locus-tag	class	description
RK72_RS00085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK72_RS00090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RK72_RS00100	COG4129	membrane
RK72_RS00125	COG1988	membrane-bound metal-dependent
RK72_RS00140	COG1134	teichoic acid transport
RK72_RS00140	COG1388	LysM domain
RK72_RS00170	COG0535	radical SAM domain protein
RK72_RS00175	COG1607	acyl-coa hydrolase
RK72_RS00180	COG2309	aminopeptidase activity
RK72_RS00200	COG1295	ribonuclease BN
RK72_RS00325	COG4851	CamS sex pheromone cAM373 precursor
RK72_RS00345	COG4496	protein, YerC YecD
RK72_RS00385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RK72_RS00395	COG0077	Prephenate dehydratase
RK72_RS00405	COG0471	metal ion transport
RK72_RS00415	COG1335	isochorismatase
RK72_RS00430	COG1012	belongs to the aldehyde dehydrogenase family
RK72_RS00485	COG1131	(ABC) transporter
RK72_RS00500	COG1725	Transcriptional regulator
RK72_RS00560	COG1388	LysM domain
RK72_RS00560	COG0860	N-Acetylmuramoyl-L-alanine amidase
RK72_RS00575	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK72_RS00575	COG1388	LysM domain
RK72_RS00620	COG0739	heme binding
RK72_RS00675	COG4695	Portal protein
RK72_RS00790	COG1484	DNA-dependent DNA replication
RK72_RS00920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK72_RS00990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK72_RS00995	COG1621	beta-fructofuranosidase activity
RK72_RS01000	COG1609	Transcriptional regulator
RK72_RS01005	COG0004	ammonium transporteR
RK72_RS01010	COG0425	Belongs to the sulfur carrier protein TusA family
RK72_RS01015	COG2391	methyltransferase activity
RK72_RS01025	COG0488	(ABC) transporter
RK72_RS01035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK72_RS01045	COG0456	acetyltransferase
RK72_RS01050	COG1214	PFAM Peptidase M22, glycoprotease
RK72_RS01055	COG0802	atpase or kinase
RK72_RS01070	COG0028	Belongs to the TPP enzyme family
RK72_RS01145	COG2183	response to ionizing radiation
RK72_RS01150	COG1191	sigma factor activity
RK72_RS01160	COG1366	Belongs to the anti-sigma-factor antagonist family
RK72_RS01165	COG2208	phosphoserine phosphatase activity
RK72_RS01200	COG3428	Bacterial PH domain
RK72_RS01230	COG2205	protein histidine kinase activity
RK72_RS01235	COG0745	RESPONSE REGULATOR receiver
RK72_RS01255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RK72_RS01265	COG0772	Belongs to the SEDS family
RK72_RS01280	COG1937	Protein conserved in bacteria
RK72_RS01290	COG1418	mRNA catabolic process
RK72_RS01345	COG0629	single-stranded DNA binding
RK72_RS01420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK72_RS01445	COG0009	L-threonylcarbamoyladenylate synthase
RK72_RS01450	COG2890	protein-(glutamine-N5) methyltransferase activity
RK72_RS01475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RK72_RS01515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK72_RS01565	COG0813	purine-nucleoside phosphorylase activity
RK72_RS01570	COG0783	Belongs to the Dps family
RK72_RS01590	COG1482	cell wall glycoprotein biosynthetic process
RK72_RS01595	COG0702	epimerase
RK72_RS01600	COG0640	Transcriptional regulator
RK72_RS01635	COG0561	phosphatase activity
RK72_RS01640	COG1119	ATPase activity
RK72_RS01655	COG3711	transcriptional antiterminator
RK72_RS01685	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RK72_RS01745	COG0489	protein tyrosine kinase activity
RK72_RS01750	COG2814	Major facilitator Superfamily
RK72_RS01765	COG1272	protein, Hemolysin III
RK72_RS01775	COG1988	membrane-bound metal-dependent
RK72_RS01785	COG3314	Sporulation integral membrane protein YlbJ
RK72_RS01790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK72_RS01795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK72_RS01800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK72_RS01810	COG3457	Alanine racemase
RK72_RS01815	COG4264	IucA IucC family
RK72_RS01820	COG2814	Major facilitator Superfamily
RK72_RS01845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK72_RS01855	COG2130	NADP-dependent
RK72_RS01920	COG0656	L-ascorbic acid biosynthetic process
RK72_RS01925	COG0789	Transcriptional regulator
RK72_RS01935	COG5492	domain, Protein
RK72_RS01955	COG3527	Alpha-acetolactate decarboxylase
RK72_RS01960	COG0028	Belongs to the TPP enzyme family
RK72_RS02075	COG0201	protein transport
RK72_RS02190	COG2252	PERMEase
RK72_RS02240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK72_RS02310	COG1763	Mo-molybdopterin cofactor biosynthetic process
RK72_RS02330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RK72_RS02335	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RK72_RS02340	COG4149	molybdate abc transporter
RK72_RS02345	COG0725	ABC transporter, periplasmic molybdate-binding protein
RK72_RS02360	COG1268	BioY protein
RK72_RS02375	COG1960	acyl-CoA dehydrogenase activity
RK72_RS02380	COG4413	Urea transporter
RK72_RS02445	COG3942	CHAP domain
RK72_RS02455	COG1757	Na H antiporter
RK72_RS02470	COG3942	CHAP domain
RK72_RS02540	COG1113	amino acid transport
RK72_RS02560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK72_RS02565	COG0385	Bile acid
RK72_RS02575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK72_RS02575	COG1263	PTS System
RK72_RS02580	COG1737	Transcriptional regulator
RK72_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
RK72_RS02605	COG1473	amidohydrolase
RK72_RS02620	COG0583	DNA-binding transcription factor activity
RK72_RS02645	COG2258	MOSC domain
RK72_RS02665	COG1668	transmembrane transport
RK72_RS02670	COG4152	abc transporter atp-binding protein
RK72_RS02675	COG3152	Membrane
RK72_RS02695	COG0786	glutamate:sodium symporter activity
RK72_RS02705	COG0598	Magnesium transport protein CorA
RK72_RS02720	COG0657	acetylesterase activity
RK72_RS02730	COG2814	Major facilitator Superfamily
RK72_RS02735	COG1566	PFAM secretion protein HlyD family protein
RK72_RS02745	COG2814	Major facilitator Superfamily
RK72_RS02810	COG1620	l-lactate permease
RK72_RS02830	COG0604	alcohol dehydrogenase
RK72_RS02860	COG1511	domain protein
RK72_RS02875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK72_RS02875	COG1263	PTS System
RK72_RS02890	COG3871	stress protein (general stress protein 26)
RK72_RS02930	COG0789	Transcriptional regulator
RK72_RS02950	COG2181	nitrate reductase activity
RK72_RS02960	COG1140	nitrate reductase beta subunit
RK72_RS02965	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RK72_RS02975	COG2146	nitrite reductase [NAD(P)H] activity
RK72_RS02980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RK72_RS02990	COG0454	-acetyltransferase
RK72_RS02995	COG2116	formate transmembrane transporter activity
RK72_RS03010	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK72_RS03010	COG3443	Belongs to the bacterial solute-binding protein 9 family
RK72_RS03050	COG1126	abc transporter atp-binding protein
RK72_RS03055	COG0765	amino acid transport
RK72_RS03060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK72_RS03065	COG2814	Major facilitator Superfamily
RK72_RS03085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RK72_RS03135	COG0156	8-amino-7-oxononanoate synthase activity
RK72_RS03145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RK72_RS03150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RK72_RS03165	COG1132	(ABC) transporter
RK72_RS03170	COG1132	(ABC) transporter
RK72_RS03170	COG2375	cellular response to nickel ion
RK72_RS03190	COG1929	Belongs to the glycerate kinase type-1 family
RK72_RS03200	COG2814	Major facilitator Superfamily
RK72_RS03220	COG1113	amino acid transport
RK72_RS03235	COG0531	amino acid
RK72_RS03260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK72_RS03270	COG1174	glycine betaine transport
RK72_RS03280	COG1174	glycine betaine transport
RK72_RS03300	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RK72_RS03310	COG0531	amino acid
RK72_RS03315	COG2272	Belongs to the type-B carboxylesterase lipase family
RK72_RS03320	COG2814	Major facilitator Superfamily
RK72_RS03325	COG0390	transport system, permease component
RK72_RS03330	COG4619	ABC transporter
RK72_RS03335	COG1363	Peptidase, m42
RK72_RS03355	COG4808	Protein conserved in bacteria
RK72_RS03360	COG0069	glutamate synthase activity
RK72_RS03415	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RK72_RS03420	COG1028	Short-chain dehydrogenase reductase Sdr
RK72_RS03425	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RK72_RS03430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK72_RS03525	COG0494	nUDIX hydrolase
RK72_RS03570	COG1846	Transcriptional regulator
RK72_RS03605	COG1070	Carbohydrate kinase
RK72_RS03610	COG1802	Transcriptional regulator
RK72_RS03615	COG0789	Transcriptional regulator
RK72_RS03620	COG2357	RelA SpoT domain protein
RK72_RS03625	COG4876	unkown
RK72_RS03635	COG2271	Major facilitator Superfamily
RK72_RS03640	COG0586	Pfam SNARE associated Golgi protein
RK72_RS03660	COG1131	(ABC) transporter
RK72_RS03680	COG0400	carboxylic ester hydrolase activity
RK72_RS03685	COG0346	lactoylglutathione lyase activity
RK72_RS03690	COG1846	Transcriptional regulator
RK72_RS03700	COG2514	catechol 2,3-dioxygenase activity
RK72_RS03715	COG0561	phosphatase activity
RK72_RS03720	COG1131	(ABC) transporter
RK72_RS03730	COG3764	Sortase (surface protein transpeptidase)
RK72_RS03750	COG1760	l-serine dehydratase
RK72_RS03755	COG1760	l-serine dehydratase
RK72_RS03770	COG0697	spore germination
RK72_RS03775	COG0657	acetylesterase activity
RK72_RS03795	COG0028	Belongs to the TPP enzyme family
RK72_RS03810	COG0583	DNA-binding transcription factor activity
RK72_RS03820	COG3942	CHAP domain
RK72_RS03830	COG3425	synthase
RK72_RS03835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RK72_RS03860	COG2409	Drug exporters of the RND superfamily
RK72_RS03905	COG0436	Aminotransferase
RK72_RS03935	COG3942	CHAP domain
RK72_RS03940	COG2755	lipolytic protein G-D-S-L family
RK72_RS03940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RK72_RS04050	COG3001	Fructosamine kinase
RK72_RS04055	COG0167	dihydroorotate dehydrogenase activity
RK72_RS04110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK72_RS04115	COG3527	Alpha-acetolactate decarboxylase
RK72_RS04130	COG0531	amino acid
RK72_RS04160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK72_RS04180	COG1012	belongs to the aldehyde dehydrogenase family
RK72_RS04190	COG1510	regulation of RNA biosynthetic process
RK72_RS04195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK72_RS04220	COG2851	Citrate transporter
RK72_RS04235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RK72_RS04245	COG0386	Belongs to the glutathione peroxidase family
RK72_RS04270	COG1136	(ABC) transporter
RK72_RS04275	COG2205	protein histidine kinase activity
RK72_RS04280	COG0745	RESPONSE REGULATOR receiver
RK72_RS04290	COG1785	Belongs to the alkaline phosphatase family
RK72_RS04300	COG1846	Transcriptional regulator
RK72_RS04345	COG1438	arginine binding
RK72_RS04365	COG3711	transcriptional antiterminator
RK72_RS04365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK72_RS04370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK72_RS04370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK72_RS04370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK72_RS04375	COG1482	cell wall glycoprotein biosynthetic process
RK72_RS04385	COG3942	CHAP domain
RK72_RS04385	COG1705	Flagellar rod assembly protein muramidase FlgJ
RK72_RS04390	COG1535	isochorismatase
RK72_RS04390	COG3433	isochorismatase activity
RK72_RS04405	COG0438	transferase activity, transferring glycosyl groups
RK72_RS04420	COG1073	alpha beta
RK72_RS04440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK72_RS04460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK72_RS04555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RK72_RS04640	COG0471	metal ion transport
RK72_RS04645	COG2962	Rard protein
RK72_RS04655	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RK72_RS04670	COG1136	(ABC) transporter
RK72_RS04675	COG0577	efflux transmembrane transporter activity
RK72_RS04685	COG1278	Cold shock
RK72_RS04705	COG1475	DNA binding
RK72_RS04745	COG2501	S4 domain
RK72_RS04765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RK72_RS04795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RK72_RS04805	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RK72_RS04815	COG0305	Participates in initiation and elongation during chromosome replication
RK72_RS04850	COG4863	YycH protein
RK72_RS04860	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RK72_RS04865	COG0737	Belongs to the 5'-nucleotidase family
RK72_RS04900	COG0730	response to heat
RK72_RS04905	COG1937	Protein conserved in bacteria
RK72_RS04910	COG2210	Belongs to the sulfur carrier protein TusA family
RK72_RS04915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK72_RS04970	COG0823	Involved in the tonB-independent uptake of proteins
RK72_RS05005	COG1473	amidohydrolase
RK72_RS05015	COG1283	sodium-dependent phosphate transmembrane transporter activity
RK72_RS05020	COG4716	Myosin-crossreactive antigen
RK72_RS05025	COG0697	spore germination
RK72_RS05040	COG1620	l-lactate permease
RK72_RS05060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK72_RS05065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK72_RS05070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK72_RS05080	COG2423	ornithine cyclodeaminase activity
RK72_RS05085	COG4264	IucA IucC family
RK72_RS05090	COG2814	Major facilitator Superfamily
RK72_RS05095	COG4264	IucA IucC family
RK72_RS05100	COG4264	IucA IucC family
RK72_RS05110	COG0019	diaminopimelate decarboxylase activity
RK72_RS05115	COG1475	DNA binding
RK72_RS05140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK72_RS05145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK72_RS05150	COG0438	transferase activity, transferring glycosyl groups
RK72_RS05185	COG0813	purine-nucleoside phosphorylase activity
RK72_RS05190	COG2814	Major facilitator Superfamily
RK72_RS05210	COG3639	organic phosphonate transmembrane transporter activity
RK72_RS05230	COG0737	Belongs to the 5'-nucleotidase family
RK72_RS05245	COG1012	belongs to the aldehyde dehydrogenase family
RK72_RS05245	COG1454	alcohol dehydrogenase
RK72_RS05270	COG1086	Polysaccharide biosynthesis protein
RK72_RS05280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK72_RS05310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK72_RS05320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RK72_RS05325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK72_RS05335	COG2832	Protein of unknown function (DUF454)
RK72_RS05375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RK72_RS05380	COG1960	acyl-CoA dehydrogenase activity
RK72_RS05385	COG5609	conserved protein (DUF2294)
RK72_RS05435	COG1114	Component of the transport system for branched-chain amino acids
RK72_RS05440	COG1335	isochorismatase
RK72_RS05445	COG3961	Belongs to the TPP enzyme family
RK72_RS05475	COG1737	Transcriptional regulator
RK72_RS05500	COG1136	(ABC) transporter
RK72_RS05505	COG0577	efflux transmembrane transporter activity
RK72_RS05505	COG1136	(ABC) transporter
RK72_RS05525	COG1131	(ABC) transporter
RK72_RS05540	COG0601	transmembrane transport
RK72_RS05545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK72_RS05555	COG0405	Gamma-glutamyltransferase
RK72_RS05575	COG3842	ATPase activity
RK72_RS05585	COG1175	transmembrane transport
RK72_RS05590	COG3833	ABC-type maltose transport systems, permease component
RK72_RS05595	COG0673	inositol 2-dehydrogenase activity
RK72_RS05600	COG0673	inositol 2-dehydrogenase activity
RK72_RS05610	COG1755	Isoprenylcysteine carboxyl methyltransferase
RK72_RS05665	COG0183	Belongs to the thiolase family
RK72_RS05675	COG1960	acyl-CoA dehydrogenase activity
RK72_RS05680	COG0318	PFAM AMP-dependent synthetase and ligase
RK72_RS05695	COG0747	negative chemotaxis
RK72_RS05700	COG3189	MarR family transcriptional regulator
RK72_RS05735	COG1263	PTS System
RK72_RS05735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK72_RS05735	COG2190	(PTS) system
RK72_RS05740	COG1957	nucleoside hydrolase
RK72_RS05760	COG3414	Phosphotransferase system galactitol-specific IIB component
RK72_RS05765	COG3775	system Galactitol-specific IIC component
RK72_RS05770	COG1063	alcohol dehydrogenase
RK72_RS05780	COG1063	alcohol dehydrogenase
RK72_RS05790	COG1063	alcohol dehydrogenase
RK72_RS05795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK72_RS05800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK72_RS05810	COG1063	alcohol dehydrogenase
RK72_RS05815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK72_RS05850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK72_RS05860	COG1263	PTS System
RK72_RS05860	COG2190	(PTS) system
RK72_RS05860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK72_RS05865	COG2723	6-phospho-beta-galactosidase activity
RK72_RS05875	COG2226	methyltransferase
RK72_RS05930	COG1131	(ABC) transporter
RK72_RS05950	COG1388	LysM domain
RK72_RS05950	COG3942	CHAP domain
RK72_RS06070	COG1114	Component of the transport system for branched-chain amino acids
RK72_RS06080	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
RK72_RS06090	COG0577	efflux transmembrane transporter activity
RK72_RS06120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK72_RS06125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RK72_RS06150	COG3314	Sporulation integral membrane protein YlbJ
RK72_RS06175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK72_RS06205	COG3037	sugar-specific permease SgaT UlaA
RK72_RS06215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK72_RS06220	COG3711	transcriptional antiterminator
RK72_RS06245	COG2271	Major facilitator Superfamily
RK72_RS06250	COG0346	lactoylglutathione lyase activity
RK72_RS06255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK72_RS06260	COG0431	NADPH-dependent FMN reductase
RK72_RS06275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK72_RS06280	COG2822	iron ion transport
RK72_RS06295	COG0805	protein transport
RK72_RS06300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RK72_RS06310	COG1476	TRANSCRIPTIONal
RK72_RS06320	COG1131	(ABC) transporter
RK72_RS06350	COG0646	methionine synthase
RK72_RS06350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RK72_RS06355	COG0626	cystathionine gamma-synthase activity
RK72_RS06360	COG0626	cystathionine gamma-synthase activity
RK72_RS06370	COG1475	DNA binding
RK72_RS06375	COG0668	transmembrane transport
RK72_RS06380	COG4481	Protein conserved in bacteria
RK72_RS06385	COG0012	GTP binding
RK72_RS06490	COG1823	symporter activity
RK72_RS06525	COG2233	PERMEase
RK72_RS06565	COG3759	membrane
RK72_RS06725	COG0523	cobalamin synthesis protein
RK72_RS06750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RK72_RS06760	COG5609	conserved protein (DUF2294)
RK72_RS06775	COG1647	Serine aminopeptidase, S33
RK72_RS06780	COG0733	neurotransmitter:sodium symporter activity
RK72_RS06785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RK72_RS06790	COG0626	cystathionine gamma-synthase activity
RK72_RS06800	COG2011	ABC-type metal ion transport system permease component
RK72_RS06805	COG1464	Belongs to the NlpA lipoprotein family
RK72_RS06840	COG0583	DNA-binding transcription factor activity
RK72_RS06845	COG0067	glutamate synthase
RK72_RS06845	COG0069	glutamate synthase activity
RK72_RS06845	COG0070	glutamate synthase
RK72_RS06850	COG0493	'glutamate synthase
RK72_RS06860	COG1263	PTS System
RK72_RS06860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK72_RS06865	COG0366	Alpha amylase catalytic
RK72_RS06870	COG2188	Transcriptional regulator
RK72_RS06890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RK72_RS06930	COG1982	Orn Lys Arg decarboxylase major
RK72_RS06940	COG3870	Protein conserved in bacteria
RK72_RS06945	COG0470	DNA polymerase III
RK72_RS06950	COG1774	PSP1 C-terminal conserved region
RK72_RS06960	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RK72_RS06970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RK72_RS06980	COG0084	hydrolase, TatD family'
RK72_RS06985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK72_RS06995	COG4466	Protein conserved in bacteria
RK72_RS07005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RK72_RS07010	COG0251	oxidation-reduction process
RK72_RS07055	COG2244	polysaccharide biosynthetic process
RK72_RS07060	COG3956	TIGRFAM MazG family protein
RK72_RS07065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RK72_RS07075	COG1098	S1 RNA binding domain
RK72_RS07090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RK72_RS07115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RK72_RS07210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK72_RS07225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK72_RS07235	COG3880	PFAM UvrB UvrC protein
RK72_RS07250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RK72_RS07255	COG4956	integral membrane protein (PIN domain superfamily)
RK72_RS07280	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RK72_RS07340	COG2813	Specifically methylates the guanine in position
RK72_RS07380	COG1473	amidohydrolase
RK72_RS07410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RK72_RS07415	COG1428	Deoxynucleoside kinase
RK72_RS07420	COG1428	Deoxynucleoside kinase
RK72_RS07430	COG0561	phosphatase activity
RK72_RS07475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RK72_RS07490	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RK72_RS07590	COG0095	Lipoate-protein ligase
RK72_RS07595	COG0083	homoserine kinase activity
RK72_RS07615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK72_RS07650	COG0667	Aldo Keto reductase
RK72_RS07660	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK72_RS07670	COG1078	dGTPase activity
RK72_RS07710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK72_RS07715	COG4139	cobalamin transport
RK72_RS07765	COG4974	Belongs to the 'phage' integrase family
RK72_RS07820	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK72_RS07825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK72_RS07830	COG1121	(ABC) transporter
RK72_RS07835	COG1321	iron dependent repressor
RK72_RS07845	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RK72_RS07855	COG1682	transport, permease protein
RK72_RS07860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK72_RS07870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RK72_RS07875	COG1686	Belongs to the peptidase S11 family
RK72_RS07880	COG1132	(ABC) transporter
RK72_RS07885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK72_RS07895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RK72_RS07900	COG1120	ATPase activity
RK72_RS07905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK72_RS07910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK72_RS07915	COG2376	Dihydroxyacetone kinase
RK72_RS07925	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RK72_RS07935	COG3949	Membrane
RK72_RS07960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK72_RS07975	COG1136	(ABC) transporter
RK72_RS07980	COG0577	efflux transmembrane transporter activity
RK72_RS07985	COG1392	Phosphate transport regulator
RK72_RS07990	COG0306	phosphate transporter
RK72_RS07995	COG3942	CHAP domain
RK72_RS07995	COG1388	LysM domain
RK72_RS08005	COG4977	sequence-specific DNA binding
RK72_RS08005	COG1917	Cupin 2, conserved barrel domain protein
RK72_RS08035	COG0583	DNA-binding transcription factor activity
RK72_RS08040	COG2814	Major facilitator Superfamily
RK72_RS08045	COG2839	Protein conserved in bacteria
RK72_RS08075	COG1611	Belongs to the LOG family
RK72_RS08095	COG4988	ABC transporter
RK72_RS08100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RK72_RS08110	COG0523	cobalamin synthesis protein
RK72_RS08115	COG4989	oxidoreductase activity
RK72_RS08125	COG0471	metal ion transport
RK72_RS08130	COG0415	Belongs to the DNA photolyase family
RK72_RS08160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RK72_RS08165	COG1349	DNA-binding transcription factor activity
RK72_RS08170	COG1105	Belongs to the carbohydrate kinase PfkB family
RK72_RS08175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK72_RS08175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK72_RS08175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK72_RS08180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RK72_RS08185	COG1253	flavin adenine dinucleotide binding
RK72_RS08190	COG0656	L-ascorbic acid biosynthetic process
RK72_RS08195	COG0463	Glycosyl transferase, family 2
RK72_RS08230	COG0720	synthase
RK72_RS08240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RK72_RS08240	COG0512	Glutamine amidotransferase of anthranilate synthase
RK72_RS08245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK72_RS08275	COG0488	(ABC) transporter
RK72_RS08280	COG0514	ATP-dependent DNA helicase (RecQ)
RK72_RS08285	COG0517	IMP dehydrogenase activity
RK72_RS08285	COG1125	glycine betaine transport
RK72_RS08290	COG1174	glycine betaine transport
RK72_RS08325	COG3104	oligopeptide transport
RK72_RS08355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK72_RS08360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK72_RS08370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK72_RS08375	COG4605	iron ion homeostasis
RK72_RS08380	COG4604	ABC transporter, ATP-binding protein
RK72_RS08385	COG4607	ABC-type enterochelin transport system periplasmic component
RK72_RS08440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RK72_RS08445	COG1739	Uncharacterized protein family UPF0029
RK72_RS08455	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RK72_RS08460	COG1040	competence protein
RK72_RS08500	COG1388	LysM domain
RK72_RS08500	COG3942	CHAP domain
RK72_RS08560	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RK72_RS08630	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RK72_RS08635	COG1647	Serine aminopeptidase, S33
RK72_RS08640	COG0557	exoribonuclease II activity
RK72_RS08715	COG1278	Cold shock
RK72_RS08755	COG0406	alpha-ribazole phosphatase activity
RK72_RS08760	COG1279	arginine transmembrane transporter activity
RK72_RS08785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK72_RS08790	COG1393	Belongs to the ArsC family
RK72_RS08805	COG3878	Protein conserved in bacteria
RK72_RS08815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK72_RS08830	COG2011	ABC-type metal ion transport system permease component
RK72_RS08835	COG1464	Belongs to the NlpA lipoprotein family
RK72_RS08850	COG0396	ATPase activity
RK72_RS08855	COG0719	Fe-S assembly protein
RK72_RS08865	COG0822	iron-sulfur transferase activity
RK72_RS08890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RK72_RS08965	COG0305	Participates in initiation and elongation during chromosome replication
RK72_RS09175	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK72_RS09175	COG1388	LysM domain
RK72_RS09230	COG1253	flavin adenine dinucleotide binding
RK72_RS09245	COG1801	Protein of unknown function DUF72
RK72_RS09250	COG0730	response to heat
RK72_RS09265	COG4470	Protein conserved in bacteria
RK72_RS09285	COG2445	Protein of unknown function DUF86
RK72_RS09315	COG1696	Membrane protein involved in D-alanine export
RK72_RS09325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RK72_RS09330	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RK72_RS09335	COG4837	Protein of unknown function (DUF1462)
RK72_RS09340	COG1252	NADH dehydrogenase
RK72_RS09350	COG0316	Belongs to the HesB IscA family
RK72_RS09360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RK72_RS09365	COG2056	Na+-H+ antiporter family
RK72_RS09370	COG2050	protein possibly involved in aromatic compounds catabolism
RK72_RS09425	COG1098	S1 RNA binding domain
RK72_RS09430	COG1902	pentaerythritol trinitrate reductase activity
RK72_RS09445	COG0584	glycerophosphoryl diester phosphodiesterase
RK72_RS09465	COG0398	Pfam SNARE associated Golgi protein
RK72_RS09530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RK72_RS09545	COG1881	PFAM PEBP family protein
RK72_RS09575	COG0601	transmembrane transport
RK72_RS09580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK72_RS09585	COG0444	Belongs to the ABC transporter superfamily
RK72_RS09590	COG4608	Belongs to the ABC transporter superfamily
RK72_RS09595	COG4166	transmembrane transport
RK72_RS09600	COG0747	negative chemotaxis
RK72_RS09605	COG0444	Belongs to the ABC transporter superfamily
RK72_RS09610	COG4608	Belongs to the ABC transporter superfamily
RK72_RS09615	COG0601	transmembrane transport
RK72_RS09620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK72_RS09645	COG1164	Oligoendopeptidase f
RK72_RS09655	COG2346	COG2346, Truncated hemoglobins
RK72_RS09670	COG2357	RelA SpoT domain protein
RK72_RS09680	COG0564	pseudouridine synthase activity
RK72_RS09685	COG2239	Acts as a magnesium transporter
RK72_RS09690	COG0569	domain protein
RK72_RS09690	COG0475	glutathione-regulated potassium exporter activity
RK72_RS09700	COG0628	permease
RK72_RS09705	COG1115	amino acid carrier protein
RK72_RS09745	COG0861	Integral membrane protein TerC family
RK72_RS09755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK72_RS09760	COG0737	Belongs to the 5'-nucleotidase family
RK72_RS09775	COG4903	ComK protein
RK72_RS09790	COG4873	Protein conserved in bacteria
RK72_RS09845	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK72_RS09855	COG2314	TM2 domain
RK72_RS09860	COG0456	acetyltransferase
RK72_RS09865	COG1575	Belongs to the MenA family. Type 1 subfamily
RK72_RS09875	COG1169	isochorismate synthase
RK72_RS09885	COG2267	carboxylic ester hydrolase activity
RK72_RS09910	COG0436	Aminotransferase
RK72_RS09915	COG3594	Acyltransferase
RK72_RS09945	COG1316	TRANSCRIPTIONal
RK72_RS09990	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RK72_RS10005	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RK72_RS10045	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RK72_RS10050	COG4172	Belongs to the ABC transporter superfamily
RK72_RS10055	COG4721	ABC-type cobalt transport system, permease component
RK72_RS10080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RK72_RS10100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RK72_RS10105	COG1271	oxidase subunit
RK72_RS10110	COG1294	oxidase, subunit
RK72_RS10115	COG0569	domain protein
RK72_RS10180	COG1176	ABC-type spermidine putrescine transport system, permease component I
RK72_RS10185	COG1177	transmembrane transport
RK72_RS10190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RK72_RS10215	COG0483	inositol monophosphate 1-phosphatase activity
RK72_RS10225	COG1217	gtp-binding protein TYPA
RK72_RS10235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RK72_RS10245	COG0772	Belongs to the SEDS family
RK72_RS10280	COG3679	Belongs to the UPF0342 family
RK72_RS10300	COG0742	ribosomal rna small subunit methyltransferase
RK72_RS10360	COG4509	Sortase family
RK72_RS10375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RK72_RS10420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RK72_RS10420	COG1796	DNA polymerase
RK72_RS10445	COG2009	succinate dehydrogenase
RK72_RS10450	COG1053	succinate dehydrogenase
RK72_RS10455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RK72_RS10585	COG1288	antiporter activity
RK72_RS10620	COG1011	Hydrolase
RK72_RS10645	COG4839	cell division protein FtsL
RK72_RS10650	COG0768	penicillin binding
RK72_RS10665	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RK72_RS10670	COG0849	cell division
RK72_RS10685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RK72_RS10695	COG0762	integral membrane protein
RK72_RS10700	COG2302	S4 RNA-binding domain
RK72_RS10705	COG3599	regulation of cell shape
RK72_RS10715	COG2514	catechol 2,3-dioxygenase activity
RK72_RS10735	COG0564	pseudouridine synthase activity
RK72_RS10745	COG2233	PERMEase
RK72_RS10790	COG1293	RNA-binding protein homologous to eukaryotic snRNP
RK72_RS10805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RK72_RS10810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RK72_RS10820	COG2314	TM2 domain
RK72_RS10835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RK72_RS10835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RK72_RS10845	COG0631	protein serine/threonine phosphatase activity
RK72_RS10860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK72_RS10875	COG1302	Protein conserved in bacteria
RK72_RS10925	COG1196	nuclear chromosome segregation
RK72_RS10930	COG0552	protein localization to endoplasmic reticulum
RK72_RS10940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RK72_RS10995	COG2348	transferase activity, transferring amino-acyl groups
RK72_RS11000	COG0758	DNA mediated transformation
RK72_RS11100	COG0195	Participates in both transcription termination and antitermination
RK72_RS11105	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RK72_RS11130	COG0196	riboflavin kinase activity
RK72_RS11160	COG2188	Transcriptional regulator
RK72_RS11165	COG0612	Peptidase, M16
RK72_RS11170	COG0612	Peptidase, M16
RK72_RS11175	COG0300	oxidoreductase activity
RK72_RS11195	COG1546	Belongs to the CinA family
RK72_RS11195	COG1058	Belongs to the CinA family
RK72_RS11215	COG1692	metallophosphoesterase
RK72_RS11220	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RK72_RS11220	COG0674	pyruvate-flavodoxin oxidoreductase activity
RK72_RS11225	COG1013	pyruvate-flavodoxin oxidoreductase activity
RK72_RS11260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RK72_RS11265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RK72_RS11290	COG1923	regulation of RNA biosynthetic process
RK72_RS11300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RK72_RS11305	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RK72_RS11310	COG0789	Transcriptional regulator
RK72_RS11395	COG1131	(ABC) transporter
RK72_RS11410	COG2197	response regulator
RK72_RS11420	COG1525	nuclease
RK72_RS11435	COG0527	aspartate kinase activity
RK72_RS11440	COG0460	homoserine dehydrogenase
RK72_RS11445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RK72_RS11470	COG0833	amino acid
RK72_RS11500	COG2340	Cysteine-rich secretory protein family
RK72_RS11535	COG4846	Membrane protein involved in cytochrome C biogenesis
RK72_RS11555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK72_RS11570	COG0824	Thioesterase
RK72_RS11610	COG1115	amino acid carrier protein
RK72_RS11625	COG0628	permease
RK72_RS11650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RK72_RS11660	COG1363	Peptidase, m42
RK72_RS11665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK72_RS11670	COG0512	Glutamine amidotransferase of anthranilate synthase
RK72_RS11715	COG0561	phosphatase activity
RK72_RS11760	COG0704	Plays a role in the regulation of phosphate uptake
RK72_RS11770	COG0581	inorganic phosphate transmembrane transporter activity
RK72_RS11775	COG0573	inorganic phosphate transmembrane transporter activity
RK72_RS11795	COG0488	(ABC) transporter
RK72_RS11805	COG0527	aspartate kinase activity
RK72_RS11810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RK72_RS11885	COG4548	von Willebrand factor, type A
RK72_RS11890	COG0714	Associated with various cellular activities
RK72_RS11935	COG0671	phosphoesterase, PA-phosphatase related
RK72_RS12030	COG0531	amino acid
RK72_RS12045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK72_RS12050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RK72_RS12065	COG0116	Belongs to the methyltransferase superfamily
RK72_RS12105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RK72_RS12105	COG4499	WXG100 protein secretion system (Wss), protein YukC
RK72_RS12115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RK72_RS12120	COG3935	DnaD domain protein
RK72_RS12145	COG0438	transferase activity, transferring glycosyl groups
RK72_RS12150	COG1694	Mazg nucleotide pyrophosphohydrolase
RK72_RS12155	COG2738	Putative neutral zinc metallopeptidase
RK72_RS12160	COG4347	Protein of unknown function (DUF1405)
RK72_RS12200	COG0142	geranyltranstransferase activity
RK72_RS12265	COG0492	ferredoxin-NADP+ reductase activity
RK72_RS12280	COG0514	ATP-dependent DNA helicase (RecQ)
RK72_RS12290	COG1141	Ferredoxin
RK72_RS12335	COG0745	RESPONSE REGULATOR receiver
RK72_RS12340	COG1187	pseudouridine synthase activity
RK72_RS12365	COG0735	belongs to the Fur family
RK72_RS12370	COG0494	nUDIX hydrolase
RK72_RS12375	COG0667	Aldo Keto reductase
RK72_RS12385	COG4221	oxidoreductase activity
RK72_RS12400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RK72_RS12410	COG0366	Alpha amylase catalytic
RK72_RS12415	COG1609	Transcriptional regulator
RK72_RS12440	COG2195	Cleaves the N-terminal amino acid of tripeptides
RK72_RS12450	COG4129	membrane
RK72_RS12460	COG0508	dehydrogenase complex catalyzes the overall conversion of
RK72_RS12465	COG0022	dehydrogenase e1 component
RK72_RS12470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RK72_RS12475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK72_RS12480	COG0497	DNA recombination
RK72_RS12510	COG1302	Protein conserved in bacteria
RK72_RS12515	COG0439	Biotin carboxylase
RK72_RS12520	COG0511	ligase activity, forming carbon-carbon bonds
RK72_RS12530	COG0006	proline dipeptidase activity
RK72_RS12545	COG0095	Lipoate-protein ligase
RK72_RS12550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK72_RS12595	COG4537	Required for transformation and DNA binding
RK72_RS12600	COG1459	type II secretion system
RK72_RS12605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RK72_RS12610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK72_RS12615	COG0011	TIGRFAM Protein of
RK72_RS12620	COG1940	carbohydrate kinase activity
RK72_RS12625	COG4483	Protein conserved in bacteria
RK72_RS12635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RK72_RS12645	COG0768	penicillin binding
RK72_RS12660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK72_RS12665	COG1121	(ABC) transporter
RK72_RS12675	COG0513	Belongs to the DEAD box helicase family
RK72_RS12685	COG2384	SAM-dependent methyltransferase
RK72_RS12705	COG0517	IMP dehydrogenase activity
RK72_RS12725	COG0295	cytidine deaminase activity
RK72_RS12740	COG1702	phosphate starvation-inducible protein PhoH
RK72_RS12755	COG1030	water channel activity
RK72_RS12765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RK72_RS12770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RK72_RS12800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RK72_RS12815	COG1466	dna polymerase III delta subunit
RK72_RS12820	COG2333	competence protein COMEC
RK72_RS12820	COG0658	competence protein
RK72_RS12825	COG2131	deaminase
RK72_RS12830	COG2183	response to ionizing radiation
RK72_RS12835	COG2226	methyltransferase
RK72_RS12840	COG0799	negative regulation of ribosome biogenesis
RK72_RS12845	COG1713	HD superfamily hydrolase involved in NAD metabolism
RK72_RS12855	COG1534	Rna-binding protein
RK72_RS12865	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RK72_RS12870	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RK72_RS12895	COG3177	Filamentation induced by cAMP protein fic
RK72_RS12900	COG1914	H( )-stimulated, divalent metal cation uptake system
RK72_RS12910	COG0439	Biotin carboxylase
RK72_RS12915	COG0511	ligase activity, forming carbon-carbon bonds
RK72_RS12920	COG1984	allophanate hydrolase subunit 2
RK72_RS12925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RK72_RS12940	COG0826	peptidase U32
RK72_RS12945	COG0826	peptidase U32
RK72_RS12975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RK72_RS12990	COG1104	cysteine desulfurase activity
RK72_RS12995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK72_RS13005	COG3237	CsbD-like
RK72_RS13010	COG1959	2 iron, 2 sulfur cluster binding
RK72_RS13015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RK72_RS13020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RK72_RS13065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RK72_RS13065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RK72_RS13070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK72_RS13070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK72_RS13075	COG1862	Preprotein translocase
RK72_RS13115	COG2868	ribosomal protein
RK72_RS13160	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RK72_RS13170	COG0285	dihydrofolate synthase activity
RK72_RS13180	COG2818	Glycosylase
RK72_RS13215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK72_RS13250	COG4112	unkown
RK72_RS13275	COG0833	amino acid
RK72_RS13290	COG1484	DNA-dependent DNA replication
RK72_RS13320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK72_RS13320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK72_RS13330	COG5002	protein histidine kinase activity
RK72_RS13335	COG0745	RESPONSE REGULATOR receiver
RK72_RS13350	COG0372	Belongs to the citrate synthase family
RK72_RS13355	COG1113	amino acid transport
RK72_RS13380	COG0281	malic enzyme
RK72_RS13390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RK72_RS13395	COG4109	DRTGG domain
RK72_RS13435	COG0827	DNA restriction-modification system
RK72_RS13445	COG0730	response to heat
RK72_RS13455	COG1104	cysteine desulfurase activity
RK72_RS13470	COG1956	GAF domain-containing protein
RK72_RS13490	COG0584	glycerophosphoryl diester phosphodiesterase
RK72_RS13495	COG1764	response to oxidative stress
RK72_RS13500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RK72_RS13505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK72_RS13520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK72_RS13520	COG1263	PTS System
RK72_RS13525	COG0204	Acyl-transferase
RK72_RS13530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK72_RS13565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK72_RS13570	COG0454	-acetyltransferase
RK72_RS13590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RK72_RS13590	COG1605	Chorismate mutase
RK72_RS13615	COG1674	ftsk spoiiie
RK72_RS13620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RK72_RS13630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK72_RS13635	COG1363	Peptidase, m42
RK72_RS13645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK72_RS13655	COG0510	thiamine kinase activity
RK72_RS13675	COG1187	pseudouridine synthase activity
RK72_RS13680	COG2244	polysaccharide biosynthetic process
RK72_RS13685	COG2081	HI0933 family
RK72_RS13705	COG2814	Major facilitator Superfamily
RK72_RS13710	COG1242	4 iron, 4 sulfur cluster binding
RK72_RS13715	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RK72_RS13725	COG2267	carboxylic ester hydrolase activity
RK72_RS13755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK72_RS13755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK72_RS13775	COG4193	domain, Protein
RK72_RS13775	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK72_RS13775	COG3266	domain, Protein
RK72_RS13805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RK72_RS13830	COG0656	L-ascorbic acid biosynthetic process
RK72_RS13850	COG1506	peptidase
RK72_RS13855	COG2816	NAD+ diphosphatase activity
RK72_RS14115	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
RK72_RS14145	COG1131	(ABC) transporter
RK72_RS14150	COG0537	adenosine 5'-monophosphoramidase activity
RK72_RS14180	COG0420	3'-5' exonuclease activity
RK72_RS14210	COG2197	response regulator
RK72_RS14215	COG2203	Gaf domain
RK72_RS14215	COG4585	Histidine kinase
RK72_RS14220	COG0564	pseudouridine synthase activity
RK72_RS14250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RK72_RS14255	COG1126	abc transporter atp-binding protein
RK72_RS14260	COG0765	amino acid transport