locus-tag	class	description
X998_RS00015	COG2501	S4 domain
X998_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
X998_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
X998_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
X998_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
X998_RS00110	COG4863	YycH protein
X998_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
X998_RS00125	COG0737	Belongs to the 5'-nucleotidase family
X998_RS00155	COG0584	glycerophosphoryl diester phosphodiesterase
X998_RS00160	COG2030	dehydratase
X998_RS00230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
X998_RS00235	COG2210	Belongs to the sulfur carrier protein TusA family
X998_RS00240	COG1937	Protein conserved in bacteria
X998_RS00245	COG0730	response to heat
X998_RS00295	COG0730	response to heat
X998_RS00300	COG1937	Protein conserved in bacteria
X998_RS00305	COG2210	Belongs to the sulfur carrier protein TusA family
X998_RS00310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
X998_RS00345	COG0655	NAD(P)H dehydrogenase (quinone) activity
X998_RS00360	COG0583	DNA-binding transcription factor activity
X998_RS00380	COG0823	Involved in the tonB-independent uptake of proteins
X998_RS00410	COG1473	amidohydrolase
X998_RS00420	COG1283	sodium-dependent phosphate transmembrane transporter activity
X998_RS00425	COG4716	Myosin-crossreactive antigen
X998_RS00430	COG0697	spore germination
X998_RS00445	COG1620	l-lactate permease
X998_RS00460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
X998_RS00465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
X998_RS00470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
X998_RS00480	COG2423	ornithine cyclodeaminase activity
X998_RS00485	COG4264	IucA IucC family
X998_RS00490	COG2814	Major facilitator Superfamily
X998_RS00495	COG4264	IucA IucC family
X998_RS00500	COG4264	IucA IucC family
X998_RS00510	COG0019	diaminopimelate decarboxylase activity
X998_RS00515	COG1475	DNA binding
X998_RS00545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
X998_RS00550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
X998_RS00555	COG0438	transferase activity, transferring glycosyl groups
X998_RS00590	COG0813	purine-nucleoside phosphorylase activity
X998_RS00595	COG2814	Major facilitator Superfamily
X998_RS00615	COG3639	organic phosphonate transmembrane transporter activity
X998_RS00635	COG0737	Belongs to the 5'-nucleotidase family
X998_RS00665	COG1012	belongs to the aldehyde dehydrogenase family
X998_RS00665	COG1454	alcohol dehydrogenase
X998_RS00690	COG1086	Polysaccharide biosynthesis protein
X998_RS00700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
X998_RS00730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
X998_RS00740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
X998_RS00745	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
X998_RS00755	COG2832	Protein of unknown function (DUF454)
X998_RS00790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
X998_RS00795	COG1960	acyl-CoA dehydrogenase activity
X998_RS00800	COG5609	conserved protein (DUF2294)
X998_RS00850	COG1114	Component of the transport system for branched-chain amino acids
X998_RS00855	COG1335	isochorismatase
X998_RS00860	COG3961	Belongs to the TPP enzyme family
X998_RS00885	COG1737	Transcriptional regulator
X998_RS00920	COG0601	transmembrane transport
X998_RS00925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
X998_RS00935	COG0405	Gamma-glutamyltransferase
X998_RS00955	COG3842	ATPase activity
X998_RS00965	COG1175	transmembrane transport
X998_RS00970	COG3833	ABC-type maltose transport systems, permease component
X998_RS00975	COG0673	inositol 2-dehydrogenase activity
X998_RS00980	COG0673	inositol 2-dehydrogenase activity
X998_RS00990	COG1755	Isoprenylcysteine carboxyl methyltransferase
X998_RS01055	COG0183	Belongs to the thiolase family
X998_RS01065	COG1960	acyl-CoA dehydrogenase activity
X998_RS01070	COG0318	PFAM AMP-dependent synthetase and ligase
X998_RS01085	COG0747	negative chemotaxis
X998_RS01090	COG3189	MarR family transcriptional regulator
X998_RS01120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
X998_RS01120	COG2190	(PTS) system
X998_RS01120	COG1263	PTS System
X998_RS01125	COG1957	nucleoside hydrolase
X998_RS01145	COG3414	Phosphotransferase system galactitol-specific IIB component
X998_RS01150	COG3775	system Galactitol-specific IIC component
X998_RS01155	COG1063	alcohol dehydrogenase
X998_RS01165	COG1063	alcohol dehydrogenase
X998_RS01175	COG1063	alcohol dehydrogenase
X998_RS01180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
X998_RS01185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
X998_RS01195	COG1063	alcohol dehydrogenase
X998_RS01200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
X998_RS01235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
X998_RS01240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
X998_RS01240	COG1263	PTS System
X998_RS01240	COG2190	(PTS) system
X998_RS01245	COG2723	6-phospho-beta-galactosidase activity
X998_RS01255	COG2226	methyltransferase
X998_RS01315	COG1131	(ABC) transporter
X998_RS01345	COG1388	LysM domain
X998_RS01345	COG3942	CHAP domain
X998_RS01500	COG1114	Component of the transport system for branched-chain amino acids
X998_RS01505	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
X998_RS01515	COG0577	efflux transmembrane transporter activity
X998_RS01540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
X998_RS01545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
X998_RS01570	COG3314	Sporulation integral membrane protein YlbJ
X998_RS01580	COG0582	viral genome integration into host DNA
