locus-tag	class	description
SaO267_RS00015	COG2501	S4 domain
SaO267_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaO267_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SaO267_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SaO267_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
SaO267_RS00120	COG4863	YycH protein
SaO267_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaO267_RS00135	COG0737	Belongs to the 5'-nucleotidase family
SaO267_RS00150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaO267_RS00195	COG1937	Protein conserved in bacteria
SaO267_RS00205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SaO267_RS00260	COG0823	Involved in the tonB-independent uptake of proteins
SaO267_RS00275	COG1473	amidohydrolase
SaO267_RS00285	COG1283	sodium-dependent phosphate transmembrane transporter activity
SaO267_RS00290	COG4716	Myosin-crossreactive antigen
SaO267_RS00300	COG1620	l-lactate permease
SaO267_RS00320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO267_RS00325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO267_RS00330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SaO267_RS00340	COG2423	ornithine cyclodeaminase activity
SaO267_RS00345	COG4264	IucA IucC family
SaO267_RS00350	COG2814	Major facilitator Superfamily
SaO267_RS00355	COG4264	IucA IucC family
SaO267_RS00360	COG4264	IucA IucC family
SaO267_RS00370	COG0019	diaminopimelate decarboxylase activity
SaO267_RS00375	COG1475	DNA binding
SaO267_RS00405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SaO267_RS00410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaO267_RS00415	COG0438	transferase activity, transferring glycosyl groups
SaO267_RS00445	COG0813	purine-nucleoside phosphorylase activity
SaO267_RS00450	COG2814	Major facilitator Superfamily
SaO267_RS00470	COG3639	organic phosphonate transmembrane transporter activity
SaO267_RS00490	COG0737	Belongs to the 5'-nucleotidase family
SaO267_RS00505	COG1012	belongs to the aldehyde dehydrogenase family
SaO267_RS00505	COG1454	alcohol dehydrogenase
SaO267_RS00530	COG1086	Polysaccharide biosynthesis protein
SaO267_RS00540	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SaO267_RS00570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaO267_RS00580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SaO267_RS00585	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SaO267_RS00595	COG2832	Protein of unknown function (DUF454)
SaO267_RS00630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SaO267_RS00635	COG1960	acyl-CoA dehydrogenase activity
SaO267_RS00660	COG3477	response to acidic pH
SaO267_RS00685	COG1114	Component of the transport system for branched-chain amino acids
SaO267_RS00690	COG1335	isochorismatase
SaO267_RS00695	COG3961	Belongs to the TPP enzyme family
SaO267_RS00725	COG1737	Transcriptional regulator
SaO267_RS00760	COG0601	transmembrane transport
SaO267_RS00765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaO267_RS00775	COG0405	Gamma-glutamyltransferase
SaO267_RS00790	COG3842	ATPase activity
SaO267_RS00800	COG1175	transmembrane transport
SaO267_RS00805	COG3833	ABC-type maltose transport systems, permease component
SaO267_RS00810	COG0673	inositol 2-dehydrogenase activity
SaO267_RS00815	COG0673	inositol 2-dehydrogenase activity
SaO267_RS00825	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaO267_RS00885	COG0183	Belongs to the thiolase family
SaO267_RS00895	COG1960	acyl-CoA dehydrogenase activity
SaO267_RS00900	COG0318	PFAM AMP-dependent synthetase and ligase
SaO267_RS00915	COG0747	negative chemotaxis
SaO267_RS00920	COG3189	MarR family transcriptional regulator
SaO267_RS00955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO267_RS00955	COG2190	(PTS) system
SaO267_RS00955	COG1263	PTS System
SaO267_RS00960	COG1957	nucleoside hydrolase
SaO267_RS00980	COG3414	Phosphotransferase system galactitol-specific IIB component
SaO267_RS00985	COG3775	system Galactitol-specific IIC component
SaO267_RS00990	COG1063	alcohol dehydrogenase
SaO267_RS01000	COG1063	alcohol dehydrogenase
SaO267_RS01010	COG1063	alcohol dehydrogenase
SaO267_RS01015	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SaO267_RS01020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SaO267_RS01030	COG1063	alcohol dehydrogenase
SaO267_RS01035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SaO267_RS01080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaO267_RS01090	COG1263	PTS System
SaO267_RS01090	COG2190	(PTS) system
SaO267_RS01090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO267_RS01095	COG2723	6-phospho-beta-galactosidase activity
SaO267_RS01110	COG2226	methyltransferase
SaO267_RS01160	COG1131	(ABC) transporter
SaO267_RS01190	COG3942	CHAP domain
SaO267_RS01190	COG1388	LysM domain
SaO267_RS01350	COG1114	Component of the transport system for branched-chain amino acids
SaO267_RS01360	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaO267_RS01370	COG0577	efflux transmembrane transporter activity
SaO267_RS01400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaO267_RS01405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SaO267_RS01430	COG3314	Sporulation integral membrane protein YlbJ
SaO267_RS01440	COG0582	viral genome integration into host DNA
SaO267_RS01540	COG0305	Participates in initiation and elongation during chromosome replication
SaO267_RS01910	COG1388	LysM domain
SaO267_RS01910	COG0860	N-Acetylmuramoyl-L-alanine amidase
SaO267_RS01945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SaO267_RS01970	COG3037	sugar-specific permease SgaT UlaA
SaO267_RS01980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaO267_RS01985	COG3711	transcriptional antiterminator
