locus-tag	class	description
SAST43_RS00015	COG2501	S4 domain
SAST43_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAST43_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SAST43_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SAST43_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
SAST43_RS00110	COG4863	YycH protein
SAST43_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAST43_RS00125	COG0737	Belongs to the 5'-nucleotidase family
SAST43_RS00140	COG1401	restriction endodeoxyribonuclease activity
SAST43_RS00145	COG4268	DNA restriction-modification system
SAST43_RS00150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SAST43_RS00150	COG1199	ATP-dependent helicase activity
SAST43_RS00160	COG0456	acetyltransferase
SAST43_RS00185	COG1073	alpha beta
SAST43_RS00195	COG2226	methyltransferase
SAST43_RS00205	COG0823	Involved in the tonB-independent uptake of proteins
SAST43_RS00265	COG1473	amidohydrolase
SAST43_RS00280	COG1283	sodium-dependent phosphate transmembrane transporter activity
SAST43_RS00285	COG4716	Myosin-crossreactive antigen
SAST43_RS00290	COG0697	spore germination
SAST43_RS00305	COG1620	l-lactate permease
SAST43_RS00320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAST43_RS00325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAST43_RS00330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAST43_RS00340	COG2423	ornithine cyclodeaminase activity
SAST43_RS00345	COG4264	IucA IucC family
SAST43_RS00350	COG2814	Major facilitator Superfamily
SAST43_RS00355	COG4264	IucA IucC family
SAST43_RS00360	COG4264	IucA IucC family
SAST43_RS00370	COG0019	diaminopimelate decarboxylase activity
SAST43_RS00375	COG1475	DNA binding
SAST43_RS00400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAST43_RS00405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAST43_RS00410	COG0438	transferase activity, transferring glycosyl groups
SAST43_RS00445	COG0813	purine-nucleoside phosphorylase activity
SAST43_RS00450	COG2814	Major facilitator Superfamily
SAST43_RS00470	COG3639	organic phosphonate transmembrane transporter activity
SAST43_RS00490	COG0737	Belongs to the 5'-nucleotidase family
SAST43_RS00520	COG1012	belongs to the aldehyde dehydrogenase family
SAST43_RS00520	COG1454	alcohol dehydrogenase
SAST43_RS00545	COG1086	Polysaccharide biosynthesis protein
SAST43_RS00555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAST43_RS00585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAST43_RS00595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SAST43_RS00600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAST43_RS00610	COG2832	Protein of unknown function (DUF454)
SAST43_RS00645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAST43_RS00650	COG1960	acyl-CoA dehydrogenase activity
SAST43_RS00655	COG5609	conserved protein (DUF2294)
SAST43_RS00705	COG1114	Component of the transport system for branched-chain amino acids
SAST43_RS00710	COG1335	isochorismatase
SAST43_RS00715	COG3961	Belongs to the TPP enzyme family
SAST43_RS00745	COG1737	Transcriptional regulator
SAST43_RS00770	COG1136	(ABC) transporter
SAST43_RS00775	COG1136	(ABC) transporter
SAST43_RS00775	COG0577	efflux transmembrane transporter activity
SAST43_RS00795	COG1131	(ABC) transporter
SAST43_RS00815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAST43_RS00825	COG0405	Gamma-glutamyltransferase
SAST43_RS00845	COG3842	ATPase activity
SAST43_RS00855	COG1175	transmembrane transport
SAST43_RS00860	COG3833	ABC-type maltose transport systems, permease component
SAST43_RS00865	COG0673	inositol 2-dehydrogenase activity
SAST43_RS00870	COG0673	inositol 2-dehydrogenase activity
SAST43_RS00880	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAST43_RS00945	COG0183	Belongs to the thiolase family
SAST43_RS00955	COG1960	acyl-CoA dehydrogenase activity
SAST43_RS00975	COG0747	negative chemotaxis
SAST43_RS00980	COG3189	MarR family transcriptional regulator
SAST43_RS01010	COG2190	(PTS) system
SAST43_RS01010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAST43_RS01010	COG1263	PTS System
SAST43_RS01015	COG1957	nucleoside hydrolase
SAST43_RS01035	COG3414	Phosphotransferase system galactitol-specific IIB component
SAST43_RS01040	COG3775	system Galactitol-specific IIC component
SAST43_RS01045	COG1063	alcohol dehydrogenase
SAST43_RS01055	COG1063	alcohol dehydrogenase
SAST43_RS01065	COG1063	alcohol dehydrogenase
SAST43_RS01070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAST43_RS01080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAST43_RS01090	COG1063	alcohol dehydrogenase
SAST43_RS01095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAST43_RS01130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAST43_RS01135	COG1263	PTS System
SAST43_RS01135	COG2190	(PTS) system
SAST43_RS01135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAST43_RS01140	COG2723	6-phospho-beta-galactosidase activity
SAST43_RS01150	COG2226	methyltransferase
SAST43_RS01205	COG1131	(ABC) transporter
SAST43_RS01225	COG1388	LysM domain
SAST43_RS01225	COG3942	CHAP domain
SAST43_RS01360	COG1114	Component of the transport system for branched-chain amino acids
SAST43_RS01365	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAST43_RS01375	COG0577	efflux transmembrane transporter activity
SAST43_RS01400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAST43_RS01405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SAST43_RS01430	COG3314	Sporulation integral membrane protein YlbJ
SAST43_RS01455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAST43_RS01480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAST43_RS01485	COG3037	sugar-specific permease SgaT UlaA
