locus-tag	class	description
ER16_RS00015	COG2501	S4 domain
ER16_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ER16_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ER16_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ER16_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
ER16_RS00110	COG4863	YycH protein
ER16_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ER16_RS00125	COG0737	Belongs to the 5'-nucleotidase family
ER16_RS00155	COG0584	glycerophosphoryl diester phosphodiesterase
ER16_RS00160	COG2030	dehydratase
ER16_RS00250	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ER16_RS00260	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ER16_RS00280	COG2814	Major facilitator Superfamily
ER16_RS00310	COG0655	NAD(P)H dehydrogenase (quinone) activity
ER16_RS00325	COG0583	DNA-binding transcription factor activity
ER16_RS00360	COG0823	Involved in the tonB-independent uptake of proteins
ER16_RS00380	COG1473	amidohydrolase
ER16_RS00390	COG1283	sodium-dependent phosphate transmembrane transporter activity
ER16_RS00395	COG4716	Myosin-crossreactive antigen
ER16_RS00405	COG1620	l-lactate permease
ER16_RS00420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ER16_RS00425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ER16_RS00430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ER16_RS00440	COG2423	ornithine cyclodeaminase activity
ER16_RS00445	COG4264	IucA IucC family
ER16_RS00450	COG2814	Major facilitator Superfamily
ER16_RS00455	COG4264	IucA IucC family
ER16_RS00460	COG4264	IucA IucC family
ER16_RS00470	COG0019	diaminopimelate decarboxylase activity
ER16_RS00475	COG1475	DNA binding
ER16_RS00505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ER16_RS00510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ER16_RS00515	COG0438	transferase activity, transferring glycosyl groups
ER16_RS00545	COG0813	purine-nucleoside phosphorylase activity
ER16_RS00550	COG2814	Major facilitator Superfamily
ER16_RS00570	COG3639	organic phosphonate transmembrane transporter activity
ER16_RS00590	COG0737	Belongs to the 5'-nucleotidase family
ER16_RS00605	COG1012	belongs to the aldehyde dehydrogenase family
ER16_RS00605	COG1454	alcohol dehydrogenase
ER16_RS00635	COG1086	Polysaccharide biosynthesis protein
ER16_RS00645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ER16_RS00675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ER16_RS00685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ER16_RS00690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ER16_RS00700	COG2832	Protein of unknown function (DUF454)
ER16_RS00735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ER16_RS00745	COG5609	conserved protein (DUF2294)
ER16_RS00795	COG1114	Component of the transport system for branched-chain amino acids
ER16_RS00800	COG1335	isochorismatase
ER16_RS00805	COG3961	Belongs to the TPP enzyme family
ER16_RS00835	COG1737	Transcriptional regulator
ER16_RS00870	COG0601	transmembrane transport
ER16_RS00875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ER16_RS00885	COG0405	Gamma-glutamyltransferase
ER16_RS00905	COG3842	ATPase activity
ER16_RS00915	COG1175	transmembrane transport
ER16_RS00920	COG3833	ABC-type maltose transport systems, permease component
ER16_RS00925	COG0673	inositol 2-dehydrogenase activity
ER16_RS00930	COG0673	inositol 2-dehydrogenase activity
ER16_RS00940	COG1755	Isoprenylcysteine carboxyl methyltransferase
ER16_RS01005	COG0183	Belongs to the thiolase family
ER16_RS01015	COG1960	acyl-CoA dehydrogenase activity
ER16_RS01020	COG0318	PFAM AMP-dependent synthetase and ligase
ER16_RS01040	COG0747	negative chemotaxis
ER16_RS01045	COG3189	MarR family transcriptional regulator
ER16_RS01075	COG2190	(PTS) system
ER16_RS01075	COG1263	PTS System
ER16_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ER16_RS01080	COG1957	nucleoside hydrolase
ER16_RS01100	COG3414	Phosphotransferase system galactitol-specific IIB component
ER16_RS01105	COG3775	system Galactitol-specific IIC component
ER16_RS01110	COG1063	alcohol dehydrogenase
ER16_RS01120	COG1063	alcohol dehydrogenase
ER16_RS01130	COG1063	alcohol dehydrogenase
ER16_RS01135	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ER16_RS01140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ER16_RS01150	COG1063	alcohol dehydrogenase
ER16_RS01155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ER16_RS01195	COG2188	Transcriptional regulator
ER16_RS01200	COG1263	PTS System
ER16_RS01200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ER16_RS01200	COG2190	(PTS) system
ER16_RS01205	COG2723	6-phospho-beta-galactosidase activity
ER16_RS01210	COG2226	methyltransferase
ER16_RS01265	COG1131	(ABC) transporter
ER16_RS01285	COG1388	LysM domain
ER16_RS01285	COG3942	CHAP domain
ER16_RS01395	COG1114	Component of the transport system for branched-chain amino acids
ER16_RS01400	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ER16_RS01410	COG0577	efflux transmembrane transporter activity
ER16_RS01435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ER16_RS01440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ER16_RS01465	COG3314	Sporulation integral membrane protein YlbJ
ER16_RS01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ER16_RS01520	COG3037	sugar-specific permease SgaT UlaA
ER16_RS01530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ER16_RS01535	COG3711	transcriptional antiterminator
ER16_RS01555	COG2271	Major facilitator Superfamily
ER16_RS01560	COG0346	lactoylglutathione lyase activity
ER16_RS01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ER16_RS01570	COG0431	NADPH-dependent FMN reductase
ER16_RS01585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ER16_RS01590	COG2822	iron ion transport
ER16_RS01605	COG0672	)-iron permease
ER16_RS01610	COG0805	protein transport
ER16_RS01615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ER16_RS01625	COG1476	TRANSCRIPTIONal
ER16_RS01635	COG1131	(ABC) transporter
ER16_RS01670	COG0646	methionine synthase
ER16_RS01670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ER16_RS01675	COG0626	cystathionine gamma-synthase activity
ER16_RS01680	COG0626	cystathionine gamma-synthase activity
ER16_RS01685	COG1475	DNA binding
ER16_RS01690	COG0668	transmembrane transport
ER16_RS01695	COG4481	Protein conserved in bacteria
ER16_RS01700	COG0012	GTP binding
ER16_RS01800	COG1823	symporter activity
ER16_RS01830	COG2233	PERMEase
ER16_RS01845	COG0582	viral genome integration into host DNA
ER16_RS01900	COG2856	Zn peptidase
ER16_RS01950	COG3759	membrane
ER16_RS02070	COG0523	cobalamin synthesis protein
ER16_RS02080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ER16_RS02090	COG5609	conserved protein (DUF2294)
ER16_RS02105	COG1647	Serine aminopeptidase, S33
ER16_RS02115	COG0733	neurotransmitter:sodium symporter activity
ER16_RS02120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ER16_RS02125	COG0626	cystathionine gamma-synthase activity
ER16_RS02135	COG2011	ABC-type metal ion transport system permease component
ER16_RS02140	COG1464	Belongs to the NlpA lipoprotein family
ER16_RS02155	COG0494	nUDIX hydrolase
ER16_RS02175	COG0583	DNA-binding transcription factor activity
ER16_RS02180	COG0070	glutamate synthase
ER16_RS02180	COG0067	glutamate synthase
ER16_RS02180	COG0069	glutamate synthase activity
ER16_RS02185	COG0493	'glutamate synthase
ER16_RS02195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ER16_RS02195	COG1263	PTS System
ER16_RS02200	COG0366	Alpha amylase catalytic
ER16_RS02205	COG2188	Transcriptional regulator
ER16_RS02220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ER16_RS02255	COG1982	Orn Lys Arg decarboxylase major
ER16_RS02265	COG3870	Protein conserved in bacteria
ER16_RS02275	COG0470	DNA polymerase III
ER16_RS02280	COG1774	PSP1 C-terminal conserved region
ER16_RS02290	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ER16_RS02300	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ER16_RS02315	COG0084	hydrolase, TatD family'
ER16_RS02320	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ER16_RS02330	COG4466	Protein conserved in bacteria
ER16_RS02340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ER16_RS02345	COG0251	oxidation-reduction process
ER16_RS02390	COG2244	polysaccharide biosynthetic process
ER16_RS02395	COG3956	TIGRFAM MazG family protein
ER16_RS02400	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ER16_RS02410	COG1098	S1 RNA binding domain
ER16_RS02425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ER16_RS02450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ER16_RS02545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ER16_RS02560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ER16_RS02570	COG3880	PFAM UvrB UvrC protein
ER16_RS02590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ER16_RS02595	COG4956	integral membrane protein (PIN domain superfamily)
ER16_RS02615	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ER16_RS02665	COG2813	Specifically methylates the guanine in position
ER16_RS02705	COG1473	amidohydrolase
ER16_RS02735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ER16_RS02740	COG1428	Deoxynucleoside kinase
ER16_RS02745	COG1428	Deoxynucleoside kinase
ER16_RS02755	COG0561	phosphatase activity
ER16_RS02795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ER16_RS02900	COG0095	Lipoate-protein ligase
ER16_RS02905	COG0083	homoserine kinase activity
ER16_RS02925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ER16_RS02960	COG0667	Aldo Keto reductase
ER16_RS02965	COG0655	NAD(P)H dehydrogenase (quinone) activity
ER16_RS02975	COG1078	dGTPase activity
ER16_RS03010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ER16_RS03015	COG4139	cobalamin transport
ER16_RS03115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ER16_RS03120	COG1121	(ABC) transporter
ER16_RS03125	COG1321	iron dependent repressor
ER16_RS03135	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ER16_RS03145	COG1682	transport, permease protein
ER16_RS03150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ER16_RS03160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ER16_RS03165	COG1686	Belongs to the peptidase S11 family
ER16_RS03170	COG1132	(ABC) transporter
ER16_RS03175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ER16_RS03185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ER16_RS03190	COG1120	ATPase activity
ER16_RS03195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ER16_RS03200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ER16_RS03205	COG2376	Dihydroxyacetone kinase
ER16_RS03225	COG3949	Membrane
ER16_RS03250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ER16_RS03265	COG1136	(ABC) transporter
ER16_RS03270	COG0577	efflux transmembrane transporter activity
ER16_RS03275	COG1392	Phosphate transport regulator
ER16_RS03280	COG0306	phosphate transporter
ER16_RS03285	COG1388	LysM domain
ER16_RS03285	COG3942	CHAP domain
ER16_RS03295	COG1917	Cupin 2, conserved barrel domain protein
ER16_RS03295	COG4977	sequence-specific DNA binding
ER16_RS03325	COG0583	DNA-binding transcription factor activity
ER16_RS03340	COG2814	Major facilitator Superfamily
ER16_RS03345	COG2839	Protein conserved in bacteria
ER16_RS03375	COG1611	Belongs to the LOG family
ER16_RS03395	COG4988	ABC transporter
ER16_RS03400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ER16_RS03410	COG0523	cobalamin synthesis protein
ER16_RS03415	COG4989	oxidoreductase activity
ER16_RS03425	COG0471	metal ion transport
ER16_RS03430	COG0415	Belongs to the DNA photolyase family
ER16_RS03460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ER16_RS03465	COG1349	DNA-binding transcription factor activity
ER16_RS03470	COG1105	Belongs to the carbohydrate kinase PfkB family
ER16_RS03475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ER16_RS03475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ER16_RS03475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ER16_RS03485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ER16_RS03490	COG1253	flavin adenine dinucleotide binding
ER16_RS03495	COG0656	L-ascorbic acid biosynthetic process
ER16_RS03500	COG0463	Glycosyl transferase, family 2
ER16_RS03535	COG0720	synthase
ER16_RS03545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ER16_RS03545	COG0512	Glutamine amidotransferase of anthranilate synthase
ER16_RS03550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ER16_RS03585	COG0488	(ABC) transporter
ER16_RS03590	COG0514	ATP-dependent DNA helicase (RecQ)
ER16_RS03595	COG1125	glycine betaine transport
ER16_RS03595	COG0517	IMP dehydrogenase activity
ER16_RS03600	COG1174	glycine betaine transport
ER16_RS03625	COG3104	oligopeptide transport
ER16_RS03645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ER16_RS03650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ER16_RS03660	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ER16_RS03665	COG4605	iron ion homeostasis
ER16_RS03670	COG4604	ABC transporter, ATP-binding protein
ER16_RS03675	COG4607	ABC-type enterochelin transport system periplasmic component
ER16_RS03730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ER16_RS03735	COG1739	Uncharacterized protein family UPF0029
ER16_RS03745	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ER16_RS03750	COG1040	competence protein
ER16_RS03780	COG3942	CHAP domain
ER16_RS03780	COG1388	LysM domain
ER16_RS03845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ER16_RS03865	COG0281	malic enzyme
ER16_RS03915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ER16_RS03920	COG1647	Serine aminopeptidase, S33
ER16_RS03925	COG0557	exoribonuclease II activity
ER16_RS03995	COG1278	Cold shock
ER16_RS04035	COG0406	alpha-ribazole phosphatase activity
ER16_RS04040	COG1279	arginine transmembrane transporter activity
ER16_RS04065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ER16_RS04070	COG1393	Belongs to the ArsC family
ER16_RS04085	COG3878	Protein conserved in bacteria
ER16_RS04090	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ER16_RS04105	COG2011	ABC-type metal ion transport system permease component
ER16_RS04110	COG1464	Belongs to the NlpA lipoprotein family
ER16_RS04125	COG0396	ATPase activity
ER16_RS04130	COG0719	Fe-S assembly protein
ER16_RS04140	COG0822	iron-sulfur transferase activity
ER16_RS04155	COG1253	flavin adenine dinucleotide binding
ER16_RS04170	COG1801	Protein of unknown function DUF72
ER16_RS04175	COG0730	response to heat
ER16_RS04190	COG4470	Protein conserved in bacteria
ER16_RS04200	COG2445	Protein of unknown function DUF86
ER16_RS04230	COG1696	Membrane protein involved in D-alanine export
ER16_RS04240	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ER16_RS04245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ER16_RS04250	COG4837	Protein of unknown function (DUF1462)
ER16_RS04255	COG1252	NADH dehydrogenase
ER16_RS04265	COG0316	Belongs to the HesB IscA family
ER16_RS04275	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ER16_RS04280	COG2056	Na+-H+ antiporter family
ER16_RS04285	COG2050	protein possibly involved in aromatic compounds catabolism
ER16_RS04340	COG1098	S1 RNA binding domain
ER16_RS04345	COG1902	pentaerythritol trinitrate reductase activity
ER16_RS04360	COG0584	glycerophosphoryl diester phosphodiesterase
ER16_RS04380	COG0398	Pfam SNARE associated Golgi protein
ER16_RS04420	COG0561	phosphatase activity
ER16_RS04450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ER16_RS04465	COG1881	PFAM PEBP family protein
ER16_RS04495	COG0601	transmembrane transport
ER16_RS04500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ER16_RS04505	COG0444	Belongs to the ABC transporter superfamily
ER16_RS04510	COG4608	Belongs to the ABC transporter superfamily
ER16_RS04515	COG4166	transmembrane transport
ER16_RS04520	COG0747	negative chemotaxis
ER16_RS04525	COG0444	Belongs to the ABC transporter superfamily
ER16_RS04530	COG4608	Belongs to the ABC transporter superfamily
ER16_RS04535	COG0601	transmembrane transport
ER16_RS04540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ER16_RS04580	COG1164	Oligoendopeptidase f
ER16_RS04590	COG2346	COG2346, Truncated hemoglobins
ER16_RS04605	COG2357	RelA SpoT domain protein
ER16_RS04615	COG0564	pseudouridine synthase activity
ER16_RS04620	COG2239	Acts as a magnesium transporter
ER16_RS04625	COG0475	glutathione-regulated potassium exporter activity
ER16_RS04625	COG0569	domain protein
ER16_RS04635	COG0628	permease
ER16_RS04640	COG1115	amino acid carrier protein
ER16_RS04680	COG0861	Integral membrane protein TerC family
ER16_RS04690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ER16_RS04695	COG0737	Belongs to the 5'-nucleotidase family
ER16_RS04710	COG4903	ComK protein
ER16_RS04725	COG4873	Protein conserved in bacteria
ER16_RS04790	COG2314	TM2 domain
ER16_RS04800	COG1575	Belongs to the MenA family. Type 1 subfamily
ER16_RS04805	COG1169	isochorismate synthase
ER16_RS04815	COG2267	carboxylic ester hydrolase activity
ER16_RS04845	COG3594	Acyltransferase
ER16_RS04875	COG1316	TRANSCRIPTIONal
ER16_RS04920	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ER16_RS04935	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ER16_RS04975	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ER16_RS04980	COG4172	Belongs to the ABC transporter superfamily
ER16_RS04985	COG4721	ABC-type cobalt transport system, permease component
ER16_RS05000	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ER16_RS05020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ER16_RS05025	COG1271	oxidase subunit
ER16_RS05030	COG1294	oxidase, subunit
ER16_RS05035	COG0569	domain protein
ER16_RS05105	COG1176	ABC-type spermidine putrescine transport system, permease component I
ER16_RS05110	COG1177	transmembrane transport
ER16_RS05115	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ER16_RS05140	COG0483	inositol monophosphate 1-phosphatase activity
ER16_RS05150	COG1217	gtp-binding protein TYPA
ER16_RS05160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ER16_RS05170	COG0772	Belongs to the SEDS family
ER16_RS05205	COG3679	Belongs to the UPF0342 family
ER16_RS05225	COG0742	ribosomal rna small subunit methyltransferase
ER16_RS05285	COG4509	Sortase family
ER16_RS05300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ER16_RS05330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ER16_RS05330	COG1796	DNA polymerase
ER16_RS05355	COG2009	succinate dehydrogenase
ER16_RS05360	COG1053	succinate dehydrogenase
ER16_RS05365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ER16_RS05485	COG1288	antiporter activity
ER16_RS05520	COG1011	Hydrolase
ER16_RS05545	COG4839	cell division protein FtsL
ER16_RS05550	COG0768	penicillin binding
ER16_RS05565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ER16_RS05570	COG0849	cell division
ER16_RS05585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ER16_RS05595	COG0762	integral membrane protein
ER16_RS05600	COG2302	S4 RNA-binding domain
ER16_RS05605	COG3599	regulation of cell shape
ER16_RS05615	COG2514	catechol 2,3-dioxygenase activity
ER16_RS05630	COG0564	pseudouridine synthase activity
ER16_RS05640	COG2233	PERMEase
ER16_RS05685	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ER16_RS05700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ER16_RS05705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ER16_RS05730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ER16_RS05730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ER16_RS05740	COG0631	protein serine/threonine phosphatase activity
ER16_RS05755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ER16_RS05770	COG1302	Protein conserved in bacteria
ER16_RS05820	COG1196	nuclear chromosome segregation
ER16_RS05825	COG0552	protein localization to endoplasmic reticulum
ER16_RS05835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ER16_RS05900	COG0758	DNA mediated transformation
ER16_RS05995	COG0195	Participates in both transcription termination and antitermination
ER16_RS06000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ER16_RS06025	COG0196	riboflavin kinase activity
ER16_RS06050	COG2188	Transcriptional regulator
ER16_RS06055	COG0612	Peptidase, M16
ER16_RS06060	COG0612	Peptidase, M16
ER16_RS06065	COG0300	oxidoreductase activity
ER16_RS06085	COG1546	Belongs to the CinA family
ER16_RS06085	COG1058	Belongs to the CinA family
ER16_RS06115	COG1692	metallophosphoesterase
ER16_RS06120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ER16_RS06120	COG0674	pyruvate-flavodoxin oxidoreductase activity
ER16_RS06125	COG1013	pyruvate-flavodoxin oxidoreductase activity
ER16_RS06160	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ER16_RS06165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ER16_RS06190	COG1923	regulation of RNA biosynthetic process
ER16_RS06200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ER16_RS06205	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ER16_RS06210	COG0789	Transcriptional regulator
ER16_RS06290	COG3344	reverse transcriptase
ER16_RS06355	COG1131	(ABC) transporter
ER16_RS06370	COG2197	response regulator
ER16_RS06380	COG1525	nuclease
ER16_RS06395	COG0527	aspartate kinase activity
ER16_RS06400	COG0460	homoserine dehydrogenase
ER16_RS06405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ER16_RS06430	COG0833	amino acid
ER16_RS06460	COG2340	Cysteine-rich secretory protein family
ER16_RS06495	COG4846	Membrane protein involved in cytochrome C biogenesis
ER16_RS06515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ER16_RS06540	COG0824	Thioesterase
ER16_RS06570	COG1115	amino acid carrier protein
ER16_RS06585	COG0628	permease
ER16_RS06610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ER16_RS06620	COG1363	Peptidase, m42
ER16_RS06625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ER16_RS06630	COG0512	Glutamine amidotransferase of anthranilate synthase
ER16_RS06690	COG2946	Replication initiation factor
ER16_RS06710	COG0433	COG0433 Predicted ATPase
ER16_RS06725	COG1674	ftsk spoiiie
ER16_RS06755	COG2826	transposase and inactivated derivatives, IS30 family
ER16_RS06760	COG0561	phosphatase activity
ER16_RS06805	COG0704	Plays a role in the regulation of phosphate uptake
ER16_RS06815	COG0581	inorganic phosphate transmembrane transporter activity
ER16_RS06820	COG0573	inorganic phosphate transmembrane transporter activity
ER16_RS06835	COG0488	(ABC) transporter
ER16_RS06840	COG0527	aspartate kinase activity
ER16_RS06845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ER16_RS06920	COG4548	von Willebrand factor, type A
ER16_RS06925	COG0714	Associated with various cellular activities
ER16_RS06975	COG0671	phosphoesterase, PA-phosphatase related
ER16_RS07055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ER16_RS07080	COG0531	amino acid
ER16_RS07095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ER16_RS07100	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ER16_RS07120	COG0116	Belongs to the methyltransferase superfamily
ER16_RS07150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ER16_RS07150	COG4499	WXG100 protein secretion system (Wss), protein YukC
ER16_RS07160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ER16_RS07165	COG3935	DnaD domain protein
ER16_RS07190	COG0438	transferase activity, transferring glycosyl groups
ER16_RS07195	COG1694	Mazg nucleotide pyrophosphohydrolase
ER16_RS07200	COG2738	Putative neutral zinc metallopeptidase
ER16_RS07205	COG4347	Protein of unknown function (DUF1405)
ER16_RS07245	COG0142	geranyltranstransferase activity
ER16_RS07310	COG0492	ferredoxin-NADP+ reductase activity
ER16_RS07325	COG0514	ATP-dependent DNA helicase (RecQ)
ER16_RS07335	COG1141	Ferredoxin
ER16_RS07395	COG5632	N-Acetylmuramoyl-L-alanine amidase
ER16_RS07395	COG1388	LysM domain
ER16_RS07455	COG3953	SLT domain
ER16_RS07455	COG5280	Phage tail tape measure protein TP901
ER16_RS07710	COG0582	viral genome integration into host DNA
ER16_RS07740	COG5002	protein histidine kinase activity
ER16_RS07745	COG0745	RESPONSE REGULATOR receiver
ER16_RS07750	COG1187	pseudouridine synthase activity
ER16_RS07775	COG0735	belongs to the Fur family
ER16_RS07780	COG0494	nUDIX hydrolase
ER16_RS07785	COG0667	Aldo Keto reductase
ER16_RS07795	COG4221	oxidoreductase activity
ER16_RS07810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ER16_RS07820	COG0366	Alpha amylase catalytic
ER16_RS07825	COG1609	Transcriptional regulator
ER16_RS07845	COG2195	Cleaves the N-terminal amino acid of tripeptides
ER16_RS07855	COG4129	membrane
ER16_RS07865	COG0508	dehydrogenase complex catalyzes the overall conversion of
ER16_RS07870	COG0022	dehydrogenase e1 component
ER16_RS07875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ER16_RS07880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ER16_RS07885	COG0497	DNA recombination
ER16_RS07915	COG1302	Protein conserved in bacteria
ER16_RS07920	COG0439	Biotin carboxylase
ER16_RS07925	COG0511	ligase activity, forming carbon-carbon bonds
ER16_RS07935	COG0006	proline dipeptidase activity
ER16_RS07950	COG0095	Lipoate-protein ligase
ER16_RS07955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ER16_RS08000	COG4537	Required for transformation and DNA binding
ER16_RS08005	COG1459	type II secretion system
ER16_RS08010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ER16_RS08015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ER16_RS08020	COG0011	TIGRFAM Protein of
ER16_RS08025	COG1940	carbohydrate kinase activity
ER16_RS08030	COG4483	Protein conserved in bacteria
ER16_RS08040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ER16_RS08050	COG0768	penicillin binding
ER16_RS08065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ER16_RS08070	COG1121	(ABC) transporter
ER16_RS08080	COG0513	Belongs to the DEAD box helicase family
ER16_RS08090	COG2384	SAM-dependent methyltransferase
ER16_RS08110	COG0517	IMP dehydrogenase activity
ER16_RS08130	COG0295	cytidine deaminase activity
ER16_RS08145	COG1702	phosphate starvation-inducible protein PhoH
ER16_RS08160	COG1030	water channel activity
ER16_RS08170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ER16_RS08175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ER16_RS08205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ER16_RS08225	COG1466	dna polymerase III delta subunit
ER16_RS08230	COG0658	competence protein
ER16_RS08230	COG2333	competence protein COMEC
ER16_RS08235	COG2131	deaminase
ER16_RS08240	COG2183	response to ionizing radiation
ER16_RS08245	COG2226	methyltransferase
ER16_RS08250	COG0799	negative regulation of ribosome biogenesis
ER16_RS08255	COG1713	HD superfamily hydrolase involved in NAD metabolism
ER16_RS08265	COG1534	Rna-binding protein
ER16_RS08275	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ER16_RS08280	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ER16_RS08305	COG3177	Filamentation induced by cAMP protein fic
ER16_RS08310	COG1914	H( )-stimulated, divalent metal cation uptake system
ER16_RS08320	COG0439	Biotin carboxylase
ER16_RS08325	COG0511	ligase activity, forming carbon-carbon bonds
ER16_RS08330	COG1984	allophanate hydrolase subunit 2
ER16_RS08335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ER16_RS08350	COG0826	peptidase U32
ER16_RS08355	COG0826	peptidase U32
ER16_RS08385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ER16_RS08400	COG1104	cysteine desulfurase activity
ER16_RS08405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ER16_RS08415	COG3237	CsbD-like
ER16_RS08420	COG1959	2 iron, 2 sulfur cluster binding
ER16_RS08425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ER16_RS08430	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ER16_RS08470	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ER16_RS08470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ER16_RS08475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ER16_RS08475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ER16_RS08480	COG1862	Preprotein translocase
ER16_RS08520	COG2868	ribosomal protein
ER16_RS08560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ER16_RS08570	COG0285	dihydrofolate synthase activity
ER16_RS08580	COG2818	Glycosylase
ER16_RS08615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ER16_RS08650	COG4112	unkown
ER16_RS08675	COG0833	amino acid
ER16_RS08690	COG1484	DNA-dependent DNA replication
ER16_RS08720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ER16_RS08720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ER16_RS08730	COG5002	protein histidine kinase activity
ER16_RS08735	COG0745	RESPONSE REGULATOR receiver
ER16_RS08750	COG0372	Belongs to the citrate synthase family
ER16_RS08755	COG1113	amino acid transport
ER16_RS08780	COG0281	malic enzyme
ER16_RS08790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ER16_RS08795	COG4109	DRTGG domain
ER16_RS08835	COG0827	DNA restriction-modification system
ER16_RS08845	COG0730	response to heat
ER16_RS08855	COG1104	cysteine desulfurase activity
ER16_RS08870	COG1956	GAF domain-containing protein
ER16_RS08885	COG0584	glycerophosphoryl diester phosphodiesterase
ER16_RS08890	COG1764	response to oxidative stress
ER16_RS08895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ER16_RS08900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ER16_RS08915	COG1263	PTS System
ER16_RS08915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ER16_RS08920	COG0204	Acyl-transferase
ER16_RS08925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ER16_RS08945	COG5386	Cell surface protein
ER16_RS08960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ER16_RS08965	COG0454	-acetyltransferase
ER16_RS08985	COG1605	Chorismate mutase
ER16_RS08985	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ER16_RS09010	COG1674	ftsk spoiiie
ER16_RS09015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ER16_RS09025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ER16_RS09030	COG1363	Peptidase, m42
ER16_RS09040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ER16_RS09050	COG0510	thiamine kinase activity
ER16_RS09070	COG1187	pseudouridine synthase activity
ER16_RS09075	COG2244	polysaccharide biosynthetic process
ER16_RS09080	COG2081	HI0933 family
ER16_RS09100	COG2814	Major facilitator Superfamily
ER16_RS09105	COG1242	4 iron, 4 sulfur cluster binding
ER16_RS09110	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ER16_RS09125	COG2267	carboxylic ester hydrolase activity
ER16_RS09155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ER16_RS09155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ER16_RS09195	COG5632	N-Acetylmuramoyl-L-alanine amidase
ER16_RS09195	COG4193	domain, Protein
ER16_RS09195	COG3266	domain, Protein
ER16_RS09230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ER16_RS09265	COG0656	L-ascorbic acid biosynthetic process
ER16_RS09285	COG1506	peptidase
ER16_RS09405	COG0758	DNA mediated transformation
ER16_RS09510	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ER16_RS09540	COG1131	(ABC) transporter
ER16_RS09545	COG0537	adenosine 5'-monophosphoramidase activity
ER16_RS09575	COG0420	3'-5' exonuclease activity
ER16_RS09600	COG2197	response regulator
ER16_RS09605	COG2203	Gaf domain
ER16_RS09605	COG4585	Histidine kinase
ER16_RS09610	COG0564	pseudouridine synthase activity
ER16_RS09645	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ER16_RS09650	COG1126	abc transporter atp-binding protein
ER16_RS09655	COG0765	amino acid transport
ER16_RS09825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ER16_RS09830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ER16_RS09840	COG4129	membrane
ER16_RS09865	COG1988	membrane-bound metal-dependent
ER16_RS09880	COG1388	LysM domain
ER16_RS09880	COG1134	teichoic acid transport
ER16_RS09910	COG0535	radical SAM domain protein
ER16_RS09915	COG1607	acyl-coa hydrolase
ER16_RS09920	COG2309	aminopeptidase activity
ER16_RS09940	COG1295	ribonuclease BN
ER16_RS10055	COG4851	CamS sex pheromone cAM373 precursor
ER16_RS10075	COG4496	protein, YerC YecD
ER16_RS10125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ER16_RS10135	COG0077	Prephenate dehydratase
ER16_RS10145	COG0471	metal ion transport
ER16_RS10155	COG1335	isochorismatase
ER16_RS10170	COG1012	belongs to the aldehyde dehydrogenase family
ER16_RS10180	COG3682	Transcriptional regulator
ER16_RS10205	COG4974	Belongs to the 'phage' integrase family
ER16_RS10255	COG1131	(ABC) transporter
ER16_RS10270	COG1725	Transcriptional regulator
ER16_RS10340	COG5632	N-Acetylmuramoyl-L-alanine amidase
ER16_RS10340	COG1388	LysM domain
ER16_RS10380	COG0739	heme binding
ER16_RS10430	COG0740	serine-type endopeptidase activity
ER16_RS10670	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ER16_RS10675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ER16_RS10680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ER16_RS10695	COG3728	DNA packaging
ER16_RS10695	COG5484	DNA packaging
ER16_RS10770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ER16_RS10775	COG1621	beta-fructofuranosidase activity
ER16_RS10780	COG1609	Transcriptional regulator
ER16_RS10785	COG0004	ammonium transporteR
ER16_RS10790	COG0425	Belongs to the sulfur carrier protein TusA family
ER16_RS10795	COG2391	methyltransferase activity
ER16_RS10805	COG0488	(ABC) transporter
ER16_RS10820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ER16_RS10830	COG0456	acetyltransferase
ER16_RS10835	COG1214	PFAM Peptidase M22, glycoprotease
ER16_RS10840	COG0802	atpase or kinase
ER16_RS10855	COG0028	Belongs to the TPP enzyme family
ER16_RS10935	COG2183	response to ionizing radiation
ER16_RS10940	COG1191	sigma factor activity
ER16_RS10950	COG1366	Belongs to the anti-sigma-factor antagonist family
ER16_RS10955	COG2208	phosphoserine phosphatase activity
ER16_RS10990	COG3428	Bacterial PH domain
ER16_RS11020	COG2205	protein histidine kinase activity
ER16_RS11025	COG0745	RESPONSE REGULATOR receiver
ER16_RS11035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ER16_RS11045	COG0772	Belongs to the SEDS family
ER16_RS11060	COG1937	Protein conserved in bacteria
ER16_RS11070	COG1418	mRNA catabolic process
ER16_RS11110	COG0629	single-stranded DNA binding
ER16_RS11190	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ER16_RS11215	COG0009	L-threonylcarbamoyladenylate synthase
ER16_RS11220	COG2890	protein-(glutamine-N5) methyltransferase activity
ER16_RS11240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ER16_RS11280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ER16_RS11330	COG0813	purine-nucleoside phosphorylase activity
ER16_RS11335	COG0783	Belongs to the Dps family
ER16_RS11355	COG1482	cell wall glycoprotein biosynthetic process
ER16_RS11360	COG0702	epimerase
ER16_RS11365	COG0640	Transcriptional regulator
ER16_RS11390	COG0561	phosphatase activity
ER16_RS11395	COG1119	ATPase activity
ER16_RS11410	COG3711	transcriptional antiterminator
ER16_RS11440	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ER16_RS11500	COG0489	protein tyrosine kinase activity
ER16_RS11505	COG2814	Major facilitator Superfamily
ER16_RS11520	COG1272	protein, Hemolysin III
ER16_RS11530	COG1988	membrane-bound metal-dependent
ER16_RS11540	COG3314	Sporulation integral membrane protein YlbJ
ER16_RS11545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ER16_RS11550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ER16_RS11555	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ER16_RS11565	COG3457	Alanine racemase
ER16_RS11570	COG4264	IucA IucC family
ER16_RS11575	COG2814	Major facilitator Superfamily
ER16_RS11600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ER16_RS11610	COG2130	NADP-dependent
ER16_RS11680	COG0656	L-ascorbic acid biosynthetic process
ER16_RS11685	COG0789	Transcriptional regulator
ER16_RS11695	COG5492	domain, Protein
ER16_RS11710	COG0438	transferase activity, transferring glycosyl groups
ER16_RS11725	COG3527	Alpha-acetolactate decarboxylase
ER16_RS11730	COG0028	Belongs to the TPP enzyme family
ER16_RS11810	COG0201	protein transport
ER16_RS11925	COG2252	PERMEase
ER16_RS11970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ER16_RS12035	COG1763	Mo-molybdopterin cofactor biosynthetic process
ER16_RS12055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ER16_RS12060	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ER16_RS12065	COG4149	molybdate abc transporter
ER16_RS12070	COG0725	ABC transporter, periplasmic molybdate-binding protein
ER16_RS12085	COG1268	BioY protein
ER16_RS12100	COG1960	acyl-CoA dehydrogenase activity
ER16_RS12105	COG4413	Urea transporter
ER16_RS12180	COG1757	Na H antiporter
ER16_RS12195	COG3942	CHAP domain
ER16_RS12235	COG1316	TRANSCRIPTIONal
ER16_RS12265	COG1113	amino acid transport
ER16_RS12285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ER16_RS12290	COG0385	Bile acid
ER16_RS12300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ER16_RS12300	COG1263	PTS System
ER16_RS12305	COG1737	Transcriptional regulator
ER16_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
ER16_RS12330	COG1473	amidohydrolase
ER16_RS12345	COG0583	DNA-binding transcription factor activity
ER16_RS12365	COG2258	MOSC domain
ER16_RS12385	COG1668	transmembrane transport
ER16_RS12390	COG4152	abc transporter atp-binding protein
ER16_RS12395	COG3152	Membrane
ER16_RS12405	COG0786	glutamate:sodium symporter activity
ER16_RS12415	COG0598	Magnesium transport protein CorA
ER16_RS12430	COG0657	acetylesterase activity
ER16_RS12440	COG2814	Major facilitator Superfamily
ER16_RS12445	COG1566	PFAM secretion protein HlyD family protein
ER16_RS12455	COG2814	Major facilitator Superfamily
ER16_RS12515	COG1131	(ABC) transporter
ER16_RS12530	COG1620	l-lactate permease
ER16_RS12550	COG0604	alcohol dehydrogenase
ER16_RS12580	COG1511	domain protein
ER16_RS12595	COG1263	PTS System
ER16_RS12595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ER16_RS12610	COG3871	stress protein (general stress protein 26)
ER16_RS12650	COG0789	Transcriptional regulator
ER16_RS12670	COG2181	nitrate reductase activity
ER16_RS12680	COG1140	nitrate reductase beta subunit
ER16_RS12685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ER16_RS12695	COG2146	nitrite reductase [NAD(P)H] activity
ER16_RS12700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ER16_RS12710	COG0454	-acetyltransferase
ER16_RS12715	COG2116	formate transmembrane transporter activity
ER16_RS12730	COG3443	Belongs to the bacterial solute-binding protein 9 family
ER16_RS12730	COG0803	Belongs to the bacterial solute-binding protein 9 family
ER16_RS12765	COG1126	abc transporter atp-binding protein
ER16_RS12770	COG0765	amino acid transport
ER16_RS12775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ER16_RS12780	COG2814	Major facilitator Superfamily
ER16_RS12795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ER16_RS12840	COG0156	8-amino-7-oxononanoate synthase activity
ER16_RS12850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ER16_RS12855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ER16_RS12880	COG1132	(ABC) transporter
ER16_RS12885	COG2375	cellular response to nickel ion
ER16_RS12885	COG1132	(ABC) transporter
ER16_RS12905	COG1929	Belongs to the glycerate kinase type-1 family
ER16_RS12915	COG2814	Major facilitator Superfamily
ER16_RS12935	COG1113	amino acid transport
ER16_RS12950	COG0531	amino acid
ER16_RS12975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ER16_RS12985	COG1174	glycine betaine transport
ER16_RS12995	COG1174	glycine betaine transport
ER16_RS13015	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ER16_RS13020	COG0531	amino acid
ER16_RS13025	COG2272	Belongs to the type-B carboxylesterase lipase family
ER16_RS13030	COG2814	Major facilitator Superfamily
ER16_RS13035	COG0390	transport system, permease component
ER16_RS13040	COG4619	ABC transporter
ER16_RS13045	COG1363	Peptidase, m42
ER16_RS13065	COG4808	Protein conserved in bacteria
ER16_RS13070	COG0069	glutamate synthase activity
ER16_RS13085	COG1124	(ABC) transporter
ER16_RS13095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ER16_RS13105	COG0747	negative chemotaxis
ER16_RS13130	COG1028	Short-chain dehydrogenase reductase Sdr
ER16_RS13135	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ER16_RS13140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ER16_RS13230	COG0494	nUDIX hydrolase
ER16_RS13270	COG1846	Transcriptional regulator
ER16_RS13300	COG1070	Carbohydrate kinase
ER16_RS13305	COG1802	Transcriptional regulator
ER16_RS13310	COG0789	Transcriptional regulator
ER16_RS13315	COG2357	RelA SpoT domain protein
ER16_RS13320	COG4876	unkown
ER16_RS13330	COG2271	Major facilitator Superfamily
ER16_RS13335	COG0586	Pfam SNARE associated Golgi protein
ER16_RS13345	COG2814	Major facilitator Superfamily
ER16_RS13355	COG1131	(ABC) transporter
ER16_RS13375	COG3949	Membrane
ER16_RS13380	COG0400	carboxylic ester hydrolase activity
ER16_RS13385	COG0346	lactoylglutathione lyase activity
ER16_RS13390	COG1846	Transcriptional regulator
ER16_RS13395	COG2388	GCN5-related N-acetyl-transferase
ER16_RS13400	COG2514	catechol 2,3-dioxygenase activity
ER16_RS13420	COG0561	phosphatase activity
ER16_RS13425	COG1131	(ABC) transporter
ER16_RS13435	COG3764	Sortase (surface protein transpeptidase)
ER16_RS13455	COG1760	l-serine dehydratase
ER16_RS13460	COG1760	l-serine dehydratase
ER16_RS13475	COG0697	spore germination
ER16_RS13480	COG0657	acetylesterase activity
ER16_RS13515	COG0028	Belongs to the TPP enzyme family
ER16_RS13530	COG0583	DNA-binding transcription factor activity
ER16_RS13540	COG3942	CHAP domain
ER16_RS13550	COG3425	synthase
ER16_RS13555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ER16_RS13580	COG2409	Drug exporters of the RND superfamily
ER16_RS13625	COG0436	Aminotransferase
ER16_RS13660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ER16_RS13660	COG2755	lipolytic protein G-D-S-L family
ER16_RS13665	COG0456	acetyltransferase
ER16_RS13730	COG0596	Alpha beta hydrolase
ER16_RS13770	COG3001	Fructosamine kinase
ER16_RS13775	COG0167	dihydroorotate dehydrogenase activity
ER16_RS13835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ER16_RS13840	COG3527	Alpha-acetolactate decarboxylase
ER16_RS13860	COG0531	amino acid
ER16_RS13890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ER16_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
ER16_RS13920	COG1510	regulation of RNA biosynthetic process
ER16_RS13925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ER16_RS13950	COG2851	Citrate transporter
ER16_RS13965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ER16_RS13975	COG0386	Belongs to the glutathione peroxidase family
ER16_RS14000	COG1136	(ABC) transporter
ER16_RS14005	COG2205	protein histidine kinase activity
ER16_RS14010	COG0745	RESPONSE REGULATOR receiver
ER16_RS14025	COG1785	Belongs to the alkaline phosphatase family
ER16_RS14030	COG1846	Transcriptional regulator
ER16_RS14075	COG1438	arginine binding
ER16_RS14095	COG3711	transcriptional antiterminator
ER16_RS14095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ER16_RS14100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ER16_RS14100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ER16_RS14100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ER16_RS14105	COG1482	cell wall glycoprotein biosynthetic process
ER16_RS14115	COG1705	Flagellar rod assembly protein muramidase FlgJ
ER16_RS14115	COG3942	CHAP domain
ER16_RS14120	COG3433	isochorismatase activity
ER16_RS14120	COG1535	isochorismatase
ER16_RS14135	COG0438	transferase activity, transferring glycosyl groups
ER16_RS14150	COG1073	alpha beta
ER16_RS14170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ER16_RS14190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ER16_RS14280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ER16_RS14340	COG0471	metal ion transport
ER16_RS14345	COG2962	Rard protein
ER16_RS14355	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ER16_RS14370	COG1136	(ABC) transporter
ER16_RS14375	COG0577	efflux transmembrane transporter activity
ER16_RS14385	COG1278	Cold shock
ER16_RS14410	COG1475	DNA binding