locus-tag	class	description
EFD73_RS00055	COG2501	S4 domain
EFD73_RS00075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EFD73_RS00110	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EFD73_RS00120	COG0305	Participates in initiation and elongation during chromosome replication
EFD73_RS00150	COG4863	YycH protein
EFD73_RS00160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EFD73_RS00165	COG0737	Belongs to the 5'-nucleotidase family
EFD73_RS00190	COG0584	glycerophosphoryl diester phosphodiesterase
EFD73_RS00195	COG2030	dehydratase
EFD73_RS00220	COG1846	Transcriptional regulator
EFD73_RS00220	COG1940	carbohydrate kinase activity
EFD73_RS00230	COG2210	Belongs to the sulfur carrier protein TusA family
EFD73_RS00235	COG1937	Protein conserved in bacteria
EFD73_RS00240	COG0730	response to heat
EFD73_RS00250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EFD73_RS00285	COG2003	Belongs to the UPF0758 family
EFD73_RS00340	COG0745	RESPONSE REGULATOR receiver
EFD73_RS00345	COG2205	protein histidine kinase activity
EFD73_RS00415	COG0730	response to heat
EFD73_RS00420	COG1937	Protein conserved in bacteria
EFD73_RS00425	COG2210	Belongs to the sulfur carrier protein TusA family
EFD73_RS00430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EFD73_RS00475	COG0823	Involved in the tonB-independent uptake of proteins
EFD73_RS00510	COG1473	amidohydrolase
EFD73_RS00520	COG1283	sodium-dependent phosphate transmembrane transporter activity
EFD73_RS00525	COG4716	Myosin-crossreactive antigen
EFD73_RS00530	COG0697	spore germination
EFD73_RS00545	COG1620	l-lactate permease
EFD73_RS00550	COG1388	LysM domain
EFD73_RS00560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD73_RS00565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD73_RS00570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EFD73_RS00580	COG2423	ornithine cyclodeaminase activity
EFD73_RS00585	COG4264	IucA IucC family
EFD73_RS00590	COG2814	Major facilitator Superfamily
EFD73_RS00595	COG4264	IucA IucC family
EFD73_RS00600	COG4264	IucA IucC family
EFD73_RS00610	COG0019	diaminopimelate decarboxylase activity
EFD73_RS00615	COG1475	DNA binding
EFD73_RS00635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EFD73_RS00640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EFD73_RS00645	COG0438	transferase activity, transferring glycosyl groups
EFD73_RS00675	COG0813	purine-nucleoside phosphorylase activity
EFD73_RS00680	COG2814	Major facilitator Superfamily
EFD73_RS00700	COG3639	organic phosphonate transmembrane transporter activity
EFD73_RS00720	COG0737	Belongs to the 5'-nucleotidase family
EFD73_RS00760	COG1086	Polysaccharide biosynthesis protein
EFD73_RS00770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EFD73_RS00800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EFD73_RS00810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EFD73_RS00815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EFD73_RS00825	COG2832	Protein of unknown function (DUF454)
EFD73_RS00860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EFD73_RS00865	COG1960	acyl-CoA dehydrogenase activity
EFD73_RS00870	COG5609	conserved protein (DUF2294)
EFD73_RS00920	COG1114	Component of the transport system for branched-chain amino acids
EFD73_RS00925	COG1335	isochorismatase
EFD73_RS00930	COG3961	Belongs to the TPP enzyme family
EFD73_RS00960	COG1737	Transcriptional regulator
EFD73_RS00985	COG1136	(ABC) transporter
EFD73_RS00990	COG1136	(ABC) transporter
EFD73_RS00990	COG0577	efflux transmembrane transporter activity
EFD73_RS01010	COG1131	(ABC) transporter
EFD73_RS01025	COG0601	transmembrane transport
EFD73_RS01030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFD73_RS01040	COG0405	Gamma-glutamyltransferase
EFD73_RS01060	COG3842	ATPase activity
EFD73_RS01070	COG1175	transmembrane transport
EFD73_RS01075	COG3833	ABC-type maltose transport systems, permease component
EFD73_RS01080	COG0673	inositol 2-dehydrogenase activity
EFD73_RS01085	COG0673	inositol 2-dehydrogenase activity
EFD73_RS01095	COG1755	Isoprenylcysteine carboxyl methyltransferase
EFD73_RS01150	COG0183	Belongs to the thiolase family
EFD73_RS01160	COG1960	acyl-CoA dehydrogenase activity
EFD73_RS01165	COG0318	PFAM AMP-dependent synthetase and ligase
EFD73_RS01180	COG0747	negative chemotaxis
EFD73_RS01185	COG3189	MarR family transcriptional regulator
EFD73_RS01210	COG2190	(PTS) system
EFD73_RS01210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD73_RS01210	COG1263	PTS System
EFD73_RS01215	COG1957	nucleoside hydrolase
EFD73_RS01235	COG3414	Phosphotransferase system galactitol-specific IIB component
EFD73_RS01240	COG3775	system Galactitol-specific IIC component
EFD73_RS01245	COG1063	alcohol dehydrogenase
EFD73_RS01255	COG1063	alcohol dehydrogenase
EFD73_RS01265	COG1063	alcohol dehydrogenase
EFD73_RS01270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EFD73_RS01275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EFD73_RS01285	COG1063	alcohol dehydrogenase
EFD73_RS01290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EFD73_RS01325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EFD73_RS01330	COG2190	(PTS) system
EFD73_RS01330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD73_RS01330	COG1263	PTS System
EFD73_RS01335	COG2723	6-phospho-beta-galactosidase activity
EFD73_RS01340	COG2226	methyltransferase
EFD73_RS01395	COG1131	(ABC) transporter
EFD73_RS01415	COG3942	CHAP domain
EFD73_RS01415	COG1388	LysM domain
EFD73_RS01535	COG1114	Component of the transport system for branched-chain amino acids
EFD73_RS01540	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EFD73_RS01545	COG0577	efflux transmembrane transporter activity
EFD73_RS01575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFD73_RS01580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFD73_RS01605	COG3314	Sporulation integral membrane protein YlbJ
EFD73_RS01630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFD73_RS01660	COG3037	sugar-specific permease SgaT UlaA
EFD73_RS01670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD73_RS01675	COG3711	transcriptional antiterminator
EFD73_RS01695	COG2271	Major facilitator Superfamily
EFD73_RS01700	COG0346	lactoylglutathione lyase activity
EFD73_RS01705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFD73_RS01710	COG0431	NADPH-dependent FMN reductase
EFD73_RS01720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EFD73_RS01725	COG2822	iron ion transport
EFD73_RS01735	COG0672	)-iron permease
EFD73_RS01740	COG0805	protein transport
EFD73_RS01745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EFD73_RS01755	COG1476	TRANSCRIPTIONal
EFD73_RS01765	COG1131	(ABC) transporter
EFD73_RS01795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EFD73_RS01795	COG0646	methionine synthase
EFD73_RS01800	COG0626	cystathionine gamma-synthase activity
EFD73_RS01805	COG0626	cystathionine gamma-synthase activity
EFD73_RS01810	COG1475	DNA binding
EFD73_RS01815	COG0668	transmembrane transport
EFD73_RS01820	COG4481	Protein conserved in bacteria
EFD73_RS01825	COG0012	GTP binding
EFD73_RS01925	COG1823	symporter activity
EFD73_RS01955	COG2233	PERMEase
EFD73_RS01990	COG3759	membrane
EFD73_RS02150	COG0523	cobalamin synthesis protein
EFD73_RS02175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EFD73_RS02185	COG5609	conserved protein (DUF2294)
EFD73_RS02200	COG1647	Serine aminopeptidase, S33
EFD73_RS02205	COG0733	neurotransmitter:sodium symporter activity
EFD73_RS02210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EFD73_RS02215	COG0626	cystathionine gamma-synthase activity
EFD73_RS02225	COG2011	ABC-type metal ion transport system permease component
EFD73_RS02230	COG1464	Belongs to the NlpA lipoprotein family
EFD73_RS02265	COG0583	DNA-binding transcription factor activity
EFD73_RS02270	COG0070	glutamate synthase
EFD73_RS02270	COG0069	glutamate synthase activity
EFD73_RS02270	COG0067	glutamate synthase
EFD73_RS02275	COG0493	'glutamate synthase
EFD73_RS02285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD73_RS02285	COG1263	PTS System
EFD73_RS02290	COG0366	Alpha amylase catalytic
EFD73_RS02295	COG2188	Transcriptional regulator
EFD73_RS02315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFD73_RS02350	COG1982	Orn Lys Arg decarboxylase major
EFD73_RS02360	COG3870	Protein conserved in bacteria
EFD73_RS02365	COG0470	DNA polymerase III
EFD73_RS02370	COG1774	PSP1 C-terminal conserved region
EFD73_RS02380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EFD73_RS02390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EFD73_RS02400	COG0084	hydrolase, TatD family'
EFD73_RS02405	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EFD73_RS02415	COG4466	Protein conserved in bacteria
EFD73_RS02425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFD73_RS02430	COG0251	oxidation-reduction process
EFD73_RS02470	COG2244	polysaccharide biosynthetic process
EFD73_RS02475	COG3956	TIGRFAM MazG family protein
EFD73_RS02480	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EFD73_RS02490	COG1098	S1 RNA binding domain
EFD73_RS02505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EFD73_RS02530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EFD73_RS02625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EFD73_RS02640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFD73_RS02650	COG3880	PFAM UvrB UvrC protein
EFD73_RS02665	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EFD73_RS02670	COG4956	integral membrane protein (PIN domain superfamily)
EFD73_RS02690	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EFD73_RS02750	COG2813	Specifically methylates the guanine in position
EFD73_RS02790	COG1473	amidohydrolase
EFD73_RS02820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EFD73_RS02825	COG1428	Deoxynucleoside kinase
EFD73_RS02830	COG1428	Deoxynucleoside kinase
EFD73_RS02840	COG0561	phosphatase activity
EFD73_RS02880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EFD73_RS02895	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EFD73_RS02985	COG0095	Lipoate-protein ligase
EFD73_RS02990	COG0083	homoserine kinase activity
EFD73_RS03010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EFD73_RS03045	COG0667	Aldo Keto reductase
EFD73_RS03050	COG0655	NAD(P)H dehydrogenase (quinone) activity
EFD73_RS03060	COG1078	dGTPase activity
EFD73_RS03095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EFD73_RS03100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD73_RS03150	COG4974	Belongs to the 'phage' integrase family
EFD73_RS03200	COG0803	Belongs to the bacterial solute-binding protein 9 family
EFD73_RS03205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EFD73_RS03210	COG1121	(ABC) transporter
EFD73_RS03215	COG1321	iron dependent repressor
EFD73_RS03225	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EFD73_RS03235	COG1682	transport, permease protein
EFD73_RS03240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EFD73_RS03250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EFD73_RS03255	COG1686	Belongs to the peptidase S11 family
EFD73_RS03260	COG1132	(ABC) transporter
EFD73_RS03265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFD73_RS03275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFD73_RS03280	COG1120	ATPase activity
EFD73_RS03285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD73_RS03290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD73_RS03295	COG2376	Dihydroxyacetone kinase
EFD73_RS03305	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EFD73_RS03315	COG3949	Membrane
EFD73_RS03335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EFD73_RS03350	COG1136	(ABC) transporter
EFD73_RS03355	COG0577	efflux transmembrane transporter activity
EFD73_RS03360	COG1392	Phosphate transport regulator
EFD73_RS03365	COG0306	phosphate transporter
EFD73_RS03370	COG3942	CHAP domain
EFD73_RS03370	COG1388	LysM domain
EFD73_RS03380	COG1917	Cupin 2, conserved barrel domain protein
EFD73_RS03380	COG4977	sequence-specific DNA binding
EFD73_RS03410	COG0583	DNA-binding transcription factor activity
EFD73_RS03415	COG2814	Major facilitator Superfamily
EFD73_RS03420	COG2839	Protein conserved in bacteria
EFD73_RS03450	COG1611	Belongs to the LOG family
EFD73_RS03470	COG4988	ABC transporter
EFD73_RS03475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EFD73_RS03485	COG0523	cobalamin synthesis protein
EFD73_RS03490	COG4989	oxidoreductase activity
EFD73_RS03500	COG0471	metal ion transport
EFD73_RS03505	COG0415	Belongs to the DNA photolyase family
EFD73_RS03535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EFD73_RS03540	COG1349	DNA-binding transcription factor activity
EFD73_RS03545	COG1105	Belongs to the carbohydrate kinase PfkB family
EFD73_RS03550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD73_RS03550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD73_RS03550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD73_RS03555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EFD73_RS03560	COG1253	flavin adenine dinucleotide binding
EFD73_RS03565	COG0656	L-ascorbic acid biosynthetic process
EFD73_RS03570	COG0463	Glycosyl transferase, family 2
EFD73_RS03605	COG0720	synthase
EFD73_RS03615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EFD73_RS03615	COG0512	Glutamine amidotransferase of anthranilate synthase
EFD73_RS03620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EFD73_RS03650	COG0488	(ABC) transporter
EFD73_RS03655	COG0514	ATP-dependent DNA helicase (RecQ)
EFD73_RS03660	COG1125	glycine betaine transport
EFD73_RS03660	COG0517	IMP dehydrogenase activity
EFD73_RS03665	COG1174	glycine betaine transport
EFD73_RS03690	COG3104	oligopeptide transport
EFD73_RS03710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFD73_RS03715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFD73_RS03725	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD73_RS03730	COG4605	iron ion homeostasis
EFD73_RS03735	COG4604	ABC transporter, ATP-binding protein
EFD73_RS03740	COG4607	ABC-type enterochelin transport system periplasmic component
EFD73_RS03795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EFD73_RS03800	COG1739	Uncharacterized protein family UPF0029
EFD73_RS03810	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EFD73_RS03815	COG1040	competence protein
EFD73_RS03845	COG1388	LysM domain
EFD73_RS03845	COG3942	CHAP domain
EFD73_RS03900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EFD73_RS03960	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EFD73_RS03965	COG1647	Serine aminopeptidase, S33
EFD73_RS03970	COG0557	exoribonuclease II activity
EFD73_RS04040	COG1278	Cold shock
EFD73_RS04080	COG0406	alpha-ribazole phosphatase activity
EFD73_RS04085	COG1279	arginine transmembrane transporter activity
EFD73_RS04110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EFD73_RS04115	COG1393	Belongs to the ArsC family
EFD73_RS04130	COG3878	Protein conserved in bacteria
EFD73_RS04135	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EFD73_RS04150	COG2011	ABC-type metal ion transport system permease component
EFD73_RS04155	COG1464	Belongs to the NlpA lipoprotein family
EFD73_RS04170	COG0396	ATPase activity
EFD73_RS04175	COG0719	Fe-S assembly protein
EFD73_RS04185	COG0822	iron-sulfur transferase activity
EFD73_RS04205	COG1253	flavin adenine dinucleotide binding
EFD73_RS04220	COG1801	Protein of unknown function DUF72
EFD73_RS04225	COG0730	response to heat
EFD73_RS04240	COG4470	Protein conserved in bacteria
EFD73_RS04255	COG2445	Protein of unknown function DUF86
EFD73_RS04285	COG1696	Membrane protein involved in D-alanine export
EFD73_RS04295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EFD73_RS04300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EFD73_RS04305	COG4837	Protein of unknown function (DUF1462)
EFD73_RS04310	COG1252	NADH dehydrogenase
EFD73_RS04320	COG0316	Belongs to the HesB IscA family
EFD73_RS04330	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EFD73_RS04335	COG2056	Na+-H+ antiporter family
EFD73_RS04340	COG2050	protein possibly involved in aromatic compounds catabolism
EFD73_RS04395	COG1098	S1 RNA binding domain
EFD73_RS04400	COG1902	pentaerythritol trinitrate reductase activity
EFD73_RS04415	COG0584	glycerophosphoryl diester phosphodiesterase
EFD73_RS04435	COG0398	Pfam SNARE associated Golgi protein
EFD73_RS04475	COG0561	phosphatase activity
EFD73_RS04500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EFD73_RS04515	COG1881	PFAM PEBP family protein
EFD73_RS04545	COG0601	transmembrane transport
EFD73_RS04550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFD73_RS04555	COG0444	Belongs to the ABC transporter superfamily
EFD73_RS04560	COG4608	Belongs to the ABC transporter superfamily
EFD73_RS04565	COG4166	transmembrane transport
EFD73_RS04570	COG0747	negative chemotaxis
EFD73_RS04575	COG0444	Belongs to the ABC transporter superfamily
EFD73_RS04580	COG4608	Belongs to the ABC transporter superfamily
EFD73_RS04585	COG0601	transmembrane transport
EFD73_RS04590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFD73_RS04615	COG1164	Oligoendopeptidase f
EFD73_RS04625	COG2346	COG2346, Truncated hemoglobins
EFD73_RS04640	COG2357	RelA SpoT domain protein
EFD73_RS04650	COG0564	pseudouridine synthase activity
EFD73_RS04655	COG2239	Acts as a magnesium transporter
EFD73_RS04660	COG0475	glutathione-regulated potassium exporter activity
EFD73_RS04660	COG0569	domain protein
EFD73_RS04670	COG0628	permease
EFD73_RS04675	COG1115	amino acid carrier protein
EFD73_RS04715	COG0861	Integral membrane protein TerC family
EFD73_RS04725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EFD73_RS04730	COG0737	Belongs to the 5'-nucleotidase family
EFD73_RS04745	COG4903	ComK protein
EFD73_RS04760	COG4873	Protein conserved in bacteria
EFD73_RS04815	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EFD73_RS04825	COG2314	TM2 domain
EFD73_RS04830	COG0456	acetyltransferase
EFD73_RS04835	COG1575	Belongs to the MenA family. Type 1 subfamily
EFD73_RS04845	COG1169	isochorismate synthase
EFD73_RS04855	COG2267	carboxylic ester hydrolase activity
EFD73_RS04880	COG0436	Aminotransferase
EFD73_RS04885	COG3594	Acyltransferase
EFD73_RS04915	COG1316	TRANSCRIPTIONal
EFD73_RS04960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EFD73_RS04975	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFD73_RS05015	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFD73_RS05020	COG4172	Belongs to the ABC transporter superfamily
EFD73_RS05025	COG4721	ABC-type cobalt transport system, permease component
EFD73_RS05045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EFD73_RS05065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EFD73_RS05070	COG1271	oxidase subunit
EFD73_RS05075	COG1294	oxidase, subunit
EFD73_RS05080	COG0569	domain protein
EFD73_RS05145	COG1176	ABC-type spermidine putrescine transport system, permease component I
EFD73_RS05150	COG1177	transmembrane transport
EFD73_RS05155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EFD73_RS05180	COG0483	inositol monophosphate 1-phosphatase activity
EFD73_RS05190	COG1217	gtp-binding protein TYPA
EFD73_RS05200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EFD73_RS05210	COG0772	Belongs to the SEDS family
EFD73_RS05240	COG3679	Belongs to the UPF0342 family
EFD73_RS05260	COG0742	ribosomal rna small subunit methyltransferase
EFD73_RS05330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFD73_RS05360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EFD73_RS05360	COG1796	DNA polymerase
EFD73_RS05385	COG2009	succinate dehydrogenase
EFD73_RS05390	COG1053	succinate dehydrogenase
EFD73_RS05395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EFD73_RS05505	COG1288	antiporter activity
EFD73_RS05540	COG1011	Hydrolase
EFD73_RS05565	COG4839	cell division protein FtsL
EFD73_RS05570	COG0768	penicillin binding
EFD73_RS05585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EFD73_RS05590	COG0849	cell division
EFD73_RS05605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EFD73_RS05615	COG0762	integral membrane protein
EFD73_RS05625	COG3599	regulation of cell shape
EFD73_RS05635	COG2514	catechol 2,3-dioxygenase activity
EFD73_RS05650	COG0564	pseudouridine synthase activity
EFD73_RS05660	COG2233	PERMEase
EFD73_RS05705	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EFD73_RS05720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EFD73_RS05725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFD73_RS05735	COG2314	TM2 domain
EFD73_RS05750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EFD73_RS05750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EFD73_RS05760	COG0631	protein serine/threonine phosphatase activity
EFD73_RS05775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EFD73_RS05790	COG1302	Protein conserved in bacteria
EFD73_RS05835	COG1196	nuclear chromosome segregation
EFD73_RS05840	COG0552	protein localization to endoplasmic reticulum
EFD73_RS05850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EFD73_RS05905	COG2348	transferase activity, transferring amino-acyl groups
EFD73_RS06005	COG0195	Participates in both transcription termination and antitermination
EFD73_RS06010	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EFD73_RS06035	COG0196	riboflavin kinase activity
EFD73_RS06060	COG2188	Transcriptional regulator
EFD73_RS06065	COG0612	Peptidase, M16
EFD73_RS06070	COG0612	Peptidase, M16
EFD73_RS06075	COG0300	oxidoreductase activity
EFD73_RS06095	COG1546	Belongs to the CinA family
EFD73_RS06095	COG1058	Belongs to the CinA family
EFD73_RS06115	COG1692	metallophosphoesterase
EFD73_RS06120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EFD73_RS06120	COG0674	pyruvate-flavodoxin oxidoreductase activity
EFD73_RS06125	COG1013	pyruvate-flavodoxin oxidoreductase activity
EFD73_RS06160	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EFD73_RS06165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EFD73_RS06190	COG1923	regulation of RNA biosynthetic process
EFD73_RS06200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EFD73_RS06205	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EFD73_RS06210	COG0789	Transcriptional regulator
EFD73_RS06290	COG1131	(ABC) transporter
EFD73_RS06305	COG2197	response regulator
EFD73_RS06315	COG1525	nuclease
EFD73_RS06330	COG0527	aspartate kinase activity
EFD73_RS06335	COG0460	homoserine dehydrogenase
EFD73_RS06340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EFD73_RS06365	COG0833	amino acid
EFD73_RS06395	COG2340	Cysteine-rich secretory protein family
EFD73_RS06430	COG4846	Membrane protein involved in cytochrome C biogenesis
EFD73_RS06450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EFD73_RS06460	COG0824	Thioesterase
EFD73_RS06485	COG1115	amino acid carrier protein
EFD73_RS06500	COG0628	permease
EFD73_RS06525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFD73_RS06535	COG1363	Peptidase, m42
EFD73_RS06540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EFD73_RS06545	COG0512	Glutamine amidotransferase of anthranilate synthase
EFD73_RS06590	COG0561	phosphatase activity
EFD73_RS06635	COG0704	Plays a role in the regulation of phosphate uptake
EFD73_RS06645	COG0581	inorganic phosphate transmembrane transporter activity
EFD73_RS06650	COG0573	inorganic phosphate transmembrane transporter activity
EFD73_RS06670	COG0488	(ABC) transporter
EFD73_RS06675	COG0527	aspartate kinase activity
EFD73_RS06680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EFD73_RS06750	COG4548	von Willebrand factor, type A
EFD73_RS06755	COG0714	Associated with various cellular activities
EFD73_RS06800	COG0671	phosphoesterase, PA-phosphatase related
EFD73_RS06875	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EFD73_RS06895	COG0531	amino acid
EFD73_RS06910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFD73_RS06915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EFD73_RS06930	COG0116	Belongs to the methyltransferase superfamily
EFD73_RS06965	COG4499	WXG100 protein secretion system (Wss), protein YukC
EFD73_RS06965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EFD73_RS06975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EFD73_RS06980	COG3935	DnaD domain protein
EFD73_RS07005	COG0438	transferase activity, transferring glycosyl groups
EFD73_RS07010	COG1694	Mazg nucleotide pyrophosphohydrolase
EFD73_RS07015	COG2738	Putative neutral zinc metallopeptidase
EFD73_RS07020	COG4347	Protein of unknown function (DUF1405)
EFD73_RS07060	COG0142	geranyltranstransferase activity
EFD73_RS07115	COG0492	ferredoxin-NADP+ reductase activity
EFD73_RS07130	COG0514	ATP-dependent DNA helicase (RecQ)
EFD73_RS07140	COG1141	Ferredoxin
EFD73_RS07175	COG1388	LysM domain
EFD73_RS07175	COG0860	N-Acetylmuramoyl-L-alanine amidase
EFD73_RS07225	COG3953	SLT domain
EFD73_RS07225	COG5280	Phage tail tape measure protein TP901
EFD73_RS07490	COG0582	viral genome integration into host DNA
EFD73_RS07510	COG0745	RESPONSE REGULATOR receiver
EFD73_RS07515	COG1187	pseudouridine synthase activity
EFD73_RS07540	COG0735	belongs to the Fur family
EFD73_RS07545	COG0494	nUDIX hydrolase
EFD73_RS07550	COG0667	Aldo Keto reductase
EFD73_RS07560	COG4221	oxidoreductase activity
EFD73_RS07575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EFD73_RS07585	COG0366	Alpha amylase catalytic
EFD73_RS07590	COG1609	Transcriptional regulator
EFD73_RS07615	COG2195	Cleaves the N-terminal amino acid of tripeptides
EFD73_RS07625	COG4129	membrane
EFD73_RS07635	COG0508	dehydrogenase complex catalyzes the overall conversion of
EFD73_RS07640	COG0022	dehydrogenase e1 component
EFD73_RS07645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EFD73_RS07650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EFD73_RS07655	COG0497	DNA recombination
EFD73_RS07685	COG1302	Protein conserved in bacteria
EFD73_RS07690	COG0439	Biotin carboxylase
EFD73_RS07695	COG0511	ligase activity, forming carbon-carbon bonds
EFD73_RS07705	COG0006	proline dipeptidase activity
EFD73_RS07720	COG0095	Lipoate-protein ligase
EFD73_RS07725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFD73_RS07770	COG4537	Required for transformation and DNA binding
EFD73_RS07775	COG1459	type II secretion system
EFD73_RS07780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EFD73_RS07785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EFD73_RS07790	COG0011	TIGRFAM Protein of
EFD73_RS07795	COG1940	carbohydrate kinase activity
EFD73_RS07800	COG4483	Protein conserved in bacteria
EFD73_RS07810	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EFD73_RS07820	COG0768	penicillin binding
EFD73_RS07835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EFD73_RS07840	COG1121	(ABC) transporter
EFD73_RS07850	COG0513	Belongs to the DEAD box helicase family
EFD73_RS07860	COG2384	SAM-dependent methyltransferase
EFD73_RS07880	COG0517	IMP dehydrogenase activity
EFD73_RS07900	COG0295	cytidine deaminase activity
EFD73_RS07915	COG1702	phosphate starvation-inducible protein PhoH
EFD73_RS07930	COG1030	water channel activity
EFD73_RS07945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EFD73_RS07950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EFD73_RS07980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EFD73_RS07995	COG1466	dna polymerase III delta subunit
EFD73_RS08000	COG0658	competence protein
EFD73_RS08000	COG2333	competence protein COMEC
EFD73_RS08005	COG2131	deaminase
EFD73_RS08010	COG2183	response to ionizing radiation
EFD73_RS08015	COG2226	methyltransferase
EFD73_RS08020	COG0799	negative regulation of ribosome biogenesis
EFD73_RS08025	COG1713	HD superfamily hydrolase involved in NAD metabolism
EFD73_RS08035	COG1534	Rna-binding protein
EFD73_RS08045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EFD73_RS08050	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EFD73_RS08070	COG3177	Filamentation induced by cAMP protein fic
EFD73_RS08075	COG1914	H( )-stimulated, divalent metal cation uptake system
EFD73_RS08085	COG0439	Biotin carboxylase
EFD73_RS08090	COG0511	ligase activity, forming carbon-carbon bonds
EFD73_RS08095	COG1984	allophanate hydrolase subunit 2
EFD73_RS08100	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EFD73_RS08115	COG0826	peptidase U32
EFD73_RS08120	COG0826	peptidase U32
EFD73_RS08150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EFD73_RS08165	COG1104	cysteine desulfurase activity
EFD73_RS08170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFD73_RS08180	COG3237	CsbD-like
EFD73_RS08185	COG1959	2 iron, 2 sulfur cluster binding
EFD73_RS08190	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EFD73_RS08195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EFD73_RS08240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EFD73_RS08240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EFD73_RS08245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EFD73_RS08245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EFD73_RS08250	COG1862	Preprotein translocase
EFD73_RS08290	COG2868	ribosomal protein
EFD73_RS08335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EFD73_RS08375	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EFD73_RS08380	COG0285	dihydrofolate synthase activity
EFD73_RS08390	COG2818	Glycosylase
EFD73_RS08425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EFD73_RS08460	COG4112	unkown
EFD73_RS08480	COG0833	amino acid
EFD73_RS08495	COG1484	DNA-dependent DNA replication
EFD73_RS08525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFD73_RS08525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFD73_RS08535	COG5002	protein histidine kinase activity
EFD73_RS08540	COG0745	RESPONSE REGULATOR receiver
EFD73_RS08550	COG0372	Belongs to the citrate synthase family
EFD73_RS08555	COG1113	amino acid transport
EFD73_RS08580	COG0281	malic enzyme
EFD73_RS08590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EFD73_RS08595	COG4109	DRTGG domain
EFD73_RS08635	COG0827	DNA restriction-modification system
EFD73_RS08645	COG0730	response to heat
EFD73_RS08655	COG1104	cysteine desulfurase activity
EFD73_RS08670	COG1956	GAF domain-containing protein
EFD73_RS08685	COG0584	glycerophosphoryl diester phosphodiesterase
EFD73_RS08690	COG1764	response to oxidative stress
EFD73_RS08695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EFD73_RS08700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EFD73_RS08715	COG1263	PTS System
EFD73_RS08715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD73_RS08720	COG0204	Acyl-transferase
EFD73_RS08725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFD73_RS08760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EFD73_RS08765	COG0454	-acetyltransferase
EFD73_RS08785	COG1605	Chorismate mutase
EFD73_RS08785	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EFD73_RS08810	COG1674	ftsk spoiiie
EFD73_RS08815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFD73_RS08825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EFD73_RS08830	COG1363	Peptidase, m42
EFD73_RS08840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EFD73_RS08850	COG0510	thiamine kinase activity
EFD73_RS08870	COG1187	pseudouridine synthase activity
EFD73_RS08875	COG2244	polysaccharide biosynthetic process
EFD73_RS08880	COG2081	HI0933 family
EFD73_RS08900	COG2814	Major facilitator Superfamily
EFD73_RS08905	COG1242	4 iron, 4 sulfur cluster binding
EFD73_RS08910	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EFD73_RS08920	COG2267	carboxylic ester hydrolase activity
EFD73_RS08950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EFD73_RS08950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EFD73_RS08970	COG3266	domain, Protein
EFD73_RS08970	COG4193	domain, Protein
EFD73_RS08970	COG5632	N-Acetylmuramoyl-L-alanine amidase
EFD73_RS09000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EFD73_RS09025	COG0656	L-ascorbic acid biosynthetic process
EFD73_RS09045	COG1506	peptidase
EFD73_RS09050	COG2816	NAD+ diphosphatase activity
EFD73_RS09285	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EFD73_RS09315	COG1131	(ABC) transporter
EFD73_RS09320	COG0537	adenosine 5'-monophosphoramidase activity
EFD73_RS09350	COG0420	3'-5' exonuclease activity
EFD73_RS09375	COG2197	response regulator
EFD73_RS09380	COG4585	Histidine kinase
EFD73_RS09380	COG2203	Gaf domain
EFD73_RS09385	COG0564	pseudouridine synthase activity
EFD73_RS09415	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EFD73_RS09420	COG1126	abc transporter atp-binding protein
EFD73_RS09425	COG0765	amino acid transport
EFD73_RS09600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EFD73_RS09605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EFD73_RS09615	COG4129	membrane
EFD73_RS09640	COG1988	membrane-bound metal-dependent
EFD73_RS09650	COG1388	LysM domain
EFD73_RS09650	COG1134	teichoic acid transport
EFD73_RS09680	COG0535	radical SAM domain protein
EFD73_RS09685	COG1607	acyl-coa hydrolase
EFD73_RS09690	COG2309	aminopeptidase activity
EFD73_RS09710	COG1295	ribonuclease BN
EFD73_RS09825	COG4851	CamS sex pheromone cAM373 precursor
EFD73_RS09845	COG4496	protein, YerC YecD
EFD73_RS09880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EFD73_RS09890	COG0077	Prephenate dehydratase
EFD73_RS09900	COG0471	metal ion transport
EFD73_RS09910	COG1335	isochorismatase
EFD73_RS09925	COG1012	belongs to the aldehyde dehydrogenase family
EFD73_RS09980	COG1131	(ABC) transporter
EFD73_RS09995	COG1725	Transcriptional regulator
EFD73_RS10060	COG1388	LysM domain
EFD73_RS10060	COG5632	N-Acetylmuramoyl-L-alanine amidase
EFD73_RS10110	COG0739	heme binding
EFD73_RS10160	COG0740	serine-type endopeptidase activity
EFD73_RS10330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EFD73_RS10385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EFD73_RS10450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EFD73_RS10455	COG1621	beta-fructofuranosidase activity
EFD73_RS10460	COG1609	Transcriptional regulator
EFD73_RS10465	COG0004	ammonium transporteR
EFD73_RS10470	COG0425	Belongs to the sulfur carrier protein TusA family
EFD73_RS10475	COG2391	methyltransferase activity
EFD73_RS10485	COG0488	(ABC) transporter
EFD73_RS10495	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EFD73_RS10510	COG1214	PFAM Peptidase M22, glycoprotease
EFD73_RS10515	COG0802	atpase or kinase
EFD73_RS10530	COG0028	Belongs to the TPP enzyme family
EFD73_RS10605	COG2183	response to ionizing radiation
EFD73_RS10610	COG1191	sigma factor activity
EFD73_RS10620	COG1366	Belongs to the anti-sigma-factor antagonist family
EFD73_RS10625	COG2208	phosphoserine phosphatase activity
EFD73_RS10655	COG3428	Bacterial PH domain
EFD73_RS10685	COG2205	protein histidine kinase activity
EFD73_RS10690	COG0745	RESPONSE REGULATOR receiver
EFD73_RS10705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EFD73_RS10715	COG0772	Belongs to the SEDS family
EFD73_RS10730	COG1937	Protein conserved in bacteria
EFD73_RS10740	COG1418	mRNA catabolic process
EFD73_RS10785	COG0629	single-stranded DNA binding
EFD73_RS10860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EFD73_RS10885	COG0009	L-threonylcarbamoyladenylate synthase
EFD73_RS10890	COG2890	protein-(glutamine-N5) methyltransferase activity
EFD73_RS10910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EFD73_RS10950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EFD73_RS10995	COG0813	purine-nucleoside phosphorylase activity
EFD73_RS11000	COG0783	Belongs to the Dps family
EFD73_RS11020	COG1482	cell wall glycoprotein biosynthetic process
EFD73_RS11025	COG0702	epimerase
EFD73_RS11030	COG0640	Transcriptional regulator
EFD73_RS11060	COG0561	phosphatase activity
EFD73_RS11065	COG1119	ATPase activity
EFD73_RS11080	COG3711	transcriptional antiterminator
EFD73_RS11110	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFD73_RS11170	COG0489	protein tyrosine kinase activity
EFD73_RS11175	COG2814	Major facilitator Superfamily
EFD73_RS11190	COG1272	protein, Hemolysin III
EFD73_RS11200	COG1988	membrane-bound metal-dependent
EFD73_RS11210	COG3314	Sporulation integral membrane protein YlbJ
EFD73_RS11215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD73_RS11220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD73_RS11225	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EFD73_RS11235	COG3457	Alanine racemase
EFD73_RS11240	COG4264	IucA IucC family
EFD73_RS11245	COG2814	Major facilitator Superfamily
EFD73_RS11270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EFD73_RS11280	COG2130	NADP-dependent
EFD73_RS11345	COG0656	L-ascorbic acid biosynthetic process
EFD73_RS11350	COG0789	Transcriptional regulator
EFD73_RS11360	COG5492	domain, Protein
EFD73_RS11380	COG3527	Alpha-acetolactate decarboxylase
EFD73_RS11385	COG0028	Belongs to the TPP enzyme family
EFD73_RS11500	COG0201	protein transport
EFD73_RS11615	COG2252	PERMEase
EFD73_RS11660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EFD73_RS11720	COG1763	Mo-molybdopterin cofactor biosynthetic process
EFD73_RS11740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EFD73_RS11745	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EFD73_RS11750	COG4149	molybdate abc transporter
EFD73_RS11755	COG0725	ABC transporter, periplasmic molybdate-binding protein
EFD73_RS11770	COG1268	BioY protein
EFD73_RS11785	COG1960	acyl-CoA dehydrogenase activity
EFD73_RS11790	COG4413	Urea transporter
EFD73_RS11850	COG3942	CHAP domain
EFD73_RS11860	COG1757	Na H antiporter
EFD73_RS11875	COG3942	CHAP domain
EFD73_RS11940	COG1113	amino acid transport
EFD73_RS11960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EFD73_RS11965	COG0385	Bile acid
EFD73_RS11975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD73_RS11975	COG1263	PTS System
EFD73_RS11980	COG1737	Transcriptional regulator
EFD73_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
EFD73_RS12005	COG1473	amidohydrolase
EFD73_RS12020	COG0583	DNA-binding transcription factor activity
EFD73_RS12045	COG2258	MOSC domain
EFD73_RS12065	COG1668	transmembrane transport
EFD73_RS12070	COG4152	abc transporter atp-binding protein
EFD73_RS12075	COG3152	Membrane
EFD73_RS12085	COG0786	glutamate:sodium symporter activity
EFD73_RS12095	COG0598	Magnesium transport protein CorA
EFD73_RS12110	COG0657	acetylesterase activity
EFD73_RS12120	COG2814	Major facilitator Superfamily
EFD73_RS12125	COG1566	PFAM secretion protein HlyD family protein
EFD73_RS12195	COG1620	l-lactate permease
EFD73_RS12215	COG0604	alcohol dehydrogenase
EFD73_RS12240	COG1511	domain protein
EFD73_RS12255	COG1263	PTS System
EFD73_RS12255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD73_RS12270	COG3871	stress protein (general stress protein 26)
EFD73_RS12310	COG0789	Transcriptional regulator
EFD73_RS12330	COG2181	nitrate reductase activity
EFD73_RS12340	COG1140	nitrate reductase beta subunit
EFD73_RS12345	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFD73_RS12355	COG2146	nitrite reductase [NAD(P)H] activity
EFD73_RS12360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EFD73_RS12370	COG0454	-acetyltransferase
EFD73_RS12375	COG2116	formate transmembrane transporter activity
EFD73_RS12390	COG3443	Belongs to the bacterial solute-binding protein 9 family
EFD73_RS12390	COG0803	Belongs to the bacterial solute-binding protein 9 family
EFD73_RS12430	COG1126	abc transporter atp-binding protein
EFD73_RS12435	COG0765	amino acid transport
EFD73_RS12440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EFD73_RS12445	COG2814	Major facilitator Superfamily
EFD73_RS12460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFD73_RS12500	COG0156	8-amino-7-oxononanoate synthase activity
EFD73_RS12510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EFD73_RS12515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EFD73_RS12525	COG1132	(ABC) transporter
EFD73_RS12530	COG2375	cellular response to nickel ion
EFD73_RS12530	COG1132	(ABC) transporter
EFD73_RS12545	COG1929	Belongs to the glycerate kinase type-1 family
EFD73_RS12555	COG2814	Major facilitator Superfamily
EFD73_RS12575	COG1113	amino acid transport
EFD73_RS12585	COG0531	amino acid
EFD73_RS12600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFD73_RS12610	COG1174	glycine betaine transport
EFD73_RS12620	COG1174	glycine betaine transport
EFD73_RS12640	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EFD73_RS12645	COG0531	amino acid
EFD73_RS12650	COG2272	Belongs to the type-B carboxylesterase lipase family
EFD73_RS12655	COG2814	Major facilitator Superfamily
EFD73_RS12660	COG0390	transport system, permease component
EFD73_RS12665	COG4619	ABC transporter
EFD73_RS12670	COG1363	Peptidase, m42
EFD73_RS12685	COG4808	Protein conserved in bacteria
EFD73_RS12690	COG0069	glutamate synthase activity
EFD73_RS12745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EFD73_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
EFD73_RS12755	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EFD73_RS12760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EFD73_RS12850	COG0494	nUDIX hydrolase
EFD73_RS12890	COG1846	Transcriptional regulator
EFD73_RS12925	COG1070	Carbohydrate kinase
EFD73_RS12930	COG1802	Transcriptional regulator
EFD73_RS12935	COG0789	Transcriptional regulator
EFD73_RS12940	COG2357	RelA SpoT domain protein
EFD73_RS12945	COG4876	unkown
EFD73_RS12955	COG2271	Major facilitator Superfamily
EFD73_RS12960	COG0586	Pfam SNARE associated Golgi protein
EFD73_RS12970	COG1131	(ABC) transporter
EFD73_RS12990	COG0400	carboxylic ester hydrolase activity
EFD73_RS12995	COG0346	lactoylglutathione lyase activity
EFD73_RS13000	COG1846	Transcriptional regulator
EFD73_RS13010	COG2514	catechol 2,3-dioxygenase activity
EFD73_RS13025	COG0561	phosphatase activity
EFD73_RS13030	COG1131	(ABC) transporter
EFD73_RS13040	COG3764	Sortase (surface protein transpeptidase)
EFD73_RS13060	COG1760	l-serine dehydratase
EFD73_RS13065	COG1760	l-serine dehydratase
EFD73_RS13080	COG0697	spore germination
EFD73_RS13085	COG0657	acetylesterase activity
EFD73_RS13105	COG0028	Belongs to the TPP enzyme family
EFD73_RS13120	COG0583	DNA-binding transcription factor activity
EFD73_RS13130	COG3942	CHAP domain
EFD73_RS13140	COG3425	synthase
EFD73_RS13145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EFD73_RS13170	COG2409	Drug exporters of the RND superfamily
EFD73_RS13215	COG0436	Aminotransferase
EFD73_RS13245	COG3942	CHAP domain
EFD73_RS13250	COG2755	lipolytic protein G-D-S-L family
EFD73_RS13250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EFD73_RS13355	COG3001	Fructosamine kinase
EFD73_RS13360	COG0167	dihydroorotate dehydrogenase activity
EFD73_RS13415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFD73_RS13420	COG3527	Alpha-acetolactate decarboxylase
EFD73_RS13430	COG0531	amino acid
EFD73_RS13460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EFD73_RS13480	COG1012	belongs to the aldehyde dehydrogenase family
EFD73_RS13490	COG1510	regulation of RNA biosynthetic process
EFD73_RS13495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EFD73_RS13520	COG2851	Citrate transporter
EFD73_RS13535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EFD73_RS13545	COG0386	Belongs to the glutathione peroxidase family
EFD73_RS13565	COG1136	(ABC) transporter
EFD73_RS13570	COG2205	protein histidine kinase activity
EFD73_RS13575	COG0745	RESPONSE REGULATOR receiver
EFD73_RS13585	COG1785	Belongs to the alkaline phosphatase family
EFD73_RS13595	COG1846	Transcriptional regulator
EFD73_RS13640	COG1438	arginine binding
EFD73_RS13660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD73_RS13660	COG3711	transcriptional antiterminator
EFD73_RS13665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD73_RS13665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD73_RS13665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD73_RS13670	COG1482	cell wall glycoprotein biosynthetic process
EFD73_RS13680	COG3942	CHAP domain
EFD73_RS13680	COG1705	Flagellar rod assembly protein muramidase FlgJ
EFD73_RS13685	COG3433	isochorismatase activity
EFD73_RS13685	COG1535	isochorismatase
EFD73_RS13700	COG0438	transferase activity, transferring glycosyl groups
EFD73_RS13715	COG1073	alpha beta
EFD73_RS13735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EFD73_RS13755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EFD73_RS13845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EFD73_RS13930	COG0471	metal ion transport
EFD73_RS13935	COG2962	Rard protein
EFD73_RS13945	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EFD73_RS13960	COG1136	(ABC) transporter
EFD73_RS13965	COG0577	efflux transmembrane transporter activity
EFD73_RS13975	COG1278	Cold shock
EFD73_RS13995	COG1475	DNA binding