locus-tag	class	description
SaO55_RS00015	COG2501	S4 domain
SaO55_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaO55_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SaO55_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SaO55_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
SaO55_RS00120	COG4863	YycH protein
SaO55_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaO55_RS00135	COG0737	Belongs to the 5'-nucleotidase family
SaO55_RS00155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SaO55_RS00165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SaO55_RS00185	COG0730	response to heat
SaO55_RS00190	COG1937	Protein conserved in bacteria
SaO55_RS00195	COG2210	Belongs to the sulfur carrier protein TusA family
SaO55_RS00200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SaO55_RS00240	COG0655	NAD(P)H dehydrogenase (quinone) activity
SaO55_RS00255	COG0823	Involved in the tonB-independent uptake of proteins
SaO55_RS00270	COG1473	amidohydrolase
SaO55_RS00280	COG1283	sodium-dependent phosphate transmembrane transporter activity
SaO55_RS00285	COG4716	Myosin-crossreactive antigen
SaO55_RS00290	COG0697	spore germination
SaO55_RS00305	COG1620	l-lactate permease
SaO55_RS00325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO55_RS00330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO55_RS00335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SaO55_RS00345	COG2423	ornithine cyclodeaminase activity
SaO55_RS00350	COG4264	IucA IucC family
SaO55_RS00355	COG2814	Major facilitator Superfamily
SaO55_RS00360	COG4264	IucA IucC family
SaO55_RS00365	COG4264	IucA IucC family
SaO55_RS00375	COG0019	diaminopimelate decarboxylase activity
SaO55_RS00380	COG1475	DNA binding
SaO55_RS00410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SaO55_RS00415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaO55_RS00420	COG0438	transferase activity, transferring glycosyl groups
SaO55_RS00450	COG0813	purine-nucleoside phosphorylase activity
SaO55_RS00455	COG2814	Major facilitator Superfamily
SaO55_RS00475	COG3639	organic phosphonate transmembrane transporter activity
SaO55_RS00495	COG0737	Belongs to the 5'-nucleotidase family
SaO55_RS00510	COG1012	belongs to the aldehyde dehydrogenase family
SaO55_RS00510	COG1454	alcohol dehydrogenase
SaO55_RS00535	COG1086	Polysaccharide biosynthesis protein
SaO55_RS00545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SaO55_RS00575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaO55_RS00585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SaO55_RS00590	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SaO55_RS00600	COG2832	Protein of unknown function (DUF454)
SaO55_RS00635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SaO55_RS00670	COG3477	response to acidic pH
SaO55_RS00695	COG1114	Component of the transport system for branched-chain amino acids
SaO55_RS00700	COG1335	isochorismatase
SaO55_RS00705	COG3961	Belongs to the TPP enzyme family
SaO55_RS00735	COG1737	Transcriptional regulator
SaO55_RS00770	COG0601	transmembrane transport
SaO55_RS00775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaO55_RS00785	COG0405	Gamma-glutamyltransferase
SaO55_RS00800	COG3842	ATPase activity
SaO55_RS00810	COG1175	transmembrane transport
SaO55_RS00815	COG3833	ABC-type maltose transport systems, permease component
SaO55_RS00825	COG0673	inositol 2-dehydrogenase activity
SaO55_RS00830	COG0673	inositol 2-dehydrogenase activity
SaO55_RS00840	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaO55_RS00900	COG0183	Belongs to the thiolase family
SaO55_RS00910	COG1960	acyl-CoA dehydrogenase activity
SaO55_RS00915	COG0318	PFAM AMP-dependent synthetase and ligase
SaO55_RS00930	COG0747	negative chemotaxis
SaO55_RS00935	COG3189	MarR family transcriptional regulator
SaO55_RS00970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO55_RS00970	COG2190	(PTS) system
SaO55_RS00970	COG1263	PTS System
SaO55_RS00975	COG1957	nucleoside hydrolase
SaO55_RS00995	COG3414	Phosphotransferase system galactitol-specific IIB component
SaO55_RS01000	COG3775	system Galactitol-specific IIC component
SaO55_RS01005	COG1063	alcohol dehydrogenase
SaO55_RS01015	COG1063	alcohol dehydrogenase
SaO55_RS01025	COG1063	alcohol dehydrogenase
SaO55_RS01030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SaO55_RS01035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SaO55_RS01045	COG1063	alcohol dehydrogenase
SaO55_RS01050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SaO55_RS01090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaO55_RS01100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO55_RS01100	COG2190	(PTS) system
SaO55_RS01100	COG1263	PTS System
SaO55_RS01105	COG2723	6-phospho-beta-galactosidase activity
SaO55_RS01120	COG2226	methyltransferase
SaO55_RS01170	COG1131	(ABC) transporter
SaO55_RS01190	COG1388	LysM domain
SaO55_RS01190	COG3942	CHAP domain
SaO55_RS01305	COG1114	Component of the transport system for branched-chain amino acids
SaO55_RS01315	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaO55_RS01325	COG0577	efflux transmembrane transporter activity
SaO55_RS01355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaO55_RS01360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SaO55_RS01385	COG3314	Sporulation integral membrane protein YlbJ
SaO55_RS01405	COG0582	viral genome integration into host DNA
SaO55_RS01650	COG5280	Phage tail tape measure protein TP901
SaO55_RS01650	COG3953	SLT domain
SaO55_RS01710	COG1388	LysM domain
SaO55_RS01710	COG0860	N-Acetylmuramoyl-L-alanine amidase
SaO55_RS01745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SaO55_RS01770	COG3037	sugar-specific permease SgaT UlaA
SaO55_RS01780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaO55_RS01785	COG3711	transcriptional antiterminator
SaO55_RS01810	COG2271	Major facilitator Superfamily
SaO55_RS01820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SaO55_RS01825	COG0431	NADPH-dependent FMN reductase
SaO55_RS01835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SaO55_RS01840	COG2822	iron ion transport
SaO55_RS01850	COG0672	)-iron permease
SaO55_RS01860	COG0805	protein transport
SaO55_RS01865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SaO55_RS01875	COG1476	TRANSCRIPTIONal
SaO55_RS01885	COG1131	(ABC) transporter
SaO55_RS01915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SaO55_RS01915	COG0646	methionine synthase
SaO55_RS01920	COG0626	cystathionine gamma-synthase activity
SaO55_RS01925	COG0626	cystathionine gamma-synthase activity
SaO55_RS01935	COG1475	DNA binding
SaO55_RS01940	COG0668	transmembrane transport
SaO55_RS01945	COG4481	Protein conserved in bacteria
SaO55_RS01950	COG0012	GTP binding
SaO55_RS01985	COG4974	Belongs to the 'phage' integrase family
SaO55_RS01990	COG0582	viral genome integration into host DNA
SaO55_RS02065	COG1823	symporter activity
SaO55_RS02100	COG2233	PERMEase
SaO55_RS02115	COG0582	viral genome integration into host DNA
SaO55_RS02230	COG1683	Conserved Protein
SaO55_RS02235	COG3759	membrane
SaO55_RS02385	COG0523	cobalamin synthesis protein
SaO55_RS02410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SaO55_RS02420	COG5609	conserved protein (DUF2294)
SaO55_RS02435	COG1647	Serine aminopeptidase, S33
SaO55_RS02440	COG0733	neurotransmitter:sodium symporter activity
SaO55_RS02445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SaO55_RS02450	COG0626	cystathionine gamma-synthase activity
SaO55_RS02460	COG2011	ABC-type metal ion transport system permease component
SaO55_RS02465	COG1464	Belongs to the NlpA lipoprotein family
SaO55_RS02500	COG0583	DNA-binding transcription factor activity
SaO55_RS02505	COG0070	glutamate synthase
SaO55_RS02505	COG0067	glutamate synthase
SaO55_RS02505	COG0069	glutamate synthase activity
SaO55_RS02510	COG0493	'glutamate synthase
SaO55_RS02520	COG1263	PTS System
SaO55_RS02520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO55_RS02525	COG0366	Alpha amylase catalytic
SaO55_RS02530	COG2188	Transcriptional regulator
SaO55_RS02550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaO55_RS02590	COG1982	Orn Lys Arg decarboxylase major
SaO55_RS02600	COG3870	Protein conserved in bacteria
SaO55_RS02605	COG0470	DNA polymerase III
SaO55_RS02610	COG1774	PSP1 C-terminal conserved region
SaO55_RS02620	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaO55_RS02630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SaO55_RS02640	COG0084	hydrolase, TatD family'
SaO55_RS02645	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SaO55_RS02655	COG4466	Protein conserved in bacteria
SaO55_RS02665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaO55_RS02670	COG0251	oxidation-reduction process
SaO55_RS02715	COG2244	polysaccharide biosynthetic process
SaO55_RS02720	COG3956	TIGRFAM MazG family protein
SaO55_RS02725	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaO55_RS02735	COG1098	S1 RNA binding domain
SaO55_RS02750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaO55_RS02785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SaO55_RS02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaO55_RS02875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaO55_RS02885	COG3880	PFAM UvrB UvrC protein
SaO55_RS02900	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SaO55_RS02905	COG4956	integral membrane protein (PIN domain superfamily)
SaO55_RS02930	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaO55_RS02990	COG2813	Specifically methylates the guanine in position
SaO55_RS03030	COG1473	amidohydrolase
SaO55_RS03065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaO55_RS03070	COG1428	Deoxynucleoside kinase
SaO55_RS03075	COG1428	Deoxynucleoside kinase
SaO55_RS03085	COG0561	phosphatase activity
SaO55_RS03105	COG4932	domain protein
SaO55_RS03130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SaO55_RS03255	COG0095	Lipoate-protein ligase
SaO55_RS03260	COG0083	homoserine kinase activity
SaO55_RS03280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaO55_RS03325	COG0667	Aldo Keto reductase
SaO55_RS03330	COG0655	NAD(P)H dehydrogenase (quinone) activity
SaO55_RS03340	COG1078	dGTPase activity
SaO55_RS03375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SaO55_RS03380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO55_RS03430	COG4974	Belongs to the 'phage' integrase family
SaO55_RS03475	COG0803	Belongs to the bacterial solute-binding protein 9 family
SaO55_RS03480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaO55_RS03485	COG1121	(ABC) transporter
SaO55_RS03490	COG1321	iron dependent repressor
SaO55_RS03500	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SaO55_RS03510	COG1682	transport, permease protein
SaO55_RS03515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SaO55_RS03525	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SaO55_RS03530	COG1686	Belongs to the peptidase S11 family
SaO55_RS03535	COG1132	(ABC) transporter
SaO55_RS03540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaO55_RS03550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaO55_RS03555	COG1120	ATPase activity
SaO55_RS03560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO55_RS03565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO55_RS03570	COG2376	Dihydroxyacetone kinase
