RS14015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FD746_RS14040	COG2851	Citrate transporter
FD746_RS14055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FD746_RS14065	COG0386	Belongs to the glutathione peroxidase family
FD746_RS14090	COG1136	(ABC) transporter
FD746_RS14095	COG2205	protein histidine kinase activity
FD746_RS14100	COG0745	RESPONSE REGULATOR receiver
FD746_RS14110	COG1785	Belongs to the alkaline phosphatase family
FD746_RS14120	COG1846	Transcriptional regulator
FD746_RS14160	COG1438	arginine binding
FD746_RS14180	COG3711	transcriptional antiterminator
FD746_RS14180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD746_RS14185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FD746_RS14185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD746_RS14185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FD746_RS14190	COG1482	cell wall glycoprotein biosynthetic process
FD746_RS14200	COG3942	CHAP domain
FD746_RS14200	COG1705	Flagellar rod assembly protein muramidase FlgJ
FD746_RS14205	COG1535	isochorismatase
FD746_RS14205	COG3433	isochorismatase activity
FD746_RS14220	COG0438	transferase activity, transferring glycosyl groups
FD746_RS14235	COG1073	alpha beta
FD746_RS14255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FD746_RS14285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FD746_RS14380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FD746_RS14450	COG0471	metal ion transport
FD746_RS14455	COG2962	Rard protein
FD746_RS14465	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FD746_RS14480	COG1136	(ABC) transporter
FD746_RS14485	COG0577	efflux transmembrane transporter activity
FD746_RS14495	COG1278	Cold shock
FD746_RS14515	COG1475	DNA binding