SAST43_RS01495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAST43_RS01500	COG3711	transcriptional antiterminator
SAST43_RS01520	COG2271	Major facilitator Superfamily
SAST43_RS01530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAST43_RS01535	COG0431	NADPH-dependent FMN reductase
SAST43_RS01550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAST43_RS01555	COG2822	iron ion transport
SAST43_RS01565	COG0672	)-iron permease
SAST43_RS01570	COG0805	protein transport
SAST43_RS01575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAST43_RS01585	COG1476	TRANSCRIPTIONal
SAST43_RS01595	COG1131	(ABC) transporter
SAST43_RS01630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAST43_RS01630	COG0646	methionine synthase
SAST43_RS01635	COG0626	cystathionine gamma-synthase activity
SAST43_RS01640	COG0626	cystathionine gamma-synthase activity
SAST43_RS01645	COG1475	DNA binding
SAST43_RS01650	COG0668	transmembrane transport
SAST43_RS01655	COG4481	Protein conserved in bacteria
SAST43_RS01660	COG0012	GTP binding
SAST43_RS01760	COG1823	symporter activity
SAST43_RS01790	COG2233	PERMEase
SAST43_RS01860	COG3759	membrane
SAST43_RS01985	COG0523	cobalamin synthesis protein
SAST43_RS01995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SAST43_RS02005	COG5609	conserved protein (DUF2294)
SAST43_RS02020	COG1647	Serine aminopeptidase, S33
SAST43_RS02030	COG0733	neurotransmitter:sodium symporter activity
SAST43_RS02035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAST43_RS02040	COG0626	cystathionine gamma-synthase activity
SAST43_RS02050	COG2011	ABC-type metal ion transport system permease component
SAST43_RS02055	COG1464	Belongs to the NlpA lipoprotein family
SAST43_RS02090	COG0583	DNA-binding transcription factor activity
SAST43_RS02095	COG0067	glutamate synthase
SAST43_RS02095	COG0070	glutamate synthase
SAST43_RS02095	COG0069	glutamate synthase activity
SAST43_RS02100	COG0493	'glutamate synthase
SAST43_RS02110	COG1263	PTS System
SAST43_RS02110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAST43_RS02115	COG0366	Alpha amylase catalytic
SAST43_RS02120	COG2188	Transcriptional regulator
SAST43_RS02140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAST43_RS02175	COG1982	Orn Lys Arg decarboxylase major
SAST43_RS02185	COG3870	Protein conserved in bacteria
SAST43_RS02195	COG0470	DNA polymerase III
SAST43_RS02200	COG1774	PSP1 C-terminal conserved region
SAST43_RS02210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAST43_RS02220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SAST43_RS02235	COG0084	hydrolase, TatD family'
SAST43_RS02240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAST43_RS02250	COG4466	Protein conserved in bacteria
SAST43_RS02260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAST43_RS02265	COG0251	oxidation-reduction process
SAST43_RS02310	COG2244	polysaccharide biosynthetic process
SAST43_RS02315	COG3956	TIGRFAM MazG family protein
SAST43_RS02320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAST43_RS02330	COG1098	S1 RNA binding domain
SAST43_RS02345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAST43_RS02370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAST43_RS02465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAST43_RS02480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAST43_RS02490	COG3880	PFAM UvrB UvrC protein
SAST43_RS02510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SAST43_RS02515	COG4956	integral membrane protein (PIN domain superfamily)
SAST43_RS02535	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAST43_RS02585	COG2813	Specifically methylates the guanine in position
SAST43_RS02625	COG1473	amidohydrolase
SAST43_RS02655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAST43_RS02660	COG1428	Deoxynucleoside kinase
SAST43_RS02665	COG1428	Deoxynucleoside kinase
SAST43_RS02675	COG0561	phosphatase activity
SAST43_RS02715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAST43_RS02730	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SAST43_RS02820	COG0095	Lipoate-protein ligase
SAST43_RS02825	COG0083	homoserine kinase activity
SAST43_RS02845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAST43_RS02960	COG0667	Aldo Keto reductase
SAST43_RS02965	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAST43_RS02975	COG1078	dGTPase activity
SAST43_RS03010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAST43_RS03015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAST43_RS03065	COG4974	Belongs to the 'phage' integrase family
SAST43_RS03110	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAST43_RS03115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAST43_RS03120	COG1121	(ABC) transporter
SAST43_RS03125	COG1321	iron dependent repressor
SAST43_RS03135	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SAST43_RS03145	COG1682	transport, permease protein
SAST43_RS03150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAST43_RS03155	COG1216	Glycosyl transferase, family 2
SAST43_RS03160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SAST43_RS03165	COG1686	Belongs to the peptidase S11 family
SAST43_RS03170	COG1132	(ABC) transporter
SAST43_RS03175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAST43_RS03185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAST43_RS03190	COG1120	ATPase activity
SAST43_RS03195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAST43_RS03200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAST43_RS03205	COG2376	Dihydroxyacetone kinase
SAST43_RS03215	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAST43_RS03225	COG3949	Membrane
SAST43_RS03250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAST43_RS03265	COG1136	(ABC) transporter
