locus-tag	class	description
BRL61_RS00015	COG2501	S4 domain
BRL61_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BRL61_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRL61_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BRL61_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
BRL61_RS00120	COG4863	YycH protein
BRL61_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BRL61_RS00135	COG0737	Belongs to the 5'-nucleotidase family
BRL61_RS00150	COG1388	LysM domain
BRL61_RS00155	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRL61_RS00165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BRL61_RS00205	COG2217	Heavy metal translocating P-type atpase
BRL61_RS00220	COG3655	Transcriptional regulator
BRL61_RS00225	COG2311	Membrane
BRL61_RS00245	COG1401	restriction endodeoxyribonuclease activity
BRL61_RS00250	COG4268	DNA restriction-modification system
BRL61_RS00270	COG2814	Major facilitator Superfamily
BRL61_RS00295	COG0456	acetyltransferase
BRL61_RS00325	COG0823	Involved in the tonB-independent uptake of proteins
BRL61_RS00340	COG1473	amidohydrolase
BRL61_RS00350	COG1283	sodium-dependent phosphate transmembrane transporter activity
BRL61_RS00355	COG4716	Myosin-crossreactive antigen
BRL61_RS00365	COG1620	l-lactate permease
BRL61_RS00385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL61_RS00390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL61_RS00395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL61_RS00405	COG2423	ornithine cyclodeaminase activity
BRL61_RS00410	COG4264	IucA IucC family
BRL61_RS00415	COG2814	Major facilitator Superfamily
BRL61_RS00420	COG4264	IucA IucC family
BRL61_RS00425	COG4264	IucA IucC family
BRL61_RS00435	COG0019	diaminopimelate decarboxylase activity
BRL61_RS00440	COG1475	DNA binding
BRL61_RS00465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRL61_RS00470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BRL61_RS00475	COG0438	transferase activity, transferring glycosyl groups
BRL61_RS00510	COG0813	purine-nucleoside phosphorylase activity
BRL61_RS00515	COG2814	Major facilitator Superfamily
BRL61_RS00535	COG3639	organic phosphonate transmembrane transporter activity
BRL61_RS00555	COG0737	Belongs to the 5'-nucleotidase family
BRL61_RS00570	COG1454	alcohol dehydrogenase
BRL61_RS00570	COG1012	belongs to the aldehyde dehydrogenase family
BRL61_RS00595	COG1086	Polysaccharide biosynthesis protein
BRL61_RS00605	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BRL61_RS00635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BRL61_RS00645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BRL61_RS00650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BRL61_RS00660	COG2832	Protein of unknown function (DUF454)
BRL61_RS00695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRL61_RS00700	COG1960	acyl-CoA dehydrogenase activity
BRL61_RS00705	COG5609	conserved protein (DUF2294)
BRL61_RS00755	COG1114	Component of the transport system for branched-chain amino acids
BRL61_RS00760	COG1335	isochorismatase
BRL61_RS00765	COG3961	Belongs to the TPP enzyme family
BRL61_RS00795	COG1737	Transcriptional regulator
BRL61_RS00820	COG0601	transmembrane transport
BRL61_RS00825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRL61_RS00835	COG0405	Gamma-glutamyltransferase
BRL61_RS00850	COG3842	ATPase activity
BRL61_RS00860	COG1175	transmembrane transport
BRL61_RS00865	COG3833	ABC-type maltose transport systems, permease component
BRL61_RS00870	COG0673	inositol 2-dehydrogenase activity
BRL61_RS00875	COG0673	inositol 2-dehydrogenase activity
BRL61_RS00885	COG1755	Isoprenylcysteine carboxyl methyltransferase
BRL61_RS00940	COG0183	Belongs to the thiolase family
BRL61_RS00950	COG1960	acyl-CoA dehydrogenase activity
BRL61_RS00955	COG0318	PFAM AMP-dependent synthetase and ligase
BRL61_RS00975	COG0747	negative chemotaxis
BRL61_RS00980	COG3189	MarR family transcriptional regulator
BRL61_RS01015	COG2190	(PTS) system
BRL61_RS01015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL61_RS01015	COG1263	PTS System
BRL61_RS01020	COG1957	nucleoside hydrolase
BRL61_RS01040	COG3414	Phosphotransferase system galactitol-specific IIB component
BRL61_RS01045	COG3775	system Galactitol-specific IIC component
BRL61_RS01050	COG1063	alcohol dehydrogenase
BRL61_RS01060	COG1063	alcohol dehydrogenase
BRL61_RS01070	COG1063	alcohol dehydrogenase
BRL61_RS01075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BRL61_RS01080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BRL61_RS01090	COG1063	alcohol dehydrogenase
BRL61_RS01095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BRL61_RS01135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRL61_RS01145	COG1263	PTS System
BRL61_RS01145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL61_RS01145	COG2190	(PTS) system
BRL61_RS01150	COG2723	6-phospho-beta-galactosidase activity
BRL61_RS01160	COG2226	methyltransferase
BRL61_RS01215	COG1131	(ABC) transporter
BRL61_RS01235	COG3942	CHAP domain
BRL61_RS01235	COG1388	LysM domain
BRL61_RS01380	COG1114	Component of the transport system for branched-chain amino acids
BRL61_RS01390	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BRL61_RS01400	COG0577	efflux transmembrane transporter activity
BRL61_RS01430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BRL61_RS01435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRL61_RS01460	COG3314	Sporulation integral membrane protein YlbJ
BRL61_RS01470	COG0582	viral genome integration into host DNA
BRL61_RS01615	COG0756	dUTP diphosphatase activity