SaO267_RS02010	COG2271	Major facilitator Superfamily
SaO267_RS02015	COG0346	lactoylglutathione lyase activity
SaO267_RS02020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SaO267_RS02025	COG0431	NADPH-dependent FMN reductase
SaO267_RS02040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SaO267_RS02045	COG2822	iron ion transport
SaO267_RS02055	COG0672	)-iron permease
SaO267_RS02060	COG0805	protein transport
SaO267_RS02065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SaO267_RS02075	COG1476	TRANSCRIPTIONal
SaO267_RS02085	COG1131	(ABC) transporter
SaO267_RS02115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SaO267_RS02115	COG0646	methionine synthase
SaO267_RS02120	COG0626	cystathionine gamma-synthase activity
SaO267_RS02125	COG0626	cystathionine gamma-synthase activity
SaO267_RS02135	COG1475	DNA binding
SaO267_RS02140	COG0668	transmembrane transport
SaO267_RS02145	COG4481	Protein conserved in bacteria
SaO267_RS02150	COG0012	GTP binding
SaO267_RS02190	COG0582	viral genome integration into host DNA
SaO267_RS02260	COG1823	symporter activity
SaO267_RS02295	COG2233	PERMEase
SaO267_RS02310	COG0582	viral genome integration into host DNA
SaO267_RS02425	COG1683	Conserved Protein
SaO267_RS02435	COG3759	membrane
SaO267_RS02560	COG0523	cobalamin synthesis protein
SaO267_RS02585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SaO267_RS02595	COG5609	conserved protein (DUF2294)
SaO267_RS02610	COG1647	Serine aminopeptidase, S33
SaO267_RS02620	COG0733	neurotransmitter:sodium symporter activity
SaO267_RS02625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SaO267_RS02630	COG0626	cystathionine gamma-synthase activity
SaO267_RS02640	COG2011	ABC-type metal ion transport system permease component
SaO267_RS02645	COG1464	Belongs to the NlpA lipoprotein family
SaO267_RS02680	COG0583	DNA-binding transcription factor activity
SaO267_RS02685	COG0067	glutamate synthase
SaO267_RS02685	COG0069	glutamate synthase activity
SaO267_RS02685	COG0070	glutamate synthase
SaO267_RS02690	COG0493	'glutamate synthase
SaO267_RS02700	COG1263	PTS System
SaO267_RS02700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO267_RS02705	COG0366	Alpha amylase catalytic
SaO267_RS02710	COG2188	Transcriptional regulator
SaO267_RS02730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaO267_RS02760	COG1982	Orn Lys Arg decarboxylase major
SaO267_RS02770	COG3870	Protein conserved in bacteria
SaO267_RS02775	COG0470	DNA polymerase III
SaO267_RS02780	COG1774	PSP1 C-terminal conserved region
SaO267_RS02790	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaO267_RS02800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SaO267_RS02810	COG0084	hydrolase, TatD family'
SaO267_RS02815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SaO267_RS02825	COG4466	Protein conserved in bacteria
SaO267_RS02835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaO267_RS02840	COG0251	oxidation-reduction process
SaO267_RS02885	COG2244	polysaccharide biosynthetic process
SaO267_RS02890	COG3956	TIGRFAM MazG family protein
SaO267_RS02895	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaO267_RS02905	COG1098	S1 RNA binding domain
SaO267_RS02920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaO267_RS02950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SaO267_RS03025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaO267_RS03040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaO267_RS03050	COG3880	PFAM UvrB UvrC protein
SaO267_RS03065	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SaO267_RS03070	COG4956	integral membrane protein (PIN domain superfamily)
SaO267_RS03095	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaO267_RS03155	COG2813	Specifically methylates the guanine in position
SaO267_RS03195	COG1473	amidohydrolase
SaO267_RS03225	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaO267_RS03230	COG1428	Deoxynucleoside kinase
SaO267_RS03235	COG1428	Deoxynucleoside kinase
SaO267_RS03245	COG0561	phosphatase activity
SaO267_RS03290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SaO267_RS03410	COG0095	Lipoate-protein ligase
SaO267_RS03415	COG0083	homoserine kinase activity
SaO267_RS03435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaO267_RS03475	COG0667	Aldo Keto reductase
SaO267_RS03480	COG0655	NAD(P)H dehydrogenase (quinone) activity
SaO267_RS03490	COG1078	dGTPase activity
SaO267_RS03525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SaO267_RS03530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO267_RS03580	COG4974	Belongs to the 'phage' integrase family
SaO267_RS03625	COG0803	Belongs to the bacterial solute-binding protein 9 family
SaO267_RS03630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaO267_RS03635	COG1121	(ABC) transporter
SaO267_RS03640	COG1321	iron dependent repressor
SaO267_RS03650	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SaO267_RS03660	COG1682	transport, permease protein
SaO267_RS03665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SaO267_RS03675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SaO267_RS03680	COG1686	Belongs to the peptidase S11 family
SaO267_RS03685	COG1132	(ABC) transporter
SaO267_RS03690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaO267_RS03700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaO267_RS03705	COG1120	ATPase activity
SaO267_RS03710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO267_RS03715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO267_RS03720	COG2376	Dihydroxyacetone kinase
SaO267_RS03730	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaO267_RS03740	COG3949	Membrane
SaO267_RS03760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SaO267_RS03775	COG1136	(ABC) transporter
SaO267_RS03780	COG0577	efflux transmembrane transporter activity
SaO267_RS03785	COG1392	Phosphate transport regulator
SaO267_RS03790	COG0306	phosphate transporter
SaO267_RS03795	COG1388	LysM domain
SaO267_RS03795	COG3942	CHAP domain
SaO267_RS03805	COG4977	sequence-specific DNA binding
SaO267_RS03805	COG1917	Cupin 2, conserved barrel domain protein
SaO267_RS03835	COG0583	DNA-binding transcription factor activity
SaO267_RS03845	COG2839	Protein conserved in bacteria
SaO267_RS03875	COG1611	Belongs to the LOG family
SaO267_RS03895	COG4988	ABC transporter
SaO267_RS03900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaO267_RS03910	COG0523	cobalamin synthesis protein
SaO267_RS03915	COG4989	oxidoreductase activity
SaO267_RS03925	COG0471	metal ion transport
SaO267_RS03930	COG0415	Belongs to the DNA photolyase family
SaO267_RS03960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaO267_RS03965	COG1349	DNA-binding transcription factor activity
SaO267_RS03970	COG1105	Belongs to the carbohydrate kinase PfkB family
SaO267_RS03975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaO267_RS03975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaO267_RS03975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaO267_RS03980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SaO267_RS03985	COG1253	flavin adenine dinucleotide binding
SaO267_RS03990	COG0656	L-ascorbic acid biosynthetic process
SaO267_RS04030	COG0720	synthase
SaO267_RS04040	COG0512	Glutamine amidotransferase of anthranilate synthase
SaO267_RS04040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SaO267_RS04045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SaO267_RS04075	COG0488	(ABC) transporter
SaO267_RS04080	COG0514	ATP-dependent DNA helicase (RecQ)
SaO267_RS04085	COG0517	IMP dehydrogenase activity
SaO267_RS04085	COG1125	glycine betaine transport
SaO267_RS04090	COG1174	glycine betaine transport
SaO267_RS04120	COG3104	oligopeptide transport
SaO267_RS04150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaO267_RS04155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaO267_RS04165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO267_RS04170	COG4605	iron ion homeostasis
SaO267_RS04175	COG4604	ABC transporter, ATP-binding protein
SaO267_RS04180	COG4607	ABC-type enterochelin transport system periplasmic component
SaO267_RS04210	COG1929	Belongs to the glycerate kinase type-1 family
SaO267_RS04235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaO267_RS04240	COG1739	Uncharacterized protein family UPF0029
SaO267_RS04250	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SaO267_RS04255	COG1040	competence protein
SaO267_RS04285	COG3942	CHAP domain
SaO267_RS04285	COG1388	LysM domain
SaO267_RS04345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SaO267_RS04365	COG0281	malic enzyme
SaO267_RS04420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SaO267_RS04425	COG1647	Serine aminopeptidase, S33
SaO267_RS04430	COG0557	exoribonuclease II activity
SaO267_RS04490	COG1278	Cold shock
SaO267_RS04530	COG0406	alpha-ribazole phosphatase activity
SaO267_RS04535	COG1279	arginine transmembrane transporter activity
SaO267_RS04560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaO267_RS04565	COG1393	Belongs to the ArsC family
SaO267_RS04580	COG3878	Protein conserved in bacteria
SaO267_RS04585	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SaO267_RS04600	COG2011	ABC-type metal ion transport system permease component
SaO267_RS04605	COG1464	Belongs to the NlpA lipoprotein family
SaO267_RS04620	COG0396	ATPase activity
SaO267_RS04625	COG0719	Fe-S assembly protein
SaO267_RS04635	COG0822	iron-sulfur transferase activity
SaO267_RS04660	COG1253	flavin adenine dinucleotide binding
SaO267_RS04670	COG1801	Protein of unknown function DUF72
SaO267_RS04675	COG0730	response to heat
SaO267_RS04690	COG4470	Protein conserved in bacteria
SaO267_RS04700	COG2445	Protein of unknown function DUF86
SaO267_RS04730	COG1696	Membrane protein involved in D-alanine export
SaO267_RS04740	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SaO267_RS04745	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SaO267_RS04750	COG4837	Protein of unknown function (DUF1462)
SaO267_RS04755	COG1252	NADH dehydrogenase
SaO267_RS04765	COG0316	Belongs to the HesB IscA family
SaO267_RS04775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SaO267_RS04780	COG2056	Na+-H+ antiporter family
SaO267_RS04785	COG2050	protein possibly involved in aromatic compounds catabolism
SaO267_RS04840	COG1098	S1 RNA binding domain
SaO267_RS04845	COG1902	pentaerythritol trinitrate reductase activity
SaO267_RS04860	COG0584	glycerophosphoryl diester phosphodiesterase
SaO267_RS04885	COG0398	Pfam SNARE associated Golgi protein
SaO267_RS04925	COG0561	phosphatase activity
SaO267_RS04950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SaO267_RS04965	COG1881	PFAM PEBP family protein
SaO267_RS04995	COG0601	transmembrane transport
SaO267_RS05000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaO267_RS05005	COG0444	Belongs to the ABC transporter superfamily
SaO267_RS05010	COG4608	Belongs to the ABC transporter superfamily
SaO267_RS05015	COG4166	transmembrane transport
SaO267_RS05020	COG0747	negative chemotaxis
SaO267_RS05025	COG0444	Belongs to the ABC transporter superfamily
SaO267_RS05030	COG4608	Belongs to the ABC transporter superfamily
SaO267_RS05035	COG0601	transmembrane transport
SaO267_RS05040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaO267_RS05065	COG1164	Oligoendopeptidase f
SaO267_RS05075	COG2346	COG2346, Truncated hemoglobins
SaO267_RS05090	COG2357	RelA SpoT domain protein
SaO267_RS05100	COG0564	pseudouridine synthase activity
SaO267_RS05105	COG2239	Acts as a magnesium transporter
SaO267_RS05110	COG0569	domain protein
SaO267_RS05110	COG0475	glutathione-regulated potassium exporter activity
SaO267_RS05120	COG0628	permease
SaO267_RS05125	COG1115	amino acid carrier protein
SaO267_RS05165	COG0861	Integral membrane protein TerC family
SaO267_RS05175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaO267_RS05180	COG0737	Belongs to the 5'-nucleotidase family
SaO267_RS05195	COG4903	ComK protein
SaO267_RS05210	COG4873	Protein conserved in bacteria
SaO267_RS05260	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaO267_RS05270	COG2314	TM2 domain
SaO267_RS05280	COG1575	Belongs to the MenA family. Type 1 subfamily
SaO267_RS05290	COG1169	isochorismate synthase
SaO267_RS05300	COG2267	carboxylic ester hydrolase activity
SaO267_RS05325	COG0436	Aminotransferase
SaO267_RS05330	COG3594	Acyltransferase
SaO267_RS05360	COG1316	TRANSCRIPTIONal
SaO267_RS05405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaO267_RS05415	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaO267_RS05460	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SaO267_RS05465	COG4172	Belongs to the ABC transporter superfamily
SaO267_RS05470	COG4721	ABC-type cobalt transport system, permease component
SaO267_RS05490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SaO267_RS05510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaO267_RS05515	COG1271	oxidase subunit
SaO267_RS05520	COG1294	oxidase, subunit
SaO267_RS05525	COG0569	domain protein
SaO267_RS05590	COG1176	ABC-type spermidine putrescine transport system, permease component I
SaO267_RS05595	COG1177	transmembrane transport
SaO267_RS05600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SaO267_RS05625	COG0483	inositol monophosphate 1-phosphatase activity
SaO267_RS05635	COG1217	gtp-binding protein TYPA
SaO267_RS05645	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SaO267_RS05655	COG0772	Belongs to the SEDS family
SaO267_RS05690	COG3679	Belongs to the UPF0342 family
SaO267_RS05695	COG0584	glycerophosphoryl diester phosphodiesterase
SaO267_RS05710	COG0742	ribosomal rna small subunit methyltransferase
SaO267_RS05845	COG0305	Participates in initiation and elongation during chromosome replication
SaO267_RS06050	COG0739	heme binding
SaO267_RS06085	COG1388	LysM domain
SaO267_RS06085	COG5632	N-Acetylmuramoyl-L-alanine amidase
SaO267_RS06140	COG4509	Sortase family
SaO267_RS06155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaO267_RS06200	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SaO267_RS06200	COG1796	DNA polymerase
SaO267_RS06225	COG2009	succinate dehydrogenase
SaO267_RS06230	COG1053	succinate dehydrogenase
SaO267_RS06235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SaO267_RS06350	COG1288	antiporter activity
SaO267_RS06385	COG1011	Hydrolase
SaO267_RS06410	COG4839	cell division protein FtsL
SaO267_RS06415	COG0768	penicillin binding
SaO267_RS06430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SaO267_RS06435	COG0849	cell division
SaO267_RS06450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaO267_RS06460	COG0762	integral membrane protein
SaO267_RS06465	COG2302	S4 RNA-binding domain
SaO267_RS06470	COG3599	regulation of cell shape
SaO267_RS06480	COG2514	catechol 2,3-dioxygenase activity
SaO267_RS06500	COG0564	pseudouridine synthase activity
SaO267_RS06510	COG2233	PERMEase
SaO267_RS06555	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SaO267_RS06570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaO267_RS06575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaO267_RS06585	COG2314	TM2 domain
SaO267_RS06600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaO267_RS06600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaO267_RS06610	COG0631	protein serine/threonine phosphatase activity
SaO267_RS06625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SaO267_RS06640	COG1302	Protein conserved in bacteria
SaO267_RS06690	COG1196	nuclear chromosome segregation
SaO267_RS06695	COG0552	protein localization to endoplasmic reticulum
SaO267_RS06705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SaO267_RS06765	COG2348	transferase activity, transferring amino-acyl groups
SaO267_RS06770	COG0758	DNA mediated transformation
SaO267_RS06870	COG0195	Participates in both transcription termination and antitermination
SaO267_RS06875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaO267_RS06900	COG0196	riboflavin kinase activity
SaO267_RS06930	COG2188	Transcriptional regulator
SaO267_RS06935	COG0612	Peptidase, M16
SaO267_RS06940	COG0612	Peptidase, M16
SaO267_RS06945	COG0300	oxidoreductase activity
SaO267_RS06965	COG1546	Belongs to the CinA family
SaO267_RS06965	COG1058	Belongs to the CinA family
SaO267_RS06985	COG1692	metallophosphoesterase
SaO267_RS06990	COG0674	pyruvate-flavodoxin oxidoreductase activity
SaO267_RS06990	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SaO267_RS06995	COG1013	pyruvate-flavodoxin oxidoreductase activity
SaO267_RS07030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SaO267_RS07035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaO267_RS07060	COG1923	regulation of RNA biosynthetic process
SaO267_RS07070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SaO267_RS07075	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SaO267_RS07080	COG0789	Transcriptional regulator
SaO267_RS07180	COG1131	(ABC) transporter
SaO267_RS07195	COG2197	response regulator
SaO267_RS07205	COG1525	nuclease
SaO267_RS07220	COG0527	aspartate kinase activity
SaO267_RS07225	COG0460	homoserine dehydrogenase
SaO267_RS07230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SaO267_RS07255	COG0833	amino acid
SaO267_RS07285	COG2340	Cysteine-rich secretory protein family
SaO267_RS07320	COG4846	Membrane protein involved in cytochrome C biogenesis
SaO267_RS07340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaO267_RS07355	COG0824	Thioesterase
SaO267_RS07385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SaO267_RS07395	COG1115	amino acid carrier protein
SaO267_RS07410	COG0628	permease
SaO267_RS07435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SaO267_RS07445	COG1363	Peptidase, m42
SaO267_RS07450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SaO267_RS07455	COG0512	Glutamine amidotransferase of anthranilate synthase
SaO267_RS07545	COG0704	Plays a role in the regulation of phosphate uptake
SaO267_RS07555	COG0581	inorganic phosphate transmembrane transporter activity
SaO267_RS07560	COG0573	inorganic phosphate transmembrane transporter activity
SaO267_RS07575	COG0488	(ABC) transporter
SaO267_RS07585	COG0527	aspartate kinase activity
SaO267_RS07590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaO267_RS07625	COG2808	Putative FMN-binding domain
SaO267_RS07670	COG4548	von Willebrand factor, type A
SaO267_RS07675	COG0714	Associated with various cellular activities
SaO267_RS07720	COG0671	phosphoesterase, PA-phosphatase related
SaO267_RS07795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SaO267_RS07815	COG0531	amino acid
SaO267_RS07830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaO267_RS07835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SaO267_RS07850	COG0116	Belongs to the methyltransferase superfamily
SaO267_RS07890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaO267_RS07890	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaO267_RS07900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaO267_RS07905	COG3935	DnaD domain protein
SaO267_RS07930	COG0438	transferase activity, transferring glycosyl groups
SaO267_RS07935	COG1694	Mazg nucleotide pyrophosphohydrolase
SaO267_RS07940	COG2738	Putative neutral zinc metallopeptidase
SaO267_RS07980	COG0142	geranyltranstransferase activity
SaO267_RS08045	COG0492	ferredoxin-NADP+ reductase activity
SaO267_RS08060	COG0514	ATP-dependent DNA helicase (RecQ)
SaO267_RS08070	COG1141	Ferredoxin
SaO267_RS08090	COG5002	protein histidine kinase activity
SaO267_RS08095	COG0745	RESPONSE REGULATOR receiver
SaO267_RS08100	COG1187	pseudouridine synthase activity
SaO267_RS08125	COG0735	belongs to the Fur family
SaO267_RS08130	COG0494	nUDIX hydrolase
SaO267_RS08135	COG0667	Aldo Keto reductase
SaO267_RS08145	COG4221	oxidoreductase activity
SaO267_RS08160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SaO267_RS08170	COG0366	Alpha amylase catalytic
SaO267_RS08175	COG1609	Transcriptional regulator
SaO267_RS08195	COG2195	Cleaves the N-terminal amino acid of tripeptides
SaO267_RS08205	COG4129	membrane
SaO267_RS08215	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaO267_RS08220	COG0022	dehydrogenase e1 component
SaO267_RS08225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaO267_RS08230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaO267_RS08235	COG0497	DNA recombination
SaO267_RS08265	COG1302	Protein conserved in bacteria
SaO267_RS08270	COG0439	Biotin carboxylase
SaO267_RS08275	COG0511	ligase activity, forming carbon-carbon bonds
SaO267_RS08285	COG0006	proline dipeptidase activity
SaO267_RS08300	COG0095	Lipoate-protein ligase
SaO267_RS08305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SaO267_RS08350	COG4537	Required for transformation and DNA binding
SaO267_RS08355	COG1459	type II secretion system
SaO267_RS08360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaO267_RS08365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SaO267_RS08370	COG0011	TIGRFAM Protein of
SaO267_RS08375	COG1940	carbohydrate kinase activity
SaO267_RS08380	COG4483	Protein conserved in bacteria
SaO267_RS08390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaO267_RS08400	COG0768	penicillin binding
SaO267_RS08415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaO267_RS08420	COG1121	(ABC) transporter
SaO267_RS08430	COG0513	Belongs to the DEAD box helicase family
SaO267_RS08440	COG2384	SAM-dependent methyltransferase
SaO267_RS08460	COG0517	IMP dehydrogenase activity
SaO267_RS08480	COG0295	cytidine deaminase activity
SaO267_RS08495	COG1702	phosphate starvation-inducible protein PhoH
SaO267_RS08510	COG1030	water channel activity
SaO267_RS08520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SaO267_RS08525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaO267_RS08555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaO267_RS08575	COG1466	dna polymerase III delta subunit
SaO267_RS08580	COG0658	competence protein
SaO267_RS08580	COG2333	competence protein COMEC
SaO267_RS08585	COG2131	deaminase
SaO267_RS08595	COG2226	methyltransferase
SaO267_RS08600	COG0799	negative regulation of ribosome biogenesis
SaO267_RS08605	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaO267_RS08615	COG1534	Rna-binding protein
SaO267_RS08625	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaO267_RS08630	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SaO267_RS08650	COG3177	Filamentation induced by cAMP protein fic
SaO267_RS08655	COG1914	H( )-stimulated, divalent metal cation uptake system
SaO267_RS08665	COG0439	Biotin carboxylase
SaO267_RS08670	COG0511	ligase activity, forming carbon-carbon bonds
SaO267_RS08675	COG1984	allophanate hydrolase subunit 2
SaO267_RS08680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SaO267_RS08695	COG0826	peptidase U32
SaO267_RS08700	COG0826	peptidase U32
SaO267_RS08730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaO267_RS08745	COG1104	cysteine desulfurase activity
SaO267_RS08750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SaO267_RS08760	COG3237	CsbD-like
SaO267_RS08765	COG1959	2 iron, 2 sulfur cluster binding
SaO267_RS08770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaO267_RS08775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SaO267_RS08820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SaO267_RS08820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SaO267_RS08825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SaO267_RS08825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SaO267_RS08830	COG1862	Preprotein translocase
SaO267_RS08870	COG2868	ribosomal protein
SaO267_RS08915	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SaO267_RS08925	COG0285	dihydrofolate synthase activity
SaO267_RS08935	COG2818	Glycosylase
SaO267_RS08970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SaO267_RS09005	COG4112	unkown
SaO267_RS09030	COG0833	amino acid
SaO267_RS09045	COG1484	DNA-dependent DNA replication
SaO267_RS09075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaO267_RS09075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaO267_RS09085	COG5002	protein histidine kinase activity
SaO267_RS09090	COG0745	RESPONSE REGULATOR receiver
SaO267_RS09105	COG0372	Belongs to the citrate synthase family
SaO267_RS09110	COG1113	amino acid transport
SaO267_RS09135	COG0281	malic enzyme
SaO267_RS09145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaO267_RS09155	COG4109	DRTGG domain
SaO267_RS09200	COG0827	DNA restriction-modification system
SaO267_RS09210	COG0730	response to heat
SaO267_RS09220	COG1104	cysteine desulfurase activity
SaO267_RS09230	COG1956	GAF domain-containing protein
SaO267_RS09250	COG0584	glycerophosphoryl diester phosphodiesterase
SaO267_RS09255	COG1764	response to oxidative stress
SaO267_RS09260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SaO267_RS09265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SaO267_RS09280	COG1263	PTS System
SaO267_RS09280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO267_RS09285	COG0204	Acyl-transferase
SaO267_RS09290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SaO267_RS09325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SaO267_RS09330	COG0454	-acetyltransferase
SaO267_RS09350	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaO267_RS09350	COG1605	Chorismate mutase
SaO267_RS09375	COG1674	ftsk spoiiie
SaO267_RS09380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaO267_RS09390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaO267_RS09395	COG1363	Peptidase, m42
SaO267_RS09405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SaO267_RS09415	COG0510	thiamine kinase activity
SaO267_RS09435	COG1187	pseudouridine synthase activity
SaO267_RS09440	COG2244	polysaccharide biosynthetic process
SaO267_RS09445	COG2081	HI0933 family
SaO267_RS09465	COG2814	Major facilitator Superfamily
SaO267_RS09470	COG1242	4 iron, 4 sulfur cluster binding
SaO267_RS09475	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaO267_RS09485	COG2267	carboxylic ester hydrolase activity
SaO267_RS09515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SaO267_RS09515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SaO267_RS09540	COG3266	domain, Protein
SaO267_RS09540	COG5632	N-Acetylmuramoyl-L-alanine amidase
SaO267_RS09540	COG4193	domain, Protein
SaO267_RS09570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SaO267_RS09590	COG0656	L-ascorbic acid biosynthetic process
SaO267_RS09610	COG1506	peptidase
SaO267_RS09615	COG2816	NAD+ diphosphatase activity
SaO267_RS09665	COG1131	(ABC) transporter
SaO267_RS09780	COG1131	(ABC) transporter
SaO267_RS09920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SaO267_RS09940	COG0582	viral genome integration into host DNA
SaO267_RS09995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SaO267_RS10025	COG1131	(ABC) transporter
SaO267_RS10030	COG0537	adenosine 5'-monophosphoramidase activity
SaO267_RS10065	COG0420	3'-5' exonuclease activity
SaO267_RS10095	COG2197	response regulator
SaO267_RS10100	COG4585	Histidine kinase
SaO267_RS10100	COG2203	Gaf domain
SaO267_RS10105	COG0564	pseudouridine synthase activity
SaO267_RS10145	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaO267_RS10150	COG1126	abc transporter atp-binding protein
SaO267_RS10155	COG0765	amino acid transport
SaO267_RS10320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SaO267_RS10325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SaO267_RS10335	COG4129	membrane
SaO267_RS10355	COG1194	a g-specific adenine glycosylase
SaO267_RS10360	COG1988	membrane-bound metal-dependent
SaO267_RS10375	COG1134	teichoic acid transport
SaO267_RS10375	COG1388	LysM domain
SaO267_RS10470	COG5632	N-Acetylmuramoyl-L-alanine amidase
SaO267_RS10470	COG1388	LysM domain
SaO267_RS10515	COG0739	heme binding
SaO267_RS10570	COG4695	Portal protein
SaO267_RS10690	COG0305	Participates in initiation and elongation during chromosome replication
SaO267_RS10800	COG4974	Belongs to the 'phage' integrase family
SaO267_RS10805	COG0535	radical SAM domain protein
SaO267_RS10810	COG1607	acyl-coa hydrolase
SaO267_RS10815	COG2309	aminopeptidase activity
SaO267_RS10835	COG1295	ribonuclease BN
SaO267_RS10840	COG2197	response regulator
SaO267_RS10955	COG1733	regulation of RNA biosynthetic process
SaO267_RS10965	COG4851	CamS sex pheromone cAM373 precursor
SaO267_RS10985	COG4496	protein, YerC YecD
SaO267_RS11025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaO267_RS11035	COG0077	Prephenate dehydratase
SaO267_RS11055	COG1335	isochorismatase
SaO267_RS11070	COG1012	belongs to the aldehyde dehydrogenase family
SaO267_RS11120	COG1131	(ABC) transporter
SaO267_RS11135	COG1725	Transcriptional regulator
SaO267_RS11190	COG0156	8-amino-7-oxononanoate synthase activity
SaO267_RS11195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaO267_RS11295	COG0582	viral genome integration into host DNA
SaO267_RS11360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaO267_RS11365	COG1621	beta-fructofuranosidase activity
SaO267_RS11370	COG1609	Transcriptional regulator
SaO267_RS11375	COG0004	ammonium transporteR
SaO267_RS11380	COG0425	Belongs to the sulfur carrier protein TusA family
SaO267_RS11385	COG2391	methyltransferase activity
SaO267_RS11395	COG0488	(ABC) transporter
SaO267_RS11405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SaO267_RS11415	COG0456	acetyltransferase
SaO267_RS11420	COG1214	PFAM Peptidase M22, glycoprotease
SaO267_RS11425	COG0802	atpase or kinase
SaO267_RS11440	COG0028	Belongs to the TPP enzyme family
SaO267_RS11520	COG2183	response to ionizing radiation
SaO267_RS11525	COG1191	sigma factor activity
SaO267_RS11535	COG1366	Belongs to the anti-sigma-factor antagonist family
SaO267_RS11540	COG2208	phosphoserine phosphatase activity
SaO267_RS11575	COG3428	Bacterial PH domain
SaO267_RS11605	COG2205	protein histidine kinase activity
SaO267_RS11610	COG0745	RESPONSE REGULATOR receiver
SaO267_RS11620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaO267_RS11630	COG0772	Belongs to the SEDS family
SaO267_RS11645	COG1937	Protein conserved in bacteria
SaO267_RS11655	COG1418	mRNA catabolic process
SaO267_RS11700	COG0629	single-stranded DNA binding
SaO267_RS11770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SaO267_RS11795	COG0009	L-threonylcarbamoyladenylate synthase
SaO267_RS11800	COG2890	protein-(glutamine-N5) methyltransferase activity
SaO267_RS11825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SaO267_RS11865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SaO267_RS11915	COG0813	purine-nucleoside phosphorylase activity
SaO267_RS11920	COG0783	Belongs to the Dps family
SaO267_RS11940	COG1482	cell wall glycoprotein biosynthetic process
SaO267_RS11945	COG0702	epimerase
SaO267_RS11950	COG0640	Transcriptional regulator
SaO267_RS11980	COG0561	phosphatase activity
SaO267_RS11985	COG1119	ATPase activity
SaO267_RS12010	COG3711	transcriptional antiterminator
SaO267_RS12040	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaO267_RS12100	COG0489	protein tyrosine kinase activity
SaO267_RS12105	COG2814	Major facilitator Superfamily
SaO267_RS12125	COG1272	protein, Hemolysin III
SaO267_RS12135	COG1988	membrane-bound metal-dependent
SaO267_RS12145	COG3314	Sporulation integral membrane protein YlbJ
SaO267_RS12150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO267_RS12155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO267_RS12160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaO267_RS12170	COG3457	Alanine racemase
SaO267_RS12175	COG4264	IucA IucC family
SaO267_RS12180	COG2814	Major facilitator Superfamily
SaO267_RS12205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaO267_RS12215	COG2130	NADP-dependent
SaO267_RS12275	COG0656	L-ascorbic acid biosynthetic process
SaO267_RS12280	COG0789	Transcriptional regulator
SaO267_RS12290	COG5492	domain, Protein
SaO267_RS12310	COG3527	Alpha-acetolactate decarboxylase
SaO267_RS12315	COG0028	Belongs to the TPP enzyme family
SaO267_RS12405	COG0201	protein transport
SaO267_RS12520	COG2252	PERMEase
SaO267_RS12565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SaO267_RS12625	COG1763	Mo-molybdopterin cofactor biosynthetic process
SaO267_RS12645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SaO267_RS12650	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SaO267_RS12655	COG4149	molybdate abc transporter
SaO267_RS12660	COG0725	ABC transporter, periplasmic molybdate-binding protein
SaO267_RS12675	COG1268	BioY protein
SaO267_RS12695	COG1960	acyl-CoA dehydrogenase activity
SaO267_RS12700	COG4413	Urea transporter
SaO267_RS12765	COG3942	CHAP domain
SaO267_RS12775	COG1757	Na H antiporter
SaO267_RS12790	COG3942	CHAP domain
SaO267_RS12875	COG1113	amino acid transport
SaO267_RS12895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaO267_RS12900	COG0385	Bile acid
SaO267_RS12915	COG1737	Transcriptional regulator
SaO267_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
SaO267_RS12940	COG1473	amidohydrolase
SaO267_RS12955	COG0583	DNA-binding transcription factor activity
SaO267_RS12980	COG2258	MOSC domain
SaO267_RS13000	COG1668	transmembrane transport
SaO267_RS13005	COG4152	abc transporter atp-binding protein
SaO267_RS13010	COG3152	Membrane
SaO267_RS13025	COG0786	glutamate:sodium symporter activity
SaO267_RS13035	COG0598	Magnesium transport protein CorA
SaO267_RS13050	COG0657	acetylesterase activity
SaO267_RS13060	COG2814	Major facilitator Superfamily
SaO267_RS13065	COG1566	PFAM secretion protein HlyD family protein
SaO267_RS13075	COG2814	Major facilitator Superfamily
SaO267_RS13140	COG1131	(ABC) transporter
SaO267_RS13155	COG1620	l-lactate permease
SaO267_RS13175	COG0604	alcohol dehydrogenase
SaO267_RS13205	COG1511	domain protein
SaO267_RS13220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO267_RS13220	COG1263	PTS System
SaO267_RS13235	COG3871	stress protein (general stress protein 26)
SaO267_RS13280	COG0789	Transcriptional regulator
SaO267_RS13300	COG2181	nitrate reductase activity
SaO267_RS13310	COG1140	nitrate reductase beta subunit
SaO267_RS13315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SaO267_RS13325	COG2146	nitrite reductase [NAD(P)H] activity
SaO267_RS13330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SaO267_RS13340	COG0454	-acetyltransferase
SaO267_RS13345	COG2116	formate transmembrane transporter activity
SaO267_RS13360	COG0803	Belongs to the bacterial solute-binding protein 9 family
SaO267_RS13360	COG3443	Belongs to the bacterial solute-binding protein 9 family
SaO267_RS13395	COG1126	abc transporter atp-binding protein
SaO267_RS13400	COG0765	amino acid transport
SaO267_RS13405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaO267_RS13410	COG2814	Major facilitator Superfamily
SaO267_RS13425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaO267_RS13465	COG0156	8-amino-7-oxononanoate synthase activity
SaO267_RS13475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SaO267_RS13480	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SaO267_RS13495	COG1132	(ABC) transporter
SaO267_RS13500	COG1132	(ABC) transporter
SaO267_RS13500	COG2375	cellular response to nickel ion
SaO267_RS13520	COG1929	Belongs to the glycerate kinase type-1 family
SaO267_RS13530	COG2814	Major facilitator Superfamily
SaO267_RS13550	COG1113	amino acid transport
SaO267_RS13565	COG0531	amino acid
SaO267_RS13590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SaO267_RS13600	COG1174	glycine betaine transport
SaO267_RS13610	COG1174	glycine betaine transport
SaO267_RS13630	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SaO267_RS13635	COG0531	amino acid
SaO267_RS13640	COG2272	Belongs to the type-B carboxylesterase lipase family
SaO267_RS13645	COG2814	Major facilitator Superfamily
SaO267_RS13650	COG0390	transport system, permease component
SaO267_RS13655	COG4619	ABC transporter
SaO267_RS13660	COG1363	Peptidase, m42
SaO267_RS13680	COG4808	Protein conserved in bacteria
SaO267_RS13685	COG0069	glutamate synthase activity
SaO267_RS13700	COG1124	(ABC) transporter
SaO267_RS13710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaO267_RS13715	COG0601	transmembrane transport
SaO267_RS13720	COG0747	negative chemotaxis
SaO267_RS13745	COG1028	Short-chain dehydrogenase reductase Sdr
SaO267_RS13750	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SaO267_RS13755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SaO267_RS13815	COG0494	nUDIX hydrolase
SaO267_RS13880	COG1070	Carbohydrate kinase
SaO267_RS13885	COG1802	Transcriptional regulator
SaO267_RS13890	COG0789	Transcriptional regulator
SaO267_RS13895	COG2357	RelA SpoT domain protein
SaO267_RS13900	COG4876	unkown
SaO267_RS13915	COG2271	Major facilitator Superfamily
SaO267_RS13920	COG0586	Pfam SNARE associated Golgi protein
SaO267_RS13930	COG2814	Major facilitator Superfamily
SaO267_RS13935	COG1846	Transcriptional regulator
SaO267_RS13950	COG1131	(ABC) transporter
SaO267_RS13970	COG0400	carboxylic ester hydrolase activity
SaO267_RS13975	COG0346	lactoylglutathione lyase activity
SaO267_RS13980	COG1846	Transcriptional regulator
SaO267_RS13990	COG2514	catechol 2,3-dioxygenase activity
SaO267_RS14005	COG0561	phosphatase activity
SaO267_RS14010	COG1131	(ABC) transporter
SaO267_RS14020	COG3764	Sortase (surface protein transpeptidase)
SaO267_RS14040	COG1760	l-serine dehydratase
SaO267_RS14045	COG1760	l-serine dehydratase
SaO267_RS14060	COG0697	spore germination
SaO267_RS14065	COG0657	acetylesterase activity
SaO267_RS14090	COG0028	Belongs to the TPP enzyme family
SaO267_RS14105	COG0583	DNA-binding transcription factor activity
SaO267_RS14115	COG3942	CHAP domain
SaO267_RS14125	COG3425	synthase
SaO267_RS14130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaO267_RS14155	COG2409	Drug exporters of the RND superfamily
SaO267_RS14200	COG0436	Aminotransferase
SaO267_RS14340	COG3001	Fructosamine kinase
SaO267_RS14345	COG0167	dihydroorotate dehydrogenase activity
SaO267_RS14395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SaO267_RS14400	COG3527	Alpha-acetolactate decarboxylase
SaO267_RS14415	COG0531	amino acid
SaO267_RS14445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SaO267_RS14465	COG1012	belongs to the aldehyde dehydrogenase family
SaO267_RS14475	COG1510	regulation of RNA biosynthetic process
SaO267_RS14480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaO267_RS14505	COG2851	Citrate transporter
SaO267_RS14515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SaO267_RS14525	COG0386	Belongs to the glutathione peroxidase family
SaO267_RS14550	COG1136	(ABC) transporter
SaO267_RS14555	COG2205	protein histidine kinase activity
SaO267_RS14560	COG0745	RESPONSE REGULATOR receiver
SaO267_RS14570	COG1785	Belongs to the alkaline phosphatase family
SaO267_RS14580	COG1846	Transcriptional regulator
SaO267_RS14625	COG1438	arginine binding
SaO267_RS14645	COG3711	transcriptional antiterminator
SaO267_RS14645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaO267_RS14650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaO267_RS14650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaO267_RS14650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaO267_RS14655	COG1482	cell wall glycoprotein biosynthetic process
SaO267_RS14665	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaO267_RS14665	COG3942	CHAP domain
SaO267_RS14675	COG1535	isochorismatase
SaO267_RS14675	COG3433	isochorismatase activity
SaO267_RS14690	COG0438	transferase activity, transferring glycosyl groups
SaO267_RS14705	COG1073	alpha beta
SaO267_RS14725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SaO267_RS14765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SaO267_RS14855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SaO267_RS14910	COG0471	metal ion transport
SaO267_RS14915	COG2962	Rard protein
SaO267_RS14925	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SaO267_RS14940	COG1136	(ABC) transporter
SaO267_RS14945	COG0577	efflux transmembrane transporter activity
SaO267_RS14955	COG1278	Cold shock
SaO267_RS14980	COG1475	DNA binding