SAST43_RS03270	COG0577	efflux transmembrane transporter activity
SAST43_RS03275	COG1392	Phosphate transport regulator
SAST43_RS03280	COG0306	phosphate transporter
SAST43_RS03285	COG3942	CHAP domain
SAST43_RS03285	COG1388	LysM domain
SAST43_RS03300	COG1917	Cupin 2, conserved barrel domain protein
SAST43_RS03300	COG4977	sequence-specific DNA binding
SAST43_RS03330	COG0583	DNA-binding transcription factor activity
SAST43_RS03335	COG2814	Major facilitator Superfamily
SAST43_RS03340	COG2839	Protein conserved in bacteria
SAST43_RS03370	COG1611	Belongs to the LOG family
SAST43_RS03390	COG4988	ABC transporter
SAST43_RS03395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAST43_RS03405	COG0523	cobalamin synthesis protein
SAST43_RS03410	COG4989	oxidoreductase activity
SAST43_RS03420	COG0471	metal ion transport
SAST43_RS03425	COG0415	Belongs to the DNA photolyase family
SAST43_RS03455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAST43_RS03460	COG1349	DNA-binding transcription factor activity
SAST43_RS03465	COG1105	Belongs to the carbohydrate kinase PfkB family
SAST43_RS03470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAST43_RS03470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAST43_RS03470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAST43_RS03480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SAST43_RS03485	COG1253	flavin adenine dinucleotide binding
SAST43_RS03490	COG0656	L-ascorbic acid biosynthetic process
SAST43_RS03495	COG0463	Glycosyl transferase, family 2
SAST43_RS03530	COG0720	synthase
SAST43_RS03540	COG0512	Glutamine amidotransferase of anthranilate synthase
SAST43_RS03540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SAST43_RS03545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAST43_RS03580	COG0488	(ABC) transporter
SAST43_RS03585	COG0514	ATP-dependent DNA helicase (RecQ)
SAST43_RS03590	COG0517	IMP dehydrogenase activity
SAST43_RS03590	COG1125	glycine betaine transport
SAST43_RS03595	COG1174	glycine betaine transport
SAST43_RS03620	COG3104	oligopeptide transport
SAST43_RS03640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAST43_RS03645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAST43_RS03655	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAST43_RS03660	COG4605	iron ion homeostasis
SAST43_RS03665	COG4604	ABC transporter, ATP-binding protein
SAST43_RS03670	COG4607	ABC-type enterochelin transport system periplasmic component
SAST43_RS03725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAST43_RS03730	COG1739	Uncharacterized protein family UPF0029
SAST43_RS03740	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAST43_RS03745	COG1040	competence protein
SAST43_RS03775	COG1388	LysM domain
SAST43_RS03775	COG3942	CHAP domain
SAST43_RS03835	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SAST43_RS03900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SAST43_RS03905	COG1647	Serine aminopeptidase, S33
SAST43_RS03910	COG0557	exoribonuclease II activity
SAST43_RS03970	COG1278	Cold shock
SAST43_RS04010	COG0406	alpha-ribazole phosphatase activity
SAST43_RS04015	COG1279	arginine transmembrane transporter activity
SAST43_RS04040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAST43_RS04045	COG1393	Belongs to the ArsC family
SAST43_RS04060	COG3878	Protein conserved in bacteria
SAST43_RS04070	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAST43_RS04085	COG2011	ABC-type metal ion transport system permease component
SAST43_RS04090	COG1464	Belongs to the NlpA lipoprotein family
SAST43_RS04105	COG0396	ATPase activity
SAST43_RS04110	COG0719	Fe-S assembly protein
SAST43_RS04120	COG0822	iron-sulfur transferase activity
SAST43_RS04140	COG1253	flavin adenine dinucleotide binding
SAST43_RS04155	COG1801	Protein of unknown function DUF72
SAST43_RS04160	COG0730	response to heat
SAST43_RS04175	COG4470	Protein conserved in bacteria
SAST43_RS04185	COG2445	Protein of unknown function DUF86
SAST43_RS04215	COG1696	Membrane protein involved in D-alanine export
SAST43_RS04225	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAST43_RS04230	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SAST43_RS04235	COG4837	Protein of unknown function (DUF1462)
SAST43_RS04240	COG1252	NADH dehydrogenase
SAST43_RS04250	COG0316	Belongs to the HesB IscA family
SAST43_RS04260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SAST43_RS04265	COG2056	Na+-H+ antiporter family
SAST43_RS04270	COG2050	protein possibly involved in aromatic compounds catabolism
SAST43_RS04325	COG1098	S1 RNA binding domain
SAST43_RS04330	COG1902	pentaerythritol trinitrate reductase activity
SAST43_RS04350	COG0584	glycerophosphoryl diester phosphodiesterase
SAST43_RS04370	COG0398	Pfam SNARE associated Golgi protein
SAST43_RS04415	COG0561	phosphatase activity
SAST43_RS04440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SAST43_RS04455	COG1881	PFAM PEBP family protein
SAST43_RS04485	COG0601	transmembrane transport
SAST43_RS04490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAST43_RS04495	COG0444	Belongs to the ABC transporter superfamily
SAST43_RS04500	COG4608	Belongs to the ABC transporter superfamily
SAST43_RS04505	COG4166	transmembrane transport
SAST43_RS04510	COG0747	negative chemotaxis
SAST43_RS04515	COG0444	Belongs to the ABC transporter superfamily
SAST43_RS04520	COG4608	Belongs to the ABC transporter superfamily
SAST43_RS04525	COG0601	transmembrane transport
SAST43_RS04530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAST43_RS04555	COG1164	Oligoendopeptidase f
SAST43_RS04565	COG2346	COG2346, Truncated hemoglobins
SAST43_RS04580	COG2357	RelA SpoT domain protein
SAST43_RS04590	COG0564	pseudouridine synthase activity
SAST43_RS04595	COG2239	Acts as a magnesium transporter
SAST43_RS04600	COG0569	domain protein
SAST43_RS04600	COG0475	glutathione-regulated potassium exporter activity
SAST43_RS04610	COG0628	permease
SAST43_RS04615	COG1115	amino acid carrier protein
SAST43_RS04670	COG0861	Integral membrane protein TerC family
SAST43_RS04680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAST43_RS04685	COG0737	Belongs to the 5'-nucleotidase family
SAST43_RS04715	COG4873	Protein conserved in bacteria
SAST43_RS04760	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAST43_RS04770	COG2314	TM2 domain
SAST43_RS04775	COG0456	acetyltransferase
SAST43_RS04780	COG1575	Belongs to the MenA family. Type 1 subfamily
SAST43_RS04785	COG1169	isochorismate synthase
SAST43_RS04795	COG2267	carboxylic ester hydrolase activity
SAST43_RS04820	COG0436	Aminotransferase
SAST43_RS04825	COG3594	Acyltransferase
SAST43_RS04855	COG1316	TRANSCRIPTIONal
SAST43_RS04900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAST43_RS04915	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAST43_RS04945	COG0138	bifunctional purine biosynthesis protein purh
SAST43_RS04955	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SAST43_RS04960	COG4172	Belongs to the ABC transporter superfamily
SAST43_RS04965	COG4721	ABC-type cobalt transport system, permease component
SAST43_RS04985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAST43_RS05005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAST43_RS05010	COG1271	oxidase subunit
SAST43_RS05015	COG1294	oxidase, subunit
SAST43_RS05020	COG0569	domain protein
SAST43_RS05090	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAST43_RS05095	COG1177	transmembrane transport
SAST43_RS05100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SAST43_RS05125	COG0483	inositol monophosphate 1-phosphatase activity
SAST43_RS05135	COG1217	gtp-binding protein TYPA
SAST43_RS05145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SAST43_RS05155	COG0772	Belongs to the SEDS family
SAST43_RS05190	COG3679	Belongs to the UPF0342 family
SAST43_RS05210	COG0742	ribosomal rna small subunit methyltransferase
SAST43_RS05270	COG4509	Sortase family
SAST43_RS05285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAST43_RS05315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SAST43_RS05315	COG1796	DNA polymerase
SAST43_RS05340	COG2009	succinate dehydrogenase
SAST43_RS05345	COG1053	succinate dehydrogenase
SAST43_RS05350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SAST43_RS05465	COG1288	antiporter activity
SAST43_RS05500	COG1011	Hydrolase
SAST43_RS05525	COG4839	cell division protein FtsL
SAST43_RS05530	COG0768	penicillin binding
SAST43_RS05545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SAST43_RS05550	COG0849	cell division
SAST43_RS05565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAST43_RS05575	COG0762	integral membrane protein
SAST43_RS05580	COG2302	S4 RNA-binding domain
SAST43_RS05585	COG3599	regulation of cell shape
SAST43_RS05595	COG2514	catechol 2,3-dioxygenase activity
SAST43_RS05610	COG0564	pseudouridine synthase activity
SAST43_RS05620	COG2233	PERMEase
SAST43_RS05665	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAST43_RS05680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAST43_RS05685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAST43_RS05695	COG2314	TM2 domain
SAST43_RS05710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAST43_RS05710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAST43_RS05720	COG0631	protein serine/threonine phosphatase activity
SAST43_RS05735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAST43_RS05750	COG1302	Protein conserved in bacteria
SAST43_RS05760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SAST43_RS05800	COG1196	nuclear chromosome segregation
SAST43_RS05805	COG0552	protein localization to endoplasmic reticulum
SAST43_RS05815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAST43_RS05865	COG0758	DNA mediated transformation
SAST43_RS05960	COG0195	Participates in both transcription termination and antitermination
SAST43_RS05965	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAST43_RS05990	COG0196	riboflavin kinase activity
SAST43_RS06015	COG2188	Transcriptional regulator
SAST43_RS06020	COG0612	Peptidase, M16
SAST43_RS06025	COG0612	Peptidase, M16
SAST43_RS06030	COG0300	oxidoreductase activity
SAST43_RS06050	COG1058	Belongs to the CinA family
SAST43_RS06050	COG1546	Belongs to the CinA family
SAST43_RS06070	COG1692	metallophosphoesterase
SAST43_RS06075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SAST43_RS06075	COG0674	pyruvate-flavodoxin oxidoreductase activity
SAST43_RS06080	COG1013	pyruvate-flavodoxin oxidoreductase activity
SAST43_RS06115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SAST43_RS06120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAST43_RS06145	COG1923	regulation of RNA biosynthetic process
SAST43_RS06155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAST43_RS06160	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SAST43_RS06165	COG0789	Transcriptional regulator
SAST43_RS06245	COG1131	(ABC) transporter
SAST43_RS06260	COG2197	response regulator
SAST43_RS06270	COG1525	nuclease
SAST43_RS06285	COG0527	aspartate kinase activity
SAST43_RS06290	COG0460	homoserine dehydrogenase
SAST43_RS06295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SAST43_RS06320	COG0833	amino acid
SAST43_RS06350	COG2340	Cysteine-rich secretory protein family
SAST43_RS06385	COG4846	Membrane protein involved in cytochrome C biogenesis
