locus-tag	class	description
E3S72_RS00020	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E3S72_RS00120	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
E3S72_RS00185	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
E3S72_RS00200	ENOG4105CJ1	ABC, transporter
E3S72_RS00250	ENOG4108FPN	Integrase
E3S72_RS00255	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3S72_RS00295	ENOG4105C26	Dehydrogenase
E3S72_RS00320	ENOG4105C8P	)-transporter
E3S72_RS00330	ENOG4105CQC	Prephenate dehydratase
E3S72_RS00335	ENOG4107QN4	Catalyzes the production of nitric oxide (By similarity)
E3S72_RS00340	ENOG4105DAP	Nicotinate phosphoribosyltransferase
E3S72_RS00365	ENOG4107DDB	Cysteine protease able to
E3S72_RS00375	ENOG4105KGF	protein, YerC YecD
E3S72_RS00385	ENOG4105C4R	Atp-dependent dna helicase
E3S72_RS00500	ENOG4105ENE	Histidine kinase
E3S72_RS00510	ENOG4107U9T	Pfam:Ribonuclease_BN
E3S72_RS00535	ENOG4108S4H	thioesterase Superfamily protein
E3S72_RS00570	ENOG4105EY8	ABC transporter
E3S72_RS00580	ENOG41067AE	Membrane-bound metal-dependent hydrolase
E3S72_RS00605	ENOG4107NBY	Membrane
E3S72_RS00615	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3S72_RS00620	ENOG4108M3J	Dehydrogenase
E3S72_RS00625	ENOG4105G5W	regulator Fur family
E3S72_RS00795	ENOG4105E5Q	amino acid AbC transporter
E3S72_RS00800	ENOG4105CDA	abc transporter atp-binding protein
E3S72_RS00805	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E3S72_RS00830	ENOG4105C9Q	fumarate hydratase class II
E3S72_RS00835	ENOG4108YBP	pseudouridine synthase
E3S72_RS00840	ENOG4105BZU	Histidine kinase
E3S72_RS00845	ENOG4105WH1	Two component transcriptional regulator luxr family
E3S72_RS00870	ENOG4107VRP	DNA repair exonuclease
E3S72_RS00900	ENOG4105K59	histidine triad (HIT) protein
E3S72_RS00935	ENOG4105C1Q	protoporphyrinogen oxidase
E3S72_RS01180	ENOG4105E09	nadh pyrophosphatase
E3S72_RS01205	ENOG4105CV8	reductase
E3S72_RS01215	ENOG4105WMR	Protein CrcB homolog
E3S72_RS01220	ENOG4106A8V	Protein CrcB homolog
E3S72_RS01230	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E3S72_RS01260	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
E3S72_RS01265	ENOG4107R3E	Citrate transporter
E3S72_RS01280	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E3S72_RS01285	ENOG4108R6K	riboflavin synthase, subunit alpha
E3S72_RS01290	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E3S72_RS01310	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
E3S72_RS01325	ENOG4105N5T	Radical SAM Protein
E3S72_RS01330	ENOG410605W	Major Facilitator
E3S72_RS01350	ENOG4105CBX	hi0933 family
E3S72_RS01375	ENOG4105F0I	Aminotransferase
E3S72_RS01380	ENOG4108V15	phosphotransferase enzyme family
E3S72_RS01390	ENOG4105C8F	Beta-lactamase domain protein
E3S72_RS01415	ENOG4108VDD	TRNA binding domain protein
E3S72_RS01445	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E3S72_RS01455	ENOG4105ETE	Transcriptional regulator (LacI family
E3S72_RS01460	ENOG4105DGU	Histone deacetylase
E3S72_RS01465	ENOG4105F1V	Acetoin utilization protein
E3S72_RS01505	ENOG4105C0H	protease
E3S72_RS01510	ENOG4105F6E	Acyl-transferase
E3S72_RS01530	ENOG4108JQ1	Dehydrogenase
E3S72_RS01535	ENOG4105C5R	Aminotransferase
E3S72_RS01540	ENOG4108X3M	OsmC Ohr family protein
E3S72_RS01545	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E3S72_RS01585	ENOG4105EJ9	Membrane
E3S72_RS01590	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E3S72_RS01640	ENOG4105SFS	phosphoesterase RecJ domain protein
E3S72_RS01645	ENOG4105C0B	DNA polymerase III (alpha subunit)
E3S72_RS01650	ENOG4105C6K	Malic enzyme
E3S72_RS01675	ENOG4105C85	amino acid
E3S72_RS01680	ENOG4105BZN	citrate synthase
E3S72_RS01685	ENOG4108HMX	isocitrate dehydrogenase (NADP)
E3S72_RS01690	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3S72_RS01695	ENOG4105BZU	Histidine kinase
E3S72_RS01705	ENOG4105C2M	dna polymerase I
E3S72_RS01710	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E3S72_RS01720	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3S72_RS01750	ENOG4108IQI	permease
E3S72_RS01770	ENOG4105U6W	MutT NUDIX family protein
E3S72_RS01820	ENOG4105D52	delta-aminolevulinic acid dehydratase
E3S72_RS01840	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E3S72_RS01850	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E3S72_RS01855	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
E3S72_RS01900	ENOG4105X36	(ribosomal) protein
E3S72_RS01940	ENOG4105VIE	preprotein translocase, subunit YajC
E3S72_RS01945	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3S72_RS01950	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E3S72_RS01995	ENOG4105CUZ	uba thif-type nad fad binding protein
E3S72_RS02000	ENOG4105D1H	recombination factor protein RarA
E3S72_RS02020	ENOG4105DEN	Luciferase family
E3S72_RS02025	ENOG4105C3J	Cysteine desulfurase
E3S72_RS02040	ENOG4105C7H	Helicase, RecD TraA family
E3S72_RS02070	ENOG4105XYU	peptidase (U32 family)
E3S72_RS02075	ENOG4105CFP	Peptidase U32
E3S72_RS02090	ENOG4105P4J	Allophanate hydrolase, subunit 1
E3S72_RS02100	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E3S72_RS02105	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E3S72_RS02115	ENOG4105C5A	transporter
E3S72_RS02140	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
E3S72_RS02145	ENOG4105CQW	ribosome biogenesis GTPase YqeH
E3S72_RS02155	ENOG410812S	Rna-binding protein
E3S72_RS02165	ENOG4108WF2	Metal Dependent Phosphohydrolase
E3S72_RS02170	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
E3S72_RS02175	ENOG4105DXX	methyltransferase
E3S72_RS02180	ENOG4105BZM	domain protein
E3S72_RS02185	ENOG4108UK2	deaminase
E3S72_RS02190	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
E3S72_RS02195	ENOG4105TQK	DNA polymerase iii, delta' subunit
E3S72_RS02210	ENOG4105CSA	Coproporphyrinogen iii oxidase
E3S72_RS02240	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E3S72_RS02245	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E3S72_RS02255	ENOG4105F7J	membrane-bound serine protease
E3S72_RS02270	ENOG4105C9A	Phoh family
E3S72_RS02285	ENOG4105KG3	cytidine deaminase
E3S72_RS02315	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E3S72_RS02320	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3S72_RS02330	ENOG4105EGD	dinuclear metal center protein, YbgI family
E3S72_RS02335	ENOG4105C1J	atp-dependent rna helicase
E3S72_RS02345	ENOG4105FDK	ABC transporter
E3S72_RS02350	ENOG4105FAV	ABC, transporter
E3S72_RS02355	ENOG4105N80	Ferric uptake regulator, Fur family
E3S72_RS02365	ENOG4107RF6	penicillin-binding protein
E3S72_RS02375	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E3S72_RS02400	ENOG4105C5X	domain protein
E3S72_RS02410	ENOG4105D7Q	type ii secretion system
E3S72_RS02415	ENOG4106855	Competence protein
E3S72_RS02460	ENOG4105WZW	rhodanese family
E3S72_RS02465	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
E3S72_RS02480	ENOG4105DC7	peptidase M24
E3S72_RS02495	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E3S72_RS02500	ENOG4108ZSR	alkaline shock protein
E3S72_RS02530	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E3S72_RS02545	ENOG4105CPP	Dehydrogenase, E1 component
E3S72_RS02550	ENOG4105C7S	Dehydrogenase
E3S72_RS02560	ENOG4108QEG	Membrane
E3S72_RS02570	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
E3S72_RS02575	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
E3S72_RS02610	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
E3S72_RS02620	ENOG4105II7	pyrroline-5-carboxylate reductase
E3S72_RS02625	ENOG4105PDP	Short chain dehydrogenase
E3S72_RS02635	ENOG4105CPC	Aldo Keto reductase
E3S72_RS02640	ENOG4108YZ4	nudix hydrolase
E3S72_RS02645	ENOG4105I3K	Ferric uptake regulator, Fur family
E3S72_RS02650	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3S72_RS02670	ENOG4105FE9	pseudouridine synthase
E3S72_RS02675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E3S72_RS02680	ENOG4105BZU	Histidine kinase
E3S72_RS02730	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E3S72_RS02735	ENOG4106BU8	elastin-binding protein ebpS
E3S72_RS02745	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
E3S72_RS02750	ENOG4105HDK	L-asparaginase
E3S72_RS02770	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E3S72_RS02785	ENOG4105K70	DNA-binding protein
E3S72_RS02800	ENOG4105EAH	synthase
E3S72_RS02850	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
E3S72_RS02855	ENOG4105CPK	Glycosyl transferase (Group 1
E3S72_RS02885	ENOG4105CSM	endonuclease III
E3S72_RS02895	ENOG4105BZ4	penicillin-binding protein
E3S72_RS02930	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E3S72_RS02945	ENOG410890F	Dynamin family
E3S72_RS02960	ENOG4105C7B	Threonine dehydratase
E3S72_RS02965	ENOG4107R7I	amino acid
E3S72_RS03015	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
E3S72_RS03025	ENOG4108FKN	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E3S72_RS03035	ENOG4105C5Y	PTS System
E3S72_RS03045	ENOG4105CN1	protease
E3S72_RS03060	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E3S72_RS03090	ENOG4105C7S	Dehydrogenase
E3S72_RS03110	ENOG4107T89	von Willebrand factor, type A
E3S72_RS03150	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E3S72_RS03155	ENOG4108XFP	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E3S72_RS03180	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E3S72_RS03185	ENOG4105CFH	Aspartokinase
E3S72_RS03190	ENOG4105C5H	ABC transporter
E3S72_RS03210	ENOG4105C8U	phosphate abc transporter
E3S72_RS03215	ENOG4105E2Z	phosphate ABC transporter (Permease
E3S72_RS03225	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E3S72_RS03230	ENOG4105DPN	Oligoendopeptidase f
E3S72_RS03245	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E3S72_RS03250	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3S72_RS03260	ENOG4108JMM	(ABC) transporter
E3S72_RS03270	ENOG4108KP7	hydrolase
E3S72_RS03280	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
E3S72_RS03285	ENOG4108RMH	femAB family
E3S72_RS03315	ENOG4105DDQ	anthranilate synthase
E3S72_RS03320	ENOG4105CRQ	synthase (Component I)
E3S72_RS03325	ENOG4105DER	m42 family
E3S72_RS03330	ENOG4105EVN	Prephenate dehydrogenase
E3S72_RS03335	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E3S72_RS03345	ENOG4108RCF	TRANSCRIPTIONal
E3S72_RS03350	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E3S72_RS03355	ENOG4105FF5	Membrane
E3S72_RS03385	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3S72_RS03405	ENOG4108I0Z	Aconitate hydratase
E3S72_RS03410	ENOG4105C94	Transporter
E3S72_RS03445	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E3S72_RS03465	ENOG4105K4I	Scp-like extracellular
E3S72_RS03495	ENOG4108IQI	permease
E3S72_RS03520	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
E3S72_RS03525	ENOG4105D6E	homoserine dehydrogenase
E3S72_RS03530	ENOG4105CFH	Aspartokinase
E3S72_RS03555	ENOG4108S01	response regulator
E3S72_RS03570	ENOG4108M15	ABC transporter
E3S72_RS03575	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E3S72_RS03645	ENOG4105C5F	glutamine synthetase
E3S72_RS03650	ENOG4105KV4	Transcriptional regulator
E3S72_RS03655	ENOG4105CXI	aluminum resistance protein
E3S72_RS03660	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E3S72_RS03665	ENOG4108V06	Glutathione peroxidase
E3S72_RS03670	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E3S72_RS03695	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E3S72_RS03700	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
E3S72_RS03735	ENOG4105DQU	oxidoreductase, subunit beta
E3S72_RS03740	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
E3S72_RS03745	ENOG4105D48	metallophosphoesterase
E3S72_RS03765	ENOG4105CEV	competence damage-inducible protein
E3S72_RS03770	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E3S72_RS03785	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
E3S72_RS03800	ENOG4105FDP	GntR family transcriptional regulator
E3S72_RS03805	ENOG4105CNU	cell division protein FtsK
E3S72_RS03825	ENOG4105DTN	riboflavin biosynthesis protein ribF
E3S72_RS03850	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
E3S72_RS03855	ENOG4105CHV	Transcription elongation factor NusA
E3S72_RS03880	ENOG4105KNE	Phosphatidate cytidylyltransferase
E3S72_RS03885	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E3S72_RS03945	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3S72_RS03950	ENOG4105C79	DNA protecting protein DprA
E3S72_RS03955	ENOG4108RMH	femAB family
E3S72_RS03965	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E3S72_RS03980	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
E3S72_RS04020	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E3S72_RS04025	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E3S72_RS04040	ENOG4105CHR	reductase
E3S72_RS04045	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E3S72_RS04060	ENOG4105CB5	ATP-dependent DNA helicase recG
E3S72_RS04070	ENOG4108ZAA	Alkaline-shock protein
E3S72_RS04085	ENOG4105DJV	ribulose-phosphate 3-epimerase
E3S72_RS04090	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E3S72_RS04100	ENOG4108ZF3	Phosphatase
E3S72_RS04110	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E3S72_RS04120	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E3S72_RS04125	ENOG4105YB8	TM2 domain containing protein
E3S72_RS04135	ENOG4105C25	Primosomal protein n'
E3S72_RS04140	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E3S72_RS04150	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E3S72_RS04155	ENOG4105F23	Fibronectin-binding protein
E3S72_RS04170	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E3S72_RS04185	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E3S72_RS04190	ENOG4105CD3	dihydroorotase
E3S72_RS04210	ENOG4105C34	Pseudouridine synthase
E3S72_RS04225	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
E3S72_RS04240	ENOG4105DBK	s4 domain protein
E3S72_RS04245	ENOG41067XK	integral membrane protein
E3S72_RS04255	ENOG4105DFA	alanine racemase domain protein
E3S72_RS04260	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E3S72_RS04265	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E3S72_RS04270	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E3S72_RS04275	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
E3S72_RS04290	ENOG4105CJN	penicillin-binding protein
E3S72_RS04295	ENOG41068DC	Essential cell division protein (By similarity)
E3S72_RS04355	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E3S72_RS04365	ENOG4105DBV	ornithine carbamoyltransferase
E3S72_RS04395	ENOG4106UK0	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity
E3S72_RS04455	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E3S72_RS04465	ENOG4105E33	succinate dehydrogenase
E3S72_RS04475	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
E3S72_RS04500	ENOG4105DCG	PHP domain protein
E3S72_RS04520	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E3S72_RS04530	ENOG4108RWN	rrna methyltransferase
E3S72_RS04545	ENOG4105KFN	sortase, SrtB family
E3S72_RS04600	ENOG4106H78	methyltransferase
E3S72_RS04645	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
E3S72_RS04650	ENOG4105CNI	cell division protein FtsW
E3S72_RS04670	ENOG4105CI3	gtp-binding protein typa
E3S72_RS04680	ENOG4105ECY	inositol monophosphatase
E3S72_RS04705	ENOG4107RUE	extracellular solute-binding protein family 1
E3S72_RS04710	ENOG4105D38	putrescine abc transporter
E3S72_RS04715	ENOG4105F38	ABC transporter, permease
E3S72_RS04735	ENOG4107QN2	dihydrolipoyl dehydrogenase
E3S72_RS04740	ENOG4105C7S	Dehydrogenase
E3S72_RS04745	ENOG4105CPP	Dehydrogenase, E1 component
E3S72_RS04750	ENOG4107RUY	(E1 component), alpha subunit
E3S72_RS04760	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E3S72_RS04780	ENOG4107ZYR	domain protein
E3S72_RS04795	ENOG41067VN	Glutaredoxin
E3S72_RS04805	ENOG4105KRI	phosphocarrier protein (HPr
E3S72_RS04815	ENOG4105DR4	Methyltransferase
E3S72_RS04835	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
E3S72_RS04840	ENOG4108JJB	ABC transporter
E3S72_RS04845	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
E3S72_RS04850	ENOG4105C12	Phosphoribosylglycinamide synthetase
E3S72_RS04860	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E3S72_RS04870	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E3S72_RS04880	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
E3S72_RS04885	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
E3S72_RS04895	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E3S72_RS04900	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E3S72_RS04940	ENOG4108A04	Beta-lactamase
E3S72_RS04945	ENOG4108KGH	TRANSCRIPTIONal
E3S72_RS04955	ENOG41082BV	acetyltransferase
E3S72_RS04975	ENOG4108TGC	Acyltransferase
E3S72_RS04980	ENOG4105CHM	Aminotransferase
E3S72_RS05000	ENOG4108IPT	Naphthoate synthase
E3S72_RS05005	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E3S72_RS05015	ENOG4105E4F	Isochorismate synthase
E3S72_RS05025	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
E3S72_RS05030	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
E3S72_RS05035	ENOG4105YB8	TM2 domain containing protein
E3S72_RS05045	ENOG4108HUF	Transporter
E3S72_RS05065	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E3S72_RS05115	ENOG4105XVF	Competence transcription factor
E3S72_RS05130	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
E3S72_RS05140	ENOG4105C0H	protease
E3S72_RS05145	ENOG4107TS3	membrane protein, TerC
E3S72_RS05170	ENOG4108PK2	permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence
E3S72_RS05185	ENOG4105BZG	amino acid carrier protein
E3S72_RS05190	ENOG4105C02	permease
E3S72_RS05205	ENOG4105CJW	magnesium transporter
E3S72_RS05210	ENOG4105EMS	pseudouridine synthase
E3S72_RS05235	ENOG4108Z18	K06886 hemoglobin
E3S72_RS05240	ENOG4105T58	Dithiol-disulfide isomerase
E3S72_RS05245	ENOG4105DPN	Oligoendopeptidase f
E3S72_RS05265	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
E3S72_RS05270	ENOG4105C31	Tryptophanyl-tRNA synthetase
E3S72_RS05275	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3S72_RS05285	ENOG4108JQ7	(ABC) transporter
E3S72_RS05295	ENOG4105DEF	Extracellular solute-binding protein, family 5
E3S72_RS05305	ENOG4108JQ7	(ABC) transporter
E3S72_RS05315	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3S72_RS05320	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E3S72_RS05330	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3S72_RS05350	ENOG4105KIS	phospholipid-binding protein
E3S72_RS05365	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E3S72_RS05375	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3S72_RS05380	ENOG4105EXC	Acyl-transferase
E3S72_RS05390	ENOG4108KP7	hydrolase
E3S72_RS05420	ENOG4105C3F	Signal peptidase i
E3S72_RS05450	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
E3S72_RS05455	ENOG4105D82	Glutamate dehydrogenase
E3S72_RS05460	ENOG4105C8Y	Acetylornithine aminotransferase
E3S72_RS05465	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3S72_RS05470	ENOG41060GV	RNA binding s1 domain protein
E3S72_RS05525	ENOG4105KA0	thioesterase Superfamily protein
E3S72_RS05535	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E3S72_RS05545	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E3S72_RS05565	ENOG41083MR	nifu domain-containing protein
E3S72_RS05570	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
E3S72_RS05580	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
E3S72_RS05625	ENOG4105MMD	transcriptional regulator
E3S72_RS05645	ENOG4105I3N	Conserved Protein
E3S72_RS05705	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
E3S72_RS05725	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
E3S72_RS05835	ENOG4105IG6	Phage terminase, large subunit
E3S72_RS05870	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E3S72_RS05915	ENOG4106CVF	DNA replication protein
E3S72_RS06025	ENOG4108UNV	SUF system FeS assembly protein, NifU family
E3S72_RS06030	ENOG4105C9B	Cysteine desulfurase
E3S72_RS06035	ENOG4105JRK	feS assembly protein SufD
E3S72_RS06040	ENOG4105C3K	feS assembly ATPase SufC
E3S72_RS06055	ENOG4105D01	(LipO)protein
E3S72_RS06060	ENOG4108UMI	ABC transporter, permease
E3S72_RS06065	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E3S72_RS06080	ENOG4108XI2	Domain of unknown function (DUF1963)
E3S72_RS06095	ENOG41080E8	Transcriptional regulator, Spx MgsR family
E3S72_RS06100	ENOG4105SZ6	Thioredoxin
E3S72_RS06125	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
E3S72_RS06130	ENOG4105CVJ	phosphoglycerate mutase
E3S72_RS06170	ENOG4105VEQ	Cold shock protein
E3S72_RS06175	ENOG4107Y9E	nuclease
E3S72_RS06195	ENOG4106HV3	Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps
E3S72_RS06195	ENOG4106HV3	Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps
E3S72_RS06240	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E3S72_RS06250	ENOG4105XZU	Preprotein translocase, subunit SecG
E3S72_RS06265	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E3S72_RS06280	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3S72_RS06310	ENOG4105CHW	UPF0052 protein
E3S72_RS06320	ENOG4105C3M	thioredoxin reductase
E3S72_RS06330	ENOG4108S4C	acetyltransferase
E3S72_RS06345	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E3S72_RS06350	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E3S72_RS06365	ENOG41068JE	domain protein
E3S72_RS06395	ENOG41081UC	Inherit from COG: Competence protein
E3S72_RS06410	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E3S72_RS06415	ENOG4105ESV	Glycosyl transferase, family 4
E3S72_RS06475	ENOG4108IPW	abc transporter atp-binding protein
E3S72_RS06480	ENOG4105CM4	permease protein
E3S72_RS06485	ENOG4105DHS	permease protein
E3S72_RS06495	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3S72_RS06500	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3S72_RS06520	ENOG4105DUX	Transporter
E3S72_RS06535	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
E3S72_RS06545	ENOG4105E90	ABC transporter
E3S72_RS06550	ENOG4108IJ8	ABC transporter
E3S72_RS06555	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E3S72_RS06560	ENOG4105C5H	ABC transporter
E3S72_RS06590	ENOG4105CRQ	synthase (Component I)
E3S72_RS06595	ENOG4105DDQ	anthranilate synthase
E3S72_RS06605	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
E3S72_RS06610	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E3S72_RS06640	ENOG4105CKK	Glycosyl transferase, family 2
E3S72_RS06650	ENOG4105C37	(CBS) domain
E3S72_RS06655	ENOG4105CE4	GlcNAc 6-P deacetylase
E3S72_RS06660	ENOG4105DM4	PTS System
E3S72_RS06665	ENOG4105DE4	1-phosphofructokinase
E3S72_RS06670	ENOG4105E98	transcriptional regulator DeoR family
E3S72_RS06675	ENOG4108Z66	YbaK ebsC protein
E3S72_RS06685	ENOG4105DP8	Major facilitator superfamily MFS_1
E3S72_RS06705	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E3S72_RS06710	ENOG4107QPK	)-transporter
E3S72_RS06720	ENOG4107QM2	Aldo Keto reductase
E3S72_RS06725	ENOG4105CKI	cobalamin synthesis protein
E3S72_RS06730	ENOG41083AI	transcriptional regulator), MarR family
E3S72_RS06735	ENOG4108JJ8	(ABC) transporter
E3S72_RS06740	ENOG4108JJ9	ABC, transporter
E3S72_RS06760	ENOG4108URH	decarboxylase
E3S72_RS06765	ENOG4108YYQ	gCN5-related N-acetyltransferase
E3S72_RS06790	ENOG4105SXS	Protein of unknown function (DUF456)
E3S72_RS06795	ENOG4105S8Q	sugar efflux transporter
E3S72_RS06830	ENOG4105ID8	Transcriptional regulator, ARAC family
E3S72_RS06840	ENOG4105VRS	hydrolase family 18
E3S72_RS06845	ENOG4105CJ3	phosphate transporter
E3S72_RS06850	ENOG4107GRR	phosphate transport regulator
E3S72_RS06860	ENOG4105C19	ABC transporter
E3S72_RS06895	ENOG4108K88	Membrane
E3S72_RS06905	ENOG4105VDH	Dihydroxyacetone kinase
E3S72_RS06915	ENOG4105CMT	Dihydroxyacetone kinase
E3S72_RS06920	ENOG4105EHG	Permease protein
E3S72_RS06925	ENOG4105DQ5	transport system permease protein
E3S72_RS06930	ENOG4105E0A	ABC, transporter
E3S72_RS06935	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
E3S72_RS06950	ENOG4105BZ1	(ABC) transporter
E3S72_RS06960	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
E3S72_RS06980	ENOG4105EY8	ABC transporter
E3S72_RS06985	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
E3S72_RS06995	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
E3S72_RS07000	ENOG4105DIK	(ABC) transporter
E3S72_RS07005	ENOG4105CC5	ABC transporter
E3S72_RS07010	ENOG4105DSE	periplasmic solute binding protein
E3S72_RS07020	ENOG4105EEQ	Na H antiporter
E3S72_RS07060	ENOG4105E71	FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off
E3S72_RS07100	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
E3S72_RS07110	ENOG4108IU2	vtamin B12-transporter permease
E3S72_RS07115	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
E3S72_RS07145	ENOG4108XFG	YwhD family
E3S72_RS07150	ENOG4105DCI	Phosphohydrolase
E3S72_RS07160	ENOG4108WS4	fmn reductase
E3S72_RS07165	ENOG4105CPC	Aldo Keto reductase
E3S72_RS07200	ENOG4107QN2	dihydrolipoyl dehydrogenase
E3S72_RS07220	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E3S72_RS07225	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
E3S72_RS07230	ENOG4108IJ2	phosphate acetyltransferase
E3S72_RS07270	ENOG4105DWF	phosphomethylpyrimidine kinase
E3S72_RS07315	ENOG4108VA3	3-hexulose-6-phosphate synthase
E3S72_RS07330	ENOG4107YEI	lmbE family
E3S72_RS07355	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
E3S72_RS07360	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
E3S72_RS07370	ENOG410667J	hydrolase
E3S72_RS07375	ENOG4108Z6B	deaminase
E3S72_RS07385	ENOG4105ZMH	deoxynucleoside kinase
E3S72_RS07390	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E3S72_RS07395	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E3S72_RS07415	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E3S72_RS07450	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3S72_RS07460	ENOG4107Y49	methyltransferase
E3S72_RS07490	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E3S72_RS07495	ENOG410683Z	Preprotein translocase SecE subunit
E3S72_RS07515	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E3S72_RS07520	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3S72_RS07540	ENOG4105CTP	PilT protein domain protein
E3S72_RS07545	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E3S72_RS07560	ENOG4108Z0C	Uvrb UvrC protein
E3S72_RS07570	ENOG4105D9N	nucleoside
E3S72_RS07585	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E3S72_RS07680	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3S72_RS07685	ENOG4105KRF	dihydroneopterin aldolase
E3S72_RS07690	ENOG4105EEI	dihydropteroate synthase
E3S72_RS07695	ENOG4105C6T	cysteine synthase
E3S72_RS07705	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E3S72_RS07710	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E3S72_RS07715	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E3S72_RS07720	ENOG41060GV	RNA binding s1 domain protein
E3S72_RS07730	ENOG41082I2	s4 domain protein
E3S72_RS07735	ENOG4108IY2	MazG family
E3S72_RS07745	ENOG4108JA2	transcriptioN-repair coupling factor
E3S72_RS07760	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E3S72_RS07765	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E3S72_RS07780	ENOG4105KME	endoribonuclease L-psp
E3S72_RS07785	ENOG4105DFT	pur operon repressor
E3S72_RS07795	ENOG4105W42	Veg protein
E3S72_RS07805	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
E3S72_RS07810	ENOG4105F8V	Hydrolase, tatD family
E3S72_RS07815	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E3S72_RS07820	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E3S72_RS07830	ENOG41060K3	Methyltransferase
E3S72_RS07840	ENOG4105MA4	psp1 domain protein
E3S72_RS07845	ENOG4105FA2	dna polymerase iii
E3S72_RS07850	ENOG4105X0R	protein from nitrogen regulatory protein P-II
E3S72_RS07860	ENOG4105CXN	decarboxylase
E3S72_RS07890	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E3S72_RS07895	ENOG4105C6E	dna polymerase iii
E3S72_RS07915	ENOG4107414	GntR family transcriptional regulator
E3S72_RS07920	ENOG4105CG3	alpha amylase, catalytic region
E3S72_RS07925	ENOG4105C5Y	PTS System
E3S72_RS07935	ENOG4105BZ8	glutamate synthase
E3S72_RS07940	ENOG4105CBC	glutamate synthase
E3S72_RS07945	ENOG4105C5Q	Transcriptional regulator
E3S72_RS07980	ENOG4105D01	(LipO)protein
E3S72_RS07985	ENOG4108UMI	ABC transporter, permease
E3S72_RS07990	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E3S72_RS07995	ENOG4105C28	cystathionine
E3S72_RS08005	ENOG4105C8J	)-transporter
E3S72_RS08025	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
E3S72_RS08035	ENOG4108TWJ	NADH dehydrogenase subunit 5
E3S72_RS08060	ENOG4105CKI	cobalamin synthesis protein
E3S72_RS08220	ENOG4105KA3	membrAne
E3S72_RS08255	ENOG4105C2W	permease
E3S72_RS08285	ENOG4107R6U	sodium dicarboxylate symporter
E3S72_RS08290	ENOG4108DBC	nitroreductase
E3S72_RS08300	ENOG4108JU3	Alkyl hydroperoxide reductase
E3S72_RS08370	ENOG4108UUM	single-stranded DNA-binding protein
E3S72_RS08385	ENOG4105C3G	gtp-binding protein
E3S72_RS08390	ENOG4105VDK	protein, conserved in bacteria
E3S72_RS08395	ENOG4105D8X	mechanosensitive ion channel
E3S72_RS08400	ENOG4105FA0	parb-like partition protein
E3S72_RS08405	ENOG4105C28	cystathionine
E3S72_RS08410	ENOG4105C28	cystathionine
E3S72_RS08430	ENOG4105CHU	acetyl-coa acetyltransferase
E3S72_RS08445	ENOG4105CJ1	ABC, transporter
E3S72_RS08455	ENOG4105VZ8	Transcriptional regulator
E3S72_RS08465	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E3S72_RS08470	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E3S72_RS08475	ENOG4107SJW	iron permease, FTR1
E3S72_RS08480	ENOG4105DBE	peroxidase
E3S72_RS08485	ENOG410650H	(LipO)protein
E3S72_RS08500	ENOG4107V0Z	fmn reductase
E3S72_RS08515	ENOG4105CXY	transporter
E3S72_RS08525	ENOG4105C3S	Mate efflux family protein
E3S72_RS08535	ENOG4105CID	antiterminator
E3S72_RS08540	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
E3S72_RS08550	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
E3S72_RS08555	ENOG4105CMR	udp-glucose 4-epimerase
E3S72_RS08570	ENOG4108UVJ	appr-1-p processing domain protein
E3S72_RS08580	ENOG4105DEN	Luciferase family
E3S72_RS08615	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
E3S72_RS08665	ENOG4108FKH	Transglycosylase SLT domain
E3S72_RS08715	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E3S72_RS08935	ENOG4105DWD	nucleoside recognition domain protein
E3S72_RS08945	ENOG4106KNT	transcriptional regulator
E3S72_RS08950	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
E3S72_RS08960	ENOG4107RJ1	sodium solute
E3S72_RS08965	ENOG4105D9N	nucleoside
E3S72_RS08995	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
E3S72_RS09000	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
E3S72_RS09095	ENOG4105EC2	ftsk spoIIIe
E3S72_RS09105	ENOG4106GSS	Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity)
E3S72_RS09115	ENOG4106PAW	secretion accessory protein EsaA YueB
E3S72_RS09125	ENOG4105VRS	hydrolase family 18
E3S72_RS09145	ENOG4105DA5	(ABC) transporter
E3S72_RS09150	ENOG4105DR5	peptidase
E3S72_RS09180	ENOG4105EV1	Ribose uptake protein RbsU
E3S72_RS09200	ENOG4105DVA	methyltransferase
E3S72_RS09205	ENOG4105CS2	ec 3.2.1.21
E3S72_RS09210	ENOG4105CI1	PTS System
E3S72_RS09250	ENOG4107RZX	Teichoic acid biosynthesis protein
E3S72_RS09255	ENOG4105EJJ	Dehydrogenase
E3S72_RS09265	ENOG4107SJB	teichoic acid biosynthesis
E3S72_RS09270	ENOG4107RZX	Teichoic acid biosynthesis protein
E3S72_RS09275	ENOG4105EJJ	Dehydrogenase
E3S72_RS09280	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E3S72_RS09285	ENOG4105CPQ	Dehydrogenase
E3S72_RS09295	ENOG4105CPQ	Dehydrogenase
E3S72_RS09300	ENOG4105DT3	PTS system, galactitol-specific IIc component
E3S72_RS09305	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
E3S72_RS09325	ENOG4105DU0	nucleoside hydrolase
E3S72_RS09330	ENOG4105CI1	PTS System
E3S72_RS09355	ENOG4105K78	MarR family Transcriptional regulator
E3S72_RS09360	ENOG4107RRN	ABC transporter substrate-binding protein
E3S72_RS09370	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
E3S72_RS09375	ENOG4105CEY	Amp-dependent synthetase and ligase
E3S72_RS09380	ENOG4105C1G	acyl-Coa dehydrogenase
E3S72_RS09385	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3S72_RS09390	ENOG4105CHU	acetyl-coa acetyltransferase
E3S72_RS09440	ENOG4105CXY	transporter
E3S72_RS09445	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
E3S72_RS09455	ENOG4105CK5	oxidoreductase
E3S72_RS09465	ENOG4105EG2	ABC transporter, permease
E3S72_RS09500	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E3S72_RS09510	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3S72_RS09515	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E3S72_RS09530	ENOG4105DA5	(ABC) transporter
E3S72_RS09550	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E3S72_RS09555	ENOG4105C19	ABC transporter
E3S72_RS09570	ENOG4105DZR	Type I site-specific deoxyribonuclease
E3S72_RS09580	ENOG4105QEK	Transcriptional regulator
E3S72_RS09610	ENOG4107RA9	decarboxylase
E3S72_RS09615	ENOG4105D3W	isochorismatase
E3S72_RS09620	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E3S72_RS09625	ENOG4105C8Y	Acetylornithine aminotransferase
E3S72_RS09635	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E3S72_RS09670	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
E3S72_RS09675	ENOG4105C1G	acyl-Coa dehydrogenase
E3S72_RS09705	ENOG4105PGM	cation diffusion facilitator family transporter
E3S72_RS09710	ENOG4105C26	Dehydrogenase
E3S72_RS09715	ENOG4105WD1	Membrane
E3S72_RS09725	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E3S72_RS09740	ENOG4105D3Q	Sugar transferase
E3S72_RS09770	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E3S72_RS09780	ENOG4105C5E	polysaccharide biosynthesis protein
E3S72_RS09805	ENOG4108EKI	Dehydrogenase
E3S72_RS09820	ENOG4105CGH	5'-nucleotidase
E3S72_RS09855	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E3S72_RS09860	ENOG4108J8C	transporter major facilitator family protein
E3S72_RS09865	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
E3S72_RS09895	ENOG4105CPK	Glycosyl transferase (Group 1
E3S72_RS09905	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E3S72_RS09915	ENOG4105CHR	reductase
E3S72_RS09925	ENOG41067FT	ParB-like nuclease domain
E3S72_RS09930	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E3S72_RS09940	ENOG4105DUU	IucA IucC family protein
E3S72_RS09945	ENOG4105DBM	Siderophore biosynthesis protein
E3S72_RS09950	ENOG4105C6X	Major Facilitator
E3S72_RS09955	ENOG4105DJU	Siderophore biosynthesis protein
E3S72_RS09960	ENOG4105CIF	Ornithine Cyclodeaminase
E3S72_RS09970	ENOG4108MES	Periplasmic binding protein
E3S72_RS09975	ENOG4105DQ5	transport system permease protein
E3S72_RS09980	ENOG4108IHU	transport system permease protein
E3S72_RS10010	ENOG4107Y9U	Membrane
E3S72_RS10015	ENOG4105CCI	Myosin-Cross-Reactive Antigen
E3S72_RS10025	ENOG4105C57	major facilitator superfamily
E3S72_RS10065	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
E3S72_RS10095	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E3S72_RS10110	ENOG4105C5X	domain protein
E3S72_RS10115	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
E3S72_RS10120	ENOG4105XTG	Pfam:DUF156
E3S72_RS10125	ENOG41087NI	Sulfite exporter TauE/SafE
E3S72_RS10160	ENOG4105CGH	5'-nucleotidase
E3S72_RS10165	ENOG4105Q2H	domain protein
E3S72_RS10200	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E3S72_RS10205	ENOG4105CDU	Replicative dna helicase
E3S72_RS10215	ENOG4105BZR	domain protein
E3S72_RS10225	ENOG4105DWV	Homoserine O-trans-acetylase
E3S72_RS10250	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E3S72_RS10260	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3S72_RS10270	ENOG410848D	S4 domain protein YaaA
E3S72_RS10275	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E3S72_RS10310	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
E3S72_RS10345	ENOG4105C19	ABC transporter
E3S72_RS10360	ENOG4105D9G	High-affinity
E3S72_RS10370	ENOG4105FR1	rard protein
E3S72_RS10375	ENOG4107QPK	)-transporter
E3S72_RS10455	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E3S72_RS10460	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E3S72_RS10470	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E3S72_RS10485	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E3S72_RS10495	ENOG4105J1V	Triacylglycerol lipase
E3S72_RS10505	ENOG4107UVV	polysaccharide deacetylase
E3S72_RS10515	ENOG4107QJZ	Glycosyl transferase, family 2
E3S72_RS10520	ENOG4108IG5	Transcriptional regulator
E3S72_RS10525	ENOG4105HTX	biosynthesis protein
E3S72_RS10545	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E3S72_RS10550	ENOG4107XC4	flavin reductase domain protein, FMN-binding
E3S72_RS10570	ENOG4105EW6	flavin reductase domain protein, FMN-binding
E3S72_RS10585	ENOG4108XJK	accessory Sec system protein Asp1
E3S72_RS10590	ENOG41089G2	accessory Sec system protein Asp2
E3S72_RS10595	ENOG4106E62	Accessory Sec system protein Asp3
E3S72_RS10620	ENOG4105WQI	isochorismatase
E3S72_RS10625	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
E3S72_RS10635	ENOG4105DG6	mannose-6-phosphate isomerase
E3S72_RS10640	ENOG4105DM4	PTS System
E3S72_RS10680	ENOG4105DBV	ornithine carbamoyltransferase
E3S72_RS10690	ENOG4105C5B	carbamate kinase
E3S72_RS10700	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
E3S72_RS10710	ENOG4108U05	Transcriptional regulator
E3S72_RS10720	ENOG4105G6Z	alkaline phosphatase
E3S72_RS10770	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E3S72_RS10775	ENOG4108Z73	Siroheme synthase
E3S72_RS10785	ENOG4105D4T	Citrate transporter
E3S72_RS10790	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
E3S72_RS10795	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
E3S72_RS10810	ENOG4105C94	Transporter
E3S72_RS10815	ENOG4105TRT	Transcriptional regulator
E3S72_RS10825	ENOG4105C26	Dehydrogenase
E3S72_RS10845	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E3S72_RS10855	ENOG4105DWT	malate dehydrogenase (quinone)
E3S72_RS10870	ENOG4108JPW	Aminotransferase
E3S72_RS10875	ENOG4105CUB	amino acid
E3S72_RS10885	ENOG4107FQX	Alpha-acetolactate decarboxylase
E3S72_RS10890	ENOG4108NKJ	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E3S72_RS10950	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E3S72_RS10955	ENOG4105FGM	Fructosamine kinase
E3S72_RS10975	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
E3S72_RS11000	ENOG4105CHR	reductase
E3S72_RS11060	ENOG4105EXC	Acyl-transferase
E3S72_RS11065	ENOG41068JE	domain protein
E3S72_RS11075	ENOG4105EWK	phytoene
E3S72_RS11080	ENOG41076QQ	Glycosyl transferase, family 2
E3S72_RS11085	ENOG4105FE1	phytoene synthase
E3S72_RS11140	ENOG4105EYF	MMPL domain protein
E3S72_RS11150	ENOG4105CE1	Ferrous iron transport protein b
E3S72_RS11160	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3S72_RS11165	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E3S72_RS11170	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
E3S72_RS11180	ENOG41068JE	domain protein
E3S72_RS11190	ENOG4105CMU	LysR family (Transcriptional regulator
E3S72_RS11200	ENOG41067MG	lrgb family
E3S72_RS11230	ENOG4108UZ3	Transporter
E3S72_RS11250	ENOG4105EJQ	L-serine dehydratase
E3S72_RS11265	ENOG4108Z7F	N-acetyltransferase
E3S72_RS11270	ENOG4108Z6X	(sortase) family
E3S72_RS11275	ENOG4106KKU	
E3S72_RS11280	ENOG4108Z15	abc transporter atp-binding protein
E3S72_RS11285	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
E3S72_RS11290	ENOG4105C5I	Dehydrogenase
E3S72_RS11300	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
E3S72_RS11310	ENOG41090MY	MarR family Transcriptional regulator
E3S72_RS11320	ENOG4105FBA	Phospholipase Carboxylesterase
E3S72_RS11340	ENOG4105CJ1	ABC, transporter
E3S72_RS11350	ENOG4107T5V	SNARE associated Golgi
E3S72_RS11355	ENOG4105DJB	Major Facilitator Superfamily
E3S72_RS11365	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
E3S72_RS11380	ENOG4105G3Z	GntR family transcriptional regulator
E3S72_RS11385	ENOG4105CMG	Carbohydrate kinase
E3S72_RS11455	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
E3S72_RS11460	ENOG4105M6F	mutator MutT protein
E3S72_RS11550	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E3S72_RS11555	ENOG4105CFC	Transporter
E3S72_RS11560	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E3S72_RS11565	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
E3S72_RS11620	ENOG4105CBC	glutamate synthase
E3S72_RS11625	ENOG4105PQ4	(LipO)protein
E3S72_RS11640	ENOG4105CN9	Peptidase m42 family protein
E3S72_RS11645	ENOG41083J0	(ABC) transporter
E3S72_RS11650	ENOG4105C4B	ABC transporter, permease
E3S72_RS11655	ENOG4105F27	Major Facilitator
E3S72_RS11660	ENOG4105EBR	Carboxylesterase
E3S72_RS11665	ENOG4107QTZ	amino acid
E3S72_RS11670	ENOG4105CZ9	Domain of unknown function (DU1801)
E3S72_RS11690	ENOG4105E90	ABC transporter
E3S72_RS11700	ENOG4105R40	Glycine betaine carnitine choline
E3S72_RS11705	ENOG4105C57	major facilitator superfamily
E3S72_RS11710	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E3S72_RS11720	ENOG4105ED2	Beta-lactamase
E3S72_RS11725	ENOG4105C0X	amino acid
E3S72_RS11730	ENOG4105EEQ	Na H antiporter
E3S72_RS11735	ENOG4105C85	amino acid
E3S72_RS11755	ENOG4105C2C	drug resistance transporter, Bcr CflA
E3S72_RS11765	ENOG4105BZW	Glycerate kinase
E3S72_RS11785	ENOG4105BZ1	(ABC) transporter
E3S72_RS11795	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
E3S72_RS11800	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E3S72_RS11810	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E3S72_RS11825	ENOG4106XHW	Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity)
E3S72_RS11870	ENOG4105EAB	amino acid AbC transporter
E3S72_RS11875	ENOG4105DRP	amino acid AbC transporter
E3S72_RS11880	ENOG4105CDA	abc transporter atp-binding protein
E3S72_RS11920	ENOG4105DSE	periplasmic solute binding protein
E3S72_RS11935	ENOG4105TMB	Formate nitrite transporter
E3S72_RS11940	ENOG4108XSB	acetyltransferase, (GNAT) family
E3S72_RS11950	ENOG4108IFG	nitrite reductase, (NAD(P)H)
E3S72_RS11955	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
E3S72_RS11960	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E3S72_RS11970	ENOG4108IUE	nitrate reductase beta subunit
E3S72_RS12000	ENOG4107TXC	Transcriptional regulator
E3S72_RS12040	ENOG410606W	general stress protein
E3S72_RS12070	ENOG4105ECB	domain protein
E3S72_RS12120	ENOG4105DWT	malate dehydrogenase (quinone)
E3S72_RS12150	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E3S72_RS12160	ENOG41062A4	Transcriptional regulator
E3S72_RS12185	ENOG4105CW7	secretion protein, HlyD family
E3S72_RS12190	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E3S72_RS12215	ENOG4105D7N	magnesium and cobalt transport protein CorA
E3S72_RS12225	ENOG4105D6U	Sodium Glutamate Symporter
E3S72_RS12235	ENOG4105KAF	membrAne
E3S72_RS12240	ENOG4108IUX	(ABC) transporter
E3S72_RS12245	ENOG4105RHA	ABC transporter, permease
E3S72_RS12270	ENOG4105E66	phosphoriboisomerase A
E3S72_RS12290	ENOG4105C5Q	Transcriptional regulator
E3S72_RS12295	ENOG4105CGP	Urocanate hydratase
E3S72_RS12305	ENOG4105CH2	amidohydrolase
E3S72_RS12310	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E3S72_RS12330	ENOG4108Q3X	Transcriptional regulator
E3S72_RS12335	ENOG4105CI1	PTS System
E3S72_RS12345	ENOG4105C09	Bile acid
E3S72_RS12350	ENOG4107YBY	Hydrolase
E3S72_RS12420	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
E3S72_RS12450	ENOG4105DFD	Na H antiporter
E3S72_RS12460	ENOG41068JE	domain protein
E3S72_RS12525	ENOG4105FDT	acyl-CoA dehydrogenase
E3S72_RS12540	ENOG4107ZYJ	bioY protein
E3S72_RS12555	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E3S72_RS12560	ENOG4105E0C	molybdate abc transporter
E3S72_RS12565	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E3S72_RS12570	ENOG4105D06	uba thif-type nad fad binding protein
E3S72_RS12575	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
E3S72_RS12585	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E3S72_RS12590	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
E3S72_RS12595	ENOG4108ZAF	Molybdopterin
E3S72_RS12645	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
E3S72_RS12675	ENOG4105CSC	Glucose uptake protein
E3S72_RS12695	ENOG4105C7N	Xanthine uracil vitamin C permease
E3S72_RS12810	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E3S72_RS12815	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E3S72_RS12850	ENOG4108JJB	ABC transporter
E3S72_RS12905	ENOG4107RRE	RNA-directed DNA polymerase
E3S72_RS12920	ENOG4107FQX	Alpha-acetolactate decarboxylase
E3S72_RS12940	ENOG4106AM8	polysaccharide lyase family 8
E3S72_RS12950	ENOG4105VUF	Transcriptional regulator
E3S72_RS12970	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E3S72_RS12975	ENOG4105E98	transcriptional regulator DeoR family
E3S72_RS13000	ENOG4105VCP	PTS System
E3S72_RS13005	ENOG4105CK1	PTS System
E3S72_RS13020	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E3S72_RS13025	ENOG4105CIS	alcohol dehydrogenase
E3S72_RS13030	ENOG4105C94	Transporter
E3S72_RS13055	ENOG4107SFI	Major Facilitator superfamily
E3S72_RS13065	ENOG4106M28	alanine racemase domain protein
E3S72_RS13075	ENOG4108HUF	Transporter
E3S72_RS13080	ENOG4105DQ5	transport system permease protein
E3S72_RS13085	ENOG4108U1V	ABC transporter, permease
E3S72_RS13090	ENOG4105DWD	nucleoside recognition domain protein
E3S72_RS13100	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
E3S72_RS13105	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
E3S72_RS13110	ENOG4108UT2	hemolysin iii
E3S72_RS13130	ENOG4105D1F	ATP-binding protein
E3S72_RS13185	ENOG4105CYW	agmatinase
E3S72_RS13190	ENOG4105C8B	TIGR00159 family
E3S72_RS13215	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
E3S72_RS13220	ENOG4105ETD	TRANSCRIPTIONal
E3S72_RS13225	ENOG4105CTS	PTS system mannitol-specific
E3S72_RS13230	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E3S72_RS13235	ENOG4105DKW	ABC transporter
E3S72_RS13260	ENOG4105PGM	cation diffusion facilitator family transporter
E3S72_RS13275	ENOG4105DG6	mannose-6-phosphate isomerase
E3S72_RS13295	ENOG4108RMU	ferritin dps family protein
E3S72_RS13300	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
E3S72_RS13305	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E3S72_RS13310	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
E3S72_RS13340	ENOG4105HNY	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E3S72_RS13365	ENOG4105D2N	Aldolase
E3S72_RS13385	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E3S72_RS13395	ENOG4107104	thymidine kinase
E3S72_RS13405	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E3S72_RS13410	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E3S72_RS13435	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E3S72_RS13500	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E3S72_RS13530	ENOG4105DWF	phosphomethylpyrimidine kinase
E3S72_RS13570	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E3S72_RS13575	ENOG4105VPX	protein, conserved in bacteria
E3S72_RS13600	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
E3S72_RS13615	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E3S72_RS13620	ENOG4105C08	Histidine kinase
E3S72_RS13630	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E3S72_RS13635	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E3S72_RS13640	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
E3S72_RS13650	ENOG4105CKV	Membrane
E3S72_RS13665	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E3S72_RS13680	ENOG4107SGM	protein serine threonine phosphatase
E3S72_RS13685	ENOG4105WN5	stage II sporulation protein
E3S72_RS13750	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E3S72_RS13770	ENOG4105C7K	acetolactate synthase
E3S72_RS13785	ENOG4105K8N	protein family UPF0079, ATPase
E3S72_RS13790	ENOG41072GX	Peptidase M22 Glycoprotease
E3S72_RS13795	ENOG410801F	ribosomal-protein-alanine acetyltransferase
E3S72_RS13805	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E3S72_RS13815	ENOG4105C5H	ABC transporter
E3S72_RS13825	ENOG4105CUC	YeeE YedE family protein
E3S72_RS13835	ENOG4105BZU	Histidine kinase
E3S72_RS13860	ENOG4108WCX	response regulator
E3S72_RS13915	ENOG4105CZN	Potassium uptake protein
E3S72_RS13970	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)