BRL61_RS01750	COG5280	Phage tail tape measure protein TP901
BRL61_RS01750	COG3953	SLT domain
BRL61_RS01800	COG1388	LysM domain
BRL61_RS01800	COG5632	N-Acetylmuramoyl-L-alanine amidase
BRL61_RS01830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRL61_RS01860	COG3037	sugar-specific permease SgaT UlaA
BRL61_RS01870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL61_RS01875	COG3711	transcriptional antiterminator
BRL61_RS01900	COG2271	Major facilitator Superfamily
BRL61_RS01905	COG0346	lactoylglutathione lyase activity
BRL61_RS01910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRL61_RS01930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRL61_RS01935	COG2822	iron ion transport
BRL61_RS01945	COG0672	)-iron permease
BRL61_RS01950	COG0805	protein transport
BRL61_RS01955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BRL61_RS01965	COG1476	TRANSCRIPTIONal
BRL61_RS01975	COG1131	(ABC) transporter
BRL61_RS02005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BRL61_RS02005	COG0646	methionine synthase
BRL61_RS02010	COG0626	cystathionine gamma-synthase activity
BRL61_RS02015	COG0626	cystathionine gamma-synthase activity
BRL61_RS02025	COG1475	DNA binding
BRL61_RS02030	COG0668	transmembrane transport
BRL61_RS02035	COG4481	Protein conserved in bacteria
BRL61_RS02040	COG0012	GTP binding
BRL61_RS02080	COG0582	viral genome integration into host DNA
BRL61_RS02145	COG1823	symporter activity
BRL61_RS02185	COG2233	PERMEase
BRL61_RS02230	COG3759	membrane
BRL61_RS02370	COG0523	cobalamin synthesis protein
BRL61_RS02385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BRL61_RS02395	COG5609	conserved protein (DUF2294)
BRL61_RS02410	COG1647	Serine aminopeptidase, S33
BRL61_RS02420	COG0733	neurotransmitter:sodium symporter activity
BRL61_RS02425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BRL61_RS02430	COG0626	cystathionine gamma-synthase activity
BRL61_RS02440	COG2011	ABC-type metal ion transport system permease component
BRL61_RS02445	COG1464	Belongs to the NlpA lipoprotein family
BRL61_RS02480	COG0583	DNA-binding transcription factor activity
BRL61_RS02485	COG0070	glutamate synthase
BRL61_RS02485	COG0067	glutamate synthase
BRL61_RS02485	COG0069	glutamate synthase activity
BRL61_RS02490	COG0493	'glutamate synthase
BRL61_RS02500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL61_RS02500	COG1263	PTS System
BRL61_RS02505	COG0366	Alpha amylase catalytic
BRL61_RS02510	COG2188	Transcriptional regulator
BRL61_RS02530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BRL61_RS02565	COG2801	Transposase and inactivated derivatives
BRL61_RS02580	COG1982	Orn Lys Arg decarboxylase major
BRL61_RS02590	COG3870	Protein conserved in bacteria
BRL61_RS02595	COG0470	DNA polymerase III
BRL61_RS02600	COG1774	PSP1 C-terminal conserved region
BRL61_RS02610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BRL61_RS02620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BRL61_RS02630	COG0084	hydrolase, TatD family'
BRL61_RS02635	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BRL61_RS02645	COG4466	Protein conserved in bacteria
BRL61_RS02655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BRL61_RS02660	COG0251	oxidation-reduction process
BRL61_RS02705	COG2244	polysaccharide biosynthetic process
BRL61_RS02710	COG3956	TIGRFAM MazG family protein
BRL61_RS02715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BRL61_RS02725	COG1098	S1 RNA binding domain
BRL61_RS02740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BRL61_RS02765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BRL61_RS02845	COG2801	Transposase and inactivated derivatives
BRL61_RS02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRL61_RS02875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BRL61_RS02885	COG3880	PFAM UvrB UvrC protein
BRL61_RS02900	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BRL61_RS02905	COG4956	integral membrane protein (PIN domain superfamily)
BRL61_RS02930	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BRL61_RS02985	COG2813	Specifically methylates the guanine in position
BRL61_RS03025	COG1473	amidohydrolase
BRL61_RS03055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BRL61_RS03060	COG1428	Deoxynucleoside kinase
BRL61_RS03065	COG1428	Deoxynucleoside kinase
BRL61_RS03075	COG0561	phosphatase activity
BRL61_RS03120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BRL61_RS03235	COG0095	Lipoate-protein ligase
BRL61_RS03240	COG0083	homoserine kinase activity
BRL61_RS03260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRL61_RS03305	COG0667	Aldo Keto reductase
BRL61_RS03310	COG0655	NAD(P)H dehydrogenase (quinone) activity
BRL61_RS03320	COG1078	dGTPase activity
BRL61_RS03355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL61_RS03360	COG4139	cobalamin transport
BRL61_RS03460	COG2814	Major facilitator Superfamily
BRL61_RS03470	COG0803	Belongs to the bacterial solute-binding protein 9 family
BRL61_RS03475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BRL61_RS03480	COG1121	(ABC) transporter
BRL61_RS03485	COG1321	iron dependent repressor
BRL61_RS03505	COG1682	transport, permease protein
BRL61_RS03510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BRL61_RS03520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BRL61_RS03525	COG1686	Belongs to the peptidase S11 family
BRL61_RS03530	COG1132	(ABC) transporter
BRL61_RS03535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BRL61_RS03545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BRL61_RS03550	COG1120	ATPase activity
BRL61_RS03555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL61_RS03560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL61_RS03565	COG2376	Dihydroxyacetone kinase
BRL61_RS03585	COG3949	Membrane
BRL61_RS03610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRL61_RS03625	COG1136	(ABC) transporter
BRL61_RS03630	COG0577	efflux transmembrane transporter activity
BRL61_RS03635	COG1392	Phosphate transport regulator
BRL61_RS03640	COG0306	phosphate transporter
BRL61_RS03645	COG3942	CHAP domain
BRL61_RS03645	COG1388	LysM domain
BRL61_RS03655	COG1917	Cupin 2, conserved barrel domain protein
BRL61_RS03655	COG4977	sequence-specific DNA binding
BRL61_RS03685	COG0583	DNA-binding transcription factor activity
BRL61_RS03695	COG2814	Major facilitator Superfamily
BRL61_RS03700	COG2839	Protein conserved in bacteria
BRL61_RS03735	COG1611	Belongs to the LOG family
BRL61_RS03755	COG4988	ABC transporter
BRL61_RS03760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BRL61_RS03770	COG0523	cobalamin synthesis protein
BRL61_RS03775	COG4989	oxidoreductase activity
BRL61_RS03785	COG0471	metal ion transport
BRL61_RS03790	COG0415	Belongs to the DNA photolyase family
BRL61_RS03820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BRL61_RS03825	COG1349	DNA-binding transcription factor activity
BRL61_RS03830	COG1105	Belongs to the carbohydrate kinase PfkB family
BRL61_RS03835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL61_RS03835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL61_RS03835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL61_RS03840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BRL61_RS03845	COG1253	flavin adenine dinucleotide binding
BRL61_RS03850	COG0656	L-ascorbic acid biosynthetic process
BRL61_RS03855	COG0463	Glycosyl transferase, family 2
BRL61_RS03890	COG0720	synthase
BRL61_RS03900	COG0512	Glutamine amidotransferase of anthranilate synthase
BRL61_RS03900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BRL61_RS03905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BRL61_RS03935	COG0488	(ABC) transporter
BRL61_RS03940	COG0514	ATP-dependent DNA helicase (RecQ)
BRL61_RS03945	COG0517	IMP dehydrogenase activity
BRL61_RS03945	COG1125	glycine betaine transport
BRL61_RS03950	COG1174	glycine betaine transport
BRL61_RS03980	COG3104	oligopeptide transport
BRL61_RS04010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRL61_RS04015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRL61_RS04025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL61_RS04030	COG4605	iron ion homeostasis
BRL61_RS04035	COG4604	ABC transporter, ATP-binding protein
BRL61_RS04040	COG4607	ABC-type enterochelin transport system periplasmic component
BRL61_RS04100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRL61_RS04105	COG1739	Uncharacterized protein family UPF0029
BRL61_RS04115	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BRL61_RS04120	COG1040	competence protein
BRL61_RS04155	COG3942	CHAP domain
BRL61_RS04155	COG1388	LysM domain
BRL61_RS04215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BRL61_RS04235	COG0281	malic enzyme
BRL61_RS04285	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BRL61_RS04290	COG1647	Serine aminopeptidase, S33
BRL61_RS04295	COG0557	exoribonuclease II activity
BRL61_RS04360	COG1278	Cold shock
BRL61_RS04400	COG0406	alpha-ribazole phosphatase activity
BRL61_RS04405	COG1279	arginine transmembrane transporter activity
BRL61_RS04430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL61_RS04435	COG1393	Belongs to the ArsC family
BRL61_RS04450	COG3878	Protein conserved in bacteria
BRL61_RS04480	COG0488	(ABC) transporter
BRL61_RS04490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BRL61_RS04505	COG2011	ABC-type metal ion transport system permease component
BRL61_RS04510	COG1464	Belongs to the NlpA lipoprotein family
BRL61_RS04540	COG0396	ATPase activity
BRL61_RS04545	COG0719	Fe-S assembly protein
BRL61_RS04555	COG0822	iron-sulfur transferase activity
BRL61_RS04575	COG1253	flavin adenine dinucleotide binding
BRL61_RS04585	COG1801	Protein of unknown function DUF72
BRL61_RS04590	COG0730	response to heat
BRL61_RS04605	COG4470	Protein conserved in bacteria
BRL61_RS04615	COG2445	Protein of unknown function DUF86
BRL61_RS04645	COG1696	Membrane protein involved in D-alanine export
BRL61_RS04655	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BRL61_RS04660	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BRL61_RS04665	COG4837	Protein of unknown function (DUF1462)
BRL61_RS04670	COG1252	NADH dehydrogenase
BRL61_RS04680	COG0316	Belongs to the HesB IscA family
BRL61_RS04690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BRL61_RS04695	COG2056	Na+-H+ antiporter family
BRL61_RS04700	COG2050	protein possibly involved in aromatic compounds catabolism
BRL61_RS04755	COG1098	S1 RNA binding domain
BRL61_RS04760	COG1902	pentaerythritol trinitrate reductase activity
BRL61_RS04785	COG0584	glycerophosphoryl diester phosphodiesterase
BRL61_RS04805	COG0398	Pfam SNARE associated Golgi protein
BRL61_RS04850	COG0561	phosphatase activity
BRL61_RS04880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BRL61_RS04895	COG1881	PFAM PEBP family protein
BRL61_RS04925	COG0601	transmembrane transport
BRL61_RS04930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRL61_RS04935	COG0444	Belongs to the ABC transporter superfamily
BRL61_RS04940	COG4608	Belongs to the ABC transporter superfamily
BRL61_RS04945	COG4166	transmembrane transport
BRL61_RS04955	COG2826	transposase and inactivated derivatives, IS30 family
BRL61_RS04960	COG0747	negative chemotaxis
BRL61_RS04965	COG0444	Belongs to the ABC transporter superfamily
BRL61_RS04975	COG0601	transmembrane transport
BRL61_RS04980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRL61_RS04985	COG2801	Transposase and inactivated derivatives
BRL61_RS05020	COG1164	Oligoendopeptidase f
BRL61_RS05030	COG2346	COG2346, Truncated hemoglobins
BRL61_RS05045	COG2357	RelA SpoT domain protein
BRL61_RS05055	COG0564	pseudouridine synthase activity
BRL61_RS05060	COG2239	Acts as a magnesium transporter
BRL61_RS05065	COG0569	domain protein
BRL61_RS05065	COG0475	glutathione-regulated potassium exporter activity
BRL61_RS05075	COG0628	permease
BRL61_RS05080	COG1115	amino acid carrier protein
BRL61_RS05130	COG0861	Integral membrane protein TerC family
BRL61_RS05140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BRL61_RS05145	COG0737	Belongs to the 5'-nucleotidase family
BRL61_RS05160	COG4903	ComK protein
BRL61_RS05175	COG4873	Protein conserved in bacteria
BRL61_RS05235	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BRL61_RS05245	COG2314	TM2 domain
BRL61_RS05250	COG0456	acetyltransferase
BRL61_RS05255	COG1575	Belongs to the MenA family. Type 1 subfamily
BRL61_RS05265	COG1169	isochorismate synthase
BRL61_RS05275	COG2267	carboxylic ester hydrolase activity
BRL61_RS05305	COG0436	Aminotransferase
BRL61_RS05310	COG3594	Acyltransferase
BRL61_RS05340	COG1316	TRANSCRIPTIONal
BRL61_RS05390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BRL61_RS05405	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BRL61_RS05450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BRL61_RS05455	COG4172	Belongs to the ABC transporter superfamily
BRL61_RS05460	COG4721	ABC-type cobalt transport system, permease component
BRL61_RS05480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BRL61_RS05505	COG1271	oxidase subunit
BRL61_RS05510	COG1294	oxidase, subunit
BRL61_RS05515	COG0569	domain protein
BRL61_RS05585	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRL61_RS05590	COG1177	transmembrane transport
BRL61_RS05595	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BRL61_RS05620	COG0483	inositol monophosphate 1-phosphatase activity
BRL61_RS05630	COG1217	gtp-binding protein TYPA
BRL61_RS05640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BRL61_RS05650	COG0772	Belongs to the SEDS family
BRL61_RS05685	COG2340	Cysteine-rich secretory protein family
BRL61_RS05690	COG3679	Belongs to the UPF0342 family
BRL61_RS05695	COG0584	glycerophosphoryl diester phosphodiesterase
BRL61_RS05710	COG0742	ribosomal rna small subunit methyltransferase
BRL61_RS05770	COG4509	Sortase family
BRL61_RS05785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRL61_RS05815	COG1796	DNA polymerase
BRL61_RS05815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BRL61_RS05840	COG2009	succinate dehydrogenase
BRL61_RS05845	COG1053	succinate dehydrogenase
BRL61_RS05850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BRL61_RS05975	COG1288	antiporter activity
BRL61_RS06005	COG1011	Hydrolase
BRL61_RS06030	COG4839	cell division protein FtsL
BRL61_RS06035	COG0768	penicillin binding
BRL61_RS06070	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BRL61_RS06080	COG0762	integral membrane protein
BRL61_RS06085	COG2302	S4 RNA-binding domain
BRL61_RS06090	COG3599	regulation of cell shape
BRL61_RS06100	COG2826	transposase and inactivated derivatives, IS30 family
BRL61_RS06105	COG2514	catechol 2,3-dioxygenase activity
BRL61_RS06115	COG0564	pseudouridine synthase activity
BRL61_RS06125	COG2233	PERMEase
BRL61_RS06170	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BRL61_RS06185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BRL61_RS06190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BRL61_RS06200	COG2314	TM2 domain
BRL61_RS06215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRL61_RS06215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BRL61_RS06225	COG0631	protein serine/threonine phosphatase activity
BRL61_RS06240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BRL61_RS06255	COG1302	Protein conserved in bacteria
BRL61_RS06305	COG1196	nuclear chromosome segregation
BRL61_RS06310	COG0552	protein localization to endoplasmic reticulum
BRL61_RS06320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BRL61_RS06375	COG2348	transferase activity, transferring amino-acyl groups
BRL61_RS06380	COG0758	DNA mediated transformation
BRL61_RS06480	COG0195	Participates in both transcription termination and antitermination
BRL61_RS06485	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BRL61_RS06510	COG0196	riboflavin kinase activity
BRL61_RS06540	COG2188	Transcriptional regulator
BRL61_RS06545	COG0612	Peptidase, M16
BRL61_RS06550	COG0612	Peptidase, M16
BRL61_RS06555	COG0300	oxidoreductase activity
BRL61_RS06575	COG1058	Belongs to the CinA family
BRL61_RS06575	COG1546	Belongs to the CinA family
BRL61_RS06595	COG1692	metallophosphoesterase
BRL61_RS06600	COG0674	pyruvate-flavodoxin oxidoreductase activity
BRL61_RS06600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BRL61_RS06605	COG1013	pyruvate-flavodoxin oxidoreductase activity
BRL61_RS06640	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BRL61_RS06645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BRL61_RS06670	COG1923	regulation of RNA biosynthetic process
BRL61_RS06680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BRL61_RS06685	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BRL61_RS06690	COG0789	Transcriptional regulator
BRL61_RS06725	COG2826	transposase and inactivated derivatives, IS30 family
BRL61_RS06840	COG1131	(ABC) transporter
BRL61_RS06855	COG2197	response regulator
BRL61_RS06870	COG1525	nuclease
BRL61_RS06885	COG0527	aspartate kinase activity
BRL61_RS06890	COG0460	homoserine dehydrogenase
BRL61_RS06895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BRL61_RS06920	COG0833	amino acid
BRL61_RS06985	COG4846	Membrane protein involved in cytochrome C biogenesis
BRL61_RS07005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BRL61_RS07015	COG0824	Thioesterase
BRL61_RS07050	COG1115	amino acid carrier protein
BRL61_RS07065	COG0628	permease
BRL61_RS07095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BRL61_RS07105	COG1363	Peptidase, m42
BRL61_RS07110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BRL61_RS07115	COG0512	Glutamine amidotransferase of anthranilate synthase
BRL61_RS07205	COG0704	Plays a role in the regulation of phosphate uptake
BRL61_RS07215	COG0581	inorganic phosphate transmembrane transporter activity
BRL61_RS07220	COG0573	inorganic phosphate transmembrane transporter activity
BRL61_RS07235	COG0488	(ABC) transporter
BRL61_RS07240	COG0527	aspartate kinase activity
BRL61_RS07245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BRL61_RS07320	COG4548	von Willebrand factor, type A
BRL61_RS07325	COG0714	Associated with various cellular activities
BRL61_RS07375	COG0671	phosphoesterase, PA-phosphatase related
BRL61_RS07395	COG2826	transposase and inactivated derivatives, IS30 family
BRL61_RS07455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BRL61_RS07475	COG0531	amino acid
BRL61_RS07490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRL61_RS07495	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BRL61_RS07515	COG0116	Belongs to the methyltransferase superfamily
BRL61_RS07545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRL61_RS07545	COG4499	WXG100 protein secretion system (Wss), protein YukC
BRL61_RS07555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BRL61_RS07560	COG3935	DnaD domain protein
BRL61_RS07585	COG0438	transferase activity, transferring glycosyl groups
BRL61_RS07590	COG1694	Mazg nucleotide pyrophosphohydrolase
BRL61_RS07595	COG2738	Putative neutral zinc metallopeptidase
BRL61_RS07600	COG4347	Protein of unknown function (DUF1405)
BRL61_RS07635	COG0142	geranyltranstransferase activity
BRL61_RS07700	COG0492	ferredoxin-NADP+ reductase activity
BRL61_RS07715	COG0514	ATP-dependent DNA helicase (RecQ)
BRL61_RS07725	COG1141	Ferredoxin
BRL61_RS07775	COG0745	RESPONSE REGULATOR receiver
BRL61_RS07780	COG1187	pseudouridine synthase activity
BRL61_RS07805	COG0735	belongs to the Fur family
BRL61_RS07810	COG0494	nUDIX hydrolase
BRL61_RS07815	COG0667	Aldo Keto reductase
BRL61_RS07825	COG4221	oxidoreductase activity
BRL61_RS07840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRL61_RS07850	COG0366	Alpha amylase catalytic
BRL61_RS07855	COG1609	Transcriptional regulator
BRL61_RS07885	COG2195	Cleaves the N-terminal amino acid of tripeptides
BRL61_RS07895	COG4129	membrane
BRL61_RS07905	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRL61_RS07910	COG0022	dehydrogenase e1 component
BRL61_RS07915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRL61_RS07920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRL61_RS07925	COG0497	DNA recombination
BRL61_RS07955	COG1302	Protein conserved in bacteria
BRL61_RS07960	COG0439	Biotin carboxylase
BRL61_RS07965	COG0511	ligase activity, forming carbon-carbon bonds
BRL61_RS07975	COG0006	proline dipeptidase activity
BRL61_RS07990	COG0095	Lipoate-protein ligase
BRL61_RS07995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRL61_RS08040	COG4537	Required for transformation and DNA binding
BRL61_RS08045	COG1459	type II secretion system
BRL61_RS08050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BRL61_RS08055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRL61_RS08060	COG0011	TIGRFAM Protein of
BRL61_RS08065	COG1940	carbohydrate kinase activity
BRL61_RS08070	COG4483	Protein conserved in bacteria
BRL61_RS08080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BRL61_RS08090	COG0768	penicillin binding
BRL61_RS08105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BRL61_RS08110	COG1121	(ABC) transporter
BRL61_RS08120	COG0513	Belongs to the DEAD box helicase family
BRL61_RS08130	COG2384	SAM-dependent methyltransferase
BRL61_RS08150	COG0517	IMP dehydrogenase activity
BRL61_RS08170	COG0295	cytidine deaminase activity
BRL61_RS08185	COG1702	phosphate starvation-inducible protein PhoH
BRL61_RS08200	COG1030	water channel activity
BRL61_RS08210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BRL61_RS08215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BRL61_RS08245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BRL61_RS08265	COG1466	dna polymerase III delta subunit
BRL61_RS08270	COG2333	competence protein COMEC
BRL61_RS08270	COG0658	competence protein
BRL61_RS08275	COG2131	deaminase
BRL61_RS08285	COG2226	methyltransferase
BRL61_RS08290	COG0799	negative regulation of ribosome biogenesis
BRL61_RS08295	COG1713	HD superfamily hydrolase involved in NAD metabolism
BRL61_RS08305	COG1534	Rna-binding protein
BRL61_RS08315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BRL61_RS08320	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BRL61_RS08345	COG3177	Filamentation induced by cAMP protein fic
BRL61_RS08350	COG1914	H( )-stimulated, divalent metal cation uptake system
BRL61_RS08360	COG0439	Biotin carboxylase
BRL61_RS08365	COG0511	ligase activity, forming carbon-carbon bonds
BRL61_RS08370	COG1984	allophanate hydrolase subunit 2
BRL61_RS08375	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BRL61_RS08390	COG0826	peptidase U32
BRL61_RS08395	COG0826	peptidase U32
BRL61_RS08425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BRL61_RS08450	COG1104	cysteine desulfurase activity
BRL61_RS08455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRL61_RS08465	COG3237	CsbD-like
BRL61_RS08470	COG1959	2 iron, 2 sulfur cluster binding
BRL61_RS08475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BRL61_RS08480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BRL61_RS08525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BRL61_RS08525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BRL61_RS08530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRL61_RS08530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRL61_RS08535	COG1862	Preprotein translocase
BRL61_RS08575	COG2868	ribosomal protein
BRL61_RS08620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BRL61_RS08630	COG0285	dihydrofolate synthase activity
BRL61_RS08640	COG2818	Glycosylase
BRL61_RS08675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRL61_RS08710	COG4112	unkown
BRL61_RS08735	COG0833	amino acid
BRL61_RS08750	COG1484	DNA-dependent DNA replication
BRL61_RS08780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRL61_RS08780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRL61_RS08790	COG5002	protein histidine kinase activity
BRL61_RS08795	COG0745	RESPONSE REGULATOR receiver
BRL61_RS08810	COG0372	Belongs to the citrate synthase family
BRL61_RS08815	COG1113	amino acid transport
BRL61_RS08840	COG0281	malic enzyme
BRL61_RS08850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BRL61_RS08860	COG4109	DRTGG domain
BRL61_RS08900	COG0827	DNA restriction-modification system
BRL61_RS08910	COG0730	response to heat
BRL61_RS08920	COG1104	cysteine desulfurase activity
BRL61_RS08935	COG1956	GAF domain-containing protein
BRL61_RS08950	COG0584	glycerophosphoryl diester phosphodiesterase
BRL61_RS08955	COG1764	response to oxidative stress
BRL61_RS08960	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BRL61_RS08965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRL61_RS08980	COG1263	PTS System
BRL61_RS08980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL61_RS08985	COG0204	Acyl-transferase
BRL61_RS08990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRL61_RS09020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRL61_RS09025	COG0454	-acetyltransferase
BRL61_RS09045	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BRL61_RS09045	COG1605	Chorismate mutase
BRL61_RS09070	COG1674	ftsk spoiiie
BRL61_RS09075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRL61_RS09085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL61_RS09090	COG1363	Peptidase, m42
BRL61_RS09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRL61_RS09110	COG0510	thiamine kinase activity
BRL61_RS09130	COG1187	pseudouridine synthase activity
BRL61_RS09135	COG2244	polysaccharide biosynthetic process
BRL61_RS09140	COG2081	HI0933 family
BRL61_RS09160	COG2814	Major facilitator Superfamily
BRL61_RS09165	COG1242	4 iron, 4 sulfur cluster binding
BRL61_RS09170	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BRL61_RS09180	COG2267	carboxylic ester hydrolase activity
BRL61_RS09215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRL61_RS09215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRL61_RS09235	COG3266	domain, Protein
BRL61_RS09235	COG4193	domain, Protein
BRL61_RS09235	COG5632	N-Acetylmuramoyl-L-alanine amidase
BRL61_RS09270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BRL61_RS09290	COG0656	L-ascorbic acid biosynthetic process
BRL61_RS09310	COG1506	peptidase
BRL61_RS09315	COG2816	NAD+ diphosphatase activity
BRL61_RS09405	COG5492	domain, Protein
BRL61_RS09595	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BRL61_RS09625	COG1131	(ABC) transporter
BRL61_RS09630	COG0537	adenosine 5'-monophosphoramidase activity
BRL61_RS09660	COG0420	3'-5' exonuclease activity
BRL61_RS09690	COG2197	response regulator
BRL61_RS09695	COG4585	Histidine kinase
BRL61_RS09695	COG2203	Gaf domain
BRL61_RS09700	COG0564	pseudouridine synthase activity
BRL61_RS09730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BRL61_RS09735	COG1126	abc transporter atp-binding protein
BRL61_RS09740	COG0765	amino acid transport
BRL61_RS09905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRL61_RS09910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRL61_RS09920	COG4129	membrane
BRL61_RS09935	COG1194	a g-specific adenine glycosylase
BRL61_RS09940	COG1988	membrane-bound metal-dependent
BRL61_RS09955	COG1388	LysM domain
BRL61_RS09955	COG1134	teichoic acid transport
BRL61_RS09985	COG2826	transposase and inactivated derivatives, IS30 family
BRL61_RS10015	COG5632	N-Acetylmuramoyl-L-alanine amidase
BRL61_RS10015	COG1388	LysM domain
BRL61_RS10060	COG0739	heme binding
BRL61_RS10120	COG4695	Portal protein
BRL61_RS10235	COG1484	DNA-dependent DNA replication
BRL61_RS10290	COG3645	SOS response
BRL61_RS10290	COG3646	Phage regulatory protein
BRL61_RS10345	COG0535	radical SAM domain protein
BRL61_RS10350	COG1607	acyl-coa hydrolase
BRL61_RS10355	COG2309	aminopeptidase activity
BRL61_RS10375	COG1295	ribonuclease BN
BRL61_RS10510	COG4851	CamS sex pheromone cAM373 precursor
BRL61_RS10530	COG4496	protein, YerC YecD
BRL61_RS10565	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BRL61_RS10575	COG0077	Prephenate dehydratase
BRL61_RS10595	COG1335	isochorismatase
BRL61_RS10610	COG1012	belongs to the aldehyde dehydrogenase family
BRL61_RS10660	COG1131	(ABC) transporter
BRL61_RS10675	COG1725	Transcriptional regulator
BRL61_RS10725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BRL61_RS10810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRL61_RS10815	COG1621	beta-fructofuranosidase activity
BRL61_RS10820	COG1609	Transcriptional regulator
BRL61_RS10825	COG0004	ammonium transporteR
BRL61_RS10830	COG0425	Belongs to the sulfur carrier protein TusA family
BRL61_RS10835	COG2391	methyltransferase activity
BRL61_RS10845	COG0488	(ABC) transporter
BRL61_RS10855	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BRL61_RS10865	COG0456	acetyltransferase
BRL61_RS10870	COG1214	PFAM Peptidase M22, glycoprotease
BRL61_RS10875	COG0802	atpase or kinase
BRL61_RS10890	COG0028	Belongs to the TPP enzyme family
BRL61_RS10935	COG2801	Transposase and inactivated derivatives
BRL61_RS10980	COG2183	response to ionizing radiation
BRL61_RS10985	COG1191	sigma factor activity
BRL61_RS10995	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL61_RS11000	COG2208	phosphoserine phosphatase activity
BRL61_RS11035	COG3428	Bacterial PH domain
BRL61_RS11065	COG2205	protein histidine kinase activity
BRL61_RS11070	COG0745	RESPONSE REGULATOR receiver
BRL61_RS11080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BRL61_RS11090	COG0772	Belongs to the SEDS family
BRL61_RS11110	COG1937	Protein conserved in bacteria
BRL61_RS11120	COG1418	mRNA catabolic process
BRL61_RS11170	COG0629	single-stranded DNA binding
BRL61_RS11255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BRL61_RS11280	COG0009	L-threonylcarbamoyladenylate synthase
BRL61_RS11285	COG2890	protein-(glutamine-N5) methyltransferase activity
BRL61_RS11310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BRL61_RS11350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRL61_RS11400	COG0813	purine-nucleoside phosphorylase activity
BRL61_RS11405	COG0783	Belongs to the Dps family
BRL61_RS11425	COG1482	cell wall glycoprotein biosynthetic process
BRL61_RS11430	COG0702	epimerase
BRL61_RS11435	COG0640	Transcriptional regulator
BRL61_RS11470	COG0561	phosphatase activity
BRL61_RS11475	COG1119	ATPase activity
BRL61_RS11495	COG3711	transcriptional antiterminator
BRL61_RS11525	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BRL61_RS11585	COG0489	protein tyrosine kinase activity
BRL61_RS11590	COG2814	Major facilitator Superfamily
BRL61_RS11605	COG1272	protein, Hemolysin III
BRL61_RS11615	COG1988	membrane-bound metal-dependent
BRL61_RS11625	COG3314	Sporulation integral membrane protein YlbJ
BRL61_RS11630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL61_RS11635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL61_RS11640	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BRL61_RS11650	COG3457	Alanine racemase
BRL61_RS11655	COG4264	IucA IucC family
BRL61_RS11660	COG2814	Major facilitator Superfamily
BRL61_RS11685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BRL61_RS11695	COG2130	NADP-dependent
BRL61_RS11760	COG0656	L-ascorbic acid biosynthetic process
BRL61_RS11765	COG0789	Transcriptional regulator
BRL61_RS11775	COG5492	domain, Protein
BRL61_RS11795	COG3527	Alpha-acetolactate decarboxylase
BRL61_RS11800	COG0028	Belongs to the TPP enzyme family
BRL61_RS11890	COG0201	protein transport
BRL61_RS12005	COG2252	PERMEase
BRL61_RS12045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRL61_RS12115	COG1763	Mo-molybdopterin cofactor biosynthetic process
BRL61_RS12135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BRL61_RS12140	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BRL61_RS12145	COG4149	molybdate abc transporter
BRL61_RS12150	COG0725	ABC transporter, periplasmic molybdate-binding protein
BRL61_RS12165	COG1268	BioY protein
BRL61_RS12180	COG1960	acyl-CoA dehydrogenase activity
BRL61_RS12185	COG4413	Urea transporter
BRL61_RS12260	COG1757	Na H antiporter
BRL61_RS12275	COG3942	CHAP domain
BRL61_RS12355	COG1113	amino acid transport
BRL61_RS12375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BRL61_RS12380	COG0385	Bile acid
BRL61_RS12390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL61_RS12390	COG1263	PTS System
BRL61_RS12395	COG1737	Transcriptional regulator
BRL61_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
BRL61_RS12420	COG1473	amidohydrolase
BRL61_RS12435	COG0583	DNA-binding transcription factor activity
BRL61_RS12460	COG2258	MOSC domain
BRL61_RS12480	COG1668	transmembrane transport
BRL61_RS12485	COG4152	abc transporter atp-binding protein
BRL61_RS12505	COG0786	glutamate:sodium symporter activity
BRL61_RS12515	COG0598	Magnesium transport protein CorA
BRL61_RS12530	COG0657	acetylesterase activity
BRL61_RS12540	COG2814	Major facilitator Superfamily
BRL61_RS12545	COG1566	PFAM secretion protein HlyD family protein
BRL61_RS12560	COG2814	Major facilitator Superfamily
BRL61_RS12625	COG1131	(ABC) transporter
BRL61_RS12640	COG1620	l-lactate permease
BRL61_RS12660	COG0604	alcohol dehydrogenase
BRL61_RS12690	COG1511	domain protein
BRL61_RS12705	COG1263	PTS System
BRL61_RS12705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL61_RS12720	COG3871	stress protein (general stress protein 26)
BRL61_RS12765	COG0789	Transcriptional regulator
BRL61_RS12785	COG2181	nitrate reductase activity
BRL61_RS12795	COG1140	nitrate reductase beta subunit
BRL61_RS12800	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BRL61_RS12810	COG2146	nitrite reductase [NAD(P)H] activity
BRL61_RS12815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BRL61_RS12825	COG0454	-acetyltransferase
BRL61_RS12835	COG2116	formate transmembrane transporter activity
BRL61_RS12850	COG0803	Belongs to the bacterial solute-binding protein 9 family
BRL61_RS12850	COG3443	Belongs to the bacterial solute-binding protein 9 family
BRL61_RS12885	COG1126	abc transporter atp-binding protein
BRL61_RS12890	COG0765	amino acid transport
BRL61_RS12895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRL61_RS12900	COG2814	Major facilitator Superfamily
BRL61_RS12920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BRL61_RS12970	COG0156	8-amino-7-oxononanoate synthase activity
BRL61_RS12980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BRL61_RS12985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BRL61_RS13000	COG1132	(ABC) transporter
BRL61_RS13005	COG1132	(ABC) transporter
BRL61_RS13005	COG2375	cellular response to nickel ion
BRL61_RS13025	COG1929	Belongs to the glycerate kinase type-1 family
BRL61_RS13035	COG2814	Major facilitator Superfamily
BRL61_RS13055	COG1113	amino acid transport
BRL61_RS13070	COG0531	amino acid
BRL61_RS13090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRL61_RS13100	COG1174	glycine betaine transport
BRL61_RS13110	COG1174	glycine betaine transport
BRL61_RS13120	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BRL61_RS13125	COG0531	amino acid
BRL61_RS13130	COG2272	Belongs to the type-B carboxylesterase lipase family
BRL61_RS13135	COG2814	Major facilitator Superfamily
BRL61_RS13140	COG0390	transport system, permease component
BRL61_RS13145	COG4619	ABC transporter
BRL61_RS13150	COG1363	Peptidase, m42
BRL61_RS13170	COG4808	Protein conserved in bacteria
BRL61_RS13175	COG0069	glutamate synthase activity
BRL61_RS13190	COG1124	(ABC) transporter
BRL61_RS13200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRL61_RS13205	COG0601	transmembrane transport
BRL61_RS13210	COG0747	negative chemotaxis
BRL61_RS13230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BRL61_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
BRL61_RS13240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BRL61_RS13245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRL61_RS13325	COG0494	nUDIX hydrolase
BRL61_RS13375	COG1070	Carbohydrate kinase
BRL61_RS13380	COG1802	Transcriptional regulator
BRL61_RS13385	COG0789	Transcriptional regulator
BRL61_RS13390	COG2357	RelA SpoT domain protein
BRL61_RS13395	COG4876	unkown
BRL61_RS13405	COG2271	Major facilitator Superfamily
BRL61_RS13410	COG0586	Pfam SNARE associated Golgi protein
BRL61_RS13415	COG1279	arginine transmembrane transporter activity
BRL61_RS13425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRL61_RS13440	COG1131	(ABC) transporter
BRL61_RS13460	COG0400	carboxylic ester hydrolase activity
BRL61_RS13465	COG0346	lactoylglutathione lyase activity
BRL61_RS13470	COG1846	Transcriptional regulator
BRL61_RS13480	COG2514	catechol 2,3-dioxygenase activity
BRL61_RS13500	COG0561	phosphatase activity
BRL61_RS13505	COG3764	Sortase (surface protein transpeptidase)
BRL61_RS13530	COG1760	l-serine dehydratase
BRL61_RS13535	COG1760	l-serine dehydratase
BRL61_RS13550	COG0697	spore germination
BRL61_RS13555	COG0657	acetylesterase activity
BRL61_RS13575	COG0028	Belongs to the TPP enzyme family
BRL61_RS13590	COG0583	DNA-binding transcription factor activity
BRL61_RS13600	COG3942	CHAP domain
BRL61_RS13610	COG3425	synthase
BRL61_RS13615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BRL61_RS13640	COG2409	Drug exporters of the RND superfamily
BRL61_RS13690	COG0436	Aminotransferase
BRL61_RS13825	COG3001	Fructosamine kinase
BRL61_RS13830	COG0167	dihydroorotate dehydrogenase activity
BRL61_RS13885	COG3527	Alpha-acetolactate decarboxylase
BRL61_RS13900	COG0531	amino acid
BRL61_RS13930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRL61_RS13950	COG1012	belongs to the aldehyde dehydrogenase family
BRL61_RS13960	COG1510	regulation of RNA biosynthetic process
BRL61_RS13965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BRL61_RS13990	COG2851	Citrate transporter
BRL61_RS14005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BRL61_RS14015	COG0386	Belongs to the glutathione peroxidase family
BRL61_RS14040	COG1136	(ABC) transporter
BRL61_RS14045	COG2205	protein histidine kinase activity
BRL61_RS14050	COG0745	RESPONSE REGULATOR receiver
BRL61_RS14060	COG1785	Belongs to the alkaline phosphatase family
BRL61_RS14070	COG1846	Transcriptional regulator
BRL61_RS14115	COG1438	arginine binding
BRL61_RS14135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL61_RS14135	COG3711	transcriptional antiterminator
BRL61_RS14140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL61_RS14140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL61_RS14140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL61_RS14145	COG1482	cell wall glycoprotein biosynthetic process
BRL61_RS14155	COG1705	Flagellar rod assembly protein muramidase FlgJ
BRL61_RS14155	COG3942	CHAP domain
BRL61_RS14160	COG3433	isochorismatase activity
BRL61_RS14160	COG1535	isochorismatase
BRL61_RS14175	COG0438	transferase activity, transferring glycosyl groups
BRL61_RS14190	COG1073	alpha beta
BRL61_RS14210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BRL61_RS14235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BRL61_RS14325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BRL61_RS14405	COG0471	metal ion transport
BRL61_RS14415	COG2962	Rard protein
BRL61_RS14425	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BRL61_RS14440	COG1136	(ABC) transporter
BRL61_RS14445	COG0577	efflux transmembrane transporter activity
BRL61_RS14470	COG1404	Belongs to the peptidase S8 family
BRL61_RS14475	COG1278	Cold shock
BRL61_RS14505	COG1475	DNA binding