SAST43_RS06405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAST43_RS06420	COG0824	Thioesterase
SAST43_RS06440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SAST43_RS06450	COG1115	amino acid carrier protein
SAST43_RS06465	COG0628	permease
SAST43_RS06490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAST43_RS06500	COG1363	Peptidase, m42
SAST43_RS06505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAST43_RS06510	COG0512	Glutamine amidotransferase of anthranilate synthase
SAST43_RS06555	COG0561	phosphatase activity
SAST43_RS06600	COG0704	Plays a role in the regulation of phosphate uptake
SAST43_RS06610	COG0581	inorganic phosphate transmembrane transporter activity
SAST43_RS06615	COG0573	inorganic phosphate transmembrane transporter activity
SAST43_RS06640	COG0488	(ABC) transporter
SAST43_RS06645	COG0527	aspartate kinase activity
SAST43_RS06650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAST43_RS06725	COG4548	von Willebrand factor, type A
SAST43_RS06730	COG0714	Associated with various cellular activities
SAST43_RS06775	COG0671	phosphoesterase, PA-phosphatase related
SAST43_RS06855	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SAST43_RS06880	COG0531	amino acid
SAST43_RS06895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAST43_RS06900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SAST43_RS06920	COG0116	Belongs to the methyltransferase superfamily
SAST43_RS06955	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAST43_RS06955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAST43_RS06965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAST43_RS06970	COG3935	DnaD domain protein
SAST43_RS06995	COG0438	transferase activity, transferring glycosyl groups
SAST43_RS07000	COG1694	Mazg nucleotide pyrophosphohydrolase
SAST43_RS07005	COG2738	Putative neutral zinc metallopeptidase
SAST43_RS07010	COG4347	Protein of unknown function (DUF1405)
SAST43_RS07050	COG0142	geranyltranstransferase activity
SAST43_RS07115	COG0492	ferredoxin-NADP+ reductase activity
SAST43_RS07130	COG0514	ATP-dependent DNA helicase (RecQ)
SAST43_RS07140	COG1141	Ferredoxin
SAST43_RS07190	COG5002	protein histidine kinase activity
SAST43_RS07195	COG0745	RESPONSE REGULATOR receiver
SAST43_RS07200	COG1187	pseudouridine synthase activity
SAST43_RS07225	COG0735	belongs to the Fur family
SAST43_RS07230	COG0494	nUDIX hydrolase
SAST43_RS07235	COG0667	Aldo Keto reductase
SAST43_RS07245	COG4221	oxidoreductase activity
SAST43_RS07260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SAST43_RS07270	COG0366	Alpha amylase catalytic
SAST43_RS07275	COG1609	Transcriptional regulator
SAST43_RS07300	COG2195	Cleaves the N-terminal amino acid of tripeptides
SAST43_RS07310	COG4129	membrane
SAST43_RS07320	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAST43_RS07325	COG0022	dehydrogenase e1 component
SAST43_RS07330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAST43_RS07335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAST43_RS07340	COG0497	DNA recombination
SAST43_RS07370	COG1302	Protein conserved in bacteria
SAST43_RS07375	COG0439	Biotin carboxylase
SAST43_RS07380	COG0511	ligase activity, forming carbon-carbon bonds
SAST43_RS07390	COG0006	proline dipeptidase activity
SAST43_RS07405	COG0095	Lipoate-protein ligase
SAST43_RS07410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAST43_RS07455	COG4537	Required for transformation and DNA binding
SAST43_RS07465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAST43_RS07470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAST43_RS07475	COG0011	TIGRFAM Protein of
SAST43_RS07480	COG1940	carbohydrate kinase activity
SAST43_RS07485	COG4483	Protein conserved in bacteria
SAST43_RS07495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAST43_RS07505	COG0768	penicillin binding
SAST43_RS07520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAST43_RS07525	COG1121	(ABC) transporter
SAST43_RS07535	COG0513	Belongs to the DEAD box helicase family
SAST43_RS07545	COG2384	SAM-dependent methyltransferase
SAST43_RS07565	COG0517	IMP dehydrogenase activity
SAST43_RS07585	COG0295	cytidine deaminase activity
SAST43_RS07600	COG1702	phosphate starvation-inducible protein PhoH
SAST43_RS07615	COG1030	water channel activity
SAST43_RS07625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SAST43_RS07630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAST43_RS07660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAST43_RS07680	COG1466	dna polymerase III delta subunit
SAST43_RS07685	COG2333	competence protein COMEC
SAST43_RS07685	COG0658	competence protein
SAST43_RS07690	COG2131	deaminase
SAST43_RS07700	COG2226	methyltransferase
SAST43_RS07705	COG0799	negative regulation of ribosome biogenesis
SAST43_RS07710	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAST43_RS07720	COG1534	Rna-binding protein
SAST43_RS07730	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAST43_RS07735	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAST43_RS07760	COG1914	H( )-stimulated, divalent metal cation uptake system
SAST43_RS07770	COG0439	Biotin carboxylase
SAST43_RS07775	COG0511	ligase activity, forming carbon-carbon bonds
SAST43_RS07780	COG1984	allophanate hydrolase subunit 2
SAST43_RS07785	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SAST43_RS07800	COG0826	peptidase U32
SAST43_RS07805	COG0826	peptidase U32
SAST43_RS07835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAST43_RS07850	COG1104	cysteine desulfurase activity
SAST43_RS07855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAST43_RS07865	COG3237	CsbD-like
SAST43_RS07870	COG1959	2 iron, 2 sulfur cluster binding
SAST43_RS07875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAST43_RS07880	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SAST43_RS07925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAST43_RS07925	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAST43_RS07930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAST43_RS07930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAST43_RS07935	COG1862	Preprotein translocase
SAST43_RS07975	COG2868	ribosomal protein
SAST43_RS08015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SAST43_RS08025	COG0285	dihydrofolate synthase activity
SAST43_RS08035	COG2818	Glycosylase
SAST43_RS08070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SAST43_RS08105	COG4112	unkown
SAST43_RS08130	COG0833	amino acid
SAST43_RS08145	COG1484	DNA-dependent DNA replication
SAST43_RS08175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAST43_RS08175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAST43_RS08185	COG5002	protein histidine kinase activity
SAST43_RS08190	COG0745	RESPONSE REGULATOR receiver
SAST43_RS08205	COG0372	Belongs to the citrate synthase family
SAST43_RS08210	COG1113	amino acid transport
SAST43_RS08235	COG0281	malic enzyme
SAST43_RS08245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAST43_RS08250	COG4109	DRTGG domain
SAST43_RS08290	COG0827	DNA restriction-modification system
SAST43_RS08310	COG1104	cysteine desulfurase activity
SAST43_RS08325	COG1956	GAF domain-containing protein
SAST43_RS08340	COG0584	glycerophosphoryl diester phosphodiesterase
SAST43_RS08345	COG1764	response to oxidative stress
SAST43_RS08350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SAST43_RS08355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAST43_RS08370	COG1263	PTS System
SAST43_RS08370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAST43_RS08375	COG0204	Acyl-transferase
SAST43_RS08380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAST43_RS08415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAST43_RS08420	COG0454	-acetyltransferase
SAST43_RS08440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAST43_RS08440	COG1605	Chorismate mutase
SAST43_RS08465	COG1674	ftsk spoiiie
SAST43_RS08470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAST43_RS08480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAST43_RS08485	COG1363	Peptidase, m42
SAST43_RS08495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAST43_RS08505	COG0510	thiamine kinase activity
SAST43_RS08525	COG1187	pseudouridine synthase activity
SAST43_RS08530	COG2244	polysaccharide biosynthetic process
SAST43_RS08535	COG2081	HI0933 family
SAST43_RS08555	COG2814	Major facilitator Superfamily
SAST43_RS08560	COG1242	4 iron, 4 sulfur cluster binding
SAST43_RS08565	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAST43_RS08575	COG2267	carboxylic ester hydrolase activity
SAST43_RS08605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAST43_RS08605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAST43_RS08630	COG4193	domain, Protein
SAST43_RS08630	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAST43_RS08630	COG3266	domain, Protein
SAST43_RS08660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SAST43_RS08680	COG0656	L-ascorbic acid biosynthetic process
SAST43_RS08700	COG1506	peptidase
SAST43_RS08845	COG1131	(ABC) transporter
SAST43_RS08995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SAST43_RS09025	COG1131	(ABC) transporter
SAST43_RS09030	COG0537	adenosine 5'-monophosphoramidase activity
SAST43_RS09060	COG0420	3'-5' exonuclease activity
SAST43_RS09085	COG2197	response regulator
SAST43_RS09090	COG4585	Histidine kinase
SAST43_RS09090	COG2203	Gaf domain
SAST43_RS09095	COG0564	pseudouridine synthase activity
SAST43_RS09130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAST43_RS09135	COG1126	abc transporter atp-binding protein
SAST43_RS09140	COG0765	amino acid transport
SAST43_RS09295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAST43_RS09300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SAST43_RS09310	COG4129	membrane
SAST43_RS09335	COG1988	membrane-bound metal-dependent
SAST43_RS09350	COG1134	teichoic acid transport
SAST43_RS09350	COG1388	LysM domain
SAST43_RS09380	COG0535	radical SAM domain protein
SAST43_RS09385	COG1607	acyl-coa hydrolase
SAST43_RS09390	COG2309	aminopeptidase activity
SAST43_RS09410	COG1295	ribonuclease BN
SAST43_RS09525	COG4851	CamS sex pheromone cAM373 precursor
SAST43_RS09535	COG0210	DNA helicase
SAST43_RS09545	COG4496	protein, YerC YecD
SAST43_RS09580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAST43_RS09590	COG0077	Prephenate dehydratase
SAST43_RS09600	COG0471	metal ion transport
SAST43_RS09610	COG1335	isochorismatase
SAST43_RS09625	COG1012	belongs to the aldehyde dehydrogenase family
SAST43_RS09675	COG1131	(ABC) transporter
SAST43_RS09690	COG1725	Transcriptional regulator
SAST43_RS09750	COG1388	LysM domain
SAST43_RS09750	COG0860	N-Acetylmuramoyl-L-alanine amidase
SAST43_RS09760	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAST43_RS09760	COG1388	LysM domain
SAST43_RS09800	COG0739	heme binding
SAST43_RS09855	COG4695	Portal protein
SAST43_RS09970	COG1484	DNA-dependent DNA replication
SAST43_RS10050	COG3645	SOS response
SAST43_RS10050	COG3646	Phage regulatory protein
SAST43_RS10110	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAST43_RS10115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAST43_RS10120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAST43_RS10185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAST43_RS10190	COG1621	beta-fructofuranosidase activity
SAST43_RS10195	COG1609	Transcriptional regulator
SAST43_RS10200	COG0004	ammonium transporteR
SAST43_RS10205	COG0425	Belongs to the sulfur carrier protein TusA family
SAST43_RS10210	COG2391	methyltransferase activity
SAST43_RS10220	COG0488	(ABC) transporter
SAST43_RS10235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SAST43_RS10245	COG0456	acetyltransferase
SAST43_RS10250	COG1214	PFAM Peptidase M22, glycoprotease
SAST43_RS10255	COG0802	atpase or kinase
SAST43_RS10270	COG0028	Belongs to the TPP enzyme family
SAST43_RS10345	COG2183	response to ionizing radiation
SAST43_RS10350	COG1191	sigma factor activity
SAST43_RS10360	COG1366	Belongs to the anti-sigma-factor antagonist family
SAST43_RS10365	COG2208	phosphoserine phosphatase activity
SAST43_RS10400	COG3428	Bacterial PH domain
SAST43_RS10430	COG2205	protein histidine kinase activity
SAST43_RS10435	COG0745	RESPONSE REGULATOR receiver
SAST43_RS10445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAST43_RS10455	COG0772	Belongs to the SEDS family
SAST43_RS10470	COG1937	Protein conserved in bacteria
SAST43_RS10480	COG1418	mRNA catabolic process
SAST43_RS10515	COG0629	single-stranded DNA binding
SAST43_RS10590	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAST43_RS10615	COG0009	L-threonylcarbamoyladenylate synthase
SAST43_RS10620	COG2890	protein-(glutamine-N5) methyltransferase activity
SAST43_RS10640	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SAST43_RS10680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAST43_RS10730	COG0813	purine-nucleoside phosphorylase activity
SAST43_RS10735	COG0783	Belongs to the Dps family
SAST43_RS10755	COG1482	cell wall glycoprotein biosynthetic process
SAST43_RS10760	COG0702	epimerase
SAST43_RS10765	COG0640	Transcriptional regulator
SAST43_RS10785	COG0561	phosphatase activity
SAST43_RS10790	COG1119	ATPase activity
SAST43_RS10805	COG3711	transcriptional antiterminator
SAST43_RS10835	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAST43_RS10895	COG0489	protein tyrosine kinase activity
SAST43_RS10900	COG2814	Major facilitator Superfamily
SAST43_RS10915	COG1272	protein, Hemolysin III
SAST43_RS10925	COG1988	membrane-bound metal-dependent
SAST43_RS10935	COG3314	Sporulation integral membrane protein YlbJ
SAST43_RS10940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAST43_RS10945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAST43_RS10950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAST43_RS10960	COG3457	Alanine racemase
SAST43_RS10965	COG4264	IucA IucC family
SAST43_RS10970	COG2814	Major facilitator Superfamily
SAST43_RS10995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAST43_RS11005	COG2130	NADP-dependent
SAST43_RS11065	COG0656	L-ascorbic acid biosynthetic process
SAST43_RS11070	COG0789	Transcriptional regulator
SAST43_RS11080	COG5492	domain, Protein
SAST43_RS11130	COG3527	Alpha-acetolactate decarboxylase
SAST43_RS11135	COG0028	Belongs to the TPP enzyme family
SAST43_RS11145	COG0384	phenazine biosynthesis protein PhzF
SAST43_RS11215	COG0201	protein transport
SAST43_RS11330	COG2252	PERMEase
SAST43_RS11375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SAST43_RS11440	COG1763	Mo-molybdopterin cofactor biosynthetic process
SAST43_RS11460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SAST43_RS11465	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SAST43_RS11470	COG4149	molybdate abc transporter
SAST43_RS11475	COG0725	ABC transporter, periplasmic molybdate-binding protein
SAST43_RS11490	COG1268	BioY protein
SAST43_RS11505	COG1960	acyl-CoA dehydrogenase activity
SAST43_RS11510	COG4413	Urea transporter
SAST43_RS11575	COG3942	CHAP domain
SAST43_RS11585	COG1757	Na H antiporter
SAST43_RS11600	COG3942	CHAP domain
SAST43_RS11680	COG1113	amino acid transport
SAST43_RS11700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAST43_RS11705	COG0385	Bile acid
SAST43_RS11715	COG1263	PTS System
SAST43_RS11715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAST43_RS11720	COG1737	Transcriptional regulator
SAST43_RS11740	COG1028	Short-chain dehydrogenase reductase Sdr
SAST43_RS11745	COG1473	amidohydrolase
SAST43_RS11760	COG0583	DNA-binding transcription factor activity
SAST43_RS11785	COG2258	MOSC domain
SAST43_RS11805	COG1668	transmembrane transport
SAST43_RS11810	COG4152	abc transporter atp-binding protein
SAST43_RS11815	COG3152	Membrane
SAST43_RS11825	COG0786	glutamate:sodium symporter activity
SAST43_RS11835	COG0598	Magnesium transport protein CorA
SAST43_RS11850	COG0657	acetylesterase activity
SAST43_RS11860	COG2814	Major facilitator Superfamily
SAST43_RS11865	COG1566	PFAM secretion protein HlyD family protein
SAST43_RS11875	COG2814	Major facilitator Superfamily
SAST43_RS11940	COG1620	l-lactate permease
SAST43_RS11960	COG0604	alcohol dehydrogenase
SAST43_RS11990	COG1511	domain protein
SAST43_RS12005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAST43_RS12005	COG1263	PTS System
SAST43_RS12020	COG3871	stress protein (general stress protein 26)
SAST43_RS12070	COG2181	nitrate reductase activity
SAST43_RS12080	COG1140	nitrate reductase beta subunit
SAST43_RS12085	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SAST43_RS12095	COG2146	nitrite reductase [NAD(P)H] activity
SAST43_RS12100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAST43_RS12110	COG0454	-acetyltransferase
SAST43_RS12115	COG2116	formate transmembrane transporter activity
SAST43_RS12130	COG3443	Belongs to the bacterial solute-binding protein 9 family
SAST43_RS12130	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAST43_RS12165	COG1126	abc transporter atp-binding protein
SAST43_RS12170	COG0765	amino acid transport
SAST43_RS12175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAST43_RS12180	COG2814	Major facilitator Superfamily
SAST43_RS12195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAST43_RS12240	COG0156	8-amino-7-oxononanoate synthase activity
SAST43_RS12250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SAST43_RS12255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SAST43_RS12270	COG1132	(ABC) transporter
SAST43_RS12275	COG1132	(ABC) transporter
SAST43_RS12275	COG2375	cellular response to nickel ion
SAST43_RS12295	COG1929	Belongs to the glycerate kinase type-1 family
SAST43_RS12305	COG2814	Major facilitator Superfamily
SAST43_RS12325	COG1113	amino acid transport
SAST43_RS12335	COG0531	amino acid
SAST43_RS12360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAST43_RS12370	COG1174	glycine betaine transport
SAST43_RS12400	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SAST43_RS12405	COG0531	amino acid
SAST43_RS12410	COG2272	Belongs to the type-B carboxylesterase lipase family
SAST43_RS12415	COG2814	Major facilitator Superfamily
SAST43_RS12420	COG0390	transport system, permease component
SAST43_RS12425	COG4619	ABC transporter
SAST43_RS12430	COG1363	Peptidase, m42
SAST43_RS12450	COG4808	Protein conserved in bacteria
SAST43_RS12455	COG0069	glutamate synthase activity
SAST43_RS12470	COG1124	(ABC) transporter
SAST43_RS12480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAST43_RS12485	COG0601	transmembrane transport
SAST43_RS12515	COG1028	Short-chain dehydrogenase reductase Sdr
SAST43_RS12520	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SAST43_RS12525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAST43_RS12655	COG1070	Carbohydrate kinase
SAST43_RS12660	COG1802	Transcriptional regulator
SAST43_RS12665	COG0789	Transcriptional regulator
SAST43_RS12670	COG2357	RelA SpoT domain protein
SAST43_RS12675	COG4876	unkown
SAST43_RS12685	COG2271	Major facilitator Superfamily
SAST43_RS12690	COG0586	Pfam SNARE associated Golgi protein
SAST43_RS12700	COG1131	(ABC) transporter
SAST43_RS12715	COG3949	Membrane
SAST43_RS12720	COG0400	carboxylic ester hydrolase activity
SAST43_RS12725	COG0346	lactoylglutathione lyase activity
SAST43_RS12730	COG1846	Transcriptional regulator
SAST43_RS12740	COG2514	catechol 2,3-dioxygenase activity
SAST43_RS12755	COG0561	phosphatase activity
SAST43_RS12760	COG1131	(ABC) transporter
SAST43_RS12770	COG3764	Sortase (surface protein transpeptidase)
SAST43_RS12790	COG1760	l-serine dehydratase
SAST43_RS12795	COG1760	l-serine dehydratase
SAST43_RS12810	COG0697	spore germination
SAST43_RS12815	COG0657	acetylesterase activity
SAST43_RS12835	COG0028	Belongs to the TPP enzyme family
SAST43_RS12850	COG0583	DNA-binding transcription factor activity
SAST43_RS12860	COG3942	CHAP domain
SAST43_RS12880	COG1132	(ABC) transporter
SAST43_RS12885	COG1132	(ABC) transporter
SAST43_RS12915	COG3425	synthase
SAST43_RS12920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAST43_RS12945	COG2409	Drug exporters of the RND superfamily
SAST43_RS12990	COG0436	Aminotransferase
SAST43_RS13020	COG3942	CHAP domain
SAST43_RS13025	COG2755	lipolytic protein G-D-S-L family
SAST43_RS13025	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAST43_RS13030	COG2826	transposase and inactivated derivatives, IS30 family
SAST43_RS13055	COG5644	endopeptidase inhibitor activity
SAST43_RS13060	COG1674	ftsk spoiiie
SAST43_RS13070	COG0433	COG0433 Predicted ATPase
SAST43_RS13090	COG2946	Replication initiation factor
SAST43_RS13185	COG0596	Alpha beta hydrolase
SAST43_RS13220	COG3001	Fructosamine kinase
SAST43_RS13225	COG0167	dihydroorotate dehydrogenase activity
SAST43_RS13275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAST43_RS13280	COG3527	Alpha-acetolactate decarboxylase
SAST43_RS13295	COG0531	amino acid
SAST43_RS13325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAST43_RS13345	COG1012	belongs to the aldehyde dehydrogenase family
SAST43_RS13355	COG1510	regulation of RNA biosynthetic process
SAST43_RS13365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAST43_RS13390	COG2851	Citrate transporter
SAST43_RS13405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SAST43_RS13415	COG0386	Belongs to the glutathione peroxidase family
SAST43_RS13440	COG1136	(ABC) transporter
SAST43_RS13445	COG2205	protein histidine kinase activity
SAST43_RS13450	COG0745	RESPONSE REGULATOR receiver
SAST43_RS13465	COG1785	Belongs to the alkaline phosphatase family
SAST43_RS13470	COG1846	Transcriptional regulator
SAST43_RS13535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAST43_RS13535	COG3711	transcriptional antiterminator
SAST43_RS13540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAST43_RS13540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAST43_RS13540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAST43_RS13545	COG1482	cell wall glycoprotein biosynthetic process
SAST43_RS13555	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAST43_RS13555	COG3942	CHAP domain
SAST43_RS13560	COG3433	isochorismatase activity
SAST43_RS13560	COG1535	isochorismatase
SAST43_RS13575	COG0438	transferase activity, transferring glycosyl groups
SAST43_RS13590	COG1073	alpha beta
SAST43_RS13610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAST43_RS13630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAST43_RS13690	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SAST43_RS13720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SAST43_RS13780	COG0471	metal ion transport
SAST43_RS13785	COG2962	Rard protein
SAST43_RS13795	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SAST43_RS13810	COG1136	(ABC) transporter
SAST43_RS13815	COG0577	efflux transmembrane transporter activity
SAST43_RS13825	COG1278	Cold shock
SAST43_RS13845	COG1475	DNA binding