SaO55_RS03580	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaO55_RS03590	COG3949	Membrane
SaO55_RS03610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SaO55_RS03625	COG1136	(ABC) transporter
SaO55_RS03630	COG0577	efflux transmembrane transporter activity
SaO55_RS03635	COG1392	Phosphate transport regulator
SaO55_RS03640	COG0306	phosphate transporter
SaO55_RS03645	COG3942	CHAP domain
SaO55_RS03645	COG1388	LysM domain
SaO55_RS03655	COG1917	Cupin 2, conserved barrel domain protein
SaO55_RS03655	COG4977	sequence-specific DNA binding
SaO55_RS03685	COG0583	DNA-binding transcription factor activity
SaO55_RS03695	COG2814	Major facilitator Superfamily
SaO55_RS03700	COG2839	Protein conserved in bacteria
SaO55_RS03730	COG1611	Belongs to the LOG family
SaO55_RS03750	COG4988	ABC transporter
SaO55_RS03755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaO55_RS03765	COG0523	cobalamin synthesis protein
SaO55_RS03770	COG4989	oxidoreductase activity
SaO55_RS03780	COG0471	metal ion transport
SaO55_RS03785	COG0415	Belongs to the DNA photolyase family
SaO55_RS03815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaO55_RS03820	COG1349	DNA-binding transcription factor activity
SaO55_RS03825	COG1105	Belongs to the carbohydrate kinase PfkB family
SaO55_RS03830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaO55_RS03830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaO55_RS03830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaO55_RS03835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SaO55_RS03840	COG1253	flavin adenine dinucleotide binding
SaO55_RS03845	COG0656	L-ascorbic acid biosynthetic process
SaO55_RS03850	COG0463	Glycosyl transferase, family 2
SaO55_RS03885	COG0720	synthase
SaO55_RS03895	COG0512	Glutamine amidotransferase of anthranilate synthase
SaO55_RS03895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SaO55_RS03900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SaO55_RS03930	COG0488	(ABC) transporter
SaO55_RS03935	COG0514	ATP-dependent DNA helicase (RecQ)
SaO55_RS03940	COG1125	glycine betaine transport
SaO55_RS03940	COG0517	IMP dehydrogenase activity
SaO55_RS03945	COG1174	glycine betaine transport
SaO55_RS03970	COG3104	oligopeptide transport
SaO55_RS04000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaO55_RS04005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaO55_RS04015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO55_RS04020	COG4605	iron ion homeostasis
SaO55_RS04030	COG4607	ABC-type enterochelin transport system periplasmic component
SaO55_RS04085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaO55_RS04090	COG1739	Uncharacterized protein family UPF0029
SaO55_RS04100	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SaO55_RS04105	COG1040	competence protein
SaO55_RS04135	COG3942	CHAP domain
SaO55_RS04135	COG1388	LysM domain
SaO55_RS04190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SaO55_RS04210	COG0281	malic enzyme
SaO55_RS04265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SaO55_RS04270	COG1647	Serine aminopeptidase, S33
SaO55_RS04275	COG0557	exoribonuclease II activity
SaO55_RS04335	COG1278	Cold shock
SaO55_RS04375	COG0406	alpha-ribazole phosphatase activity
SaO55_RS04380	COG1279	arginine transmembrane transporter activity
SaO55_RS04405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaO55_RS04410	COG1393	Belongs to the ArsC family
SaO55_RS04425	COG3878	Protein conserved in bacteria
SaO55_RS04430	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SaO55_RS04445	COG2011	ABC-type metal ion transport system permease component
SaO55_RS04450	COG1464	Belongs to the NlpA lipoprotein family
SaO55_RS04455	COG0582	viral genome integration into host DNA
SaO55_RS04560	COG5484	DNA packaging
SaO55_RS04560	COG3728	DNA packaging
SaO55_RS04600	COG0396	ATPase activity
SaO55_RS04605	COG0719	Fe-S assembly protein
SaO55_RS04615	COG0822	iron-sulfur transferase activity
SaO55_RS04635	COG1253	flavin adenine dinucleotide binding
SaO55_RS04645	COG1801	Protein of unknown function DUF72
SaO55_RS04650	COG0730	response to heat
SaO55_RS04665	COG4470	Protein conserved in bacteria
SaO55_RS04675	COG2445	Protein of unknown function DUF86
SaO55_RS04705	COG1696	Membrane protein involved in D-alanine export
SaO55_RS04715	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SaO55_RS04720	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SaO55_RS04725	COG4837	Protein of unknown function (DUF1462)
SaO55_RS04730	COG1252	NADH dehydrogenase
SaO55_RS04740	COG0316	Belongs to the HesB IscA family
SaO55_RS04750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SaO55_RS04755	COG2056	Na+-H+ antiporter family
SaO55_RS04760	COG2050	protein possibly involved in aromatic compounds catabolism
SaO55_RS04815	COG1098	S1 RNA binding domain
SaO55_RS04820	COG1902	pentaerythritol trinitrate reductase activity
SaO55_RS04840	COG0584	glycerophosphoryl diester phosphodiesterase
SaO55_RS04865	COG0398	Pfam SNARE associated Golgi protein
SaO55_RS04905	COG0561	phosphatase activity
SaO55_RS04945	COG1881	PFAM PEBP family protein
SaO55_RS04975	COG0601	transmembrane transport
SaO55_RS04980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaO55_RS04985	COG0444	Belongs to the ABC transporter superfamily
SaO55_RS04990	COG4608	Belongs to the ABC transporter superfamily
SaO55_RS04995	COG4166	transmembrane transport
SaO55_RS05000	COG0747	negative chemotaxis
SaO55_RS05005	COG0444	Belongs to the ABC transporter superfamily
SaO55_RS05010	COG4608	Belongs to the ABC transporter superfamily
SaO55_RS05015	COG0601	transmembrane transport
SaO55_RS05020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaO55_RS05045	COG1164	Oligoendopeptidase f
SaO55_RS05055	COG2346	COG2346, Truncated hemoglobins
SaO55_RS05070	COG2357	RelA SpoT domain protein
SaO55_RS05080	COG0564	pseudouridine synthase activity
SaO55_RS05085	COG2239	Acts as a magnesium transporter
SaO55_RS05090	COG0569	domain protein
SaO55_RS05090	COG0475	glutathione-regulated potassium exporter activity
SaO55_RS05100	COG0628	permease
SaO55_RS05105	COG1115	amino acid carrier protein
SaO55_RS05145	COG0861	Integral membrane protein TerC family
SaO55_RS05155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaO55_RS05160	COG0737	Belongs to the 5'-nucleotidase family
SaO55_RS05175	COG4903	ComK protein
SaO55_RS05190	COG4873	Protein conserved in bacteria
SaO55_RS05240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaO55_RS05250	COG2314	TM2 domain
SaO55_RS05260	COG1575	Belongs to the MenA family. Type 1 subfamily
SaO55_RS05270	COG1169	isochorismate synthase
SaO55_RS05280	COG2267	carboxylic ester hydrolase activity
SaO55_RS05310	COG0436	Aminotransferase
SaO55_RS05315	COG3594	Acyltransferase
SaO55_RS05345	COG1316	TRANSCRIPTIONal
SaO55_RS05390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaO55_RS05405	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaO55_RS05450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SaO55_RS05455	COG4172	Belongs to the ABC transporter superfamily
SaO55_RS05460	COG4721	ABC-type cobalt transport system, permease component
SaO55_RS05480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SaO55_RS05500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaO55_RS05505	COG1271	oxidase subunit
SaO55_RS05510	COG1294	oxidase, subunit
SaO55_RS05515	COG0569	domain protein
SaO55_RS05580	COG1176	ABC-type spermidine putrescine transport system, permease component I
SaO55_RS05585	COG1177	transmembrane transport
SaO55_RS05590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SaO55_RS05615	COG0483	inositol monophosphate 1-phosphatase activity
SaO55_RS05625	COG1217	gtp-binding protein TYPA
SaO55_RS05635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SaO55_RS05645	COG0772	Belongs to the SEDS family
SaO55_RS05680	COG3679	Belongs to the UPF0342 family
SaO55_RS05700	COG0742	ribosomal rna small subunit methyltransferase
SaO55_RS05760	COG4509	Sortase family
SaO55_RS05775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaO55_RS05820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SaO55_RS05820	COG1796	DNA polymerase
SaO55_RS05845	COG2009	succinate dehydrogenase
SaO55_RS05850	COG1053	succinate dehydrogenase
SaO55_RS05855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SaO55_RS05970	COG1288	antiporter activity
SaO55_RS06005	COG1011	Hydrolase
SaO55_RS06030	COG4839	cell division protein FtsL
SaO55_RS06035	COG0768	penicillin binding
SaO55_RS06055	COG0849	cell division
SaO55_RS06070	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaO55_RS06080	COG0762	integral membrane protein
SaO55_RS06085	COG2302	S4 RNA-binding domain
SaO55_RS06090	COG3599	regulation of cell shape
SaO55_RS06100	COG2514	catechol 2,3-dioxygenase activity
SaO55_RS06115	COG0564	pseudouridine synthase activity
SaO55_RS06125	COG2233	PERMEase
SaO55_RS06170	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SaO55_RS06185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaO55_RS06190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaO55_RS06200	COG2314	TM2 domain
SaO55_RS06215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaO55_RS06215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaO55_RS06225	COG0631	protein serine/threonine phosphatase activity
SaO55_RS06240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SaO55_RS06255	COG1302	Protein conserved in bacteria
SaO55_RS06305	COG1196	nuclear chromosome segregation
SaO55_RS06310	COG0552	protein localization to endoplasmic reticulum
SaO55_RS06320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SaO55_RS06380	COG2348	transferase activity, transferring amino-acyl groups
SaO55_RS06385	COG0758	DNA mediated transformation
SaO55_RS06485	COG0195	Participates in both transcription termination and antitermination
SaO55_RS06490	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaO55_RS06515	COG0196	riboflavin kinase activity
SaO55_RS06545	COG2188	Transcriptional regulator
SaO55_RS06550	COG0612	Peptidase, M16
SaO55_RS06555	COG0612	Peptidase, M16
SaO55_RS06560	COG0300	oxidoreductase activity
SaO55_RS06580	COG1058	Belongs to the CinA family
SaO55_RS06580	COG1546	Belongs to the CinA family
SaO55_RS06600	COG1692	metallophosphoesterase
SaO55_RS06605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SaO55_RS06605	COG0674	pyruvate-flavodoxin oxidoreductase activity
SaO55_RS06610	COG1013	pyruvate-flavodoxin oxidoreductase activity
SaO55_RS06645	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SaO55_RS06650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaO55_RS06710	COG3645	SOS response
SaO55_RS06710	COG3646	Phage regulatory protein
SaO55_RS06775	COG0305	Participates in initiation and elongation during chromosome replication
SaO55_RS06880	COG1783	phage Terminase large subunit
SaO55_RS06980	COG1388	LysM domain
SaO55_RS06980	COG5632	N-Acetylmuramoyl-L-alanine amidase
SaO55_RS07005	COG1923	regulation of RNA biosynthetic process
SaO55_RS07015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SaO55_RS07020	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SaO55_RS07025	COG0789	Transcriptional regulator
SaO55_RS07115	COG1525	nuclease
SaO55_RS07130	COG0527	aspartate kinase activity
SaO55_RS07135	COG0460	homoserine dehydrogenase
SaO55_RS07140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SaO55_RS07165	COG0833	amino acid
SaO55_RS07195	COG2340	Cysteine-rich secretory protein family
SaO55_RS07230	COG4846	Membrane protein involved in cytochrome C biogenesis
SaO55_RS07250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaO55_RS07260	COG0824	Thioesterase
SaO55_RS07290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SaO55_RS07300	COG1115	amino acid carrier protein
SaO55_RS07315	COG0628	permease
SaO55_RS07340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SaO55_RS07350	COG1363	Peptidase, m42
SaO55_RS07355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SaO55_RS07360	COG0512	Glutamine amidotransferase of anthranilate synthase
SaO55_RS07420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SaO55_RS07485	COG0704	Plays a role in the regulation of phosphate uptake
SaO55_RS07495	COG0581	inorganic phosphate transmembrane transporter activity
SaO55_RS07500	COG0573	inorganic phosphate transmembrane transporter activity
SaO55_RS07515	COG0488	(ABC) transporter
SaO55_RS07525	COG0527	aspartate kinase activity
SaO55_RS07530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaO55_RS07565	COG2808	Putative FMN-binding domain
SaO55_RS07610	COG4548	von Willebrand factor, type A
SaO55_RS07615	COG0714	Associated with various cellular activities
SaO55_RS07655	COG0671	phosphoesterase, PA-phosphatase related
SaO55_RS07730	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SaO55_RS07750	COG0531	amino acid
SaO55_RS07765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaO55_RS07770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SaO55_RS07785	COG0116	Belongs to the methyltransferase superfamily
SaO55_RS07825	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaO55_RS07825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaO55_RS07835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaO55_RS07840	COG3935	DnaD domain protein
SaO55_RS07865	COG0438	transferase activity, transferring glycosyl groups
SaO55_RS07870	COG1694	Mazg nucleotide pyrophosphohydrolase
SaO55_RS07875	COG2738	Putative neutral zinc metallopeptidase
SaO55_RS07880	COG4347	Protein of unknown function (DUF1405)
SaO55_RS07915	COG0142	geranyltranstransferase activity
SaO55_RS07980	COG0492	ferredoxin-NADP+ reductase activity
SaO55_RS07995	COG0514	ATP-dependent DNA helicase (RecQ)
SaO55_RS08005	COG1141	Ferredoxin
SaO55_RS08035	COG5002	protein histidine kinase activity
SaO55_RS08040	COG0745	RESPONSE REGULATOR receiver
SaO55_RS08045	COG1187	pseudouridine synthase activity
SaO55_RS08070	COG0735	belongs to the Fur family
SaO55_RS08075	COG0494	nUDIX hydrolase
SaO55_RS08080	COG0667	Aldo Keto reductase
SaO55_RS08090	COG4221	oxidoreductase activity
SaO55_RS08105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SaO55_RS08115	COG0366	Alpha amylase catalytic
SaO55_RS08120	COG1609	Transcriptional regulator
SaO55_RS08140	COG2195	Cleaves the N-terminal amino acid of tripeptides
SaO55_RS08150	COG4129	membrane
SaO55_RS08160	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaO55_RS08165	COG0022	dehydrogenase e1 component
SaO55_RS08170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaO55_RS08175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaO55_RS08180	COG0497	DNA recombination
SaO55_RS08210	COG1302	Protein conserved in bacteria
SaO55_RS08215	COG0439	Biotin carboxylase
SaO55_RS08220	COG0511	ligase activity, forming carbon-carbon bonds
SaO55_RS08230	COG0006	proline dipeptidase activity
SaO55_RS08245	COG0095	Lipoate-protein ligase
SaO55_RS08250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SaO55_RS08295	COG4537	Required for transformation and DNA binding
SaO55_RS08300	COG1459	type II secretion system
SaO55_RS08305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaO55_RS08310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SaO55_RS08315	COG0011	TIGRFAM Protein of
SaO55_RS08320	COG1940	carbohydrate kinase activity
SaO55_RS08325	COG4483	Protein conserved in bacteria
SaO55_RS08335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaO55_RS08345	COG0768	penicillin binding
SaO55_RS08360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaO55_RS08365	COG1121	(ABC) transporter
SaO55_RS08375	COG0513	Belongs to the DEAD box helicase family
SaO55_RS08385	COG2384	SAM-dependent methyltransferase
SaO55_RS08405	COG0517	IMP dehydrogenase activity
SaO55_RS08425	COG0295	cytidine deaminase activity
SaO55_RS08440	COG1702	phosphate starvation-inducible protein PhoH
SaO55_RS08455	COG1030	water channel activity
SaO55_RS08465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SaO55_RS08470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaO55_RS08500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaO55_RS08525	COG1466	dna polymerase III delta subunit
SaO55_RS08530	COG0658	competence protein
SaO55_RS08530	COG2333	competence protein COMEC
SaO55_RS08535	COG2131	deaminase
SaO55_RS08540	COG2183	response to ionizing radiation
SaO55_RS08545	COG2226	methyltransferase
SaO55_RS08550	COG0799	negative regulation of ribosome biogenesis
SaO55_RS08555	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaO55_RS08565	COG1534	Rna-binding protein
SaO55_RS08575	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaO55_RS08580	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SaO55_RS08600	COG3177	Filamentation induced by cAMP protein fic
SaO55_RS08605	COG1914	H( )-stimulated, divalent metal cation uptake system
SaO55_RS08615	COG0439	Biotin carboxylase
SaO55_RS08620	COG0511	ligase activity, forming carbon-carbon bonds
SaO55_RS08625	COG1984	allophanate hydrolase subunit 2
SaO55_RS08630	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SaO55_RS08645	COG0826	peptidase U32
SaO55_RS08650	COG0826	peptidase U32
SaO55_RS08680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaO55_RS08695	COG1104	cysteine desulfurase activity
SaO55_RS08700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SaO55_RS08710	COG3237	CsbD-like
SaO55_RS08715	COG1959	2 iron, 2 sulfur cluster binding
SaO55_RS08720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaO55_RS08725	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SaO55_RS08770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SaO55_RS08770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SaO55_RS08775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SaO55_RS08775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SaO55_RS08780	COG1862	Preprotein translocase
SaO55_RS08820	COG2868	ribosomal protein
SaO55_RS08865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SaO55_RS08875	COG0285	dihydrofolate synthase activity
SaO55_RS08885	COG2818	Glycosylase
SaO55_RS08920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SaO55_RS08955	COG4112	unkown
SaO55_RS08980	COG0833	amino acid
SaO55_RS08995	COG1484	DNA-dependent DNA replication
SaO55_RS09025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaO55_RS09025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaO55_RS09035	COG5002	protein histidine kinase activity
SaO55_RS09040	COG0745	RESPONSE REGULATOR receiver
SaO55_RS09055	COG0372	Belongs to the citrate synthase family
SaO55_RS09060	COG1113	amino acid transport
SaO55_RS09085	COG0281	malic enzyme
SaO55_RS09095	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaO55_RS09105	COG4109	DRTGG domain
SaO55_RS09145	COG0827	DNA restriction-modification system
SaO55_RS09155	COG0730	response to heat
SaO55_RS09165	COG1104	cysteine desulfurase activity
SaO55_RS09175	COG1956	GAF domain-containing protein
SaO55_RS09195	COG0584	glycerophosphoryl diester phosphodiesterase
SaO55_RS09200	COG1764	response to oxidative stress
SaO55_RS09205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SaO55_RS09210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SaO55_RS09225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO55_RS09225	COG1263	PTS System
SaO55_RS09230	COG0204	Acyl-transferase
SaO55_RS09235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SaO55_RS09270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SaO55_RS09275	COG0454	-acetyltransferase
SaO55_RS09295	COG1605	Chorismate mutase
SaO55_RS09295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaO55_RS09320	COG1674	ftsk spoiiie
SaO55_RS09325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaO55_RS09335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaO55_RS09340	COG1363	Peptidase, m42
SaO55_RS09350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SaO55_RS09360	COG0510	thiamine kinase activity
SaO55_RS09380	COG1187	pseudouridine synthase activity
SaO55_RS09385	COG2244	polysaccharide biosynthetic process
SaO55_RS09390	COG2081	HI0933 family
SaO55_RS09410	COG2814	Major facilitator Superfamily
SaO55_RS09415	COG1242	4 iron, 4 sulfur cluster binding
SaO55_RS09420	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaO55_RS09430	COG2267	carboxylic ester hydrolase activity
SaO55_RS09465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SaO55_RS09465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SaO55_RS09490	COG5632	N-Acetylmuramoyl-L-alanine amidase
SaO55_RS09490	COG3266	domain, Protein
SaO55_RS09490	COG4193	domain, Protein
SaO55_RS09520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SaO55_RS09540	COG0656	L-ascorbic acid biosynthetic process
SaO55_RS09560	COG1506	peptidase
SaO55_RS09565	COG2816	NAD+ diphosphatase activity
SaO55_RS09610	COG5492	domain, Protein
SaO55_RS09690	COG1131	(ABC) transporter
SaO55_RS09810	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SaO55_RS09840	COG1131	(ABC) transporter
SaO55_RS09845	COG0537	adenosine 5'-monophosphoramidase activity
SaO55_RS09880	COG0420	3'-5' exonuclease activity
SaO55_RS09910	COG2197	response regulator
SaO55_RS09915	COG4585	Histidine kinase
SaO55_RS09915	COG2203	Gaf domain
SaO55_RS09920	COG0564	pseudouridine synthase activity
SaO55_RS09955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaO55_RS09960	COG1126	abc transporter atp-binding protein
SaO55_RS09965	COG0765	amino acid transport
SaO55_RS10130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SaO55_RS10135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SaO55_RS10145	COG4129	membrane
SaO55_RS10165	COG1988	membrane-bound metal-dependent
SaO55_RS10180	COG1388	LysM domain
SaO55_RS10180	COG1134	teichoic acid transport
SaO55_RS10210	COG0535	radical SAM domain protein
SaO55_RS10215	COG1607	acyl-coa hydrolase
SaO55_RS10220	COG2309	aminopeptidase activity
SaO55_RS10240	COG1295	ribonuclease BN
SaO55_RS10245	COG2197	response regulator
SaO55_RS10365	COG1733	regulation of RNA biosynthetic process
SaO55_RS10375	COG4851	CamS sex pheromone cAM373 precursor
SaO55_RS10395	COG4496	protein, YerC YecD
SaO55_RS10435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaO55_RS10445	COG0077	Prephenate dehydratase
SaO55_RS10455	COG0471	metal ion transport
SaO55_RS10465	COG1335	isochorismatase
SaO55_RS10480	COG1012	belongs to the aldehyde dehydrogenase family
SaO55_RS10490	COG3682	Transcriptional regulator
SaO55_RS10520	COG4974	Belongs to the 'phage' integrase family
SaO55_RS10570	COG1131	(ABC) transporter
SaO55_RS10585	COG1725	Transcriptional regulator
SaO55_RS10640	COG0156	8-amino-7-oxononanoate synthase activity
SaO55_RS10645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaO55_RS10745	COG0582	viral genome integration into host DNA
SaO55_RS10810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaO55_RS10815	COG1621	beta-fructofuranosidase activity
SaO55_RS10820	COG1609	Transcriptional regulator
SaO55_RS10825	COG0004	ammonium transporteR
SaO55_RS10830	COG0425	Belongs to the sulfur carrier protein TusA family
SaO55_RS10835	COG2391	methyltransferase activity
SaO55_RS10845	COG0488	(ABC) transporter
SaO55_RS10860	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SaO55_RS10870	COG0456	acetyltransferase
SaO55_RS10875	COG1214	PFAM Peptidase M22, glycoprotease
SaO55_RS10880	COG0802	atpase or kinase
SaO55_RS10895	COG0028	Belongs to the TPP enzyme family
SaO55_RS10970	COG2183	response to ionizing radiation
SaO55_RS10975	COG1191	sigma factor activity
SaO55_RS10985	COG1366	Belongs to the anti-sigma-factor antagonist family
SaO55_RS10990	COG2208	phosphoserine phosphatase activity
SaO55_RS11025	COG3428	Bacterial PH domain
SaO55_RS11055	COG2205	protein histidine kinase activity
SaO55_RS11060	COG0745	RESPONSE REGULATOR receiver
SaO55_RS11070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaO55_RS11080	COG0772	Belongs to the SEDS family
SaO55_RS11095	COG1937	Protein conserved in bacteria
SaO55_RS11105	COG1418	mRNA catabolic process
SaO55_RS11150	COG0629	single-stranded DNA binding
SaO55_RS11235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SaO55_RS11260	COG0009	L-threonylcarbamoyladenylate synthase
SaO55_RS11265	COG2890	protein-(glutamine-N5) methyltransferase activity
SaO55_RS11290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SaO55_RS11330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SaO55_RS11380	COG0813	purine-nucleoside phosphorylase activity
SaO55_RS11385	COG0783	Belongs to the Dps family
SaO55_RS11405	COG1482	cell wall glycoprotein biosynthetic process
SaO55_RS11410	COG0702	epimerase
SaO55_RS11415	COG0640	Transcriptional regulator
SaO55_RS11435	COG0561	phosphatase activity
SaO55_RS11440	COG1119	ATPase activity
SaO55_RS11455	COG3711	transcriptional antiterminator
SaO55_RS11485	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaO55_RS11540	COG0489	protein tyrosine kinase activity
SaO55_RS11545	COG2814	Major facilitator Superfamily
SaO55_RS11560	COG1272	protein, Hemolysin III
SaO55_RS11570	COG1988	membrane-bound metal-dependent
SaO55_RS11580	COG3314	Sporulation integral membrane protein YlbJ
SaO55_RS11585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO55_RS11590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaO55_RS11595	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaO55_RS11605	COG3457	Alanine racemase
SaO55_RS11610	COG4264	IucA IucC family
SaO55_RS11615	COG2814	Major facilitator Superfamily
SaO55_RS11640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaO55_RS11650	COG2130	NADP-dependent
SaO55_RS11710	COG0656	L-ascorbic acid biosynthetic process
SaO55_RS11715	COG0789	Transcriptional regulator
SaO55_RS11725	COG5492	domain, Protein
SaO55_RS11745	COG3527	Alpha-acetolactate decarboxylase
SaO55_RS11750	COG0028	Belongs to the TPP enzyme family
SaO55_RS11830	COG0201	protein transport
SaO55_RS11945	COG2252	PERMEase
SaO55_RS11990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SaO55_RS12050	COG1763	Mo-molybdopterin cofactor biosynthetic process
SaO55_RS12070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SaO55_RS12075	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SaO55_RS12080	COG4149	molybdate abc transporter
SaO55_RS12085	COG0725	ABC transporter, periplasmic molybdate-binding protein
SaO55_RS12100	COG1268	BioY protein
SaO55_RS12115	COG1960	acyl-CoA dehydrogenase activity
SaO55_RS12120	COG4413	Urea transporter
SaO55_RS12195	COG1757	Na H antiporter
SaO55_RS12210	COG3942	CHAP domain
SaO55_RS12285	COG1113	amino acid transport
SaO55_RS12305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaO55_RS12310	COG0385	Bile acid
SaO55_RS12320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO55_RS12320	COG1263	PTS System
SaO55_RS12325	COG1737	Transcriptional regulator
SaO55_RS12345	COG1028	Short-chain dehydrogenase reductase Sdr
SaO55_RS12350	COG1473	amidohydrolase
SaO55_RS12365	COG0583	DNA-binding transcription factor activity
SaO55_RS12390	COG2258	MOSC domain
SaO55_RS12410	COG1668	transmembrane transport
SaO55_RS12415	COG4152	abc transporter atp-binding protein
SaO55_RS12420	COG3152	Membrane
SaO55_RS12435	COG0786	glutamate:sodium symporter activity
SaO55_RS12445	COG0598	Magnesium transport protein CorA
SaO55_RS12460	COG0657	acetylesterase activity
SaO55_RS12470	COG2814	Major facilitator Superfamily
SaO55_RS12475	COG1566	PFAM secretion protein HlyD family protein
SaO55_RS12485	COG2814	Major facilitator Superfamily
SaO55_RS12555	COG1131	(ABC) transporter
SaO55_RS12570	COG1620	l-lactate permease
SaO55_RS12590	COG0604	alcohol dehydrogenase
SaO55_RS12620	COG1511	domain protein
SaO55_RS12635	COG1263	PTS System
SaO55_RS12635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaO55_RS12650	COG3871	stress protein (general stress protein 26)
SaO55_RS12705	COG2181	nitrate reductase activity
SaO55_RS12715	COG1140	nitrate reductase beta subunit
SaO55_RS12720	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SaO55_RS12730	COG2146	nitrite reductase [NAD(P)H] activity
SaO55_RS12735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SaO55_RS12745	COG0454	-acetyltransferase
SaO55_RS12755	COG2116	formate transmembrane transporter activity
SaO55_RS12770	COG0803	Belongs to the bacterial solute-binding protein 9 family
SaO55_RS12770	COG3443	Belongs to the bacterial solute-binding protein 9 family
SaO55_RS12805	COG1126	abc transporter atp-binding protein
SaO55_RS12810	COG0765	amino acid transport
SaO55_RS12815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaO55_RS12820	COG2814	Major facilitator Superfamily
SaO55_RS12835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaO55_RS12880	COG0156	8-amino-7-oxononanoate synthase activity
SaO55_RS12890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SaO55_RS12895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SaO55_RS12910	COG1132	(ABC) transporter
SaO55_RS12915	COG1132	(ABC) transporter
SaO55_RS12915	COG2375	cellular response to nickel ion
SaO55_RS12935	COG1929	Belongs to the glycerate kinase type-1 family
SaO55_RS12945	COG2814	Major facilitator Superfamily
SaO55_RS12960	COG1408	metallophosphoesterase
SaO55_RS12965	COG1113	amino acid transport
SaO55_RS12980	COG0531	amino acid
SaO55_RS13005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SaO55_RS13015	COG1174	glycine betaine transport
SaO55_RS13025	COG1174	glycine betaine transport
SaO55_RS13045	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SaO55_RS13050	COG0531	amino acid
SaO55_RS13055	COG2272	Belongs to the type-B carboxylesterase lipase family
SaO55_RS13060	COG2814	Major facilitator Superfamily
SaO55_RS13065	COG0390	transport system, permease component
SaO55_RS13070	COG4619	ABC transporter
SaO55_RS13075	COG1363	Peptidase, m42
SaO55_RS13095	COG4808	Protein conserved in bacteria
SaO55_RS13100	COG0069	glutamate synthase activity
SaO55_RS13115	COG1124	(ABC) transporter
SaO55_RS13125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaO55_RS13130	COG0601	transmembrane transport
SaO55_RS13135	COG0747	negative chemotaxis
SaO55_RS13160	COG1028	Short-chain dehydrogenase reductase Sdr
SaO55_RS13165	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SaO55_RS13170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SaO55_RS13260	COG0494	nUDIX hydrolase
SaO55_RS13315	COG1070	Carbohydrate kinase
SaO55_RS13320	COG1802	Transcriptional regulator
SaO55_RS13325	COG0789	Transcriptional regulator
SaO55_RS13330	COG2357	RelA SpoT domain protein
SaO55_RS13335	COG4876	unkown
SaO55_RS13350	COG2271	Major facilitator Superfamily
SaO55_RS13355	COG0586	Pfam SNARE associated Golgi protein
SaO55_RS13365	COG2814	Major facilitator Superfamily
SaO55_RS13370	COG1846	Transcriptional regulator
SaO55_RS13385	COG1131	(ABC) transporter
SaO55_RS13405	COG0400	carboxylic ester hydrolase activity
SaO55_RS13410	COG0346	lactoylglutathione lyase activity
SaO55_RS13415	COG1846	Transcriptional regulator
SaO55_RS13425	COG2514	catechol 2,3-dioxygenase activity
SaO55_RS13440	COG0561	phosphatase activity
SaO55_RS13445	COG1131	(ABC) transporter
SaO55_RS13455	COG3764	Sortase (surface protein transpeptidase)
SaO55_RS13475	COG1760	l-serine dehydratase
SaO55_RS13480	COG1760	l-serine dehydratase
SaO55_RS13495	COG0697	spore germination
SaO55_RS13500	COG0657	acetylesterase activity
SaO55_RS13525	COG0028	Belongs to the TPP enzyme family
SaO55_RS13540	COG0583	DNA-binding transcription factor activity
SaO55_RS13550	COG3942	CHAP domain
SaO55_RS13560	COG3425	synthase
SaO55_RS13565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaO55_RS13590	COG2409	Drug exporters of the RND superfamily
SaO55_RS13635	COG0436	Aminotransferase
SaO55_RS13675	COG0456	acetyltransferase
SaO55_RS13740	COG0596	Alpha beta hydrolase
SaO55_RS13780	COG3001	Fructosamine kinase
SaO55_RS13785	COG0167	dihydroorotate dehydrogenase activity
SaO55_RS13835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SaO55_RS13840	COG3527	Alpha-acetolactate decarboxylase
SaO55_RS13855	COG0531	amino acid
SaO55_RS13885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SaO55_RS13905	COG1012	belongs to the aldehyde dehydrogenase family
SaO55_RS13915	COG1510	regulation of RNA biosynthetic process
SaO55_RS13920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaO55_RS13945	COG2851	Citrate transporter
SaO55_RS13955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SaO55_RS13965	COG0386	Belongs to the glutathione peroxidase family
SaO55_RS13990	COG1136	(ABC) transporter
SaO55_RS13995	COG2205	protein histidine kinase activity
SaO55_RS14000	COG0745	RESPONSE REGULATOR receiver
SaO55_RS14010	COG1785	Belongs to the alkaline phosphatase family
SaO55_RS14020	COG1846	Transcriptional regulator
SaO55_RS14065	COG1438	arginine binding
SaO55_RS14085	COG3711	transcriptional antiterminator
SaO55_RS14085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaO55_RS14090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaO55_RS14090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaO55_RS14090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaO55_RS14095	COG1482	cell wall glycoprotein biosynthetic process
SaO55_RS14105	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaO55_RS14105	COG3942	CHAP domain
SaO55_RS14110	COG1535	isochorismatase
SaO55_RS14110	COG3433	isochorismatase activity
SaO55_RS14125	COG0438	transferase activity, transferring glycosyl groups
SaO55_RS14140	COG1073	alpha beta
SaO55_RS14160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SaO55_RS14190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SaO55_RS14275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SaO55_RS14335	COG0471	metal ion transport
SaO55_RS14340	COG2962	Rard protein
SaO55_RS14350	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SaO55_RS14365	COG1136	(ABC) transporter
SaO55_RS14370	COG0577	efflux transmembrane transporter activity
SaO55_RS14380	COG1278	Cold shock
SaO55_RS14405	COG1475	DNA binding