locus-tag	class	description
E3S68_RS00020	COG0740	serine-type endopeptidase activity
E3S68_RS00070	COG0739	heme binding
E3S68_RS00120	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S68_RS00120	COG1388	LysM domain
E3S68_RS00185	COG1725	Transcriptional regulator
E3S68_RS00200	COG1131	(ABC) transporter
E3S68_RS00255	COG1012	belongs to the aldehyde dehydrogenase family
E3S68_RS00270	COG1335	isochorismatase
E3S68_RS00280	COG0471	metal ion transport
E3S68_RS00290	COG0077	Prephenate dehydratase
E3S68_RS00300	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3S68_RS00335	COG4496	protein, YerC YecD
E3S68_RS00355	COG4851	CamS sex pheromone cAM373 precursor
E3S68_RS00470	COG1295	ribonuclease BN
E3S68_RS00490	COG2309	aminopeptidase activity
E3S68_RS00495	COG1607	acyl-coa hydrolase
E3S68_RS00500	COG0535	radical SAM domain protein
E3S68_RS00530	COG1388	LysM domain
E3S68_RS00530	COG1134	teichoic acid transport
E3S68_RS00540	COG1988	membrane-bound metal-dependent
E3S68_RS00565	COG4129	membrane
E3S68_RS00575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3S68_RS00580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S68_RS00755	COG0765	amino acid transport
E3S68_RS00760	COG1126	abc transporter atp-binding protein
E3S68_RS00765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3S68_RS00795	COG0564	pseudouridine synthase activity
E3S68_RS00800	COG2203	Gaf domain
E3S68_RS00800	COG4585	Histidine kinase
E3S68_RS00805	COG2197	response regulator
E3S68_RS00830	COG0420	3'-5' exonuclease activity
E3S68_RS00860	COG0537	adenosine 5'-monophosphoramidase activity
E3S68_RS00865	COG1131	(ABC) transporter
E3S68_RS01140	COG2816	NAD+ diphosphatase activity
E3S68_RS01145	COG1506	peptidase
E3S68_RS01165	COG0656	L-ascorbic acid biosynthetic process
E3S68_RS01180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E3S68_RS01190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3S68_RS01220	COG3266	domain, Protein
E3S68_RS01220	COG4193	domain, Protein
E3S68_RS01220	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S68_RS01240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S68_RS01240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S68_RS01270	COG2267	carboxylic ester hydrolase activity
E3S68_RS01275	COG1846	Transcriptional regulator
E3S68_RS01280	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3S68_RS01285	COG1242	4 iron, 4 sulfur cluster binding
E3S68_RS01290	COG2814	Major facilitator Superfamily
E3S68_RS01310	COG2081	HI0933 family
E3S68_RS01315	COG2244	polysaccharide biosynthetic process
E3S68_RS01320	COG1187	pseudouridine synthase activity
E3S68_RS01340	COG0510	thiamine kinase activity
E3S68_RS01350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S68_RS01360	COG1363	Peptidase, m42
E3S68_RS01365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S68_RS01375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3S68_RS01380	COG1674	ftsk spoiiie
E3S68_RS01405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E3S68_RS01405	COG1605	Chorismate mutase
E3S68_RS01425	COG0454	-acetyltransferase
E3S68_RS01430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S68_RS01465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3S68_RS01470	COG0204	Acyl-transferase
E3S68_RS01475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S68_RS01475	COG1263	PTS System
E3S68_RS01490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S68_RS01495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E3S68_RS01500	COG1764	response to oxidative stress
E3S68_RS01505	COG0584	glycerophosphoryl diester phosphodiesterase
E3S68_RS01520	COG1956	GAF domain-containing protein
E3S68_RS01535	COG1104	cysteine desulfurase activity
E3S68_RS01545	COG0730	response to heat
E3S68_RS01555	COG0827	DNA restriction-modification system
E3S68_RS01595	COG4109	DRTGG domain
E3S68_RS01600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3S68_RS01610	COG0281	malic enzyme
E3S68_RS01635	COG1113	amino acid transport
E3S68_RS01640	COG0372	Belongs to the citrate synthase family
E3S68_RS01650	COG0745	RESPONSE REGULATOR receiver
E3S68_RS01655	COG5002	protein histidine kinase activity
E3S68_RS01665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S68_RS01665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S68_RS01670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3S68_RS01695	COG1484	DNA-dependent DNA replication
E3S68_RS01710	COG0833	amino acid
E3S68_RS01730	COG4112	unkown
E3S68_RS01765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3S68_RS01780	COG0113	porphobilinogen synthase activity
E3S68_RS01800	COG2818	Glycosylase
E3S68_RS01810	COG0285	dihydrofolate synthase activity
E3S68_RS01815	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E3S68_RS01855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3S68_RS01900	COG2868	ribosomal protein
E3S68_RS01940	COG1862	Preprotein translocase
E3S68_RS01945	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S68_RS01945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S68_RS01950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3S68_RS01950	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E3S68_RS01995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3S68_RS02000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3S68_RS02005	COG1959	2 iron, 2 sulfur cluster binding
E3S68_RS02020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S68_RS02025	COG1104	cysteine desulfurase activity
E3S68_RS02040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3S68_RS02090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3S68_RS02095	COG1984	allophanate hydrolase subunit 2
E3S68_RS02100	COG0511	ligase activity, forming carbon-carbon bonds
E3S68_RS02105	COG0439	Biotin carboxylase
E3S68_RS02115	COG1914	H( )-stimulated, divalent metal cation uptake system
E3S68_RS02120	COG3177	Filamentation induced by cAMP protein fic
E3S68_RS02140	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E3S68_RS02145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E3S68_RS02155	COG1534	Rna-binding protein
E3S68_RS02165	COG1713	HD superfamily hydrolase involved in NAD metabolism
E3S68_RS02170	COG0799	negative regulation of ribosome biogenesis
E3S68_RS02175	COG2226	methyltransferase
E3S68_RS02180	COG2183	response to ionizing radiation
E3S68_RS02185	COG2131	deaminase
E3S68_RS02190	COG0658	competence protein
E3S68_RS02190	COG2333	competence protein COMEC
E3S68_RS02195	COG1466	dna polymerase III delta subunit
E3S68_RS02210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3S68_RS02240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3S68_RS02245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3S68_RS02255	COG1030	water channel activity
E3S68_RS02270	COG1702	phosphate starvation-inducible protein PhoH
E3S68_RS02285	COG0295	cytidine deaminase activity
E3S68_RS02305	COG0517	IMP dehydrogenase activity
E3S68_RS02320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3S68_RS02325	COG2384	SAM-dependent methyltransferase
E3S68_RS02335	COG0513	Belongs to the DEAD box helicase family
E3S68_RS02345	COG1121	(ABC) transporter
E3S68_RS02350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S68_RS02355	COG0735	belongs to the Fur family
E3S68_RS02375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3S68_RS02385	COG4483	Protein conserved in bacteria
E3S68_RS02390	COG1940	carbohydrate kinase activity
E3S68_RS02395	COG0011	TIGRFAM Protein of
E3S68_RS02400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S68_RS02405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3S68_RS02410	COG1459	type II secretion system
E3S68_RS02415	COG4537	Required for transformation and DNA binding
E3S68_RS02460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3S68_RS02465	COG0095	Lipoate-protein ligase
E3S68_RS02480	COG0006	proline dipeptidase activity
E3S68_RS02490	COG0511	ligase activity, forming carbon-carbon bonds
E3S68_RS02495	COG0439	Biotin carboxylase
E3S68_RS02500	COG1302	Protein conserved in bacteria
E3S68_RS02530	COG0497	DNA recombination
E3S68_RS02535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S68_RS02540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E3S68_RS02545	COG0022	dehydrogenase e1 component
E3S68_RS02550	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3S68_RS02560	COG4129	membrane
E3S68_RS02570	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3S68_RS02595	COG1609	Transcriptional regulator
E3S68_RS02600	COG0366	Alpha amylase catalytic
E3S68_RS02610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3S68_RS02625	COG4221	oxidoreductase activity
E3S68_RS02635	COG0667	Aldo Keto reductase
E3S68_RS02640	COG0494	nUDIX hydrolase
E3S68_RS02645	COG0735	belongs to the Fur family
E3S68_RS02670	COG1187	pseudouridine synthase activity
E3S68_RS02675	COG0745	RESPONSE REGULATOR receiver
E3S68_RS02720	COG1141	Ferredoxin
E3S68_RS02730	COG0514	ATP-dependent DNA helicase (RecQ)
E3S68_RS02745	COG0492	ferredoxin-NADP+ reductase activity
E3S68_RS02800	COG0142	geranyltranstransferase activity
E3S68_RS02840	COG4347	Protein of unknown function (DUF1405)
E3S68_RS02845	COG2738	Putative neutral zinc metallopeptidase
E3S68_RS02850	COG1694	Mazg nucleotide pyrophosphohydrolase
E3S68_RS02855	COG0438	transferase activity, transferring glycosyl groups
E3S68_RS02880	COG3935	DnaD domain protein
E3S68_RS02885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3S68_RS02895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3S68_RS02895	COG4499	WXG100 protein secretion system (Wss), protein YukC
E3S68_RS02930	COG0116	Belongs to the methyltransferase superfamily
E3S68_RS02945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3S68_RS02950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S68_RS02965	COG0531	amino acid
E3S68_RS02985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3S68_RS03060	COG0671	phosphoesterase, PA-phosphatase related
E3S68_RS03110	COG4548	von Willebrand factor, type A
E3S68_RS03180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3S68_RS03185	COG0527	aspartate kinase activity
E3S68_RS03190	COG0488	(ABC) transporter
E3S68_RS03210	COG0573	inorganic phosphate transmembrane transporter activity
E3S68_RS03215	COG0581	inorganic phosphate transmembrane transporter activity
E3S68_RS03225	COG0704	Plays a role in the regulation of phosphate uptake
E3S68_RS03280	COG2348	transferase activity, transferring amino-acyl groups
E3S68_RS03315	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S68_RS03320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S68_RS03325	COG1363	Peptidase, m42
E3S68_RS03335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3S68_RS03345	COG1316	TRANSCRIPTIONal
E3S68_RS03350	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S68_RS03360	COG0628	permease
E3S68_RS03375	COG1115	amino acid carrier protein
E3S68_RS03400	COG0824	Thioesterase
E3S68_RS03410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S68_RS03430	COG4846	Membrane protein involved in cytochrome C biogenesis
E3S68_RS03465	COG2340	Cysteine-rich secretory protein family
E3S68_RS03495	COG0833	amino acid
E3S68_RS03520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3S68_RS03525	COG0460	homoserine dehydrogenase
E3S68_RS03530	COG0527	aspartate kinase activity
E3S68_RS03545	COG1525	nuclease
E3S68_RS03555	COG2197	response regulator
E3S68_RS03570	COG1131	(ABC) transporter
E3S68_RS03650	COG0789	Transcriptional regulator
E3S68_RS03655	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E3S68_RS03660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E3S68_RS03670	COG1923	regulation of RNA biosynthetic process
E3S68_RS03695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3S68_RS03700	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3S68_RS03735	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3S68_RS03740	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3S68_RS03740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3S68_RS03745	COG1692	metallophosphoesterase
E3S68_RS03765	COG1058	Belongs to the CinA family
E3S68_RS03765	COG1546	Belongs to the CinA family
E3S68_RS03785	COG0300	oxidoreductase activity
E3S68_RS03790	COG0612	Peptidase, M16
E3S68_RS03795	COG0612	Peptidase, M16
E3S68_RS03800	COG2188	Transcriptional regulator
E3S68_RS03825	COG0196	riboflavin kinase activity
E3S68_RS03850	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E3S68_RS03855	COG0195	Participates in both transcription termination and antitermination
E3S68_RS03955	COG2348	transferase activity, transferring amino-acyl groups
E3S68_RS04010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3S68_RS04020	COG0552	protein localization to endoplasmic reticulum
E3S68_RS04025	COG1196	nuclear chromosome segregation
E3S68_RS04070	COG1302	Protein conserved in bacteria
E3S68_RS04085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3S68_RS04100	COG0631	protein serine/threonine phosphatase activity
E3S68_RS04110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3S68_RS04110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3S68_RS04125	COG2314	TM2 domain
E3S68_RS04135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3S68_RS04140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3S68_RS04200	COG2233	PERMEase
E3S68_RS04210	COG0564	pseudouridine synthase activity
E3S68_RS04225	COG2514	catechol 2,3-dioxygenase activity
E3S68_RS04235	COG3599	regulation of cell shape
E3S68_RS04240	COG2302	S4 RNA-binding domain
E3S68_RS04245	COG0762	integral membrane protein
E3S68_RS04255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3S68_RS04265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3S68_RS04270	COG0849	cell division
E3S68_RS04275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E3S68_RS04295	COG4839	cell division protein FtsL
E3S68_RS04320	COG1011	Hydrolase
E3S68_RS04355	COG1288	antiporter activity
E3S68_RS04465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3S68_RS04470	COG1053	succinate dehydrogenase
E3S68_RS04475	COG2009	succinate dehydrogenase
E3S68_RS04500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3S68_RS04500	COG1796	DNA polymerase
E3S68_RS04530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3S68_RS04545	COG4509	Sortase family
E3S68_RS04600	COG0742	ribosomal rna small subunit methyltransferase
E3S68_RS04620	COG3679	Belongs to the UPF0342 family
E3S68_RS04645	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3S68_RS04650	COG0772	Belongs to the SEDS family
E3S68_RS04660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E3S68_RS04680	COG0483	inositol monophosphate 1-phosphatase activity
E3S68_RS04705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3S68_RS04710	COG1177	transmembrane transport
E3S68_RS04715	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3S68_RS04780	COG0569	domain protein
E3S68_RS04785	COG1294	oxidase, subunit
E3S68_RS04790	COG1271	oxidase subunit
E3S68_RS04795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3S68_RS04815	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3S68_RS04835	COG4721	ABC-type cobalt transport system, permease component
E3S68_RS04840	COG4172	Belongs to the ABC transporter superfamily
E3S68_RS04845	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E3S68_RS04885	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3S68_RS04900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3S68_RS04945	COG1316	TRANSCRIPTIONal
E3S68_RS04955	COG2153	protein acetylation
E3S68_RS04975	COG3594	Acyltransferase
E3S68_RS04980	COG0436	Aminotransferase
E3S68_RS05005	COG2267	carboxylic ester hydrolase activity
E3S68_RS05015	COG1169	isochorismate synthase
E3S68_RS05025	COG1575	Belongs to the MenA family. Type 1 subfamily
E3S68_RS05030	COG0456	acetyltransferase
E3S68_RS05035	COG2314	TM2 domain
E3S68_RS05045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S68_RS05100	COG4873	Protein conserved in bacteria
E3S68_RS05115	COG4903	ComK protein
E3S68_RS05135	COG0737	Belongs to the 5'-nucleotidase family
E3S68_RS05140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S68_RS05150	COG0861	Integral membrane protein TerC family
E3S68_RS05190	COG1115	amino acid carrier protein
E3S68_RS05195	COG0628	permease
E3S68_RS05205	COG0475	glutathione-regulated potassium exporter activity
E3S68_RS05205	COG0569	domain protein
E3S68_RS05210	COG2239	Acts as a magnesium transporter
E3S68_RS05215	COG0564	pseudouridine synthase activity
E3S68_RS05225	COG2357	RelA SpoT domain protein
E3S68_RS05240	COG2346	COG2346, Truncated hemoglobins
E3S68_RS05250	COG1164	Oligoendopeptidase f
E3S68_RS05275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S68_RS05280	COG0601	transmembrane transport
E3S68_RS05285	COG4608	Belongs to the ABC transporter superfamily
E3S68_RS05290	COG0444	Belongs to the ABC transporter superfamily
E3S68_RS05295	COG0747	negative chemotaxis
E3S68_RS05300	COG4166	transmembrane transport
E3S68_RS05305	COG4608	Belongs to the ABC transporter superfamily
E3S68_RS05310	COG0444	Belongs to the ABC transporter superfamily
E3S68_RS05315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S68_RS05320	COG0601	transmembrane transport
E3S68_RS05350	COG1881	PFAM PEBP family protein
E3S68_RS05390	COG0561	phosphatase activity
E3S68_RS05430	COG0398	Pfam SNARE associated Golgi protein
E3S68_RS05450	COG0584	glycerophosphoryl diester phosphodiesterase
E3S68_RS05465	COG1902	pentaerythritol trinitrate reductase activity
E3S68_RS05470	COG1098	S1 RNA binding domain
E3S68_RS05525	COG2050	protein possibly involved in aromatic compounds catabolism
E3S68_RS05530	COG2056	Na+-H+ antiporter family
E3S68_RS05535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3S68_RS05545	COG0316	Belongs to the HesB IscA family
E3S68_RS05555	COG1252	NADH dehydrogenase
E3S68_RS05560	COG4837	Protein of unknown function (DUF1462)
E3S68_RS05565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3S68_RS05570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E3S68_RS05580	COG1696	Membrane protein involved in D-alanine export
E3S68_RS05610	COG2445	Protein of unknown function DUF86
E3S68_RS05625	COG4470	Protein conserved in bacteria
E3S68_RS05640	COG0730	response to heat
E3S68_RS05645	COG1801	Protein of unknown function DUF72
E3S68_RS05660	COG1253	flavin adenine dinucleotide binding
E3S68_RS05680	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S68_RS05680	COG1388	LysM domain
E3S68_RS05810	COG1783	phage Terminase large subunit
E3S68_RS05910	COG1484	DNA-dependent DNA replication
E3S68_RS06015	COG0822	iron-sulfur transferase activity
E3S68_RS06025	COG0719	Fe-S assembly protein
E3S68_RS06030	COG0396	ATPase activity
E3S68_RS06045	COG1464	Belongs to the NlpA lipoprotein family
E3S68_RS06050	COG2011	ABC-type metal ion transport system permease component
E3S68_RS06065	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S68_RS06070	COG3878	Protein conserved in bacteria
E3S68_RS06085	COG1393	Belongs to the ArsC family
E3S68_RS06090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S68_RS06115	COG1279	arginine transmembrane transporter activity
E3S68_RS06120	COG0406	alpha-ribazole phosphatase activity
E3S68_RS06160	COG1278	Cold shock
E3S68_RS06230	COG0557	exoribonuclease II activity
E3S68_RS06235	COG1647	Serine aminopeptidase, S33
E3S68_RS06240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S68_RS06300	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3S68_RS06355	COG1388	LysM domain
E3S68_RS06355	COG3942	CHAP domain
E3S68_RS06390	COG1040	competence protein
E3S68_RS06395	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E3S68_RS06405	COG1739	Uncharacterized protein family UPF0029
E3S68_RS06410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3S68_RS06470	COG4607	ABC-type enterochelin transport system periplasmic component
E3S68_RS06475	COG4604	ABC transporter, ATP-binding protein
E3S68_RS06480	COG4605	iron ion homeostasis
E3S68_RS06485	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S68_RS06495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S68_RS06500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S68_RS06520	COG3104	oligopeptide transport
E3S68_RS06545	COG1174	glycine betaine transport
E3S68_RS06550	COG1125	glycine betaine transport
E3S68_RS06550	COG0517	IMP dehydrogenase activity
E3S68_RS06555	COG0514	ATP-dependent DNA helicase (RecQ)
E3S68_RS06560	COG0488	(ABC) transporter
E3S68_RS06590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S68_RS06595	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S68_RS06595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3S68_RS06605	COG0720	synthase
E3S68_RS06640	COG0463	Glycosyl transferase, family 2
E3S68_RS06645	COG0656	L-ascorbic acid biosynthetic process
E3S68_RS06650	COG1253	flavin adenine dinucleotide binding
E3S68_RS06655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3S68_RS06660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S68_RS06660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S68_RS06660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S68_RS06665	COG1105	Belongs to the carbohydrate kinase PfkB family
E3S68_RS06670	COG1349	DNA-binding transcription factor activity
E3S68_RS06675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3S68_RS06710	COG0471	metal ion transport
E3S68_RS06720	COG4989	oxidoreductase activity
E3S68_RS06725	COG0523	cobalamin synthesis protein
E3S68_RS06730	COG1846	Transcriptional regulator
E3S68_RS06735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3S68_RS06740	COG4988	ABC transporter
E3S68_RS06760	COG1611	Belongs to the LOG family
E3S68_RS06790	COG2839	Protein conserved in bacteria
E3S68_RS06795	COG2814	Major facilitator Superfamily
E3S68_RS06800	COG0583	DNA-binding transcription factor activity
E3S68_RS06830	COG1917	Cupin 2, conserved barrel domain protein
E3S68_RS06830	COG4977	sequence-specific DNA binding
E3S68_RS06840	COG1388	LysM domain
E3S68_RS06840	COG3942	CHAP domain
E3S68_RS06845	COG0306	phosphate transporter
E3S68_RS06850	COG1392	Phosphate transport regulator
E3S68_RS06855	COG0577	efflux transmembrane transporter activity
E3S68_RS06860	COG1136	(ABC) transporter
E3S68_RS06895	COG3949	Membrane
E3S68_RS06905	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E3S68_RS06915	COG2376	Dihydroxyacetone kinase
E3S68_RS06920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S68_RS06925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S68_RS06930	COG1120	ATPase activity
E3S68_RS06935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E3S68_RS06945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S68_RS06950	COG1132	(ABC) transporter
E3S68_RS06955	COG1686	Belongs to the peptidase S11 family
E3S68_RS06960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3S68_RS06970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S68_RS06975	COG1682	transport, permease protein
E3S68_RS06985	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
E3S68_RS06995	COG1321	iron dependent repressor
E3S68_RS07000	COG1121	(ABC) transporter
E3S68_RS07005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S68_RS07010	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S68_RS07060	COG4974	Belongs to the 'phage' integrase family
E3S68_RS07115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S68_RS07150	COG1078	dGTPase activity
E3S68_RS07160	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S68_RS07165	COG0667	Aldo Keto reductase
E3S68_RS07200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S68_RS07220	COG0083	homoserine kinase activity
E3S68_RS07225	COG0095	Lipoate-protein ligase
E3S68_RS07315	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E3S68_RS07330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3S68_RS07370	COG0561	phosphatase activity
E3S68_RS07380	COG1428	Deoxynucleoside kinase
E3S68_RS07385	COG1428	Deoxynucleoside kinase
E3S68_RS07390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3S68_RS07420	COG1473	amidohydrolase
E3S68_RS07450	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E3S68_RS07460	COG2813	Specifically methylates the guanine in position
E3S68_RS07490	COG0250	Participates in transcription elongation, termination and antitermination
E3S68_RS07495	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S68_RS07520	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3S68_RS07540	COG4956	integral membrane protein (PIN domain superfamily)
E3S68_RS07545	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3S68_RS07560	COG3880	PFAM UvrB UvrC protein
E3S68_RS07570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S68_RS07585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S68_RS07665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3S68_RS07690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3S68_RS07705	COG1098	S1 RNA binding domain
E3S68_RS07715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3S68_RS07720	COG3956	TIGRFAM MazG family protein
E3S68_RS07725	COG2244	polysaccharide biosynthetic process
E3S68_RS07765	COG0251	oxidation-reduction process
E3S68_RS07770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3S68_RS07780	COG4466	Protein conserved in bacteria
E3S68_RS07790	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S68_RS07795	COG0084	hydrolase, TatD family'
E3S68_RS07805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3S68_RS07815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3S68_RS07825	COG1774	PSP1 C-terminal conserved region
E3S68_RS07830	COG0470	DNA polymerase III
E3S68_RS07835	COG3870	Protein conserved in bacteria
E3S68_RS07845	COG1982	Orn Lys Arg decarboxylase major
E3S68_RS07875	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E3S68_RS07880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3S68_RS07900	COG2188	Transcriptional regulator
E3S68_RS07905	COG0366	Alpha amylase catalytic
E3S68_RS07910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S68_RS07910	COG1263	PTS System
E3S68_RS07920	COG0493	'glutamate synthase
E3S68_RS07925	COG0067	glutamate synthase
E3S68_RS07925	COG0069	glutamate synthase activity
E3S68_RS07925	COG0070	glutamate synthase
E3S68_RS07930	COG0583	DNA-binding transcription factor activity
E3S68_RS07965	COG1464	Belongs to the NlpA lipoprotein family
E3S68_RS07970	COG2011	ABC-type metal ion transport system permease component
E3S68_RS07980	COG0626	cystathionine gamma-synthase activity
E3S68_RS07985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3S68_RS07990	COG0733	neurotransmitter:sodium symporter activity
E3S68_RS07995	COG1647	Serine aminopeptidase, S33
E3S68_RS08010	COG5609	conserved protein (DUF2294)
E3S68_RS08020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3S68_RS08045	COG0523	cobalamin synthesis protein
E3S68_RS08205	COG3759	membrane
E3S68_RS08240	COG2233	PERMEase
E3S68_RS08270	COG1823	symporter activity
E3S68_RS08370	COG0012	GTP binding
E3S68_RS08375	COG4481	Protein conserved in bacteria
E3S68_RS08380	COG0668	transmembrane transport
E3S68_RS08385	COG1475	DNA binding
E3S68_RS08390	COG0626	cystathionine gamma-synthase activity
E3S68_RS08395	COG0626	cystathionine gamma-synthase activity
E3S68_RS08400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3S68_RS08400	COG0646	methionine synthase
E3S68_RS08430	COG1131	(ABC) transporter
E3S68_RS08440	COG1476	TRANSCRIPTIONal
E3S68_RS08450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3S68_RS08455	COG0805	protein transport
E3S68_RS08460	COG0672	)-iron permease
E3S68_RS08465	COG2837	iron assimilation
E3S68_RS08470	COG2822	iron ion transport
E3S68_RS08475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S68_RS08485	COG0431	NADPH-dependent FMN reductase
E3S68_RS08490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S68_RS08495	COG0346	lactoylglutathione lyase activity
E3S68_RS08500	COG2271	Major facilitator Superfamily
E3S68_RS08525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S68_RS08535	COG3037	sugar-specific permease SgaT UlaA
E3S68_RS08565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S68_RS08585	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
E3S68_RS08585	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3S68_RS08600	COG1388	LysM domain
E3S68_RS08600	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S68_RS08650	COG5412	phage tail tape measure protein
E3S68_RS08650	COG3953	SLT domain
E3S68_RS08910	COG0582	viral genome integration into host DNA
E3S68_RS08945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3S68_RS08950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S68_RS08980	COG0577	efflux transmembrane transporter activity
E3S68_RS08985	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E3S68_RS08990	COG1114	Component of the transport system for branched-chain amino acids
E3S68_RS09110	COG3942	CHAP domain
E3S68_RS09110	COG1388	LysM domain
E3S68_RS09185	COG2226	methyltransferase
E3S68_RS09190	COG2723	6-phospho-beta-galactosidase activity
E3S68_RS09195	COG2190	(PTS) system
E3S68_RS09195	COG1263	PTS System
E3S68_RS09195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S68_RS09200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S68_RS09235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S68_RS09240	COG1063	alcohol dehydrogenase
E3S68_RS09250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S68_RS09255	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S68_RS09260	COG1063	alcohol dehydrogenase
E3S68_RS09265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E3S68_RS09270	COG1063	alcohol dehydrogenase
E3S68_RS09280	COG1063	alcohol dehydrogenase
E3S68_RS09285	COG3775	system Galactitol-specific IIC component
E3S68_RS09290	COG3414	Phosphotransferase system galactitol-specific IIB component
E3S68_RS09310	COG1957	nucleoside hydrolase
E3S68_RS09315	COG1263	PTS System
E3S68_RS09315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S68_RS09315	COG2190	(PTS) system
E3S68_RS09340	COG3189	MarR family transcriptional regulator
E3S68_RS09345	COG0747	negative chemotaxis
E3S68_RS09360	COG0318	PFAM AMP-dependent synthetase and ligase
E3S68_RS09365	COG1960	acyl-CoA dehydrogenase activity
E3S68_RS09375	COG0183	Belongs to the thiolase family
E3S68_RS09430	COG1755	Isoprenylcysteine carboxyl methyltransferase
E3S68_RS09440	COG0673	inositol 2-dehydrogenase activity
E3S68_RS09445	COG0673	inositol 2-dehydrogenase activity
E3S68_RS09450	COG3833	ABC-type maltose transport systems, permease component
E3S68_RS09455	COG1175	transmembrane transport
E3S68_RS09465	COG3842	ATPase activity
E3S68_RS09485	COG0405	Gamma-glutamyltransferase
E3S68_RS09495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S68_RS09540	COG1136	(ABC) transporter
E3S68_RS09565	COG1737	Transcriptional regulator
E3S68_RS09595	COG3961	Belongs to the TPP enzyme family
E3S68_RS09600	COG1335	isochorismatase
E3S68_RS09605	COG1114	Component of the transport system for branched-chain amino acids
E3S68_RS09655	COG5609	conserved protein (DUF2294)
E3S68_RS09660	COG1960	acyl-CoA dehydrogenase activity
E3S68_RS09665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3S68_RS09700	COG2832	Protein of unknown function (DUF454)
E3S68_RS09710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S68_RS09715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3S68_RS09725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S68_RS09755	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S68_RS09765	COG1086	Polysaccharide biosynthesis protein
E3S68_RS09790	COG1454	alcohol dehydrogenase
E3S68_RS09790	COG1012	belongs to the aldehyde dehydrogenase family
E3S68_RS09805	COG0737	Belongs to the 5'-nucleotidase family
E3S68_RS09825	COG3639	organic phosphonate transmembrane transporter activity
E3S68_RS09845	COG2814	Major facilitator Superfamily
E3S68_RS09850	COG0813	purine-nucleoside phosphorylase activity
E3S68_RS09880	COG0438	transferase activity, transferring glycosyl groups
E3S68_RS09885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S68_RS09890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3S68_RS09910	COG1475	DNA binding
E3S68_RS09915	COG0019	diaminopimelate decarboxylase activity
E3S68_RS09925	COG4264	IucA IucC family
E3S68_RS09930	COG4264	IucA IucC family
E3S68_RS09935	COG2814	Major facilitator Superfamily
E3S68_RS09940	COG4264	IucA IucC family
E3S68_RS09945	COG2423	ornithine cyclodeaminase activity
E3S68_RS09955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S68_RS09960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S68_RS09965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S68_RS09980	COG1620	l-lactate permease
E3S68_RS09995	COG0697	spore germination
E3S68_RS10000	COG4716	Myosin-crossreactive antigen
E3S68_RS10005	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3S68_RS10015	COG1473	amidohydrolase
E3S68_RS10050	COG0823	Involved in the tonB-independent uptake of proteins
E3S68_RS10095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S68_RS10100	COG2210	Belongs to the sulfur carrier protein TusA family
E3S68_RS10105	COG1937	Protein conserved in bacteria
E3S68_RS10110	COG0730	response to heat
E3S68_RS10180	COG2205	protein histidine kinase activity
E3S68_RS10185	COG0745	RESPONSE REGULATOR receiver
E3S68_RS10240	COG2003	Belongs to the UPF0758 family
E3S68_RS10275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3S68_RS10285	COG0730	response to heat
E3S68_RS10290	COG1937	Protein conserved in bacteria
E3S68_RS10295	COG2210	Belongs to the sulfur carrier protein TusA family
E3S68_RS10300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S68_RS10310	COG1940	carbohydrate kinase activity
E3S68_RS10310	COG1846	Transcriptional regulator
E3S68_RS10325	COG2602	Beta-lactamase
E3S68_RS10325	COG4219	Peptidase M56
E3S68_RS10335	COG2030	dehydratase
E3S68_RS10340	COG0584	glycerophosphoryl diester phosphodiesterase
E3S68_RS10345	COG3316	Transposase and inactivated derivatives
E3S68_RS10365	COG0737	Belongs to the 5'-nucleotidase family
E3S68_RS10370	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3S68_RS10380	COG4863	YycH protein
E3S68_RS10410	COG0305	Participates in initiation and elongation during chromosome replication
E3S68_RS10420	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E3S68_RS10430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3S68_RS10455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3S68_RS10475	COG2501	S4 domain
E3S68_RS10515	COG1475	DNA binding
E3S68_RS10535	COG1278	Cold shock
E3S68_RS10545	COG0577	efflux transmembrane transporter activity
E3S68_RS10550	COG1136	(ABC) transporter
E3S68_RS10565	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3S68_RS10575	COG2962	Rard protein
E3S68_RS10580	COG0471	metal ion transport
E3S68_RS10665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3S68_RS10705	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
E3S68_RS10720	COG1215	transferase activity, transferring glycosyl groups
E3S68_RS10725	COG1309	transcriptional regulator
E3S68_RS10755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S68_RS10775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S68_RS10795	COG1073	alpha beta
E3S68_RS10810	COG0438	transferase activity, transferring glycosyl groups
E3S68_RS10825	COG1535	isochorismatase
E3S68_RS10825	COG3433	isochorismatase activity
E3S68_RS10830	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3S68_RS10830	COG3942	CHAP domain
E3S68_RS10840	COG1482	cell wall glycoprotein biosynthetic process
E3S68_RS10845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S68_RS10845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S68_RS10845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S68_RS10850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S68_RS10850	COG3711	transcriptional antiterminator
E3S68_RS10905	COG4932	domain protein
E3S68_RS10905	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E3S68_RS10915	COG1846	Transcriptional regulator
E3S68_RS10925	COG1785	Belongs to the alkaline phosphatase family
E3S68_RS10935	COG0745	RESPONSE REGULATOR receiver
E3S68_RS10940	COG2205	protein histidine kinase activity
E3S68_RS10945	COG1136	(ABC) transporter
E3S68_RS10965	COG0386	Belongs to the glutathione peroxidase family
E3S68_RS10975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3S68_RS10990	COG2851	Citrate transporter
E3S68_RS11015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S68_RS11020	COG1510	regulation of RNA biosynthetic process
E3S68_RS11050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S68_RS11085	COG0531	amino acid
E3S68_RS11095	COG3527	Alpha-acetolactate decarboxylase
E3S68_RS11100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S68_RS11160	COG0167	dihydroorotate dehydrogenase activity
E3S68_RS11270	COG2755	lipolytic protein G-D-S-L family
E3S68_RS11270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
E3S68_RS11305	COG0436	Aminotransferase
E3S68_RS11350	COG2409	Drug exporters of the RND superfamily
E3S68_RS11375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3S68_RS11380	COG3425	synthase
E3S68_RS11390	COG3942	CHAP domain
E3S68_RS11400	COG0583	DNA-binding transcription factor activity
E3S68_RS11410	COG1346	cytolysis
E3S68_RS11415	COG0028	Belongs to the TPP enzyme family
E3S68_RS11435	COG0657	acetylesterase activity
E3S68_RS11440	COG0697	spore germination
E3S68_RS11455	COG1760	l-serine dehydratase
E3S68_RS11460	COG1760	l-serine dehydratase
E3S68_RS11480	COG3764	Sortase (surface protein transpeptidase)
E3S68_RS11490	COG1131	(ABC) transporter
E3S68_RS11495	COG0561	phosphatase activity
E3S68_RS11510	COG2514	catechol 2,3-dioxygenase activity
E3S68_RS11520	COG1846	Transcriptional regulator
E3S68_RS11525	COG0346	lactoylglutathione lyase activity
E3S68_RS11530	COG0400	carboxylic ester hydrolase activity
E3S68_RS11550	COG1131	(ABC) transporter
E3S68_RS11560	COG0586	Pfam SNARE associated Golgi protein
E3S68_RS11565	COG2271	Major facilitator Superfamily
E3S68_RS11575	COG4876	unkown
E3S68_RS11580	COG2357	RelA SpoT domain protein
E3S68_RS11585	COG0789	Transcriptional regulator
E3S68_RS11590	COG1802	Transcriptional regulator
E3S68_RS11595	COG1070	Carbohydrate kinase
E3S68_RS11630	COG1846	Transcriptional regulator
E3S68_RS11670	COG0494	nUDIX hydrolase
E3S68_RS11760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3S68_RS11765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3S68_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
E3S68_RS11775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3S68_RS11830	COG0069	glutamate synthase activity
E3S68_RS11835	COG4808	Protein conserved in bacteria
E3S68_RS11850	COG1363	Peptidase, m42
E3S68_RS11855	COG4619	ABC transporter
E3S68_RS11860	COG0390	transport system, permease component
E3S68_RS11865	COG2814	Major facilitator Superfamily
E3S68_RS11870	COG2272	Belongs to the type-B carboxylesterase lipase family
E3S68_RS11875	COG0531	amino acid
E3S68_RS11880	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E3S68_RS11900	COG1174	glycine betaine transport
E3S68_RS11910	COG1174	glycine betaine transport
E3S68_RS11920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S68_RS11935	COG0531	amino acid
E3S68_RS11945	COG1113	amino acid transport
E3S68_RS11965	COG2814	Major facilitator Superfamily
E3S68_RS11975	COG1929	Belongs to the glycerate kinase type-1 family
E3S68_RS11995	COG1132	(ABC) transporter
E3S68_RS12005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3S68_RS12010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3S68_RS12020	COG0156	8-amino-7-oxononanoate synthase activity
E3S68_RS12060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E3S68_RS12075	COG2814	Major facilitator Superfamily
E3S68_RS12080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3S68_RS12085	COG0765	amino acid transport
E3S68_RS12090	COG1126	abc transporter atp-binding protein
E3S68_RS12130	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S68_RS12130	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3S68_RS12145	COG2116	formate transmembrane transporter activity
E3S68_RS12150	COG0454	-acetyltransferase
E3S68_RS12160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3S68_RS12165	COG2146	nitrite reductase [NAD(P)H] activity
E3S68_RS12175	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3S68_RS12180	COG1140	nitrate reductase beta subunit
E3S68_RS12190	COG2181	nitrate reductase activity
E3S68_RS12210	COG0789	Transcriptional regulator
E3S68_RS12250	COG3871	stress protein (general stress protein 26)
E3S68_RS12265	COG1263	PTS System
E3S68_RS12265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S68_RS12280	COG1511	domain protein
E3S68_RS12305	COG0604	alcohol dehydrogenase
E3S68_RS12325	COG1620	l-lactate permease
E3S68_RS12385	COG2814	Major facilitator Superfamily
E3S68_RS12395	COG1566	PFAM secretion protein HlyD family protein
E3S68_RS12400	COG2814	Major facilitator Superfamily
E3S68_RS12410	COG0657	acetylesterase activity
E3S68_RS12425	COG0598	Magnesium transport protein CorA
E3S68_RS12435	COG0786	glutamate:sodium symporter activity
E3S68_RS12445	COG3152	Membrane
E3S68_RS12450	COG4152	abc transporter atp-binding protein
E3S68_RS12455	COG1668	transmembrane transport
E3S68_RS12475	COG2258	MOSC domain
E3S68_RS12500	COG0583	DNA-binding transcription factor activity
E3S68_RS12515	COG1473	amidohydrolase
E3S68_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
E3S68_RS12540	COG1737	Transcriptional regulator
E3S68_RS12545	COG1263	PTS System
E3S68_RS12545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S68_RS12555	COG0385	Bile acid
E3S68_RS12560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3S68_RS12580	COG1113	amino acid transport
E3S68_RS12660	COG1757	Na H antiporter
E3S68_RS12670	COG3942	CHAP domain
E3S68_RS12730	COG4413	Urea transporter
E3S68_RS12735	COG1960	acyl-CoA dehydrogenase activity
E3S68_RS12750	COG1268	BioY protein
E3S68_RS12765	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3S68_RS12770	COG4149	molybdate abc transporter
E3S68_RS12775	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3S68_RS12780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3S68_RS12800	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3S68_RS12860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3S68_RS12905	COG2252	PERMEase
E3S68_RS13020	COG0201	protein transport
E3S68_RS13125	COG0028	Belongs to the TPP enzyme family
E3S68_RS13130	COG3527	Alpha-acetolactate decarboxylase
E3S68_RS13150	COG5492	domain, Protein
E3S68_RS13160	COG0789	Transcriptional regulator
E3S68_RS13165	COG0656	L-ascorbic acid biosynthetic process
E3S68_RS13230	COG2130	NADP-dependent
E3S68_RS13240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S68_RS13265	COG2814	Major facilitator Superfamily
E3S68_RS13270	COG4264	IucA IucC family
E3S68_RS13275	COG3457	Alanine racemase
E3S68_RS13285	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S68_RS13290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S68_RS13295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S68_RS13310	COG1988	membrane-bound metal-dependent
E3S68_RS13320	COG1272	protein, Hemolysin III
E3S68_RS13335	COG2814	Major facilitator Superfamily
E3S68_RS13340	COG0489	protein tyrosine kinase activity
E3S68_RS13405	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E3S68_RS13435	COG3711	transcriptional antiterminator
E3S68_RS13450	COG1119	ATPase activity
E3S68_RS13455	COG0561	phosphatase activity
E3S68_RS13480	COG0640	Transcriptional regulator
E3S68_RS13485	COG0702	epimerase
E3S68_RS13490	COG1482	cell wall glycoprotein biosynthetic process
E3S68_RS13510	COG0783	Belongs to the Dps family
E3S68_RS13515	COG0813	purine-nucleoside phosphorylase activity
E3S68_RS13560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S68_RS13600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3S68_RS13620	COG2890	protein-(glutamine-N5) methyltransferase activity
E3S68_RS13625	COG0009	L-threonylcarbamoyladenylate synthase
E3S68_RS13650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S68_RS13725	COG0629	single-stranded DNA binding
E3S68_RS13775	COG1418	mRNA catabolic process
E3S68_RS13785	COG1937	Protein conserved in bacteria
E3S68_RS13800	COG0772	Belongs to the SEDS family
E3S68_RS13810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3S68_RS13825	COG0745	RESPONSE REGULATOR receiver
E3S68_RS13830	COG2205	protein histidine kinase activity
E3S68_RS13860	COG3428	Bacterial PH domain
E3S68_RS13890	COG2208	phosphoserine phosphatase activity
E3S68_RS13895	COG1366	Belongs to the anti-sigma-factor antagonist family
E3S68_RS13905	COG1191	sigma factor activity
E3S68_RS13910	COG2183	response to ionizing radiation
E3S68_RS13980	COG0028	Belongs to the TPP enzyme family
E3S68_RS13995	COG0802	atpase or kinase
E3S68_RS14000	COG1214	PFAM Peptidase M22, glycoprotease
E3S68_RS14005	COG0456	acetyltransferase
E3S68_RS14015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E3S68_RS14025	COG0488	(ABC) transporter
E3S68_RS14035	COG2391	methyltransferase activity
E3S68_RS14040	COG0425	Belongs to the sulfur carrier protein TusA family
E3S68_RS14045	COG0004	ammonium transporteR
E3S68_RS14050	COG1609	Transcriptional regulator
E3S68_RS14055	COG1621	beta-fructofuranosidase activity
E3S68_RS14060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3S68_RS14125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S68_RS14180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E3S68_RS14420	COG0604	alcohol dehydrogenase
