locus-tag	class	description
CTB89_RS00015	COG2501	S4 domain
CTB89_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTB89_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTB89_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CTB89_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
CTB89_RS00120	COG4863	YycH protein
CTB89_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CTB89_RS00135	COG0737	Belongs to the 5'-nucleotidase family
CTB89_RS00185	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTB89_RS00200	COG1073	alpha beta
CTB89_RS00225	COG2226	methyltransferase
CTB89_RS00235	COG0823	Involved in the tonB-independent uptake of proteins
CTB89_RS00280	COG1473	amidohydrolase
CTB89_RS00290	COG1283	sodium-dependent phosphate transmembrane transporter activity
CTB89_RS00295	COG4716	Myosin-crossreactive antigen
CTB89_RS00305	COG1620	l-lactate permease
CTB89_RS00325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTB89_RS00330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTB89_RS00335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTB89_RS00345	COG2423	ornithine cyclodeaminase activity
CTB89_RS00350	COG4264	IucA IucC family
CTB89_RS00355	COG2814	Major facilitator Superfamily
CTB89_RS00360	COG4264	IucA IucC family
CTB89_RS00365	COG4264	IucA IucC family
CTB89_RS00375	COG0019	diaminopimelate decarboxylase activity
CTB89_RS00380	COG1475	DNA binding
CTB89_RS00410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTB89_RS00415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTB89_RS00420	COG0438	transferase activity, transferring glycosyl groups
CTB89_RS00455	COG0813	purine-nucleoside phosphorylase activity
CTB89_RS00460	COG2814	Major facilitator Superfamily
CTB89_RS00480	COG3639	organic phosphonate transmembrane transporter activity
CTB89_RS00500	COG0737	Belongs to the 5'-nucleotidase family
CTB89_RS00515	COG1454	alcohol dehydrogenase
CTB89_RS00515	COG1012	belongs to the aldehyde dehydrogenase family
CTB89_RS00540	COG1086	Polysaccharide biosynthesis protein
CTB89_RS00550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTB89_RS00580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTB89_RS00590	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTB89_RS00595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTB89_RS00605	COG2832	Protein of unknown function (DUF454)
CTB89_RS00640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTB89_RS00645	COG1960	acyl-CoA dehydrogenase activity
CTB89_RS00665	COG3477	response to acidic pH
CTB89_RS00690	COG1114	Component of the transport system for branched-chain amino acids
CTB89_RS00695	COG1335	isochorismatase
CTB89_RS00700	COG3961	Belongs to the TPP enzyme family
CTB89_RS00730	COG1737	Transcriptional regulator
CTB89_RS00755	COG0601	transmembrane transport
CTB89_RS00760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTB89_RS00770	COG0405	Gamma-glutamyltransferase
CTB89_RS00790	COG3842	ATPase activity
CTB89_RS00800	COG1175	transmembrane transport
CTB89_RS00805	COG3833	ABC-type maltose transport systems, permease component
CTB89_RS00810	COG0673	inositol 2-dehydrogenase activity
CTB89_RS00815	COG0673	inositol 2-dehydrogenase activity
CTB89_RS00825	COG1755	Isoprenylcysteine carboxyl methyltransferase
CTB89_RS00885	COG0183	Belongs to the thiolase family
CTB89_RS00895	COG1960	acyl-CoA dehydrogenase activity
CTB89_RS00900	COG0318	PFAM AMP-dependent synthetase and ligase
CTB89_RS00915	COG0747	negative chemotaxis
CTB89_RS00920	COG3189	MarR family transcriptional regulator
CTB89_RS00955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTB89_RS00955	COG1263	PTS System
CTB89_RS00955	COG2190	(PTS) system
CTB89_RS00960	COG1957	nucleoside hydrolase
CTB89_RS00980	COG3414	Phosphotransferase system galactitol-specific IIB component
CTB89_RS00985	COG3775	system Galactitol-specific IIC component
CTB89_RS00990	COG1063	alcohol dehydrogenase
CTB89_RS01000	COG1063	alcohol dehydrogenase
CTB89_RS01010	COG1063	alcohol dehydrogenase
CTB89_RS01015	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CTB89_RS01020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CTB89_RS01030	COG1063	alcohol dehydrogenase
CTB89_RS01035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CTB89_RS01085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTB89_RS01095	COG1263	PTS System
CTB89_RS01095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTB89_RS01095	COG2190	(PTS) system
CTB89_RS01100	COG2723	6-phospho-beta-galactosidase activity
CTB89_RS01110	COG2226	methyltransferase
CTB89_RS01135	COG1609	Transcriptional regulator
CTB89_RS01160	COG1131	(ABC) transporter
CTB89_RS01180	COG3942	CHAP domain
CTB89_RS01180	COG1388	LysM domain
CTB89_RS01295	COG1114	Component of the transport system for branched-chain amino acids
CTB89_RS01305	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CTB89_RS01315	COG0577	efflux transmembrane transporter activity
CTB89_RS01345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTB89_RS01350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTB89_RS01375	COG3314	Sporulation integral membrane protein YlbJ
CTB89_RS01400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTB89_RS01430	COG3037	sugar-specific permease SgaT UlaA
CTB89_RS01440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTB89_RS01445	COG3711	transcriptional antiterminator
CTB89_RS01470	COG2271	Major facilitator Superfamily
CTB89_RS01475	COG0346	lactoylglutathione lyase activity
CTB89_RS01480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTB89_RS01485	COG0431	NADPH-dependent FMN reductase
CTB89_RS01500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTB89_RS01505	COG2822	iron ion transport
CTB89_RS01515	COG0672	)-iron permease
CTB89_RS01525	COG0805	protein transport
CTB89_RS01530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CTB89_RS01540	COG1476	TRANSCRIPTIONal
CTB89_RS01550	COG1131	(ABC) transporter
CTB89_RS01580	COG0646	methionine synthase
CTB89_RS01580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTB89_RS01585	COG0626	cystathionine gamma-synthase activity
CTB89_RS01590	COG0626	cystathionine gamma-synthase activity
CTB89_RS01600	COG1475	DNA binding
CTB89_RS01605	COG0668	transmembrane transport
CTB89_RS01610	COG4481	Protein conserved in bacteria
CTB89_RS01615	COG0012	GTP binding
CTB89_RS01650	COG4974	Belongs to the 'phage' integrase family
CTB89_RS01730	COG1823	symporter activity
CTB89_RS01765	COG2233	PERMEase
CTB89_RS01830	COG1683	Conserved Protein
CTB89_RS01840	COG3759	membrane
CTB89_RS02000	COG0523	cobalamin synthesis protein
CTB89_RS02025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTB89_RS02035	COG5609	conserved protein (DUF2294)
CTB89_RS02050	COG1647	Serine aminopeptidase, S33
CTB89_RS02055	COG0733	neurotransmitter:sodium symporter activity
CTB89_RS02060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTB89_RS02065	COG0626	cystathionine gamma-synthase activity
CTB89_RS02075	COG2011	ABC-type metal ion transport system permease component
CTB89_RS02080	COG1464	Belongs to the NlpA lipoprotein family
CTB89_RS02115	COG0583	DNA-binding transcription factor activity
CTB89_RS02120	COG0069	glutamate synthase activity
CTB89_RS02120	COG0070	glutamate synthase
CTB89_RS02120	COG0067	glutamate synthase
CTB89_RS02125	COG0493	'glutamate synthase
CTB89_RS02135	COG1263	PTS System
CTB89_RS02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTB89_RS02140	COG0366	Alpha amylase catalytic
CTB89_RS02145	COG2188	Transcriptional regulator
CTB89_RS02165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTB89_RS02200	COG1982	Orn Lys Arg decarboxylase major
CTB89_RS02210	COG3870	Protein conserved in bacteria
CTB89_RS02215	COG0470	DNA polymerase III
CTB89_RS02220	COG1774	PSP1 C-terminal conserved region
CTB89_RS02230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CTB89_RS02240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CTB89_RS02250	COG0084	hydrolase, TatD family'
CTB89_RS02255	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CTB89_RS02265	COG4466	Protein conserved in bacteria
CTB89_RS02275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTB89_RS02280	COG0251	oxidation-reduction process
CTB89_RS02300	COG3871	stress protein (general stress protein 26)
CTB89_RS02315	COG1263	PTS System
CTB89_RS02315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTB89_RS02330	COG1511	domain protein
CTB89_RS02360	COG0604	alcohol dehydrogenase
CTB89_RS02380	COG1620	l-lactate permease
CTB89_RS02395	COG1131	(ABC) transporter
CTB89_RS02465	COG2814	Major facilitator Superfamily
CTB89_RS02475	COG1566	PFAM secretion protein HlyD family protein
CTB89_RS02480	COG2814	Major facilitator Superfamily
CTB89_RS02490	COG0657	acetylesterase activity
CTB89_RS02505	COG0598	Magnesium transport protein CorA
CTB89_RS02515	COG0786	glutamate:sodium symporter activity
CTB89_RS02530	COG3152	Membrane
CTB89_RS02535	COG4152	abc transporter atp-binding protein
CTB89_RS02540	COG1668	transmembrane transport
CTB89_RS02560	COG2258	MOSC domain
CTB89_RS02580	COG0583	DNA-binding transcription factor activity
CTB89_RS02595	COG1473	amidohydrolase
CTB89_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
CTB89_RS02620	COG1737	Transcriptional regulator
CTB89_RS02625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTB89_RS02625	COG1263	PTS System
CTB89_RS02635	COG0385	Bile acid
CTB89_RS02640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTB89_RS02780	COG2244	polysaccharide biosynthetic process
CTB89_RS02785	COG3956	TIGRFAM MazG family protein
CTB89_RS02790	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTB89_RS02800	COG1098	S1 RNA binding domain
CTB89_RS02815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTB89_RS02840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTB89_RS02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTB89_RS02950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTB89_RS02960	COG3880	PFAM UvrB UvrC protein
CTB89_RS02975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CTB89_RS02980	COG4956	integral membrane protein (PIN domain superfamily)
CTB89_RS03005	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CTB89_RS03065	COG2813	Specifically methylates the guanine in position
CTB89_RS03105	COG1473	amidohydrolase
CTB89_RS03135	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CTB89_RS03140	COG1428	Deoxynucleoside kinase
CTB89_RS03145	COG1428	Deoxynucleoside kinase
CTB89_RS03155	COG0561	phosphatase activity
CTB89_RS03200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CTB89_RS03315	COG0095	Lipoate-protein ligase
CTB89_RS03320	COG0083	homoserine kinase activity
CTB89_RS03340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTB89_RS03400	COG0667	Aldo Keto reductase
CTB89_RS03405	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTB89_RS03415	COG1078	dGTPase activity
CTB89_RS03445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTB89_RS03450	COG4139	cobalamin transport
CTB89_RS03500	COG4974	Belongs to the 'phage' integrase family
CTB89_RS03545	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTB89_RS03550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTB89_RS03555	COG1121	(ABC) transporter
CTB89_RS03560	COG1321	iron dependent repressor
CTB89_RS03570	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CTB89_RS03580	COG1682	transport, permease protein
CTB89_RS03585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CTB89_RS03595	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CTB89_RS03600	COG1686	Belongs to the peptidase S11 family
CTB89_RS03605	COG1132	(ABC) transporter
CTB89_RS03610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTB89_RS03690	COG5632	N-Acetylmuramoyl-L-alanine amidase
CTB89_RS03690	COG1388	LysM domain
CTB89_RS03710	COG1388	LysM domain
CTB89_RS03710	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTB89_RS03750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CTB89_RS03755	COG1120	ATPase activity
CTB89_RS03760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTB89_RS03765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTB89_RS03770	COG2376	Dihydroxyacetone kinase
CTB89_RS03780	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CTB89_RS03790	COG3949	Membrane
CTB89_RS03815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTB89_RS03830	COG1136	(ABC) transporter
CTB89_RS03835	COG0577	efflux transmembrane transporter activity
CTB89_RS03840	COG1392	Phosphate transport regulator
CTB89_RS03845	COG0306	phosphate transporter
CTB89_RS03850	COG3942	CHAP domain
CTB89_RS03850	COG1388	LysM domain
CTB89_RS03860	COG4977	sequence-specific DNA binding
CTB89_RS03860	COG1917	Cupin 2, conserved barrel domain protein
CTB89_RS03890	COG0583	DNA-binding transcription factor activity
CTB89_RS03900	COG2814	Major facilitator Superfamily
CTB89_RS03905	COG2839	Protein conserved in bacteria
CTB89_RS03935	COG1611	Belongs to the LOG family
CTB89_RS03955	COG4988	ABC transporter
CTB89_RS03960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CTB89_RS03970	COG0523	cobalamin synthesis protein
CTB89_RS03975	COG4989	oxidoreductase activity
CTB89_RS03985	COG0471	metal ion transport
CTB89_RS03990	COG0415	Belongs to the DNA photolyase family
CTB89_RS04020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTB89_RS04025	COG1349	DNA-binding transcription factor activity
CTB89_RS04030	COG1105	Belongs to the carbohydrate kinase PfkB family
CTB89_RS04035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTB89_RS04035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTB89_RS04035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTB89_RS04040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CTB89_RS04045	COG1253	flavin adenine dinucleotide binding
CTB89_RS04050	COG0656	L-ascorbic acid biosynthetic process
CTB89_RS04055	COG0463	Glycosyl transferase, family 2
CTB89_RS04090	COG0720	synthase
CTB89_RS04100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTB89_RS04100	COG0512	Glutamine amidotransferase of anthranilate synthase
CTB89_RS04105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTB89_RS04135	COG0488	(ABC) transporter
CTB89_RS04140	COG0514	ATP-dependent DNA helicase (RecQ)
CTB89_RS04145	COG1125	glycine betaine transport
CTB89_RS04145	COG0517	IMP dehydrogenase activity
CTB89_RS04150	COG1174	glycine betaine transport
CTB89_RS04185	COG3104	oligopeptide transport
CTB89_RS04215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTB89_RS04220	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTB89_RS04230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTB89_RS04235	COG4605	iron ion homeostasis
CTB89_RS04240	COG4604	ABC transporter, ATP-binding protein
CTB89_RS04245	COG4607	ABC-type enterochelin transport system periplasmic component
CTB89_RS04300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTB89_RS04305	COG1739	Uncharacterized protein family UPF0029
CTB89_RS04315	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CTB89_RS04320	COG1040	competence protein
CTB89_RS04350	COG1388	LysM domain
CTB89_RS04350	COG3942	CHAP domain
CTB89_RS04405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CTB89_RS04425	COG0281	malic enzyme
CTB89_RS04480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CTB89_RS04485	COG1647	Serine aminopeptidase, S33
CTB89_RS04490	COG0557	exoribonuclease II activity
CTB89_RS04565	COG1278	Cold shock
CTB89_RS04605	COG0406	alpha-ribazole phosphatase activity
CTB89_RS04610	COG1279	arginine transmembrane transporter activity
CTB89_RS04635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTB89_RS04640	COG1393	Belongs to the ArsC family
CTB89_RS04655	COG3878	Protein conserved in bacteria
CTB89_RS04660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CTB89_RS04675	COG2011	ABC-type metal ion transport system permease component
CTB89_RS04680	COG1464	Belongs to the NlpA lipoprotein family
CTB89_RS04705	COG0396	ATPase activity
CTB89_RS04710	COG0719	Fe-S assembly protein
CTB89_RS04720	COG0822	iron-sulfur transferase activity
CTB89_RS04745	COG1253	flavin adenine dinucleotide binding
CTB89_RS04755	COG1801	Protein of unknown function DUF72
CTB89_RS04760	COG0730	response to heat
CTB89_RS04775	COG4470	Protein conserved in bacteria
CTB89_RS04785	COG2445	Protein of unknown function DUF86
CTB89_RS04815	COG1696	Membrane protein involved in D-alanine export
CTB89_RS04825	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CTB89_RS04830	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CTB89_RS04835	COG4837	Protein of unknown function (DUF1462)
CTB89_RS04840	COG1252	NADH dehydrogenase
CTB89_RS04850	COG0316	Belongs to the HesB IscA family
CTB89_RS04860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CTB89_RS04865	COG2056	Na+-H+ antiporter family
CTB89_RS04870	COG2050	protein possibly involved in aromatic compounds catabolism
CTB89_RS04925	COG1098	S1 RNA binding domain
CTB89_RS04930	COG1902	pentaerythritol trinitrate reductase activity
CTB89_RS04945	COG0584	glycerophosphoryl diester phosphodiesterase
CTB89_RS04970	COG0398	Pfam SNARE associated Golgi protein
CTB89_RS05010	COG0561	phosphatase activity
CTB89_RS05035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTB89_RS05050	COG1881	PFAM PEBP family protein
CTB89_RS05080	COG0601	transmembrane transport
CTB89_RS05085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTB89_RS05090	COG0444	Belongs to the ABC transporter superfamily
CTB89_RS05095	COG4608	Belongs to the ABC transporter superfamily
CTB89_RS05100	COG4166	transmembrane transport
CTB89_RS05105	COG0747	negative chemotaxis
CTB89_RS05110	COG0444	Belongs to the ABC transporter superfamily
CTB89_RS05120	COG0601	transmembrane transport
CTB89_RS05135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTB89_RS05160	COG1164	Oligoendopeptidase f
CTB89_RS05175	COG2346	COG2346, Truncated hemoglobins
CTB89_RS05190	COG2357	RelA SpoT domain protein
CTB89_RS05200	COG0564	pseudouridine synthase activity
CTB89_RS05205	COG2239	Acts as a magnesium transporter
CTB89_RS05210	COG0475	glutathione-regulated potassium exporter activity
CTB89_RS05210	COG0569	domain protein
CTB89_RS05220	COG0628	permease
CTB89_RS05225	COG1115	amino acid carrier protein
CTB89_RS05280	COG0861	Integral membrane protein TerC family
CTB89_RS05290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTB89_RS05295	COG0737	Belongs to the 5'-nucleotidase family
CTB89_RS05310	COG4903	ComK protein
CTB89_RS05325	COG4873	Protein conserved in bacteria
CTB89_RS05385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CTB89_RS05395	COG2314	TM2 domain
CTB89_RS05400	COG0456	acetyltransferase
CTB89_RS05405	COG1575	Belongs to the MenA family. Type 1 subfamily
CTB89_RS05415	COG1169	isochorismate synthase
CTB89_RS05425	COG2267	carboxylic ester hydrolase activity
CTB89_RS05450	COG0436	Aminotransferase
CTB89_RS05455	COG3594	Acyltransferase
CTB89_RS05485	COG1316	TRANSCRIPTIONal
CTB89_RS05530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CTB89_RS05545	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTB89_RS05590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CTB89_RS05595	COG4172	Belongs to the ABC transporter superfamily
CTB89_RS05600	COG4721	ABC-type cobalt transport system, permease component
CTB89_RS05620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CTB89_RS05640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTB89_RS05645	COG1271	oxidase subunit
CTB89_RS05650	COG1294	oxidase, subunit
CTB89_RS05655	COG0569	domain protein
CTB89_RS05720	COG1176	ABC-type spermidine putrescine transport system, permease component I
CTB89_RS05725	COG1177	transmembrane transport
CTB89_RS05730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CTB89_RS05755	COG0483	inositol monophosphate 1-phosphatase activity
CTB89_RS05765	COG1217	gtp-binding protein TYPA
CTB89_RS05775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CTB89_RS05785	COG0772	Belongs to the SEDS family
CTB89_RS05820	COG3679	Belongs to the UPF0342 family
CTB89_RS05840	COG0742	ribosomal rna small subunit methyltransferase
CTB89_RS05900	COG4509	Sortase family
CTB89_RS05915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTB89_RS05945	COG1796	DNA polymerase
CTB89_RS05945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CTB89_RS05970	COG2009	succinate dehydrogenase
CTB89_RS05975	COG1053	succinate dehydrogenase
CTB89_RS05980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTB89_RS06095	COG1288	antiporter activity
CTB89_RS06130	COG1011	Hydrolase
CTB89_RS06155	COG4839	cell division protein FtsL
CTB89_RS06160	COG0768	penicillin binding
CTB89_RS06175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTB89_RS06180	COG0849	cell division
CTB89_RS06195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CTB89_RS06205	COG0762	integral membrane protein
CTB89_RS06210	COG2302	S4 RNA-binding domain
CTB89_RS06215	COG3599	regulation of cell shape
CTB89_RS06225	COG2514	catechol 2,3-dioxygenase activity
CTB89_RS06250	COG0564	pseudouridine synthase activity
CTB89_RS06260	COG2233	PERMEase
CTB89_RS06305	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CTB89_RS06320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTB89_RS06325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTB89_RS06335	COG2314	TM2 domain
CTB89_RS06350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CTB89_RS06350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CTB89_RS06360	COG0631	protein serine/threonine phosphatase activity
CTB89_RS06375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTB89_RS06390	COG1302	Protein conserved in bacteria
CTB89_RS06440	COG1196	nuclear chromosome segregation
CTB89_RS06445	COG0552	protein localization to endoplasmic reticulum
CTB89_RS06455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTB89_RS06510	COG2348	transferase activity, transferring amino-acyl groups
CTB89_RS06515	COG0758	DNA mediated transformation
CTB89_RS06615	COG0195	Participates in both transcription termination and antitermination
CTB89_RS06620	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CTB89_RS06645	COG0196	riboflavin kinase activity
CTB89_RS06675	COG2188	Transcriptional regulator
CTB89_RS06680	COG0612	Peptidase, M16
CTB89_RS06685	COG0612	Peptidase, M16
CTB89_RS06690	COG0300	oxidoreductase activity
CTB89_RS06710	COG1058	Belongs to the CinA family
CTB89_RS06710	COG1546	Belongs to the CinA family
CTB89_RS06730	COG1692	metallophosphoesterase
CTB89_RS06735	COG0674	pyruvate-flavodoxin oxidoreductase activity
CTB89_RS06735	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CTB89_RS06740	COG1013	pyruvate-flavodoxin oxidoreductase activity
CTB89_RS06775	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CTB89_RS06785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTB89_RS06810	COG1923	regulation of RNA biosynthetic process
CTB89_RS06820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTB89_RS06825	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CTB89_RS06830	COG0789	Transcriptional regulator
CTB89_RS06955	COG1525	nuclease
CTB89_RS06970	COG0527	aspartate kinase activity
CTB89_RS06975	COG0460	homoserine dehydrogenase
CTB89_RS06980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTB89_RS07005	COG0833	amino acid
CTB89_RS07035	COG2340	Cysteine-rich secretory protein family
CTB89_RS07070	COG4846	Membrane protein involved in cytochrome C biogenesis
CTB89_RS07090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTB89_RS07100	COG0824	Thioesterase
CTB89_RS07130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CTB89_RS07140	COG1115	amino acid carrier protein
CTB89_RS07155	COG0628	permease
CTB89_RS07180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTB89_RS07190	COG1363	Peptidase, m42
CTB89_RS07195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTB89_RS07200	COG0512	Glutamine amidotransferase of anthranilate synthase
CTB89_RS07240	COG0561	phosphatase activity
CTB89_RS07285	COG0704	Plays a role in the regulation of phosphate uptake
CTB89_RS07295	COG0581	inorganic phosphate transmembrane transporter activity
CTB89_RS07300	COG0573	inorganic phosphate transmembrane transporter activity
CTB89_RS07315	COG0488	(ABC) transporter
CTB89_RS07325	COG0527	aspartate kinase activity
CTB89_RS07330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CTB89_RS07365	COG2808	Putative FMN-binding domain
CTB89_RS07410	COG4548	von Willebrand factor, type A
CTB89_RS07415	COG0714	Associated with various cellular activities
CTB89_RS07455	COG0671	phosphoesterase, PA-phosphatase related
CTB89_RS07530	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CTB89_RS07550	COG0531	amino acid
CTB89_RS07565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTB89_RS07570	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CTB89_RS07585	COG0116	Belongs to the methyltransferase superfamily
CTB89_RS07625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTB89_RS07625	COG4499	WXG100 protein secretion system (Wss), protein YukC
CTB89_RS07635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTB89_RS07640	COG3935	DnaD domain protein
CTB89_RS07665	COG0438	transferase activity, transferring glycosyl groups
CTB89_RS07670	COG1694	Mazg nucleotide pyrophosphohydrolase
CTB89_RS07675	COG2738	Putative neutral zinc metallopeptidase
CTB89_RS07680	COG4347	Protein of unknown function (DUF1405)
CTB89_RS07715	COG0142	geranyltranstransferase activity
CTB89_RS07785	COG0492	ferredoxin-NADP+ reductase activity
CTB89_RS07800	COG0514	ATP-dependent DNA helicase (RecQ)
CTB89_RS07810	COG1141	Ferredoxin
CTB89_RS07840	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTB89_RS07840	COG1388	LysM domain
CTB89_RS07890	COG5280	Phage tail tape measure protein TP901
CTB89_RS07890	COG3953	SLT domain
CTB89_RS08120	COG2176	DNA-directed DNA polymerase activity
CTB89_RS08135	COG0582	viral genome integration into host DNA
CTB89_RS08150	COG5002	protein histidine kinase activity
CTB89_RS08155	COG0745	RESPONSE REGULATOR receiver
CTB89_RS08160	COG1187	pseudouridine synthase activity
CTB89_RS08185	COG0735	belongs to the Fur family
CTB89_RS08190	COG0494	nUDIX hydrolase
CTB89_RS08195	COG0667	Aldo Keto reductase
CTB89_RS08205	COG4221	oxidoreductase activity
CTB89_RS08220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CTB89_RS08230	COG0366	Alpha amylase catalytic
CTB89_RS08235	COG1609	Transcriptional regulator
CTB89_RS08255	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTB89_RS08265	COG4129	membrane
CTB89_RS08275	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTB89_RS08280	COG0022	dehydrogenase e1 component
CTB89_RS08285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTB89_RS08290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTB89_RS08295	COG0497	DNA recombination
CTB89_RS08325	COG1302	Protein conserved in bacteria
CTB89_RS08330	COG0439	Biotin carboxylase
CTB89_RS08335	COG0511	ligase activity, forming carbon-carbon bonds
CTB89_RS08345	COG0006	proline dipeptidase activity
CTB89_RS08360	COG0095	Lipoate-protein ligase
CTB89_RS08365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTB89_RS08410	COG4537	Required for transformation and DNA binding
CTB89_RS08415	COG1459	type II secretion system
CTB89_RS08420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTB89_RS08425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTB89_RS08430	COG0011	TIGRFAM Protein of
CTB89_RS08435	COG1940	carbohydrate kinase activity
CTB89_RS08440	COG4483	Protein conserved in bacteria
CTB89_RS08450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTB89_RS08460	COG0768	penicillin binding
CTB89_RS08475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTB89_RS08480	COG1121	(ABC) transporter
CTB89_RS08490	COG0513	Belongs to the DEAD box helicase family
CTB89_RS08500	COG2384	SAM-dependent methyltransferase
CTB89_RS08520	COG0517	IMP dehydrogenase activity
CTB89_RS08540	COG0295	cytidine deaminase activity
CTB89_RS08555	COG1702	phosphate starvation-inducible protein PhoH
CTB89_RS08570	COG1030	water channel activity
CTB89_RS08580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CTB89_RS08585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTB89_RS08615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTB89_RS08635	COG1466	dna polymerase III delta subunit
CTB89_RS08640	COG2333	competence protein COMEC
CTB89_RS08640	COG0658	competence protein
CTB89_RS08645	COG2131	deaminase
CTB89_RS08650	COG2183	response to ionizing radiation
CTB89_RS08655	COG2226	methyltransferase
CTB89_RS08660	COG0799	negative regulation of ribosome biogenesis
CTB89_RS08665	COG1713	HD superfamily hydrolase involved in NAD metabolism
CTB89_RS08675	COG1534	Rna-binding protein
CTB89_RS08685	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CTB89_RS08690	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CTB89_RS08710	COG1914	H( )-stimulated, divalent metal cation uptake system
CTB89_RS08720	COG0439	Biotin carboxylase
CTB89_RS08725	COG0511	ligase activity, forming carbon-carbon bonds
CTB89_RS08730	COG1984	allophanate hydrolase subunit 2
CTB89_RS08735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CTB89_RS08750	COG0826	peptidase U32
CTB89_RS08755	COG0826	peptidase U32
CTB89_RS08785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTB89_RS08810	COG1104	cysteine desulfurase activity
CTB89_RS08815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTB89_RS08825	COG3237	CsbD-like
CTB89_RS08830	COG1959	2 iron, 2 sulfur cluster binding
CTB89_RS08835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTB89_RS08840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTB89_RS08885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTB89_RS08885	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CTB89_RS08890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTB89_RS08890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTB89_RS08895	COG1862	Preprotein translocase
CTB89_RS08935	COG2868	ribosomal protein
CTB89_RS09015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CTB89_RS09025	COG0285	dihydrofolate synthase activity
CTB89_RS09035	COG2818	Glycosylase
CTB89_RS09070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CTB89_RS09105	COG4112	unkown
CTB89_RS09130	COG0833	amino acid
CTB89_RS09145	COG1484	DNA-dependent DNA replication
CTB89_RS09175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTB89_RS09175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTB89_RS09185	COG5002	protein histidine kinase activity
CTB89_RS09190	COG0745	RESPONSE REGULATOR receiver
CTB89_RS09205	COG0372	Belongs to the citrate synthase family
CTB89_RS09210	COG1113	amino acid transport
CTB89_RS09235	COG0281	malic enzyme
CTB89_RS09245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CTB89_RS09250	COG4109	DRTGG domain
CTB89_RS09295	COG0827	DNA restriction-modification system
CTB89_RS09305	COG0730	response to heat
CTB89_RS09315	COG1104	cysteine desulfurase activity
CTB89_RS09325	COG1956	GAF domain-containing protein
CTB89_RS09345	COG0584	glycerophosphoryl diester phosphodiesterase
CTB89_RS09350	COG1764	response to oxidative stress
CTB89_RS09355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTB89_RS09360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTB89_RS09375	COG1263	PTS System
CTB89_RS09375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTB89_RS09380	COG0204	Acyl-transferase
CTB89_RS09385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTB89_RS09420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTB89_RS09425	COG0454	-acetyltransferase
CTB89_RS09445	COG1605	Chorismate mutase
CTB89_RS09445	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CTB89_RS09470	COG1674	ftsk spoiiie
CTB89_RS09475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTB89_RS09485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTB89_RS09490	COG1363	Peptidase, m42
CTB89_RS09500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTB89_RS09510	COG0510	thiamine kinase activity
CTB89_RS09530	COG1187	pseudouridine synthase activity
CTB89_RS09535	COG2244	polysaccharide biosynthetic process
CTB89_RS09540	COG2081	HI0933 family
CTB89_RS09560	COG2814	Major facilitator Superfamily
CTB89_RS09570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CTB89_RS09585	COG2267	carboxylic ester hydrolase activity
CTB89_RS09620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTB89_RS09620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTB89_RS09645	COG5632	N-Acetylmuramoyl-L-alanine amidase
CTB89_RS09645	COG4193	domain, Protein
CTB89_RS09645	COG3266	domain, Protein
CTB89_RS09680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTB89_RS09700	COG0656	L-ascorbic acid biosynthetic process
CTB89_RS09720	COG1506	peptidase
CTB89_RS09725	COG2816	NAD+ diphosphatase activity
CTB89_RS09825	COG5492	domain, Protein
CTB89_RS09995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CTB89_RS10025	COG1131	(ABC) transporter
CTB89_RS10030	COG0537	adenosine 5'-monophosphoramidase activity
CTB89_RS10065	COG0420	3'-5' exonuclease activity
CTB89_RS10095	COG2197	response regulator
CTB89_RS10100	COG4585	Histidine kinase
CTB89_RS10100	COG2203	Gaf domain
CTB89_RS10105	COG0564	pseudouridine synthase activity
CTB89_RS10140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTB89_RS10145	COG1126	abc transporter atp-binding protein
CTB89_RS10150	COG0765	amino acid transport
CTB89_RS10315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTB89_RS10320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTB89_RS10330	COG4129	membrane
CTB89_RS10350	COG1194	a g-specific adenine glycosylase
CTB89_RS10355	COG1988	membrane-bound metal-dependent
CTB89_RS10370	COG1388	LysM domain
CTB89_RS10370	COG1134	teichoic acid transport
CTB89_RS10400	COG0535	radical SAM domain protein
CTB89_RS10405	COG1607	acyl-coa hydrolase
CTB89_RS10410	COG2309	aminopeptidase activity
CTB89_RS10430	COG1295	ribonuclease BN
CTB89_RS10550	COG4851	CamS sex pheromone cAM373 precursor
CTB89_RS10570	COG4496	protein, YerC YecD
CTB89_RS10610	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CTB89_RS10620	COG0077	Prephenate dehydratase
CTB89_RS10630	COG0471	metal ion transport
CTB89_RS10640	COG1335	isochorismatase
CTB89_RS10655	COG1012	belongs to the aldehyde dehydrogenase family
CTB89_RS10665	COG3682	Transcriptional regulator
CTB89_RS10695	COG4974	Belongs to the 'phage' integrase family
CTB89_RS10750	COG1131	(ABC) transporter
CTB89_RS10765	COG1725	Transcriptional regulator
CTB89_RS10815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTB89_RS10860	COG5484	DNA packaging
CTB89_RS10860	COG3728	DNA packaging
CTB89_RS10935	COG0582	viral genome integration into host DNA
CTB89_RS11000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTB89_RS11005	COG1621	beta-fructofuranosidase activity
CTB89_RS11010	COG1609	Transcriptional regulator
CTB89_RS11015	COG0004	ammonium transporteR
CTB89_RS11020	COG0425	Belongs to the sulfur carrier protein TusA family
CTB89_RS11035	COG0488	(ABC) transporter
CTB89_RS11045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CTB89_RS11060	COG0456	acetyltransferase
CTB89_RS11065	COG1214	PFAM Peptidase M22, glycoprotease
CTB89_RS11070	COG0802	atpase or kinase
CTB89_RS11085	COG0028	Belongs to the TPP enzyme family
CTB89_RS11170	COG2183	response to ionizing radiation
CTB89_RS11175	COG1191	sigma factor activity
CTB89_RS11185	COG1366	Belongs to the anti-sigma-factor antagonist family
CTB89_RS11190	COG2208	phosphoserine phosphatase activity
CTB89_RS11225	COG3428	Bacterial PH domain
CTB89_RS11255	COG2205	protein histidine kinase activity
CTB89_RS11260	COG0745	RESPONSE REGULATOR receiver
CTB89_RS11270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTB89_RS11280	COG0772	Belongs to the SEDS family
CTB89_RS11295	COG1937	Protein conserved in bacteria
CTB89_RS11305	COG1418	mRNA catabolic process
CTB89_RS11360	COG0629	single-stranded DNA binding
CTB89_RS11440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTB89_RS11465	COG0009	L-threonylcarbamoyladenylate synthase
CTB89_RS11470	COG2890	protein-(glutamine-N5) methyltransferase activity
CTB89_RS11495	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CTB89_RS11535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTB89_RS11585	COG0813	purine-nucleoside phosphorylase activity
CTB89_RS11590	COG0783	Belongs to the Dps family
CTB89_RS11610	COG1482	cell wall glycoprotein biosynthetic process
CTB89_RS11615	COG0702	epimerase
CTB89_RS11620	COG0640	Transcriptional regulator
CTB89_RS11670	COG0561	phosphatase activity
CTB89_RS11675	COG1119	ATPase activity
CTB89_RS11690	COG3711	transcriptional antiterminator
CTB89_RS11720	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CTB89_RS11780	COG0489	protein tyrosine kinase activity
CTB89_RS11785	COG2814	Major facilitator Superfamily
CTB89_RS11800	COG1272	protein, Hemolysin III
CTB89_RS11810	COG1988	membrane-bound metal-dependent
CTB89_RS11820	COG3314	Sporulation integral membrane protein YlbJ
CTB89_RS11825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTB89_RS11830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTB89_RS11835	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CTB89_RS11845	COG3457	Alanine racemase
CTB89_RS11850	COG4264	IucA IucC family
CTB89_RS11855	COG2814	Major facilitator Superfamily
CTB89_RS11880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTB89_RS11890	COG2130	NADP-dependent
CTB89_RS11955	COG0656	L-ascorbic acid biosynthetic process
CTB89_RS11960	COG0789	Transcriptional regulator
CTB89_RS11970	COG5492	domain, Protein
CTB89_RS11975	COG2378	regulation of single-species biofilm formation
CTB89_RS11980	COG0693	protein deglycase activity
CTB89_RS11990	COG3527	Alpha-acetolactate decarboxylase
CTB89_RS11995	COG0028	Belongs to the TPP enzyme family
CTB89_RS12080	COG0201	protein transport
CTB89_RS12195	COG2252	PERMEase
CTB89_RS12240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTB89_RS12300	COG1763	Mo-molybdopterin cofactor biosynthetic process
CTB89_RS12320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTB89_RS12325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTB89_RS12330	COG4149	molybdate abc transporter
CTB89_RS12335	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTB89_RS12350	COG1268	BioY protein
CTB89_RS12370	COG1960	acyl-CoA dehydrogenase activity
CTB89_RS12375	COG4413	Urea transporter
CTB89_RS12450	COG1757	Na H antiporter
CTB89_RS12465	COG3942	CHAP domain
CTB89_RS12515	COG0789	Transcriptional regulator
CTB89_RS12535	COG2181	nitrate reductase activity
CTB89_RS12545	COG1140	nitrate reductase beta subunit
CTB89_RS12550	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CTB89_RS12560	COG2146	nitrite reductase [NAD(P)H] activity
CTB89_RS12565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTB89_RS12575	COG0454	-acetyltransferase
CTB89_RS12580	COG2116	formate transmembrane transporter activity
CTB89_RS12595	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTB89_RS12595	COG3443	Belongs to the bacterial solute-binding protein 9 family
CTB89_RS12630	COG1126	abc transporter atp-binding protein
CTB89_RS12635	COG0765	amino acid transport
CTB89_RS12640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTB89_RS12645	COG2814	Major facilitator Superfamily
CTB89_RS12665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CTB89_RS12710	COG0156	8-amino-7-oxononanoate synthase activity
CTB89_RS12720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CTB89_RS12725	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CTB89_RS12740	COG1132	(ABC) transporter
CTB89_RS12745	COG2375	cellular response to nickel ion
CTB89_RS12745	COG1132	(ABC) transporter
CTB89_RS12760	COG1929	Belongs to the glycerate kinase type-1 family
CTB89_RS12770	COG2814	Major facilitator Superfamily
CTB89_RS12785	COG1408	metallophosphoesterase
CTB89_RS12790	COG1113	amino acid transport
CTB89_RS12805	COG0531	amino acid
CTB89_RS12830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CTB89_RS12840	COG1174	glycine betaine transport
CTB89_RS12850	COG1174	glycine betaine transport
CTB89_RS12870	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CTB89_RS12875	COG0531	amino acid
CTB89_RS12880	COG2272	Belongs to the type-B carboxylesterase lipase family
CTB89_RS12885	COG2814	Major facilitator Superfamily
CTB89_RS12890	COG0390	transport system, permease component
CTB89_RS12895	COG4619	ABC transporter
CTB89_RS12900	COG1363	Peptidase, m42
CTB89_RS12920	COG4808	Protein conserved in bacteria
CTB89_RS12925	COG0069	glutamate synthase activity
CTB89_RS12940	COG1124	(ABC) transporter
CTB89_RS12950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTB89_RS12955	COG0601	transmembrane transport
CTB89_RS12960	COG0747	negative chemotaxis
CTB89_RS12980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CTB89_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
CTB89_RS12990	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CTB89_RS12995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTB89_RS13090	COG0494	nUDIX hydrolase
CTB89_RS13150	COG1070	Carbohydrate kinase
CTB89_RS13155	COG1802	Transcriptional regulator
CTB89_RS13160	COG0789	Transcriptional regulator
CTB89_RS13165	COG2357	RelA SpoT domain protein
CTB89_RS13170	COG4876	unkown
CTB89_RS13185	COG2271	Major facilitator Superfamily
CTB89_RS13190	COG0586	Pfam SNARE associated Golgi protein
CTB89_RS13215	COG0400	carboxylic ester hydrolase activity
CTB89_RS13220	COG0346	lactoylglutathione lyase activity
CTB89_RS13225	COG1846	Transcriptional regulator
CTB89_RS13235	COG2514	catechol 2,3-dioxygenase activity
CTB89_RS13250	COG0561	phosphatase activity
CTB89_RS13255	COG1131	(ABC) transporter
CTB89_RS13265	COG3764	Sortase (surface protein transpeptidase)
CTB89_RS13285	COG1760	l-serine dehydratase
CTB89_RS13290	COG1760	l-serine dehydratase
CTB89_RS13305	COG0697	spore germination
CTB89_RS13310	COG0657	acetylesterase activity
CTB89_RS13335	COG0028	Belongs to the TPP enzyme family
CTB89_RS13350	COG0583	DNA-binding transcription factor activity
CTB89_RS13360	COG3942	CHAP domain
CTB89_RS13370	COG3425	synthase
CTB89_RS13380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTB89_RS13405	COG2409	Drug exporters of the RND superfamily
CTB89_RS13450	COG0436	Aminotransferase
CTB89_RS13555	COG0596	Alpha beta hydrolase
CTB89_RS13590	COG3001	Fructosamine kinase
CTB89_RS13595	COG0167	dihydroorotate dehydrogenase activity
CTB89_RS13650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CTB89_RS13655	COG3527	Alpha-acetolactate decarboxylase
CTB89_RS13670	COG0531	amino acid
CTB89_RS13700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTB89_RS13720	COG1012	belongs to the aldehyde dehydrogenase family
CTB89_RS13730	COG1510	regulation of RNA biosynthetic process
CTB89_RS13740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTB89_RS13765	COG2851	Citrate transporter
CTB89_RS13775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTB89_RS13785	COG0386	Belongs to the glutathione peroxidase family
CTB89_RS13810	COG1136	(ABC) transporter
CTB89_RS13815	COG2205	protein histidine kinase activity
CTB89_RS13820	COG0745	RESPONSE REGULATOR receiver
CTB89_RS13830	COG1785	Belongs to the alkaline phosphatase family
CTB89_RS13840	COG1846	Transcriptional regulator
CTB89_RS13885	COG1438	arginine binding
CTB89_RS13905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTB89_RS13905	COG3711	transcriptional antiterminator
CTB89_RS13910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTB89_RS13910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTB89_RS13910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTB89_RS13915	COG1482	cell wall glycoprotein biosynthetic process
CTB89_RS13925	COG3942	CHAP domain
CTB89_RS13925	COG1705	Flagellar rod assembly protein muramidase FlgJ
CTB89_RS13930	COG1535	isochorismatase
CTB89_RS13930	COG3433	isochorismatase activity
CTB89_RS13945	COG0438	transferase activity, transferring glycosyl groups
CTB89_RS13960	COG1073	alpha beta
CTB89_RS13980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTB89_RS14010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTB89_RS14105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTB89_RS14195	COG0471	metal ion transport
CTB89_RS14200	COG2962	Rard protein
CTB89_RS14210	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CTB89_RS14225	COG1136	(ABC) transporter
CTB89_RS14230	COG0577	efflux transmembrane transporter activity
CTB89_RS14265	COG1278	Cold shock
CTB89_RS14290	COG1475	DNA binding