X998_RS01700	COG0305	Participates in initiation and elongation during chromosome replication
X998_RS01770	COG0756	dUTP diphosphatase activity
X998_RS01880	COG5280	Phage tail tape measure protein TP901
X998_RS01880	COG3953	SLT domain
X998_RS01930	COG1388	LysM domain
X998_RS01930	COG0860	N-Acetylmuramoyl-L-alanine amidase
X998_RS01960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
X998_RS01990	COG3037	sugar-specific permease SgaT UlaA
X998_RS02000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
X998_RS02005	COG3711	transcriptional antiterminator
X998_RS02025	COG2271	Major facilitator Superfamily
X998_RS02030	COG0346	lactoylglutathione lyase activity
X998_RS02035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
X998_RS02040	COG0431	NADPH-dependent FMN reductase
X998_RS02055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
X998_RS02060	COG2822	iron ion transport
X998_RS02070	COG0672	)-iron permease
X998_RS02075	COG0805	protein transport
X998_RS02080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
X998_RS02090	COG1476	TRANSCRIPTIONal
X998_RS02100	COG1131	(ABC) transporter
X998_RS02135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
X998_RS02135	COG0646	methionine synthase
X998_RS02140	COG0626	cystathionine gamma-synthase activity
X998_RS02145	COG0626	cystathionine gamma-synthase activity
X998_RS02150	COG1475	DNA binding
X998_RS02155	COG0668	transmembrane transport
X998_RS02160	COG4481	Protein conserved in bacteria
X998_RS02165	COG0012	GTP binding
X998_RS02250	COG3634	alkyl hydroperoxide reductase activity
X998_RS02265	COG1823	symporter activity
X998_RS02295	COG2233	PERMEase
X998_RS02330	COG3759	membrane
X998_RS02455	COG0523	cobalamin synthesis protein
X998_RS02465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
X998_RS02475	COG5609	conserved protein (DUF2294)
X998_RS02490	COG1647	Serine aminopeptidase, S33
X998_RS02500	COG0733	neurotransmitter:sodium symporter activity
X998_RS02505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
X998_RS02510	COG0626	cystathionine gamma-synthase activity
X998_RS02520	COG2011	ABC-type metal ion transport system permease component
X998_RS02525	COG1464	Belongs to the NlpA lipoprotein family
X998_RS02560	COG0583	DNA-binding transcription factor activity
X998_RS02565	COG0067	glutamate synthase
X998_RS02565	COG0069	glutamate synthase activity
X998_RS02565	COG0070	glutamate synthase
X998_RS02570	COG0493	'glutamate synthase
X998_RS02580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
X998_RS02580	COG1263	PTS System
X998_RS02585	COG0366	Alpha amylase catalytic
X998_RS02590	COG2188	Transcriptional regulator
X998_RS02605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
X998_RS02640	COG1982	Orn Lys Arg decarboxylase major
X998_RS02650	COG3870	Protein conserved in bacteria
X998_RS02660	COG0470	DNA polymerase III
X998_RS02665	COG1774	PSP1 C-terminal conserved region
X998_RS02675	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
X998_RS02685	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
X998_RS02700	COG0084	hydrolase, TatD family'
X998_RS02705	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
X998_RS02715	COG4466	Protein conserved in bacteria
X998_RS02725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
X998_RS02730	COG0251	oxidation-reduction process
X998_RS02775	COG2244	polysaccharide biosynthetic process
X998_RS02780	COG3956	TIGRFAM MazG family protein
X998_RS02785	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
X998_RS02795	COG1098	S1 RNA binding domain
X998_RS02810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
X998_RS02835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
X998_RS02895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
X998_RS02910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
X998_RS02920	COG3880	PFAM UvrB UvrC protein
X998_RS02940	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
X998_RS02945	COG4956	integral membrane protein (PIN domain superfamily)
X998_RS02965	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
X998_RS03015	COG2813	Specifically methylates the guanine in position
X998_RS03055	COG1473	amidohydrolase
X998_RS03085	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
X998_RS03090	COG1428	Deoxynucleoside kinase
X998_RS03095	COG1428	Deoxynucleoside kinase
X998_RS03105	COG0561	phosphatase activity
X998_RS03145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
X998_RS03160	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
X998_RS03250	COG0095	Lipoate-protein ligase
X998_RS03255	COG0083	homoserine kinase activity
X998_RS03275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
X998_RS03360	COG0667	Aldo Keto reductase
X998_RS03365	COG0655	NAD(P)H dehydrogenase (quinone) activity
X998_RS03375	COG1078	dGTPase activity
X998_RS03410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
X998_RS03415	COG4139	cobalamin transport
X998_RS03465	COG4974	Belongs to the 'phage' integrase family
X998_RS03510	COG0803	Belongs to the bacterial solute-binding protein 9 family
X998_RS03515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
X998_RS03520	COG1121	(ABC) transporter
X998_RS03525	COG1321	iron dependent repressor
X998_RS03535	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
X998_RS03545	COG1682	transport, permease protein
X998_RS03550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
X998_RS03555	COG1216	Glycosyl transferase, family 2
X998_RS03560	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
X998_RS03565	COG1686	Belongs to the peptidase S11 family
X998_RS03570	COG1132	(ABC) transporter
X998_RS03575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
X998_RS03585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
X998_RS03590	COG1120	ATPase activity
X998_RS03595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
X998_RS03600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
X998_RS03605	COG2376	Dihydroxyacetone kinase
X998_RS03615	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
X998_RS03625	COG3949	Membrane
X998_RS03650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
X998_RS03665	COG1136	(ABC) transporter
X998_RS03670	COG0577	efflux transmembrane transporter activity
X998_RS03675	COG1392	Phosphate transport regulator
X998_RS03680	COG0306	phosphate transporter
X998_RS03685	COG3942	CHAP domain
X998_RS03685	COG1388	LysM domain
X998_RS03695	COG4977	sequence-specific DNA binding
X998_RS03695	COG1917	Cupin 2, conserved barrel domain protein
X998_RS03725	COG0583	DNA-binding transcription factor activity
X998_RS03735	COG2814	Major facilitator Superfamily
X998_RS03740	COG2839	Protein conserved in bacteria
X998_RS03770	COG1611	Belongs to the LOG family
X998_RS03790	COG4988	ABC transporter
X998_RS03795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
X998_RS03805	COG0523	cobalamin synthesis protein
X998_RS03810	COG4989	oxidoreductase activity
X998_RS03820	COG0471	metal ion transport
X998_RS03825	COG0415	Belongs to the DNA photolyase family
X998_RS03855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
X998_RS03860	COG1349	DNA-binding transcription factor activity
X998_RS03865	COG1105	Belongs to the carbohydrate kinase PfkB family
X998_RS03880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
X998_RS03885	COG1253	flavin adenine dinucleotide binding
X998_RS03890	COG0656	L-ascorbic acid biosynthetic process
X998_RS03895	COG0463	Glycosyl transferase, family 2
X998_RS03930	COG0720	synthase
X998_RS03940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
X998_RS03940	COG0512	Glutamine amidotransferase of anthranilate synthase
X998_RS03945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
X998_RS03980	COG0488	(ABC) transporter
X998_RS03985	COG0514	ATP-dependent DNA helicase (RecQ)
X998_RS03990	COG0517	IMP dehydrogenase activity
X998_RS03990	COG1125	glycine betaine transport
X998_RS03995	COG1174	glycine betaine transport
X998_RS04025	COG3104	oligopeptide transport
X998_RS04045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
X998_RS04050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
X998_RS04065	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
X998_RS04070	COG4605	iron ion homeostasis
X998_RS04075	COG4604	ABC transporter, ATP-binding protein
X998_RS04080	COG4607	ABC-type enterochelin transport system periplasmic component
X998_RS04135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
X998_RS04140	COG1739	Uncharacterized protein family UPF0029
X998_RS04150	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
X998_RS04155	COG1040	competence protein
X998_RS04185	COG3942	CHAP domain
X998_RS04185	COG1388	LysM domain
X998_RS04245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
X998_RS04310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
X998_RS04315	COG1647	Serine aminopeptidase, S33
X998_RS04320	COG0557	exoribonuclease II activity
X998_RS04390	COG1278	Cold shock
X998_RS04430	COG0406	alpha-ribazole phosphatase activity
X998_RS04435	COG1279	arginine transmembrane transporter activity
X998_RS04460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
X998_RS04465	COG1393	Belongs to the ArsC family
X998_RS04480	COG3878	Protein conserved in bacteria
X998_RS04490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
X998_RS04505	COG2011	ABC-type metal ion transport system permease component
X998_RS04510	COG1464	Belongs to the NlpA lipoprotein family
X998_RS04515	COG0582	viral genome integration into host DNA
X998_RS04620	COG3728	DNA packaging
X998_RS04620	COG5484	DNA packaging
X998_RS04660	COG0396	ATPase activity
X998_RS04665	COG0719	Fe-S assembly protein
X998_RS04675	COG0822	iron-sulfur transferase activity
X998_RS04695	COG1253	flavin adenine dinucleotide binding
X998_RS04710	COG1801	Protein of unknown function DUF72
X998_RS04715	COG0730	response to heat
X998_RS04730	COG4470	Protein conserved in bacteria
X998_RS04740	COG2445	Protein of unknown function DUF86
X998_RS04770	COG1696	Membrane protein involved in D-alanine export
X998_RS04780	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
X998_RS04785	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
X998_RS04790	COG4837	Protein of unknown function (DUF1462)
X998_RS04795	COG1252	NADH dehydrogenase
X998_RS04805	COG0316	Belongs to the HesB IscA family
X998_RS04815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
X998_RS04820	COG2056	Na+-H+ antiporter family
X998_RS04825	COG2050	protein possibly involved in aromatic compounds catabolism
X998_RS04880	COG1098	S1 RNA binding domain
X998_RS04885	COG1902	pentaerythritol trinitrate reductase activity
X998_RS04905	COG0584	glycerophosphoryl diester phosphodiesterase
X998_RS04925	COG0398	Pfam SNARE associated Golgi protein
X998_RS05005	COG0561	phosphatase activity
X998_RS05030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
X998_RS05045	COG1881	PFAM PEBP family protein
X998_RS05075	COG0601	transmembrane transport
X998_RS05080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
X998_RS05085	COG0444	Belongs to the ABC transporter superfamily
X998_RS05090	COG4608	Belongs to the ABC transporter superfamily
X998_RS05095	COG4166	transmembrane transport
X998_RS05100	COG0747	negative chemotaxis
X998_RS05105	COG0444	Belongs to the ABC transporter superfamily
X998_RS05110	COG4608	Belongs to the ABC transporter superfamily
X998_RS05115	COG0601	transmembrane transport
X998_RS05120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
X998_RS05145	COG1164	Oligoendopeptidase f
X998_RS05155	COG2346	COG2346, Truncated hemoglobins
X998_RS05170	COG2357	RelA SpoT domain protein
X998_RS05180	COG0564	pseudouridine synthase activity
X998_RS05185	COG2239	Acts as a magnesium transporter
X998_RS05190	COG0475	glutathione-regulated potassium exporter activity
X998_RS05190	COG0569	domain protein
X998_RS05200	COG0628	permease
X998_RS05205	COG1115	amino acid carrier protein
X998_RS05245	COG0861	Integral membrane protein TerC family
X998_RS05255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
X998_RS05260	COG0737	Belongs to the 5'-nucleotidase family
X998_RS05275	COG4903	ComK protein
X998_RS05290	COG4873	Protein conserved in bacteria
X998_RS05345	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
X998_RS05355	COG2314	TM2 domain
X998_RS05360	COG0456	acetyltransferase
X998_RS05365	COG1575	Belongs to the MenA family. Type 1 subfamily
X998_RS05370	COG1169	isochorismate synthase
X998_RS05380	COG2267	carboxylic ester hydrolase activity
X998_RS05405	COG0436	Aminotransferase
X998_RS05410	COG3594	Acyltransferase
X998_RS05440	COG1316	TRANSCRIPTIONal
X998_RS05445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
X998_RS05485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
X998_RS05500	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
X998_RS05530	COG0138	bifunctional purine biosynthesis protein purh
X998_RS05540	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
X998_RS05545	COG4172	Belongs to the ABC transporter superfamily
X998_RS05550	COG4721	ABC-type cobalt transport system, permease component
X998_RS05570	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
X998_RS05595	COG1271	oxidase subunit
X998_RS05600	COG1294	oxidase, subunit
X998_RS05605	COG0569	domain protein
X998_RS05675	COG1176	ABC-type spermidine putrescine transport system, permease component I
X998_RS05680	COG1177	transmembrane transport
X998_RS05685	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
X998_RS05710	COG0483	inositol monophosphate 1-phosphatase activity
X998_RS05720	COG1217	gtp-binding protein TYPA
X998_RS05730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
X998_RS05740	COG0772	Belongs to the SEDS family
X998_RS05775	COG3679	Belongs to the UPF0342 family
X998_RS05795	COG0742	ribosomal rna small subunit methyltransferase
X998_RS05855	COG4509	Sortase family
X998_RS05870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
X998_RS05900	COG1796	DNA polymerase
X998_RS05900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
X998_RS05925	COG2009	succinate dehydrogenase
X998_RS05930	COG1053	succinate dehydrogenase
X998_RS05935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
X998_RS06065	COG1288	antiporter activity
X998_RS06100	COG1011	Hydrolase
X998_RS06125	COG4839	cell division protein FtsL
X998_RS06130	COG0768	penicillin binding
X998_RS06145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
X998_RS06150	COG0849	cell division
X998_RS06165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
X998_RS06175	COG0762	integral membrane protein
X998_RS06180	COG2302	S4 RNA-binding domain
X998_RS06185	COG3599	regulation of cell shape
X998_RS06195	COG2514	catechol 2,3-dioxygenase activity
X998_RS06210	COG0564	pseudouridine synthase activity
X998_RS06220	COG2233	PERMEase
X998_RS06265	COG1293	RNA-binding protein homologous to eukaryotic snRNP
X998_RS06280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
X998_RS06285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
X998_RS06295	COG2314	TM2 domain
X998_RS06310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
X998_RS06310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
X998_RS06320	COG0631	protein serine/threonine phosphatase activity
X998_RS06335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
X998_RS06350	COG1302	Protein conserved in bacteria
X998_RS06360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
X998_RS06400	COG1196	nuclear chromosome segregation
X998_RS06405	COG0552	protein localization to endoplasmic reticulum
X998_RS06415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
X998_RS06480	COG0758	DNA mediated transformation
X998_RS06575	COG0195	Participates in both transcription termination and antitermination
X998_RS06580	COG2740	Nucleic-acid-binding protein implicated in transcription termination
X998_RS06605	COG0196	riboflavin kinase activity
X998_RS06630	COG2188	Transcriptional regulator
X998_RS06635	COG0612	Peptidase, M16
X998_RS06640	COG0612	Peptidase, M16
X998_RS06645	COG0300	oxidoreductase activity
X998_RS06665	COG1546	Belongs to the CinA family
X998_RS06665	COG1058	Belongs to the CinA family
X998_RS06685	COG1692	metallophosphoesterase
X998_RS06690	COG0674	pyruvate-flavodoxin oxidoreductase activity
X998_RS06690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
X998_RS06695	COG1013	pyruvate-flavodoxin oxidoreductase activity
X998_RS06730	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
X998_RS06735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
X998_RS06760	COG1923	regulation of RNA biosynthetic process
X998_RS06770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
X998_RS06775	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
X998_RS06780	COG0789	Transcriptional regulator
X998_RS06900	COG1131	(ABC) transporter
X998_RS06915	COG2197	response regulator
X998_RS06925	COG1525	nuclease
X998_RS06940	COG0527	aspartate kinase activity
X998_RS06945	COG0460	homoserine dehydrogenase
X998_RS06950	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
X998_RS06975	COG0833	amino acid
X998_RS07005	COG2340	Cysteine-rich secretory protein family
X998_RS07040	COG4846	Membrane protein involved in cytochrome C biogenesis
X998_RS07060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
X998_RS07070	COG0824	Thioesterase
X998_RS07090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
X998_RS07100	COG1115	amino acid carrier protein
X998_RS07115	COG0628	permease
X998_RS07120	COG0392	lysyltransferase activity
X998_RS07120	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
X998_RS07140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
X998_RS07150	COG1363	Peptidase, m42
X998_RS07155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
X998_RS07160	COG0512	Glutamine amidotransferase of anthranilate synthase
X998_RS07200	COG0561	phosphatase activity
X998_RS07245	COG0704	Plays a role in the regulation of phosphate uptake
X998_RS07255	COG0581	inorganic phosphate transmembrane transporter activity
X998_RS07260	COG0573	inorganic phosphate transmembrane transporter activity
X998_RS07285	COG0488	(ABC) transporter
X998_RS07290	COG0527	aspartate kinase activity
X998_RS07295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
X998_RS07380	COG4548	von Willebrand factor, type A
X998_RS07385	COG0714	Associated with various cellular activities
X998_RS07425	COG0671	phosphoesterase, PA-phosphatase related
X998_RS07490	COG1413	lyase activity
X998_RS07505	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
X998_RS07535	COG0531	amino acid
X998_RS07550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
X998_RS07555	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
X998_RS07575	COG0116	Belongs to the methyltransferase superfamily
X998_RS07605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
X998_RS07605	COG4499	WXG100 protein secretion system (Wss), protein YukC
X998_RS07615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
X998_RS07620	COG3935	DnaD domain protein
X998_RS07645	COG0438	transferase activity, transferring glycosyl groups
X998_RS07650	COG1694	Mazg nucleotide pyrophosphohydrolase
X998_RS07655	COG2738	Putative neutral zinc metallopeptidase
X998_RS07660	COG4347	Protein of unknown function (DUF1405)
X998_RS07700	COG0142	geranyltranstransferase activity
X998_RS07765	COG0492	ferredoxin-NADP+ reductase activity
X998_RS07780	COG0514	ATP-dependent DNA helicase (RecQ)
X998_RS07790	COG1141	Ferredoxin
X998_RS07835	COG5002	protein histidine kinase activity
X998_RS07840	COG0745	RESPONSE REGULATOR receiver
X998_RS07845	COG1187	pseudouridine synthase activity
X998_RS07870	COG0735	belongs to the Fur family
X998_RS07875	COG0494	nUDIX hydrolase
X998_RS07880	COG0667	Aldo Keto reductase
X998_RS07890	COG4221	oxidoreductase activity
X998_RS07905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
X998_RS07915	COG0366	Alpha amylase catalytic
X998_RS07920	COG1609	Transcriptional regulator
X998_RS07940	COG2195	Cleaves the N-terminal amino acid of tripeptides
X998_RS07950	COG4129	membrane
X998_RS07960	COG0508	dehydrogenase complex catalyzes the overall conversion of
X998_RS07965	COG0022	dehydrogenase e1 component
X998_RS07970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
X998_RS07975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
X998_RS07980	COG0497	DNA recombination
X998_RS08010	COG1302	Protein conserved in bacteria
X998_RS08015	COG0439	Biotin carboxylase
X998_RS08020	COG0511	ligase activity, forming carbon-carbon bonds
X998_RS08025	COG2826	transposase and inactivated derivatives, IS30 family
X998_RS08055	COG1674	ftsk spoiiie
X998_RS08060	COG0433	COG0433 Predicted ATPase
X998_RS08080	COG2946	Replication initiation factor
X998_RS08105	COG0006	proline dipeptidase activity
X998_RS08120	COG0095	Lipoate-protein ligase
X998_RS08125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
X998_RS08170	COG4537	Required for transformation and DNA binding
X998_RS08175	COG1459	type II secretion system
X998_RS08180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
X998_RS08185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
X998_RS08190	COG0011	TIGRFAM Protein of
X998_RS08195	COG1940	carbohydrate kinase activity
X998_RS08200	COG4483	Protein conserved in bacteria
X998_RS08210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
X998_RS08220	COG0768	penicillin binding
X998_RS08235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
X998_RS08240	COG1121	(ABC) transporter
X998_RS08250	COG0513	Belongs to the DEAD box helicase family
X998_RS08260	COG2384	SAM-dependent methyltransferase
X998_RS08280	COG0517	IMP dehydrogenase activity
X998_RS08300	COG0295	cytidine deaminase activity
X998_RS08315	COG1702	phosphate starvation-inducible protein PhoH
X998_RS08330	COG1030	water channel activity
X998_RS08340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
X998_RS08345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
X998_RS08375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
X998_RS08395	COG1466	dna polymerase III delta subunit
X998_RS08400	COG0658	competence protein
X998_RS08400	COG2333	competence protein COMEC
X998_RS08405	COG2131	deaminase
X998_RS08415	COG2226	methyltransferase
X998_RS08420	COG0799	negative regulation of ribosome biogenesis
X998_RS08425	COG1713	HD superfamily hydrolase involved in NAD metabolism
X998_RS08435	COG1534	Rna-binding protein
X998_RS08445	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
X998_RS08450	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
X998_RS08475	COG3177	Filamentation induced by cAMP protein fic
X998_RS08480	COG1914	H( )-stimulated, divalent metal cation uptake system
X998_RS08490	COG0439	Biotin carboxylase
X998_RS08495	COG0511	ligase activity, forming carbon-carbon bonds
X998_RS08500	COG1984	allophanate hydrolase subunit 2
X998_RS08505	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
X998_RS08520	COG0826	peptidase U32
X998_RS08525	COG0826	peptidase U32
X998_RS08555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
X998_RS08570	COG1104	cysteine desulfurase activity
X998_RS08575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
X998_RS08590	COG1959	2 iron, 2 sulfur cluster binding
X998_RS08595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
X998_RS08600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
X998_RS08640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
X998_RS08640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
X998_RS08645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
X998_RS08645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
X998_RS08650	COG1862	Preprotein translocase
X998_RS08690	COG2868	ribosomal protein
X998_RS08730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
X998_RS08740	COG0285	dihydrofolate synthase activity
X998_RS08750	COG2818	Glycosylase
X998_RS08785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
X998_RS08820	COG4112	unkown
X998_RS08845	COG0833	amino acid
X998_RS08890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
X998_RS08890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
X998_RS08900	COG5002	protein histidine kinase activity
X998_RS08905	COG0745	RESPONSE REGULATOR receiver
X998_RS08920	COG0372	Belongs to the citrate synthase family
X998_RS08925	COG1113	amino acid transport
X998_RS08960	COG0281	malic enzyme
X998_RS08970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
X998_RS08975	COG4109	DRTGG domain
X998_RS09015	COG0827	DNA restriction-modification system
X998_RS09035	COG1104	cysteine desulfurase activity
X998_RS09050	COG1956	GAF domain-containing protein
X998_RS09065	COG0584	glycerophosphoryl diester phosphodiesterase
X998_RS09070	COG1764	response to oxidative stress
X998_RS09075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
X998_RS09080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
X998_RS09095	COG1263	PTS System
X998_RS09095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
X998_RS09100	COG0204	Acyl-transferase
X998_RS09105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
X998_RS09140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
X998_RS09145	COG0454	-acetyltransferase
X998_RS09165	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
X998_RS09165	COG1605	Chorismate mutase
X998_RS09190	COG1674	ftsk spoiiie
X998_RS09195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
X998_RS09205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
X998_RS09210	COG1363	Peptidase, m42
X998_RS09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
X998_RS09230	COG0510	thiamine kinase activity
X998_RS09250	COG1187	pseudouridine synthase activity
X998_RS09255	COG2244	polysaccharide biosynthetic process
X998_RS09260	COG2081	HI0933 family
X998_RS09280	COG2814	Major facilitator Superfamily
X998_RS09285	COG1242	4 iron, 4 sulfur cluster binding
X998_RS09290	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
X998_RS09310	COG2267	carboxylic ester hydrolase activity
X998_RS09340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
X998_RS09340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
X998_RS09365	COG5632	N-Acetylmuramoyl-L-alanine amidase
X998_RS09365	COG4193	domain, Protein
X998_RS09365	COG3266	domain, Protein
X998_RS09395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
X998_RS09425	COG0656	L-ascorbic acid biosynthetic process
X998_RS09450	COG1506	peptidase
X998_RS09620	COG1131	(ABC) transporter
X998_RS09730	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
X998_RS09760	COG1131	(ABC) transporter
X998_RS09765	COG0537	adenosine 5'-monophosphoramidase activity
X998_RS09795	COG0420	3'-5' exonuclease activity
X998_RS09820	COG2197	response regulator
X998_RS09825	COG4585	Histidine kinase
X998_RS09825	COG2203	Gaf domain
X998_RS09830	COG0564	pseudouridine synthase activity
X998_RS09865	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
X998_RS09870	COG1126	abc transporter atp-binding protein
X998_RS09875	COG0765	amino acid transport
X998_RS10045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
X998_RS10050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
X998_RS10060	COG4129	membrane
X998_RS10085	COG1988	membrane-bound metal-dependent
X998_RS10100	COG1134	teichoic acid transport
X998_RS10100	COG1388	LysM domain
X998_RS10130	COG0535	radical SAM domain protein
X998_RS10135	COG1607	acyl-coa hydrolase
X998_RS10140	COG2309	aminopeptidase activity
X998_RS10160	COG1295	ribonuclease BN
X998_RS10165	COG2197	response regulator
X998_RS10280	COG4851	CamS sex pheromone cAM373 precursor
X998_RS10290	COG0210	DNA helicase
X998_RS10300	COG4496	protein, YerC YecD
X998_RS10335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
X998_RS10345	COG0077	Prephenate dehydratase
X998_RS10355	COG0471	metal ion transport
X998_RS10365	COG1335	isochorismatase
X998_RS10380	COG1012	belongs to the aldehyde dehydrogenase family
X998_RS10430	COG1131	(ABC) transporter
X998_RS10445	COG1725	Transcriptional regulator
X998_RS10500	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
X998_RS10505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
X998_RS10510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
X998_RS10525	COG5484	DNA packaging
X998_RS10525	COG3728	DNA packaging
X998_RS10600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
X998_RS10605	COG1621	beta-fructofuranosidase activity
X998_RS10610	COG1609	Transcriptional regulator
X998_RS10615	COG0004	ammonium transporteR
X998_RS10620	COG0425	Belongs to the sulfur carrier protein TusA family
X998_RS10625	COG2391	methyltransferase activity
X998_RS10635	COG0488	(ABC) transporter
X998_RS10645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
X998_RS10655	COG0456	acetyltransferase
X998_RS10660	COG1214	PFAM Peptidase M22, glycoprotease
X998_RS10665	COG0802	atpase or kinase
X998_RS10680	COG0028	Belongs to the TPP enzyme family
X998_RS10755	COG2183	response to ionizing radiation
X998_RS10760	COG1191	sigma factor activity
X998_RS10770	COG1366	Belongs to the anti-sigma-factor antagonist family
X998_RS10775	COG2208	phosphoserine phosphatase activity
X998_RS10810	COG3428	Bacterial PH domain
X998_RS10840	COG2205	protein histidine kinase activity
X998_RS10845	COG0745	RESPONSE REGULATOR receiver
X998_RS10855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
X998_RS10865	COG0772	Belongs to the SEDS family
X998_RS10880	COG1937	Protein conserved in bacteria
X998_RS10890	COG1418	mRNA catabolic process
X998_RS10940	COG0629	single-stranded DNA binding
X998_RS11015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
X998_RS11040	COG0009	L-threonylcarbamoyladenylate synthase
X998_RS11045	COG2890	protein-(glutamine-N5) methyltransferase activity
X998_RS11065	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
X998_RS11105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
X998_RS11160	COG0813	purine-nucleoside phosphorylase activity
X998_RS11165	COG0783	Belongs to the Dps family
X998_RS11185	COG1482	cell wall glycoprotein biosynthetic process
X998_RS11190	COG0702	epimerase
X998_RS11195	COG0640	Transcriptional regulator
X998_RS11230	COG0561	phosphatase activity
X998_RS11235	COG1119	ATPase activity
X998_RS11250	COG3711	transcriptional antiterminator
X998_RS11280	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
X998_RS11345	COG0489	protein tyrosine kinase activity
X998_RS11350	COG2814	Major facilitator Superfamily
X998_RS11365	COG1272	protein, Hemolysin III
X998_RS11375	COG1988	membrane-bound metal-dependent
X998_RS11385	COG3314	Sporulation integral membrane protein YlbJ
X998_RS11390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
X998_RS11395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
X998_RS11400	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
X998_RS11410	COG3457	Alanine racemase
X998_RS11415	COG4264	IucA IucC family
X998_RS11420	COG2814	Major facilitator Superfamily
X998_RS11460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
X998_RS11470	COG2130	NADP-dependent
X998_RS11540	COG0656	L-ascorbic acid biosynthetic process
X998_RS11545	COG0789	Transcriptional regulator
X998_RS11555	COG5492	domain, Protein
X998_RS11575	COG3527	Alpha-acetolactate decarboxylase
X998_RS11580	COG0028	Belongs to the TPP enzyme family
X998_RS11600	COG0542	response to heat
X998_RS11690	COG0201	protein transport
X998_RS11805	COG2252	PERMEase
X998_RS11850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
X998_RS11920	COG1763	Mo-molybdopterin cofactor biosynthetic process
X998_RS11940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
X998_RS11945	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
X998_RS11950	COG4149	molybdate abc transporter
X998_RS11955	COG0725	ABC transporter, periplasmic molybdate-binding protein
X998_RS11970	COG1268	BioY protein
X998_RS11985	COG1960	acyl-CoA dehydrogenase activity
X998_RS11990	COG4413	Urea transporter
X998_RS12055	COG3942	CHAP domain
X998_RS12065	COG1757	Na H antiporter
X998_RS12080	COG3942	CHAP domain
X998_RS12155	COG1113	amino acid transport
X998_RS12175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
X998_RS12180	COG0385	Bile acid
X998_RS12190	COG1263	PTS System
X998_RS12190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
X998_RS12195	COG1737	Transcriptional regulator
X998_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
X998_RS12220	COG1473	amidohydrolase
X998_RS12235	COG0583	DNA-binding transcription factor activity
X998_RS12260	COG2258	MOSC domain
X998_RS12280	COG1668	transmembrane transport
X998_RS12285	COG4152	abc transporter atp-binding protein
X998_RS12290	COG3152	Membrane
X998_RS12300	COG0786	glutamate:sodium symporter activity
X998_RS12310	COG0598	Magnesium transport protein CorA
X998_RS12325	COG0657	acetylesterase activity
X998_RS12335	COG2814	Major facilitator Superfamily
X998_RS12340	COG1566	PFAM secretion protein HlyD family protein
X998_RS12350	COG2814	Major facilitator Superfamily
X998_RS12420	COG1620	l-lactate permease
X998_RS12440	COG0604	alcohol dehydrogenase
X998_RS12445	COG0456	acetyltransferase
X998_RS12470	COG1511	domain protein
X998_RS12485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
X998_RS12485	COG1263	PTS System
X998_RS12500	COG3871	stress protein (general stress protein 26)
X998_RS12545	COG0789	Transcriptional regulator
X998_RS12565	COG2181	nitrate reductase activity
X998_RS12575	COG1140	nitrate reductase beta subunit
X998_RS12580	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
X998_RS12590	COG2146	nitrite reductase [NAD(P)H] activity
X998_RS12595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
X998_RS12605	COG0454	-acetyltransferase
X998_RS12610	COG2116	formate transmembrane transporter activity
X998_RS12625	COG3443	Belongs to the bacterial solute-binding protein 9 family
X998_RS12625	COG0803	Belongs to the bacterial solute-binding protein 9 family
X998_RS12660	COG1126	abc transporter atp-binding protein
X998_RS12665	COG0765	amino acid transport
X998_RS12670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
X998_RS12675	COG2814	Major facilitator Superfamily
X998_RS12695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
X998_RS12740	COG0156	8-amino-7-oxononanoate synthase activity
X998_RS12750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
X998_RS12755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
X998_RS12770	COG1132	(ABC) transporter
X998_RS12775	COG2375	cellular response to nickel ion
X998_RS12775	COG1132	(ABC) transporter
X998_RS12795	COG1929	Belongs to the glycerate kinase type-1 family
X998_RS12805	COG2814	Major facilitator Superfamily
X998_RS12825	COG1113	amino acid transport
X998_RS12840	COG0531	amino acid
X998_RS12865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
X998_RS12875	COG1174	glycine betaine transport
X998_RS12885	COG1174	glycine betaine transport
X998_RS12905	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
X998_RS12910	COG0531	amino acid
X998_RS12915	COG2272	Belongs to the type-B carboxylesterase lipase family
X998_RS12920	COG2814	Major facilitator Superfamily
X998_RS12925	COG0390	transport system, permease component
X998_RS12930	COG4619	ABC transporter
X998_RS12935	COG1363	Peptidase, m42
X998_RS12955	COG4808	Protein conserved in bacteria
X998_RS12960	COG0069	glutamate synthase activity
X998_RS12975	COG1124	(ABC) transporter
X998_RS12980	COG0444	Belongs to the ABC transporter superfamily
X998_RS12985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
X998_RS12990	COG0601	transmembrane transport
X998_RS12995	COG0747	negative chemotaxis
X998_RS13025	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
X998_RS13030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
X998_RS13115	COG0494	nUDIX hydrolase
X998_RS13145	COG3583	domain protein
X998_RS13150	COG1846	Transcriptional regulator
X998_RS13185	COG1070	Carbohydrate kinase
X998_RS13190	COG1802	Transcriptional regulator
X998_RS13195	COG0789	Transcriptional regulator
X998_RS13200	COG2357	RelA SpoT domain protein
X998_RS13205	COG4876	unkown
X998_RS13215	COG2271	Major facilitator Superfamily
X998_RS13220	COG0586	Pfam SNARE associated Golgi protein
X998_RS13235	COG1846	Transcriptional regulator
X998_RS13240	COG1131	(ABC) transporter
X998_RS13260	COG3949	Membrane
X998_RS13265	COG0400	carboxylic ester hydrolase activity
X998_RS13270	COG0346	lactoylglutathione lyase activity
X998_RS13275	COG1846	Transcriptional regulator
X998_RS13285	COG2514	catechol 2,3-dioxygenase activity
X998_RS13300	COG0561	phosphatase activity
X998_RS13305	COG1131	(ABC) transporter
X998_RS13315	COG3764	Sortase (surface protein transpeptidase)
X998_RS13335	COG1760	l-serine dehydratase
X998_RS13340	COG1760	l-serine dehydratase
X998_RS13355	COG0697	spore germination
X998_RS13360	COG0657	acetylesterase activity
X998_RS13380	COG0028	Belongs to the TPP enzyme family
X998_RS13395	COG0583	DNA-binding transcription factor activity
X998_RS13405	COG3942	CHAP domain
X998_RS13430	COG3425	synthase
X998_RS13435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
X998_RS13440	COG0542	response to heat
X998_RS13460	COG2409	Drug exporters of the RND superfamily
X998_RS13505	COG0436	Aminotransferase
X998_RS13535	COG3942	CHAP domain
X998_RS13540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
X998_RS13540	COG2755	lipolytic protein G-D-S-L family
X998_RS13610	COG0596	Alpha beta hydrolase
X998_RS13645	COG3001	Fructosamine kinase
X998_RS13650	COG0167	dihydroorotate dehydrogenase activity
X998_RS13700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
X998_RS13705	COG3527	Alpha-acetolactate decarboxylase
X998_RS13720	COG0531	amino acid
X998_RS13750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
X998_RS13770	COG1012	belongs to the aldehyde dehydrogenase family
X998_RS13790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
X998_RS13815	COG2851	Citrate transporter
X998_RS13830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
X998_RS13840	COG0386	Belongs to the glutathione peroxidase family
X998_RS13865	COG1136	(ABC) transporter
X998_RS13870	COG2205	protein histidine kinase activity
X998_RS13875	COG0745	RESPONSE REGULATOR receiver
X998_RS13890	COG1785	Belongs to the alkaline phosphatase family
X998_RS13895	COG1846	Transcriptional regulator
X998_RS13940	COG1438	arginine binding
X998_RS13960	COG3711	transcriptional antiterminator
X998_RS13960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
X998_RS13965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
X998_RS13965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
X998_RS13965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
X998_RS13970	COG1482	cell wall glycoprotein biosynthetic process
X998_RS13980	COG1705	Flagellar rod assembly protein muramidase FlgJ
X998_RS13980	COG3942	CHAP domain
X998_RS13985	COG3433	isochorismatase activity
X998_RS13985	COG1535	isochorismatase
X998_RS14000	COG0438	transferase activity, transferring glycosyl groups
X998_RS14015	COG1073	alpha beta
X998_RS14035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
X998_RS14055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
X998_RS14110	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
X998_RS14145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
X998_RS14230	COG0471	metal ion transport
X998_RS14235	COG2962	Rard protein
X998_RS14245	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
X998_RS14260	COG1136	(ABC) transporter
X998_RS14265	COG0577	efflux transmembrane transporter activity
X998_RS14290	COG1278	Cold shock
X998_RS14310	COG1475	DNA binding