locus-tag	class	description
CFC57_RS00095	COG0583	DNA-binding transcription factor activity
CFC57_RS00180	COG1132	(ABC) transporter
CFC57_RS00230	COG2501	S4 domain
CFC57_RS00250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFC57_RS00275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFC57_RS00285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CFC57_RS00295	COG0305	Participates in initiation and elongation during chromosome replication
CFC57_RS00325	COG4863	YycH protein
CFC57_RS00335	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFC57_RS00340	COG0737	Belongs to the 5'-nucleotidase family
CFC57_RS00355	COG2801	Transposase and inactivated derivatives
CFC57_RS00385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFC57_RS00390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFC57_RS00395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFC57_RS00400	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CFC57_RS00415	COG0438	transferase activity, transferring glycosyl groups
CFC57_RS00465	COG2003	Belongs to the UPF0758 family
CFC57_RS00565	COG0730	response to heat
CFC57_RS00570	COG1937	Protein conserved in bacteria
CFC57_RS00575	COG2210	Belongs to the sulfur carrier protein TusA family
CFC57_RS00580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFC57_RS00615	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFC57_RS00630	COG0823	Involved in the tonB-independent uptake of proteins
CFC57_RS00655	COG1283	sodium-dependent phosphate transmembrane transporter activity
CFC57_RS00660	COG4716	Myosin-crossreactive antigen
CFC57_RS00665	COG0697	spore germination
CFC57_RS00680	COG1620	l-lactate permease
CFC57_RS00695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFC57_RS00700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFC57_RS00705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFC57_RS00715	COG2423	ornithine cyclodeaminase activity
CFC57_RS00720	COG4264	IucA IucC family
CFC57_RS00725	COG2814	Major facilitator Superfamily
CFC57_RS00730	COG4264	IucA IucC family
CFC57_RS00735	COG4264	IucA IucC family
CFC57_RS00745	COG0019	diaminopimelate decarboxylase activity
CFC57_RS00750	COG1475	DNA binding
CFC57_RS00780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFC57_RS00785	COG0438	transferase activity, transferring glycosyl groups
CFC57_RS00810	COG0813	purine-nucleoside phosphorylase activity
CFC57_RS00815	COG2814	Major facilitator Superfamily
CFC57_RS00835	COG3639	organic phosphonate transmembrane transporter activity
CFC57_RS00855	COG0737	Belongs to the 5'-nucleotidase family
CFC57_RS00870	COG1012	belongs to the aldehyde dehydrogenase family
CFC57_RS00870	COG1454	alcohol dehydrogenase
CFC57_RS00895	COG1086	Polysaccharide biosynthesis protein
CFC57_RS00905	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFC57_RS00935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFC57_RS00945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFC57_RS00950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFC57_RS00960	COG2832	Protein of unknown function (DUF454)
CFC57_RS00995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFC57_RS01000	COG1960	acyl-CoA dehydrogenase activity
CFC57_RS01020	COG3477	response to acidic pH
CFC57_RS01045	COG1114	Component of the transport system for branched-chain amino acids
CFC57_RS01050	COG1335	isochorismatase
CFC57_RS01055	COG3961	Belongs to the TPP enzyme family
CFC57_RS01085	COG1737	Transcriptional regulator
CFC57_RS01125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFC57_RS01135	COG0405	Gamma-glutamyltransferase
CFC57_RS01150	COG3842	ATPase activity
CFC57_RS01160	COG1175	transmembrane transport
CFC57_RS01165	COG3833	ABC-type maltose transport systems, permease component
CFC57_RS01170	COG0673	inositol 2-dehydrogenase activity
CFC57_RS01175	COG0673	inositol 2-dehydrogenase activity
CFC57_RS01185	COG1755	Isoprenylcysteine carboxyl methyltransferase
CFC57_RS01240	COG0183	Belongs to the thiolase family
CFC57_RS01250	COG1960	acyl-CoA dehydrogenase activity
CFC57_RS01255	COG0318	PFAM AMP-dependent synthetase and ligase
CFC57_RS01270	COG0747	negative chemotaxis
CFC57_RS01275	COG3189	MarR family transcriptional regulator
CFC57_RS01300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFC57_RS01300	COG1263	PTS System
CFC57_RS01300	COG2190	(PTS) system
CFC57_RS01305	COG1957	nucleoside hydrolase
CFC57_RS01325	COG3414	Phosphotransferase system galactitol-specific IIB component
CFC57_RS01330	COG3775	system Galactitol-specific IIC component
CFC57_RS01335	COG1063	alcohol dehydrogenase
CFC57_RS01345	COG1063	alcohol dehydrogenase
CFC57_RS01355	COG1063	alcohol dehydrogenase
CFC57_RS01360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CFC57_RS01365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CFC57_RS01375	COG1063	alcohol dehydrogenase
CFC57_RS01380	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CFC57_RS01420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFC57_RS01425	COG2190	(PTS) system
CFC57_RS01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFC57_RS01425	COG1263	PTS System
CFC57_RS01430	COG2723	6-phospho-beta-galactosidase activity
CFC57_RS01435	COG2226	methyltransferase
CFC57_RS01490	COG1131	(ABC) transporter
CFC57_RS01510	COG3942	CHAP domain
CFC57_RS01510	COG1388	LysM domain
CFC57_RS01610	COG1114	Component of the transport system for branched-chain amino acids
CFC57_RS01615	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CFC57_RS01620	COG0577	efflux transmembrane transporter activity
CFC57_RS01645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFC57_RS01650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFC57_RS01685	COG0582	viral genome integration into host DNA
CFC57_RS01715	COG3645	SOS response
CFC57_RS01715	COG3646	Phage regulatory protein
CFC57_RS01810	COG1484	DNA-dependent DNA replication
CFC57_RS01985	COG0739	heme binding
CFC57_RS02030	COG5632	N-Acetylmuramoyl-L-alanine amidase
CFC57_RS02030	COG1388	LysM domain
CFC57_RS02050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFC57_RS02075	COG3037	sugar-specific permease SgaT UlaA
CFC57_RS02085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFC57_RS02090	COG3711	transcriptional antiterminator
CFC57_RS02110	COG2271	Major facilitator Superfamily
CFC57_RS02115	COG0346	lactoylglutathione lyase activity
CFC57_RS02120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFC57_RS02125	COG0431	NADPH-dependent FMN reductase
CFC57_RS02135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFC57_RS02140	COG2822	iron ion transport
CFC57_RS02150	COG0672	)-iron permease
CFC57_RS02155	COG0805	protein transport
CFC57_RS02160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFC57_RS02170	COG1476	TRANSCRIPTIONal
CFC57_RS02180	COG1131	(ABC) transporter
CFC57_RS02210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CFC57_RS02210	COG0646	methionine synthase
CFC57_RS02215	COG0626	cystathionine gamma-synthase activity
CFC57_RS02220	COG0626	cystathionine gamma-synthase activity
CFC57_RS02225	COG1475	DNA binding
CFC57_RS02230	COG0668	transmembrane transport
CFC57_RS02235	COG4481	Protein conserved in bacteria
CFC57_RS02240	COG0012	GTP binding
CFC57_RS02340	COG1823	symporter activity
CFC57_RS02370	COG2233	PERMEase
CFC57_RS02405	COG3759	membrane
CFC57_RS02465	COG2946	Replication initiation factor
CFC57_RS02485	COG0433	COG0433 Predicted ATPase
CFC57_RS02500	COG1674	ftsk spoiiie
CFC57_RS02530	COG2826	transposase and inactivated derivatives, IS30 family
CFC57_RS02635	COG0523	cobalamin synthesis protein
CFC57_RS02660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFC57_RS02670	COG5609	conserved protein (DUF2294)
CFC57_RS02685	COG1647	Serine aminopeptidase, S33
CFC57_RS02695	COG0733	neurotransmitter:sodium symporter activity
CFC57_RS02700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFC57_RS02705	COG0626	cystathionine gamma-synthase activity
CFC57_RS02715	COG2011	ABC-type metal ion transport system permease component
CFC57_RS02720	COG1464	Belongs to the NlpA lipoprotein family
CFC57_RS02755	COG0583	DNA-binding transcription factor activity
CFC57_RS02760	COG0070	glutamate synthase
CFC57_RS02760	COG0069	glutamate synthase activity
CFC57_RS02760	COG0067	glutamate synthase
CFC57_RS02765	COG0493	'glutamate synthase
CFC57_RS02775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFC57_RS02775	COG1263	PTS System
CFC57_RS02780	COG0366	Alpha amylase catalytic
CFC57_RS02785	COG2188	Transcriptional regulator
CFC57_RS02805	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFC57_RS02840	COG1982	Orn Lys Arg decarboxylase major
CFC57_RS02850	COG3870	Protein conserved in bacteria
CFC57_RS02855	COG0470	DNA polymerase III
CFC57_RS02860	COG1774	PSP1 C-terminal conserved region
CFC57_RS02870	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CFC57_RS02880	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFC57_RS02890	COG0084	hydrolase, TatD family'
CFC57_RS02895	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CFC57_RS02905	COG4466	Protein conserved in bacteria
CFC57_RS02915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFC57_RS02920	COG0251	oxidation-reduction process
CFC57_RS02960	COG2244	polysaccharide biosynthetic process
CFC57_RS02965	COG3956	TIGRFAM MazG family protein
CFC57_RS02970	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CFC57_RS02980	COG1098	S1 RNA binding domain
CFC57_RS02995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFC57_RS03020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFC57_RS03115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFC57_RS03130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFC57_RS03140	COG3880	PFAM UvrB UvrC protein
CFC57_RS03155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CFC57_RS03160	COG4956	integral membrane protein (PIN domain superfamily)
CFC57_RS03180	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CFC57_RS03235	COG2813	Specifically methylates the guanine in position
CFC57_RS03275	COG1473	amidohydrolase
CFC57_RS03305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CFC57_RS03310	COG1428	Deoxynucleoside kinase
CFC57_RS03315	COG1428	Deoxynucleoside kinase
CFC57_RS03325	COG0561	phosphatase activity
CFC57_RS03355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CFC57_RS03460	COG0095	Lipoate-protein ligase
CFC57_RS03465	COG0083	homoserine kinase activity
CFC57_RS03485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFC57_RS03530	COG0667	Aldo Keto reductase
CFC57_RS03535	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFC57_RS03545	COG1078	dGTPase activity
CFC57_RS03580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFC57_RS03585	COG4139	cobalamin transport
CFC57_RS03635	COG4974	Belongs to the 'phage' integrase family
CFC57_RS03680	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFC57_RS03685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFC57_RS03690	COG1121	(ABC) transporter
CFC57_RS03695	COG1321	iron dependent repressor
CFC57_RS03705	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CFC57_RS03715	COG1682	transport, permease protein
CFC57_RS03720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CFC57_RS03730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CFC57_RS03735	COG1686	Belongs to the peptidase S11 family
CFC57_RS03740	COG1132	(ABC) transporter
CFC57_RS03745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFC57_RS03755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFC57_RS03760	COG1120	ATPase activity
CFC57_RS03765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFC57_RS03770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFC57_RS03775	COG2376	Dihydroxyacetone kinase
CFC57_RS03785	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CFC57_RS03795	COG3949	Membrane
CFC57_RS03815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFC57_RS03830	COG1136	(ABC) transporter
CFC57_RS03835	COG0577	efflux transmembrane transporter activity
CFC57_RS03840	COG1392	Phosphate transport regulator
CFC57_RS03850	COG3942	CHAP domain
CFC57_RS03850	COG1388	LysM domain
CFC57_RS03860	COG4977	sequence-specific DNA binding
CFC57_RS03860	COG1917	Cupin 2, conserved barrel domain protein
CFC57_RS03890	COG0583	DNA-binding transcription factor activity
CFC57_RS03900	COG2839	Protein conserved in bacteria
CFC57_RS03930	COG1611	Belongs to the LOG family
CFC57_RS03950	COG4988	ABC transporter
CFC57_RS03955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFC57_RS03965	COG0523	cobalamin synthesis protein
CFC57_RS03970	COG4989	oxidoreductase activity
CFC57_RS03980	COG0471	metal ion transport
CFC57_RS04015	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFC57_RS04020	COG1349	DNA-binding transcription factor activity
CFC57_RS04025	COG1105	Belongs to the carbohydrate kinase PfkB family
CFC57_RS04030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFC57_RS04030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFC57_RS04030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFC57_RS04035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFC57_RS04040	COG1253	flavin adenine dinucleotide binding
CFC57_RS04045	COG0656	L-ascorbic acid biosynthetic process
CFC57_RS04050	COG0463	Glycosyl transferase, family 2
CFC57_RS04085	COG0720	synthase
CFC57_RS04095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFC57_RS04095	COG0512	Glutamine amidotransferase of anthranilate synthase
CFC57_RS04100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFC57_RS04130	COG0488	(ABC) transporter
CFC57_RS04135	COG0514	ATP-dependent DNA helicase (RecQ)
CFC57_RS04140	COG1125	glycine betaine transport
CFC57_RS04140	COG0517	IMP dehydrogenase activity
CFC57_RS04145	COG1174	glycine betaine transport
CFC57_RS04165	COG3104	oligopeptide transport
CFC57_RS04185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFC57_RS04190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFC57_RS04200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFC57_RS04205	COG4605	iron ion homeostasis
CFC57_RS04210	COG4604	ABC transporter, ATP-binding protein
CFC57_RS04215	COG4607	ABC-type enterochelin transport system periplasmic component
CFC57_RS04270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFC57_RS04275	COG1739	Uncharacterized protein family UPF0029
CFC57_RS04285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CFC57_RS04290	COG1040	competence protein
CFC57_RS04320	COG1388	LysM domain
CFC57_RS04320	COG3942	CHAP domain
CFC57_RS04375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CFC57_RS04390	COG0281	malic enzyme
CFC57_RS04440	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFC57_RS04445	COG1647	Serine aminopeptidase, S33
CFC57_RS04450	COG0557	exoribonuclease II activity
CFC57_RS04510	COG1278	Cold shock
CFC57_RS04550	COG0406	alpha-ribazole phosphatase activity
CFC57_RS04555	COG1279	arginine transmembrane transporter activity
CFC57_RS04580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFC57_RS04585	COG1393	Belongs to the ArsC family
CFC57_RS04600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CFC57_RS04615	COG2011	ABC-type metal ion transport system permease component
CFC57_RS04620	COG1464	Belongs to the NlpA lipoprotein family
CFC57_RS04770	COG0396	ATPase activity
CFC57_RS04775	COG0719	Fe-S assembly protein
CFC57_RS04785	COG0822	iron-sulfur transferase activity
CFC57_RS04800	COG1253	flavin adenine dinucleotide binding
CFC57_RS04810	COG1801	Protein of unknown function DUF72
CFC57_RS04815	COG0730	response to heat
CFC57_RS04830	COG4470	Protein conserved in bacteria
CFC57_RS04840	COG2445	Protein of unknown function DUF86
CFC57_RS04870	COG1696	Membrane protein involved in D-alanine export
CFC57_RS04880	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CFC57_RS04885	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFC57_RS04890	COG4837	Protein of unknown function (DUF1462)
CFC57_RS04895	COG1252	NADH dehydrogenase
CFC57_RS04905	COG0316	Belongs to the HesB IscA family
CFC57_RS04915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFC57_RS04920	COG2056	Na+-H+ antiporter family
CFC57_RS04925	COG2050	protein possibly involved in aromatic compounds catabolism
CFC57_RS04980	COG1098	S1 RNA binding domain
CFC57_RS04985	COG1902	pentaerythritol trinitrate reductase activity
CFC57_RS05000	COG0584	glycerophosphoryl diester phosphodiesterase
CFC57_RS05020	COG0398	Pfam SNARE associated Golgi protein
CFC57_RS05060	COG0561	phosphatase activity
CFC57_RS05125	COG0601	transmembrane transport
CFC57_RS05130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFC57_RS05135	COG0444	Belongs to the ABC transporter superfamily
CFC57_RS05140	COG4608	Belongs to the ABC transporter superfamily
CFC57_RS05145	COG4166	transmembrane transport
CFC57_RS05150	COG0747	negative chemotaxis
CFC57_RS05155	COG0444	Belongs to the ABC transporter superfamily
CFC57_RS05160	COG4608	Belongs to the ABC transporter superfamily
CFC57_RS05165	COG0601	transmembrane transport
CFC57_RS05170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFC57_RS05195	COG1164	Oligoendopeptidase f
CFC57_RS05205	COG2346	COG2346, Truncated hemoglobins
CFC57_RS05220	COG2357	RelA SpoT domain protein
CFC57_RS05230	COG0564	pseudouridine synthase activity
CFC57_RS05235	COG2239	Acts as a magnesium transporter
CFC57_RS05240	COG0569	domain protein
CFC57_RS05240	COG0475	glutathione-regulated potassium exporter activity
CFC57_RS05250	COG0628	permease
CFC57_RS05255	COG1115	amino acid carrier protein
CFC57_RS05295	COG0861	Integral membrane protein TerC family
CFC57_RS05305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFC57_RS05310	COG0737	Belongs to the 5'-nucleotidase family
CFC57_RS05325	COG4903	ComK protein
CFC57_RS05340	COG4873	Protein conserved in bacteria
CFC57_RS05390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CFC57_RS05400	COG2314	TM2 domain
CFC57_RS05410	COG1575	Belongs to the MenA family. Type 1 subfamily
CFC57_RS05415	COG1169	isochorismate synthase
CFC57_RS05425	COG2267	carboxylic ester hydrolase activity
CFC57_RS05450	COG0436	Aminotransferase
CFC57_RS05455	COG3594	Acyltransferase
CFC57_RS05485	COG1316	TRANSCRIPTIONal
CFC57_RS05530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFC57_RS05545	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFC57_RS05585	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFC57_RS05590	COG4172	Belongs to the ABC transporter superfamily
CFC57_RS05595	COG4721	ABC-type cobalt transport system, permease component
CFC57_RS05610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CFC57_RS05630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFC57_RS05635	COG1271	oxidase subunit
CFC57_RS05640	COG1294	oxidase, subunit
CFC57_RS05645	COG0569	domain protein
CFC57_RS05710	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFC57_RS05715	COG1177	transmembrane transport
CFC57_RS05720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CFC57_RS05745	COG0483	inositol monophosphate 1-phosphatase activity
CFC57_RS05765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFC57_RS05775	COG0772	Belongs to the SEDS family
CFC57_RS05805	COG3679	Belongs to the UPF0342 family
CFC57_RS05825	COG0742	ribosomal rna small subunit methyltransferase
CFC57_RS05880	COG4509	Sortase family
CFC57_RS05895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFC57_RS05925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CFC57_RS05925	COG1796	DNA polymerase
CFC57_RS05950	COG2009	succinate dehydrogenase
CFC57_RS05955	COG1053	succinate dehydrogenase
CFC57_RS05960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFC57_RS06065	COG1288	antiporter activity
CFC57_RS06100	COG1011	Hydrolase
CFC57_RS06125	COG4839	cell division protein FtsL
CFC57_RS06150	COG0849	cell division
CFC57_RS06165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFC57_RS06175	COG0762	integral membrane protein
CFC57_RS06180	COG2302	S4 RNA-binding domain
CFC57_RS06185	COG3599	regulation of cell shape
CFC57_RS06195	COG2514	catechol 2,3-dioxygenase activity
CFC57_RS06210	COG0564	pseudouridine synthase activity
CFC57_RS06220	COG2233	PERMEase
CFC57_RS06265	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CFC57_RS06280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFC57_RS06285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFC57_RS06295	COG2314	TM2 domain
CFC57_RS06310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFC57_RS06310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFC57_RS06320	COG0631	protein serine/threonine phosphatase activity
CFC57_RS06335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CFC57_RS06350	COG1302	Protein conserved in bacteria
CFC57_RS06395	COG1196	nuclear chromosome segregation
CFC57_RS06400	COG0552	protein localization to endoplasmic reticulum
CFC57_RS06410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFC57_RS06440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CFC57_RS06465	COG2348	transferase activity, transferring amino-acyl groups
CFC57_RS06565	COG0195	Participates in both transcription termination and antitermination
CFC57_RS06570	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CFC57_RS06595	COG0196	riboflavin kinase activity
CFC57_RS06620	COG2188	Transcriptional regulator
CFC57_RS06625	COG0612	Peptidase, M16
CFC57_RS06630	COG0612	Peptidase, M16
CFC57_RS06635	COG0300	oxidoreductase activity
CFC57_RS06655	COG1546	Belongs to the CinA family
CFC57_RS06655	COG1058	Belongs to the CinA family
CFC57_RS06675	COG1692	metallophosphoesterase
CFC57_RS06680	COG0674	pyruvate-flavodoxin oxidoreductase activity
CFC57_RS06680	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CFC57_RS06685	COG1013	pyruvate-flavodoxin oxidoreductase activity
CFC57_RS06720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CFC57_RS06725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFC57_RS06750	COG1923	regulation of RNA biosynthetic process
CFC57_RS06760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFC57_RS06765	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CFC57_RS06770	COG0789	Transcriptional regulator
CFC57_RS06840	COG1525	nuclease
CFC57_RS06855	COG0527	aspartate kinase activity
CFC57_RS06860	COG0460	homoserine dehydrogenase
CFC57_RS06865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CFC57_RS06890	COG0833	amino acid
CFC57_RS06915	COG2340	Cysteine-rich secretory protein family
CFC57_RS06950	COG4846	Membrane protein involved in cytochrome C biogenesis
CFC57_RS06970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFC57_RS06980	COG0824	Thioesterase
CFC57_RS07000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFC57_RS07005	COG1115	amino acid carrier protein
CFC57_RS07020	COG0628	permease
CFC57_RS07055	COG1363	Peptidase, m42
CFC57_RS07060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFC57_RS07065	COG0512	Glutamine amidotransferase of anthranilate synthase
CFC57_RS07105	COG0561	phosphatase activity
CFC57_RS07150	COG0704	Plays a role in the regulation of phosphate uptake
CFC57_RS07160	COG0581	inorganic phosphate transmembrane transporter activity
CFC57_RS07165	COG0573	inorganic phosphate transmembrane transporter activity
CFC57_RS07180	COG0488	(ABC) transporter
CFC57_RS07185	COG0527	aspartate kinase activity
CFC57_RS07190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFC57_RS07225	COG2808	Putative FMN-binding domain
CFC57_RS07265	COG4548	von Willebrand factor, type A
CFC57_RS07270	COG0714	Associated with various cellular activities
CFC57_RS07315	COG0671	phosphoesterase, PA-phosphatase related
CFC57_RS07390	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFC57_RS07410	COG0531	amino acid
CFC57_RS07425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFC57_RS07430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CFC57_RS07445	COG0116	Belongs to the methyltransferase superfamily
CFC57_RS07475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFC57_RS07475	COG4499	WXG100 protein secretion system (Wss), protein YukC
CFC57_RS07485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFC57_RS07490	COG3935	DnaD domain protein
CFC57_RS07515	COG0438	transferase activity, transferring glycosyl groups
CFC57_RS07520	COG1694	Mazg nucleotide pyrophosphohydrolase
CFC57_RS07525	COG2738	Putative neutral zinc metallopeptidase
CFC57_RS07530	COG4347	Protein of unknown function (DUF1405)
CFC57_RS07565	COG0142	geranyltranstransferase activity
CFC57_RS07620	COG0492	ferredoxin-NADP+ reductase activity
CFC57_RS07635	COG0514	ATP-dependent DNA helicase (RecQ)
CFC57_RS07645	COG1141	Ferredoxin
CFC57_RS07675	COG5002	protein histidine kinase activity
CFC57_RS07680	COG0745	RESPONSE REGULATOR receiver
CFC57_RS07685	COG1187	pseudouridine synthase activity
CFC57_RS07710	COG0735	belongs to the Fur family
CFC57_RS07715	COG0494	nUDIX hydrolase
CFC57_RS07720	COG0667	Aldo Keto reductase
CFC57_RS07745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFC57_RS07755	COG0366	Alpha amylase catalytic
CFC57_RS07760	COG1609	Transcriptional regulator
CFC57_RS07790	COG2195	Cleaves the N-terminal amino acid of tripeptides
CFC57_RS07800	COG4129	membrane
CFC57_RS07810	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFC57_RS07815	COG0022	dehydrogenase e1 component
CFC57_RS07820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFC57_RS07825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFC57_RS07830	COG0497	DNA recombination
CFC57_RS07860	COG1302	Protein conserved in bacteria
CFC57_RS07865	COG0439	Biotin carboxylase
CFC57_RS07870	COG0511	ligase activity, forming carbon-carbon bonds
CFC57_RS07880	COG0006	proline dipeptidase activity
CFC57_RS07895	COG0095	Lipoate-protein ligase
CFC57_RS07900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFC57_RS07945	COG4537	Required for transformation and DNA binding
CFC57_RS07955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFC57_RS07960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFC57_RS07965	COG0011	TIGRFAM Protein of
CFC57_RS07970	COG1940	carbohydrate kinase activity
CFC57_RS07975	COG4483	Protein conserved in bacteria
CFC57_RS07985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFC57_RS08010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFC57_RS08015	COG1121	(ABC) transporter
CFC57_RS08025	COG0513	Belongs to the DEAD box helicase family
CFC57_RS08035	COG2384	SAM-dependent methyltransferase
CFC57_RS08055	COG0517	IMP dehydrogenase activity
CFC57_RS08075	COG0295	cytidine deaminase activity
CFC57_RS08080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CFC57_RS08090	COG1702	phosphate starvation-inducible protein PhoH
CFC57_RS08105	COG1030	water channel activity
CFC57_RS08115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFC57_RS08120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFC57_RS08150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFC57_RS08165	COG1466	dna polymerase III delta subunit
CFC57_RS08170	COG2333	competence protein COMEC
CFC57_RS08170	COG0658	competence protein
CFC57_RS08175	COG2131	deaminase
CFC57_RS08185	COG2226	methyltransferase
CFC57_RS08190	COG0799	negative regulation of ribosome biogenesis
CFC57_RS08195	COG1713	HD superfamily hydrolase involved in NAD metabolism
CFC57_RS08205	COG1534	Rna-binding protein
CFC57_RS08215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CFC57_RS08220	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CFC57_RS08240	COG3177	Filamentation induced by cAMP protein fic
CFC57_RS08245	COG1914	H( )-stimulated, divalent metal cation uptake system
CFC57_RS08255	COG0439	Biotin carboxylase
CFC57_RS08260	COG0511	ligase activity, forming carbon-carbon bonds
CFC57_RS08265	COG1984	allophanate hydrolase subunit 2
CFC57_RS08270	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFC57_RS08320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFC57_RS08335	COG1104	cysteine desulfurase activity
CFC57_RS08340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFC57_RS08350	COG3237	CsbD-like
CFC57_RS08355	COG1959	2 iron, 2 sulfur cluster binding
CFC57_RS08360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFC57_RS08365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CFC57_RS08410	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CFC57_RS08410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFC57_RS08415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFC57_RS08415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFC57_RS08420	COG1862	Preprotein translocase
CFC57_RS08460	COG2868	ribosomal protein
CFC57_RS08505	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CFC57_RS08510	COG0285	dihydrofolate synthase activity
CFC57_RS08520	COG2818	Glycosylase
CFC57_RS08555	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFC57_RS08590	COG4112	unkown
CFC57_RS08610	COG0833	amino acid
CFC57_RS08625	COG1484	DNA-dependent DNA replication
CFC57_RS08655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFC57_RS08655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFC57_RS08665	COG5002	protein histidine kinase activity
CFC57_RS08670	COG0745	RESPONSE REGULATOR receiver
CFC57_RS08680	COG0372	Belongs to the citrate synthase family
CFC57_RS08685	COG1113	amino acid transport
CFC57_RS08710	COG0281	malic enzyme
CFC57_RS08720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CFC57_RS08725	COG4109	DRTGG domain
CFC57_RS08765	COG0827	DNA restriction-modification system
CFC57_RS08775	COG0730	response to heat
CFC57_RS08785	COG1104	cysteine desulfurase activity
CFC57_RS08795	COG1956	GAF domain-containing protein
CFC57_RS08805	COG0584	glycerophosphoryl diester phosphodiesterase
CFC57_RS08810	COG1764	response to oxidative stress
CFC57_RS08815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFC57_RS08820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFC57_RS08835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFC57_RS08835	COG1263	PTS System
CFC57_RS08840	COG0204	Acyl-transferase
CFC57_RS08845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFC57_RS08880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFC57_RS08885	COG0454	-acetyltransferase
CFC57_RS08905	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CFC57_RS08905	COG1605	Chorismate mutase
CFC57_RS08930	COG1674	ftsk spoiiie
CFC57_RS08935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFC57_RS08945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFC57_RS08950	COG1363	Peptidase, m42
CFC57_RS08960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFC57_RS08970	COG0510	thiamine kinase activity
CFC57_RS08990	COG1187	pseudouridine synthase activity
CFC57_RS08995	COG2244	polysaccharide biosynthetic process
CFC57_RS09000	COG2081	HI0933 family
CFC57_RS09020	COG2814	Major facilitator Superfamily
CFC57_RS09025	COG1242	4 iron, 4 sulfur cluster binding
CFC57_RS09030	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CFC57_RS09040	COG2267	carboxylic ester hydrolase activity
CFC57_RS09070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFC57_RS09070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFC57_RS09095	COG4193	domain, Protein
CFC57_RS09095	COG3266	domain, Protein
CFC57_RS09095	COG5632	N-Acetylmuramoyl-L-alanine amidase
CFC57_RS09125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFC57_RS09145	COG0656	L-ascorbic acid biosynthetic process
CFC57_RS09165	COG1506	peptidase
CFC57_RS09170	COG2816	NAD+ diphosphatase activity
CFC57_RS09425	COG1131	(ABC) transporter
CFC57_RS09430	COG0537	adenosine 5'-monophosphoramidase activity
CFC57_RS09440	COG2826	transposase and inactivated derivatives, IS30 family
CFC57_RS09465	COG5644	endopeptidase inhibitor activity
CFC57_RS09475	COG1674	ftsk spoiiie
CFC57_RS09485	COG0433	COG0433 Predicted ATPase
CFC57_RS09505	COG2946	Replication initiation factor
CFC57_RS09555	COG1388	LysM domain
CFC57_RS09555	COG5632	N-Acetylmuramoyl-L-alanine amidase
CFC57_RS09765	COG1484	DNA-dependent DNA replication
CFC57_RS09855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFC57_RS09905	COG0420	3'-5' exonuclease activity
CFC57_RS09925	COG2197	response regulator
CFC57_RS09930	COG2203	Gaf domain
CFC57_RS09930	COG4585	Histidine kinase
CFC57_RS09935	COG0564	pseudouridine synthase activity
CFC57_RS09965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFC57_RS09970	COG1126	abc transporter atp-binding protein
CFC57_RS09975	COG0765	amino acid transport
CFC57_RS10150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFC57_RS10155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFC57_RS10165	COG4129	membrane
CFC57_RS10185	COG1194	a g-specific adenine glycosylase
CFC57_RS10190	COG1988	membrane-bound metal-dependent
CFC57_RS10200	COG1134	teichoic acid transport
CFC57_RS10200	COG1388	LysM domain
CFC57_RS10230	COG0535	radical SAM domain protein
CFC57_RS10235	COG1607	acyl-coa hydrolase
CFC57_RS10240	COG2309	aminopeptidase activity
CFC57_RS10260	COG1295	ribonuclease BN
CFC57_RS10265	COG2197	response regulator
CFC57_RS10375	COG1733	regulation of RNA biosynthetic process
CFC57_RS10385	COG4851	CamS sex pheromone cAM373 precursor
CFC57_RS10405	COG4496	protein, YerC YecD
CFC57_RS10440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFC57_RS10450	COG0077	Prephenate dehydratase
CFC57_RS10470	COG1335	isochorismatase
CFC57_RS10485	COG1012	belongs to the aldehyde dehydrogenase family
CFC57_RS10535	COG1131	(ABC) transporter
CFC57_RS10550	COG1725	Transcriptional regulator
CFC57_RS10610	COG1388	LysM domain
CFC57_RS10610	COG5632	N-Acetylmuramoyl-L-alanine amidase
CFC57_RS10890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFC57_RS10945	COG0156	8-amino-7-oxononanoate synthase activity
CFC57_RS10950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFC57_RS11075	COG0582	viral genome integration into host DNA
CFC57_RS11140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFC57_RS11145	COG1621	beta-fructofuranosidase activity
CFC57_RS11150	COG1609	Transcriptional regulator
CFC57_RS11155	COG0004	ammonium transporteR
CFC57_RS11160	COG0425	Belongs to the sulfur carrier protein TusA family
CFC57_RS11165	COG2391	methyltransferase activity
CFC57_RS11175	COG0488	(ABC) transporter
CFC57_RS11190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFC57_RS11200	COG0456	acetyltransferase
CFC57_RS11205	COG1214	PFAM Peptidase M22, glycoprotease
CFC57_RS11210	COG0802	atpase or kinase
CFC57_RS11225	COG0028	Belongs to the TPP enzyme family
CFC57_RS11295	COG2183	response to ionizing radiation
CFC57_RS11300	COG1191	sigma factor activity
CFC57_RS11310	COG1366	Belongs to the anti-sigma-factor antagonist family
CFC57_RS11315	COG2208	phosphoserine phosphatase activity
CFC57_RS11345	COG3428	Bacterial PH domain
CFC57_RS11375	COG2205	protein histidine kinase activity
CFC57_RS11380	COG0745	RESPONSE REGULATOR receiver
CFC57_RS11390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFC57_RS11400	COG0772	Belongs to the SEDS family
CFC57_RS11415	COG1937	Protein conserved in bacteria
CFC57_RS11425	COG1418	mRNA catabolic process
CFC57_RS11460	COG0629	single-stranded DNA binding
CFC57_RS11530	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFC57_RS11555	COG0009	L-threonylcarbamoyladenylate synthase
CFC57_RS11560	COG2890	protein-(glutamine-N5) methyltransferase activity
CFC57_RS11580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFC57_RS11620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFC57_RS11665	COG0813	purine-nucleoside phosphorylase activity
CFC57_RS11670	COG0783	Belongs to the Dps family
CFC57_RS11690	COG1482	cell wall glycoprotein biosynthetic process
CFC57_RS11695	COG0702	epimerase
CFC57_RS11700	COG0640	Transcriptional regulator
CFC57_RS11720	COG0561	phosphatase activity
CFC57_RS11725	COG1119	ATPase activity
CFC57_RS11740	COG3711	transcriptional antiterminator
CFC57_RS11770	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CFC57_RS11825	COG0489	protein tyrosine kinase activity
CFC57_RS11830	COG2814	Major facilitator Superfamily
CFC57_RS11845	COG1272	protein, Hemolysin III
CFC57_RS11855	COG1988	membrane-bound metal-dependent
CFC57_RS11870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFC57_RS11875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFC57_RS11880	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CFC57_RS11890	COG3457	Alanine racemase
CFC57_RS11895	COG4264	IucA IucC family
CFC57_RS11925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFC57_RS11935	COG2130	NADP-dependent
CFC57_RS12000	COG0656	L-ascorbic acid biosynthetic process
CFC57_RS12005	COG0789	Transcriptional regulator
CFC57_RS12015	COG5492	domain, Protein
CFC57_RS12020	COG2378	regulation of single-species biofilm formation
CFC57_RS12025	COG0693	protein deglycase activity
CFC57_RS12035	COG3527	Alpha-acetolactate decarboxylase
CFC57_RS12040	COG0028	Belongs to the TPP enzyme family
CFC57_RS12125	COG0201	protein transport
CFC57_RS12240	COG2252	PERMEase
CFC57_RS12285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFC57_RS12345	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFC57_RS12365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CFC57_RS12370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFC57_RS12375	COG4149	molybdate abc transporter
CFC57_RS12380	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFC57_RS12395	COG1268	BioY protein
CFC57_RS12410	COG1960	acyl-CoA dehydrogenase activity
CFC57_RS12415	COG4413	Urea transporter
CFC57_RS12485	COG1757	Na H antiporter
CFC57_RS12500	COG3942	CHAP domain
CFC57_RS12565	COG1113	amino acid transport
CFC57_RS12585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFC57_RS12590	COG0385	Bile acid
CFC57_RS12600	COG1263	PTS System
CFC57_RS12600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFC57_RS12605	COG1737	Transcriptional regulator
CFC57_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
CFC57_RS12630	COG1473	amidohydrolase
CFC57_RS12645	COG0583	DNA-binding transcription factor activity
CFC57_RS12665	COG2258	MOSC domain
CFC57_RS12685	COG1668	transmembrane transport
CFC57_RS12690	COG4152	abc transporter atp-binding protein
CFC57_RS12695	COG3152	Membrane
CFC57_RS12705	COG0786	glutamate:sodium symporter activity
CFC57_RS12715	COG0598	Magnesium transport protein CorA
CFC57_RS12730	COG0657	acetylesterase activity
CFC57_RS12740	COG2814	Major facilitator Superfamily
CFC57_RS12745	COG1566	PFAM secretion protein HlyD family protein
CFC57_RS12755	COG2814	Major facilitator Superfamily
CFC57_RS12820	COG1131	(ABC) transporter
CFC57_RS12835	COG1620	l-lactate permease
CFC57_RS12855	COG0604	alcohol dehydrogenase
CFC57_RS12880	COG1511	domain protein
CFC57_RS12895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFC57_RS12895	COG1263	PTS System
CFC57_RS12910	COG3871	stress protein (general stress protein 26)
CFC57_RS12960	COG2181	nitrate reductase activity
CFC57_RS12970	COG1140	nitrate reductase beta subunit
CFC57_RS12975	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFC57_RS12985	COG2146	nitrite reductase [NAD(P)H] activity
CFC57_RS12990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFC57_RS13000	COG0454	-acetyltransferase
CFC57_RS13005	COG2116	formate transmembrane transporter activity
CFC57_RS13020	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFC57_RS13020	COG3443	Belongs to the bacterial solute-binding protein 9 family
CFC57_RS13055	COG1126	abc transporter atp-binding protein
CFC57_RS13060	COG0765	amino acid transport
CFC57_RS13065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFC57_RS13070	COG2814	Major facilitator Superfamily
CFC57_RS13085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFC57_RS13125	COG0156	8-amino-7-oxononanoate synthase activity
CFC57_RS13135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFC57_RS13140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFC57_RS13150	COG1132	(ABC) transporter
CFC57_RS13170	COG1929	Belongs to the glycerate kinase type-1 family
CFC57_RS13180	COG2814	Major facilitator Superfamily
CFC57_RS13195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFC57_RS13200	COG1113	amino acid transport
CFC57_RS13210	COG0531	amino acid
CFC57_RS13225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFC57_RS13235	COG1174	glycine betaine transport
CFC57_RS13245	COG1174	glycine betaine transport
CFC57_RS13265	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CFC57_RS13270	COG0531	amino acid
CFC57_RS13275	COG2272	Belongs to the type-B carboxylesterase lipase family
CFC57_RS13280	COG2814	Major facilitator Superfamily
CFC57_RS13285	COG0390	transport system, permease component
CFC57_RS13290	COG4619	ABC transporter
CFC57_RS13295	COG1363	Peptidase, m42
CFC57_RS13310	COG4808	Protein conserved in bacteria
CFC57_RS13315	COG0069	glutamate synthase activity
CFC57_RS13330	COG1124	(ABC) transporter
CFC57_RS13340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFC57_RS13345	COG0601	transmembrane transport
CFC57_RS13350	COG0747	negative chemotaxis
CFC57_RS13370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFC57_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
CFC57_RS13380	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CFC57_RS13385	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFC57_RS13455	COG0494	nUDIX hydrolase
CFC57_RS13500	COG1070	Carbohydrate kinase
CFC57_RS13505	COG1802	Transcriptional regulator
CFC57_RS13510	COG0789	Transcriptional regulator
CFC57_RS13515	COG2357	RelA SpoT domain protein
CFC57_RS13520	COG4876	unkown
CFC57_RS13530	COG2271	Major facilitator Superfamily
CFC57_RS13535	COG0586	Pfam SNARE associated Golgi protein
CFC57_RS13545	COG2814	Major facilitator Superfamily
CFC57_RS13550	COG1846	Transcriptional regulator
CFC57_RS13555	COG1131	(ABC) transporter
CFC57_RS13570	COG3949	Membrane
CFC57_RS13575	COG0400	carboxylic ester hydrolase activity
CFC57_RS13580	COG0346	lactoylglutathione lyase activity
CFC57_RS13585	COG1846	Transcriptional regulator
CFC57_RS13595	COG2514	catechol 2,3-dioxygenase activity
CFC57_RS13610	COG0561	phosphatase activity
CFC57_RS13615	COG1131	(ABC) transporter
CFC57_RS13625	COG3764	Sortase (surface protein transpeptidase)
CFC57_RS13645	COG1760	l-serine dehydratase
CFC57_RS13650	COG1760	l-serine dehydratase
CFC57_RS13665	COG0697	spore germination
CFC57_RS13670	COG0657	acetylesterase activity
CFC57_RS13690	COG0028	Belongs to the TPP enzyme family
CFC57_RS13705	COG0583	DNA-binding transcription factor activity
CFC57_RS13715	COG3942	CHAP domain
CFC57_RS13725	COG3425	synthase
CFC57_RS13730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFC57_RS13755	COG2409	Drug exporters of the RND superfamily
CFC57_RS13800	COG0436	Aminotransferase
CFC57_RS13840	COG0456	acetyltransferase
CFC57_RS13905	COG0596	Alpha beta hydrolase
CFC57_RS13940	COG3001	Fructosamine kinase
CFC57_RS13945	COG0167	dihydroorotate dehydrogenase activity
CFC57_RS14000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFC57_RS14005	COG3527	Alpha-acetolactate decarboxylase
CFC57_RS14015	COG0531	amino acid
CFC57_RS14045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFC57_RS14065	COG1012	belongs to the aldehyde dehydrogenase family
CFC57_RS14075	COG1510	regulation of RNA biosynthetic process
CFC57_RS14080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFC57_RS14115	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFC57_RS14125	COG0386	Belongs to the glutathione peroxidase family
CFC57_RS14145	COG1136	(ABC) transporter
CFC57_RS14150	COG2205	protein histidine kinase activity
CFC57_RS14155	COG0745	RESPONSE REGULATOR receiver
CFC57_RS14165	COG1785	Belongs to the alkaline phosphatase family
CFC57_RS14175	COG1846	Transcriptional regulator
CFC57_RS14220	COG1438	arginine binding
CFC57_RS14245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFC57_RS14245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFC57_RS14245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFC57_RS14250	COG1482	cell wall glycoprotein biosynthetic process
CFC57_RS14260	COG1705	Flagellar rod assembly protein muramidase FlgJ
CFC57_RS14260	COG3942	CHAP domain
CFC57_RS14265	COG1535	isochorismatase
CFC57_RS14265	COG3433	isochorismatase activity
CFC57_RS14280	COG0438	transferase activity, transferring glycosyl groups
CFC57_RS14290	COG2826	transposase and inactivated derivatives, IS30 family
CFC57_RS14320	COG1674	ftsk spoiiie
CFC57_RS14330	COG0433	COG0433 Predicted ATPase
CFC57_RS14350	COG2946	Replication initiation factor
CFC57_RS14375	COG1073	alpha beta
CFC57_RS14395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFC57_RS14420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFC57_RS14585	COG0471	metal ion transport
CFC57_RS14590	COG2962	Rard protein
CFC57_RS14600	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CFC57_RS14620	COG1136	(ABC) transporter
CFC57_RS14625	COG0577	efflux transmembrane transporter activity
CFC57_RS14660	COG1278	Cold shock
CFC57_RS14680	COG1475	DNA binding