locus-tag	class	description
E3S73_RS00020	COG0740	serine-type endopeptidase activity
E3S73_RS00070	COG0739	heme binding
E3S73_RS00115	COG1388	LysM domain
E3S73_RS00115	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S73_RS00125	COG1388	LysM domain
E3S73_RS00125	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S73_RS00175	COG1725	Transcriptional regulator
E3S73_RS00190	COG1131	(ABC) transporter
E3S73_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
E3S73_RS00255	COG1335	isochorismatase
E3S73_RS00275	COG0077	Prephenate dehydratase
E3S73_RS00285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3S73_RS00320	COG4496	protein, YerC YecD
E3S73_RS00340	COG4851	CamS sex pheromone cAM373 precursor
E3S73_RS00455	COG1295	ribonuclease BN
E3S73_RS00475	COG2309	aminopeptidase activity
E3S73_RS00480	COG1607	acyl-coa hydrolase
E3S73_RS00485	COG0535	radical SAM domain protein
E3S73_RS00490	COG4974	Belongs to the 'phage' integrase family
E3S73_RS00515	COG1396	sequence-specific DNA binding
E3S73_RS00585	COG1484	DNA-dependent DNA replication
E3S73_RS00675	COG1783	phage Terminase large subunit
E3S73_RS00805	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S73_RS00805	COG1388	LysM domain
E3S73_RS00855	COG1388	LysM domain
E3S73_RS00855	COG1134	teichoic acid transport
E3S73_RS00865	COG1988	membrane-bound metal-dependent
E3S73_RS00870	COG1194	a g-specific adenine glycosylase
E3S73_RS00885	COG4129	membrane
E3S73_RS00895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3S73_RS00900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S73_RS01065	COG0765	amino acid transport
E3S73_RS01070	COG1126	abc transporter atp-binding protein
E3S73_RS01075	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3S73_RS01105	COG0564	pseudouridine synthase activity
E3S73_RS01110	COG4585	Histidine kinase
E3S73_RS01110	COG2203	Gaf domain
E3S73_RS01115	COG2197	response regulator
E3S73_RS01135	COG0420	3'-5' exonuclease activity
E3S73_RS01165	COG0537	adenosine 5'-monophosphoramidase activity
E3S73_RS01170	COG1131	(ABC) transporter
E3S73_RS01380	COG5492	domain, Protein
E3S73_RS01470	COG2816	NAD+ diphosphatase activity
E3S73_RS01495	COG0656	L-ascorbic acid biosynthetic process
E3S73_RS01505	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E3S73_RS01515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3S73_RS01550	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S73_RS01550	COG4193	domain, Protein
E3S73_RS01550	COG3266	domain, Protein
E3S73_RS01570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S73_RS01570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S73_RS01600	COG2267	carboxylic ester hydrolase activity
E3S73_RS01605	COG1846	Transcriptional regulator
E3S73_RS01610	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3S73_RS01615	COG1242	4 iron, 4 sulfur cluster binding
E3S73_RS01620	COG2814	Major facilitator Superfamily
E3S73_RS01640	COG2081	HI0933 family
E3S73_RS01645	COG2244	polysaccharide biosynthetic process
E3S73_RS01650	COG1187	pseudouridine synthase activity
E3S73_RS01670	COG0510	thiamine kinase activity
E3S73_RS01680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S73_RS01690	COG1363	Peptidase, m42
E3S73_RS01695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S73_RS01705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3S73_RS01710	COG1674	ftsk spoiiie
E3S73_RS01735	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E3S73_RS01735	COG1605	Chorismate mutase
E3S73_RS01755	COG0454	-acetyltransferase
E3S73_RS01760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S73_RS01790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3S73_RS01795	COG0204	Acyl-transferase
E3S73_RS01800	COG1263	PTS System
E3S73_RS01800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S73_RS01815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S73_RS01820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E3S73_RS01825	COG1764	response to oxidative stress
E3S73_RS01830	COG0584	glycerophosphoryl diester phosphodiesterase
E3S73_RS01845	COG1956	GAF domain-containing protein
E3S73_RS01860	COG1104	cysteine desulfurase activity
E3S73_RS01870	COG0730	response to heat
E3S73_RS01880	COG0827	DNA restriction-modification system
E3S73_RS01920	COG4109	DRTGG domain
E3S73_RS01925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3S73_RS01935	COG0281	malic enzyme
E3S73_RS01960	COG1113	amino acid transport
E3S73_RS01965	COG0372	Belongs to the citrate synthase family
E3S73_RS01975	COG0745	RESPONSE REGULATOR receiver
E3S73_RS01980	COG5002	protein histidine kinase activity
E3S73_RS01990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S73_RS01990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S73_RS01995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3S73_RS02020	COG1484	DNA-dependent DNA replication
E3S73_RS02035	COG0833	amino acid
E3S73_RS02055	COG4112	unkown
E3S73_RS02090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3S73_RS02105	COG0113	porphobilinogen synthase activity
E3S73_RS02125	COG2818	Glycosylase
E3S73_RS02135	COG0285	dihydrofolate synthase activity
E3S73_RS02140	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E3S73_RS02185	COG2868	ribosomal protein
E3S73_RS02225	COG1862	Preprotein translocase
E3S73_RS02230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S73_RS02230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S73_RS02235	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E3S73_RS02235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3S73_RS02280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3S73_RS02285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3S73_RS02290	COG1959	2 iron, 2 sulfur cluster binding
E3S73_RS02305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S73_RS02310	COG1104	cysteine desulfurase activity
E3S73_RS02325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3S73_RS02375	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3S73_RS02380	COG1984	allophanate hydrolase subunit 2
E3S73_RS02385	COG0511	ligase activity, forming carbon-carbon bonds
E3S73_RS02390	COG0439	Biotin carboxylase
E3S73_RS02400	COG1914	H( )-stimulated, divalent metal cation uptake system
E3S73_RS02405	COG3177	Filamentation induced by cAMP protein fic
E3S73_RS02425	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E3S73_RS02430	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E3S73_RS02440	COG1534	Rna-binding protein
E3S73_RS02450	COG1713	HD superfamily hydrolase involved in NAD metabolism
E3S73_RS02455	COG0799	negative regulation of ribosome biogenesis
E3S73_RS02460	COG2226	methyltransferase
E3S73_RS02470	COG2131	deaminase
E3S73_RS02475	COG0658	competence protein
E3S73_RS02475	COG2333	competence protein COMEC
E3S73_RS02480	COG1466	dna polymerase III delta subunit
E3S73_RS02495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3S73_RS02525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3S73_RS02530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3S73_RS02540	COG1030	water channel activity
E3S73_RS02555	COG1702	phosphate starvation-inducible protein PhoH
E3S73_RS02570	COG0295	cytidine deaminase activity
E3S73_RS02590	COG0517	IMP dehydrogenase activity
E3S73_RS02605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3S73_RS02610	COG2384	SAM-dependent methyltransferase
E3S73_RS02620	COG0513	Belongs to the DEAD box helicase family
E3S73_RS02630	COG1121	(ABC) transporter
E3S73_RS02635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S73_RS02640	COG0735	belongs to the Fur family
E3S73_RS02660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3S73_RS02670	COG4483	Protein conserved in bacteria
E3S73_RS02675	COG1940	carbohydrate kinase activity
E3S73_RS02680	COG0011	TIGRFAM Protein of
E3S73_RS02685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S73_RS02690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3S73_RS02705	COG4537	Required for transformation and DNA binding
E3S73_RS02750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3S73_RS02755	COG0095	Lipoate-protein ligase
E3S73_RS02770	COG0006	proline dipeptidase activity
E3S73_RS02780	COG0511	ligase activity, forming carbon-carbon bonds
E3S73_RS02785	COG0439	Biotin carboxylase
E3S73_RS02790	COG1302	Protein conserved in bacteria
E3S73_RS02820	COG0497	DNA recombination
E3S73_RS02825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S73_RS02830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E3S73_RS02835	COG0022	dehydrogenase e1 component
E3S73_RS02840	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3S73_RS02850	COG4129	membrane
E3S73_RS02860	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3S73_RS02890	COG1609	Transcriptional regulator
E3S73_RS02895	COG0366	Alpha amylase catalytic
E3S73_RS02905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3S73_RS02920	COG4221	oxidoreductase activity
E3S73_RS02930	COG0667	Aldo Keto reductase
E3S73_RS02935	COG0494	nUDIX hydrolase
E3S73_RS02940	COG0735	belongs to the Fur family
E3S73_RS02965	COG1187	pseudouridine synthase activity
E3S73_RS02970	COG0745	RESPONSE REGULATOR receiver
E3S73_RS03020	COG1141	Ferredoxin
E3S73_RS03030	COG0514	ATP-dependent DNA helicase (RecQ)
E3S73_RS03045	COG0492	ferredoxin-NADP+ reductase activity
E3S73_RS03100	COG0142	geranyltranstransferase activity
E3S73_RS03135	COG4347	Protein of unknown function (DUF1405)
E3S73_RS03140	COG2738	Putative neutral zinc metallopeptidase
E3S73_RS03145	COG1694	Mazg nucleotide pyrophosphohydrolase
E3S73_RS03150	COG0438	transferase activity, transferring glycosyl groups
E3S73_RS03175	COG3935	DnaD domain protein
E3S73_RS03180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3S73_RS03190	COG4499	WXG100 protein secretion system (Wss), protein YukC
E3S73_RS03190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3S73_RS03220	COG0116	Belongs to the methyltransferase superfamily
E3S73_RS03235	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3S73_RS03240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S73_RS03255	COG0531	amino acid
E3S73_RS03275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3S73_RS03335	COG2826	transposase and inactivated derivatives, IS30 family
E3S73_RS03355	COG0671	phosphoesterase, PA-phosphatase related
E3S73_RS03405	COG4548	von Willebrand factor, type A
E3S73_RS03475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3S73_RS03480	COG0527	aspartate kinase activity
E3S73_RS03485	COG0488	(ABC) transporter
E3S73_RS03500	COG0573	inorganic phosphate transmembrane transporter activity
E3S73_RS03505	COG0581	inorganic phosphate transmembrane transporter activity
E3S73_RS03515	COG0704	Plays a role in the regulation of phosphate uptake
E3S73_RS03565	COG2348	transferase activity, transferring amino-acyl groups
E3S73_RS03600	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S73_RS03605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S73_RS03610	COG1363	Peptidase, m42
E3S73_RS03620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3S73_RS03635	COG1316	TRANSCRIPTIONal
E3S73_RS03640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S73_RS03650	COG0628	permease
E3S73_RS03665	COG1115	amino acid carrier protein
E3S73_RS03675	COG0187	DNA topoisomerase II activity
E3S73_RS03690	COG0824	Thioesterase
E3S73_RS03700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S73_RS03720	COG4846	Membrane protein involved in cytochrome C biogenesis
E3S73_RS03785	COG0833	amino acid
E3S73_RS03810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3S73_RS03815	COG0460	homoserine dehydrogenase
E3S73_RS03820	COG0527	aspartate kinase activity
E3S73_RS03835	COG1525	nuclease
E3S73_RS03845	COG2197	response regulator
E3S73_RS03860	COG1131	(ABC) transporter
E3S73_RS03940	COG2826	transposase and inactivated derivatives, IS30 family
E3S73_RS03975	COG0789	Transcriptional regulator
E3S73_RS03980	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E3S73_RS03995	COG1923	regulation of RNA biosynthetic process
E3S73_RS04020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3S73_RS04025	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3S73_RS04060	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3S73_RS04065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3S73_RS04065	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3S73_RS04070	COG1692	metallophosphoesterase
E3S73_RS04090	COG1546	Belongs to the CinA family
E3S73_RS04090	COG1058	Belongs to the CinA family
E3S73_RS04110	COG0300	oxidoreductase activity
E3S73_RS04115	COG0612	Peptidase, M16
E3S73_RS04120	COG0612	Peptidase, M16
E3S73_RS04125	COG2188	Transcriptional regulator
E3S73_RS04150	COG0196	riboflavin kinase activity
E3S73_RS04175	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E3S73_RS04180	COG0195	Participates in both transcription termination and antitermination
E3S73_RS04280	COG2348	transferase activity, transferring amino-acyl groups
E3S73_RS04335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3S73_RS04345	COG0552	protein localization to endoplasmic reticulum
E3S73_RS04350	COG1196	nuclear chromosome segregation
E3S73_RS04395	COG1302	Protein conserved in bacteria
E3S73_RS04410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3S73_RS04425	COG0631	protein serine/threonine phosphatase activity
E3S73_RS04435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3S73_RS04435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3S73_RS04450	COG2314	TM2 domain
E3S73_RS04460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3S73_RS04465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3S73_RS04525	COG2233	PERMEase
E3S73_RS04535	COG0564	pseudouridine synthase activity
E3S73_RS04545	COG2514	catechol 2,3-dioxygenase activity
E3S73_RS04550	COG2826	transposase and inactivated derivatives, IS30 family
E3S73_RS04560	COG3599	regulation of cell shape
E3S73_RS04565	COG2302	S4 RNA-binding domain
E3S73_RS04570	COG0762	integral membrane protein
E3S73_RS04580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3S73_RS04590	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3S73_RS04620	COG4839	cell division protein FtsL
E3S73_RS04645	COG1011	Hydrolase
E3S73_RS04675	COG1288	antiporter activity
E3S73_RS04785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3S73_RS04790	COG1053	succinate dehydrogenase
E3S73_RS04795	COG2009	succinate dehydrogenase
E3S73_RS04820	COG1796	DNA polymerase
E3S73_RS04820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3S73_RS04850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3S73_RS04865	COG4509	Sortase family
E3S73_RS04920	COG0742	ribosomal rna small subunit methyltransferase
E3S73_RS04940	COG3679	Belongs to the UPF0342 family
E3S73_RS04945	COG2340	Cysteine-rich secretory protein family
E3S73_RS04965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3S73_RS04970	COG0772	Belongs to the SEDS family
E3S73_RS04980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E3S73_RS05000	COG0483	inositol monophosphate 1-phosphatase activity
E3S73_RS05025	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3S73_RS05030	COG1177	transmembrane transport
E3S73_RS05035	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3S73_RS05100	COG0569	domain protein
E3S73_RS05105	COG1294	oxidase, subunit
E3S73_RS05110	COG1271	oxidase subunit
E3S73_RS05135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3S73_RS05150	COG4721	ABC-type cobalt transport system, permease component
E3S73_RS05155	COG4172	Belongs to the ABC transporter superfamily
E3S73_RS05160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E3S73_RS05200	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3S73_RS05215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3S73_RS05260	COG1316	TRANSCRIPTIONal
E3S73_RS05290	COG3594	Acyltransferase
E3S73_RS05295	COG0436	Aminotransferase
E3S73_RS05320	COG2267	carboxylic ester hydrolase activity
E3S73_RS05330	COG1169	isochorismate synthase
E3S73_RS05340	COG1575	Belongs to the MenA family. Type 1 subfamily
E3S73_RS05345	COG0456	acetyltransferase
E3S73_RS05350	COG2314	TM2 domain
E3S73_RS05360	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S73_RS05420	COG4873	Protein conserved in bacteria
E3S73_RS05435	COG4903	ComK protein
E3S73_RS05450	COG0737	Belongs to the 5'-nucleotidase family
E3S73_RS05455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S73_RS05465	COG0861	Integral membrane protein TerC family
E3S73_RS05515	COG1115	amino acid carrier protein
E3S73_RS05520	COG0628	permease
E3S73_RS05530	COG0569	domain protein
E3S73_RS05530	COG0475	glutathione-regulated potassium exporter activity
E3S73_RS05535	COG2239	Acts as a magnesium transporter
E3S73_RS05540	COG0564	pseudouridine synthase activity
E3S73_RS05550	COG2357	RelA SpoT domain protein
E3S73_RS05565	COG2346	COG2346, Truncated hemoglobins
E3S73_RS05575	COG1164	Oligoendopeptidase f
E3S73_RS05610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S73_RS05625	COG0444	Belongs to the ABC transporter superfamily
E3S73_RS05635	COG2826	transposase and inactivated derivatives, IS30 family
E3S73_RS05645	COG4166	transmembrane transport
E3S73_RS05650	COG4608	Belongs to the ABC transporter superfamily
E3S73_RS05655	COG0444	Belongs to the ABC transporter superfamily
E3S73_RS05660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S73_RS05665	COG0601	transmembrane transport
E3S73_RS05695	COG1881	PFAM PEBP family protein
E3S73_RS05735	COG0561	phosphatase activity
E3S73_RS05780	COG0398	Pfam SNARE associated Golgi protein
E3S73_RS05800	COG0584	glycerophosphoryl diester phosphodiesterase
E3S73_RS05815	COG1902	pentaerythritol trinitrate reductase activity
E3S73_RS05820	COG1098	S1 RNA binding domain
E3S73_RS05875	COG2050	protein possibly involved in aromatic compounds catabolism
E3S73_RS05880	COG2056	Na+-H+ antiporter family
E3S73_RS05885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3S73_RS05895	COG0316	Belongs to the HesB IscA family
E3S73_RS05905	COG1252	NADH dehydrogenase
E3S73_RS05910	COG4837	Protein of unknown function (DUF1462)
E3S73_RS05915	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3S73_RS05920	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E3S73_RS05930	COG1696	Membrane protein involved in D-alanine export
E3S73_RS05960	COG2445	Protein of unknown function DUF86
E3S73_RS05970	COG4470	Protein conserved in bacteria
E3S73_RS05985	COG0730	response to heat
E3S73_RS05990	COG1801	Protein of unknown function DUF72
E3S73_RS06000	COG1253	flavin adenine dinucleotide binding
E3S73_RS06020	COG0822	iron-sulfur transferase activity
E3S73_RS06030	COG0719	Fe-S assembly protein
E3S73_RS06035	COG0396	ATPase activity
E3S73_RS06050	COG1464	Belongs to the NlpA lipoprotein family
E3S73_RS06055	COG2011	ABC-type metal ion transport system permease component
E3S73_RS06075	COG3878	Protein conserved in bacteria
E3S73_RS06090	COG1393	Belongs to the ArsC family
E3S73_RS06095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S73_RS06120	COG1279	arginine transmembrane transporter activity
E3S73_RS06165	COG1278	Cold shock
E3S73_RS06230	COG0557	exoribonuclease II activity
E3S73_RS06235	COG1647	Serine aminopeptidase, S33
E3S73_RS06240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S73_RS06290	COG0281	malic enzyme
E3S73_RS06305	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3S73_RS06360	COG1388	LysM domain
E3S73_RS06360	COG3942	CHAP domain
E3S73_RS06385	COG1040	competence protein
E3S73_RS06390	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E3S73_RS06400	COG1739	Uncharacterized protein family UPF0029
E3S73_RS06405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3S73_RS06460	COG4607	ABC-type enterochelin transport system periplasmic component
E3S73_RS06465	COG4604	ABC transporter, ATP-binding protein
E3S73_RS06470	COG4605	iron ion homeostasis
E3S73_RS06475	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S73_RS06480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S73_RS06485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S73_RS06505	COG3104	oligopeptide transport
E3S73_RS06530	COG1174	glycine betaine transport
E3S73_RS06535	COG1125	glycine betaine transport
E3S73_RS06535	COG0517	IMP dehydrogenase activity
E3S73_RS06540	COG0514	ATP-dependent DNA helicase (RecQ)
E3S73_RS06545	COG0488	(ABC) transporter
E3S73_RS06575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S73_RS06580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3S73_RS06580	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S73_RS06590	COG0720	synthase
E3S73_RS06625	COG0463	Glycosyl transferase, family 2
E3S73_RS06630	COG0656	L-ascorbic acid biosynthetic process
E3S73_RS06635	COG1253	flavin adenine dinucleotide binding
E3S73_RS06640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3S73_RS06645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S73_RS06645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S73_RS06645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S73_RS06650	COG1105	Belongs to the carbohydrate kinase PfkB family
E3S73_RS06655	COG1349	DNA-binding transcription factor activity
E3S73_RS06660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3S73_RS06695	COG0471	metal ion transport
E3S73_RS06705	COG4989	oxidoreductase activity
E3S73_RS06710	COG0523	cobalamin synthesis protein
E3S73_RS06715	COG1846	Transcriptional regulator
E3S73_RS06720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3S73_RS06725	COG4988	ABC transporter
E3S73_RS06745	COG1611	Belongs to the LOG family
E3S73_RS06780	COG2839	Protein conserved in bacteria
E3S73_RS06785	COG2814	Major facilitator Superfamily
E3S73_RS06790	COG0583	DNA-binding transcription factor activity
E3S73_RS06820	COG4977	sequence-specific DNA binding
E3S73_RS06820	COG1917	Cupin 2, conserved barrel domain protein
E3S73_RS06830	COG1388	LysM domain
E3S73_RS06830	COG3942	CHAP domain
E3S73_RS06835	COG0306	phosphate transporter
E3S73_RS06840	COG1392	Phosphate transport regulator
E3S73_RS06845	COG0577	efflux transmembrane transporter activity
E3S73_RS06850	COG1136	(ABC) transporter
E3S73_RS06885	COG3949	Membrane
E3S73_RS06905	COG2376	Dihydroxyacetone kinase
E3S73_RS06910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S73_RS06915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S73_RS06920	COG1120	ATPase activity
E3S73_RS06925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E3S73_RS06935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S73_RS06940	COG1132	(ABC) transporter
E3S73_RS06945	COG1686	Belongs to the peptidase S11 family
E3S73_RS06950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3S73_RS06960	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S73_RS06965	COG1682	transport, permease protein
E3S73_RS06985	COG1321	iron dependent repressor
E3S73_RS06990	COG1121	(ABC) transporter
E3S73_RS06995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S73_RS07000	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S73_RS07010	COG2814	Major facilitator Superfamily
E3S73_RS07105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S73_RS07110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S73_RS07145	COG1078	dGTPase activity
E3S73_RS07155	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S73_RS07160	COG0667	Aldo Keto reductase
E3S73_RS07200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S73_RS07220	COG0083	homoserine kinase activity
E3S73_RS07225	COG0095	Lipoate-protein ligase
E3S73_RS07330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3S73_RS07355	COG4932	domain protein
E3S73_RS07370	COG0561	phosphatase activity
E3S73_RS07380	COG1428	Deoxynucleoside kinase
E3S73_RS07385	COG1428	Deoxynucleoside kinase
E3S73_RS07390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3S73_RS07420	COG1473	amidohydrolase
E3S73_RS07460	COG2813	Specifically methylates the guanine in position
E3S73_RS07490	COG0250	Participates in transcription elongation, termination and antitermination
E3S73_RS07495	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S73_RS07520	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3S73_RS07540	COG4956	integral membrane protein (PIN domain superfamily)
E3S73_RS07545	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3S73_RS07560	COG3880	PFAM UvrB UvrC protein
E3S73_RS07570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S73_RS07585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S73_RS07680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3S73_RS07705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3S73_RS07720	COG1098	S1 RNA binding domain
E3S73_RS07730	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3S73_RS07735	COG3956	TIGRFAM MazG family protein
E3S73_RS07740	COG2244	polysaccharide biosynthetic process
E3S73_RS07780	COG0251	oxidation-reduction process
E3S73_RS07785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3S73_RS07795	COG4466	Protein conserved in bacteria
E3S73_RS07805	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S73_RS07810	COG0084	hydrolase, TatD family'
E3S73_RS07820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3S73_RS07830	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3S73_RS07840	COG1774	PSP1 C-terminal conserved region
E3S73_RS07845	COG0470	DNA polymerase III
E3S73_RS07850	COG3870	Protein conserved in bacteria
E3S73_RS07860	COG1982	Orn Lys Arg decarboxylase major
E3S73_RS07890	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E3S73_RS07895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3S73_RS07915	COG2188	Transcriptional regulator
E3S73_RS07920	COG0366	Alpha amylase catalytic
E3S73_RS07925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S73_RS07925	COG1263	PTS System
E3S73_RS07935	COG0493	'glutamate synthase
E3S73_RS07940	COG0070	glutamate synthase
E3S73_RS07940	COG0069	glutamate synthase activity
E3S73_RS07940	COG0067	glutamate synthase
E3S73_RS07945	COG0583	DNA-binding transcription factor activity
E3S73_RS07980	COG1464	Belongs to the NlpA lipoprotein family
E3S73_RS07985	COG2011	ABC-type metal ion transport system permease component
E3S73_RS07995	COG0626	cystathionine gamma-synthase activity
E3S73_RS08000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3S73_RS08005	COG0733	neurotransmitter:sodium symporter activity
E3S73_RS08015	COG1647	Serine aminopeptidase, S33
E3S73_RS08030	COG5609	conserved protein (DUF2294)
E3S73_RS08040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3S73_RS08065	COG0523	cobalamin synthesis protein
E3S73_RS08190	COG3759	membrane
E3S73_RS08225	COG2233	PERMEase
E3S73_RS08255	COG1823	symporter activity
E3S73_RS08360	COG5484	DNA packaging
E3S73_RS08360	COG3728	DNA packaging
E3S73_RS08475	COG0012	GTP binding
E3S73_RS08480	COG4481	Protein conserved in bacteria
E3S73_RS08485	COG0668	transmembrane transport
E3S73_RS08490	COG1475	DNA binding
E3S73_RS08495	COG0626	cystathionine gamma-synthase activity
E3S73_RS08500	COG0626	cystathionine gamma-synthase activity
E3S73_RS08505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3S73_RS08505	COG0646	methionine synthase
E3S73_RS08535	COG1131	(ABC) transporter
E3S73_RS08545	COG1476	TRANSCRIPTIONal
E3S73_RS08555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3S73_RS08560	COG0805	protein transport
E3S73_RS08565	COG0672	)-iron permease
E3S73_RS08570	COG2837	iron assimilation
E3S73_RS08575	COG2822	iron ion transport
E3S73_RS08595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S73_RS08600	COG0346	lactoylglutathione lyase activity
E3S73_RS08605	COG2271	Major facilitator Superfamily
E3S73_RS08630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S73_RS08640	COG3037	sugar-specific permease SgaT UlaA
E3S73_RS08670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S73_RS08720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3S73_RS08725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S73_RS08755	COG0577	efflux transmembrane transporter activity
E3S73_RS08760	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E3S73_RS08765	COG1114	Component of the transport system for branched-chain amino acids
E3S73_RS08900	COG1388	LysM domain
E3S73_RS08900	COG3942	CHAP domain
E3S73_RS08975	COG2226	methyltransferase
E3S73_RS08980	COG2723	6-phospho-beta-galactosidase activity
E3S73_RS08985	COG2190	(PTS) system
E3S73_RS08985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S73_RS08985	COG1263	PTS System
E3S73_RS08990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S73_RS09030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S73_RS09035	COG1063	alcohol dehydrogenase
E3S73_RS09045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S73_RS09050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S73_RS09055	COG1063	alcohol dehydrogenase
E3S73_RS09065	COG1063	alcohol dehydrogenase
E3S73_RS09075	COG1063	alcohol dehydrogenase
E3S73_RS09080	COG3775	system Galactitol-specific IIC component
E3S73_RS09085	COG3414	Phosphotransferase system galactitol-specific IIB component
E3S73_RS09105	COG1957	nucleoside hydrolase
E3S73_RS09110	COG1263	PTS System
E3S73_RS09110	COG2190	(PTS) system
E3S73_RS09110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S73_RS09135	COG3189	MarR family transcriptional regulator
E3S73_RS09140	COG0747	negative chemotaxis
E3S73_RS09160	COG0318	PFAM AMP-dependent synthetase and ligase
E3S73_RS09165	COG1960	acyl-CoA dehydrogenase activity
E3S73_RS09175	COG0183	Belongs to the thiolase family
E3S73_RS09230	COG1755	Isoprenylcysteine carboxyl methyltransferase
E3S73_RS09240	COG0673	inositol 2-dehydrogenase activity
E3S73_RS09245	COG0673	inositol 2-dehydrogenase activity
E3S73_RS09250	COG3833	ABC-type maltose transport systems, permease component
E3S73_RS09255	COG1175	transmembrane transport
E3S73_RS09265	COG3842	ATPase activity
E3S73_RS09280	COG0405	Gamma-glutamyltransferase
E3S73_RS09290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S73_RS09320	COG1737	Transcriptional regulator
E3S73_RS09350	COG3961	Belongs to the TPP enzyme family
E3S73_RS09355	COG1335	isochorismatase
E3S73_RS09360	COG1114	Component of the transport system for branched-chain amino acids
E3S73_RS09410	COG5609	conserved protein (DUF2294)
E3S73_RS09415	COG1960	acyl-CoA dehydrogenase activity
E3S73_RS09420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3S73_RS09455	COG2832	Protein of unknown function (DUF454)
E3S73_RS09465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S73_RS09470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3S73_RS09480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S73_RS09510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S73_RS09520	COG1086	Polysaccharide biosynthesis protein
E3S73_RS09545	COG1012	belongs to the aldehyde dehydrogenase family
E3S73_RS09545	COG1454	alcohol dehydrogenase
E3S73_RS09560	COG0737	Belongs to the 5'-nucleotidase family
E3S73_RS09580	COG3639	organic phosphonate transmembrane transporter activity
E3S73_RS09600	COG2814	Major facilitator Superfamily
E3S73_RS09605	COG0813	purine-nucleoside phosphorylase activity
E3S73_RS09635	COG0438	transferase activity, transferring glycosyl groups
E3S73_RS09640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S73_RS09645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3S73_RS09665	COG1475	DNA binding
E3S73_RS09670	COG0019	diaminopimelate decarboxylase activity
E3S73_RS09680	COG4264	IucA IucC family
E3S73_RS09685	COG4264	IucA IucC family
E3S73_RS09690	COG2814	Major facilitator Superfamily
E3S73_RS09695	COG4264	IucA IucC family
E3S73_RS09700	COG2423	ornithine cyclodeaminase activity
E3S73_RS09710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S73_RS09715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S73_RS09720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S73_RS09735	COG1620	l-lactate permease
E3S73_RS09745	COG4716	Myosin-crossreactive antigen
E3S73_RS09750	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3S73_RS09760	COG1473	amidohydrolase
E3S73_RS09775	COG2826	transposase and inactivated derivatives, IS30 family
E3S73_RS09785	COG0823	Involved in the tonB-independent uptake of proteins
E3S73_RS09820	COG0456	acetyltransferase
E3S73_RS09840	COG2814	Major facilitator Superfamily
E3S73_RS09860	COG4268	DNA restriction-modification system
E3S73_RS09865	COG1401	restriction endodeoxyribonuclease activity
E3S73_RS09875	COG2826	transposase and inactivated derivatives, IS30 family
E3S73_RS09920	COG1136	(ABC) transporter
E3S73_RS09920	COG0577	efflux transmembrane transporter activity
E3S73_RS09965	COG3316	Transposase and inactivated derivatives
E3S73_RS10010	COG0583	DNA-binding transcription factor activity
E3S73_RS10040	COG2826	transposase and inactivated derivatives, IS30 family
E3S73_RS10055	COG0737	Belongs to the 5'-nucleotidase family
E3S73_RS10060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3S73_RS10070	COG4863	YycH protein
E3S73_RS10100	COG0305	Participates in initiation and elongation during chromosome replication
E3S73_RS10110	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E3S73_RS10120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3S73_RS10145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3S73_RS10165	COG2501	S4 domain
E3S73_RS10205	COG1475	DNA binding
E3S73_RS10225	COG1278	Cold shock
E3S73_RS10255	COG0577	efflux transmembrane transporter activity
E3S73_RS10260	COG1136	(ABC) transporter
E3S73_RS10275	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3S73_RS10285	COG2962	Rard protein
E3S73_RS10290	COG0471	metal ion transport
E3S73_RS10370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3S73_RS10420	COG1215	transferase activity, transferring glycosyl groups
E3S73_RS10425	COG1309	transcriptional regulator
E3S73_RS10455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S73_RS10480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S73_RS10490	COG0201	protein transport
E3S73_RS10515	COG0438	transferase activity, transferring glycosyl groups
E3S73_RS10530	COG3433	isochorismatase activity
E3S73_RS10530	COG1535	isochorismatase
E3S73_RS10535	COG3942	CHAP domain
E3S73_RS10535	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3S73_RS10545	COG1482	cell wall glycoprotein biosynthetic process
E3S73_RS10550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S73_RS10550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S73_RS10550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S73_RS10555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S73_RS10555	COG3711	transcriptional antiterminator
E3S73_RS10575	COG1438	arginine binding
E3S73_RS10620	COG1846	Transcriptional regulator
E3S73_RS10630	COG1785	Belongs to the alkaline phosphatase family
E3S73_RS10645	COG0745	RESPONSE REGULATOR receiver
E3S73_RS10650	COG2205	protein histidine kinase activity
E3S73_RS10655	COG1136	(ABC) transporter
E3S73_RS10675	COG0386	Belongs to the glutathione peroxidase family
E3S73_RS10685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3S73_RS10700	COG2851	Citrate transporter
E3S73_RS10725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S73_RS10730	COG1510	regulation of RNA biosynthetic process
E3S73_RS10760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S73_RS10790	COG0531	amino acid
E3S73_RS10800	COG3527	Alpha-acetolactate decarboxylase
E3S73_RS10855	COG0167	dihydroorotate dehydrogenase activity
E3S73_RS10995	COG0436	Aminotransferase
E3S73_RS11040	COG2409	Drug exporters of the RND superfamily
E3S73_RS11065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3S73_RS11070	COG3425	synthase
E3S73_RS11080	COG3942	CHAP domain
E3S73_RS11090	COG0583	DNA-binding transcription factor activity
E3S73_RS11105	COG0028	Belongs to the TPP enzyme family
E3S73_RS11125	COG0657	acetylesterase activity
E3S73_RS11130	COG0697	spore germination
E3S73_RS11145	COG1760	l-serine dehydratase
E3S73_RS11150	COG1760	l-serine dehydratase
E3S73_RS11170	COG3764	Sortase (surface protein transpeptidase)
E3S73_RS11175	COG0561	phosphatase activity
E3S73_RS11195	COG2514	catechol 2,3-dioxygenase activity
E3S73_RS11205	COG1846	Transcriptional regulator
E3S73_RS11210	COG0346	lactoylglutathione lyase activity
E3S73_RS11215	COG0400	carboxylic ester hydrolase activity
E3S73_RS11235	COG1131	(ABC) transporter
E3S73_RS11240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S73_RS11250	COG1279	arginine transmembrane transporter activity
E3S73_RS11255	COG0586	Pfam SNARE associated Golgi protein
E3S73_RS11260	COG2271	Major facilitator Superfamily
E3S73_RS11270	COG4876	unkown
E3S73_RS11275	COG2357	RelA SpoT domain protein
E3S73_RS11280	COG0789	Transcriptional regulator
E3S73_RS11285	COG1802	Transcriptional regulator
E3S73_RS11290	COG1070	Carbohydrate kinase
E3S73_RS11340	COG0494	nUDIX hydrolase
E3S73_RS11395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3S73_RS11400	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3S73_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
E3S73_RS11410	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3S73_RS11430	COG0747	negative chemotaxis
E3S73_RS11435	COG0601	transmembrane transport
E3S73_RS11440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S73_RS11450	COG1124	(ABC) transporter
E3S73_RS11465	COG0069	glutamate synthase activity
E3S73_RS11470	COG4808	Protein conserved in bacteria
E3S73_RS11485	COG1363	Peptidase, m42
E3S73_RS11490	COG4619	ABC transporter
E3S73_RS11495	COG0390	transport system, permease component
E3S73_RS11500	COG2814	Major facilitator Superfamily
E3S73_RS11545	COG0531	amino acid
E3S73_RS11550	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E3S73_RS11570	COG1174	glycine betaine transport
E3S73_RS11580	COG1174	glycine betaine transport
E3S73_RS11590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S73_RS11605	COG0531	amino acid
E3S73_RS11615	COG1113	amino acid transport
E3S73_RS11635	COG2814	Major facilitator Superfamily
E3S73_RS11645	COG1929	Belongs to the glycerate kinase type-1 family
E3S73_RS11665	COG1132	(ABC) transporter
E3S73_RS11675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3S73_RS11680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3S73_RS11690	COG0156	8-amino-7-oxononanoate synthase activity
E3S73_RS11730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E3S73_RS11745	COG2814	Major facilitator Superfamily
E3S73_RS11750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3S73_RS11755	COG0765	amino acid transport
E3S73_RS11760	COG1126	abc transporter atp-binding protein
E3S73_RS11780	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S73_RS11780	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3S73_RS11795	COG2116	formate transmembrane transporter activity
E3S73_RS11800	COG0454	-acetyltransferase
E3S73_RS11810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3S73_RS11815	COG2146	nitrite reductase [NAD(P)H] activity
E3S73_RS11825	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3S73_RS11830	COG1140	nitrate reductase beta subunit
E3S73_RS11840	COG2181	nitrate reductase activity
E3S73_RS11860	COG0789	Transcriptional regulator
E3S73_RS11900	COG3871	stress protein (general stress protein 26)
E3S73_RS11915	COG1263	PTS System
E3S73_RS11915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S73_RS11930	COG1511	domain protein
E3S73_RS11955	COG0604	alcohol dehydrogenase
E3S73_RS11975	COG1620	l-lactate permease
E3S73_RS11990	COG1131	(ABC) transporter
E3S73_RS12050	COG2814	Major facilitator Superfamily
E3S73_RS12065	COG1566	PFAM secretion protein HlyD family protein
E3S73_RS12070	COG2814	Major facilitator Superfamily
E3S73_RS12080	COG0657	acetylesterase activity
E3S73_RS12095	COG0598	Magnesium transport protein CorA
E3S73_RS12105	COG0786	glutamate:sodium symporter activity
E3S73_RS12120	COG4152	abc transporter atp-binding protein
E3S73_RS12125	COG1668	transmembrane transport
E3S73_RS12145	COG2258	MOSC domain
E3S73_RS12170	COG0583	DNA-binding transcription factor activity
E3S73_RS12185	COG1473	amidohydrolase
E3S73_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
E3S73_RS12210	COG1737	Transcriptional regulator
E3S73_RS12215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S73_RS12215	COG1263	PTS System
E3S73_RS12225	COG0385	Bile acid
E3S73_RS12230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3S73_RS12250	COG1113	amino acid transport
E3S73_RS12330	COG1757	Na H antiporter
E3S73_RS12400	COG4413	Urea transporter
E3S73_RS12405	COG1960	acyl-CoA dehydrogenase activity
E3S73_RS12420	COG1268	BioY protein
E3S73_RS12435	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3S73_RS12440	COG4149	molybdate abc transporter
E3S73_RS12445	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3S73_RS12450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3S73_RS12470	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3S73_RS12530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3S73_RS12575	COG2252	PERMEase
E3S73_RS12690	COG0201	protein transport
E3S73_RS12780	COG0028	Belongs to the TPP enzyme family
E3S73_RS12785	COG3527	Alpha-acetolactate decarboxylase
E3S73_RS12805	COG5492	domain, Protein
E3S73_RS12815	COG0789	Transcriptional regulator
E3S73_RS12820	COG0656	L-ascorbic acid biosynthetic process
E3S73_RS12895	COG2130	NADP-dependent
E3S73_RS12905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S73_RS12930	COG2814	Major facilitator Superfamily
E3S73_RS12935	COG4264	IucA IucC family
E3S73_RS12940	COG3457	Alanine racemase
E3S73_RS12950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S73_RS12955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S73_RS12960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S73_RS12975	COG1988	membrane-bound metal-dependent
E3S73_RS12985	COG1272	protein, Hemolysin III
E3S73_RS13000	COG2814	Major facilitator Superfamily
E3S73_RS13005	COG0489	protein tyrosine kinase activity
E3S73_RS13065	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E3S73_RS13095	COG3711	transcriptional antiterminator
E3S73_RS13110	COG1119	ATPase activity
E3S73_RS13115	COG0561	phosphatase activity
E3S73_RS13140	COG0640	Transcriptional regulator
E3S73_RS13145	COG0702	epimerase
E3S73_RS13150	COG1482	cell wall glycoprotein biosynthetic process
E3S73_RS13170	COG0783	Belongs to the Dps family
E3S73_RS13175	COG0813	purine-nucleoside phosphorylase activity
E3S73_RS13220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S73_RS13260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3S73_RS13280	COG2890	protein-(glutamine-N5) methyltransferase activity
E3S73_RS13285	COG0009	L-threonylcarbamoyladenylate synthase
E3S73_RS13310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S73_RS13385	COG0629	single-stranded DNA binding
E3S73_RS13430	COG1418	mRNA catabolic process
E3S73_RS13440	COG1937	Protein conserved in bacteria
E3S73_RS13460	COG0772	Belongs to the SEDS family
E3S73_RS13470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3S73_RS13480	COG0745	RESPONSE REGULATOR receiver
E3S73_RS13485	COG2205	protein histidine kinase activity
E3S73_RS13515	COG3428	Bacterial PH domain
E3S73_RS13545	COG2208	phosphoserine phosphatase activity
E3S73_RS13550	COG1366	Belongs to the anti-sigma-factor antagonist family
E3S73_RS13560	COG1191	sigma factor activity
E3S73_RS13565	COG2183	response to ionizing radiation
E3S73_RS13640	COG0028	Belongs to the TPP enzyme family
E3S73_RS13655	COG0802	atpase or kinase
E3S73_RS13660	COG1214	PFAM Peptidase M22, glycoprotease
E3S73_RS13665	COG0456	acetyltransferase
E3S73_RS13675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E3S73_RS13685	COG0488	(ABC) transporter
E3S73_RS13695	COG2391	methyltransferase activity
E3S73_RS13700	COG0425	Belongs to the sulfur carrier protein TusA family
E3S73_RS13705	COG0004	ammonium transporteR
E3S73_RS13710	COG1609	Transcriptional regulator
E3S73_RS13715	COG1621	beta-fructofuranosidase activity
E3S73_RS13720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3S73_RS13790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA