locus-tag	class	description
E3S62_RS00020	COG0740	serine-type endopeptidase activity
E3S62_RS00070	COG0739	heme binding
E3S62_RS00115	COG1388	LysM domain
E3S62_RS00115	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S62_RS00125	COG1388	LysM domain
E3S62_RS00125	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S62_RS00175	COG1725	Transcriptional regulator
E3S62_RS00190	COG1131	(ABC) transporter
E3S62_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
E3S62_RS00255	COG1335	isochorismatase
E3S62_RS00265	COG0471	metal ion transport
E3S62_RS00275	COG0077	Prephenate dehydratase
E3S62_RS00285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3S62_RS00320	COG4496	protein, YerC YecD
E3S62_RS00340	COG4851	CamS sex pheromone cAM373 precursor
E3S62_RS00455	COG1295	ribonuclease BN
E3S62_RS00475	COG2309	aminopeptidase activity
E3S62_RS00480	COG1607	acyl-coa hydrolase
E3S62_RS00485	COG0535	radical SAM domain protein
E3S62_RS00490	COG4974	Belongs to the 'phage' integrase family
E3S62_RS00565	COG0629	single-stranded DNA binding
E3S62_RS00585	COG1484	DNA-dependent DNA replication
E3S62_RS00795	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S62_RS00795	COG1388	LysM domain
E3S62_RS00830	COG1134	teichoic acid transport
E3S62_RS00830	COG1388	LysM domain
E3S62_RS00840	COG1988	membrane-bound metal-dependent
E3S62_RS00845	COG1194	a g-specific adenine glycosylase
E3S62_RS00865	COG4129	membrane
E3S62_RS00875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3S62_RS00880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S62_RS01045	COG0765	amino acid transport
E3S62_RS01050	COG1126	abc transporter atp-binding protein
E3S62_RS01055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3S62_RS01085	COG0564	pseudouridine synthase activity
E3S62_RS01090	COG2203	Gaf domain
E3S62_RS01090	COG4585	Histidine kinase
E3S62_RS01095	COG2197	response regulator
E3S62_RS01120	COG0420	3'-5' exonuclease activity
E3S62_RS01150	COG0537	adenosine 5'-monophosphoramidase activity
E3S62_RS01155	COG1131	(ABC) transporter
E3S62_RS01345	COG2816	NAD+ diphosphatase activity
E3S62_RS01350	COG1506	peptidase
E3S62_RS01370	COG0656	L-ascorbic acid biosynthetic process
E3S62_RS01380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E3S62_RS01390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3S62_RS01425	COG4193	domain, Protein
E3S62_RS01425	COG3266	domain, Protein
E3S62_RS01425	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S62_RS01445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S62_RS01445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S62_RS01475	COG2267	carboxylic ester hydrolase activity
E3S62_RS01480	COG1846	Transcriptional regulator
E3S62_RS01485	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3S62_RS01490	COG1242	4 iron, 4 sulfur cluster binding
E3S62_RS01495	COG2814	Major facilitator Superfamily
E3S62_RS01515	COG2081	HI0933 family
E3S62_RS01520	COG2244	polysaccharide biosynthetic process
E3S62_RS01525	COG1187	pseudouridine synthase activity
E3S62_RS01545	COG0510	thiamine kinase activity
E3S62_RS01555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S62_RS01565	COG1363	Peptidase, m42
E3S62_RS01570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S62_RS01580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3S62_RS01585	COG1674	ftsk spoiiie
E3S62_RS01610	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E3S62_RS01610	COG1605	Chorismate mutase
E3S62_RS01630	COG0454	-acetyltransferase
E3S62_RS01635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S62_RS01670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3S62_RS01675	COG0204	Acyl-transferase
E3S62_RS01680	COG1263	PTS System
E3S62_RS01680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S62_RS01695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S62_RS01700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E3S62_RS01705	COG1764	response to oxidative stress
E3S62_RS01710	COG0584	glycerophosphoryl diester phosphodiesterase
E3S62_RS01725	COG1956	GAF domain-containing protein
E3S62_RS01740	COG1104	cysteine desulfurase activity
E3S62_RS01750	COG0730	response to heat
E3S62_RS01760	COG0827	DNA restriction-modification system
E3S62_RS01800	COG4109	DRTGG domain
E3S62_RS01805	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3S62_RS01815	COG0281	malic enzyme
E3S62_RS01840	COG1113	amino acid transport
E3S62_RS01845	COG0372	Belongs to the citrate synthase family
E3S62_RS01855	COG0745	RESPONSE REGULATOR receiver
E3S62_RS01860	COG5002	protein histidine kinase activity
E3S62_RS01870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S62_RS01870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S62_RS01875	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3S62_RS01900	COG1484	DNA-dependent DNA replication
E3S62_RS01915	COG0833	amino acid
E3S62_RS01935	COG4112	unkown
E3S62_RS01970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3S62_RS01985	COG0113	porphobilinogen synthase activity
E3S62_RS02005	COG2818	Glycosylase
E3S62_RS02015	COG0285	dihydrofolate synthase activity
E3S62_RS02020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E3S62_RS02065	COG2868	ribosomal protein
E3S62_RS02105	COG1862	Preprotein translocase
E3S62_RS02110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S62_RS02110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S62_RS02115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3S62_RS02115	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E3S62_RS02160	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3S62_RS02165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3S62_RS02170	COG1959	2 iron, 2 sulfur cluster binding
E3S62_RS02185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S62_RS02190	COG1104	cysteine desulfurase activity
E3S62_RS02205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3S62_RS02255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3S62_RS02260	COG1984	allophanate hydrolase subunit 2
E3S62_RS02265	COG0511	ligase activity, forming carbon-carbon bonds
E3S62_RS02270	COG0439	Biotin carboxylase
E3S62_RS02280	COG1914	H( )-stimulated, divalent metal cation uptake system
E3S62_RS02285	COG3177	Filamentation induced by cAMP protein fic
E3S62_RS02305	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E3S62_RS02310	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E3S62_RS02320	COG1534	Rna-binding protein
E3S62_RS02330	COG1713	HD superfamily hydrolase involved in NAD metabolism
E3S62_RS02335	COG0799	negative regulation of ribosome biogenesis
E3S62_RS02340	COG2226	methyltransferase
E3S62_RS02345	COG2183	response to ionizing radiation
E3S62_RS02350	COG2131	deaminase
E3S62_RS02355	COG2333	competence protein COMEC
E3S62_RS02355	COG0658	competence protein
E3S62_RS02360	COG1466	dna polymerase III delta subunit
E3S62_RS02375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3S62_RS02405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3S62_RS02410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3S62_RS02420	COG1030	water channel activity
E3S62_RS02435	COG1702	phosphate starvation-inducible protein PhoH
E3S62_RS02450	COG0295	cytidine deaminase activity
E3S62_RS02470	COG0517	IMP dehydrogenase activity
E3S62_RS02485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3S62_RS02490	COG2384	SAM-dependent methyltransferase
E3S62_RS02500	COG0513	Belongs to the DEAD box helicase family
E3S62_RS02510	COG1121	(ABC) transporter
E3S62_RS02515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S62_RS02520	COG0735	belongs to the Fur family
E3S62_RS02540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3S62_RS02550	COG4483	Protein conserved in bacteria
E3S62_RS02555	COG1940	carbohydrate kinase activity
E3S62_RS02560	COG0011	TIGRFAM Protein of
E3S62_RS02565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S62_RS02570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3S62_RS02575	COG1459	type II secretion system
E3S62_RS02580	COG4537	Required for transformation and DNA binding
E3S62_RS02625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3S62_RS02630	COG0095	Lipoate-protein ligase
E3S62_RS02645	COG0006	proline dipeptidase activity
E3S62_RS02655	COG0511	ligase activity, forming carbon-carbon bonds
E3S62_RS02660	COG0439	Biotin carboxylase
E3S62_RS02665	COG1302	Protein conserved in bacteria
E3S62_RS02695	COG0497	DNA recombination
E3S62_RS02700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S62_RS02705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E3S62_RS02710	COG0022	dehydrogenase e1 component
E3S62_RS02715	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3S62_RS02725	COG4129	membrane
E3S62_RS02735	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3S62_RS02755	COG1609	Transcriptional regulator
E3S62_RS02760	COG0366	Alpha amylase catalytic
E3S62_RS02770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3S62_RS02785	COG4221	oxidoreductase activity
E3S62_RS02795	COG0667	Aldo Keto reductase
E3S62_RS02800	COG0494	nUDIX hydrolase
E3S62_RS02805	COG0735	belongs to the Fur family
E3S62_RS02830	COG1187	pseudouridine synthase activity
E3S62_RS02835	COG0745	RESPONSE REGULATOR receiver
E3S62_RS02840	COG5002	protein histidine kinase activity
E3S62_RS02865	COG1141	Ferredoxin
E3S62_RS02875	COG0514	ATP-dependent DNA helicase (RecQ)
E3S62_RS02890	COG0492	ferredoxin-NADP+ reductase activity
E3S62_RS02945	COG0142	geranyltranstransferase activity
E3S62_RS02985	COG4347	Protein of unknown function (DUF1405)
E3S62_RS02990	COG2738	Putative neutral zinc metallopeptidase
E3S62_RS02995	COG1694	Mazg nucleotide pyrophosphohydrolase
E3S62_RS03000	COG0438	transferase activity, transferring glycosyl groups
E3S62_RS03025	COG3935	DnaD domain protein
E3S62_RS03030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3S62_RS03040	COG4499	WXG100 protein secretion system (Wss), protein YukC
E3S62_RS03040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3S62_RS03070	COG0116	Belongs to the methyltransferase superfamily
E3S62_RS03085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3S62_RS03090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S62_RS03105	COG0531	amino acid
E3S62_RS03135	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3S62_RS03175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S62_RS03210	COG0671	phosphoesterase, PA-phosphatase related
E3S62_RS03270	COG4548	von Willebrand factor, type A
E3S62_RS03310	COG2808	Putative FMN-binding domain
E3S62_RS03345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3S62_RS03350	COG0527	aspartate kinase activity
E3S62_RS03355	COG0488	(ABC) transporter
E3S62_RS03370	COG0573	inorganic phosphate transmembrane transporter activity
E3S62_RS03375	COG0581	inorganic phosphate transmembrane transporter activity
E3S62_RS03385	COG0704	Plays a role in the regulation of phosphate uptake
E3S62_RS03425	COG0561	phosphatase activity
E3S62_RS03430	COG2348	transferase activity, transferring amino-acyl groups
E3S62_RS03465	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S62_RS03470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S62_RS03475	COG1363	Peptidase, m42
E3S62_RS03485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3S62_RS03495	COG1316	TRANSCRIPTIONal
E3S62_RS03500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S62_RS03510	COG0628	permease
E3S62_RS03525	COG1115	amino acid carrier protein
E3S62_RS03535	COG0187	DNA topoisomerase II activity
E3S62_RS03550	COG0824	Thioesterase
E3S62_RS03560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S62_RS03580	COG4846	Membrane protein involved in cytochrome C biogenesis
E3S62_RS03615	COG2340	Cysteine-rich secretory protein family
E3S62_RS03645	COG0833	amino acid
E3S62_RS03670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3S62_RS03675	COG0460	homoserine dehydrogenase
E3S62_RS03680	COG0527	aspartate kinase activity
E3S62_RS03695	COG1525	nuclease
E3S62_RS03705	COG2197	response regulator
E3S62_RS03720	COG1131	(ABC) transporter
E3S62_RS03765	COG1783	phage Terminase large subunit
E3S62_RS03875	COG0789	Transcriptional regulator
E3S62_RS03880	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E3S62_RS03895	COG1923	regulation of RNA biosynthetic process
E3S62_RS03920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3S62_RS03925	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3S62_RS03960	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3S62_RS03965	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3S62_RS03965	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3S62_RS03970	COG1692	metallophosphoesterase
E3S62_RS03990	COG1546	Belongs to the CinA family
E3S62_RS03990	COG1058	Belongs to the CinA family
E3S62_RS04010	COG0300	oxidoreductase activity
E3S62_RS04015	COG0612	Peptidase, M16
E3S62_RS04020	COG0612	Peptidase, M16
E3S62_RS04025	COG2188	Transcriptional regulator
E3S62_RS04050	COG0196	riboflavin kinase activity
E3S62_RS04075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E3S62_RS04080	COG0195	Participates in both transcription termination and antitermination
E3S62_RS04175	COG0758	DNA mediated transformation
E3S62_RS04180	COG2348	transferase activity, transferring amino-acyl groups
E3S62_RS04235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3S62_RS04245	COG0552	protein localization to endoplasmic reticulum
E3S62_RS04250	COG1196	nuclear chromosome segregation
E3S62_RS04295	COG1302	Protein conserved in bacteria
E3S62_RS04310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3S62_RS04325	COG0631	protein serine/threonine phosphatase activity
E3S62_RS04335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3S62_RS04335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3S62_RS04350	COG2314	TM2 domain
E3S62_RS04360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3S62_RS04365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3S62_RS04425	COG2233	PERMEase
E3S62_RS04435	COG0564	pseudouridine synthase activity
E3S62_RS04445	COG2514	catechol 2,3-dioxygenase activity
E3S62_RS04455	COG3599	regulation of cell shape
E3S62_RS04465	COG0762	integral membrane protein
E3S62_RS04475	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3S62_RS04485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3S62_RS04490	COG0849	cell division
E3S62_RS04515	COG4839	cell division protein FtsL
E3S62_RS04540	COG1011	Hydrolase
E3S62_RS04575	COG1288	antiporter activity
E3S62_RS04675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3S62_RS04680	COG1053	succinate dehydrogenase
E3S62_RS04685	COG2009	succinate dehydrogenase
E3S62_RS04710	COG1796	DNA polymerase
E3S62_RS04710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3S62_RS04740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3S62_RS04755	COG4509	Sortase family
E3S62_RS04810	COG0742	ribosomal rna small subunit methyltransferase
E3S62_RS04825	COG0584	glycerophosphoryl diester phosphodiesterase
E3S62_RS04830	COG3679	Belongs to the UPF0342 family
E3S62_RS04855	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3S62_RS04860	COG0772	Belongs to the SEDS family
E3S62_RS04870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E3S62_RS04890	COG0483	inositol monophosphate 1-phosphatase activity
E3S62_RS04915	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3S62_RS04920	COG1177	transmembrane transport
E3S62_RS04925	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3S62_RS04990	COG0569	domain protein
E3S62_RS04995	COG1294	oxidase, subunit
E3S62_RS05000	COG1271	oxidase subunit
E3S62_RS05005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3S62_RS05025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3S62_RS05045	COG4721	ABC-type cobalt transport system, permease component
E3S62_RS05050	COG4172	Belongs to the ABC transporter superfamily
E3S62_RS05055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E3S62_RS05095	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3S62_RS05110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3S62_RS05155	COG1316	TRANSCRIPTIONal
E3S62_RS05165	COG2153	protein acetylation
E3S62_RS05185	COG3594	Acyltransferase
E3S62_RS05190	COG0436	Aminotransferase
E3S62_RS05225	COG1169	isochorismate synthase
E3S62_RS05235	COG1575	Belongs to the MenA family. Type 1 subfamily
E3S62_RS05240	COG0456	acetyltransferase
E3S62_RS05245	COG2314	TM2 domain
E3S62_RS05255	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S62_RS05305	COG4873	Protein conserved in bacteria
E3S62_RS05320	COG4903	ComK protein
E3S62_RS05335	COG0737	Belongs to the 5'-nucleotidase family
E3S62_RS05340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S62_RS05350	COG0861	Integral membrane protein TerC family
E3S62_RS05390	COG1115	amino acid carrier protein
E3S62_RS05395	COG0628	permease
E3S62_RS05405	COG0569	domain protein
E3S62_RS05405	COG0475	glutathione-regulated potassium exporter activity
E3S62_RS05410	COG2239	Acts as a magnesium transporter
E3S62_RS05415	COG0564	pseudouridine synthase activity
E3S62_RS05425	COG2357	RelA SpoT domain protein
E3S62_RS05440	COG2346	COG2346, Truncated hemoglobins
E3S62_RS05450	COG1164	Oligoendopeptidase f
E3S62_RS05475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S62_RS05480	COG0601	transmembrane transport
E3S62_RS05485	COG4608	Belongs to the ABC transporter superfamily
E3S62_RS05490	COG0444	Belongs to the ABC transporter superfamily
E3S62_RS05495	COG0747	negative chemotaxis
E3S62_RS05500	COG4166	transmembrane transport
E3S62_RS05505	COG4608	Belongs to the ABC transporter superfamily
E3S62_RS05510	COG0444	Belongs to the ABC transporter superfamily
E3S62_RS05515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S62_RS05520	COG0601	transmembrane transport
E3S62_RS05550	COG1881	PFAM PEBP family protein
E3S62_RS05575	COG0561	phosphatase activity
E3S62_RS05595	COG1074	ATP-dependent DNA helicase activity
E3S62_RS05615	COG0398	Pfam SNARE associated Golgi protein
E3S62_RS05635	COG0584	glycerophosphoryl diester phosphodiesterase
E3S62_RS05650	COG1902	pentaerythritol trinitrate reductase activity
E3S62_RS05655	COG1098	S1 RNA binding domain
E3S62_RS05710	COG2050	protein possibly involved in aromatic compounds catabolism
E3S62_RS05715	COG2056	Na+-H+ antiporter family
E3S62_RS05720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3S62_RS05730	COG0316	Belongs to the HesB IscA family
E3S62_RS05740	COG1252	NADH dehydrogenase
E3S62_RS05745	COG4837	Protein of unknown function (DUF1462)
E3S62_RS05750	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3S62_RS05755	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E3S62_RS05765	COG1696	Membrane protein involved in D-alanine export
E3S62_RS05795	COG2445	Protein of unknown function DUF86
E3S62_RS05805	COG4470	Protein conserved in bacteria
E3S62_RS05820	COG0730	response to heat
E3S62_RS05825	COG1801	Protein of unknown function DUF72
E3S62_RS05835	COG1253	flavin adenine dinucleotide binding
E3S62_RS05855	COG0822	iron-sulfur transferase activity
E3S62_RS05865	COG0719	Fe-S assembly protein
E3S62_RS05870	COG0396	ATPase activity
E3S62_RS05885	COG1464	Belongs to the NlpA lipoprotein family
E3S62_RS05890	COG2011	ABC-type metal ion transport system permease component
E3S62_RS05905	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S62_RS05910	COG3878	Protein conserved in bacteria
E3S62_RS05925	COG1393	Belongs to the ArsC family
E3S62_RS05930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S62_RS05955	COG1279	arginine transmembrane transporter activity
E3S62_RS05960	COG0406	alpha-ribazole phosphatase activity
E3S62_RS06000	COG1278	Cold shock
E3S62_RS06065	COG0557	exoribonuclease II activity
E3S62_RS06070	COG1647	Serine aminopeptidase, S33
E3S62_RS06075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S62_RS06125	COG0281	malic enzyme
E3S62_RS06140	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3S62_RS06195	COG1388	LysM domain
E3S62_RS06195	COG3942	CHAP domain
E3S62_RS06220	COG1040	competence protein
E3S62_RS06225	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E3S62_RS06235	COG1739	Uncharacterized protein family UPF0029
E3S62_RS06240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3S62_RS06295	COG4607	ABC-type enterochelin transport system periplasmic component
E3S62_RS06300	COG4604	ABC transporter, ATP-binding protein
E3S62_RS06305	COG4605	iron ion homeostasis
E3S62_RS06310	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S62_RS06315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S62_RS06320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S62_RS06340	COG3104	oligopeptide transport
E3S62_RS06365	COG1174	glycine betaine transport
E3S62_RS06370	COG1125	glycine betaine transport
E3S62_RS06370	COG0517	IMP dehydrogenase activity
E3S62_RS06375	COG0514	ATP-dependent DNA helicase (RecQ)
E3S62_RS06380	COG0488	(ABC) transporter
E3S62_RS06410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S62_RS06415	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S62_RS06415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3S62_RS06425	COG0720	synthase
E3S62_RS06460	COG0463	Glycosyl transferase, family 2
E3S62_RS06465	COG0656	L-ascorbic acid biosynthetic process
E3S62_RS06470	COG1253	flavin adenine dinucleotide binding
E3S62_RS06475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3S62_RS06480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S62_RS06480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S62_RS06480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S62_RS06485	COG1105	Belongs to the carbohydrate kinase PfkB family
E3S62_RS06490	COG1349	DNA-binding transcription factor activity
E3S62_RS06495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3S62_RS06530	COG0471	metal ion transport
E3S62_RS06540	COG4989	oxidoreductase activity
E3S62_RS06545	COG0523	cobalamin synthesis protein
E3S62_RS06550	COG1846	Transcriptional regulator
E3S62_RS06555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3S62_RS06560	COG4988	ABC transporter
E3S62_RS06580	COG1611	Belongs to the LOG family
E3S62_RS06610	COG2839	Protein conserved in bacteria
E3S62_RS06615	COG2814	Major facilitator Superfamily
E3S62_RS06620	COG0583	DNA-binding transcription factor activity
E3S62_RS06650	COG1917	Cupin 2, conserved barrel domain protein
E3S62_RS06650	COG4977	sequence-specific DNA binding
E3S62_RS06660	COG3942	CHAP domain
E3S62_RS06660	COG1388	LysM domain
E3S62_RS06665	COG0306	phosphate transporter
E3S62_RS06670	COG1392	Phosphate transport regulator
E3S62_RS06675	COG0577	efflux transmembrane transporter activity
E3S62_RS06680	COG1136	(ABC) transporter
E3S62_RS06715	COG3949	Membrane
E3S62_RS06725	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E3S62_RS06735	COG2376	Dihydroxyacetone kinase
E3S62_RS06740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S62_RS06745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S62_RS06750	COG1120	ATPase activity
E3S62_RS06755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E3S62_RS06765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S62_RS06770	COG1132	(ABC) transporter
E3S62_RS06775	COG1686	Belongs to the peptidase S11 family
E3S62_RS06780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3S62_RS06790	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S62_RS06795	COG1682	transport, permease protein
E3S62_RS06805	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
E3S62_RS06815	COG1321	iron dependent repressor
E3S62_RS06820	COG1121	(ABC) transporter
E3S62_RS06825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S62_RS06925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S62_RS06930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S62_RS06965	COG1078	dGTPase activity
E3S62_RS06975	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S62_RS06980	COG0667	Aldo Keto reductase
E3S62_RS07025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S62_RS07045	COG0083	homoserine kinase activity
E3S62_RS07050	COG0095	Lipoate-protein ligase
E3S62_RS07155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3S62_RS07180	COG4932	domain protein
E3S62_RS07195	COG0561	phosphatase activity
E3S62_RS07205	COG1428	Deoxynucleoside kinase
E3S62_RS07210	COG1428	Deoxynucleoside kinase
E3S62_RS07245	COG1473	amidohydrolase
E3S62_RS07275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E3S62_RS07285	COG2813	Specifically methylates the guanine in position
E3S62_RS07315	COG0250	Participates in transcription elongation, termination and antitermination
E3S62_RS07320	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S62_RS07345	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3S62_RS07365	COG4956	integral membrane protein (PIN domain superfamily)
E3S62_RS07370	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3S62_RS07385	COG3880	PFAM UvrB UvrC protein
E3S62_RS07395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S62_RS07410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S62_RS07505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3S62_RS07530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3S62_RS07545	COG1098	S1 RNA binding domain
E3S62_RS07555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3S62_RS07560	COG3956	TIGRFAM MazG family protein
E3S62_RS07565	COG2244	polysaccharide biosynthetic process
E3S62_RS07605	COG0251	oxidation-reduction process
E3S62_RS07610	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3S62_RS07620	COG4466	Protein conserved in bacteria
E3S62_RS07630	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S62_RS07635	COG0084	hydrolase, TatD family'
E3S62_RS07645	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3S62_RS07655	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3S62_RS07665	COG1774	PSP1 C-terminal conserved region
E3S62_RS07670	COG0470	DNA polymerase III
E3S62_RS07675	COG3870	Protein conserved in bacteria
E3S62_RS07685	COG1982	Orn Lys Arg decarboxylase major
E3S62_RS07715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E3S62_RS07720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3S62_RS07740	COG2188	Transcriptional regulator
E3S62_RS07745	COG0366	Alpha amylase catalytic
E3S62_RS07750	COG1263	PTS System
E3S62_RS07750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S62_RS07760	COG0493	'glutamate synthase
E3S62_RS07765	COG0069	glutamate synthase activity
E3S62_RS07765	COG0067	glutamate synthase
E3S62_RS07765	COG0070	glutamate synthase
E3S62_RS07770	COG0583	DNA-binding transcription factor activity
E3S62_RS07805	COG1464	Belongs to the NlpA lipoprotein family
E3S62_RS07810	COG2011	ABC-type metal ion transport system permease component
E3S62_RS07820	COG0626	cystathionine gamma-synthase activity
E3S62_RS07825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3S62_RS07830	COG0733	neurotransmitter:sodium symporter activity
E3S62_RS07840	COG1647	Serine aminopeptidase, S33
E3S62_RS07855	COG5609	conserved protein (DUF2294)
E3S62_RS07865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3S62_RS07890	COG0523	cobalamin synthesis protein
E3S62_RS08005	COG3759	membrane
E3S62_RS08010	COG1683	Conserved Protein
E3S62_RS08085	COG2233	PERMEase
E3S62_RS08115	COG1823	symporter activity
E3S62_RS08220	COG0012	GTP binding
E3S62_RS08225	COG4481	Protein conserved in bacteria
E3S62_RS08230	COG0668	transmembrane transport
E3S62_RS08235	COG1475	DNA binding
E3S62_RS08240	COG0626	cystathionine gamma-synthase activity
E3S62_RS08245	COG0626	cystathionine gamma-synthase activity
E3S62_RS08250	COG0646	methionine synthase
E3S62_RS08250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3S62_RS08280	COG1131	(ABC) transporter
E3S62_RS08290	COG1476	TRANSCRIPTIONal
E3S62_RS08300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3S62_RS08310	COG0672	)-iron permease
E3S62_RS08315	COG2837	iron assimilation
E3S62_RS08320	COG2822	iron ion transport
E3S62_RS08325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S62_RS08335	COG0431	NADPH-dependent FMN reductase
E3S62_RS08340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S62_RS08345	COG0346	lactoylglutathione lyase activity
E3S62_RS08350	COG2271	Major facilitator Superfamily
E3S62_RS08370	COG3711	transcriptional antiterminator
E3S62_RS08375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S62_RS08385	COG3037	sugar-specific permease SgaT UlaA
E3S62_RS08410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S62_RS08460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3S62_RS08490	COG1136	(ABC) transporter
E3S62_RS08495	COG0577	efflux transmembrane transporter activity
E3S62_RS08500	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E3S62_RS08505	COG1114	Component of the transport system for branched-chain amino acids
E3S62_RS08535	COG3316	Transposase and inactivated derivatives
E3S62_RS08560	COG1192	Involved in chromosome partitioning
E3S62_RS08585	COG0456	acetyltransferase
E3S62_RS08595	COG2226	methyltransferase
E3S62_RS08610	COG1309	transcriptional regulator
E3S62_RS08620	COG1131	(ABC) transporter
E3S62_RS08705	COG1136	(ABC) transporter
E3S62_RS08705	COG0577	efflux transmembrane transporter activity
E3S62_RS08760	COG3316	Transposase and inactivated derivatives
E3S62_RS08875	COG3942	CHAP domain
E3S62_RS08875	COG1388	LysM domain
E3S62_RS08905	COG1131	(ABC) transporter
E3S62_RS08910	COG0739	heme binding
E3S62_RS08955	COG2226	methyltransferase
E3S62_RS08960	COG2723	6-phospho-beta-galactosidase activity
E3S62_RS08965	COG1263	PTS System
E3S62_RS08965	COG2190	(PTS) system
E3S62_RS08965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S62_RS08970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S62_RS09005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S62_RS09010	COG1063	alcohol dehydrogenase
E3S62_RS09020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S62_RS09025	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S62_RS09030	COG1063	alcohol dehydrogenase
E3S62_RS09035	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E3S62_RS09040	COG1063	alcohol dehydrogenase
E3S62_RS09050	COG1063	alcohol dehydrogenase
E3S62_RS09055	COG3775	system Galactitol-specific IIC component
E3S62_RS09060	COG3414	Phosphotransferase system galactitol-specific IIB component
E3S62_RS09075	COG1957	nucleoside hydrolase
E3S62_RS09080	COG2190	(PTS) system
E3S62_RS09080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S62_RS09080	COG1263	PTS System
E3S62_RS09105	COG3189	MarR family transcriptional regulator
E3S62_RS09110	COG0747	negative chemotaxis
E3S62_RS09115	COG1073	alpha beta
E3S62_RS09120	COG0702	epimerase
E3S62_RS09145	COG0318	PFAM AMP-dependent synthetase and ligase
E3S62_RS09150	COG1960	acyl-CoA dehydrogenase activity
E3S62_RS09160	COG0183	Belongs to the thiolase family
E3S62_RS09215	COG1755	Isoprenylcysteine carboxyl methyltransferase
E3S62_RS09225	COG0673	inositol 2-dehydrogenase activity
E3S62_RS09230	COG0673	inositol 2-dehydrogenase activity
E3S62_RS09235	COG3833	ABC-type maltose transport systems, permease component
E3S62_RS09250	COG3842	ATPase activity
E3S62_RS09270	COG0405	Gamma-glutamyltransferase
E3S62_RS09280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S62_RS09310	COG1737	Transcriptional regulator
E3S62_RS09340	COG3961	Belongs to the TPP enzyme family
E3S62_RS09345	COG1335	isochorismatase
E3S62_RS09350	COG1114	Component of the transport system for branched-chain amino acids
E3S62_RS09400	COG1960	acyl-CoA dehydrogenase activity
E3S62_RS09405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3S62_RS09440	COG2832	Protein of unknown function (DUF454)
E3S62_RS09450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S62_RS09455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3S62_RS09465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S62_RS09495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S62_RS09505	COG1086	Polysaccharide biosynthesis protein
E3S62_RS09530	COG1012	belongs to the aldehyde dehydrogenase family
E3S62_RS09530	COG1454	alcohol dehydrogenase
E3S62_RS09540	COG0737	Belongs to the 5'-nucleotidase family
E3S62_RS09560	COG3639	organic phosphonate transmembrane transporter activity
E3S62_RS09580	COG2814	Major facilitator Superfamily
E3S62_RS09585	COG0813	purine-nucleoside phosphorylase activity
E3S62_RS09615	COG0438	transferase activity, transferring glycosyl groups
E3S62_RS09620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S62_RS09625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3S62_RS09650	COG1475	DNA binding
E3S62_RS09655	COG0019	diaminopimelate decarboxylase activity
E3S62_RS09665	COG4264	IucA IucC family
E3S62_RS09670	COG4264	IucA IucC family
E3S62_RS09675	COG2814	Major facilitator Superfamily
E3S62_RS09680	COG4264	IucA IucC family
E3S62_RS09685	COG2423	ornithine cyclodeaminase activity
E3S62_RS09695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S62_RS09700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S62_RS09705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S62_RS09720	COG1620	l-lactate permease
E3S62_RS09735	COG0697	spore germination
E3S62_RS09740	COG4716	Myosin-crossreactive antigen
E3S62_RS09745	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3S62_RS09755	COG1473	amidohydrolase
E3S62_RS09770	COG0823	Involved in the tonB-independent uptake of proteins
E3S62_RS09780	COG2226	methyltransferase
E3S62_RS09790	COG1073	alpha beta
E3S62_RS09805	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S62_RS09835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3S62_RS09840	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E3S62_RS09845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3S62_RS09850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E3S62_RS09855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E3S62_RS09860	COG0151	Belongs to the GarS family
E3S62_RS09885	COG2814	Major facilitator Superfamily
E3S62_RS09895	COG0456	acetyltransferase
E3S62_RS09900	COG1522	sequence-specific DNA binding
E3S62_RS09930	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E3S62_RS10010	COG2602	Beta-lactamase
E3S62_RS10010	COG4219	Peptidase M56
E3S62_RS10020	COG2030	dehydratase
E3S62_RS10025	COG0584	glycerophosphoryl diester phosphodiesterase
E3S62_RS10030	COG3425	synthase
E3S62_RS10035	COG3316	Transposase and inactivated derivatives
E3S62_RS10055	COG0737	Belongs to the 5'-nucleotidase family
E3S62_RS10060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3S62_RS10070	COG4863	YycH protein
E3S62_RS10100	COG0305	Participates in initiation and elongation during chromosome replication
E3S62_RS10110	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E3S62_RS10120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3S62_RS10145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3S62_RS10165	COG2501	S4 domain
E3S62_RS10205	COG1475	DNA binding
E3S62_RS10225	COG1278	Cold shock
E3S62_RS10240	COG0577	efflux transmembrane transporter activity
E3S62_RS10245	COG1136	(ABC) transporter
E3S62_RS10260	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3S62_RS10270	COG2962	Rard protein
E3S62_RS10275	COG0471	metal ion transport
E3S62_RS10335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3S62_RS10375	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
E3S62_RS10390	COG1215	transferase activity, transferring glycosyl groups
E3S62_RS10395	COG1309	transcriptional regulator
E3S62_RS10425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S62_RS10450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S62_RS10460	COG0201	protein transport
E3S62_RS10470	COG1073	alpha beta
E3S62_RS10485	COG0438	transferase activity, transferring glycosyl groups
E3S62_RS10500	COG1535	isochorismatase
E3S62_RS10500	COG3433	isochorismatase activity
E3S62_RS10505	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3S62_RS10505	COG3942	CHAP domain
E3S62_RS10515	COG1482	cell wall glycoprotein biosynthetic process
E3S62_RS10520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S62_RS10520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S62_RS10520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S62_RS10525	COG3711	transcriptional antiterminator
E3S62_RS10525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S62_RS10545	COG1438	arginine binding
E3S62_RS10555	COG2235	arginine
E3S62_RS10580	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E3S62_RS10580	COG4932	domain protein
E3S62_RS10580	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E3S62_RS10580	COG4932	domain protein
E3S62_RS10590	COG1846	Transcriptional regulator
E3S62_RS10600	COG1785	Belongs to the alkaline phosphatase family
E3S62_RS10610	COG0745	RESPONSE REGULATOR receiver
E3S62_RS10615	COG2205	protein histidine kinase activity
E3S62_RS10620	COG1136	(ABC) transporter
E3S62_RS10640	COG0386	Belongs to the glutathione peroxidase family
E3S62_RS10650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3S62_RS10665	COG2851	Citrate transporter
E3S62_RS10690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S62_RS10695	COG1510	regulation of RNA biosynthetic process
E3S62_RS10725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S62_RS10755	COG0531	amino acid
E3S62_RS10765	COG3527	Alpha-acetolactate decarboxylase
E3S62_RS10770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S62_RS10820	COG0167	dihydroorotate dehydrogenase activity
E3S62_RS10930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
E3S62_RS10930	COG2755	lipolytic protein G-D-S-L family
E3S62_RS10965	COG0436	Aminotransferase
E3S62_RS10980	COG2217	Heavy metal translocating P-type atpase
E3S62_RS11010	COG2409	Drug exporters of the RND superfamily
E3S62_RS11035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3S62_RS11040	COG3425	synthase
E3S62_RS11050	COG3942	CHAP domain
E3S62_RS11060	COG0583	DNA-binding transcription factor activity
E3S62_RS11075	COG0028	Belongs to the TPP enzyme family
E3S62_RS11095	COG0657	acetylesterase activity
E3S62_RS11100	COG0697	spore germination
E3S62_RS11115	COG1760	l-serine dehydratase
E3S62_RS11120	COG1760	l-serine dehydratase
E3S62_RS11140	COG3764	Sortase (surface protein transpeptidase)
E3S62_RS11150	COG1131	(ABC) transporter
E3S62_RS11155	COG0561	phosphatase activity
E3S62_RS11170	COG2514	catechol 2,3-dioxygenase activity
E3S62_RS11180	COG1846	Transcriptional regulator
E3S62_RS11185	COG0346	lactoylglutathione lyase activity
E3S62_RS11190	COG0400	carboxylic ester hydrolase activity
E3S62_RS11210	COG1131	(ABC) transporter
E3S62_RS11220	COG0586	Pfam SNARE associated Golgi protein
E3S62_RS11225	COG2271	Major facilitator Superfamily
E3S62_RS11235	COG4876	unkown
E3S62_RS11240	COG2357	RelA SpoT domain protein
E3S62_RS11245	COG0789	Transcriptional regulator
E3S62_RS11250	COG1802	Transcriptional regulator
E3S62_RS11255	COG1070	Carbohydrate kinase
E3S62_RS11300	COG0494	nUDIX hydrolase
E3S62_RS11395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3S62_RS11400	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3S62_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
E3S62_RS11410	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3S62_RS11430	COG0747	negative chemotaxis
E3S62_RS11435	COG0601	transmembrane transport
E3S62_RS11440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S62_RS11450	COG1124	(ABC) transporter
E3S62_RS11465	COG0069	glutamate synthase activity
E3S62_RS11470	COG4808	Protein conserved in bacteria
E3S62_RS11475	COG1363	Peptidase, m42
E3S62_RS11480	COG4619	ABC transporter
E3S62_RS11485	COG0390	transport system, permease component
E3S62_RS11490	COG2814	Major facilitator Superfamily
E3S62_RS11495	COG2272	Belongs to the type-B carboxylesterase lipase family
E3S62_RS11505	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E3S62_RS11525	COG1174	glycine betaine transport
E3S62_RS11535	COG1174	glycine betaine transport
E3S62_RS11545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S62_RS11560	COG0531	amino acid
E3S62_RS11570	COG1113	amino acid transport
E3S62_RS11590	COG2814	Major facilitator Superfamily
E3S62_RS11600	COG1929	Belongs to the glycerate kinase type-1 family
E3S62_RS11625	COG1132	(ABC) transporter
E3S62_RS11635	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3S62_RS11640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3S62_RS11650	COG0156	8-amino-7-oxononanoate synthase activity
E3S62_RS11690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E3S62_RS11710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3S62_RS11715	COG0765	amino acid transport
E3S62_RS11720	COG1126	abc transporter atp-binding protein
E3S62_RS11740	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S62_RS11740	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3S62_RS11755	COG2116	formate transmembrane transporter activity
E3S62_RS11760	COG0454	-acetyltransferase
E3S62_RS11770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3S62_RS11775	COG2146	nitrite reductase [NAD(P)H] activity
E3S62_RS11785	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3S62_RS11790	COG1140	nitrate reductase beta subunit
E3S62_RS11800	COG2181	nitrate reductase activity
E3S62_RS11820	COG0789	Transcriptional regulator
E3S62_RS11860	COG3871	stress protein (general stress protein 26)
E3S62_RS11875	COG1263	PTS System
E3S62_RS11875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S62_RS11890	COG1511	domain protein
E3S62_RS11915	COG0604	alcohol dehydrogenase
E3S62_RS11935	COG1620	l-lactate permease
E3S62_RS11950	COG1131	(ABC) transporter
E3S62_RS12010	COG2814	Major facilitator Superfamily
E3S62_RS12020	COG1566	PFAM secretion protein HlyD family protein
E3S62_RS12025	COG2814	Major facilitator Superfamily
E3S62_RS12035	COG0657	acetylesterase activity
E3S62_RS12050	COG0598	Magnesium transport protein CorA
E3S62_RS12060	COG0786	glutamate:sodium symporter activity
E3S62_RS12070	COG3152	Membrane
E3S62_RS12075	COG4152	abc transporter atp-binding protein
E3S62_RS12080	COG1668	transmembrane transport
E3S62_RS12100	COG2258	MOSC domain
E3S62_RS12120	COG0583	DNA-binding transcription factor activity
E3S62_RS12135	COG1473	amidohydrolase
E3S62_RS12140	COG1028	Short-chain dehydrogenase reductase Sdr
E3S62_RS12160	COG1737	Transcriptional regulator
E3S62_RS12165	COG1263	PTS System
E3S62_RS12165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S62_RS12175	COG0385	Bile acid
E3S62_RS12180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3S62_RS12200	COG1113	amino acid transport
E3S62_RS12285	COG1757	Na H antiporter
E3S62_RS12355	COG4413	Urea transporter
E3S62_RS12360	COG1960	acyl-CoA dehydrogenase activity
E3S62_RS12375	COG1268	BioY protein
E3S62_RS12390	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3S62_RS12395	COG4149	molybdate abc transporter
E3S62_RS12400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3S62_RS12405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3S62_RS12425	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3S62_RS12485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3S62_RS12530	COG2252	PERMEase
E3S62_RS12645	COG0201	protein transport
E3S62_RS12730	COG0028	Belongs to the TPP enzyme family
E3S62_RS12735	COG3527	Alpha-acetolactate decarboxylase
E3S62_RS12750	COG0438	transferase activity, transferring glycosyl groups
E3S62_RS12765	COG5492	domain, Protein
E3S62_RS12775	COG0789	Transcriptional regulator
E3S62_RS12780	COG0656	L-ascorbic acid biosynthetic process
E3S62_RS12840	COG2130	NADP-dependent
E3S62_RS12855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S62_RS12880	COG2814	Major facilitator Superfamily
E3S62_RS12885	COG4264	IucA IucC family
E3S62_RS12890	COG3457	Alanine racemase
E3S62_RS12900	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S62_RS12905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S62_RS12910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S62_RS12925	COG1988	membrane-bound metal-dependent
E3S62_RS12935	COG1272	protein, Hemolysin III
E3S62_RS12950	COG2814	Major facilitator Superfamily
E3S62_RS12955	COG0489	protein tyrosine kinase activity
E3S62_RS13015	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E3S62_RS13045	COG3711	transcriptional antiterminator
E3S62_RS13060	COG1119	ATPase activity
E3S62_RS13065	COG0561	phosphatase activity
E3S62_RS13085	COG0640	Transcriptional regulator
E3S62_RS13090	COG0702	epimerase
E3S62_RS13095	COG1482	cell wall glycoprotein biosynthetic process
E3S62_RS13115	COG0783	Belongs to the Dps family
E3S62_RS13120	COG0813	purine-nucleoside phosphorylase activity
E3S62_RS13165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S62_RS13205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3S62_RS13225	COG2890	protein-(glutamine-N5) methyltransferase activity
E3S62_RS13230	COG0009	L-threonylcarbamoyladenylate synthase
E3S62_RS13255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S62_RS13330	COG0629	single-stranded DNA binding
E3S62_RS13365	COG1418	mRNA catabolic process
E3S62_RS13375	COG1937	Protein conserved in bacteria
E3S62_RS13390	COG0772	Belongs to the SEDS family
E3S62_RS13400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3S62_RS13410	COG0745	RESPONSE REGULATOR receiver
E3S62_RS13415	COG2205	protein histidine kinase activity
E3S62_RS13445	COG3428	Bacterial PH domain
E3S62_RS13475	COG2208	phosphoserine phosphatase activity
E3S62_RS13480	COG1366	Belongs to the anti-sigma-factor antagonist family
E3S62_RS13490	COG1191	sigma factor activity
E3S62_RS13495	COG2183	response to ionizing radiation
E3S62_RS13570	COG0028	Belongs to the TPP enzyme family
E3S62_RS13585	COG0802	atpase or kinase
E3S62_RS13590	COG1214	PFAM Peptidase M22, glycoprotease
E3S62_RS13595	COG0456	acetyltransferase
E3S62_RS13605	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E3S62_RS13615	COG0488	(ABC) transporter
E3S62_RS13625	COG2391	methyltransferase activity
E3S62_RS13630	COG0425	Belongs to the sulfur carrier protein TusA family
E3S62_RS13635	COG0004	ammonium transporteR
E3S62_RS13640	COG1609	Transcriptional regulator
E3S62_RS13645	COG1621	beta-fructofuranosidase activity
E3S62_RS13650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3S62_RS13720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S62_RS13770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
