locus-tag	class	description
E3T13_RS00020	COG0740	serine-type endopeptidase activity
E3T13_RS00070	COG0739	heme binding
E3T13_RS00115	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3T13_RS00115	COG1388	LysM domain
E3T13_RS00125	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3T13_RS00125	COG1388	LysM domain
E3T13_RS00180	COG1725	Transcriptional regulator
E3T13_RS00195	COG1131	(ABC) transporter
E3T13_RS00245	COG1012	belongs to the aldehyde dehydrogenase family
E3T13_RS00260	COG1335	isochorismatase
E3T13_RS00280	COG0077	Prephenate dehydratase
E3T13_RS00290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3T13_RS00325	COG4496	protein, YerC YecD
E3T13_RS00345	COG4851	CamS sex pheromone cAM373 precursor
E3T13_RS00460	COG1295	ribonuclease BN
E3T13_RS00480	COG2309	aminopeptidase activity
E3T13_RS00485	COG1607	acyl-coa hydrolase
E3T13_RS00490	COG0535	radical SAM domain protein
E3T13_RS00495	COG4974	Belongs to the 'phage' integrase family
E3T13_RS00515	COG1396	sequence-specific DNA binding
E3T13_RS00655	COG1783	phage Terminase large subunit
E3T13_RS00785	COG1388	LysM domain
E3T13_RS00785	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3T13_RS00830	COG1388	LysM domain
E3T13_RS00830	COG1134	teichoic acid transport
E3T13_RS00840	COG1988	membrane-bound metal-dependent
E3T13_RS00845	COG1194	a g-specific adenine glycosylase
E3T13_RS00860	COG4129	membrane
E3T13_RS00870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3T13_RS00875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3T13_RS01030	COG0765	amino acid transport
E3T13_RS01035	COG1126	abc transporter atp-binding protein
E3T13_RS01040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3T13_RS01070	COG0564	pseudouridine synthase activity
E3T13_RS01075	COG2203	Gaf domain
E3T13_RS01075	COG4585	Histidine kinase
E3T13_RS01080	COG2197	response regulator
E3T13_RS01100	COG0420	3'-5' exonuclease activity
E3T13_RS01130	COG0537	adenosine 5'-monophosphoramidase activity
E3T13_RS01135	COG1131	(ABC) transporter
E3T13_RS01345	COG5492	domain, Protein
E3T13_RS01435	COG2816	NAD+ diphosphatase activity
E3T13_RS01440	COG1506	peptidase
E3T13_RS01460	COG0656	L-ascorbic acid biosynthetic process
E3T13_RS01470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E3T13_RS01480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3T13_RS01515	COG3266	domain, Protein
E3T13_RS01515	COG4193	domain, Protein
E3T13_RS01515	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3T13_RS01535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3T13_RS01535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3T13_RS01565	COG2267	carboxylic ester hydrolase activity
E3T13_RS01570	COG1846	Transcriptional regulator
E3T13_RS01575	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3T13_RS01580	COG1242	4 iron, 4 sulfur cluster binding
E3T13_RS01585	COG2814	Major facilitator Superfamily
E3T13_RS01605	COG2081	HI0933 family
E3T13_RS01610	COG2244	polysaccharide biosynthetic process
E3T13_RS01615	COG1187	pseudouridine synthase activity
E3T13_RS01635	COG0510	thiamine kinase activity
E3T13_RS01675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3T13_RS01685	COG1363	Peptidase, m42
E3T13_RS01690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3T13_RS01700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3T13_RS01705	COG1674	ftsk spoiiie
E3T13_RS01730	COG1605	Chorismate mutase
E3T13_RS01730	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E3T13_RS01750	COG0454	-acetyltransferase
E3T13_RS01755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3T13_RS01785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3T13_RS01790	COG0204	Acyl-transferase
E3T13_RS01795	COG1263	PTS System
E3T13_RS01795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3T13_RS01810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3T13_RS01815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E3T13_RS01820	COG1764	response to oxidative stress
E3T13_RS01825	COG0584	glycerophosphoryl diester phosphodiesterase
E3T13_RS01840	COG1956	GAF domain-containing protein
E3T13_RS01855	COG1104	cysteine desulfurase activity
E3T13_RS01865	COG0730	response to heat
E3T13_RS01875	COG0827	DNA restriction-modification system
E3T13_RS01915	COG4109	DRTGG domain
E3T13_RS01920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3T13_RS01930	COG0281	malic enzyme
E3T13_RS01955	COG1113	amino acid transport
E3T13_RS01960	COG0372	Belongs to the citrate synthase family
E3T13_RS01970	COG0745	RESPONSE REGULATOR receiver
E3T13_RS01975	COG5002	protein histidine kinase activity
E3T13_RS01985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3T13_RS01985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3T13_RS01990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3T13_RS02015	COG1484	DNA-dependent DNA replication
E3T13_RS02030	COG0833	amino acid
E3T13_RS02050	COG4112	unkown
E3T13_RS02085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3T13_RS02100	COG0113	porphobilinogen synthase activity
E3T13_RS02120	COG2818	Glycosylase
E3T13_RS02130	COG0285	dihydrofolate synthase activity
E3T13_RS02135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E3T13_RS02180	COG2868	ribosomal protein
E3T13_RS02220	COG1862	Preprotein translocase
E3T13_RS02225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3T13_RS02225	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3T13_RS02230	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E3T13_RS02230	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3T13_RS02275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3T13_RS02280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3T13_RS02285	COG1959	2 iron, 2 sulfur cluster binding
E3T13_RS02300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3T13_RS02305	COG1104	cysteine desulfurase activity
E3T13_RS02320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3T13_RS02370	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3T13_RS02375	COG1984	allophanate hydrolase subunit 2
E3T13_RS02380	COG0511	ligase activity, forming carbon-carbon bonds
E3T13_RS02385	COG0439	Biotin carboxylase
E3T13_RS02395	COG1914	H( )-stimulated, divalent metal cation uptake system
E3T13_RS02420	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E3T13_RS02425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E3T13_RS02435	COG1534	Rna-binding protein
E3T13_RS02445	COG1713	HD superfamily hydrolase involved in NAD metabolism
E3T13_RS02450	COG0799	negative regulation of ribosome biogenesis
E3T13_RS02455	COG2226	methyltransferase
E3T13_RS02465	COG2131	deaminase
E3T13_RS02470	COG0658	competence protein
E3T13_RS02470	COG2333	competence protein COMEC
E3T13_RS02475	COG1466	dna polymerase III delta subunit
E3T13_RS02490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3T13_RS02520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3T13_RS02525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3T13_RS02535	COG1030	water channel activity
E3T13_RS02550	COG1702	phosphate starvation-inducible protein PhoH
E3T13_RS02565	COG0295	cytidine deaminase activity
E3T13_RS02585	COG0517	IMP dehydrogenase activity
E3T13_RS02600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3T13_RS02605	COG2384	SAM-dependent methyltransferase
E3T13_RS02615	COG0513	Belongs to the DEAD box helicase family
E3T13_RS02625	COG1121	(ABC) transporter
E3T13_RS02630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3T13_RS02635	COG0735	belongs to the Fur family
E3T13_RS02655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3T13_RS02665	COG4483	Protein conserved in bacteria
E3T13_RS02670	COG1940	carbohydrate kinase activity
E3T13_RS02675	COG0011	TIGRFAM Protein of
E3T13_RS02680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3T13_RS02685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3T13_RS02690	COG1459	type II secretion system
E3T13_RS02695	COG4537	Required for transformation and DNA binding
E3T13_RS02740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3T13_RS02745	COG0095	Lipoate-protein ligase
E3T13_RS02760	COG0006	proline dipeptidase activity
E3T13_RS02770	COG0511	ligase activity, forming carbon-carbon bonds
E3T13_RS02775	COG0439	Biotin carboxylase
E3T13_RS02780	COG1302	Protein conserved in bacteria
E3T13_RS02810	COG0497	DNA recombination
E3T13_RS02815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3T13_RS02820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E3T13_RS02825	COG0022	dehydrogenase e1 component
E3T13_RS02830	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3T13_RS02840	COG4129	membrane
E3T13_RS02850	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3T13_RS02880	COG1609	Transcriptional regulator
E3T13_RS02885	COG0366	Alpha amylase catalytic
E3T13_RS02895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3T13_RS02910	COG4221	oxidoreductase activity
E3T13_RS02920	COG0667	Aldo Keto reductase
E3T13_RS02925	COG0494	nUDIX hydrolase
E3T13_RS02930	COG0735	belongs to the Fur family
E3T13_RS02955	COG1187	pseudouridine synthase activity
E3T13_RS02960	COG0745	RESPONSE REGULATOR receiver
E3T13_RS02995	COG1141	Ferredoxin
E3T13_RS03005	COG0514	ATP-dependent DNA helicase (RecQ)
E3T13_RS03020	COG0492	ferredoxin-NADP+ reductase activity
E3T13_RS03075	COG0142	geranyltranstransferase activity
E3T13_RS03110	COG4347	Protein of unknown function (DUF1405)
E3T13_RS03115	COG2738	Putative neutral zinc metallopeptidase
E3T13_RS03120	COG1694	Mazg nucleotide pyrophosphohydrolase
E3T13_RS03125	COG0438	transferase activity, transferring glycosyl groups
E3T13_RS03150	COG3935	DnaD domain protein
E3T13_RS03155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3T13_RS03165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3T13_RS03165	COG4499	WXG100 protein secretion system (Wss), protein YukC
E3T13_RS03195	COG0116	Belongs to the methyltransferase superfamily
E3T13_RS03210	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3T13_RS03215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3T13_RS03230	COG0531	amino acid
E3T13_RS03250	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3T13_RS03310	COG2826	transposase and inactivated derivatives, IS30 family
E3T13_RS03330	COG0671	phosphoesterase, PA-phosphatase related
E3T13_RS03380	COG4548	von Willebrand factor, type A
E3T13_RS03450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3T13_RS03455	COG0527	aspartate kinase activity
E3T13_RS03460	COG0488	(ABC) transporter
E3T13_RS03475	COG0573	inorganic phosphate transmembrane transporter activity
E3T13_RS03480	COG0581	inorganic phosphate transmembrane transporter activity
E3T13_RS03490	COG0704	Plays a role in the regulation of phosphate uptake
E3T13_RS03540	COG2348	transferase activity, transferring amino-acyl groups
E3T13_RS03575	COG0512	Glutamine amidotransferase of anthranilate synthase
E3T13_RS03580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3T13_RS03585	COG1363	Peptidase, m42
E3T13_RS03595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3T13_RS03610	COG1316	TRANSCRIPTIONal
E3T13_RS03615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3T13_RS03625	COG0628	permease
E3T13_RS03640	COG1115	amino acid carrier protein
E3T13_RS03650	COG0187	DNA topoisomerase II activity
E3T13_RS03665	COG0824	Thioesterase
E3T13_RS03675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3T13_RS03695	COG4846	Membrane protein involved in cytochrome C biogenesis
E3T13_RS03760	COG0833	amino acid
E3T13_RS03785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3T13_RS03790	COG0460	homoserine dehydrogenase
E3T13_RS03795	COG0527	aspartate kinase activity
E3T13_RS03810	COG1525	nuclease
E3T13_RS03820	COG2197	response regulator
E3T13_RS03835	COG1131	(ABC) transporter
E3T13_RS03940	COG2826	transposase and inactivated derivatives, IS30 family
E3T13_RS03980	COG2946	Replication initiation factor
E3T13_RS04000	COG0433	COG0433 Predicted ATPase
E3T13_RS04005	COG1674	ftsk spoiiie
E3T13_RS04035	COG2826	transposase and inactivated derivatives, IS30 family
E3T13_RS04050	COG0789	Transcriptional regulator
E3T13_RS04055	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E3T13_RS04070	COG1923	regulation of RNA biosynthetic process
E3T13_RS04095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3T13_RS04100	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3T13_RS04135	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3T13_RS04140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3T13_RS04140	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3T13_RS04145	COG1692	metallophosphoesterase
E3T13_RS04165	COG1546	Belongs to the CinA family
E3T13_RS04165	COG1058	Belongs to the CinA family
E3T13_RS04185	COG0300	oxidoreductase activity
E3T13_RS04190	COG0612	Peptidase, M16
E3T13_RS04195	COG0612	Peptidase, M16
E3T13_RS04200	COG2188	Transcriptional regulator
E3T13_RS04225	COG0196	riboflavin kinase activity
E3T13_RS04250	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E3T13_RS04255	COG0195	Participates in both transcription termination and antitermination
E3T13_RS04350	COG0758	DNA mediated transformation
E3T13_RS04355	COG2348	transferase activity, transferring amino-acyl groups
E3T13_RS04410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3T13_RS04420	COG0552	protein localization to endoplasmic reticulum
E3T13_RS04425	COG1196	nuclear chromosome segregation
E3T13_RS04470	COG1302	Protein conserved in bacteria
E3T13_RS04485	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3T13_RS04500	COG0631	protein serine/threonine phosphatase activity
E3T13_RS04510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3T13_RS04510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3T13_RS04525	COG2314	TM2 domain
E3T13_RS04535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3T13_RS04540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3T13_RS04600	COG2233	PERMEase
E3T13_RS04610	COG0564	pseudouridine synthase activity
E3T13_RS04620	COG2514	catechol 2,3-dioxygenase activity
E3T13_RS04635	COG3599	regulation of cell shape
E3T13_RS04640	COG2302	S4 RNA-binding domain
E3T13_RS04645	COG0762	integral membrane protein
E3T13_RS04655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3T13_RS04665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3T13_RS04695	COG4839	cell division protein FtsL
E3T13_RS04720	COG1011	Hydrolase
E3T13_RS04750	COG1288	antiporter activity
E3T13_RS04860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3T13_RS04865	COG1053	succinate dehydrogenase
E3T13_RS04870	COG2009	succinate dehydrogenase
E3T13_RS04895	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3T13_RS04895	COG1796	DNA polymerase
E3T13_RS04925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3T13_RS04940	COG4509	Sortase family
E3T13_RS04995	COG0742	ribosomal rna small subunit methyltransferase
E3T13_RS05010	COG0584	glycerophosphoryl diester phosphodiesterase
E3T13_RS05015	COG3679	Belongs to the UPF0342 family
E3T13_RS05020	COG2340	Cysteine-rich secretory protein family
E3T13_RS05040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3T13_RS05045	COG0772	Belongs to the SEDS family
E3T13_RS05055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E3T13_RS05075	COG0483	inositol monophosphate 1-phosphatase activity
E3T13_RS05100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3T13_RS05105	COG1177	transmembrane transport
E3T13_RS05110	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3T13_RS05175	COG0569	domain protein
E3T13_RS05180	COG1294	oxidase, subunit
E3T13_RS05185	COG1271	oxidase subunit
E3T13_RS05210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3T13_RS05225	COG4721	ABC-type cobalt transport system, permease component
E3T13_RS05230	COG4172	Belongs to the ABC transporter superfamily
E3T13_RS05235	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E3T13_RS05275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3T13_RS05290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3T13_RS05335	COG1316	TRANSCRIPTIONal
E3T13_RS05365	COG3594	Acyltransferase
E3T13_RS05395	COG2267	carboxylic ester hydrolase activity
E3T13_RS05405	COG1169	isochorismate synthase
E3T13_RS05415	COG1575	Belongs to the MenA family. Type 1 subfamily
E3T13_RS05420	COG0456	acetyltransferase
E3T13_RS05425	COG2314	TM2 domain
E3T13_RS05435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3T13_RS05495	COG4873	Protein conserved in bacteria
E3T13_RS05510	COG4903	ComK protein
E3T13_RS05525	COG0737	Belongs to the 5'-nucleotidase family
E3T13_RS05530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3T13_RS05540	COG0861	Integral membrane protein TerC family
E3T13_RS05590	COG1115	amino acid carrier protein
E3T13_RS05595	COG0628	permease
E3T13_RS05605	COG0569	domain protein
E3T13_RS05605	COG0475	glutathione-regulated potassium exporter activity
E3T13_RS05610	COG2239	Acts as a magnesium transporter
E3T13_RS05615	COG0564	pseudouridine synthase activity
E3T13_RS05625	COG2357	RelA SpoT domain protein
E3T13_RS05640	COG2346	COG2346, Truncated hemoglobins
E3T13_RS05650	COG1164	Oligoendopeptidase f
E3T13_RS05685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3T13_RS05695	COG4608	Belongs to the ABC transporter superfamily
E3T13_RS05700	COG0444	Belongs to the ABC transporter superfamily
E3T13_RS05705	COG0747	negative chemotaxis
E3T13_RS05710	COG2826	transposase and inactivated derivatives, IS30 family
E3T13_RS05720	COG4166	transmembrane transport
E3T13_RS05725	COG4608	Belongs to the ABC transporter superfamily
E3T13_RS05730	COG0444	Belongs to the ABC transporter superfamily
E3T13_RS05735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3T13_RS05740	COG0601	transmembrane transport
E3T13_RS05770	COG1881	PFAM PEBP family protein
E3T13_RS05810	COG0561	phosphatase activity
E3T13_RS05855	COG0398	Pfam SNARE associated Golgi protein
E3T13_RS05875	COG0584	glycerophosphoryl diester phosphodiesterase
E3T13_RS05890	COG1902	pentaerythritol trinitrate reductase activity
E3T13_RS05895	COG1098	S1 RNA binding domain
E3T13_RS05950	COG2050	protein possibly involved in aromatic compounds catabolism
E3T13_RS05955	COG2056	Na+-H+ antiporter family
E3T13_RS05960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3T13_RS05970	COG0316	Belongs to the HesB IscA family
E3T13_RS05980	COG1252	NADH dehydrogenase
E3T13_RS05985	COG4837	Protein of unknown function (DUF1462)
E3T13_RS05990	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3T13_RS05995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E3T13_RS06005	COG1696	Membrane protein involved in D-alanine export
E3T13_RS06035	COG2445	Protein of unknown function DUF86
E3T13_RS06045	COG4470	Protein conserved in bacteria
E3T13_RS06060	COG0730	response to heat
E3T13_RS06065	COG1801	Protein of unknown function DUF72
E3T13_RS06075	COG1253	flavin adenine dinucleotide binding
E3T13_RS06095	COG0822	iron-sulfur transferase activity
E3T13_RS06105	COG0719	Fe-S assembly protein
E3T13_RS06110	COG0396	ATPase activity
E3T13_RS06125	COG1464	Belongs to the NlpA lipoprotein family
E3T13_RS06130	COG2011	ABC-type metal ion transport system permease component
E3T13_RS06145	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3T13_RS06150	COG3878	Protein conserved in bacteria
E3T13_RS06165	COG1393	Belongs to the ArsC family
E3T13_RS06170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3T13_RS06195	COG1279	arginine transmembrane transporter activity
E3T13_RS06200	COG0406	alpha-ribazole phosphatase activity
E3T13_RS06240	COG1278	Cold shock
E3T13_RS06305	COG0557	exoribonuclease II activity
E3T13_RS06310	COG1647	Serine aminopeptidase, S33
E3T13_RS06315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3T13_RS06365	COG0281	malic enzyme
E3T13_RS06380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3T13_RS06435	COG3942	CHAP domain
E3T13_RS06435	COG1388	LysM domain
E3T13_RS06455	COG2826	transposase and inactivated derivatives, IS30 family
E3T13_RS06465	COG1040	competence protein
E3T13_RS06470	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E3T13_RS06480	COG1739	Uncharacterized protein family UPF0029
E3T13_RS06485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3T13_RS06540	COG4607	ABC-type enterochelin transport system periplasmic component
E3T13_RS06545	COG4604	ABC transporter, ATP-binding protein
E3T13_RS06550	COG4605	iron ion homeostasis
E3T13_RS06555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3T13_RS06560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3T13_RS06565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3T13_RS06585	COG3104	oligopeptide transport
E3T13_RS06610	COG1174	glycine betaine transport
E3T13_RS06615	COG1125	glycine betaine transport
E3T13_RS06615	COG0517	IMP dehydrogenase activity
E3T13_RS06620	COG0514	ATP-dependent DNA helicase (RecQ)
E3T13_RS06625	COG0488	(ABC) transporter
E3T13_RS06655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3T13_RS06660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3T13_RS06660	COG0512	Glutamine amidotransferase of anthranilate synthase
E3T13_RS06670	COG0720	synthase
E3T13_RS06705	COG0463	Glycosyl transferase, family 2
E3T13_RS06710	COG0656	L-ascorbic acid biosynthetic process
E3T13_RS06715	COG1253	flavin adenine dinucleotide binding
E3T13_RS06720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3T13_RS06725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3T13_RS06725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3T13_RS06725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3T13_RS06730	COG1105	Belongs to the carbohydrate kinase PfkB family
E3T13_RS06735	COG1349	DNA-binding transcription factor activity
E3T13_RS06740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3T13_RS06775	COG0471	metal ion transport
E3T13_RS06785	COG4989	oxidoreductase activity
E3T13_RS06790	COG0523	cobalamin synthesis protein
E3T13_RS06795	COG1846	Transcriptional regulator
E3T13_RS06800	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3T13_RS06805	COG4988	ABC transporter
E3T13_RS06825	COG1611	Belongs to the LOG family
E3T13_RS06860	COG3316	Transposase and inactivated derivatives
E3T13_RS06905	COG0583	DNA-binding transcription factor activity
E3T13_RS06975	COG1136	(ABC) transporter
E3T13_RS06975	COG0577	efflux transmembrane transporter activity
E3T13_RS07020	COG3316	Transposase and inactivated derivatives
E3T13_RS07030	COG2839	Protein conserved in bacteria
E3T13_RS07035	COG2814	Major facilitator Superfamily
E3T13_RS07040	COG0583	DNA-binding transcription factor activity
E3T13_RS07080	COG1388	LysM domain
E3T13_RS07080	COG3942	CHAP domain
E3T13_RS07085	COG0306	phosphate transporter
E3T13_RS07090	COG1392	Phosphate transport regulator
E3T13_RS07095	COG0577	efflux transmembrane transporter activity
E3T13_RS07100	COG1136	(ABC) transporter
E3T13_RS07135	COG3949	Membrane
E3T13_RS07155	COG2376	Dihydroxyacetone kinase
E3T13_RS07160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3T13_RS07165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3T13_RS07170	COG1120	ATPase activity
E3T13_RS07175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E3T13_RS07185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3T13_RS07190	COG1132	(ABC) transporter
E3T13_RS07195	COG1686	Belongs to the peptidase S11 family
E3T13_RS07200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3T13_RS07210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3T13_RS07215	COG1682	transport, permease protein
E3T13_RS07235	COG1321	iron dependent repressor
E3T13_RS07240	COG1121	(ABC) transporter
E3T13_RS07245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3T13_RS07250	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3T13_RS07260	COG2814	Major facilitator Superfamily
E3T13_RS07360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3T13_RS07395	COG1078	dGTPase activity
E3T13_RS07405	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3T13_RS07410	COG0667	Aldo Keto reductase
E3T13_RS07450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3T13_RS07470	COG0083	homoserine kinase activity
E3T13_RS07475	COG0095	Lipoate-protein ligase
E3T13_RS07580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3T13_RS07605	COG4932	domain protein
E3T13_RS07620	COG0561	phosphatase activity
E3T13_RS07630	COG1428	Deoxynucleoside kinase
E3T13_RS07635	COG1428	Deoxynucleoside kinase
E3T13_RS07640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3T13_RS07670	COG1473	amidohydrolase
E3T13_RS07710	COG2813	Specifically methylates the guanine in position
E3T13_RS07740	COG0250	Participates in transcription elongation, termination and antitermination
E3T13_RS07745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3T13_RS07770	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3T13_RS07790	COG4956	integral membrane protein (PIN domain superfamily)
E3T13_RS07795	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3T13_RS07810	COG3880	PFAM UvrB UvrC protein
E3T13_RS07820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3T13_RS07835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3T13_RS07930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3T13_RS07955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3T13_RS07970	COG1098	S1 RNA binding domain
E3T13_RS07980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3T13_RS07985	COG3956	TIGRFAM MazG family protein
E3T13_RS07990	COG2244	polysaccharide biosynthetic process
E3T13_RS08030	COG0251	oxidation-reduction process
E3T13_RS08035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3T13_RS08045	COG4466	Protein conserved in bacteria
E3T13_RS08055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3T13_RS08060	COG0084	hydrolase, TatD family'
E3T13_RS08070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3T13_RS08080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3T13_RS08090	COG1774	PSP1 C-terminal conserved region
E3T13_RS08095	COG0470	DNA polymerase III
E3T13_RS08100	COG3870	Protein conserved in bacteria
E3T13_RS08110	COG1982	Orn Lys Arg decarboxylase major
E3T13_RS08140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E3T13_RS08145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3T13_RS08165	COG2188	Transcriptional regulator
E3T13_RS08170	COG0366	Alpha amylase catalytic
E3T13_RS08175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3T13_RS08175	COG1263	PTS System
E3T13_RS08185	COG0493	'glutamate synthase
E3T13_RS08190	COG0069	glutamate synthase activity
E3T13_RS08190	COG0070	glutamate synthase
E3T13_RS08190	COG0067	glutamate synthase
E3T13_RS08195	COG0583	DNA-binding transcription factor activity
E3T13_RS08230	COG1464	Belongs to the NlpA lipoprotein family
E3T13_RS08235	COG2011	ABC-type metal ion transport system permease component
E3T13_RS08245	COG0626	cystathionine gamma-synthase activity
E3T13_RS08250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3T13_RS08255	COG0733	neurotransmitter:sodium symporter activity
E3T13_RS08265	COG1647	Serine aminopeptidase, S33
E3T13_RS08280	COG5609	conserved protein (DUF2294)
E3T13_RS08290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3T13_RS08315	COG0523	cobalamin synthesis protein
E3T13_RS08445	COG3759	membrane
E3T13_RS08480	COG2233	PERMEase
E3T13_RS08510	COG1823	symporter activity
E3T13_RS08600	COG5484	DNA packaging
E3T13_RS08600	COG3728	DNA packaging
E3T13_RS08710	COG0012	GTP binding
E3T13_RS08715	COG4481	Protein conserved in bacteria
E3T13_RS08720	COG0668	transmembrane transport
E3T13_RS08725	COG1475	DNA binding
E3T13_RS08730	COG0626	cystathionine gamma-synthase activity
E3T13_RS08735	COG0626	cystathionine gamma-synthase activity
E3T13_RS08740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3T13_RS08740	COG0646	methionine synthase
E3T13_RS08770	COG1131	(ABC) transporter
E3T13_RS08780	COG1476	TRANSCRIPTIONal
E3T13_RS08790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3T13_RS08795	COG0805	protein transport
E3T13_RS08800	COG0672	)-iron permease
E3T13_RS08805	COG2837	iron assimilation
E3T13_RS08810	COG2822	iron ion transport
E3T13_RS08815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3T13_RS08830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3T13_RS08835	COG0346	lactoylglutathione lyase activity
E3T13_RS08840	COG2271	Major facilitator Superfamily
E3T13_RS08865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3T13_RS08875	COG3037	sugar-specific permease SgaT UlaA
E3T13_RS08905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3T13_RS08955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3T13_RS08960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3T13_RS08975	COG2826	transposase and inactivated derivatives, IS30 family
E3T13_RS08995	COG0577	efflux transmembrane transporter activity
E3T13_RS09000	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E3T13_RS09005	COG1114	Component of the transport system for branched-chain amino acids
E3T13_RS09090	COG3942	CHAP domain
E3T13_RS09090	COG1388	LysM domain
E3T13_RS09165	COG2226	methyltransferase
E3T13_RS09170	COG2723	6-phospho-beta-galactosidase activity
E3T13_RS09175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3T13_RS09175	COG2190	(PTS) system
E3T13_RS09175	COG1263	PTS System
E3T13_RS09180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3T13_RS09190	COG2826	transposase and inactivated derivatives, IS30 family
E3T13_RS09230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3T13_RS09235	COG1063	alcohol dehydrogenase
E3T13_RS09245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3T13_RS09250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3T13_RS09255	COG1063	alcohol dehydrogenase
E3T13_RS09265	COG1063	alcohol dehydrogenase
E3T13_RS09275	COG1063	alcohol dehydrogenase
E3T13_RS09280	COG3775	system Galactitol-specific IIC component
E3T13_RS09285	COG3414	Phosphotransferase system galactitol-specific IIB component
E3T13_RS09305	COG1957	nucleoside hydrolase
E3T13_RS09310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3T13_RS09310	COG1263	PTS System
E3T13_RS09310	COG2190	(PTS) system
E3T13_RS09335	COG3189	MarR family transcriptional regulator
E3T13_RS09340	COG0747	negative chemotaxis
E3T13_RS09360	COG0318	PFAM AMP-dependent synthetase and ligase
E3T13_RS09365	COG1960	acyl-CoA dehydrogenase activity
E3T13_RS09375	COG0183	Belongs to the thiolase family
E3T13_RS09430	COG1755	Isoprenylcysteine carboxyl methyltransferase
E3T13_RS09440	COG0673	inositol 2-dehydrogenase activity
E3T13_RS09445	COG0673	inositol 2-dehydrogenase activity
E3T13_RS09450	COG3833	ABC-type maltose transport systems, permease component
E3T13_RS09455	COG1175	transmembrane transport
E3T13_RS09465	COG3842	ATPase activity
E3T13_RS09480	COG0405	Gamma-glutamyltransferase
E3T13_RS09490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3T13_RS09520	COG1737	Transcriptional regulator
E3T13_RS09550	COG3961	Belongs to the TPP enzyme family
E3T13_RS09555	COG1335	isochorismatase
E3T13_RS09560	COG1114	Component of the transport system for branched-chain amino acids
E3T13_RS09610	COG5609	conserved protein (DUF2294)
E3T13_RS09615	COG1960	acyl-CoA dehydrogenase activity
E3T13_RS09620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3T13_RS09655	COG2832	Protein of unknown function (DUF454)
E3T13_RS09665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3T13_RS09670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3T13_RS09680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3T13_RS09710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3T13_RS09720	COG1086	Polysaccharide biosynthesis protein
E3T13_RS09745	COG1012	belongs to the aldehyde dehydrogenase family
E3T13_RS09745	COG1454	alcohol dehydrogenase
E3T13_RS09760	COG0737	Belongs to the 5'-nucleotidase family
E3T13_RS09780	COG3639	organic phosphonate transmembrane transporter activity
E3T13_RS09800	COG2814	Major facilitator Superfamily
E3T13_RS09805	COG0813	purine-nucleoside phosphorylase activity
E3T13_RS09835	COG0438	transferase activity, transferring glycosyl groups
E3T13_RS09840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3T13_RS09845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3T13_RS09865	COG1475	DNA binding
E3T13_RS09870	COG0019	diaminopimelate decarboxylase activity
E3T13_RS09880	COG4264	IucA IucC family
E3T13_RS09885	COG4264	IucA IucC family
E3T13_RS09890	COG2814	Major facilitator Superfamily
E3T13_RS09895	COG4264	IucA IucC family
E3T13_RS09900	COG2423	ornithine cyclodeaminase activity
E3T13_RS09910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3T13_RS09915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3T13_RS09920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3T13_RS09935	COG1620	l-lactate permease
E3T13_RS09945	COG4716	Myosin-crossreactive antigen
E3T13_RS09950	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3T13_RS09960	COG1473	amidohydrolase
E3T13_RS09975	COG0823	Involved in the tonB-independent uptake of proteins
E3T13_RS10030	COG2814	Major facilitator Superfamily
E3T13_RS10050	COG4268	DNA restriction-modification system
E3T13_RS10055	COG1401	restriction endodeoxyribonuclease activity
E3T13_RS10065	COG2826	transposase and inactivated derivatives, IS30 family
E3T13_RS10090	COG0737	Belongs to the 5'-nucleotidase family
E3T13_RS10095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3T13_RS10105	COG4863	YycH protein
E3T13_RS10135	COG0305	Participates in initiation and elongation during chromosome replication
E3T13_RS10145	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E3T13_RS10155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3T13_RS10180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3T13_RS10200	COG2501	S4 domain
E3T13_RS10240	COG1475	DNA binding
E3T13_RS10260	COG1278	Cold shock
E3T13_RS10290	COG0577	efflux transmembrane transporter activity
E3T13_RS10295	COG1136	(ABC) transporter
E3T13_RS10310	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3T13_RS10320	COG2962	Rard protein
E3T13_RS10325	COG0471	metal ion transport
E3T13_RS10405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3T13_RS10455	COG1215	transferase activity, transferring glycosyl groups
E3T13_RS10460	COG1309	transcriptional regulator
E3T13_RS10490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3T13_RS10515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3T13_RS10525	COG0201	protein transport
E3T13_RS10540	COG1073	alpha beta
E3T13_RS10555	COG0438	transferase activity, transferring glycosyl groups
E3T13_RS10570	COG3433	isochorismatase activity
E3T13_RS10570	COG1535	isochorismatase
E3T13_RS10575	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3T13_RS10575	COG3942	CHAP domain
E3T13_RS10585	COG1482	cell wall glycoprotein biosynthetic process
E3T13_RS10590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3T13_RS10590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3T13_RS10590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3T13_RS10595	COG3711	transcriptional antiterminator
E3T13_RS10595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3T13_RS10615	COG1438	arginine binding
E3T13_RS10660	COG1846	Transcriptional regulator
E3T13_RS10670	COG1785	Belongs to the alkaline phosphatase family
E3T13_RS10680	COG0745	RESPONSE REGULATOR receiver
E3T13_RS10685	COG2205	protein histidine kinase activity
E3T13_RS10690	COG1136	(ABC) transporter
E3T13_RS10710	COG0386	Belongs to the glutathione peroxidase family
E3T13_RS10720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3T13_RS10735	COG2851	Citrate transporter
E3T13_RS10760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3T13_RS10765	COG1510	regulation of RNA biosynthetic process
E3T13_RS10795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3T13_RS10825	COG0531	amino acid
E3T13_RS10835	COG3527	Alpha-acetolactate decarboxylase
E3T13_RS10890	COG0167	dihydroorotate dehydrogenase activity
E3T13_RS11030	COG0436	Aminotransferase
E3T13_RS11075	COG2409	Drug exporters of the RND superfamily
E3T13_RS11100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3T13_RS11105	COG3425	synthase
E3T13_RS11115	COG3942	CHAP domain
E3T13_RS11125	COG0583	DNA-binding transcription factor activity
E3T13_RS11140	COG0028	Belongs to the TPP enzyme family
E3T13_RS11160	COG0657	acetylesterase activity
E3T13_RS11165	COG0697	spore germination
E3T13_RS11180	COG1760	l-serine dehydratase
E3T13_RS11185	COG1760	l-serine dehydratase
E3T13_RS11205	COG3764	Sortase (surface protein transpeptidase)
E3T13_RS11210	COG0561	phosphatase activity
E3T13_RS11230	COG2514	catechol 2,3-dioxygenase activity
E3T13_RS11240	COG1846	Transcriptional regulator
E3T13_RS11245	COG0346	lactoylglutathione lyase activity
E3T13_RS11250	COG0400	carboxylic ester hydrolase activity
E3T13_RS11270	COG1131	(ABC) transporter
E3T13_RS11275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3T13_RS11285	COG1279	arginine transmembrane transporter activity
E3T13_RS11290	COG0586	Pfam SNARE associated Golgi protein
E3T13_RS11295	COG2271	Major facilitator Superfamily
E3T13_RS11305	COG4876	unkown
E3T13_RS11310	COG2357	RelA SpoT domain protein
E3T13_RS11315	COG0789	Transcriptional regulator
E3T13_RS11320	COG1802	Transcriptional regulator
E3T13_RS11325	COG1070	Carbohydrate kinase
E3T13_RS11370	COG0494	nUDIX hydrolase
E3T13_RS11445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3T13_RS11450	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3T13_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
E3T13_RS11460	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3T13_RS11480	COG0747	negative chemotaxis
E3T13_RS11485	COG0601	transmembrane transport
E3T13_RS11490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3T13_RS11500	COG1124	(ABC) transporter
E3T13_RS11515	COG0069	glutamate synthase activity
E3T13_RS11520	COG4808	Protein conserved in bacteria
E3T13_RS11525	COG1363	Peptidase, m42
E3T13_RS11530	COG4619	ABC transporter
E3T13_RS11540	COG2814	Major facilitator Superfamily
E3T13_RS11545	COG2272	Belongs to the type-B carboxylesterase lipase family
E3T13_RS11550	COG0531	amino acid
E3T13_RS11555	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E3T13_RS11575	COG1174	glycine betaine transport
E3T13_RS11585	COG1174	glycine betaine transport
E3T13_RS11595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3T13_RS11610	COG0531	amino acid
E3T13_RS11620	COG1113	amino acid transport
E3T13_RS11640	COG2814	Major facilitator Superfamily
E3T13_RS11650	COG1929	Belongs to the glycerate kinase type-1 family
E3T13_RS11670	COG1132	(ABC) transporter
E3T13_RS11680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3T13_RS11685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3T13_RS11695	COG0156	8-amino-7-oxononanoate synthase activity
E3T13_RS11735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E3T13_RS11750	COG2814	Major facilitator Superfamily
E3T13_RS11755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3T13_RS11760	COG0765	amino acid transport
E3T13_RS11765	COG1126	abc transporter atp-binding protein
E3T13_RS11800	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3T13_RS11800	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3T13_RS11815	COG2116	formate transmembrane transporter activity
E3T13_RS11820	COG0454	-acetyltransferase
E3T13_RS11830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3T13_RS11835	COG2146	nitrite reductase [NAD(P)H] activity
E3T13_RS11845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3T13_RS11850	COG1140	nitrate reductase beta subunit
E3T13_RS11860	COG2181	nitrate reductase activity
E3T13_RS11925	COG3871	stress protein (general stress protein 26)
E3T13_RS11940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3T13_RS11940	COG1263	PTS System
E3T13_RS11955	COG1511	domain protein
E3T13_RS11980	COG0604	alcohol dehydrogenase
E3T13_RS12000	COG1620	l-lactate permease
E3T13_RS12015	COG1131	(ABC) transporter
E3T13_RS12075	COG2814	Major facilitator Superfamily
E3T13_RS12090	COG1566	PFAM secretion protein HlyD family protein
E3T13_RS12095	COG2814	Major facilitator Superfamily
E3T13_RS12105	COG0657	acetylesterase activity
E3T13_RS12120	COG0598	Magnesium transport protein CorA
E3T13_RS12130	COG0786	glutamate:sodium symporter activity
E3T13_RS12145	COG4152	abc transporter atp-binding protein
E3T13_RS12150	COG1668	transmembrane transport
E3T13_RS12170	COG2258	MOSC domain
E3T13_RS12195	COG0583	DNA-binding transcription factor activity
E3T13_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
E3T13_RS12235	COG1737	Transcriptional regulator
E3T13_RS12240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3T13_RS12240	COG1263	PTS System
E3T13_RS12255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3T13_RS12275	COG1113	amino acid transport
E3T13_RS12355	COG1757	Na H antiporter
E3T13_RS12425	COG4413	Urea transporter
E3T13_RS12430	COG1960	acyl-CoA dehydrogenase activity
E3T13_RS12445	COG1268	BioY protein
E3T13_RS12460	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3T13_RS12465	COG4149	molybdate abc transporter
E3T13_RS12470	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3T13_RS12475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3T13_RS12495	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3T13_RS12555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3T13_RS12600	COG2252	PERMEase
E3T13_RS12715	COG0201	protein transport
E3T13_RS12810	COG0028	Belongs to the TPP enzyme family
E3T13_RS12815	COG3527	Alpha-acetolactate decarboxylase
E3T13_RS12835	COG5492	domain, Protein
E3T13_RS12845	COG0789	Transcriptional regulator
E3T13_RS12850	COG0656	L-ascorbic acid biosynthetic process
E3T13_RS12925	COG2130	NADP-dependent
E3T13_RS12935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3T13_RS12960	COG2814	Major facilitator Superfamily
E3T13_RS12965	COG4264	IucA IucC family
E3T13_RS12970	COG3457	Alanine racemase
E3T13_RS12980	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3T13_RS12985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3T13_RS12990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3T13_RS13005	COG1988	membrane-bound metal-dependent
E3T13_RS13015	COG1272	protein, Hemolysin III
E3T13_RS13035	COG0489	protein tyrosine kinase activity
E3T13_RS13095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E3T13_RS13125	COG3711	transcriptional antiterminator
E3T13_RS13140	COG1119	ATPase activity
E3T13_RS13145	COG0561	phosphatase activity
E3T13_RS13175	COG0640	Transcriptional regulator
E3T13_RS13180	COG0702	epimerase
E3T13_RS13185	COG1482	cell wall glycoprotein biosynthetic process
E3T13_RS13205	COG0783	Belongs to the Dps family
E3T13_RS13215	COG0813	purine-nucleoside phosphorylase activity
E3T13_RS13260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3T13_RS13300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3T13_RS13320	COG2890	protein-(glutamine-N5) methyltransferase activity
E3T13_RS13325	COG0009	L-threonylcarbamoyladenylate synthase
E3T13_RS13350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3T13_RS13425	COG0629	single-stranded DNA binding
E3T13_RS13465	COG1418	mRNA catabolic process
E3T13_RS13475	COG1937	Protein conserved in bacteria
E3T13_RS13495	COG0772	Belongs to the SEDS family
E3T13_RS13505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3T13_RS13515	COG0745	RESPONSE REGULATOR receiver
E3T13_RS13520	COG2205	protein histidine kinase activity
E3T13_RS13550	COG3428	Bacterial PH domain
E3T13_RS13580	COG2208	phosphoserine phosphatase activity
E3T13_RS13585	COG1366	Belongs to the anti-sigma-factor antagonist family
E3T13_RS13595	COG1191	sigma factor activity
E3T13_RS13600	COG2183	response to ionizing radiation
E3T13_RS13675	COG0028	Belongs to the TPP enzyme family
E3T13_RS13690	COG0802	atpase or kinase
E3T13_RS13695	COG1214	PFAM Peptidase M22, glycoprotease
E3T13_RS13700	COG0456	acetyltransferase
E3T13_RS13710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E3T13_RS13720	COG0488	(ABC) transporter
E3T13_RS13730	COG2391	methyltransferase activity
E3T13_RS13735	COG0425	Belongs to the sulfur carrier protein TusA family
E3T13_RS13740	COG0004	ammonium transporteR
E3T13_RS13745	COG1609	Transcriptional regulator
E3T13_RS13750	COG1621	beta-fructofuranosidase activity
E3T13_RS13755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3T13_RS13815	COG0582	viral genome integration into host DNA
E3T13_RS13900	COG3728	DNA packaging
E3T13_RS13900	COG5484	DNA packaging
E3T13_RS13935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3T13_RS13955	COG3568	Endonuclease Exonuclease Phosphatase
E3T13_RS14075	COG1484	DNA-dependent DNA replication