locus-tag	class	description
HLB24_RS00030	COG2501	S4 domain
HLB24_RS00050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HLB24_RS00075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HLB24_RS00085	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HLB24_RS00095	COG0305	Participates in initiation and elongation during chromosome replication
HLB24_RS00125	COG4863	YycH protein
HLB24_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HLB24_RS00140	COG0737	Belongs to the 5'-nucleotidase family
HLB24_RS00165	COG0584	glycerophosphoryl diester phosphodiesterase
HLB24_RS00170	COG2030	dehydratase
HLB24_RS00285	COG1522	sequence-specific DNA binding
HLB24_RS00290	COG0456	acetyltransferase
HLB24_RS00315	COG0655	NAD(P)H dehydrogenase (quinone) activity
HLB24_RS00350	COG0823	Involved in the tonB-independent uptake of proteins
HLB24_RS00365	COG1473	amidohydrolase
HLB24_RS00375	COG1283	sodium-dependent phosphate transmembrane transporter activity
HLB24_RS00380	COG4716	Myosin-crossreactive antigen
HLB24_RS00385	COG0697	spore germination
HLB24_RS00400	COG1620	l-lactate permease
HLB24_RS00420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLB24_RS00425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLB24_RS00430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HLB24_RS00440	COG2423	ornithine cyclodeaminase activity
HLB24_RS00445	COG4264	IucA IucC family
HLB24_RS00450	COG2814	Major facilitator Superfamily
HLB24_RS00455	COG4264	IucA IucC family
HLB24_RS00460	COG4264	IucA IucC family
HLB24_RS00470	COG0019	diaminopimelate decarboxylase activity
HLB24_RS00475	COG1475	DNA binding
HLB24_RS00500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HLB24_RS00505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HLB24_RS00510	COG0438	transferase activity, transferring glycosyl groups
HLB24_RS00535	COG0813	purine-nucleoside phosphorylase activity
HLB24_RS00540	COG2814	Major facilitator Superfamily
HLB24_RS00560	COG3639	organic phosphonate transmembrane transporter activity
HLB24_RS00580	COG0737	Belongs to the 5'-nucleotidase family
HLB24_RS00595	COG1454	alcohol dehydrogenase
HLB24_RS00595	COG1012	belongs to the aldehyde dehydrogenase family
HLB24_RS00620	COG1086	Polysaccharide biosynthesis protein
HLB24_RS00630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HLB24_RS00660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HLB24_RS00670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HLB24_RS00675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HLB24_RS00685	COG2832	Protein of unknown function (DUF454)
HLB24_RS00720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HLB24_RS00725	COG1960	acyl-CoA dehydrogenase activity
HLB24_RS00745	COG3477	response to acidic pH
HLB24_RS00770	COG1114	Component of the transport system for branched-chain amino acids
HLB24_RS00775	COG1335	isochorismatase
HLB24_RS00780	COG3961	Belongs to the TPP enzyme family
HLB24_RS00810	COG1737	Transcriptional regulator
HLB24_RS00840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLB24_RS00850	COG0405	Gamma-glutamyltransferase
HLB24_RS00870	COG3842	ATPase activity
HLB24_RS00880	COG1175	transmembrane transport
HLB24_RS00885	COG3833	ABC-type maltose transport systems, permease component
HLB24_RS00890	COG0673	inositol 2-dehydrogenase activity
HLB24_RS00895	COG0673	inositol 2-dehydrogenase activity
HLB24_RS00905	COG1755	Isoprenylcysteine carboxyl methyltransferase
HLB24_RS00960	COG0183	Belongs to the thiolase family
HLB24_RS00970	COG1960	acyl-CoA dehydrogenase activity
HLB24_RS00975	COG0318	PFAM AMP-dependent synthetase and ligase
HLB24_RS00990	COG0747	negative chemotaxis
HLB24_RS00995	COG3189	MarR family transcriptional regulator
HLB24_RS01020	COG1263	PTS System
HLB24_RS01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HLB24_RS01020	COG2190	(PTS) system
HLB24_RS01025	COG1957	nucleoside hydrolase
HLB24_RS01045	COG3414	Phosphotransferase system galactitol-specific IIB component
HLB24_RS01050	COG3775	system Galactitol-specific IIC component
HLB24_RS01055	COG1063	alcohol dehydrogenase
HLB24_RS01065	COG1063	alcohol dehydrogenase
HLB24_RS01075	COG1063	alcohol dehydrogenase
HLB24_RS01080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLB24_RS01085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLB24_RS01095	COG1063	alcohol dehydrogenase
HLB24_RS01100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLB24_RS01135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HLB24_RS01140	COG2190	(PTS) system
HLB24_RS01140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HLB24_RS01140	COG1263	PTS System
HLB24_RS01145	COG2723	6-phospho-beta-galactosidase activity
HLB24_RS01150	COG2226	methyltransferase
HLB24_RS01205	COG1131	(ABC) transporter
HLB24_RS01225	COG3942	CHAP domain
HLB24_RS01225	COG1388	LysM domain
HLB24_RS01350	COG1114	Component of the transport system for branched-chain amino acids
HLB24_RS01355	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HLB24_RS01360	COG0577	efflux transmembrane transporter activity
HLB24_RS01385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLB24_RS01390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLB24_RS01440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLB24_RS01465	COG3037	sugar-specific permease SgaT UlaA
HLB24_RS01475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HLB24_RS01480	COG3711	transcriptional antiterminator
HLB24_RS01500	COG2271	Major facilitator Superfamily
HLB24_RS01505	COG0346	lactoylglutathione lyase activity
HLB24_RS01510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLB24_RS01515	COG0431	NADPH-dependent FMN reductase
HLB24_RS01525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLB24_RS01530	COG2822	iron ion transport
HLB24_RS01540	COG0672	)-iron permease
HLB24_RS01545	COG0805	protein transport
HLB24_RS01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLB24_RS01560	COG1476	TRANSCRIPTIONal
HLB24_RS01570	COG1131	(ABC) transporter
HLB24_RS01600	COG0646	methionine synthase
HLB24_RS01600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HLB24_RS01605	COG0626	cystathionine gamma-synthase activity
HLB24_RS01610	COG0626	cystathionine gamma-synthase activity
HLB24_RS01615	COG1475	DNA binding
HLB24_RS01620	COG0668	transmembrane transport
HLB24_RS01625	COG4481	Protein conserved in bacteria
HLB24_RS01630	COG0012	GTP binding
HLB24_RS01740	COG1823	symporter activity
HLB24_RS01770	COG2233	PERMEase
HLB24_RS01820	COG1683	Conserved Protein
HLB24_RS01830	COG3759	membrane
HLB24_RS01990	COG0523	cobalamin synthesis protein
HLB24_RS02015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HLB24_RS02025	COG5609	conserved protein (DUF2294)
HLB24_RS02040	COG1647	Serine aminopeptidase, S33
HLB24_RS02045	COG0733	neurotransmitter:sodium symporter activity
HLB24_RS02050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HLB24_RS02055	COG0626	cystathionine gamma-synthase activity
HLB24_RS02065	COG2011	ABC-type metal ion transport system permease component
HLB24_RS02070	COG1464	Belongs to the NlpA lipoprotein family
HLB24_RS02085	COG0494	nUDIX hydrolase
HLB24_RS02105	COG0583	DNA-binding transcription factor activity
HLB24_RS02110	COG0067	glutamate synthase
HLB24_RS02110	COG0069	glutamate synthase activity
HLB24_RS02110	COG0070	glutamate synthase
HLB24_RS02115	COG0493	'glutamate synthase
HLB24_RS02125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HLB24_RS02125	COG1263	PTS System
HLB24_RS02130	COG0366	Alpha amylase catalytic
HLB24_RS02135	COG2188	Transcriptional regulator
HLB24_RS02155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLB24_RS02190	COG1982	Orn Lys Arg decarboxylase major
HLB24_RS02200	COG3870	Protein conserved in bacteria
HLB24_RS02205	COG0470	DNA polymerase III
HLB24_RS02210	COG1774	PSP1 C-terminal conserved region
HLB24_RS02230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLB24_RS02240	COG0084	hydrolase, TatD family'
HLB24_RS02245	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLB24_RS02255	COG4466	Protein conserved in bacteria
HLB24_RS02265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLB24_RS02270	COG0251	oxidation-reduction process
HLB24_RS02315	COG2244	polysaccharide biosynthetic process
HLB24_RS02320	COG3956	TIGRFAM MazG family protein
HLB24_RS02325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HLB24_RS02335	COG1098	S1 RNA binding domain
HLB24_RS02350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLB24_RS02375	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLB24_RS02470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HLB24_RS02485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLB24_RS02495	COG3880	PFAM UvrB UvrC protein
HLB24_RS02510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLB24_RS02515	COG4956	integral membrane protein (PIN domain superfamily)
HLB24_RS02535	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLB24_RS02590	COG2813	Specifically methylates the guanine in position
HLB24_RS02630	COG1473	amidohydrolase
HLB24_RS02660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HLB24_RS02665	COG1428	Deoxynucleoside kinase
HLB24_RS02670	COG1428	Deoxynucleoside kinase
HLB24_RS02680	COG0561	phosphatase activity
HLB24_RS02725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HLB24_RS02835	COG0095	Lipoate-protein ligase
HLB24_RS02840	COG0083	homoserine kinase activity
HLB24_RS02860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HLB24_RS02910	COG0667	Aldo Keto reductase
HLB24_RS02915	COG0655	NAD(P)H dehydrogenase (quinone) activity
HLB24_RS02925	COG1078	dGTPase activity
HLB24_RS02955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HLB24_RS02960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLB24_RS03010	COG4974	Belongs to the 'phage' integrase family
HLB24_RS03055	COG0803	Belongs to the bacterial solute-binding protein 9 family
HLB24_RS03060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HLB24_RS03065	COG1121	(ABC) transporter
HLB24_RS03070	COG1321	iron dependent repressor
HLB24_RS03080	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HLB24_RS03090	COG1682	transport, permease protein
HLB24_RS03095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLB24_RS03105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HLB24_RS03110	COG1686	Belongs to the peptidase S11 family
HLB24_RS03115	COG1132	(ABC) transporter
HLB24_RS03120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLB24_RS03130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLB24_RS03135	COG1120	ATPase activity
HLB24_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLB24_RS03145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLB24_RS03150	COG2376	Dihydroxyacetone kinase
HLB24_RS03160	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HLB24_RS03170	COG3949	Membrane
HLB24_RS03190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HLB24_RS03205	COG1136	(ABC) transporter
HLB24_RS03210	COG0577	efflux transmembrane transporter activity
HLB24_RS03215	COG1392	Phosphate transport regulator
HLB24_RS03220	COG0306	phosphate transporter
HLB24_RS03225	COG3942	CHAP domain
HLB24_RS03225	COG1388	LysM domain
HLB24_RS03235	COG1917	Cupin 2, conserved barrel domain protein
HLB24_RS03235	COG4977	sequence-specific DNA binding
HLB24_RS03265	COG0583	DNA-binding transcription factor activity
HLB24_RS03275	COG2839	Protein conserved in bacteria
HLB24_RS03305	COG1611	Belongs to the LOG family
HLB24_RS03325	COG4988	ABC transporter
HLB24_RS03330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLB24_RS03340	COG0523	cobalamin synthesis protein
HLB24_RS03345	COG4989	oxidoreductase activity
HLB24_RS03355	COG0471	metal ion transport
HLB24_RS03390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLB24_RS03395	COG1349	DNA-binding transcription factor activity
HLB24_RS03400	COG1105	Belongs to the carbohydrate kinase PfkB family
HLB24_RS03405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HLB24_RS03405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HLB24_RS03405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HLB24_RS03410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLB24_RS03415	COG1253	flavin adenine dinucleotide binding
HLB24_RS03420	COG0656	L-ascorbic acid biosynthetic process
HLB24_RS03425	COG0463	Glycosyl transferase, family 2
HLB24_RS03460	COG0720	synthase
HLB24_RS03470	COG0512	Glutamine amidotransferase of anthranilate synthase
HLB24_RS03470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLB24_RS03475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLB24_RS03505	COG0488	(ABC) transporter
HLB24_RS03510	COG0514	ATP-dependent DNA helicase (RecQ)
HLB24_RS03515	COG1125	glycine betaine transport
HLB24_RS03515	COG0517	IMP dehydrogenase activity
HLB24_RS03520	COG1174	glycine betaine transport
HLB24_RS03545	COG3104	oligopeptide transport
HLB24_RS03565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLB24_RS03570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLB24_RS03580	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLB24_RS03585	COG4605	iron ion homeostasis
HLB24_RS03590	COG4604	ABC transporter, ATP-binding protein
HLB24_RS03595	COG4607	ABC-type enterochelin transport system periplasmic component
HLB24_RS03650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLB24_RS03655	COG1739	Uncharacterized protein family UPF0029
HLB24_RS03665	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HLB24_RS03670	COG1040	competence protein
HLB24_RS03700	COG3942	CHAP domain
HLB24_RS03700	COG1388	LysM domain
HLB24_RS03755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HLB24_RS03770	COG0281	malic enzyme
HLB24_RS03820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HLB24_RS03825	COG1647	Serine aminopeptidase, S33
HLB24_RS03830	COG0557	exoribonuclease II activity
HLB24_RS03895	COG1278	Cold shock
HLB24_RS03935	COG0406	alpha-ribazole phosphatase activity
HLB24_RS03940	COG1279	arginine transmembrane transporter activity
HLB24_RS03965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HLB24_RS03970	COG1393	Belongs to the ArsC family
HLB24_RS03980	COG3878	Protein conserved in bacteria
HLB24_RS03985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLB24_RS04000	COG2011	ABC-type metal ion transport system permease component
HLB24_RS04005	COG1464	Belongs to the NlpA lipoprotein family
HLB24_RS04010	COG0582	viral genome integration into host DNA
HLB24_RS04115	COG5484	DNA packaging
HLB24_RS04115	COG3728	DNA packaging
HLB24_RS04155	COG0396	ATPase activity
HLB24_RS04160	COG0719	Fe-S assembly protein
HLB24_RS04170	COG0822	iron-sulfur transferase activity
HLB24_RS04190	COG1253	flavin adenine dinucleotide binding
HLB24_RS04205	COG1801	Protein of unknown function DUF72
HLB24_RS04210	COG0730	response to heat
HLB24_RS04225	COG4470	Protein conserved in bacteria
HLB24_RS04235	COG2445	Protein of unknown function DUF86
HLB24_RS04265	COG1696	Membrane protein involved in D-alanine export
HLB24_RS04275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLB24_RS04280	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HLB24_RS04285	COG4837	Protein of unknown function (DUF1462)
HLB24_RS04290	COG1252	NADH dehydrogenase
HLB24_RS04300	COG0316	Belongs to the HesB IscA family
HLB24_RS04310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HLB24_RS04315	COG2056	Na+-H+ antiporter family
HLB24_RS04320	COG2050	protein possibly involved in aromatic compounds catabolism
HLB24_RS04375	COG1098	S1 RNA binding domain
HLB24_RS04380	COG1902	pentaerythritol trinitrate reductase activity
HLB24_RS04395	COG0584	glycerophosphoryl diester phosphodiesterase
HLB24_RS04415	COG0398	Pfam SNARE associated Golgi protein
HLB24_RS04455	COG0561	phosphatase activity
HLB24_RS04480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HLB24_RS04495	COG1881	PFAM PEBP family protein
HLB24_RS04525	COG0601	transmembrane transport
HLB24_RS04530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLB24_RS04535	COG0444	Belongs to the ABC transporter superfamily
HLB24_RS04540	COG4608	Belongs to the ABC transporter superfamily
HLB24_RS04545	COG4166	transmembrane transport
HLB24_RS04550	COG0747	negative chemotaxis
HLB24_RS04555	COG0444	Belongs to the ABC transporter superfamily
HLB24_RS04560	COG4608	Belongs to the ABC transporter superfamily
HLB24_RS04565	COG0601	transmembrane transport
HLB24_RS04570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLB24_RS04600	COG1164	Oligoendopeptidase f
HLB24_RS04610	COG2346	COG2346, Truncated hemoglobins
HLB24_RS04625	COG2357	RelA SpoT domain protein
HLB24_RS04635	COG0564	pseudouridine synthase activity
HLB24_RS04640	COG2239	Acts as a magnesium transporter
HLB24_RS04645	COG0569	domain protein
HLB24_RS04645	COG0475	glutathione-regulated potassium exporter activity
HLB24_RS04655	COG0628	permease
HLB24_RS04660	COG1115	amino acid carrier protein
HLB24_RS04710	COG0861	Integral membrane protein TerC family
HLB24_RS04720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HLB24_RS04725	COG0737	Belongs to the 5'-nucleotidase family
HLB24_RS04740	COG4903	ComK protein
HLB24_RS04755	COG4873	Protein conserved in bacteria
HLB24_RS04815	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HLB24_RS04825	COG2314	TM2 domain
HLB24_RS04830	COG0456	acetyltransferase
HLB24_RS04835	COG1575	Belongs to the MenA family. Type 1 subfamily
HLB24_RS04840	COG1169	isochorismate synthase
HLB24_RS04875	COG0436	Aminotransferase
HLB24_RS04880	COG3594	Acyltransferase
HLB24_RS04910	COG1316	TRANSCRIPTIONal
HLB24_RS04955	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLB24_RS04970	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLB24_RS05010	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLB24_RS05015	COG4172	Belongs to the ABC transporter superfamily
HLB24_RS05020	COG4721	ABC-type cobalt transport system, permease component
HLB24_RS05035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HLB24_RS05055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HLB24_RS05060	COG1271	oxidase subunit
HLB24_RS05065	COG1294	oxidase, subunit
HLB24_RS05070	COG0569	domain protein
HLB24_RS05135	COG1176	ABC-type spermidine putrescine transport system, permease component I
HLB24_RS05140	COG1177	transmembrane transport
HLB24_RS05145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HLB24_RS05170	COG0483	inositol monophosphate 1-phosphatase activity
HLB24_RS05190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HLB24_RS05200	COG0772	Belongs to the SEDS family
HLB24_RS05230	COG3679	Belongs to the UPF0342 family
HLB24_RS05250	COG0742	ribosomal rna small subunit methyltransferase
HLB24_RS05305	COG4509	Sortase family
HLB24_RS05320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLB24_RS05350	COG1796	DNA polymerase
HLB24_RS05350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HLB24_RS05375	COG2009	succinate dehydrogenase
HLB24_RS05380	COG1053	succinate dehydrogenase
HLB24_RS05385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HLB24_RS05490	COG1288	antiporter activity
HLB24_RS05525	COG1011	Hydrolase
HLB24_RS05550	COG4839	cell division protein FtsL
HLB24_RS05570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HLB24_RS05575	COG0849	cell division
HLB24_RS05590	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLB24_RS05600	COG0762	integral membrane protein
HLB24_RS05605	COG2302	S4 RNA-binding domain
HLB24_RS05610	COG3599	regulation of cell shape
HLB24_RS05620	COG2514	catechol 2,3-dioxygenase activity
HLB24_RS05635	COG0564	pseudouridine synthase activity
HLB24_RS05645	COG2233	PERMEase
HLB24_RS05690	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HLB24_RS05705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLB24_RS05710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLB24_RS05720	COG2314	TM2 domain
HLB24_RS05735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLB24_RS05735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLB24_RS05745	COG0631	protein serine/threonine phosphatase activity
HLB24_RS05760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HLB24_RS05775	COG1302	Protein conserved in bacteria
HLB24_RS05820	COG1196	nuclear chromosome segregation
HLB24_RS05825	COG0552	protein localization to endoplasmic reticulum
HLB24_RS05835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLB24_RS05890	COG2348	transferase activity, transferring amino-acyl groups
HLB24_RS05895	COG0758	DNA mediated transformation
HLB24_RS05990	COG0195	Participates in both transcription termination and antitermination
HLB24_RS05995	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HLB24_RS06020	COG0196	riboflavin kinase activity
HLB24_RS06045	COG2188	Transcriptional regulator
HLB24_RS06050	COG0612	Peptidase, M16
HLB24_RS06055	COG0612	Peptidase, M16
HLB24_RS06060	COG0300	oxidoreductase activity
HLB24_RS06080	COG1058	Belongs to the CinA family
HLB24_RS06080	COG1546	Belongs to the CinA family
HLB24_RS06100	COG1692	metallophosphoesterase
HLB24_RS06105	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HLB24_RS06105	COG0674	pyruvate-flavodoxin oxidoreductase activity
HLB24_RS06110	COG1013	pyruvate-flavodoxin oxidoreductase activity
HLB24_RS06145	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HLB24_RS06150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HLB24_RS06175	COG1923	regulation of RNA biosynthetic process
HLB24_RS06190	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HLB24_RS06195	COG0789	Transcriptional regulator
HLB24_RS06320	COG1525	nuclease
HLB24_RS06335	COG0527	aspartate kinase activity
HLB24_RS06340	COG0460	homoserine dehydrogenase
HLB24_RS06345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HLB24_RS06370	COG0833	amino acid
HLB24_RS06395	COG2340	Cysteine-rich secretory protein family
HLB24_RS06430	COG4846	Membrane protein involved in cytochrome C biogenesis
HLB24_RS06455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HLB24_RS06465	COG0824	Thioesterase
HLB24_RS06485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLB24_RS06490	COG1115	amino acid carrier protein
HLB24_RS06505	COG0628	permease
HLB24_RS06530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLB24_RS06540	COG1363	Peptidase, m42
HLB24_RS06545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLB24_RS06550	COG0512	Glutamine amidotransferase of anthranilate synthase
HLB24_RS06590	COG0561	phosphatase activity
HLB24_RS06635	COG0704	Plays a role in the regulation of phosphate uptake
HLB24_RS06645	COG0581	inorganic phosphate transmembrane transporter activity
HLB24_RS06650	COG0573	inorganic phosphate transmembrane transporter activity
HLB24_RS06665	COG0488	(ABC) transporter
HLB24_RS06670	COG0527	aspartate kinase activity
HLB24_RS06675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLB24_RS06710	COG2808	Putative FMN-binding domain
HLB24_RS06750	COG4548	von Willebrand factor, type A
HLB24_RS06755	COG0714	Associated with various cellular activities
HLB24_RS06795	COG0671	phosphoesterase, PA-phosphatase related
HLB24_RS06870	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HLB24_RS06890	COG0531	amino acid
HLB24_RS06905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLB24_RS06910	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HLB24_RS06925	COG0116	Belongs to the methyltransferase superfamily
HLB24_RS06960	COG4499	WXG100 protein secretion system (Wss), protein YukC
HLB24_RS06960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HLB24_RS06970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLB24_RS06975	COG3935	DnaD domain protein
HLB24_RS07000	COG0438	transferase activity, transferring glycosyl groups
HLB24_RS07005	COG1694	Mazg nucleotide pyrophosphohydrolase
HLB24_RS07010	COG2738	Putative neutral zinc metallopeptidase
HLB24_RS07015	COG4347	Protein of unknown function (DUF1405)
HLB24_RS07055	COG0142	geranyltranstransferase activity
HLB24_RS07110	COG0492	ferredoxin-NADP+ reductase activity
HLB24_RS07125	COG0514	ATP-dependent DNA helicase (RecQ)
HLB24_RS07135	COG1141	Ferredoxin
HLB24_RS07165	COG5002	protein histidine kinase activity
HLB24_RS07170	COG0745	RESPONSE REGULATOR receiver
HLB24_RS07175	COG1187	pseudouridine synthase activity
HLB24_RS07200	COG0735	belongs to the Fur family
HLB24_RS07205	COG0494	nUDIX hydrolase
HLB24_RS07210	COG0667	Aldo Keto reductase
HLB24_RS07220	COG4221	oxidoreductase activity
HLB24_RS07235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLB24_RS07245	COG0366	Alpha amylase catalytic
HLB24_RS07250	COG1609	Transcriptional regulator
HLB24_RS07270	COG2195	Cleaves the N-terminal amino acid of tripeptides
HLB24_RS07280	COG4129	membrane
HLB24_RS07290	COG0508	dehydrogenase complex catalyzes the overall conversion of
HLB24_RS07295	COG0022	dehydrogenase e1 component
HLB24_RS07300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HLB24_RS07305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HLB24_RS07310	COG0497	DNA recombination
HLB24_RS07340	COG1302	Protein conserved in bacteria
HLB24_RS07345	COG0439	Biotin carboxylase
HLB24_RS07350	COG0511	ligase activity, forming carbon-carbon bonds
HLB24_RS07360	COG0006	proline dipeptidase activity
HLB24_RS07375	COG0095	Lipoate-protein ligase
HLB24_RS07380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLB24_RS07425	COG4537	Required for transformation and DNA binding
HLB24_RS07430	COG1459	type II secretion system
HLB24_RS07435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLB24_RS07440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HLB24_RS07445	COG0011	TIGRFAM Protein of
HLB24_RS07450	COG1940	carbohydrate kinase activity
HLB24_RS07455	COG4483	Protein conserved in bacteria
HLB24_RS07465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLB24_RS07490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HLB24_RS07495	COG1121	(ABC) transporter
HLB24_RS07505	COG0513	Belongs to the DEAD box helicase family
HLB24_RS07515	COG2384	SAM-dependent methyltransferase
HLB24_RS07535	COG0517	IMP dehydrogenase activity
HLB24_RS07555	COG0295	cytidine deaminase activity
HLB24_RS07560	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HLB24_RS07570	COG1702	phosphate starvation-inducible protein PhoH
HLB24_RS07585	COG1030	water channel activity
HLB24_RS07595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HLB24_RS07600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HLB24_RS07630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HLB24_RS07645	COG1466	dna polymerase III delta subunit
HLB24_RS07650	COG0658	competence protein
HLB24_RS07650	COG2333	competence protein COMEC
HLB24_RS07655	COG2131	deaminase
HLB24_RS07665	COG2226	methyltransferase
HLB24_RS07670	COG0799	negative regulation of ribosome biogenesis
HLB24_RS07675	COG1713	HD superfamily hydrolase involved in NAD metabolism
HLB24_RS07685	COG1534	Rna-binding protein
HLB24_RS07695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLB24_RS07700	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HLB24_RS07725	COG3177	Filamentation induced by cAMP protein fic
HLB24_RS07730	COG1914	H( )-stimulated, divalent metal cation uptake system
HLB24_RS07745	COG0511	ligase activity, forming carbon-carbon bonds
HLB24_RS07750	COG1984	allophanate hydrolase subunit 2
HLB24_RS07755	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HLB24_RS07805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HLB24_RS07820	COG1104	cysteine desulfurase activity
HLB24_RS07825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLB24_RS07835	COG3237	CsbD-like
HLB24_RS07840	COG1959	2 iron, 2 sulfur cluster binding
HLB24_RS07845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HLB24_RS07850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HLB24_RS07895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HLB24_RS07895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HLB24_RS07900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HLB24_RS07900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HLB24_RS07905	COG1862	Preprotein translocase
HLB24_RS07945	COG2868	ribosomal protein
HLB24_RS07990	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HLB24_RS07995	COG0285	dihydrofolate synthase activity
HLB24_RS08005	COG2818	Glycosylase
HLB24_RS08040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HLB24_RS08075	COG4112	unkown
HLB24_RS08095	COG0833	amino acid
HLB24_RS08110	COG1484	DNA-dependent DNA replication
HLB24_RS08140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLB24_RS08140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLB24_RS08150	COG5002	protein histidine kinase activity
HLB24_RS08155	COG0745	RESPONSE REGULATOR receiver
HLB24_RS08165	COG0372	Belongs to the citrate synthase family
HLB24_RS08170	COG1113	amino acid transport
HLB24_RS08195	COG0281	malic enzyme
HLB24_RS08205	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HLB24_RS08210	COG4109	DRTGG domain
HLB24_RS08250	COG0827	DNA restriction-modification system
HLB24_RS08260	COG0730	response to heat
HLB24_RS08270	COG1104	cysteine desulfurase activity
HLB24_RS08280	COG1956	GAF domain-containing protein
HLB24_RS08290	COG0584	glycerophosphoryl diester phosphodiesterase
HLB24_RS08295	COG1764	response to oxidative stress
HLB24_RS08300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HLB24_RS08305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HLB24_RS08325	COG1263	PTS System
HLB24_RS08325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HLB24_RS08330	COG0204	Acyl-transferase
HLB24_RS08335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLB24_RS08370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HLB24_RS08375	COG0454	-acetyltransferase
HLB24_RS08395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HLB24_RS08395	COG1605	Chorismate mutase
HLB24_RS08420	COG1674	ftsk spoiiie
HLB24_RS08425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLB24_RS08435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HLB24_RS08440	COG1363	Peptidase, m42
HLB24_RS08450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HLB24_RS08460	COG0510	thiamine kinase activity
HLB24_RS08480	COG1187	pseudouridine synthase activity
HLB24_RS08485	COG2244	polysaccharide biosynthetic process
HLB24_RS08490	COG2081	HI0933 family
HLB24_RS08510	COG2814	Major facilitator Superfamily
HLB24_RS08515	COG1242	4 iron, 4 sulfur cluster binding
HLB24_RS08520	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HLB24_RS08530	COG2267	carboxylic ester hydrolase activity
HLB24_RS08560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLB24_RS08560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLB24_RS08585	COG5632	N-Acetylmuramoyl-L-alanine amidase
HLB24_RS08585	COG4193	domain, Protein
HLB24_RS08585	COG3266	domain, Protein
HLB24_RS08620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HLB24_RS08640	COG0656	L-ascorbic acid biosynthetic process
HLB24_RS08660	COG1506	peptidase
HLB24_RS08665	COG2816	NAD+ diphosphatase activity
HLB24_RS08770	COG1388	LysM domain
HLB24_RS08770	COG5632	N-Acetylmuramoyl-L-alanine amidase
HLB24_RS08815	COG0739	heme binding
HLB24_RS08870	COG0740	serine-type endopeptidase activity
HLB24_RS09090	COG1674	ftsk spoiiie
HLB24_RS09095	COG0433	COG0433 Predicted ATPase
HLB24_RS09115	COG2946	Replication initiation factor
HLB24_RS09230	COG1131	(ABC) transporter
HLB24_RS09235	COG0537	adenosine 5'-monophosphoramidase activity
HLB24_RS09265	COG0420	3'-5' exonuclease activity
HLB24_RS09285	COG2197	response regulator
HLB24_RS09290	COG2203	Gaf domain
HLB24_RS09290	COG4585	Histidine kinase
HLB24_RS09295	COG0564	pseudouridine synthase activity
HLB24_RS09325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HLB24_RS09330	COG1126	abc transporter atp-binding protein
HLB24_RS09335	COG0765	amino acid transport
HLB24_RS09505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HLB24_RS09510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLB24_RS09520	COG4129	membrane
HLB24_RS09535	COG1194	a g-specific adenine glycosylase
HLB24_RS09540	COG1988	membrane-bound metal-dependent
HLB24_RS09550	COG1388	LysM domain
HLB24_RS09550	COG1134	teichoic acid transport
HLB24_RS09580	COG0535	radical SAM domain protein
HLB24_RS09585	COG1607	acyl-coa hydrolase
HLB24_RS09590	COG2309	aminopeptidase activity
HLB24_RS09610	COG1295	ribonuclease BN
HLB24_RS09725	COG4851	CamS sex pheromone cAM373 precursor
HLB24_RS09745	COG4496	protein, YerC YecD
HLB24_RS09780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLB24_RS09790	COG0077	Prephenate dehydratase
HLB24_RS09800	COG0471	metal ion transport
HLB24_RS09810	COG1335	isochorismatase
HLB24_RS09825	COG1012	belongs to the aldehyde dehydrogenase family
HLB24_RS09875	COG1131	(ABC) transporter
HLB24_RS09890	COG1725	Transcriptional regulator
HLB24_RS09935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HLB24_RS10000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLB24_RS10005	COG1621	beta-fructofuranosidase activity
HLB24_RS10010	COG1609	Transcriptional regulator
HLB24_RS10015	COG0004	ammonium transporteR
HLB24_RS10020	COG0425	Belongs to the sulfur carrier protein TusA family
HLB24_RS10025	COG2391	methyltransferase activity
HLB24_RS10035	COG0488	(ABC) transporter
HLB24_RS10050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLB24_RS10060	COG0456	acetyltransferase
HLB24_RS10065	COG1214	PFAM Peptidase M22, glycoprotease
HLB24_RS10070	COG0802	atpase or kinase
HLB24_RS10085	COG0028	Belongs to the TPP enzyme family
HLB24_RS10160	COG2183	response to ionizing radiation
HLB24_RS10165	COG1191	sigma factor activity
HLB24_RS10175	COG1366	Belongs to the anti-sigma-factor antagonist family
HLB24_RS10180	COG2208	phosphoserine phosphatase activity
HLB24_RS10210	COG3428	Bacterial PH domain
HLB24_RS10240	COG2205	protein histidine kinase activity
HLB24_RS10245	COG0745	RESPONSE REGULATOR receiver
HLB24_RS10255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HLB24_RS10265	COG0772	Belongs to the SEDS family
HLB24_RS10280	COG1937	Protein conserved in bacteria
HLB24_RS10290	COG1418	mRNA catabolic process
HLB24_RS10325	COG0629	single-stranded DNA binding
HLB24_RS10410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HLB24_RS10435	COG0009	L-threonylcarbamoyladenylate synthase
HLB24_RS10440	COG2890	protein-(glutamine-N5) methyltransferase activity
HLB24_RS10460	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLB24_RS10500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLB24_RS10545	COG0813	purine-nucleoside phosphorylase activity
HLB24_RS10550	COG0783	Belongs to the Dps family
HLB24_RS10570	COG1482	cell wall glycoprotein biosynthetic process
HLB24_RS10575	COG0702	epimerase
HLB24_RS10580	COG0640	Transcriptional regulator
HLB24_RS10615	COG0561	phosphatase activity
HLB24_RS10620	COG1119	ATPase activity
HLB24_RS10635	COG3711	transcriptional antiterminator
HLB24_RS10665	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLB24_RS10725	COG0489	protein tyrosine kinase activity
HLB24_RS10730	COG2814	Major facilitator Superfamily
HLB24_RS10745	COG1272	protein, Hemolysin III
HLB24_RS10755	COG1988	membrane-bound metal-dependent
HLB24_RS10770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLB24_RS10775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLB24_RS10780	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HLB24_RS10790	COG3457	Alanine racemase
HLB24_RS10795	COG4264	IucA IucC family
HLB24_RS10800	COG2814	Major facilitator Superfamily
HLB24_RS10825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HLB24_RS10835	COG2130	NADP-dependent
HLB24_RS10905	COG0789	Transcriptional regulator
HLB24_RS10915	COG5492	domain, Protein
HLB24_RS10920	COG2378	regulation of single-species biofilm formation
HLB24_RS10925	COG0693	protein deglycase activity
HLB24_RS10935	COG3527	Alpha-acetolactate decarboxylase
HLB24_RS10940	COG0028	Belongs to the TPP enzyme family
HLB24_RS11025	COG0201	protein transport
HLB24_RS11140	COG2252	PERMEase
HLB24_RS11185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HLB24_RS11245	COG1763	Mo-molybdopterin cofactor biosynthetic process
HLB24_RS11265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HLB24_RS11270	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HLB24_RS11275	COG4149	molybdate abc transporter
HLB24_RS11280	COG0725	ABC transporter, periplasmic molybdate-binding protein
HLB24_RS11295	COG1268	BioY protein
HLB24_RS11310	COG1960	acyl-CoA dehydrogenase activity
HLB24_RS11315	COG4413	Urea transporter
HLB24_RS11385	COG1757	Na H antiporter
HLB24_RS11400	COG3942	CHAP domain
HLB24_RS11435	COG1316	TRANSCRIPTIONal
HLB24_RS11465	COG1113	amino acid transport
HLB24_RS11485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HLB24_RS11490	COG0385	Bile acid
HLB24_RS11500	COG1263	PTS System
HLB24_RS11500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HLB24_RS11505	COG1737	Transcriptional regulator
HLB24_RS11525	COG1028	Short-chain dehydrogenase reductase Sdr
HLB24_RS11530	COG1473	amidohydrolase
HLB24_RS11545	COG0583	DNA-binding transcription factor activity
HLB24_RS11565	COG2258	MOSC domain
HLB24_RS11585	COG1668	transmembrane transport
HLB24_RS11590	COG4152	abc transporter atp-binding protein
HLB24_RS11595	COG3152	Membrane
HLB24_RS11605	COG0786	glutamate:sodium symporter activity
HLB24_RS11615	COG0598	Magnesium transport protein CorA
HLB24_RS11630	COG0657	acetylesterase activity
HLB24_RS11640	COG2814	Major facilitator Superfamily
HLB24_RS11645	COG1566	PFAM secretion protein HlyD family protein
HLB24_RS11660	COG2814	Major facilitator Superfamily
HLB24_RS11720	COG1131	(ABC) transporter
HLB24_RS11735	COG1620	l-lactate permease
HLB24_RS11755	COG0604	alcohol dehydrogenase
HLB24_RS11780	COG1511	domain protein
HLB24_RS11795	COG1263	PTS System
HLB24_RS11795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HLB24_RS11810	COG3871	stress protein (general stress protein 26)
HLB24_RS11850	COG0789	Transcriptional regulator
HLB24_RS11870	COG2181	nitrate reductase activity
HLB24_RS11880	COG1140	nitrate reductase beta subunit
HLB24_RS11885	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLB24_RS11895	COG2146	nitrite reductase [NAD(P)H] activity
HLB24_RS11900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HLB24_RS11910	COG0454	-acetyltransferase
HLB24_RS11915	COG2116	formate transmembrane transporter activity
HLB24_RS11930	COG0803	Belongs to the bacterial solute-binding protein 9 family
HLB24_RS11930	COG3443	Belongs to the bacterial solute-binding protein 9 family
HLB24_RS11965	COG1126	abc transporter atp-binding protein
HLB24_RS11970	COG0765	amino acid transport
HLB24_RS11975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HLB24_RS11980	COG2814	Major facilitator Superfamily
HLB24_RS11995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLB24_RS12035	COG0156	8-amino-7-oxononanoate synthase activity
HLB24_RS12045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HLB24_RS12050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HLB24_RS12060	COG1132	(ABC) transporter
HLB24_RS12085	COG1929	Belongs to the glycerate kinase type-1 family
HLB24_RS12095	COG2814	Major facilitator Superfamily
HLB24_RS12110	COG1408	metallophosphoesterase
HLB24_RS12115	COG1113	amino acid transport
HLB24_RS12125	COG0531	amino acid
HLB24_RS12140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLB24_RS12150	COG1174	glycine betaine transport
HLB24_RS12160	COG1174	glycine betaine transport
HLB24_RS12180	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
HLB24_RS12185	COG0531	amino acid
HLB24_RS12190	COG2272	Belongs to the type-B carboxylesterase lipase family
HLB24_RS12195	COG2814	Major facilitator Superfamily
HLB24_RS12200	COG0390	transport system, permease component
HLB24_RS12205	COG4619	ABC transporter
HLB24_RS12210	COG1363	Peptidase, m42
HLB24_RS12215	COG4808	Protein conserved in bacteria
HLB24_RS12220	COG0069	glutamate synthase activity
HLB24_RS12235	COG1124	(ABC) transporter
HLB24_RS12245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLB24_RS12250	COG0601	transmembrane transport
HLB24_RS12255	COG0747	negative chemotaxis
HLB24_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
HLB24_RS12285	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HLB24_RS12290	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLB24_RS12390	COG0494	nUDIX hydrolase
HLB24_RS12430	COG1846	Transcriptional regulator
HLB24_RS12460	COG1070	Carbohydrate kinase
HLB24_RS12465	COG1802	Transcriptional regulator
HLB24_RS12470	COG0789	Transcriptional regulator
HLB24_RS12475	COG2357	RelA SpoT domain protein
HLB24_RS12480	COG4876	unkown
HLB24_RS12490	COG2271	Major facilitator Superfamily
HLB24_RS12495	COG0586	Pfam SNARE associated Golgi protein
HLB24_RS12505	COG1131	(ABC) transporter
HLB24_RS12515	COG1073	alpha beta
HLB24_RS12525	COG1073	alpha beta
HLB24_RS12550	COG3949	Membrane
HLB24_RS12555	COG0400	carboxylic ester hydrolase activity
HLB24_RS12560	COG0346	lactoylglutathione lyase activity
HLB24_RS12565	COG1846	Transcriptional regulator
HLB24_RS12580	COG2514	catechol 2,3-dioxygenase activity
HLB24_RS12600	COG1131	(ABC) transporter
HLB24_RS12610	COG3764	Sortase (surface protein transpeptidase)
HLB24_RS12630	COG1760	l-serine dehydratase
HLB24_RS12635	COG1760	l-serine dehydratase
HLB24_RS12650	COG0697	spore germination
HLB24_RS12655	COG0657	acetylesterase activity
HLB24_RS12675	COG0028	Belongs to the TPP enzyme family
HLB24_RS12690	COG0583	DNA-binding transcription factor activity
HLB24_RS12700	COG3942	CHAP domain
HLB24_RS12710	COG3425	synthase
HLB24_RS12720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLB24_RS12745	COG2409	Drug exporters of the RND superfamily
HLB24_RS12790	COG0436	Aminotransferase
HLB24_RS12830	COG0456	acetyltransferase
HLB24_RS12895	COG0596	Alpha beta hydrolase
HLB24_RS12930	COG3001	Fructosamine kinase
HLB24_RS12935	COG0167	dihydroorotate dehydrogenase activity
HLB24_RS13020	COG2226	methyltransferase
HLB24_RS13055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HLB24_RS13105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLB24_RS13110	COG3527	Alpha-acetolactate decarboxylase
HLB24_RS13120	COG0531	amino acid
HLB24_RS13150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HLB24_RS13170	COG1012	belongs to the aldehyde dehydrogenase family
HLB24_RS13180	COG1510	regulation of RNA biosynthetic process
HLB24_RS13185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HLB24_RS13210	COG2851	Citrate transporter
HLB24_RS13220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HLB24_RS13230	COG0386	Belongs to the glutathione peroxidase family
HLB24_RS13250	COG1136	(ABC) transporter
HLB24_RS13255	COG2205	protein histidine kinase activity
HLB24_RS13260	COG0745	RESPONSE REGULATOR receiver
HLB24_RS13270	COG1785	Belongs to the alkaline phosphatase family
HLB24_RS13280	COG1846	Transcriptional regulator
HLB24_RS13325	COG1438	arginine binding
HLB24_RS13345	COG3711	transcriptional antiterminator
HLB24_RS13345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HLB24_RS13350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HLB24_RS13350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HLB24_RS13350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HLB24_RS13355	COG1482	cell wall glycoprotein biosynthetic process
HLB24_RS13365	COG1705	Flagellar rod assembly protein muramidase FlgJ
HLB24_RS13365	COG3942	CHAP domain
HLB24_RS13370	COG3433	isochorismatase activity
HLB24_RS13370	COG1535	isochorismatase
HLB24_RS13385	COG0438	transferase activity, transferring glycosyl groups
HLB24_RS13400	COG1073	alpha beta
HLB24_RS13420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HLB24_RS13450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HLB24_RS13535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLB24_RS13620	COG0471	metal ion transport
HLB24_RS13625	COG2962	Rard protein
HLB24_RS13635	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HLB24_RS13655	COG1136	(ABC) transporter
HLB24_RS13660	COG0577	efflux transmembrane transporter activity
HLB24_RS13695	COG1278	Cold shock
HLB24_RS13715	COG1475	DNA binding
HLB24_RS13770	COG1846	Transcriptional regulator
HLB24_RS13790	COG3682	Transcriptional regulator
HLB24_RS13810	COG0583	DNA-binding transcription factor activity
HLB24_RS13860	COG0589	response to stress