locus-tag	class	description
EKM74_RS00020	COG4548	von Willebrand factor, type A
EKM74_RS00025	COG0714	Associated with various cellular activities
EKM74_RS00070	COG0671	phosphoesterase, PA-phosphatase related
EKM74_RS00145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EKM74_RS00170	COG0531	amino acid
EKM74_RS00190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EKM74_RS00205	COG0116	Belongs to the methyltransferase superfamily
EKM74_RS00245	COG4499	WXG100 protein secretion system (Wss), protein YukC
EKM74_RS00245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKM74_RS00255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EKM74_RS00260	COG3935	DnaD domain protein
EKM74_RS00285	COG0438	transferase activity, transferring glycosyl groups
EKM74_RS00290	COG1694	Mazg nucleotide pyrophosphohydrolase
EKM74_RS00295	COG2738	Putative neutral zinc metallopeptidase
EKM74_RS00300	COG4347	Protein of unknown function (DUF1405)
EKM74_RS00340	COG0142	geranyltranstransferase activity
EKM74_RS00405	COG0492	ferredoxin-NADP+ reductase activity
EKM74_RS00420	COG0514	ATP-dependent DNA helicase (RecQ)
EKM74_RS00430	COG1141	Ferredoxin
EKM74_RS00475	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKM74_RS00475	COG1388	LysM domain
EKM74_RS00525	COG5280	Phage tail tape measure protein TP901
EKM74_RS00525	COG3953	SLT domain
EKM74_RS00795	COG0582	viral genome integration into host DNA
EKM74_RS00820	COG0745	RESPONSE REGULATOR receiver
EKM74_RS00825	COG1187	pseudouridine synthase activity
EKM74_RS00850	COG0735	belongs to the Fur family
EKM74_RS00855	COG0494	nUDIX hydrolase
EKM74_RS00860	COG0667	Aldo Keto reductase
EKM74_RS00870	COG4221	oxidoreductase activity
EKM74_RS00885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKM74_RS00895	COG0366	Alpha amylase catalytic
EKM74_RS00900	COG1609	Transcriptional regulator
EKM74_RS00925	COG2195	Cleaves the N-terminal amino acid of tripeptides
EKM74_RS00935	COG4129	membrane
EKM74_RS00945	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKM74_RS00950	COG0022	dehydrogenase e1 component
EKM74_RS00955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EKM74_RS00960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKM74_RS00965	COG0497	DNA recombination
EKM74_RS00995	COG1302	Protein conserved in bacteria
EKM74_RS01000	COG0439	Biotin carboxylase
EKM74_RS01005	COG0511	ligase activity, forming carbon-carbon bonds
EKM74_RS01015	COG0006	proline dipeptidase activity
EKM74_RS01030	COG0095	Lipoate-protein ligase
EKM74_RS01035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKM74_RS01080	COG4537	Required for transformation and DNA binding
EKM74_RS01085	COG1459	type II secretion system
EKM74_RS01090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EKM74_RS01095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKM74_RS01100	COG0011	TIGRFAM Protein of
EKM74_RS01105	COG1940	carbohydrate kinase activity
EKM74_RS01110	COG4483	Protein conserved in bacteria
EKM74_RS01120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKM74_RS01130	COG0768	penicillin binding
EKM74_RS01145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EKM74_RS01150	COG1121	(ABC) transporter
EKM74_RS01160	COG0513	Belongs to the DEAD box helicase family
EKM74_RS01170	COG2384	SAM-dependent methyltransferase
EKM74_RS01190	COG0517	IMP dehydrogenase activity
EKM74_RS01210	COG0295	cytidine deaminase activity
EKM74_RS01225	COG1702	phosphate starvation-inducible protein PhoH
EKM74_RS01250	COG1030	water channel activity
EKM74_RS01260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKM74_RS01265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EKM74_RS01295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EKM74_RS01315	COG1466	dna polymerase III delta subunit
EKM74_RS01335	COG2131	deaminase
EKM74_RS01340	COG2183	response to ionizing radiation
EKM74_RS01360	COG0799	negative regulation of ribosome biogenesis
EKM74_RS01365	COG1713	HD superfamily hydrolase involved in NAD metabolism
EKM74_RS01375	COG1534	Rna-binding protein
EKM74_RS01385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EKM74_RS01390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EKM74_RS01420	COG3177	Filamentation induced by cAMP protein fic
EKM74_RS01435	COG1914	H( )-stimulated, divalent metal cation uptake system
EKM74_RS01445	COG0439	Biotin carboxylase
EKM74_RS01450	COG0511	ligase activity, forming carbon-carbon bonds
EKM74_RS01455	COG1984	allophanate hydrolase subunit 2
EKM74_RS01460	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EKM74_RS01475	COG0826	peptidase U32
EKM74_RS01480	COG0826	peptidase U32
EKM74_RS01510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EKM74_RS01535	COG1104	cysteine desulfurase activity
EKM74_RS01545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKM74_RS01555	COG3237	CsbD-like
EKM74_RS01560	COG1959	2 iron, 2 sulfur cluster binding
EKM74_RS01565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EKM74_RS01570	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EKM74_RS01615	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EKM74_RS01615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EKM74_RS01620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKM74_RS01620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKM74_RS01625	COG1862	Preprotein translocase
EKM74_RS01665	COG2868	ribosomal protein
EKM74_RS01710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKM74_RS01755	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EKM74_RS01765	COG0285	dihydrofolate synthase activity
EKM74_RS01775	COG2818	Glycosylase
EKM74_RS01810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EKM74_RS01845	COG4112	unkown
EKM74_RS01870	COG0833	amino acid
EKM74_RS01885	COG1484	DNA-dependent DNA replication
EKM74_RS01915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKM74_RS01915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKM74_RS01925	COG5002	protein histidine kinase activity
EKM74_RS01930	COG0745	RESPONSE REGULATOR receiver
EKM74_RS01945	COG0372	Belongs to the citrate synthase family
EKM74_RS01955	COG1113	amino acid transport
EKM74_RS01980	COG0281	malic enzyme
EKM74_RS01990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EKM74_RS01995	COG4109	DRTGG domain
EKM74_RS02035	COG0827	DNA restriction-modification system
EKM74_RS02045	COG0730	response to heat
EKM74_RS02055	COG1104	cysteine desulfurase activity
EKM74_RS02070	COG1956	GAF domain-containing protein
EKM74_RS02095	COG0584	glycerophosphoryl diester phosphodiesterase
EKM74_RS02100	COG1764	response to oxidative stress
EKM74_RS02105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EKM74_RS02110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EKM74_RS02125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKM74_RS02125	COG1263	PTS System
EKM74_RS02130	COG0204	Acyl-transferase
EKM74_RS02135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKM74_RS02170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EKM74_RS02175	COG0454	-acetyltransferase
EKM74_RS02195	COG1605	Chorismate mutase
EKM74_RS02195	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EKM74_RS02220	COG1674	ftsk spoiiie
EKM74_RS02225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKM74_RS02235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKM74_RS02240	COG1363	Peptidase, m42
EKM74_RS02250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKM74_RS02260	COG0510	thiamine kinase activity
EKM74_RS02280	COG1187	pseudouridine synthase activity
EKM74_RS02285	COG2244	polysaccharide biosynthetic process
EKM74_RS02290	COG2081	HI0933 family
EKM74_RS02310	COG2814	Major facilitator Superfamily
EKM74_RS02315	COG1242	4 iron, 4 sulfur cluster binding
EKM74_RS02320	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EKM74_RS02335	COG2267	carboxylic ester hydrolase activity
EKM74_RS02365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKM74_RS02365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKM74_RS02385	COG3266	domain, Protein
EKM74_RS02385	COG5632	N-Acetylmuramoyl-L-alanine amidase
EKM74_RS02385	COG4193	domain, Protein
EKM74_RS02425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EKM74_RS02450	COG0656	L-ascorbic acid biosynthetic process
EKM74_RS02470	COG1506	peptidase
EKM74_RS02475	COG2816	NAD+ diphosphatase activity
EKM74_RS02715	COG1388	LysM domain
EKM74_RS02715	COG5632	N-Acetylmuramoyl-L-alanine amidase
EKM74_RS03070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EKM74_RS03100	COG1131	(ABC) transporter
EKM74_RS03105	COG0537	adenosine 5'-monophosphoramidase activity
EKM74_RS03135	COG0420	3'-5' exonuclease activity
EKM74_RS03165	COG2197	response regulator
EKM74_RS03170	COG2203	Gaf domain
EKM74_RS03170	COG4585	Histidine kinase
EKM74_RS03175	COG0564	pseudouridine synthase activity
EKM74_RS03205	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EKM74_RS03210	COG1126	abc transporter atp-binding protein
EKM74_RS03215	COG0765	amino acid transport
EKM74_RS03385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EKM74_RS03390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EKM74_RS03400	COG4129	membrane
EKM74_RS03425	COG1988	membrane-bound metal-dependent
EKM74_RS03440	COG1388	LysM domain
EKM74_RS03440	COG1134	teichoic acid transport
EKM74_RS03470	COG0535	radical SAM domain protein
EKM74_RS03475	COG1607	acyl-coa hydrolase
EKM74_RS03480	COG2309	aminopeptidase activity
EKM74_RS03500	COG1295	ribonuclease BN
EKM74_RS03625	COG4851	CamS sex pheromone cAM373 precursor
EKM74_RS03645	COG4496	protein, YerC YecD
EKM74_RS03690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EKM74_RS03700	COG0077	Prephenate dehydratase
EKM74_RS03710	COG0471	metal ion transport
EKM74_RS03720	COG1335	isochorismatase
EKM74_RS03735	COG1012	belongs to the aldehyde dehydrogenase family
EKM74_RS03790	COG1131	(ABC) transporter
EKM74_RS03805	COG1725	Transcriptional regulator
EKM74_RS03905	COG5632	N-Acetylmuramoyl-L-alanine amidase
EKM74_RS03905	COG1388	LysM domain
EKM74_RS03940	COG0456	acetyltransferase
EKM74_RS03980	COG0739	heme binding
EKM74_RS04030	COG0740	serine-type endopeptidase activity
EKM74_RS04200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKM74_RS04255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EKM74_RS04285	COG3728	DNA packaging
EKM74_RS04285	COG5484	DNA packaging
EKM74_RS04365	COG0582	viral genome integration into host DNA
EKM74_RS04440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKM74_RS04445	COG1621	beta-fructofuranosidase activity
EKM74_RS04450	COG1609	Transcriptional regulator
EKM74_RS04455	COG0004	ammonium transporteR
EKM74_RS04460	COG0425	Belongs to the sulfur carrier protein TusA family
EKM74_RS04465	COG2391	methyltransferase activity
EKM74_RS04475	COG0488	(ABC) transporter
EKM74_RS04485	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EKM74_RS04495	COG0456	acetyltransferase
EKM74_RS04500	COG1214	PFAM Peptidase M22, glycoprotease
EKM74_RS04505	COG0802	atpase or kinase
EKM74_RS04520	COG0028	Belongs to the TPP enzyme family
EKM74_RS04595	COG2183	response to ionizing radiation
EKM74_RS04600	COG1191	sigma factor activity
EKM74_RS04610	COG1366	Belongs to the anti-sigma-factor antagonist family
EKM74_RS04615	COG2208	phosphoserine phosphatase activity
EKM74_RS04650	COG3428	Bacterial PH domain
EKM74_RS04680	COG2205	protein histidine kinase activity
EKM74_RS04685	COG0745	RESPONSE REGULATOR receiver
EKM74_RS04705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EKM74_RS04730	COG1937	Protein conserved in bacteria
EKM74_RS04740	COG1418	mRNA catabolic process
EKM74_RS04795	COG0629	single-stranded DNA binding
EKM74_RS04870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EKM74_RS04895	COG0009	L-threonylcarbamoyladenylate synthase
EKM74_RS04900	COG2890	protein-(glutamine-N5) methyltransferase activity
EKM74_RS04925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EKM74_RS04965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKM74_RS05015	COG0813	purine-nucleoside phosphorylase activity
EKM74_RS05020	COG0783	Belongs to the Dps family
EKM74_RS05040	COG1482	cell wall glycoprotein biosynthetic process
EKM74_RS05045	COG0702	epimerase
EKM74_RS05050	COG0640	Transcriptional regulator
EKM74_RS05085	COG0561	phosphatase activity
EKM74_RS05090	COG1119	ATPase activity
EKM74_RS05105	COG3711	transcriptional antiterminator
EKM74_RS05135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKM74_RS05195	COG0489	protein tyrosine kinase activity
EKM74_RS05200	COG2814	Major facilitator Superfamily
EKM74_RS05215	COG1272	protein, Hemolysin III
EKM74_RS05225	COG1988	membrane-bound metal-dependent
EKM74_RS05235	COG3314	Sporulation integral membrane protein YlbJ
EKM74_RS05240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKM74_RS05245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKM74_RS05250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EKM74_RS05260	COG3457	Alanine racemase
EKM74_RS05265	COG4264	IucA IucC family
EKM74_RS05270	COG2814	Major facilitator Superfamily
EKM74_RS05295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EKM74_RS05305	COG2130	NADP-dependent
EKM74_RS05370	COG0656	L-ascorbic acid biosynthetic process
EKM74_RS05375	COG0789	Transcriptional regulator
EKM74_RS05385	COG5492	domain, Protein
EKM74_RS05405	COG3527	Alpha-acetolactate decarboxylase
EKM74_RS05410	COG0028	Belongs to the TPP enzyme family
EKM74_RS05530	COG0201	protein transport
EKM74_RS05645	COG2252	PERMEase
EKM74_RS05695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKM74_RS05765	COG1763	Mo-molybdopterin cofactor biosynthetic process
EKM74_RS05785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EKM74_RS05790	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EKM74_RS05795	COG4149	molybdate abc transporter
EKM74_RS05800	COG0725	ABC transporter, periplasmic molybdate-binding protein
EKM74_RS05815	COG1268	BioY protein
EKM74_RS05830	COG1960	acyl-CoA dehydrogenase activity
EKM74_RS05835	COG4413	Urea transporter
EKM74_RS05900	COG3942	CHAP domain
EKM74_RS05910	COG1757	Na H antiporter
EKM74_RS05925	COG3942	CHAP domain
EKM74_RS06000	COG1113	amino acid transport
EKM74_RS06020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EKM74_RS06025	COG0385	Bile acid
EKM74_RS06035	COG1263	PTS System
EKM74_RS06035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKM74_RS06040	COG1737	Transcriptional regulator
EKM74_RS06060	COG1028	Short-chain dehydrogenase reductase Sdr
EKM74_RS06065	COG1473	amidohydrolase
EKM74_RS06120	COG2258	MOSC domain
EKM74_RS06140	COG1668	transmembrane transport
EKM74_RS06145	COG4152	abc transporter atp-binding protein
EKM74_RS06150	COG3152	Membrane
EKM74_RS06170	COG0786	glutamate:sodium symporter activity
EKM74_RS06180	COG0598	Magnesium transport protein CorA
EKM74_RS06195	COG0657	acetylesterase activity
EKM74_RS06205	COG2814	Major facilitator Superfamily
EKM74_RS06210	COG1566	PFAM secretion protein HlyD family protein
EKM74_RS06220	COG2814	Major facilitator Superfamily
EKM74_RS06285	COG1620	l-lactate permease
EKM74_RS06305	COG0604	alcohol dehydrogenase
EKM74_RS06335	COG1511	domain protein
EKM74_RS06350	COG1263	PTS System
EKM74_RS06350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKM74_RS06370	COG3871	stress protein (general stress protein 26)
EKM74_RS06410	COG0789	Transcriptional regulator
EKM74_RS06430	COG2181	nitrate reductase activity
EKM74_RS06440	COG1140	nitrate reductase beta subunit
EKM74_RS06445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKM74_RS06455	COG2146	nitrite reductase [NAD(P)H] activity
EKM74_RS06460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKM74_RS06470	COG0454	-acetyltransferase
EKM74_RS06475	COG2116	formate transmembrane transporter activity
EKM74_RS06490	COG3443	Belongs to the bacterial solute-binding protein 9 family
EKM74_RS06490	COG0803	Belongs to the bacterial solute-binding protein 9 family
EKM74_RS06530	COG1126	abc transporter atp-binding protein
EKM74_RS06535	COG0765	amino acid transport
EKM74_RS06540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EKM74_RS06545	COG2814	Major facilitator Superfamily
EKM74_RS06565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKM74_RS06615	COG0156	8-amino-7-oxononanoate synthase activity
EKM74_RS06625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EKM74_RS06630	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EKM74_RS06645	COG1132	(ABC) transporter
EKM74_RS06650	COG1132	(ABC) transporter
EKM74_RS06650	COG2375	cellular response to nickel ion
EKM74_RS06670	COG1929	Belongs to the glycerate kinase type-1 family
EKM74_RS06680	COG2814	Major facilitator Superfamily
EKM74_RS06700	COG1113	amino acid transport
EKM74_RS06715	COG0531	amino acid
EKM74_RS06740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKM74_RS06750	COG1174	glycine betaine transport
EKM74_RS06760	COG1174	glycine betaine transport
EKM74_RS06780	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EKM74_RS06790	COG0531	amino acid
EKM74_RS06795	COG2272	Belongs to the type-B carboxylesterase lipase family
EKM74_RS06800	COG2814	Major facilitator Superfamily
EKM74_RS06805	COG0390	transport system, permease component
EKM74_RS06810	COG4619	ABC transporter
EKM74_RS06815	COG1363	Peptidase, m42
EKM74_RS06835	COG4808	Protein conserved in bacteria
EKM74_RS06840	COG0069	glutamate synthase activity
EKM74_RS06895	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EKM74_RS06900	COG1028	Short-chain dehydrogenase reductase Sdr
EKM74_RS06905	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EKM74_RS06910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKM74_RS07000	COG0745	RESPONSE REGULATOR receiver
EKM74_RS07060	COG2003	Belongs to the UPF0758 family
EKM74_RS07100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKM74_RS07120	COG0730	response to heat
EKM74_RS07125	COG1937	Protein conserved in bacteria
EKM74_RS07130	COG2210	Belongs to the sulfur carrier protein TusA family
EKM74_RS07135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKM74_RS07145	COG1940	carbohydrate kinase activity
EKM74_RS07145	COG1846	Transcriptional regulator
EKM74_RS07170	COG2030	dehydratase
EKM74_RS07175	COG0584	glycerophosphoryl diester phosphodiesterase
EKM74_RS07185	COG3425	synthase
EKM74_RS07235	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EKM74_RS07240	COG0732	type I restriction modification DNA specificity domain
EKM74_RS07240	COG0732	type I restriction modification DNA specificity domain
EKM74_RS07245	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EKM74_RS07305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKM74_RS07310	COG1028	Short-chain dehydrogenase reductase Sdr
EKM74_RS07365	COG1438	arginine binding
EKM74_RS07370	COG2235	arginine
EKM74_RS07380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKM74_RS07385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKM74_RS07390	COG0549	Belongs to the carbamate kinase family
EKM74_RS07395	COG2801	Transposase and inactivated derivatives
EKM74_RS07455	COG0737	Belongs to the 5'-nucleotidase family
EKM74_RS07460	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EKM74_RS07470	COG4863	YycH protein
EKM74_RS07505	COG0305	Participates in initiation and elongation during chromosome replication
EKM74_RS07515	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EKM74_RS07525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKM74_RS07555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EKM74_RS07575	COG2501	S4 domain
EKM74_RS07615	COG1475	DNA binding
EKM74_RS07640	COG1278	Cold shock
EKM74_RS07650	COG0577	efflux transmembrane transporter activity
EKM74_RS07655	COG1136	(ABC) transporter
EKM74_RS07670	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EKM74_RS07680	COG2962	Rard protein
EKM74_RS07685	COG0471	metal ion transport
EKM74_RS07770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKM74_RS07865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKM74_RS07885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKM74_RS07905	COG1073	alpha beta
EKM74_RS07920	COG0438	transferase activity, transferring glycosyl groups
EKM74_RS07935	COG3433	isochorismatase activity
EKM74_RS07935	COG1535	isochorismatase
EKM74_RS07940	COG1705	Flagellar rod assembly protein muramidase FlgJ
EKM74_RS07940	COG3942	CHAP domain
EKM74_RS07950	COG1482	cell wall glycoprotein biosynthetic process
EKM74_RS07955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKM74_RS07955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKM74_RS07955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKM74_RS07960	COG3711	transcriptional antiterminator
EKM74_RS07960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKM74_RS07980	COG1438	arginine binding
EKM74_RS08025	COG1846	Transcriptional regulator
EKM74_RS08035	COG1785	Belongs to the alkaline phosphatase family
EKM74_RS08045	COG0745	RESPONSE REGULATOR receiver
EKM74_RS08050	COG2205	protein histidine kinase activity
EKM74_RS08055	COG1136	(ABC) transporter
EKM74_RS08080	COG0386	Belongs to the glutathione peroxidase family
EKM74_RS08090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EKM74_RS08105	COG2851	Citrate transporter
EKM74_RS08130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EKM74_RS08135	COG1510	regulation of RNA biosynthetic process
EKM74_RS08145	COG1012	belongs to the aldehyde dehydrogenase family
EKM74_RS08165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EKM74_RS08195	COG0531	amino acid
EKM74_RS08210	COG3527	Alpha-acetolactate decarboxylase
EKM74_RS08215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKM74_RS08280	COG0167	dihydroorotate dehydrogenase activity
EKM74_RS08285	COG3001	Fructosamine kinase
EKM74_RS08405	COG2755	lipolytic protein G-D-S-L family
EKM74_RS08405	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EKM74_RS08410	COG3942	CHAP domain
EKM74_RS08440	COG0436	Aminotransferase
EKM74_RS08485	COG2409	Drug exporters of the RND superfamily
EKM74_RS08515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKM74_RS08520	COG3425	synthase
EKM74_RS08530	COG3942	CHAP domain
EKM74_RS08540	COG0583	DNA-binding transcription factor activity
EKM74_RS08555	COG0028	Belongs to the TPP enzyme family
EKM74_RS08575	COG0657	acetylesterase activity
EKM74_RS08580	COG0697	spore germination
EKM74_RS08595	COG1760	l-serine dehydratase
EKM74_RS08600	COG1760	l-serine dehydratase
EKM74_RS08620	COG3764	Sortase (surface protein transpeptidase)
EKM74_RS08630	COG1131	(ABC) transporter
EKM74_RS08635	COG0561	phosphatase activity
EKM74_RS08650	COG2514	catechol 2,3-dioxygenase activity
EKM74_RS08660	COG1846	Transcriptional regulator
EKM74_RS08665	COG0346	lactoylglutathione lyase activity
EKM74_RS08670	COG0400	carboxylic ester hydrolase activity
EKM74_RS08690	COG1131	(ABC) transporter
EKM74_RS08710	COG0586	Pfam SNARE associated Golgi protein
EKM74_RS08715	COG2271	Major facilitator Superfamily
EKM74_RS08725	COG4876	unkown
EKM74_RS08730	COG2357	RelA SpoT domain protein
EKM74_RS08735	COG0789	Transcriptional regulator
EKM74_RS08740	COG1802	Transcriptional regulator
EKM74_RS08745	COG1070	Carbohydrate kinase
EKM74_RS08795	COG1846	Transcriptional regulator
EKM74_RS08840	COG0494	nUDIX hydrolase
EKM74_RS08940	COG0730	response to heat
EKM74_RS08945	COG1937	Protein conserved in bacteria
EKM74_RS08950	COG2210	Belongs to the sulfur carrier protein TusA family
EKM74_RS08955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKM74_RS09005	COG0823	Involved in the tonB-independent uptake of proteins
EKM74_RS09040	COG1473	amidohydrolase
EKM74_RS09050	COG1283	sodium-dependent phosphate transmembrane transporter activity
EKM74_RS09055	COG4716	Myosin-crossreactive antigen
EKM74_RS09090	COG1620	l-lactate permease
EKM74_RS09110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKM74_RS09115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKM74_RS09120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKM74_RS09130	COG2423	ornithine cyclodeaminase activity
EKM74_RS09135	COG4264	IucA IucC family
EKM74_RS09140	COG2814	Major facilitator Superfamily
EKM74_RS09145	COG4264	IucA IucC family
EKM74_RS09150	COG4264	IucA IucC family
EKM74_RS09160	COG0019	diaminopimelate decarboxylase activity
EKM74_RS09165	COG1475	DNA binding
EKM74_RS09190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKM74_RS09195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EKM74_RS09200	COG0438	transferase activity, transferring glycosyl groups
EKM74_RS09235	COG0813	purine-nucleoside phosphorylase activity
EKM74_RS09240	COG2814	Major facilitator Superfamily
EKM74_RS09260	COG3639	organic phosphonate transmembrane transporter activity
EKM74_RS09280	COG0737	Belongs to the 5'-nucleotidase family
EKM74_RS09295	COG1454	alcohol dehydrogenase
EKM74_RS09295	COG1012	belongs to the aldehyde dehydrogenase family
EKM74_RS09320	COG1086	Polysaccharide biosynthesis protein
EKM74_RS09330	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EKM74_RS09360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EKM74_RS09370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EKM74_RS09375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EKM74_RS09385	COG2832	Protein of unknown function (DUF454)
EKM74_RS09420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EKM74_RS09425	COG1960	acyl-CoA dehydrogenase activity
EKM74_RS09430	COG5609	conserved protein (DUF2294)
EKM74_RS09480	COG1114	Component of the transport system for branched-chain amino acids
EKM74_RS09485	COG1335	isochorismatase
EKM74_RS09490	COG3961	Belongs to the TPP enzyme family
EKM74_RS09520	COG1737	Transcriptional regulator
EKM74_RS09545	COG1136	(ABC) transporter
EKM74_RS09550	COG1136	(ABC) transporter
EKM74_RS09550	COG0577	efflux transmembrane transporter activity
EKM74_RS09575	COG1131	(ABC) transporter
EKM74_RS09590	COG0601	transmembrane transport
EKM74_RS09595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKM74_RS09605	COG0405	Gamma-glutamyltransferase
EKM74_RS09625	COG3842	ATPase activity
EKM74_RS09635	COG1175	transmembrane transport
EKM74_RS09640	COG3833	ABC-type maltose transport systems, permease component
EKM74_RS09645	COG0673	inositol 2-dehydrogenase activity
EKM74_RS09650	COG0673	inositol 2-dehydrogenase activity
EKM74_RS09660	COG1755	Isoprenylcysteine carboxyl methyltransferase
EKM74_RS09715	COG0183	Belongs to the thiolase family
EKM74_RS09725	COG1960	acyl-CoA dehydrogenase activity
EKM74_RS09730	COG0318	PFAM AMP-dependent synthetase and ligase
EKM74_RS09745	COG0747	negative chemotaxis
EKM74_RS09750	COG3189	MarR family transcriptional regulator
EKM74_RS09785	COG1263	PTS System
EKM74_RS09785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKM74_RS09785	COG2190	(PTS) system
EKM74_RS09790	COG1957	nucleoside hydrolase
EKM74_RS09810	COG3414	Phosphotransferase system galactitol-specific IIB component
EKM74_RS09815	COG3775	system Galactitol-specific IIC component
EKM74_RS09820	COG1063	alcohol dehydrogenase
EKM74_RS09830	COG1063	alcohol dehydrogenase
EKM74_RS09840	COG1063	alcohol dehydrogenase
EKM74_RS09845	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKM74_RS09850	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKM74_RS09860	COG1063	alcohol dehydrogenase
EKM74_RS09865	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKM74_RS09900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKM74_RS09910	COG1263	PTS System
EKM74_RS09910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKM74_RS09910	COG2190	(PTS) system
EKM74_RS09915	COG2723	6-phospho-beta-galactosidase activity
EKM74_RS09925	COG2226	methyltransferase
EKM74_RS09980	COG1131	(ABC) transporter
EKM74_RS10000	COG1388	LysM domain
EKM74_RS10000	COG3942	CHAP domain
EKM74_RS10120	COG1114	Component of the transport system for branched-chain amino acids
EKM74_RS10130	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EKM74_RS10140	COG0577	efflux transmembrane transporter activity
EKM74_RS10170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKM74_RS10175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKM74_RS10200	COG3314	Sporulation integral membrane protein YlbJ
EKM74_RS10225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKM74_RS10255	COG3037	sugar-specific permease SgaT UlaA
EKM74_RS10265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKM74_RS10270	COG3711	transcriptional antiterminator
EKM74_RS10295	COG2271	Major facilitator Superfamily
EKM74_RS10300	COG0346	lactoylglutathione lyase activity
EKM74_RS10305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKM74_RS10310	COG0431	NADPH-dependent FMN reductase
EKM74_RS10325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKM74_RS10330	COG2822	iron ion transport
EKM74_RS10340	COG0672	)-iron permease
EKM74_RS10345	COG0805	protein transport
EKM74_RS10350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKM74_RS10360	COG1476	TRANSCRIPTIONal
EKM74_RS10370	COG1131	(ABC) transporter
EKM74_RS10400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EKM74_RS10400	COG0646	methionine synthase
EKM74_RS10405	COG0626	cystathionine gamma-synthase activity
EKM74_RS10410	COG0626	cystathionine gamma-synthase activity
EKM74_RS10420	COG1475	DNA binding
EKM74_RS10425	COG0668	transmembrane transport
EKM74_RS10430	COG4481	Protein conserved in bacteria
EKM74_RS10435	COG0012	GTP binding
EKM74_RS10540	COG1823	symporter activity
EKM74_RS10580	COG2233	PERMEase
EKM74_RS10595	COG0582	viral genome integration into host DNA
EKM74_RS10655	COG0791	NLP P60 protein
EKM74_RS10655	COG0741	lytic transglycosylase activity
EKM74_RS10700	COG2946	Replication initiation factor
EKM74_RS10705	COG1674	ftsk spoiiie
EKM74_RS10745	COG3328	transposase activity
EKM74_RS10780	COG3759	membrane
EKM74_RS10965	COG0523	cobalamin synthesis protein
EKM74_RS10990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EKM74_RS11000	COG5609	conserved protein (DUF2294)
EKM74_RS11015	COG1647	Serine aminopeptidase, S33
EKM74_RS11020	COG0733	neurotransmitter:sodium symporter activity
EKM74_RS11025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EKM74_RS11030	COG0626	cystathionine gamma-synthase activity
EKM74_RS11040	COG2011	ABC-type metal ion transport system permease component
EKM74_RS11045	COG1464	Belongs to the NlpA lipoprotein family
EKM74_RS11080	COG0583	DNA-binding transcription factor activity
EKM74_RS11085	COG0070	glutamate synthase
EKM74_RS11085	COG0067	glutamate synthase
EKM74_RS11085	COG0069	glutamate synthase activity
EKM74_RS11090	COG0493	'glutamate synthase
EKM74_RS11100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKM74_RS11100	COG1263	PTS System
EKM74_RS11105	COG0366	Alpha amylase catalytic
EKM74_RS11110	COG2188	Transcriptional regulator
EKM74_RS11130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKM74_RS11175	COG1982	Orn Lys Arg decarboxylase major
EKM74_RS11185	COG3870	Protein conserved in bacteria
EKM74_RS11190	COG0470	DNA polymerase III
EKM74_RS11195	COG1774	PSP1 C-terminal conserved region
EKM74_RS11205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EKM74_RS11215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EKM74_RS11225	COG0084	hydrolase, TatD family'
EKM74_RS11230	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EKM74_RS11240	COG4466	Protein conserved in bacteria
EKM74_RS11250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKM74_RS11255	COG0251	oxidation-reduction process
EKM74_RS11300	COG2244	polysaccharide biosynthetic process
EKM74_RS11305	COG3956	TIGRFAM MazG family protein
EKM74_RS11310	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EKM74_RS11320	COG1098	S1 RNA binding domain
EKM74_RS11335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKM74_RS11360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EKM74_RS11440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKM74_RS11455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKM74_RS11465	COG3880	PFAM UvrB UvrC protein
EKM74_RS11480	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EKM74_RS11485	COG4956	integral membrane protein (PIN domain superfamily)
EKM74_RS11510	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EKM74_RS11570	COG2813	Specifically methylates the guanine in position
EKM74_RS11610	COG1473	amidohydrolase
EKM74_RS11645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EKM74_RS11650	COG1428	Deoxynucleoside kinase
EKM74_RS11655	COG1428	Deoxynucleoside kinase
EKM74_RS11665	COG0561	phosphatase activity
EKM74_RS11710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EKM74_RS11725	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EKM74_RS11825	COG0095	Lipoate-protein ligase
EKM74_RS11830	COG0083	homoserine kinase activity
EKM74_RS11850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKM74_RS11885	COG0667	Aldo Keto reductase
EKM74_RS11895	COG0655	NAD(P)H dehydrogenase (quinone) activity
EKM74_RS11905	COG1078	dGTPase activity
EKM74_RS11950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKM74_RS11955	COG4139	cobalamin transport
EKM74_RS12005	COG4974	Belongs to the 'phage' integrase family
EKM74_RS12060	COG0803	Belongs to the bacterial solute-binding protein 9 family
EKM74_RS12065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EKM74_RS12070	COG1121	(ABC) transporter
EKM74_RS12075	COG1321	iron dependent repressor
EKM74_RS12085	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EKM74_RS12095	COG1682	transport, permease protein
EKM74_RS12100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKM74_RS12110	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EKM74_RS12115	COG1686	Belongs to the peptidase S11 family
EKM74_RS12120	COG1132	(ABC) transporter
EKM74_RS12125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKM74_RS12135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKM74_RS12140	COG1120	ATPase activity
EKM74_RS12145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKM74_RS12150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKM74_RS12155	COG2376	Dihydroxyacetone kinase
EKM74_RS12165	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EKM74_RS12175	COG3949	Membrane
EKM74_RS12200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKM74_RS12215	COG1136	(ABC) transporter
EKM74_RS12220	COG0577	efflux transmembrane transporter activity
EKM74_RS12225	COG1392	Phosphate transport regulator
EKM74_RS12230	COG0306	phosphate transporter
EKM74_RS12235	COG3942	CHAP domain
EKM74_RS12235	COG1388	LysM domain
EKM74_RS12245	COG1917	Cupin 2, conserved barrel domain protein
EKM74_RS12245	COG4977	sequence-specific DNA binding
EKM74_RS12275	COG0583	DNA-binding transcription factor activity
EKM74_RS12280	COG2814	Major facilitator Superfamily
EKM74_RS12285	COG2839	Protein conserved in bacteria
EKM74_RS12315	COG1611	Belongs to the LOG family
EKM74_RS12335	COG4988	ABC transporter
EKM74_RS12340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EKM74_RS12350	COG0523	cobalamin synthesis protein
EKM74_RS12355	COG4989	oxidoreductase activity
EKM74_RS12365	COG0471	metal ion transport
EKM74_RS12370	COG0415	Belongs to the DNA photolyase family
EKM74_RS12410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EKM74_RS12415	COG1349	DNA-binding transcription factor activity
EKM74_RS12420	COG1105	Belongs to the carbohydrate kinase PfkB family
EKM74_RS12425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKM74_RS12425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKM74_RS12425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKM74_RS12430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EKM74_RS12435	COG1253	flavin adenine dinucleotide binding
EKM74_RS12440	COG0656	L-ascorbic acid biosynthetic process
EKM74_RS12445	COG0463	Glycosyl transferase, family 2
EKM74_RS12480	COG0720	synthase
EKM74_RS12490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EKM74_RS12490	COG0512	Glutamine amidotransferase of anthranilate synthase
EKM74_RS12495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKM74_RS12525	COG0488	(ABC) transporter
EKM74_RS12530	COG0514	ATP-dependent DNA helicase (RecQ)
EKM74_RS12535	COG0517	IMP dehydrogenase activity
EKM74_RS12535	COG1125	glycine betaine transport
EKM74_RS12540	COG1174	glycine betaine transport
EKM74_RS12575	COG3104	oligopeptide transport
EKM74_RS12605	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKM74_RS12610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKM74_RS12620	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKM74_RS12625	COG4605	iron ion homeostasis
EKM74_RS12630	COG4604	ABC transporter, ATP-binding protein
EKM74_RS12635	COG4607	ABC-type enterochelin transport system periplasmic component
EKM74_RS12690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKM74_RS12695	COG1739	Uncharacterized protein family UPF0029
EKM74_RS12705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EKM74_RS12710	COG1040	competence protein
EKM74_RS12740	COG3942	CHAP domain
EKM74_RS12740	COG1388	LysM domain
EKM74_RS12800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EKM74_RS12870	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EKM74_RS12875	COG1647	Serine aminopeptidase, S33
EKM74_RS12880	COG0557	exoribonuclease II activity
EKM74_RS12985	COG3728	DNA packaging
EKM74_RS12985	COG5484	DNA packaging
EKM74_RS13005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKM74_RS13010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EKM74_RS13080	COG1278	Cold shock
EKM74_RS13120	COG0406	alpha-ribazole phosphatase activity
EKM74_RS13125	COG1279	arginine transmembrane transporter activity
EKM74_RS13150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKM74_RS13155	COG1393	Belongs to the ArsC family
EKM74_RS13170	COG3878	Protein conserved in bacteria
EKM74_RS13180	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EKM74_RS13195	COG2011	ABC-type metal ion transport system permease component
EKM74_RS13200	COG1464	Belongs to the NlpA lipoprotein family
EKM74_RS13215	COG0396	ATPase activity
EKM74_RS13220	COG0719	Fe-S assembly protein
EKM74_RS13230	COG0822	iron-sulfur transferase activity
EKM74_RS13255	COG1253	flavin adenine dinucleotide binding
EKM74_RS13270	COG1801	Protein of unknown function DUF72
EKM74_RS13275	COG0730	response to heat
EKM74_RS13290	COG4470	Protein conserved in bacteria
EKM74_RS13310	COG2445	Protein of unknown function DUF86
EKM74_RS13340	COG1696	Membrane protein involved in D-alanine export
EKM74_RS13350	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EKM74_RS13355	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EKM74_RS13360	COG4837	Protein of unknown function (DUF1462)
EKM74_RS13365	COG1252	NADH dehydrogenase
EKM74_RS13375	COG0316	Belongs to the HesB IscA family
EKM74_RS13385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKM74_RS13390	COG2056	Na+-H+ antiporter family
EKM74_RS13395	COG2050	protein possibly involved in aromatic compounds catabolism
EKM74_RS13450	COG1098	S1 RNA binding domain
EKM74_RS13455	COG1902	pentaerythritol trinitrate reductase activity
EKM74_RS13470	COG0584	glycerophosphoryl diester phosphodiesterase
EKM74_RS13490	COG0398	Pfam SNARE associated Golgi protein
EKM74_RS13530	COG0561	phosphatase activity
EKM74_RS13555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKM74_RS13580	COG1881	PFAM PEBP family protein
EKM74_RS13610	COG0601	transmembrane transport
EKM74_RS13615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKM74_RS13620	COG0444	Belongs to the ABC transporter superfamily
EKM74_RS13625	COG4608	Belongs to the ABC transporter superfamily
EKM74_RS13630	COG4166	transmembrane transport
EKM74_RS13635	COG0747	negative chemotaxis
EKM74_RS13640	COG0444	Belongs to the ABC transporter superfamily
EKM74_RS13645	COG4608	Belongs to the ABC transporter superfamily
EKM74_RS13660	COG0601	transmembrane transport
EKM74_RS13665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKM74_RS13690	COG1164	Oligoendopeptidase f
EKM74_RS13700	COG2346	COG2346, Truncated hemoglobins
EKM74_RS13715	COG2357	RelA SpoT domain protein
EKM74_RS13725	COG0564	pseudouridine synthase activity
EKM74_RS13730	COG2239	Acts as a magnesium transporter
EKM74_RS13735	COG0475	glutathione-regulated potassium exporter activity
EKM74_RS13735	COG0569	domain protein
EKM74_RS13745	COG0628	permease
EKM74_RS13750	COG1115	amino acid carrier protein
EKM74_RS13790	COG0861	Integral membrane protein TerC family
EKM74_RS13800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EKM74_RS13805	COG0737	Belongs to the 5'-nucleotidase family
EKM74_RS13820	COG4903	ComK protein
EKM74_RS13835	COG4873	Protein conserved in bacteria
EKM74_RS13895	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EKM74_RS13905	COG2314	TM2 domain
EKM74_RS13910	COG0456	acetyltransferase
EKM74_RS13915	COG1575	Belongs to the MenA family. Type 1 subfamily
EKM74_RS13925	COG1169	isochorismate synthase
EKM74_RS13935	COG2267	carboxylic ester hydrolase activity
EKM74_RS13960	COG0436	Aminotransferase
EKM74_RS13965	COG3594	Acyltransferase
EKM74_RS13995	COG1316	TRANSCRIPTIONal
EKM74_RS14040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EKM74_RS14055	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKM74_RS14095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKM74_RS14100	COG4172	Belongs to the ABC transporter superfamily
EKM74_RS14105	COG4721	ABC-type cobalt transport system, permease component
EKM74_RS14130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EKM74_RS14150	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EKM74_RS14155	COG1271	oxidase subunit
EKM74_RS14160	COG1294	oxidase, subunit
EKM74_RS14165	COG0569	domain protein
EKM74_RS14230	COG1176	ABC-type spermidine putrescine transport system, permease component I
EKM74_RS14235	COG1177	transmembrane transport
EKM74_RS14240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EKM74_RS14270	COG0483	inositol monophosphate 1-phosphatase activity
EKM74_RS14280	COG1217	gtp-binding protein TYPA
EKM74_RS14290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EKM74_RS14300	COG0772	Belongs to the SEDS family
EKM74_RS14335	COG3679	Belongs to the UPF0342 family
EKM74_RS14355	COG0742	ribosomal rna small subunit methyltransferase
EKM74_RS14400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKM74_RS14410	COG3617	BRO family, N-terminal domain
EKM74_RS14475	COG1484	DNA-dependent DNA replication
EKM74_RS14710	COG5632	N-Acetylmuramoyl-L-alanine amidase
EKM74_RS14710	COG1388	LysM domain
EKM74_RS14750	COG4509	Sortase family
EKM74_RS14765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKM74_RS14810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EKM74_RS14810	COG1796	DNA polymerase
EKM74_RS14835	COG2009	succinate dehydrogenase
EKM74_RS14840	COG1053	succinate dehydrogenase
EKM74_RS14845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EKM74_RS14980	COG1288	antiporter activity
EKM74_RS15015	COG1011	Hydrolase
EKM74_RS15040	COG4839	cell division protein FtsL
EKM74_RS15045	COG0768	penicillin binding
EKM74_RS15060	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EKM74_RS15065	COG0849	cell division
EKM74_RS15080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EKM74_RS15090	COG0762	integral membrane protein
EKM74_RS15095	COG2302	S4 RNA-binding domain
EKM74_RS15100	COG3599	regulation of cell shape
EKM74_RS15110	COG2514	catechol 2,3-dioxygenase activity
EKM74_RS15130	COG0564	pseudouridine synthase activity
EKM74_RS15140	COG2233	PERMEase
EKM74_RS15185	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EKM74_RS15200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKM74_RS15205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKM74_RS15215	COG2314	TM2 domain
EKM74_RS15230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKM74_RS15230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKM74_RS15240	COG0631	protein serine/threonine phosphatase activity
EKM74_RS15255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EKM74_RS15270	COG1302	Protein conserved in bacteria
EKM74_RS15320	COG1196	nuclear chromosome segregation
EKM74_RS15325	COG0552	protein localization to endoplasmic reticulum
EKM74_RS15335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EKM74_RS15390	COG2348	transferase activity, transferring amino-acyl groups
EKM74_RS15395	COG0758	DNA mediated transformation
EKM74_RS15495	COG0195	Participates in both transcription termination and antitermination
EKM74_RS15500	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EKM74_RS15525	COG0196	riboflavin kinase activity
EKM74_RS15555	COG2188	Transcriptional regulator
EKM74_RS15560	COG0612	Peptidase, M16
EKM74_RS15565	COG0612	Peptidase, M16
EKM74_RS15570	COG0300	oxidoreductase activity
EKM74_RS15590	COG1058	Belongs to the CinA family
EKM74_RS15590	COG1546	Belongs to the CinA family
EKM74_RS15610	COG1692	metallophosphoesterase
EKM74_RS15615	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EKM74_RS15615	COG0674	pyruvate-flavodoxin oxidoreductase activity
EKM74_RS15620	COG1013	pyruvate-flavodoxin oxidoreductase activity
EKM74_RS15655	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EKM74_RS15660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EKM74_RS15685	COG1923	regulation of RNA biosynthetic process
EKM74_RS15695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKM74_RS15700	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EKM74_RS15705	COG0789	Transcriptional regulator
EKM74_RS15785	COG1131	(ABC) transporter
EKM74_RS15800	COG2197	response regulator
EKM74_RS15810	COG1525	nuclease
EKM74_RS15835	COG0527	aspartate kinase activity
EKM74_RS15840	COG0460	homoserine dehydrogenase
EKM74_RS15845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EKM74_RS15870	COG0833	amino acid
EKM74_RS15900	COG2340	Cysteine-rich secretory protein family
EKM74_RS15935	COG4846	Membrane protein involved in cytochrome C biogenesis
EKM74_RS15955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EKM74_RS15970	COG0824	Thioesterase
EKM74_RS16010	COG1115	amino acid carrier protein
EKM74_RS16025	COG0628	permease
EKM74_RS16050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKM74_RS16060	COG1363	Peptidase, m42
EKM74_RS16065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKM74_RS16070	COG0512	Glutamine amidotransferase of anthranilate synthase
EKM74_RS16115	COG0561	phosphatase activity
EKM74_RS16160	COG0704	Plays a role in the regulation of phosphate uptake
EKM74_RS16170	COG0581	inorganic phosphate transmembrane transporter activity
EKM74_RS16175	COG0573	inorganic phosphate transmembrane transporter activity
EKM74_RS16195	COG0488	(ABC) transporter
EKM74_RS16205	COG0527	aspartate kinase activity
EKM74_RS16210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate