locus-tag	class	description
E3S99_RS00020	COG0740	serine-type endopeptidase activity
E3S99_RS00075	COG0739	heme binding
E3S99_RS00120	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S99_RS00120	COG1388	LysM domain
E3S99_RS00130	COG1388	LysM domain
E3S99_RS00130	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S99_RS00180	COG1725	Transcriptional regulator
E3S99_RS00195	COG1131	(ABC) transporter
E3S99_RS00245	COG1012	belongs to the aldehyde dehydrogenase family
E3S99_RS00260	COG1335	isochorismatase
E3S99_RS00270	COG0471	metal ion transport
E3S99_RS00280	COG0077	Prephenate dehydratase
E3S99_RS00290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3S99_RS00325	COG4496	protein, YerC YecD
E3S99_RS00345	COG4851	CamS sex pheromone cAM373 precursor
E3S99_RS00460	COG1295	ribonuclease BN
E3S99_RS00480	COG2309	aminopeptidase activity
E3S99_RS00485	COG1607	acyl-coa hydrolase
E3S99_RS00490	COG0535	radical SAM domain protein
E3S99_RS00495	COG4974	Belongs to the 'phage' integrase family
E3S99_RS00595	COG1484	DNA-dependent DNA replication
E3S99_RS00825	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S99_RS00825	COG1388	LysM domain
E3S99_RS00860	COG1388	LysM domain
E3S99_RS00860	COG1134	teichoic acid transport
E3S99_RS00870	COG1988	membrane-bound metal-dependent
E3S99_RS00875	COG1194	a g-specific adenine glycosylase
E3S99_RS00895	COG4129	membrane
E3S99_RS00905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3S99_RS00910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S99_RS01075	COG0765	amino acid transport
E3S99_RS01080	COG1126	abc transporter atp-binding protein
E3S99_RS01085	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3S99_RS01115	COG0564	pseudouridine synthase activity
E3S99_RS01120	COG4585	Histidine kinase
E3S99_RS01120	COG2203	Gaf domain
E3S99_RS01125	COG2197	response regulator
E3S99_RS01150	COG0420	3'-5' exonuclease activity
E3S99_RS01180	COG0537	adenosine 5'-monophosphoramidase activity
E3S99_RS01185	COG1131	(ABC) transporter
E3S99_RS01375	COG2816	NAD+ diphosphatase activity
E3S99_RS01380	COG1506	peptidase
E3S99_RS01400	COG0656	L-ascorbic acid biosynthetic process
E3S99_RS01410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E3S99_RS01420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3S99_RS01455	COG3266	domain, Protein
E3S99_RS01455	COG4193	domain, Protein
E3S99_RS01455	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S99_RS01475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S99_RS01475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S99_RS01505	COG2267	carboxylic ester hydrolase activity
E3S99_RS01510	COG1846	Transcriptional regulator
E3S99_RS01515	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3S99_RS01520	COG1242	4 iron, 4 sulfur cluster binding
E3S99_RS01525	COG2814	Major facilitator Superfamily
E3S99_RS01545	COG2081	HI0933 family
E3S99_RS01550	COG2244	polysaccharide biosynthetic process
E3S99_RS01555	COG1187	pseudouridine synthase activity
E3S99_RS01575	COG0510	thiamine kinase activity
E3S99_RS01585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S99_RS01595	COG1363	Peptidase, m42
E3S99_RS01600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S99_RS01610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3S99_RS01615	COG1674	ftsk spoiiie
E3S99_RS01640	COG1605	Chorismate mutase
E3S99_RS01640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E3S99_RS01660	COG0454	-acetyltransferase
E3S99_RS01665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S99_RS01700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3S99_RS01705	COG0204	Acyl-transferase
E3S99_RS01710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S99_RS01710	COG1263	PTS System
E3S99_RS01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S99_RS01730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E3S99_RS01735	COG1764	response to oxidative stress
E3S99_RS01740	COG0584	glycerophosphoryl diester phosphodiesterase
E3S99_RS01755	COG1956	GAF domain-containing protein
E3S99_RS01770	COG1104	cysteine desulfurase activity
E3S99_RS01780	COG0730	response to heat
E3S99_RS01790	COG0827	DNA restriction-modification system
E3S99_RS01830	COG4109	DRTGG domain
E3S99_RS01835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3S99_RS01845	COG0281	malic enzyme
E3S99_RS01870	COG1113	amino acid transport
E3S99_RS01875	COG0372	Belongs to the citrate synthase family
E3S99_RS01885	COG0745	RESPONSE REGULATOR receiver
E3S99_RS01890	COG5002	protein histidine kinase activity
E3S99_RS01900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S99_RS01900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S99_RS01905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3S99_RS01930	COG1484	DNA-dependent DNA replication
E3S99_RS01945	COG0833	amino acid
E3S99_RS01965	COG4112	unkown
E3S99_RS02000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3S99_RS02015	COG0113	porphobilinogen synthase activity
E3S99_RS02035	COG2818	Glycosylase
E3S99_RS02045	COG0285	dihydrofolate synthase activity
E3S99_RS02050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E3S99_RS02095	COG2868	ribosomal protein
E3S99_RS02135	COG1862	Preprotein translocase
E3S99_RS02140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S99_RS02140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S99_RS02145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3S99_RS02145	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E3S99_RS02190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3S99_RS02195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3S99_RS02200	COG1959	2 iron, 2 sulfur cluster binding
E3S99_RS02215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S99_RS02220	COG1104	cysteine desulfurase activity
E3S99_RS02235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3S99_RS02285	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3S99_RS02290	COG1984	allophanate hydrolase subunit 2
E3S99_RS02295	COG0511	ligase activity, forming carbon-carbon bonds
E3S99_RS02300	COG0439	Biotin carboxylase
E3S99_RS02310	COG1914	H( )-stimulated, divalent metal cation uptake system
E3S99_RS02315	COG3177	Filamentation induced by cAMP protein fic
E3S99_RS02335	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E3S99_RS02340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E3S99_RS02350	COG1534	Rna-binding protein
E3S99_RS02360	COG1713	HD superfamily hydrolase involved in NAD metabolism
E3S99_RS02365	COG0799	negative regulation of ribosome biogenesis
E3S99_RS02370	COG2226	methyltransferase
E3S99_RS02375	COG2183	response to ionizing radiation
E3S99_RS02380	COG2131	deaminase
E3S99_RS02385	COG2333	competence protein COMEC
E3S99_RS02385	COG0658	competence protein
E3S99_RS02390	COG1466	dna polymerase III delta subunit
E3S99_RS02405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3S99_RS02435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3S99_RS02440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3S99_RS02450	COG1030	water channel activity
E3S99_RS02465	COG1702	phosphate starvation-inducible protein PhoH
E3S99_RS02480	COG0295	cytidine deaminase activity
E3S99_RS02500	COG0517	IMP dehydrogenase activity
E3S99_RS02515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3S99_RS02520	COG2384	SAM-dependent methyltransferase
E3S99_RS02530	COG0513	Belongs to the DEAD box helicase family
E3S99_RS02540	COG1121	(ABC) transporter
E3S99_RS02545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S99_RS02550	COG0735	belongs to the Fur family
E3S99_RS02570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3S99_RS02580	COG4483	Protein conserved in bacteria
E3S99_RS02585	COG1940	carbohydrate kinase activity
E3S99_RS02590	COG0011	TIGRFAM Protein of
E3S99_RS02595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S99_RS02605	COG1459	type II secretion system
E3S99_RS02610	COG4537	Required for transformation and DNA binding
E3S99_RS02655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3S99_RS02660	COG0095	Lipoate-protein ligase
E3S99_RS02675	COG0006	proline dipeptidase activity
E3S99_RS02685	COG0511	ligase activity, forming carbon-carbon bonds
E3S99_RS02690	COG0439	Biotin carboxylase
E3S99_RS02695	COG1302	Protein conserved in bacteria
E3S99_RS02725	COG0497	DNA recombination
E3S99_RS02730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S99_RS02735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E3S99_RS02740	COG0022	dehydrogenase e1 component
E3S99_RS02745	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3S99_RS02755	COG4129	membrane
E3S99_RS02765	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3S99_RS02785	COG1609	Transcriptional regulator
E3S99_RS02790	COG0366	Alpha amylase catalytic
E3S99_RS02800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3S99_RS02815	COG4221	oxidoreductase activity
E3S99_RS02825	COG0667	Aldo Keto reductase
E3S99_RS02830	COG0494	nUDIX hydrolase
E3S99_RS02835	COG0735	belongs to the Fur family
E3S99_RS02860	COG1187	pseudouridine synthase activity
E3S99_RS02865	COG0745	RESPONSE REGULATOR receiver
E3S99_RS02870	COG5002	protein histidine kinase activity
E3S99_RS02895	COG1141	Ferredoxin
E3S99_RS02905	COG0514	ATP-dependent DNA helicase (RecQ)
E3S99_RS02920	COG0492	ferredoxin-NADP+ reductase activity
E3S99_RS02975	COG0142	geranyltranstransferase activity
E3S99_RS03015	COG4347	Protein of unknown function (DUF1405)
E3S99_RS03020	COG2738	Putative neutral zinc metallopeptidase
E3S99_RS03025	COG1694	Mazg nucleotide pyrophosphohydrolase
E3S99_RS03030	COG0438	transferase activity, transferring glycosyl groups
E3S99_RS03055	COG3935	DnaD domain protein
E3S99_RS03060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3S99_RS03070	COG4499	WXG100 protein secretion system (Wss), protein YukC
E3S99_RS03070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3S99_RS03100	COG0116	Belongs to the methyltransferase superfamily
E3S99_RS03115	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3S99_RS03120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S99_RS03135	COG0531	amino acid
E3S99_RS03165	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3S99_RS03205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S99_RS03240	COG0671	phosphoesterase, PA-phosphatase related
E3S99_RS03300	COG4548	von Willebrand factor, type A
E3S99_RS03340	COG2808	Putative FMN-binding domain
E3S99_RS03375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3S99_RS03380	COG0527	aspartate kinase activity
E3S99_RS03385	COG0488	(ABC) transporter
E3S99_RS03400	COG0573	inorganic phosphate transmembrane transporter activity
E3S99_RS03405	COG0581	inorganic phosphate transmembrane transporter activity
E3S99_RS03415	COG0704	Plays a role in the regulation of phosphate uptake
E3S99_RS03455	COG0561	phosphatase activity
E3S99_RS03460	COG2348	transferase activity, transferring amino-acyl groups
E3S99_RS03495	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S99_RS03500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S99_RS03505	COG1363	Peptidase, m42
E3S99_RS03515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3S99_RS03525	COG1316	TRANSCRIPTIONal
E3S99_RS03530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S99_RS03540	COG0628	permease
E3S99_RS03555	COG1115	amino acid carrier protein
E3S99_RS03565	COG0187	DNA topoisomerase II activity
E3S99_RS03580	COG0824	Thioesterase
E3S99_RS03590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S99_RS03610	COG4846	Membrane protein involved in cytochrome C biogenesis
E3S99_RS03645	COG2340	Cysteine-rich secretory protein family
E3S99_RS03675	COG0833	amino acid
E3S99_RS03700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3S99_RS03705	COG0460	homoserine dehydrogenase
E3S99_RS03710	COG0527	aspartate kinase activity
E3S99_RS03725	COG1525	nuclease
E3S99_RS03735	COG2197	response regulator
E3S99_RS03750	COG1131	(ABC) transporter
E3S99_RS03790	COG1783	phage Terminase large subunit
E3S99_RS03900	COG0789	Transcriptional regulator
E3S99_RS03905	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E3S99_RS03920	COG1923	regulation of RNA biosynthetic process
E3S99_RS03945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3S99_RS03950	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3S99_RS03985	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3S99_RS03990	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3S99_RS03990	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3S99_RS03995	COG1692	metallophosphoesterase
E3S99_RS04015	COG1058	Belongs to the CinA family
E3S99_RS04015	COG1546	Belongs to the CinA family
E3S99_RS04035	COG0300	oxidoreductase activity
E3S99_RS04040	COG0612	Peptidase, M16
E3S99_RS04045	COG0612	Peptidase, M16
E3S99_RS04050	COG2188	Transcriptional regulator
E3S99_RS04075	COG0196	riboflavin kinase activity
E3S99_RS04100	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E3S99_RS04105	COG0195	Participates in both transcription termination and antitermination
E3S99_RS04200	COG0758	DNA mediated transformation
E3S99_RS04205	COG2348	transferase activity, transferring amino-acyl groups
E3S99_RS04260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3S99_RS04270	COG0552	protein localization to endoplasmic reticulum
E3S99_RS04275	COG1196	nuclear chromosome segregation
E3S99_RS04320	COG1302	Protein conserved in bacteria
E3S99_RS04335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3S99_RS04350	COG0631	protein serine/threonine phosphatase activity
E3S99_RS04360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3S99_RS04360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3S99_RS04375	COG2314	TM2 domain
E3S99_RS04385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3S99_RS04390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3S99_RS04450	COG2233	PERMEase
E3S99_RS04460	COG0564	pseudouridine synthase activity
E3S99_RS04470	COG2514	catechol 2,3-dioxygenase activity
E3S99_RS04480	COG3599	regulation of cell shape
E3S99_RS04490	COG0762	integral membrane protein
E3S99_RS04500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3S99_RS04510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3S99_RS04515	COG0849	cell division
E3S99_RS04540	COG4839	cell division protein FtsL
E3S99_RS04565	COG1011	Hydrolase
E3S99_RS04600	COG1288	antiporter activity
E3S99_RS04700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3S99_RS04705	COG1053	succinate dehydrogenase
E3S99_RS04710	COG2009	succinate dehydrogenase
E3S99_RS04735	COG1796	DNA polymerase
E3S99_RS04735	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3S99_RS04765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3S99_RS04780	COG4509	Sortase family
E3S99_RS04835	COG0742	ribosomal rna small subunit methyltransferase
E3S99_RS04850	COG0584	glycerophosphoryl diester phosphodiesterase
E3S99_RS04855	COG3679	Belongs to the UPF0342 family
E3S99_RS04880	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3S99_RS04885	COG0772	Belongs to the SEDS family
E3S99_RS04895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E3S99_RS04915	COG0483	inositol monophosphate 1-phosphatase activity
E3S99_RS04940	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3S99_RS04945	COG1177	transmembrane transport
E3S99_RS04950	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3S99_RS05015	COG0569	domain protein
E3S99_RS05020	COG1294	oxidase, subunit
E3S99_RS05025	COG1271	oxidase subunit
E3S99_RS05030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3S99_RS05050	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3S99_RS05070	COG4721	ABC-type cobalt transport system, permease component
E3S99_RS05075	COG4172	Belongs to the ABC transporter superfamily
E3S99_RS05080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E3S99_RS05120	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3S99_RS05135	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3S99_RS05180	COG1316	TRANSCRIPTIONal
E3S99_RS05190	COG2153	protein acetylation
E3S99_RS05210	COG3594	Acyltransferase
E3S99_RS05215	COG0436	Aminotransferase
E3S99_RS05250	COG1169	isochorismate synthase
E3S99_RS05260	COG1575	Belongs to the MenA family. Type 1 subfamily
E3S99_RS05265	COG0456	acetyltransferase
E3S99_RS05270	COG2314	TM2 domain
E3S99_RS05280	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S99_RS05330	COG4873	Protein conserved in bacteria
E3S99_RS05345	COG4903	ComK protein
E3S99_RS05360	COG0737	Belongs to the 5'-nucleotidase family
E3S99_RS05365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S99_RS05375	COG0861	Integral membrane protein TerC family
E3S99_RS05415	COG1115	amino acid carrier protein
E3S99_RS05420	COG0628	permease
E3S99_RS05430	COG0569	domain protein
E3S99_RS05430	COG0475	glutathione-regulated potassium exporter activity
E3S99_RS05435	COG2239	Acts as a magnesium transporter
E3S99_RS05440	COG0564	pseudouridine synthase activity
E3S99_RS05450	COG2357	RelA SpoT domain protein
E3S99_RS05465	COG2346	COG2346, Truncated hemoglobins
E3S99_RS05475	COG1164	Oligoendopeptidase f
E3S99_RS05500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S99_RS05505	COG0601	transmembrane transport
E3S99_RS05510	COG4608	Belongs to the ABC transporter superfamily
E3S99_RS05515	COG0444	Belongs to the ABC transporter superfamily
E3S99_RS05520	COG0747	negative chemotaxis
E3S99_RS05525	COG4166	transmembrane transport
E3S99_RS05530	COG4608	Belongs to the ABC transporter superfamily
E3S99_RS05535	COG0444	Belongs to the ABC transporter superfamily
E3S99_RS05540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S99_RS05545	COG0601	transmembrane transport
E3S99_RS05575	COG1881	PFAM PEBP family protein
E3S99_RS05600	COG0561	phosphatase activity
E3S99_RS05620	COG1074	ATP-dependent DNA helicase activity
E3S99_RS05640	COG0398	Pfam SNARE associated Golgi protein
E3S99_RS05660	COG0584	glycerophosphoryl diester phosphodiesterase
E3S99_RS05675	COG1902	pentaerythritol trinitrate reductase activity
E3S99_RS05680	COG1098	S1 RNA binding domain
E3S99_RS05735	COG2050	protein possibly involved in aromatic compounds catabolism
E3S99_RS05740	COG2056	Na+-H+ antiporter family
E3S99_RS05745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3S99_RS05755	COG0316	Belongs to the HesB IscA family
E3S99_RS05765	COG1252	NADH dehydrogenase
E3S99_RS05770	COG4837	Protein of unknown function (DUF1462)
E3S99_RS05775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3S99_RS05780	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E3S99_RS05790	COG1696	Membrane protein involved in D-alanine export
E3S99_RS05820	COG2445	Protein of unknown function DUF86
E3S99_RS05830	COG4470	Protein conserved in bacteria
E3S99_RS05845	COG0730	response to heat
E3S99_RS05850	COG1801	Protein of unknown function DUF72
E3S99_RS05860	COG1253	flavin adenine dinucleotide binding
E3S99_RS05880	COG0822	iron-sulfur transferase activity
E3S99_RS05890	COG0719	Fe-S assembly protein
E3S99_RS05895	COG0396	ATPase activity
E3S99_RS05910	COG1464	Belongs to the NlpA lipoprotein family
E3S99_RS05915	COG2011	ABC-type metal ion transport system permease component
E3S99_RS05930	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S99_RS05935	COG3878	Protein conserved in bacteria
E3S99_RS05950	COG1393	Belongs to the ArsC family
E3S99_RS05955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S99_RS05980	COG1279	arginine transmembrane transporter activity
E3S99_RS05985	COG0406	alpha-ribazole phosphatase activity
E3S99_RS06025	COG1278	Cold shock
E3S99_RS06090	COG0557	exoribonuclease II activity
E3S99_RS06095	COG1647	Serine aminopeptidase, S33
E3S99_RS06100	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S99_RS06150	COG0281	malic enzyme
E3S99_RS06165	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3S99_RS06220	COG1388	LysM domain
E3S99_RS06220	COG3942	CHAP domain
E3S99_RS06245	COG1040	competence protein
E3S99_RS06250	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E3S99_RS06260	COG1739	Uncharacterized protein family UPF0029
E3S99_RS06265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3S99_RS06320	COG4607	ABC-type enterochelin transport system periplasmic component
E3S99_RS06325	COG4604	ABC transporter, ATP-binding protein
E3S99_RS06330	COG4605	iron ion homeostasis
E3S99_RS06335	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S99_RS06340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S99_RS06345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S99_RS06365	COG3104	oligopeptide transport
E3S99_RS06390	COG1174	glycine betaine transport
E3S99_RS06395	COG1125	glycine betaine transport
E3S99_RS06395	COG0517	IMP dehydrogenase activity
E3S99_RS06400	COG0514	ATP-dependent DNA helicase (RecQ)
E3S99_RS06405	COG0488	(ABC) transporter
E3S99_RS06435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S99_RS06440	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S99_RS06440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3S99_RS06450	COG0720	synthase
E3S99_RS06485	COG0463	Glycosyl transferase, family 2
E3S99_RS06490	COG0656	L-ascorbic acid biosynthetic process
E3S99_RS06495	COG1253	flavin adenine dinucleotide binding
E3S99_RS06500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3S99_RS06505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S99_RS06505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S99_RS06505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S99_RS06510	COG1105	Belongs to the carbohydrate kinase PfkB family
E3S99_RS06515	COG1349	DNA-binding transcription factor activity
E3S99_RS06520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3S99_RS06555	COG0471	metal ion transport
E3S99_RS06565	COG4989	oxidoreductase activity
E3S99_RS06570	COG0523	cobalamin synthesis protein
E3S99_RS06575	COG1846	Transcriptional regulator
E3S99_RS06580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3S99_RS06585	COG4988	ABC transporter
E3S99_RS06605	COG1611	Belongs to the LOG family
E3S99_RS06635	COG2839	Protein conserved in bacteria
E3S99_RS06640	COG2814	Major facilitator Superfamily
E3S99_RS06645	COG0583	DNA-binding transcription factor activity
E3S99_RS06675	COG4977	sequence-specific DNA binding
E3S99_RS06675	COG1917	Cupin 2, conserved barrel domain protein
E3S99_RS06685	COG1388	LysM domain
E3S99_RS06685	COG3942	CHAP domain
E3S99_RS06690	COG0306	phosphate transporter
E3S99_RS06695	COG1392	Phosphate transport regulator
E3S99_RS06700	COG0577	efflux transmembrane transporter activity
E3S99_RS06705	COG1136	(ABC) transporter
E3S99_RS06740	COG3949	Membrane
E3S99_RS06750	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E3S99_RS06760	COG2376	Dihydroxyacetone kinase
E3S99_RS06765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S99_RS06770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S99_RS06775	COG1120	ATPase activity
E3S99_RS06780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E3S99_RS06790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S99_RS06795	COG1132	(ABC) transporter
E3S99_RS06800	COG1686	Belongs to the peptidase S11 family
E3S99_RS06805	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3S99_RS06815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S99_RS06820	COG1682	transport, permease protein
E3S99_RS06830	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
E3S99_RS06840	COG1321	iron dependent repressor
E3S99_RS06845	COG1121	(ABC) transporter
E3S99_RS06850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S99_RS06950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S99_RS06955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S99_RS06990	COG1078	dGTPase activity
E3S99_RS07000	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S99_RS07005	COG0667	Aldo Keto reductase
E3S99_RS07050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S99_RS07070	COG0083	homoserine kinase activity
E3S99_RS07075	COG0095	Lipoate-protein ligase
E3S99_RS07180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3S99_RS07205	COG4932	domain protein
E3S99_RS07220	COG0561	phosphatase activity
E3S99_RS07230	COG1428	Deoxynucleoside kinase
E3S99_RS07235	COG1428	Deoxynucleoside kinase
E3S99_RS07270	COG1473	amidohydrolase
E3S99_RS07300	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E3S99_RS07310	COG2813	Specifically methylates the guanine in position
E3S99_RS07340	COG0250	Participates in transcription elongation, termination and antitermination
E3S99_RS07345	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S99_RS07370	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3S99_RS07390	COG4956	integral membrane protein (PIN domain superfamily)
E3S99_RS07395	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3S99_RS07410	COG3880	PFAM UvrB UvrC protein
E3S99_RS07420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S99_RS07435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S99_RS07535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3S99_RS07560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3S99_RS07575	COG1098	S1 RNA binding domain
E3S99_RS07585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3S99_RS07590	COG3956	TIGRFAM MazG family protein
E3S99_RS07595	COG2244	polysaccharide biosynthetic process
E3S99_RS07635	COG0251	oxidation-reduction process
E3S99_RS07640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3S99_RS07650	COG4466	Protein conserved in bacteria
E3S99_RS07660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S99_RS07665	COG0084	hydrolase, TatD family'
E3S99_RS07675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3S99_RS07685	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3S99_RS07695	COG1774	PSP1 C-terminal conserved region
E3S99_RS07700	COG0470	DNA polymerase III
E3S99_RS07705	COG3870	Protein conserved in bacteria
E3S99_RS07715	COG1982	Orn Lys Arg decarboxylase major
E3S99_RS07745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E3S99_RS07750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3S99_RS07770	COG2188	Transcriptional regulator
E3S99_RS07775	COG0366	Alpha amylase catalytic
E3S99_RS07780	COG1263	PTS System
E3S99_RS07780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S99_RS07790	COG0493	'glutamate synthase
E3S99_RS07795	COG0067	glutamate synthase
E3S99_RS07795	COG0069	glutamate synthase activity
E3S99_RS07795	COG0070	glutamate synthase
E3S99_RS07800	COG0583	DNA-binding transcription factor activity
E3S99_RS07835	COG1464	Belongs to the NlpA lipoprotein family
E3S99_RS07840	COG2011	ABC-type metal ion transport system permease component
E3S99_RS07850	COG0626	cystathionine gamma-synthase activity
E3S99_RS07855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3S99_RS07860	COG0733	neurotransmitter:sodium symporter activity
E3S99_RS07870	COG1647	Serine aminopeptidase, S33
E3S99_RS07885	COG5609	conserved protein (DUF2294)
E3S99_RS07895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3S99_RS07920	COG0523	cobalamin synthesis protein
E3S99_RS08035	COG3759	membrane
E3S99_RS08040	COG1683	Conserved Protein
E3S99_RS08115	COG2233	PERMEase
E3S99_RS08145	COG1823	symporter activity
E3S99_RS08250	COG0012	GTP binding
E3S99_RS08255	COG4481	Protein conserved in bacteria
E3S99_RS08260	COG0668	transmembrane transport
E3S99_RS08265	COG1475	DNA binding
E3S99_RS08270	COG0626	cystathionine gamma-synthase activity
E3S99_RS08275	COG0626	cystathionine gamma-synthase activity
E3S99_RS08280	COG0646	methionine synthase
E3S99_RS08280	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3S99_RS08310	COG1131	(ABC) transporter
E3S99_RS08320	COG1476	TRANSCRIPTIONal
E3S99_RS08330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3S99_RS08340	COG0672	)-iron permease
E3S99_RS08345	COG2837	iron assimilation
E3S99_RS08350	COG2822	iron ion transport
E3S99_RS08355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S99_RS08365	COG0431	NADPH-dependent FMN reductase
E3S99_RS08370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S99_RS08375	COG0346	lactoylglutathione lyase activity
E3S99_RS08380	COG2271	Major facilitator Superfamily
E3S99_RS08400	COG3711	transcriptional antiterminator
E3S99_RS08405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S99_RS08415	COG3037	sugar-specific permease SgaT UlaA
E3S99_RS08440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S99_RS08490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3S99_RS08520	COG1136	(ABC) transporter
E3S99_RS08525	COG0577	efflux transmembrane transporter activity
E3S99_RS08530	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E3S99_RS08535	COG1114	Component of the transport system for branched-chain amino acids
E3S99_RS08565	COG3316	Transposase and inactivated derivatives
E3S99_RS08590	COG1192	Involved in chromosome partitioning
E3S99_RS08615	COG0456	acetyltransferase
E3S99_RS08625	COG2226	methyltransferase
E3S99_RS08640	COG1309	transcriptional regulator
E3S99_RS08650	COG1131	(ABC) transporter
E3S99_RS08735	COG1136	(ABC) transporter
E3S99_RS08735	COG0577	efflux transmembrane transporter activity
E3S99_RS08790	COG3316	Transposase and inactivated derivatives
E3S99_RS08905	COG1388	LysM domain
E3S99_RS08905	COG3942	CHAP domain
E3S99_RS08935	COG1131	(ABC) transporter
E3S99_RS08940	COG0739	heme binding
E3S99_RS08985	COG2226	methyltransferase
E3S99_RS08990	COG2723	6-phospho-beta-galactosidase activity
E3S99_RS08995	COG2190	(PTS) system
E3S99_RS08995	COG1263	PTS System
E3S99_RS08995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S99_RS09000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S99_RS09035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S99_RS09040	COG1063	alcohol dehydrogenase
E3S99_RS09050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S99_RS09055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S99_RS09060	COG1063	alcohol dehydrogenase
E3S99_RS09065	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E3S99_RS09070	COG1063	alcohol dehydrogenase
E3S99_RS09080	COG1063	alcohol dehydrogenase
E3S99_RS09085	COG3775	system Galactitol-specific IIC component
E3S99_RS09090	COG3414	Phosphotransferase system galactitol-specific IIB component
E3S99_RS09105	COG1957	nucleoside hydrolase
E3S99_RS09110	COG1263	PTS System
E3S99_RS09110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S99_RS09110	COG2190	(PTS) system
E3S99_RS09135	COG3189	MarR family transcriptional regulator
E3S99_RS09140	COG0747	negative chemotaxis
E3S99_RS09145	COG1073	alpha beta
E3S99_RS09150	COG0702	epimerase
E3S99_RS09175	COG0318	PFAM AMP-dependent synthetase and ligase
E3S99_RS09180	COG1960	acyl-CoA dehydrogenase activity
E3S99_RS09190	COG0183	Belongs to the thiolase family
E3S99_RS09245	COG1755	Isoprenylcysteine carboxyl methyltransferase
E3S99_RS09255	COG0673	inositol 2-dehydrogenase activity
E3S99_RS09260	COG0673	inositol 2-dehydrogenase activity
E3S99_RS09265	COG3833	ABC-type maltose transport systems, permease component
E3S99_RS09270	COG1175	transmembrane transport
E3S99_RS09280	COG3842	ATPase activity
E3S99_RS09300	COG0405	Gamma-glutamyltransferase
E3S99_RS09310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S99_RS09340	COG1737	Transcriptional regulator
E3S99_RS09370	COG3961	Belongs to the TPP enzyme family
E3S99_RS09375	COG1335	isochorismatase
E3S99_RS09380	COG1114	Component of the transport system for branched-chain amino acids
E3S99_RS09430	COG1960	acyl-CoA dehydrogenase activity
E3S99_RS09435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3S99_RS09470	COG2832	Protein of unknown function (DUF454)
E3S99_RS09480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S99_RS09485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3S99_RS09495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S99_RS09525	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S99_RS09535	COG1086	Polysaccharide biosynthesis protein
E3S99_RS09560	COG1012	belongs to the aldehyde dehydrogenase family
E3S99_RS09560	COG1454	alcohol dehydrogenase
E3S99_RS09570	COG0737	Belongs to the 5'-nucleotidase family
E3S99_RS09590	COG3639	organic phosphonate transmembrane transporter activity
E3S99_RS09610	COG2814	Major facilitator Superfamily
E3S99_RS09615	COG0813	purine-nucleoside phosphorylase activity
E3S99_RS09645	COG0438	transferase activity, transferring glycosyl groups
E3S99_RS09650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S99_RS09655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3S99_RS09685	COG1475	DNA binding
E3S99_RS09690	COG0019	diaminopimelate decarboxylase activity
E3S99_RS09700	COG4264	IucA IucC family
E3S99_RS09705	COG4264	IucA IucC family
E3S99_RS09710	COG2814	Major facilitator Superfamily
E3S99_RS09715	COG4264	IucA IucC family
E3S99_RS09720	COG2423	ornithine cyclodeaminase activity
E3S99_RS09730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S99_RS09735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S99_RS09740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S99_RS09755	COG1620	l-lactate permease
E3S99_RS09770	COG0697	spore germination
E3S99_RS09775	COG4716	Myosin-crossreactive antigen
E3S99_RS09780	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3S99_RS09790	COG1473	amidohydrolase
E3S99_RS09805	COG0823	Involved in the tonB-independent uptake of proteins
E3S99_RS09815	COG2226	methyltransferase
E3S99_RS09825	COG1073	alpha beta
E3S99_RS09840	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S99_RS09885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E3S99_RS09890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3S99_RS09895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E3S99_RS09900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E3S99_RS09905	COG0151	Belongs to the GarS family
E3S99_RS09930	COG2814	Major facilitator Superfamily
E3S99_RS09940	COG0456	acetyltransferase
E3S99_RS09945	COG1522	sequence-specific DNA binding
E3S99_RS09965	COG0737	Belongs to the 5'-nucleotidase family
E3S99_RS09970	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3S99_RS09980	COG4863	YycH protein
E3S99_RS10010	COG0305	Participates in initiation and elongation during chromosome replication
E3S99_RS10020	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E3S99_RS10030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3S99_RS10055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3S99_RS10075	COG2501	S4 domain
E3S99_RS10115	COG1475	DNA binding
E3S99_RS10135	COG1278	Cold shock
E3S99_RS10150	COG0577	efflux transmembrane transporter activity
E3S99_RS10155	COG1136	(ABC) transporter
E3S99_RS10170	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3S99_RS10180	COG2962	Rard protein
E3S99_RS10185	COG0471	metal ion transport
E3S99_RS10245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3S99_RS10285	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
E3S99_RS10300	COG1215	transferase activity, transferring glycosyl groups
E3S99_RS10305	COG1309	transcriptional regulator
E3S99_RS10335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S99_RS10360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S99_RS10370	COG0201	protein transport
E3S99_RS10380	COG1073	alpha beta
E3S99_RS10395	COG0438	transferase activity, transferring glycosyl groups
E3S99_RS10410	COG1535	isochorismatase
E3S99_RS10410	COG3433	isochorismatase activity
E3S99_RS10415	COG3942	CHAP domain
E3S99_RS10415	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3S99_RS10425	COG1482	cell wall glycoprotein biosynthetic process
E3S99_RS10430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S99_RS10430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S99_RS10430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S99_RS10435	COG3711	transcriptional antiterminator
E3S99_RS10435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S99_RS10455	COG1438	arginine binding
E3S99_RS10465	COG2235	arginine
E3S99_RS10490	COG4932	domain protein
E3S99_RS10490	COG4932	domain protein
E3S99_RS10490	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E3S99_RS10490	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E3S99_RS10500	COG1846	Transcriptional regulator
E3S99_RS10510	COG1785	Belongs to the alkaline phosphatase family
E3S99_RS10520	COG0745	RESPONSE REGULATOR receiver
E3S99_RS10525	COG2205	protein histidine kinase activity
E3S99_RS10530	COG1136	(ABC) transporter
E3S99_RS10550	COG0386	Belongs to the glutathione peroxidase family
E3S99_RS10560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3S99_RS10575	COG2851	Citrate transporter
E3S99_RS10600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S99_RS10605	COG1510	regulation of RNA biosynthetic process
E3S99_RS10635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S99_RS10665	COG0531	amino acid
E3S99_RS10675	COG3527	Alpha-acetolactate decarboxylase
E3S99_RS10680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S99_RS10730	COG0167	dihydroorotate dehydrogenase activity
E3S99_RS10840	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
E3S99_RS10840	COG2755	lipolytic protein G-D-S-L family
E3S99_RS10875	COG0436	Aminotransferase
E3S99_RS10890	COG2217	Heavy metal translocating P-type atpase
E3S99_RS10920	COG2409	Drug exporters of the RND superfamily
E3S99_RS10945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3S99_RS10950	COG3425	synthase
E3S99_RS10960	COG3942	CHAP domain
E3S99_RS10970	COG0583	DNA-binding transcription factor activity
E3S99_RS10985	COG0028	Belongs to the TPP enzyme family
E3S99_RS11005	COG0657	acetylesterase activity
E3S99_RS11010	COG0697	spore germination
E3S99_RS11025	COG1760	l-serine dehydratase
E3S99_RS11030	COG1760	l-serine dehydratase
E3S99_RS11050	COG3764	Sortase (surface protein transpeptidase)
E3S99_RS11060	COG1131	(ABC) transporter
E3S99_RS11065	COG0561	phosphatase activity
E3S99_RS11080	COG2514	catechol 2,3-dioxygenase activity
E3S99_RS11090	COG1846	Transcriptional regulator
E3S99_RS11095	COG0346	lactoylglutathione lyase activity
E3S99_RS11100	COG0400	carboxylic ester hydrolase activity
E3S99_RS11120	COG1131	(ABC) transporter
E3S99_RS11130	COG0586	Pfam SNARE associated Golgi protein
E3S99_RS11135	COG2271	Major facilitator Superfamily
E3S99_RS11145	COG4876	unkown
E3S99_RS11150	COG2357	RelA SpoT domain protein
E3S99_RS11155	COG0789	Transcriptional regulator
E3S99_RS11160	COG1802	Transcriptional regulator
E3S99_RS11165	COG1070	Carbohydrate kinase
E3S99_RS11210	COG0494	nUDIX hydrolase
E3S99_RS11305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3S99_RS11310	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3S99_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
E3S99_RS11320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3S99_RS11340	COG0747	negative chemotaxis
E3S99_RS11345	COG0601	transmembrane transport
E3S99_RS11350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S99_RS11360	COG1124	(ABC) transporter
E3S99_RS11375	COG0069	glutamate synthase activity
E3S99_RS11380	COG4808	Protein conserved in bacteria
E3S99_RS11385	COG1363	Peptidase, m42
E3S99_RS11390	COG4619	ABC transporter
E3S99_RS11395	COG0390	transport system, permease component
E3S99_RS11400	COG2814	Major facilitator Superfamily
E3S99_RS11405	COG2272	Belongs to the type-B carboxylesterase lipase family
E3S99_RS11415	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E3S99_RS11435	COG1174	glycine betaine transport
E3S99_RS11445	COG1174	glycine betaine transport
E3S99_RS11455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S99_RS11470	COG0531	amino acid
E3S99_RS11480	COG1113	amino acid transport
E3S99_RS11500	COG2814	Major facilitator Superfamily
E3S99_RS11510	COG1929	Belongs to the glycerate kinase type-1 family
E3S99_RS11535	COG1132	(ABC) transporter
E3S99_RS11545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3S99_RS11550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3S99_RS11560	COG0156	8-amino-7-oxononanoate synthase activity
E3S99_RS11600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E3S99_RS11620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3S99_RS11625	COG0765	amino acid transport
E3S99_RS11630	COG1126	abc transporter atp-binding protein
E3S99_RS11650	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3S99_RS11650	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S99_RS11665	COG2116	formate transmembrane transporter activity
E3S99_RS11670	COG0454	-acetyltransferase
E3S99_RS11680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3S99_RS11685	COG2146	nitrite reductase [NAD(P)H] activity
E3S99_RS11695	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3S99_RS11700	COG1140	nitrate reductase beta subunit
E3S99_RS11710	COG2181	nitrate reductase activity
E3S99_RS11730	COG0789	Transcriptional regulator
E3S99_RS11770	COG3871	stress protein (general stress protein 26)
E3S99_RS11785	COG1263	PTS System
E3S99_RS11785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S99_RS11800	COG1511	domain protein
E3S99_RS11825	COG0604	alcohol dehydrogenase
E3S99_RS11845	COG1620	l-lactate permease
E3S99_RS11860	COG1131	(ABC) transporter
E3S99_RS11920	COG2814	Major facilitator Superfamily
E3S99_RS11930	COG1566	PFAM secretion protein HlyD family protein
E3S99_RS11935	COG2814	Major facilitator Superfamily
E3S99_RS11945	COG0657	acetylesterase activity
E3S99_RS11960	COG0598	Magnesium transport protein CorA
E3S99_RS11970	COG0786	glutamate:sodium symporter activity
E3S99_RS11980	COG3152	Membrane
E3S99_RS11985	COG4152	abc transporter atp-binding protein
E3S99_RS11990	COG1668	transmembrane transport
E3S99_RS12010	COG2258	MOSC domain
E3S99_RS12030	COG0583	DNA-binding transcription factor activity
E3S99_RS12045	COG1473	amidohydrolase
E3S99_RS12050	COG1028	Short-chain dehydrogenase reductase Sdr
E3S99_RS12070	COG1737	Transcriptional regulator
E3S99_RS12075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S99_RS12075	COG1263	PTS System
E3S99_RS12085	COG0385	Bile acid
E3S99_RS12090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3S99_RS12110	COG1113	amino acid transport
E3S99_RS12195	COG1757	Na H antiporter
E3S99_RS12265	COG4413	Urea transporter
E3S99_RS12270	COG1960	acyl-CoA dehydrogenase activity
E3S99_RS12285	COG1268	BioY protein
E3S99_RS12300	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3S99_RS12305	COG4149	molybdate abc transporter
E3S99_RS12310	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3S99_RS12315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3S99_RS12335	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3S99_RS12395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3S99_RS12440	COG2252	PERMEase
E3S99_RS12555	COG0201	protein transport
E3S99_RS12640	COG0028	Belongs to the TPP enzyme family
E3S99_RS12645	COG3527	Alpha-acetolactate decarboxylase
E3S99_RS12660	COG0438	transferase activity, transferring glycosyl groups
E3S99_RS12675	COG5492	domain, Protein
E3S99_RS12685	COG0789	Transcriptional regulator
E3S99_RS12690	COG0656	L-ascorbic acid biosynthetic process
E3S99_RS12750	COG2130	NADP-dependent
E3S99_RS12765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S99_RS12790	COG2814	Major facilitator Superfamily
E3S99_RS12795	COG4264	IucA IucC family
E3S99_RS12800	COG3457	Alanine racemase
E3S99_RS12810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S99_RS12815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S99_RS12820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S99_RS12835	COG1988	membrane-bound metal-dependent
E3S99_RS12845	COG1272	protein, Hemolysin III
E3S99_RS12860	COG2814	Major facilitator Superfamily
E3S99_RS12865	COG0489	protein tyrosine kinase activity
E3S99_RS12925	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E3S99_RS12955	COG3711	transcriptional antiterminator
E3S99_RS12970	COG1119	ATPase activity
E3S99_RS12975	COG0561	phosphatase activity
E3S99_RS12995	COG0640	Transcriptional regulator
E3S99_RS13000	COG0702	epimerase
E3S99_RS13005	COG1482	cell wall glycoprotein biosynthetic process
E3S99_RS13025	COG0783	Belongs to the Dps family
E3S99_RS13030	COG0813	purine-nucleoside phosphorylase activity
E3S99_RS13075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S99_RS13115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3S99_RS13135	COG2890	protein-(glutamine-N5) methyltransferase activity
E3S99_RS13140	COG0009	L-threonylcarbamoyladenylate synthase
E3S99_RS13165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S99_RS13240	COG0629	single-stranded DNA binding
E3S99_RS13275	COG1418	mRNA catabolic process
E3S99_RS13285	COG1937	Protein conserved in bacteria
E3S99_RS13300	COG0772	Belongs to the SEDS family
E3S99_RS13310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3S99_RS13320	COG0745	RESPONSE REGULATOR receiver
E3S99_RS13325	COG2205	protein histidine kinase activity
E3S99_RS13355	COG3428	Bacterial PH domain
E3S99_RS13385	COG2208	phosphoserine phosphatase activity
E3S99_RS13390	COG1366	Belongs to the anti-sigma-factor antagonist family
E3S99_RS13400	COG1191	sigma factor activity
E3S99_RS13405	COG2183	response to ionizing radiation
E3S99_RS13480	COG0028	Belongs to the TPP enzyme family
E3S99_RS13495	COG0802	atpase or kinase
E3S99_RS13500	COG1214	PFAM Peptidase M22, glycoprotease
E3S99_RS13505	COG0456	acetyltransferase
E3S99_RS13515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E3S99_RS13525	COG0488	(ABC) transporter
E3S99_RS13535	COG2391	methyltransferase activity
E3S99_RS13540	COG0425	Belongs to the sulfur carrier protein TusA family
E3S99_RS13545	COG0004	ammonium transporteR
E3S99_RS13550	COG1609	Transcriptional regulator
E3S99_RS13555	COG1621	beta-fructofuranosidase activity
E3S99_RS13560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3S99_RS13630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S99_RS13680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair