locus-tag	class	description
E3S77_RS00015	COG4695	Portal protein
E3S77_RS00070	COG0739	heme binding
E3S77_RS00115	COG1388	LysM domain
E3S77_RS00115	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S77_RS00125	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S77_RS00125	COG1388	LysM domain
E3S77_RS00175	COG1725	Transcriptional regulator
E3S77_RS00190	COG1131	(ABC) transporter
E3S77_RS00240	COG4974	Belongs to the 'phage' integrase family
E3S77_RS00280	COG1012	belongs to the aldehyde dehydrogenase family
E3S77_RS00295	COG1335	isochorismatase
E3S77_RS00315	COG0077	Prephenate dehydratase
E3S77_RS00325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3S77_RS00360	COG4496	protein, YerC YecD
E3S77_RS00380	COG4851	CamS sex pheromone cAM373 precursor
E3S77_RS00385	COG2070	2-Nitropropane dioxygenase
E3S77_RS00510	COG1295	ribonuclease BN
E3S77_RS00530	COG2309	aminopeptidase activity
E3S77_RS00535	COG1607	acyl-coa hydrolase
E3S77_RS00540	COG0535	radical SAM domain protein
E3S77_RS00580	COG1388	LysM domain
E3S77_RS00580	COG1134	teichoic acid transport
E3S77_RS00590	COG1988	membrane-bound metal-dependent
E3S77_RS00610	COG4129	membrane
E3S77_RS00620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3S77_RS00800	COG0765	amino acid transport
E3S77_RS00805	COG1126	abc transporter atp-binding protein
E3S77_RS00810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3S77_RS00840	COG0564	pseudouridine synthase activity
E3S77_RS00845	COG4585	Histidine kinase
E3S77_RS00845	COG2203	Gaf domain
E3S77_RS00850	COG2197	response regulator
E3S77_RS00870	COG0420	3'-5' exonuclease activity
E3S77_RS00900	COG0537	adenosine 5'-monophosphoramidase activity
E3S77_RS00905	COG1131	(ABC) transporter
E3S77_RS01110	COG0732	type I restriction modification DNA specificity domain
E3S77_RS01180	COG2816	NAD+ diphosphatase activity
E3S77_RS01185	COG1506	peptidase
E3S77_RS01205	COG0656	L-ascorbic acid biosynthetic process
E3S77_RS01225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3S77_RS01255	COG4193	domain, Protein
E3S77_RS01255	COG3266	domain, Protein
E3S77_RS01255	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S77_RS01280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S77_RS01280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S77_RS01310	COG2267	carboxylic ester hydrolase activity
E3S77_RS01315	COG1846	Transcriptional regulator
E3S77_RS01320	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3S77_RS01325	COG1242	4 iron, 4 sulfur cluster binding
E3S77_RS01330	COG2814	Major facilitator Superfamily
E3S77_RS01350	COG2081	HI0933 family
E3S77_RS01355	COG2244	polysaccharide biosynthetic process
E3S77_RS01360	COG1187	pseudouridine synthase activity
E3S77_RS01380	COG0510	thiamine kinase activity
E3S77_RS01400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S77_RS01410	COG1363	Peptidase, m42
E3S77_RS01415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S77_RS01425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3S77_RS01430	COG1674	ftsk spoiiie
E3S77_RS01455	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E3S77_RS01455	COG1605	Chorismate mutase
E3S77_RS01475	COG0454	-acetyltransferase
E3S77_RS01480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S77_RS01515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3S77_RS01520	COG0204	Acyl-transferase
E3S77_RS01525	COG1263	PTS System
E3S77_RS01525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S77_RS01540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S77_RS01545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E3S77_RS01550	COG1764	response to oxidative stress
E3S77_RS01555	COG0584	glycerophosphoryl diester phosphodiesterase
E3S77_RS01570	COG1956	GAF domain-containing protein
E3S77_RS01580	COG1104	cysteine desulfurase activity
E3S77_RS01590	COG0730	response to heat
E3S77_RS01600	COG0827	DNA restriction-modification system
E3S77_RS01640	COG4109	DRTGG domain
E3S77_RS01645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3S77_RS01655	COG0281	malic enzyme
E3S77_RS01680	COG1113	amino acid transport
E3S77_RS01685	COG0372	Belongs to the citrate synthase family
E3S77_RS01695	COG0745	RESPONSE REGULATOR receiver
E3S77_RS01700	COG5002	protein histidine kinase activity
E3S77_RS01710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S77_RS01710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S77_RS01715	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3S77_RS01740	COG1484	DNA-dependent DNA replication
E3S77_RS01755	COG0833	amino acid
E3S77_RS01775	COG4112	unkown
E3S77_RS01810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3S77_RS01825	COG0113	porphobilinogen synthase activity
E3S77_RS01850	COG2818	Glycosylase
E3S77_RS01860	COG0285	dihydrofolate synthase activity
E3S77_RS01865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E3S77_RS01910	COG2868	ribosomal protein
E3S77_RS01950	COG1862	Preprotein translocase
E3S77_RS01955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S77_RS01955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S77_RS01960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3S77_RS01960	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E3S77_RS02005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3S77_RS02010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3S77_RS02015	COG1959	2 iron, 2 sulfur cluster binding
E3S77_RS02030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S77_RS02035	COG1104	cysteine desulfurase activity
E3S77_RS02050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3S77_RS02100	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3S77_RS02105	COG1984	allophanate hydrolase subunit 2
E3S77_RS02110	COG0511	ligase activity, forming carbon-carbon bonds
E3S77_RS02115	COG0439	Biotin carboxylase
E3S77_RS02125	COG1914	H( )-stimulated, divalent metal cation uptake system
E3S77_RS02150	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E3S77_RS02155	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E3S77_RS02165	COG1534	Rna-binding protein
E3S77_RS02175	COG1713	HD superfamily hydrolase involved in NAD metabolism
E3S77_RS02180	COG0799	negative regulation of ribosome biogenesis
E3S77_RS02185	COG2226	methyltransferase
E3S77_RS02190	COG2183	response to ionizing radiation
E3S77_RS02195	COG2131	deaminase
E3S77_RS02200	COG0658	competence protein
E3S77_RS02200	COG2333	competence protein COMEC
E3S77_RS02205	COG1466	dna polymerase III delta subunit
E3S77_RS02220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3S77_RS02250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3S77_RS02255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3S77_RS02265	COG1030	water channel activity
E3S77_RS02280	COG1702	phosphate starvation-inducible protein PhoH
E3S77_RS02295	COG0295	cytidine deaminase activity
E3S77_RS02315	COG0517	IMP dehydrogenase activity
E3S77_RS02330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3S77_RS02335	COG2384	SAM-dependent methyltransferase
E3S77_RS02345	COG0513	Belongs to the DEAD box helicase family
E3S77_RS02355	COG1121	(ABC) transporter
E3S77_RS02360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S77_RS02365	COG0735	belongs to the Fur family
E3S77_RS02385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3S77_RS02395	COG4483	Protein conserved in bacteria
E3S77_RS02400	COG1940	carbohydrate kinase activity
E3S77_RS02405	COG0011	TIGRFAM Protein of
E3S77_RS02410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S77_RS02415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3S77_RS02420	COG1459	type II secretion system
E3S77_RS02425	COG4537	Required for transformation and DNA binding
E3S77_RS02470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3S77_RS02475	COG0095	Lipoate-protein ligase
E3S77_RS02490	COG0006	proline dipeptidase activity
E3S77_RS02500	COG0511	ligase activity, forming carbon-carbon bonds
E3S77_RS02505	COG0439	Biotin carboxylase
E3S77_RS02510	COG1302	Protein conserved in bacteria
E3S77_RS02540	COG0497	DNA recombination
E3S77_RS02545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S77_RS02550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E3S77_RS02555	COG0022	dehydrogenase e1 component
E3S77_RS02560	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3S77_RS02575	COG4129	membrane
E3S77_RS02585	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3S77_RS02605	COG1609	Transcriptional regulator
E3S77_RS02610	COG0366	Alpha amylase catalytic
E3S77_RS02620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3S77_RS02635	COG4221	oxidoreductase activity
E3S77_RS02645	COG0667	Aldo Keto reductase
E3S77_RS02650	COG0494	nUDIX hydrolase
E3S77_RS02655	COG0735	belongs to the Fur family
E3S77_RS02680	COG1187	pseudouridine synthase activity
E3S77_RS02685	COG0745	RESPONSE REGULATOR receiver
E3S77_RS02690	COG5002	protein histidine kinase activity
E3S77_RS02735	COG1141	Ferredoxin
E3S77_RS02745	COG0514	ATP-dependent DNA helicase (RecQ)
E3S77_RS02760	COG0492	ferredoxin-NADP+ reductase activity
E3S77_RS02815	COG0142	geranyltranstransferase activity
E3S77_RS02855	COG4347	Protein of unknown function (DUF1405)
E3S77_RS02860	COG2738	Putative neutral zinc metallopeptidase
E3S77_RS02865	COG1694	Mazg nucleotide pyrophosphohydrolase
E3S77_RS02870	COG0438	transferase activity, transferring glycosyl groups
E3S77_RS02895	COG3935	DnaD domain protein
E3S77_RS02900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3S77_RS02910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3S77_RS02910	COG4499	WXG100 protein secretion system (Wss), protein YukC
E3S77_RS02945	COG0116	Belongs to the methyltransferase superfamily
E3S77_RS02960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3S77_RS02965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S77_RS02980	COG0531	amino acid
E3S77_RS03000	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3S77_RS03040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S77_RS03070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
E3S77_RS03075	COG0671	phosphoesterase, PA-phosphatase related
E3S77_RS03125	COG4548	von Willebrand factor, type A
E3S77_RS03165	COG2808	Putative FMN-binding domain
E3S77_RS03200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3S77_RS03205	COG0527	aspartate kinase activity
E3S77_RS03210	COG0488	(ABC) transporter
E3S77_RS03225	COG0573	inorganic phosphate transmembrane transporter activity
E3S77_RS03230	COG0581	inorganic phosphate transmembrane transporter activity
E3S77_RS03240	COG0704	Plays a role in the regulation of phosphate uptake
E3S77_RS03285	COG0561	phosphatase activity
E3S77_RS03290	COG2348	transferase activity, transferring amino-acyl groups
E3S77_RS03325	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S77_RS03330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S77_RS03335	COG1363	Peptidase, m42
E3S77_RS03345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3S77_RS03355	COG1316	TRANSCRIPTIONal
E3S77_RS03360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S77_RS03370	COG0628	permease
E3S77_RS03385	COG1115	amino acid carrier protein
E3S77_RS03390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E3S77_RS03395	COG0187	DNA topoisomerase II activity
E3S77_RS03410	COG0824	Thioesterase
E3S77_RS03420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S77_RS03440	COG4846	Membrane protein involved in cytochrome C biogenesis
E3S77_RS03475	COG2340	Cysteine-rich secretory protein family
E3S77_RS03505	COG0833	amino acid
E3S77_RS03530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3S77_RS03535	COG0460	homoserine dehydrogenase
E3S77_RS03540	COG0527	aspartate kinase activity
E3S77_RS03555	COG1525	nuclease
E3S77_RS03565	COG2197	response regulator
E3S77_RS03580	COG1131	(ABC) transporter
E3S77_RS03735	COG1595	DNA-templated transcription, initiation
E3S77_RS03855	COG0582	viral genome integration into host DNA
E3S77_RS03865	COG0789	Transcriptional regulator
E3S77_RS03870	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E3S77_RS03890	COG1923	regulation of RNA biosynthetic process
E3S77_RS03915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3S77_RS03920	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3S77_RS03955	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3S77_RS03960	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3S77_RS03960	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3S77_RS03965	COG1692	metallophosphoesterase
E3S77_RS03985	COG1058	Belongs to the CinA family
E3S77_RS03985	COG1546	Belongs to the CinA family
E3S77_RS04005	COG0300	oxidoreductase activity
E3S77_RS04010	COG0612	Peptidase, M16
E3S77_RS04015	COG0612	Peptidase, M16
E3S77_RS04020	COG2188	Transcriptional regulator
E3S77_RS04045	COG0196	riboflavin kinase activity
E3S77_RS04070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E3S77_RS04075	COG0195	Participates in both transcription termination and antitermination
E3S77_RS04170	COG0758	DNA mediated transformation
E3S77_RS04175	COG2348	transferase activity, transferring amino-acyl groups
E3S77_RS04180	COG1388	LysM domain
E3S77_RS04180	COG1388	LysM domain
E3S77_RS04235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3S77_RS04245	COG0552	protein localization to endoplasmic reticulum
E3S77_RS04250	COG1196	nuclear chromosome segregation
E3S77_RS04295	COG1302	Protein conserved in bacteria
E3S77_RS04310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3S77_RS04325	COG0631	protein serine/threonine phosphatase activity
E3S77_RS04335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3S77_RS04335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3S77_RS04350	COG2314	TM2 domain
E3S77_RS04360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3S77_RS04365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3S77_RS04430	COG2233	PERMEase
E3S77_RS04440	COG0564	pseudouridine synthase activity
E3S77_RS04460	COG2514	catechol 2,3-dioxygenase activity
E3S77_RS04470	COG3599	regulation of cell shape
E3S77_RS04480	COG0762	integral membrane protein
E3S77_RS04490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3S77_RS04500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3S77_RS04505	COG0849	cell division
E3S77_RS04510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E3S77_RS04530	COG4839	cell division protein FtsL
E3S77_RS04555	COG1011	Hydrolase
E3S77_RS04590	COG1288	antiporter activity
E3S77_RS04690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3S77_RS04695	COG1053	succinate dehydrogenase
E3S77_RS04700	COG2009	succinate dehydrogenase
E3S77_RS04725	COG1796	DNA polymerase
E3S77_RS04725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3S77_RS04755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3S77_RS04770	COG4509	Sortase family
E3S77_RS04825	COG0742	ribosomal rna small subunit methyltransferase
E3S77_RS04845	COG3679	Belongs to the UPF0342 family
E3S77_RS04875	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3S77_RS04880	COG0772	Belongs to the SEDS family
E3S77_RS04890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E3S77_RS04910	COG0483	inositol monophosphate 1-phosphatase activity
E3S77_RS04935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3S77_RS04940	COG1177	transmembrane transport
E3S77_RS04945	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3S77_RS05010	COG0569	domain protein
E3S77_RS05015	COG1294	oxidase, subunit
E3S77_RS05020	COG1271	oxidase subunit
E3S77_RS05025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3S77_RS05045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3S77_RS05060	COG4721	ABC-type cobalt transport system, permease component
E3S77_RS05065	COG4172	Belongs to the ABC transporter superfamily
E3S77_RS05070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E3S77_RS05110	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3S77_RS05125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3S77_RS05170	COG1316	TRANSCRIPTIONal
E3S77_RS05180	COG2153	protein acetylation
E3S77_RS05200	COG3594	Acyltransferase
E3S77_RS05205	COG0436	Aminotransferase
E3S77_RS05210	COG3591	Belongs to the peptidase S1B family
E3S77_RS05230	COG2267	carboxylic ester hydrolase activity
E3S77_RS05240	COG1169	isochorismate synthase
E3S77_RS05250	COG1575	Belongs to the MenA family. Type 1 subfamily
E3S77_RS05260	COG2314	TM2 domain
E3S77_RS05270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S77_RS05330	COG4873	Protein conserved in bacteria
E3S77_RS05345	COG4903	ComK protein
E3S77_RS05360	COG0737	Belongs to the 5'-nucleotidase family
E3S77_RS05365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S77_RS05375	COG0861	Integral membrane protein TerC family
E3S77_RS05415	COG1115	amino acid carrier protein
E3S77_RS05420	COG0628	permease
E3S77_RS05430	COG0569	domain protein
E3S77_RS05430	COG0475	glutathione-regulated potassium exporter activity
E3S77_RS05435	COG2239	Acts as a magnesium transporter
E3S77_RS05440	COG0564	pseudouridine synthase activity
E3S77_RS05450	COG2357	RelA SpoT domain protein
E3S77_RS05465	COG2346	COG2346, Truncated hemoglobins
E3S77_RS05475	COG1164	Oligoendopeptidase f
E3S77_RS05500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S77_RS05505	COG0601	transmembrane transport
E3S77_RS05510	COG4608	Belongs to the ABC transporter superfamily
E3S77_RS05515	COG0444	Belongs to the ABC transporter superfamily
E3S77_RS05520	COG0747	negative chemotaxis
E3S77_RS05525	COG4166	transmembrane transport
E3S77_RS05530	COG4608	Belongs to the ABC transporter superfamily
E3S77_RS05535	COG0444	Belongs to the ABC transporter superfamily
E3S77_RS05540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S77_RS05545	COG0601	transmembrane transport
E3S77_RS05575	COG1881	PFAM PEBP family protein
E3S77_RS05615	COG0561	phosphatase activity
E3S77_RS05635	COG1074	ATP-dependent DNA helicase activity
E3S77_RS05655	COG0398	Pfam SNARE associated Golgi protein
E3S77_RS05675	COG0584	glycerophosphoryl diester phosphodiesterase
E3S77_RS05690	COG1902	pentaerythritol trinitrate reductase activity
E3S77_RS05695	COG1098	S1 RNA binding domain
E3S77_RS05750	COG2050	protein possibly involved in aromatic compounds catabolism
E3S77_RS05755	COG2056	Na+-H+ antiporter family
E3S77_RS05760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3S77_RS05770	COG0316	Belongs to the HesB IscA family
E3S77_RS05780	COG1252	NADH dehydrogenase
E3S77_RS05785	COG4837	Protein of unknown function (DUF1462)
E3S77_RS05790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3S77_RS05795	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E3S77_RS05805	COG1696	Membrane protein involved in D-alanine export
E3S77_RS05835	COG2445	Protein of unknown function DUF86
E3S77_RS05845	COG4470	Protein conserved in bacteria
E3S77_RS05860	COG0730	response to heat
E3S77_RS05865	COG1801	Protein of unknown function DUF72
E3S77_RS05875	COG1253	flavin adenine dinucleotide binding
E3S77_RS05895	COG1388	LysM domain
E3S77_RS05895	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S77_RS06105	COG1484	DNA-dependent DNA replication
E3S77_RS06210	COG0822	iron-sulfur transferase activity
E3S77_RS06220	COG0719	Fe-S assembly protein
E3S77_RS06225	COG0396	ATPase activity
E3S77_RS06240	COG1464	Belongs to the NlpA lipoprotein family
E3S77_RS06245	COG2011	ABC-type metal ion transport system permease component
E3S77_RS06260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S77_RS06265	COG3878	Protein conserved in bacteria
E3S77_RS06280	COG1393	Belongs to the ArsC family
E3S77_RS06285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S77_RS06310	COG1279	arginine transmembrane transporter activity
E3S77_RS06315	COG0406	alpha-ribazole phosphatase activity
E3S77_RS06355	COG1278	Cold shock
E3S77_RS06415	COG0557	exoribonuclease II activity
E3S77_RS06420	COG1647	Serine aminopeptidase, S33
E3S77_RS06425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S77_RS06475	COG0281	malic enzyme
E3S77_RS06490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3S77_RS06545	COG3942	CHAP domain
E3S77_RS06545	COG1388	LysM domain
E3S77_RS06575	COG1040	competence protein
E3S77_RS06580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E3S77_RS06590	COG1739	Uncharacterized protein family UPF0029
E3S77_RS06595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3S77_RS06650	COG4607	ABC-type enterochelin transport system periplasmic component
E3S77_RS06655	COG4604	ABC transporter, ATP-binding protein
E3S77_RS06660	COG4605	iron ion homeostasis
E3S77_RS06665	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S77_RS06675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S77_RS06680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S77_RS06700	COG3104	oligopeptide transport
E3S77_RS06720	COG1174	glycine betaine transport
E3S77_RS06725	COG1125	glycine betaine transport
E3S77_RS06725	COG0517	IMP dehydrogenase activity
E3S77_RS06730	COG0514	ATP-dependent DNA helicase (RecQ)
E3S77_RS06735	COG0488	(ABC) transporter
E3S77_RS06765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S77_RS06770	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S77_RS06770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3S77_RS06780	COG0720	synthase
E3S77_RS06815	COG0463	Glycosyl transferase, family 2
E3S77_RS06820	COG0656	L-ascorbic acid biosynthetic process
E3S77_RS06825	COG1253	flavin adenine dinucleotide binding
E3S77_RS06830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3S77_RS06835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S77_RS06835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S77_RS06835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S77_RS06840	COG1105	Belongs to the carbohydrate kinase PfkB family
E3S77_RS06845	COG1349	DNA-binding transcription factor activity
E3S77_RS06850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3S77_RS06880	COG0471	metal ion transport
E3S77_RS06890	COG4989	oxidoreductase activity
E3S77_RS06895	COG0523	cobalamin synthesis protein
E3S77_RS06900	COG1846	Transcriptional regulator
E3S77_RS06905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3S77_RS06910	COG4988	ABC transporter
E3S77_RS06930	COG1611	Belongs to the LOG family
E3S77_RS06960	COG2839	Protein conserved in bacteria
E3S77_RS06975	COG0583	DNA-binding transcription factor activity
E3S77_RS07005	COG1917	Cupin 2, conserved barrel domain protein
E3S77_RS07005	COG4977	sequence-specific DNA binding
E3S77_RS07015	COG3942	CHAP domain
E3S77_RS07015	COG1388	LysM domain
E3S77_RS07020	COG0306	phosphate transporter
E3S77_RS07025	COG1392	Phosphate transport regulator
E3S77_RS07030	COG0577	efflux transmembrane transporter activity
E3S77_RS07035	COG1136	(ABC) transporter
E3S77_RS07070	COG3949	Membrane
E3S77_RS07085	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E3S77_RS07095	COG2376	Dihydroxyacetone kinase
E3S77_RS07100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S77_RS07105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S77_RS07110	COG1120	ATPase activity
E3S77_RS07115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E3S77_RS07125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S77_RS07130	COG1132	(ABC) transporter
E3S77_RS07135	COG1686	Belongs to the peptidase S11 family
E3S77_RS07140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3S77_RS07150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S77_RS07155	COG1682	transport, permease protein
E3S77_RS07165	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
E3S77_RS07175	COG1321	iron dependent repressor
E3S77_RS07180	COG1121	(ABC) transporter
E3S77_RS07185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S77_RS07190	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S77_RS07235	COG4974	Belongs to the 'phage' integrase family
E3S77_RS07260	COG2267	carboxylic ester hydrolase activity
E3S77_RS07285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S77_RS07290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S77_RS07325	COG1078	dGTPase activity
E3S77_RS07335	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S77_RS07340	COG0667	Aldo Keto reductase
E3S77_RS07380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S77_RS07400	COG0083	homoserine kinase activity
E3S77_RS07405	COG0095	Lipoate-protein ligase
E3S77_RS07510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3S77_RS07540	COG3266	domain, Protein
E3S77_RS07540	COG4932	domain protein
E3S77_RS07550	COG0561	phosphatase activity
E3S77_RS07560	COG1428	Deoxynucleoside kinase
E3S77_RS07565	COG1428	Deoxynucleoside kinase
E3S77_RS07570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3S77_RS07600	COG1473	amidohydrolase
E3S77_RS07630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E3S77_RS07640	COG2813	Specifically methylates the guanine in position
E3S77_RS07670	COG0250	Participates in transcription elongation, termination and antitermination
E3S77_RS07675	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S77_RS07700	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3S77_RS07720	COG4956	integral membrane protein (PIN domain superfamily)
E3S77_RS07725	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3S77_RS07740	COG3880	PFAM UvrB UvrC protein
E3S77_RS07750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S77_RS07765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S77_RS07860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3S77_RS07885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3S77_RS07900	COG1098	S1 RNA binding domain
E3S77_RS07910	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3S77_RS07915	COG3956	TIGRFAM MazG family protein
E3S77_RS07920	COG2244	polysaccharide biosynthetic process
E3S77_RS07960	COG0251	oxidation-reduction process
E3S77_RS07965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3S77_RS07975	COG4466	Protein conserved in bacteria
E3S77_RS07985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S77_RS07990	COG0084	hydrolase, TatD family'
E3S77_RS08000	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3S77_RS08010	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3S77_RS08020	COG1774	PSP1 C-terminal conserved region
E3S77_RS08025	COG0470	DNA polymerase III
E3S77_RS08030	COG3870	Protein conserved in bacteria
E3S77_RS08040	COG1982	Orn Lys Arg decarboxylase major
E3S77_RS08070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E3S77_RS08075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3S77_RS08095	COG2188	Transcriptional regulator
E3S77_RS08100	COG0366	Alpha amylase catalytic
E3S77_RS08105	COG1263	PTS System
E3S77_RS08105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S77_RS08115	COG0493	'glutamate synthase
E3S77_RS08120	COG0069	glutamate synthase activity
E3S77_RS08120	COG0070	glutamate synthase
E3S77_RS08120	COG0067	glutamate synthase
E3S77_RS08125	COG0583	DNA-binding transcription factor activity
E3S77_RS08160	COG1464	Belongs to the NlpA lipoprotein family
E3S77_RS08165	COG2011	ABC-type metal ion transport system permease component
E3S77_RS08175	COG0626	cystathionine gamma-synthase activity
E3S77_RS08180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3S77_RS08185	COG0733	neurotransmitter:sodium symporter activity
E3S77_RS08195	COG1647	Serine aminopeptidase, S33
E3S77_RS08210	COG5609	conserved protein (DUF2294)
E3S77_RS08220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3S77_RS08245	COG0523	cobalamin synthesis protein
E3S77_RS08375	COG3759	membrane
E3S77_RS08380	COG1683	Conserved Protein
E3S77_RS08420	COG2233	PERMEase
E3S77_RS08450	COG1823	symporter activity
E3S77_RS08555	COG0012	GTP binding
E3S77_RS08560	COG4481	Protein conserved in bacteria
E3S77_RS08565	COG0668	transmembrane transport
E3S77_RS08570	COG1475	DNA binding
E3S77_RS08575	COG0626	cystathionine gamma-synthase activity
E3S77_RS08580	COG0626	cystathionine gamma-synthase activity
E3S77_RS08585	COG0646	methionine synthase
E3S77_RS08585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3S77_RS08615	COG1131	(ABC) transporter
E3S77_RS08625	COG1476	TRANSCRIPTIONal
E3S77_RS08635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3S77_RS08640	COG0805	protein transport
E3S77_RS08645	COG0672	)-iron permease
E3S77_RS08650	COG2837	iron assimilation
E3S77_RS08655	COG2822	iron ion transport
E3S77_RS08660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S77_RS08670	COG0431	NADPH-dependent FMN reductase
E3S77_RS08675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S77_RS08680	COG0346	lactoylglutathione lyase activity
E3S77_RS08685	COG2271	Major facilitator Superfamily
E3S77_RS08710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S77_RS08720	COG3037	sugar-specific permease SgaT UlaA
E3S77_RS08745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S77_RS08795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3S77_RS08800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S77_RS08830	COG0577	efflux transmembrane transporter activity
E3S77_RS08835	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E3S77_RS08840	COG1114	Component of the transport system for branched-chain amino acids
E3S77_RS08940	COG0842	Transport permease protein
E3S77_RS08940	COG1511	domain protein
E3S77_RS08950	COG3942	CHAP domain
E3S77_RS08950	COG1388	LysM domain
E3S77_RS08975	COG0739	heme binding
E3S77_RS09030	COG2226	methyltransferase
E3S77_RS09035	COG2723	6-phospho-beta-galactosidase activity
E3S77_RS09045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S77_RS09085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S77_RS09090	COG1063	alcohol dehydrogenase
E3S77_RS09100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S77_RS09105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S77_RS09110	COG1063	alcohol dehydrogenase
E3S77_RS09115	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E3S77_RS09120	COG1063	alcohol dehydrogenase
E3S77_RS09130	COG1063	alcohol dehydrogenase
E3S77_RS09135	COG3775	system Galactitol-specific IIC component
E3S77_RS09140	COG3414	Phosphotransferase system galactitol-specific IIB component
E3S77_RS09160	COG1957	nucleoside hydrolase
E3S77_RS09165	COG1263	PTS System
E3S77_RS09165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S77_RS09165	COG2190	(PTS) system
E3S77_RS09190	COG3189	MarR family transcriptional regulator
E3S77_RS09195	COG0747	negative chemotaxis
E3S77_RS09210	COG0318	PFAM AMP-dependent synthetase and ligase
E3S77_RS09215	COG1960	acyl-CoA dehydrogenase activity
E3S77_RS09225	COG0183	Belongs to the thiolase family
E3S77_RS09280	COG1755	Isoprenylcysteine carboxyl methyltransferase
E3S77_RS09290	COG0673	inositol 2-dehydrogenase activity
E3S77_RS09295	COG0673	inositol 2-dehydrogenase activity
E3S77_RS09300	COG3833	ABC-type maltose transport systems, permease component
E3S77_RS09305	COG1175	transmembrane transport
E3S77_RS09315	COG3842	ATPase activity
E3S77_RS09330	COG0405	Gamma-glutamyltransferase
E3S77_RS09340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S77_RS09380	COG1737	Transcriptional regulator
E3S77_RS09410	COG3961	Belongs to the TPP enzyme family
E3S77_RS09415	COG1335	isochorismatase
E3S77_RS09420	COG1114	Component of the transport system for branched-chain amino acids
E3S77_RS09465	COG1960	acyl-CoA dehydrogenase activity
E3S77_RS09470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3S77_RS09505	COG2832	Protein of unknown function (DUF454)
E3S77_RS09515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S77_RS09520	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3S77_RS09530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S77_RS09560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S77_RS09570	COG1086	Polysaccharide biosynthesis protein
E3S77_RS09595	COG1454	alcohol dehydrogenase
E3S77_RS09595	COG1012	belongs to the aldehyde dehydrogenase family
E3S77_RS09610	COG0737	Belongs to the 5'-nucleotidase family
E3S77_RS09630	COG3639	organic phosphonate transmembrane transporter activity
E3S77_RS09655	COG2814	Major facilitator Superfamily
E3S77_RS09660	COG0813	purine-nucleoside phosphorylase activity
E3S77_RS09685	COG0438	transferase activity, transferring glycosyl groups
E3S77_RS09690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S77_RS09695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3S77_RS09720	COG1475	DNA binding
E3S77_RS09725	COG0019	diaminopimelate decarboxylase activity
E3S77_RS09735	COG4264	IucA IucC family
E3S77_RS09740	COG4264	IucA IucC family
E3S77_RS09745	COG2814	Major facilitator Superfamily
E3S77_RS09750	COG4264	IucA IucC family
E3S77_RS09755	COG2423	ornithine cyclodeaminase activity
E3S77_RS09765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S77_RS09770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S77_RS09775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S77_RS09790	COG1620	l-lactate permease
E3S77_RS09805	COG0697	spore germination
E3S77_RS09810	COG4716	Myosin-crossreactive antigen
E3S77_RS09815	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3S77_RS09825	COG1473	amidohydrolase
E3S77_RS09840	COG0823	Involved in the tonB-independent uptake of proteins
E3S77_RS09855	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S77_RS09890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S77_RS09895	COG2210	Belongs to the sulfur carrier protein TusA family
E3S77_RS09900	COG1937	Protein conserved in bacteria
E3S77_RS09905	COG0730	response to heat
E3S77_RS09955	COG0737	Belongs to the 5'-nucleotidase family
E3S77_RS09960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3S77_RS09970	COG4863	YycH protein
E3S77_RS10000	COG0305	Participates in initiation and elongation during chromosome replication
E3S77_RS10010	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E3S77_RS10020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3S77_RS10045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3S77_RS10065	COG2501	S4 domain
E3S77_RS10105	COG1475	DNA binding
E3S77_RS10130	COG1278	Cold shock
E3S77_RS10140	COG0577	efflux transmembrane transporter activity
E3S77_RS10145	COG1136	(ABC) transporter
E3S77_RS10160	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3S77_RS10170	COG2962	Rard protein
E3S77_RS10175	COG0471	metal ion transport
E3S77_RS10230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3S77_RS10285	COG1215	transferase activity, transferring glycosyl groups
E3S77_RS10290	COG1309	transcriptional regulator
E3S77_RS10320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S77_RS10340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S77_RS10350	COG0201	protein transport
E3S77_RS10360	COG1073	alpha beta
E3S77_RS10375	COG0438	transferase activity, transferring glycosyl groups
E3S77_RS10390	COG3433	isochorismatase activity
E3S77_RS10390	COG1535	isochorismatase
E3S77_RS10400	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3S77_RS10400	COG3942	CHAP domain
E3S77_RS10410	COG1482	cell wall glycoprotein biosynthetic process
E3S77_RS10415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S77_RS10415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S77_RS10415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S77_RS10420	COG3711	transcriptional antiterminator
E3S77_RS10420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S77_RS10450	COG2235	arginine
E3S77_RS10475	COG4932	domain protein
E3S77_RS10475	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E3S77_RS10475	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E3S77_RS10475	COG4932	domain protein
E3S77_RS10485	COG1846	Transcriptional regulator
E3S77_RS10495	COG1785	Belongs to the alkaline phosphatase family
E3S77_RS10505	COG0745	RESPONSE REGULATOR receiver
E3S77_RS10510	COG2205	protein histidine kinase activity
E3S77_RS10515	COG1136	(ABC) transporter
E3S77_RS10535	COG0386	Belongs to the glutathione peroxidase family
E3S77_RS10545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3S77_RS10555	COG2851	Citrate transporter
E3S77_RS10580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S77_RS10585	COG1510	regulation of RNA biosynthetic process
E3S77_RS10615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S77_RS10645	COG0531	amino acid
E3S77_RS10655	COG3527	Alpha-acetolactate decarboxylase
E3S77_RS10660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S77_RS10720	COG0167	dihydroorotate dehydrogenase activity
E3S77_RS10870	COG0436	Aminotransferase
E3S77_RS10885	COG2217	Heavy metal translocating P-type atpase
E3S77_RS10915	COG2409	Drug exporters of the RND superfamily
E3S77_RS10940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3S77_RS10950	COG3425	synthase
E3S77_RS10960	COG3942	CHAP domain
E3S77_RS10970	COG0583	DNA-binding transcription factor activity
E3S77_RS10980	COG1346	cytolysis
E3S77_RS10985	COG0028	Belongs to the TPP enzyme family
E3S77_RS11010	COG0697	spore germination
E3S77_RS11025	COG1760	l-serine dehydratase
E3S77_RS11030	COG1760	l-serine dehydratase
E3S77_RS11050	COG3764	Sortase (surface protein transpeptidase)
E3S77_RS11060	COG1131	(ABC) transporter
E3S77_RS11065	COG0561	phosphatase activity
E3S77_RS11080	COG2514	catechol 2,3-dioxygenase activity
E3S77_RS11090	COG1846	Transcriptional regulator
E3S77_RS11095	COG0346	lactoylglutathione lyase activity
E3S77_RS11100	COG0400	carboxylic ester hydrolase activity
E3S77_RS11120	COG1131	(ABC) transporter
E3S77_RS11125	COG1846	Transcriptional regulator
E3S77_RS11130	COG2814	Major facilitator Superfamily
E3S77_RS11140	COG0586	Pfam SNARE associated Golgi protein
E3S77_RS11145	COG2271	Major facilitator Superfamily
E3S77_RS11155	COG4876	unkown
E3S77_RS11160	COG2357	RelA SpoT domain protein
E3S77_RS11165	COG0789	Transcriptional regulator
E3S77_RS11170	COG1802	Transcriptional regulator
E3S77_RS11175	COG1070	Carbohydrate kinase
E3S77_RS11295	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3S77_RS11300	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3S77_RS11305	COG1028	Short-chain dehydrogenase reductase Sdr
E3S77_RS11310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3S77_RS11330	COG0747	negative chemotaxis
E3S77_RS11335	COG0601	transmembrane transport
E3S77_RS11340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S77_RS11350	COG1124	(ABC) transporter
E3S77_RS11365	COG0069	glutamate synthase activity
E3S77_RS11370	COG4808	Protein conserved in bacteria
E3S77_RS11385	COG1363	Peptidase, m42
E3S77_RS11390	COG4619	ABC transporter
E3S77_RS11395	COG0390	transport system, permease component
E3S77_RS11400	COG2814	Major facilitator Superfamily
E3S77_RS11405	COG2272	Belongs to the type-B carboxylesterase lipase family
E3S77_RS11410	COG0531	amino acid
E3S77_RS11415	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E3S77_RS11435	COG1174	glycine betaine transport
E3S77_RS11445	COG1174	glycine betaine transport
E3S77_RS11455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S77_RS11470	COG0531	amino acid
E3S77_RS11480	COG1113	amino acid transport
E3S77_RS11500	COG2814	Major facilitator Superfamily
E3S77_RS11510	COG1929	Belongs to the glycerate kinase type-1 family
E3S77_RS11530	COG1132	(ABC) transporter
E3S77_RS11540	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3S77_RS11545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3S77_RS11555	COG0156	8-amino-7-oxononanoate synthase activity
E3S77_RS11595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E3S77_RS11610	COG2814	Major facilitator Superfamily
E3S77_RS11615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3S77_RS11620	COG0765	amino acid transport
E3S77_RS11625	COG1126	abc transporter atp-binding protein
E3S77_RS11645	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3S77_RS11645	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S77_RS11660	COG2116	formate transmembrane transporter activity
E3S77_RS11665	COG0454	-acetyltransferase
E3S77_RS11675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3S77_RS11680	COG2146	nitrite reductase [NAD(P)H] activity
E3S77_RS11690	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3S77_RS11695	COG1140	nitrate reductase beta subunit
E3S77_RS11705	COG2181	nitrate reductase activity
E3S77_RS11725	COG0789	Transcriptional regulator
E3S77_RS11765	COG3871	stress protein (general stress protein 26)
E3S77_RS11780	COG1263	PTS System
E3S77_RS11780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S77_RS11795	COG1511	domain protein
E3S77_RS11820	COG0604	alcohol dehydrogenase
E3S77_RS11840	COG1620	l-lactate permease
E3S77_RS11910	COG1566	PFAM secretion protein HlyD family protein
E3S77_RS11915	COG2814	Major facilitator Superfamily
E3S77_RS11925	COG0657	acetylesterase activity
E3S77_RS11940	COG0598	Magnesium transport protein CorA
E3S77_RS11950	COG0786	glutamate:sodium symporter activity
E3S77_RS11960	COG3152	Membrane
E3S77_RS11965	COG4152	abc transporter atp-binding protein
E3S77_RS11970	COG1668	transmembrane transport
E3S77_RS11990	COG2258	MOSC domain
E3S77_RS12015	COG0583	DNA-binding transcription factor activity
E3S77_RS12030	COG1473	amidohydrolase
E3S77_RS12035	COG1028	Short-chain dehydrogenase reductase Sdr
E3S77_RS12055	COG1737	Transcriptional regulator
E3S77_RS12060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S77_RS12060	COG1263	PTS System
E3S77_RS12070	COG0385	Bile acid
E3S77_RS12075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3S77_RS12095	COG1113	amino acid transport
E3S77_RS12175	COG1757	Na H antiporter
E3S77_RS12245	COG4413	Urea transporter
E3S77_RS12250	COG1960	acyl-CoA dehydrogenase activity
E3S77_RS12265	COG1268	BioY protein
E3S77_RS12280	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3S77_RS12285	COG4149	molybdate abc transporter
E3S77_RS12290	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3S77_RS12295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3S77_RS12315	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3S77_RS12375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3S77_RS12420	COG2252	PERMEase
E3S77_RS12535	COG0201	protein transport
E3S77_RS12620	COG0028	Belongs to the TPP enzyme family
E3S77_RS12625	COG3527	Alpha-acetolactate decarboxylase
E3S77_RS12635	COG0693	protein deglycase activity
E3S77_RS12640	COG2378	regulation of single-species biofilm formation
E3S77_RS12645	COG5492	domain, Protein
E3S77_RS12660	COG0656	L-ascorbic acid biosynthetic process
E3S77_RS12730	COG2130	NADP-dependent
E3S77_RS12740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S77_RS12765	COG2814	Major facilitator Superfamily
E3S77_RS12770	COG4264	IucA IucC family
E3S77_RS12775	COG3457	Alanine racemase
E3S77_RS12785	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S77_RS12790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S77_RS12795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S77_RS12810	COG1988	membrane-bound metal-dependent
E3S77_RS12820	COG1272	protein, Hemolysin III
E3S77_RS12835	COG2814	Major facilitator Superfamily
E3S77_RS12840	COG0489	protein tyrosine kinase activity
E3S77_RS12895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E3S77_RS12925	COG3711	transcriptional antiterminator
E3S77_RS12940	COG1119	ATPase activity
E3S77_RS12945	COG0561	phosphatase activity
E3S77_RS12975	COG0640	Transcriptional regulator
E3S77_RS12980	COG0702	epimerase
E3S77_RS12985	COG1482	cell wall glycoprotein biosynthetic process
E3S77_RS13005	COG0783	Belongs to the Dps family
E3S77_RS13010	COG0813	purine-nucleoside phosphorylase activity
E3S77_RS13055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S77_RS13095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3S77_RS13115	COG2890	protein-(glutamine-N5) methyltransferase activity
E3S77_RS13120	COG0009	L-threonylcarbamoyladenylate synthase
E3S77_RS13145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S77_RS13220	COG0629	single-stranded DNA binding
E3S77_RS13260	COG1418	mRNA catabolic process
E3S77_RS13270	COG1937	Protein conserved in bacteria
E3S77_RS13285	COG0772	Belongs to the SEDS family
E3S77_RS13295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3S77_RS13305	COG0745	RESPONSE REGULATOR receiver
E3S77_RS13310	COG2205	protein histidine kinase activity
E3S77_RS13340	COG3428	Bacterial PH domain
E3S77_RS13355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E3S77_RS13370	COG2208	phosphoserine phosphatase activity
E3S77_RS13375	COG1366	Belongs to the anti-sigma-factor antagonist family
E3S77_RS13385	COG1191	sigma factor activity
E3S77_RS13390	COG2183	response to ionizing radiation
E3S77_RS13460	COG0028	Belongs to the TPP enzyme family
E3S77_RS13475	COG0802	atpase or kinase
E3S77_RS13480	COG1214	PFAM Peptidase M22, glycoprotease
E3S77_RS13485	COG0456	acetyltransferase
E3S77_RS13495	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E3S77_RS13505	COG0488	(ABC) transporter
E3S77_RS13515	COG2391	methyltransferase activity
E3S77_RS13520	COG0425	Belongs to the sulfur carrier protein TusA family
E3S77_RS13525	COG0004	ammonium transporteR
E3S77_RS13530	COG1609	Transcriptional regulator
E3S77_RS13535	COG1621	beta-fructofuranosidase activity
E3S77_RS13540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3S77_RS13605	COG0582	viral genome integration into host DNA
E3S77_RS13680	COG2826	transposase and inactivated derivatives, IS30 family
E3S77_RS13710	COG1674	ftsk spoiiie
E3S77_RS13715	COG0433	COG0433 Predicted ATPase
E3S77_RS13735	COG2946	Replication initiation factor
E3S77_RS13775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S77_RS13780	COG0156	8-amino-7-oxononanoate synthase activity
E3S77_RS13925	COG1484	DNA-dependent DNA replication