locus-tag	class	description
E1950_RS00045	COG0730	response to heat
E1950_RS00050	COG1937	Protein conserved in bacteria
E1950_RS00055	COG2210	Belongs to the sulfur carrier protein TusA family
E1950_RS00060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1950_RS00115	COG0823	Involved in the tonB-independent uptake of proteins
E1950_RS00150	COG1473	amidohydrolase
E1950_RS00160	COG1283	sodium-dependent phosphate transmembrane transporter activity
E1950_RS00165	COG4716	Myosin-crossreactive antigen
E1950_RS00170	COG0697	spore germination
E1950_RS00185	COG1620	l-lactate permease
E1950_RS00205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1950_RS00210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1950_RS00215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1950_RS00225	COG2423	ornithine cyclodeaminase activity
E1950_RS00230	COG4264	IucA IucC family
E1950_RS00235	COG2814	Major facilitator Superfamily
E1950_RS00240	COG4264	IucA IucC family
E1950_RS00245	COG4264	IucA IucC family
E1950_RS00255	COG0019	diaminopimelate decarboxylase activity
E1950_RS00260	COG1475	DNA binding
E1950_RS00280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E1950_RS00285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E1950_RS00290	COG0438	transferase activity, transferring glycosyl groups
E1950_RS00320	COG0813	purine-nucleoside phosphorylase activity
E1950_RS00325	COG2814	Major facilitator Superfamily
E1950_RS00345	COG3639	organic phosphonate transmembrane transporter activity
E1950_RS00365	COG0737	Belongs to the 5'-nucleotidase family
E1950_RS00380	COG1454	alcohol dehydrogenase
E1950_RS00380	COG1012	belongs to the aldehyde dehydrogenase family
E1950_RS00405	COG1086	Polysaccharide biosynthesis protein
E1950_RS00415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E1950_RS00445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E1950_RS00455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E1950_RS00460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E1950_RS00470	COG2832	Protein of unknown function (DUF454)
E1950_RS00510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E1950_RS00515	COG1960	acyl-CoA dehydrogenase activity
E1950_RS00520	COG5609	conserved protein (DUF2294)
E1950_RS00570	COG1114	Component of the transport system for branched-chain amino acids
E1950_RS00575	COG1335	isochorismatase
E1950_RS00580	COG3961	Belongs to the TPP enzyme family
E1950_RS00610	COG1737	Transcriptional regulator
E1950_RS00635	COG1136	(ABC) transporter
E1950_RS00640	COG1136	(ABC) transporter
E1950_RS00640	COG0577	efflux transmembrane transporter activity
E1950_RS00660	COG1131	(ABC) transporter
E1950_RS00675	COG0601	transmembrane transport
E1950_RS00680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1950_RS00690	COG0405	Gamma-glutamyltransferase
E1950_RS00710	COG3842	ATPase activity
E1950_RS00720	COG1175	transmembrane transport
E1950_RS00725	COG3833	ABC-type maltose transport systems, permease component
E1950_RS00730	COG0673	inositol 2-dehydrogenase activity
E1950_RS00735	COG0673	inositol 2-dehydrogenase activity
E1950_RS00745	COG1755	Isoprenylcysteine carboxyl methyltransferase
E1950_RS00800	COG0183	Belongs to the thiolase family
E1950_RS00810	COG1960	acyl-CoA dehydrogenase activity
E1950_RS00815	COG0318	PFAM AMP-dependent synthetase and ligase
E1950_RS00830	COG0747	negative chemotaxis
E1950_RS00835	COG3189	MarR family transcriptional regulator
E1950_RS00860	COG1263	PTS System
E1950_RS00860	COG2190	(PTS) system
E1950_RS00860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1950_RS00865	COG1957	nucleoside hydrolase
E1950_RS00885	COG3414	Phosphotransferase system galactitol-specific IIB component
E1950_RS00890	COG3775	system Galactitol-specific IIC component
E1950_RS00895	COG1063	alcohol dehydrogenase
E1950_RS00905	COG1063	alcohol dehydrogenase
E1950_RS00915	COG1063	alcohol dehydrogenase
E1950_RS00920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E1950_RS00925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E1950_RS00935	COG1063	alcohol dehydrogenase
E1950_RS00940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E1950_RS00975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1950_RS00980	COG2190	(PTS) system
E1950_RS00980	COG1263	PTS System
E1950_RS00980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1950_RS00985	COG2723	6-phospho-beta-galactosidase activity
E1950_RS00990	COG2226	methyltransferase
E1950_RS01045	COG1131	(ABC) transporter
E1950_RS01065	COG3942	CHAP domain
E1950_RS01065	COG1388	LysM domain
E1950_RS01185	COG1114	Component of the transport system for branched-chain amino acids
E1950_RS01195	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E1950_RS01205	COG0577	efflux transmembrane transporter activity
E1950_RS01235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1950_RS01240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E1950_RS01265	COG3314	Sporulation integral membrane protein YlbJ
E1950_RS01290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E1950_RS01320	COG3037	sugar-specific permease SgaT UlaA
E1950_RS01330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1950_RS01335	COG3711	transcriptional antiterminator
E1950_RS01360	COG2271	Major facilitator Superfamily
E1950_RS01365	COG0346	lactoylglutathione lyase activity
E1950_RS01370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E1950_RS01375	COG0431	NADPH-dependent FMN reductase
E1950_RS01385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1950_RS01390	COG2822	iron ion transport
E1950_RS01400	COG0672	)-iron permease
E1950_RS01405	COG0805	protein transport
E1950_RS01410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E1950_RS01420	COG1476	TRANSCRIPTIONal
E1950_RS01430	COG1131	(ABC) transporter
E1950_RS01460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E1950_RS01460	COG0646	methionine synthase
E1950_RS01465	COG0626	cystathionine gamma-synthase activity
E1950_RS01470	COG0626	cystathionine gamma-synthase activity
E1950_RS01480	COG1475	DNA binding
E1950_RS01485	COG0668	transmembrane transport
E1950_RS01490	COG4481	Protein conserved in bacteria
E1950_RS01495	COG0012	GTP binding
E1950_RS01600	COG1823	symporter activity
E1950_RS01635	COG2233	PERMEase
E1950_RS01670	COG3759	membrane
E1950_RS01830	COG0523	cobalamin synthesis protein
E1950_RS01855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E1950_RS01865	COG5609	conserved protein (DUF2294)
E1950_RS01880	COG1647	Serine aminopeptidase, S33
E1950_RS01885	COG0733	neurotransmitter:sodium symporter activity
E1950_RS01890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E1950_RS01895	COG0626	cystathionine gamma-synthase activity
E1950_RS01905	COG2011	ABC-type metal ion transport system permease component
E1950_RS01910	COG1464	Belongs to the NlpA lipoprotein family
E1950_RS01945	COG0583	DNA-binding transcription factor activity
E1950_RS01950	COG0070	glutamate synthase
E1950_RS01950	COG0069	glutamate synthase activity
E1950_RS01950	COG0067	glutamate synthase
E1950_RS01955	COG0493	'glutamate synthase
E1950_RS01965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1950_RS01965	COG1263	PTS System
E1950_RS01970	COG0366	Alpha amylase catalytic
E1950_RS01975	COG2188	Transcriptional regulator
E1950_RS01995	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E1950_RS02025	COG1982	Orn Lys Arg decarboxylase major
E1950_RS02035	COG3870	Protein conserved in bacteria
E1950_RS02040	COG0470	DNA polymerase III
E1950_RS02045	COG1774	PSP1 C-terminal conserved region
E1950_RS02055	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E1950_RS02065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E1950_RS02075	COG0084	hydrolase, TatD family'
E1950_RS02080	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E1950_RS02090	COG4466	Protein conserved in bacteria
E1950_RS02100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E1950_RS02105	COG0251	oxidation-reduction process
E1950_RS02145	COG2244	polysaccharide biosynthetic process
E1950_RS02150	COG3956	TIGRFAM MazG family protein
E1950_RS02155	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E1950_RS02165	COG1098	S1 RNA binding domain
E1950_RS02180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E1950_RS02205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E1950_RS02270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1950_RS02285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1950_RS02295	COG3880	PFAM UvrB UvrC protein
E1950_RS02310	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E1950_RS02315	COG4956	integral membrane protein (PIN domain superfamily)
E1950_RS02335	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E1950_RS02395	COG2813	Specifically methylates the guanine in position
E1950_RS02435	COG1473	amidohydrolase
E1950_RS02465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E1950_RS02470	COG1428	Deoxynucleoside kinase
E1950_RS02475	COG1428	Deoxynucleoside kinase
E1950_RS02485	COG0561	phosphatase activity
E1950_RS02525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E1950_RS02540	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E1950_RS02640	COG0095	Lipoate-protein ligase
E1950_RS02645	COG0083	homoserine kinase activity
E1950_RS02665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E1950_RS02700	COG0667	Aldo Keto reductase
E1950_RS02710	COG0655	NAD(P)H dehydrogenase (quinone) activity
E1950_RS02720	COG1078	dGTPase activity
E1950_RS02755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1950_RS02760	COG4139	cobalamin transport
E1950_RS02810	COG4974	Belongs to the 'phage' integrase family
E1950_RS02860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E1950_RS02865	COG1121	(ABC) transporter
E1950_RS02870	COG1321	iron dependent repressor
E1950_RS02880	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
E1950_RS02890	COG1682	transport, permease protein
E1950_RS02895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E1950_RS02905	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E1950_RS02910	COG1686	Belongs to the peptidase S11 family
E1950_RS02915	COG1132	(ABC) transporter
E1950_RS02920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1950_RS02930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1950_RS02935	COG1120	ATPase activity
E1950_RS02940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1950_RS02945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1950_RS02950	COG2376	Dihydroxyacetone kinase
E1950_RS02960	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E1950_RS02970	COG3949	Membrane
E1950_RS02990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E1950_RS03005	COG1136	(ABC) transporter
E1950_RS03010	COG0577	efflux transmembrane transporter activity
E1950_RS03015	COG1392	Phosphate transport regulator
E1950_RS03020	COG0306	phosphate transporter
E1950_RS03025	COG3942	CHAP domain
E1950_RS03025	COG1388	LysM domain
E1950_RS03035	COG4977	sequence-specific DNA binding
E1950_RS03035	COG1917	Cupin 2, conserved barrel domain protein
E1950_RS03065	COG0583	DNA-binding transcription factor activity
E1950_RS03070	COG2814	Major facilitator Superfamily
E1950_RS03075	COG2839	Protein conserved in bacteria
E1950_RS03105	COG1611	Belongs to the LOG family
E1950_RS03125	COG4988	ABC transporter
E1950_RS03130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E1950_RS03140	COG0523	cobalamin synthesis protein
E1950_RS03145	COG4989	oxidoreductase activity
E1950_RS03155	COG0471	metal ion transport
E1950_RS03160	COG0415	Belongs to the DNA photolyase family
E1950_RS03190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E1950_RS03195	COG1349	DNA-binding transcription factor activity
E1950_RS03200	COG1105	Belongs to the carbohydrate kinase PfkB family
E1950_RS03205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1950_RS03205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1950_RS03205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1950_RS03210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E1950_RS03215	COG1253	flavin adenine dinucleotide binding
E1950_RS03220	COG0656	L-ascorbic acid biosynthetic process
E1950_RS03225	COG0463	Glycosyl transferase, family 2
E1950_RS03260	COG0720	synthase
E1950_RS03270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E1950_RS03270	COG0512	Glutamine amidotransferase of anthranilate synthase
E1950_RS03275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E1950_RS03305	COG0488	(ABC) transporter
E1950_RS03310	COG0514	ATP-dependent DNA helicase (RecQ)
E1950_RS03315	COG0517	IMP dehydrogenase activity
E1950_RS03315	COG1125	glycine betaine transport
E1950_RS03320	COG1174	glycine betaine transport
E1950_RS03350	COG3104	oligopeptide transport
E1950_RS03380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E1950_RS03385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E1950_RS03395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1950_RS03400	COG4605	iron ion homeostasis
E1950_RS03405	COG4604	ABC transporter, ATP-binding protein
E1950_RS03410	COG4607	ABC-type enterochelin transport system periplasmic component
E1950_RS03465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E1950_RS03470	COG1739	Uncharacterized protein family UPF0029
E1950_RS03480	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E1950_RS03485	COG1040	competence protein
E1950_RS03515	COG1388	LysM domain
E1950_RS03515	COG3942	CHAP domain
E1950_RS03570	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E1950_RS03640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E1950_RS03645	COG1647	Serine aminopeptidase, S33
E1950_RS03650	COG0557	exoribonuclease II activity
E1950_RS03725	COG1278	Cold shock
E1950_RS03765	COG0406	alpha-ribazole phosphatase activity
E1950_RS03770	COG1279	arginine transmembrane transporter activity
E1950_RS03800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1950_RS03805	COG1393	Belongs to the ArsC family
E1950_RS03820	COG3878	Protein conserved in bacteria
E1950_RS03830	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E1950_RS03845	COG2011	ABC-type metal ion transport system permease component
E1950_RS03850	COG1464	Belongs to the NlpA lipoprotein family
E1950_RS03865	COG0396	ATPase activity
E1950_RS03870	COG0719	Fe-S assembly protein
E1950_RS03880	COG0822	iron-sulfur transferase activity
E1950_RS03990	COG1484	DNA-dependent DNA replication
E1950_RS04210	COG1388	LysM domain
E1950_RS04210	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1950_RS04235	COG1253	flavin adenine dinucleotide binding
E1950_RS04250	COG1801	Protein of unknown function DUF72
E1950_RS04255	COG0730	response to heat
E1950_RS04270	COG4470	Protein conserved in bacteria
E1950_RS04280	COG2445	Protein of unknown function DUF86
E1950_RS04310	COG1696	Membrane protein involved in D-alanine export
E1950_RS04320	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E1950_RS04325	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E1950_RS04330	COG4837	Protein of unknown function (DUF1462)
E1950_RS04335	COG1252	NADH dehydrogenase
E1950_RS04345	COG0316	Belongs to the HesB IscA family
E1950_RS04355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E1950_RS04360	COG2056	Na+-H+ antiporter family
E1950_RS04365	COG2050	protein possibly involved in aromatic compounds catabolism
E1950_RS04420	COG1098	S1 RNA binding domain
E1950_RS04425	COG1902	pentaerythritol trinitrate reductase activity
E1950_RS04440	COG0584	glycerophosphoryl diester phosphodiesterase
E1950_RS04460	COG0398	Pfam SNARE associated Golgi protein
E1950_RS04500	COG0561	phosphatase activity
E1950_RS04525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E1950_RS04540	COG1881	PFAM PEBP family protein
E1950_RS04570	COG0601	transmembrane transport
E1950_RS04575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1950_RS04580	COG0444	Belongs to the ABC transporter superfamily
E1950_RS04585	COG4608	Belongs to the ABC transporter superfamily
E1950_RS04590	COG4166	transmembrane transport
E1950_RS04595	COG0747	negative chemotaxis
E1950_RS04600	COG0444	Belongs to the ABC transporter superfamily
E1950_RS04605	COG4608	Belongs to the ABC transporter superfamily
E1950_RS04610	COG0601	transmembrane transport
E1950_RS04615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1950_RS04640	COG1164	Oligoendopeptidase f
E1950_RS04650	COG2346	COG2346, Truncated hemoglobins
E1950_RS04665	COG2357	RelA SpoT domain protein
E1950_RS04675	COG0564	pseudouridine synthase activity
E1950_RS04680	COG2239	Acts as a magnesium transporter
E1950_RS04685	COG0475	glutathione-regulated potassium exporter activity
E1950_RS04685	COG0569	domain protein
E1950_RS04695	COG0628	permease
E1950_RS04700	COG1115	amino acid carrier protein
E1950_RS04740	COG0861	Integral membrane protein TerC family
E1950_RS04750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E1950_RS04755	COG0737	Belongs to the 5'-nucleotidase family
E1950_RS04770	COG4903	ComK protein
E1950_RS04785	COG4873	Protein conserved in bacteria
E1950_RS04840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E1950_RS04850	COG2314	TM2 domain
E1950_RS04855	COG0456	acetyltransferase
E1950_RS04860	COG1575	Belongs to the MenA family. Type 1 subfamily
E1950_RS04870	COG1169	isochorismate synthase
E1950_RS04880	COG2267	carboxylic ester hydrolase activity
E1950_RS04905	COG0436	Aminotransferase
E1950_RS04910	COG3594	Acyltransferase
E1950_RS04940	COG1316	TRANSCRIPTIONal
E1950_RS04985	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E1950_RS05000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E1950_RS05040	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E1950_RS05045	COG4172	Belongs to the ABC transporter superfamily
E1950_RS05050	COG4721	ABC-type cobalt transport system, permease component
E1950_RS05075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E1950_RS05095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E1950_RS05100	COG1271	oxidase subunit
E1950_RS05105	COG1294	oxidase, subunit
E1950_RS05110	COG0569	domain protein
E1950_RS05175	COG1176	ABC-type spermidine putrescine transport system, permease component I
E1950_RS05180	COG1177	transmembrane transport
E1950_RS05185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E1950_RS05210	COG0483	inositol monophosphate 1-phosphatase activity
E1950_RS05220	COG1217	gtp-binding protein TYPA
E1950_RS05230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E1950_RS05240	COG0772	Belongs to the SEDS family
E1950_RS05270	COG3679	Belongs to the UPF0342 family
E1950_RS05290	COG0742	ribosomal rna small subunit methyltransferase
E1950_RS05350	COG4509	Sortase family
E1950_RS05365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E1950_RS05395	COG1796	DNA polymerase
E1950_RS05395	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E1950_RS05420	COG2009	succinate dehydrogenase
E1950_RS05425	COG1053	succinate dehydrogenase
E1950_RS05430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E1950_RS05550	COG1288	antiporter activity
E1950_RS05585	COG1011	Hydrolase
E1950_RS05610	COG4839	cell division protein FtsL
E1950_RS05615	COG0768	penicillin binding
E1950_RS05630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E1950_RS05635	COG0849	cell division
E1950_RS05650	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E1950_RS05660	COG0762	integral membrane protein
E1950_RS05665	COG2302	S4 RNA-binding domain
E1950_RS05670	COG3599	regulation of cell shape
E1950_RS05680	COG2514	catechol 2,3-dioxygenase activity
E1950_RS05700	COG0564	pseudouridine synthase activity
E1950_RS05710	COG2233	PERMEase
E1950_RS05755	COG1293	RNA-binding protein homologous to eukaryotic snRNP
E1950_RS05770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E1950_RS05775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E1950_RS05785	COG2314	TM2 domain
E1950_RS05800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E1950_RS05800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E1950_RS05810	COG0631	protein serine/threonine phosphatase activity
E1950_RS05825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E1950_RS05840	COG1302	Protein conserved in bacteria
E1950_RS05885	COG1196	nuclear chromosome segregation
E1950_RS05890	COG0552	protein localization to endoplasmic reticulum
E1950_RS05900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E1950_RS05955	COG2348	transferase activity, transferring amino-acyl groups
E1950_RS06055	COG0195	Participates in both transcription termination and antitermination
E1950_RS06060	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E1950_RS06085	COG0196	riboflavin kinase activity
E1950_RS06110	COG2188	Transcriptional regulator
E1950_RS06115	COG0612	Peptidase, M16
E1950_RS06120	COG0612	Peptidase, M16
E1950_RS06125	COG0300	oxidoreductase activity
E1950_RS06145	COG1546	Belongs to the CinA family
E1950_RS06145	COG1058	Belongs to the CinA family
E1950_RS06165	COG1692	metallophosphoesterase
E1950_RS06170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E1950_RS06170	COG0674	pyruvate-flavodoxin oxidoreductase activity
E1950_RS06175	COG1013	pyruvate-flavodoxin oxidoreductase activity
E1950_RS06210	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E1950_RS06215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E1950_RS06240	COG1923	regulation of RNA biosynthetic process
E1950_RS06250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E1950_RS06255	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E1950_RS06260	COG0789	Transcriptional regulator
E1950_RS06345	COG1131	(ABC) transporter
E1950_RS06360	COG2197	response regulator
E1950_RS06370	COG1525	nuclease
E1950_RS06385	COG0527	aspartate kinase activity
E1950_RS06390	COG0460	homoserine dehydrogenase
E1950_RS06395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E1950_RS06420	COG0833	amino acid
E1950_RS06450	COG2340	Cysteine-rich secretory protein family
E1950_RS06485	COG4846	Membrane protein involved in cytochrome C biogenesis
E1950_RS06505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E1950_RS06520	COG0824	Thioesterase
E1950_RS06550	COG1115	amino acid carrier protein
E1950_RS06565	COG0628	permease
E1950_RS06590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E1950_RS06600	COG1363	Peptidase, m42
E1950_RS06605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E1950_RS06610	COG0512	Glutamine amidotransferase of anthranilate synthase
E1950_RS06655	COG0561	phosphatase activity
E1950_RS06700	COG0704	Plays a role in the regulation of phosphate uptake
E1950_RS06710	COG0581	inorganic phosphate transmembrane transporter activity
E1950_RS06715	COG0573	inorganic phosphate transmembrane transporter activity
E1950_RS06735	COG0488	(ABC) transporter
E1950_RS06740	COG0527	aspartate kinase activity
E1950_RS06745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E1950_RS06820	COG4548	von Willebrand factor, type A
E1950_RS06825	COG0714	Associated with various cellular activities
E1950_RS06870	COG0671	phosphoesterase, PA-phosphatase related
E1950_RS06945	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E1950_RS06965	COG0531	amino acid
E1950_RS06980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E1950_RS06985	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E1950_RS07000	COG0116	Belongs to the methyltransferase superfamily
E1950_RS07040	COG4499	WXG100 protein secretion system (Wss), protein YukC
E1950_RS07040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E1950_RS07050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E1950_RS07055	COG3935	DnaD domain protein
E1950_RS07080	COG0438	transferase activity, transferring glycosyl groups
E1950_RS07085	COG1694	Mazg nucleotide pyrophosphohydrolase
E1950_RS07090	COG2738	Putative neutral zinc metallopeptidase
E1950_RS07095	COG4347	Protein of unknown function (DUF1405)
E1950_RS07135	COG0142	geranyltranstransferase activity
E1950_RS07190	COG0492	ferredoxin-NADP+ reductase activity
E1950_RS07205	COG0514	ATP-dependent DNA helicase (RecQ)
E1950_RS07215	COG1141	Ferredoxin
E1950_RS07260	COG0745	RESPONSE REGULATOR receiver
E1950_RS07265	COG1187	pseudouridine synthase activity
E1950_RS07290	COG0735	belongs to the Fur family
E1950_RS07295	COG0494	nUDIX hydrolase
E1950_RS07300	COG0667	Aldo Keto reductase
E1950_RS07310	COG4221	oxidoreductase activity
E1950_RS07325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E1950_RS07335	COG0366	Alpha amylase catalytic
E1950_RS07340	COG1609	Transcriptional regulator
E1950_RS07365	COG2195	Cleaves the N-terminal amino acid of tripeptides
E1950_RS07375	COG4129	membrane
E1950_RS07385	COG0508	dehydrogenase complex catalyzes the overall conversion of
E1950_RS07390	COG0022	dehydrogenase e1 component
E1950_RS07395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E1950_RS07400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E1950_RS07405	COG0497	DNA recombination
E1950_RS07435	COG1302	Protein conserved in bacteria
E1950_RS07440	COG0439	Biotin carboxylase
E1950_RS07445	COG0511	ligase activity, forming carbon-carbon bonds
E1950_RS07455	COG0006	proline dipeptidase activity
E1950_RS07470	COG0095	Lipoate-protein ligase
E1950_RS07475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1950_RS07520	COG4537	Required for transformation and DNA binding
E1950_RS07525	COG1459	type II secretion system
E1950_RS07530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E1950_RS07535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1950_RS07540	COG0011	TIGRFAM Protein of
E1950_RS07545	COG1940	carbohydrate kinase activity
E1950_RS07550	COG4483	Protein conserved in bacteria
E1950_RS07560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E1950_RS07570	COG0768	penicillin binding
E1950_RS07585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E1950_RS07590	COG1121	(ABC) transporter
E1950_RS07600	COG0513	Belongs to the DEAD box helicase family
E1950_RS07610	COG2384	SAM-dependent methyltransferase
E1950_RS07630	COG0517	IMP dehydrogenase activity
E1950_RS07650	COG0295	cytidine deaminase activity
E1950_RS07665	COG1702	phosphate starvation-inducible protein PhoH
E1950_RS07680	COG1030	water channel activity
E1950_RS07690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E1950_RS07695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E1950_RS07725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E1950_RS07740	COG1466	dna polymerase III delta subunit
E1950_RS07745	COG0658	competence protein
E1950_RS07745	COG2333	competence protein COMEC
E1950_RS07750	COG2131	deaminase
E1950_RS07755	COG2183	response to ionizing radiation
E1950_RS07760	COG2226	methyltransferase
E1950_RS07765	COG0799	negative regulation of ribosome biogenesis
E1950_RS07770	COG1713	HD superfamily hydrolase involved in NAD metabolism
E1950_RS07780	COG1534	Rna-binding protein
E1950_RS07790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E1950_RS07795	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E1950_RS07825	COG3177	Filamentation induced by cAMP protein fic
E1950_RS07830	COG1914	H( )-stimulated, divalent metal cation uptake system
E1950_RS07840	COG0439	Biotin carboxylase
E1950_RS07845	COG0511	ligase activity, forming carbon-carbon bonds
E1950_RS07850	COG1984	allophanate hydrolase subunit 2
E1950_RS07855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E1950_RS07870	COG0826	peptidase U32
E1950_RS07875	COG0826	peptidase U32
E1950_RS07905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E1950_RS07920	COG1104	cysteine desulfurase activity
E1950_RS07925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E1950_RS07935	COG3237	CsbD-like
E1950_RS07940	COG1959	2 iron, 2 sulfur cluster binding
E1950_RS07945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E1950_RS07950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E1950_RS07995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E1950_RS07995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E1950_RS08000	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E1950_RS08000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E1950_RS08005	COG1862	Preprotein translocase
E1950_RS08045	COG2868	ribosomal protein
E1950_RS08090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E1950_RS08095	COG0285	dihydrofolate synthase activity
E1950_RS08105	COG2818	Glycosylase
E1950_RS08140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E1950_RS08175	COG4112	unkown
E1950_RS08195	COG0833	amino acid
E1950_RS08210	COG1484	DNA-dependent DNA replication
E1950_RS08240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E1950_RS08240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E1950_RS08255	COG0745	RESPONSE REGULATOR receiver
E1950_RS08265	COG0372	Belongs to the citrate synthase family
E1950_RS08270	COG1113	amino acid transport
E1950_RS08295	COG0281	malic enzyme
E1950_RS08305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E1950_RS08310	COG4109	DRTGG domain
E1950_RS08350	COG0827	DNA restriction-modification system
E1950_RS08360	COG0730	response to heat
E1950_RS08370	COG1104	cysteine desulfurase activity
E1950_RS08385	COG1956	GAF domain-containing protein
E1950_RS08400	COG0584	glycerophosphoryl diester phosphodiesterase
E1950_RS08405	COG1764	response to oxidative stress
E1950_RS08410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E1950_RS08415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E1950_RS08430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1950_RS08430	COG1263	PTS System
E1950_RS08435	COG0204	Acyl-transferase
E1950_RS08440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E1950_RS08475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E1950_RS08480	COG0454	-acetyltransferase
E1950_RS08500	COG1605	Chorismate mutase
E1950_RS08500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E1950_RS08525	COG1674	ftsk spoiiie
E1950_RS08530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E1950_RS08540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1950_RS08545	COG1363	Peptidase, m42
E1950_RS08555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1950_RS08565	COG0510	thiamine kinase activity
E1950_RS08585	COG1187	pseudouridine synthase activity
E1950_RS08590	COG2244	polysaccharide biosynthetic process
E1950_RS08595	COG2081	HI0933 family
E1950_RS08615	COG2814	Major facilitator Superfamily
E1950_RS08620	COG1242	4 iron, 4 sulfur cluster binding
E1950_RS08625	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E1950_RS08635	COG2267	carboxylic ester hydrolase activity
E1950_RS08665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E1950_RS08665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E1950_RS08685	COG3266	domain, Protein
E1950_RS08685	COG4193	domain, Protein
E1950_RS08685	COG5632	N-Acetylmuramoyl-L-alanine amidase
E1950_RS08715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E1950_RS08740	COG0656	L-ascorbic acid biosynthetic process
E1950_RS08760	COG1506	peptidase
E1950_RS08765	COG2816	NAD+ diphosphatase activity
E1950_RS09025	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
E1950_RS09055	COG1131	(ABC) transporter
E1950_RS09060	COG0537	adenosine 5'-monophosphoramidase activity
E1950_RS09090	COG0420	3'-5' exonuclease activity
E1950_RS09120	COG2197	response regulator
E1950_RS09125	COG2203	Gaf domain
E1950_RS09125	COG4585	Histidine kinase
E1950_RS09130	COG0564	pseudouridine synthase activity
E1950_RS09160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E1950_RS09165	COG1126	abc transporter atp-binding protein
E1950_RS09170	COG0765	amino acid transport
E1950_RS09185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E1950_RS09190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E1950_RS09200	COG4129	membrane
E1950_RS09225	COG1988	membrane-bound metal-dependent
E1950_RS09240	COG1388	LysM domain
E1950_RS09240	COG1134	teichoic acid transport
E1950_RS09270	COG0535	radical SAM domain protein
E1950_RS09275	COG1607	acyl-coa hydrolase
E1950_RS09280	COG2309	aminopeptidase activity
E1950_RS09300	COG1295	ribonuclease BN
E1950_RS09415	COG4851	CamS sex pheromone cAM373 precursor
E1950_RS09435	COG4496	protein, YerC YecD
E1950_RS09475	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E1950_RS09485	COG0077	Prephenate dehydratase
E1950_RS09495	COG0471	metal ion transport
E1950_RS09505	COG1335	isochorismatase
E1950_RS09520	COG1012	belongs to the aldehyde dehydrogenase family
E1950_RS09575	COG1131	(ABC) transporter
E1950_RS09590	COG1725	Transcriptional regulator
E1950_RS09645	COG1388	LysM domain
E1950_RS09645	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1950_RS09670	COG1388	LysM domain
E1950_RS09670	COG5632	N-Acetylmuramoyl-L-alanine amidase
E1950_RS09770	COG4695	Portal protein
E1950_RS09940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E1950_RS09990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E1950_RS10060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1950_RS10065	COG1621	beta-fructofuranosidase activity
E1950_RS10070	COG1609	Transcriptional regulator
E1950_RS10075	COG0004	ammonium transporteR
E1950_RS10080	COG0425	Belongs to the sulfur carrier protein TusA family
E1950_RS10085	COG2391	methyltransferase activity
E1950_RS10095	COG0488	(ABC) transporter
E1950_RS10105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E1950_RS10115	COG0456	acetyltransferase
E1950_RS10120	COG1214	PFAM Peptidase M22, glycoprotease
E1950_RS10125	COG0802	atpase or kinase
E1950_RS10140	COG0028	Belongs to the TPP enzyme family
E1950_RS10205	COG2183	response to ionizing radiation
E1950_RS10210	COG1191	sigma factor activity
E1950_RS10220	COG1366	Belongs to the anti-sigma-factor antagonist family
E1950_RS10225	COG2208	phosphoserine phosphatase activity
E1950_RS10255	COG3428	Bacterial PH domain
E1950_RS10285	COG2205	protein histidine kinase activity
E1950_RS10290	COG0745	RESPONSE REGULATOR receiver
E1950_RS10300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E1950_RS10310	COG0772	Belongs to the SEDS family
E1950_RS10325	COG1937	Protein conserved in bacteria
E1950_RS10335	COG1418	mRNA catabolic process
E1950_RS10390	COG0629	single-stranded DNA binding
E1950_RS10465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E1950_RS10490	COG0009	L-threonylcarbamoyladenylate synthase
E1950_RS10495	COG2890	protein-(glutamine-N5) methyltransferase activity
E1950_RS10520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E1950_RS10560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1950_RS10605	COG0813	purine-nucleoside phosphorylase activity
E1950_RS10610	COG0783	Belongs to the Dps family
E1950_RS10630	COG1482	cell wall glycoprotein biosynthetic process
E1950_RS10635	COG0702	epimerase
E1950_RS10640	COG0640	Transcriptional regulator
E1950_RS10675	COG0561	phosphatase activity
E1950_RS10680	COG1119	ATPase activity
E1950_RS10695	COG3711	transcriptional antiterminator
E1950_RS10725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E1950_RS10780	COG0489	protein tyrosine kinase activity
E1950_RS10785	COG2814	Major facilitator Superfamily
E1950_RS10800	COG1272	protein, Hemolysin III
E1950_RS10810	COG1988	membrane-bound metal-dependent
E1950_RS10820	COG3314	Sporulation integral membrane protein YlbJ
E1950_RS10825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1950_RS10830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1950_RS10835	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E1950_RS10845	COG3457	Alanine racemase
E1950_RS10850	COG4264	IucA IucC family
E1950_RS10855	COG2814	Major facilitator Superfamily
E1950_RS10880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E1950_RS10890	COG2130	NADP-dependent
E1950_RS10955	COG0656	L-ascorbic acid biosynthetic process
E1950_RS10960	COG0789	Transcriptional regulator
E1950_RS10970	COG5492	domain, Protein
E1950_RS10990	COG3527	Alpha-acetolactate decarboxylase
E1950_RS10995	COG0028	Belongs to the TPP enzyme family
E1950_RS11110	COG0201	protein transport
E1950_RS11225	COG2252	PERMEase
E1950_RS11270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E1950_RS11330	COG1763	Mo-molybdopterin cofactor biosynthetic process
E1950_RS11350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E1950_RS11355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E1950_RS11360	COG4149	molybdate abc transporter
E1950_RS11365	COG0725	ABC transporter, periplasmic molybdate-binding protein
E1950_RS11380	COG1268	BioY protein
E1950_RS11395	COG1960	acyl-CoA dehydrogenase activity
E1950_RS11400	COG4413	Urea transporter
E1950_RS11460	COG3942	CHAP domain
E1950_RS11470	COG1757	Na H antiporter
E1950_RS11485	COG3942	CHAP domain
E1950_RS11555	COG1113	amino acid transport
E1950_RS11575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E1950_RS11580	COG0385	Bile acid
E1950_RS11590	COG1263	PTS System
E1950_RS11590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1950_RS11595	COG1737	Transcriptional regulator
E1950_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
E1950_RS11620	COG1473	amidohydrolase
E1950_RS11635	COG0583	DNA-binding transcription factor activity
E1950_RS11660	COG2258	MOSC domain
E1950_RS11680	COG1668	transmembrane transport
E1950_RS11685	COG4152	abc transporter atp-binding protein
E1950_RS11690	COG3152	Membrane
E1950_RS11705	COG0786	glutamate:sodium symporter activity
E1950_RS11715	COG0598	Magnesium transport protein CorA
E1950_RS11730	COG0657	acetylesterase activity
E1950_RS11740	COG2814	Major facilitator Superfamily
E1950_RS11745	COG1566	PFAM secretion protein HlyD family protein
E1950_RS11755	COG2814	Major facilitator Superfamily
E1950_RS11815	COG1620	l-lactate permease
E1950_RS11835	COG0604	alcohol dehydrogenase
E1950_RS11875	COG1511	domain protein
E1950_RS11890	COG1263	PTS System
E1950_RS11890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1950_RS11905	COG3871	stress protein (general stress protein 26)
E1950_RS11945	COG0789	Transcriptional regulator
E1950_RS11965	COG2181	nitrate reductase activity
E1950_RS11975	COG1140	nitrate reductase beta subunit
E1950_RS11980	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E1950_RS11990	COG2146	nitrite reductase [NAD(P)H] activity
E1950_RS11995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E1950_RS12005	COG0454	-acetyltransferase
E1950_RS12010	COG2116	formate transmembrane transporter activity
E1950_RS12025	COG3443	Belongs to the bacterial solute-binding protein 9 family
E1950_RS12025	COG0803	Belongs to the bacterial solute-binding protein 9 family
E1950_RS12065	COG1126	abc transporter atp-binding protein
E1950_RS12070	COG0765	amino acid transport
E1950_RS12075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1950_RS12080	COG2814	Major facilitator Superfamily
E1950_RS12095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E1950_RS12140	COG0156	8-amino-7-oxononanoate synthase activity
E1950_RS12150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E1950_RS12155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E1950_RS12165	COG1132	(ABC) transporter
E1950_RS12170	COG1132	(ABC) transporter
E1950_RS12170	COG2375	cellular response to nickel ion
E1950_RS12185	COG1929	Belongs to the glycerate kinase type-1 family
E1950_RS12195	COG2814	Major facilitator Superfamily
E1950_RS12215	COG1113	amino acid transport
E1950_RS12240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E1950_RS12250	COG1174	glycine betaine transport
E1950_RS12260	COG1174	glycine betaine transport
E1950_RS12280	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E1950_RS12285	COG0531	amino acid
E1950_RS12290	COG2272	Belongs to the type-B carboxylesterase lipase family
E1950_RS12295	COG2814	Major facilitator Superfamily
E1950_RS12300	COG0390	transport system, permease component
E1950_RS12305	COG4619	ABC transporter
E1950_RS12310	COG1363	Peptidase, m42
E1950_RS12330	COG4808	Protein conserved in bacteria
E1950_RS12335	COG0069	glutamate synthase activity
E1950_RS12390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E1950_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
E1950_RS12400	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E1950_RS12405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1950_RS12505	COG0494	nUDIX hydrolase
E1950_RS12550	COG1846	Transcriptional regulator
E1950_RS12585	COG1070	Carbohydrate kinase
E1950_RS12590	COG1802	Transcriptional regulator
E1950_RS12595	COG0789	Transcriptional regulator
E1950_RS12600	COG2357	RelA SpoT domain protein
E1950_RS12605	COG4876	unkown
E1950_RS12615	COG2271	Major facilitator Superfamily
E1950_RS12620	COG0586	Pfam SNARE associated Golgi protein
E1950_RS12640	COG1131	(ABC) transporter
E1950_RS12660	COG0400	carboxylic ester hydrolase activity
E1950_RS12665	COG0346	lactoylglutathione lyase activity
E1950_RS12670	COG1846	Transcriptional regulator
E1950_RS12680	COG2514	catechol 2,3-dioxygenase activity
E1950_RS12695	COG0561	phosphatase activity
E1950_RS12700	COG1131	(ABC) transporter
E1950_RS12710	COG3764	Sortase (surface protein transpeptidase)
E1950_RS12730	COG1760	l-serine dehydratase
E1950_RS12735	COG1760	l-serine dehydratase
E1950_RS12755	COG0657	acetylesterase activity
E1950_RS12775	COG0028	Belongs to the TPP enzyme family
E1950_RS12790	COG0583	DNA-binding transcription factor activity
E1950_RS12800	COG3942	CHAP domain
E1950_RS12810	COG3425	synthase
E1950_RS12815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E1950_RS12840	COG2409	Drug exporters of the RND superfamily
E1950_RS12885	COG0436	Aminotransferase
E1950_RS12915	COG3942	CHAP domain
E1950_RS12920	COG2755	lipolytic protein G-D-S-L family
E1950_RS12920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
E1950_RS13030	COG3001	Fructosamine kinase
E1950_RS13035	COG0167	dihydroorotate dehydrogenase activity
E1950_RS13090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E1950_RS13095	COG3527	Alpha-acetolactate decarboxylase
E1950_RS13105	COG0531	amino acid
E1950_RS13135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E1950_RS13155	COG1012	belongs to the aldehyde dehydrogenase family
E1950_RS13165	COG1510	regulation of RNA biosynthetic process
E1950_RS13170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E1950_RS13195	COG2851	Citrate transporter
E1950_RS13210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E1950_RS13220	COG0386	Belongs to the glutathione peroxidase family
E1950_RS13245	COG1136	(ABC) transporter
E1950_RS13250	COG2205	protein histidine kinase activity
E1950_RS13255	COG0745	RESPONSE REGULATOR receiver
E1950_RS13265	COG1785	Belongs to the alkaline phosphatase family
E1950_RS13275	COG1846	Transcriptional regulator
E1950_RS13320	COG1438	arginine binding
E1950_RS13340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1950_RS13340	COG3711	transcriptional antiterminator
E1950_RS13345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1950_RS13345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1950_RS13345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1950_RS13350	COG1482	cell wall glycoprotein biosynthetic process
E1950_RS13360	COG1705	Flagellar rod assembly protein muramidase FlgJ
E1950_RS13360	COG3942	CHAP domain
E1950_RS13365	COG3433	isochorismatase activity
E1950_RS13365	COG1535	isochorismatase
E1950_RS13380	COG0438	transferase activity, transferring glycosyl groups
E1950_RS13395	COG1073	alpha beta
E1950_RS13415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E1950_RS13435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E1950_RS13525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E1950_RS13610	COG0471	metal ion transport
E1950_RS13615	COG2962	Rard protein
E1950_RS13625	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E1950_RS13640	COG1136	(ABC) transporter
E1950_RS13645	COG0577	efflux transmembrane transporter activity
E1950_RS13655	COG1278	Cold shock
E1950_RS13675	COG1475	DNA binding
E1950_RS13715	COG2501	S4 domain
E1950_RS13735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E1950_RS13760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E1950_RS13770	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E1950_RS13780	COG0305	Participates in initiation and elongation during chromosome replication
E1950_RS13810	COG4863	YycH protein
E1950_RS13820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E1950_RS13825	COG0737	Belongs to the 5'-nucleotidase family
E1950_RS13850	COG2030	dehydratase
E1950_RS13855	COG0584	glycerophosphoryl diester phosphodiesterase
E1950_RS13865	COG3425	synthase
E1950_RS13905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E1950_RS13935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
E1950_RS13945	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E1950_RS14095	COG0456	acetyltransferase
E1950_RS14325	COG0604	alcohol dehydrogenase