locus-tag	class	description
E3S87_RS00020	COG0740	serine-type endopeptidase activity
E3S87_RS00070	COG0739	heme binding
E3S87_RS00120	COG1388	LysM domain
E3S87_RS00120	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S87_RS00130	COG1388	LysM domain
E3S87_RS00130	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S87_RS00185	COG1725	Transcriptional regulator
E3S87_RS00200	COG1131	(ABC) transporter
E3S87_RS00250	COG1012	belongs to the aldehyde dehydrogenase family
E3S87_RS00265	COG1335	isochorismatase
E3S87_RS00285	COG0077	Prephenate dehydratase
E3S87_RS00295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3S87_RS00330	COG4496	protein, YerC YecD
E3S87_RS00350	COG4851	CamS sex pheromone cAM373 precursor
E3S87_RS00465	COG1295	ribonuclease BN
E3S87_RS00485	COG2309	aminopeptidase activity
E3S87_RS00490	COG1607	acyl-coa hydrolase
E3S87_RS00495	COG0535	radical SAM domain protein
E3S87_RS00525	COG1388	LysM domain
E3S87_RS00525	COG1134	teichoic acid transport
E3S87_RS00535	COG1988	membrane-bound metal-dependent
E3S87_RS00540	COG1194	a g-specific adenine glycosylase
E3S87_RS00555	COG4129	membrane
E3S87_RS00565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3S87_RS00570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S87_RS00735	COG0765	amino acid transport
E3S87_RS00740	COG1126	abc transporter atp-binding protein
E3S87_RS00745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3S87_RS00775	COG0564	pseudouridine synthase activity
E3S87_RS00780	COG2203	Gaf domain
E3S87_RS00780	COG4585	Histidine kinase
E3S87_RS00785	COG2197	response regulator
E3S87_RS00805	COG0420	3'-5' exonuclease activity
E3S87_RS00835	COG0537	adenosine 5'-monophosphoramidase activity
E3S87_RS00840	COG1131	(ABC) transporter
E3S87_RS01050	COG5492	domain, Protein
E3S87_RS01140	COG2816	NAD+ diphosphatase activity
E3S87_RS01145	COG1506	peptidase
E3S87_RS01165	COG0656	L-ascorbic acid biosynthetic process
E3S87_RS01175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E3S87_RS01185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3S87_RS01220	COG3266	domain, Protein
E3S87_RS01220	COG4193	domain, Protein
E3S87_RS01220	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S87_RS01240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S87_RS01240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S87_RS01270	COG2267	carboxylic ester hydrolase activity
E3S87_RS01275	COG1846	Transcriptional regulator
E3S87_RS01280	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3S87_RS01285	COG1242	4 iron, 4 sulfur cluster binding
E3S87_RS01290	COG2814	Major facilitator Superfamily
E3S87_RS01310	COG2081	HI0933 family
E3S87_RS01315	COG2244	polysaccharide biosynthetic process
E3S87_RS01320	COG1187	pseudouridine synthase activity
E3S87_RS01340	COG0510	thiamine kinase activity
E3S87_RS01380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S87_RS01390	COG1363	Peptidase, m42
E3S87_RS01395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S87_RS01405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3S87_RS01410	COG1674	ftsk spoiiie
E3S87_RS01435	COG1605	Chorismate mutase
E3S87_RS01435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E3S87_RS01455	COG0454	-acetyltransferase
E3S87_RS01460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S87_RS01490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3S87_RS01495	COG0204	Acyl-transferase
E3S87_RS01500	COG1263	PTS System
E3S87_RS01500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S87_RS01515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S87_RS01520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E3S87_RS01525	COG1764	response to oxidative stress
E3S87_RS01530	COG0584	glycerophosphoryl diester phosphodiesterase
E3S87_RS01545	COG1956	GAF domain-containing protein
E3S87_RS01560	COG1104	cysteine desulfurase activity
E3S87_RS01570	COG0730	response to heat
E3S87_RS01580	COG0827	DNA restriction-modification system
E3S87_RS01620	COG4109	DRTGG domain
E3S87_RS01625	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3S87_RS01635	COG0281	malic enzyme
E3S87_RS01660	COG1113	amino acid transport
E3S87_RS01665	COG0372	Belongs to the citrate synthase family
E3S87_RS01675	COG0745	RESPONSE REGULATOR receiver
E3S87_RS01680	COG5002	protein histidine kinase activity
E3S87_RS01690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S87_RS01690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S87_RS01695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3S87_RS01720	COG1484	DNA-dependent DNA replication
E3S87_RS01735	COG0833	amino acid
E3S87_RS01755	COG4112	unkown
E3S87_RS01790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3S87_RS01805	COG0113	porphobilinogen synthase activity
E3S87_RS01845	COG0285	dihydrofolate synthase activity
E3S87_RS01850	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E3S87_RS01895	COG2868	ribosomal protein
E3S87_RS01935	COG1862	Preprotein translocase
E3S87_RS01940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S87_RS01940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S87_RS01945	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E3S87_RS01945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3S87_RS01990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3S87_RS01995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3S87_RS02000	COG1959	2 iron, 2 sulfur cluster binding
E3S87_RS02015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S87_RS02020	COG1104	cysteine desulfurase activity
E3S87_RS02035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3S87_RS02085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3S87_RS02090	COG1984	allophanate hydrolase subunit 2
E3S87_RS02095	COG0511	ligase activity, forming carbon-carbon bonds
E3S87_RS02100	COG0439	Biotin carboxylase
E3S87_RS02110	COG1914	H( )-stimulated, divalent metal cation uptake system
E3S87_RS02135	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E3S87_RS02140	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E3S87_RS02150	COG1534	Rna-binding protein
E3S87_RS02160	COG1713	HD superfamily hydrolase involved in NAD metabolism
E3S87_RS02165	COG0799	negative regulation of ribosome biogenesis
E3S87_RS02170	COG2226	methyltransferase
E3S87_RS02180	COG2131	deaminase
E3S87_RS02185	COG0658	competence protein
E3S87_RS02185	COG2333	competence protein COMEC
E3S87_RS02190	COG1466	dna polymerase III delta subunit
E3S87_RS02205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3S87_RS02235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3S87_RS02240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3S87_RS02250	COG1030	water channel activity
E3S87_RS02265	COG1702	phosphate starvation-inducible protein PhoH
E3S87_RS02280	COG0295	cytidine deaminase activity
E3S87_RS02300	COG0517	IMP dehydrogenase activity
E3S87_RS02315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3S87_RS02320	COG2384	SAM-dependent methyltransferase
E3S87_RS02330	COG0513	Belongs to the DEAD box helicase family
E3S87_RS02340	COG1121	(ABC) transporter
E3S87_RS02345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S87_RS02350	COG0735	belongs to the Fur family
E3S87_RS02370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3S87_RS02380	COG4483	Protein conserved in bacteria
E3S87_RS02385	COG1940	carbohydrate kinase activity
E3S87_RS02390	COG0011	TIGRFAM Protein of
E3S87_RS02395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S87_RS02400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3S87_RS02405	COG1459	type II secretion system
E3S87_RS02410	COG4537	Required for transformation and DNA binding
E3S87_RS02455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3S87_RS02460	COG0095	Lipoate-protein ligase
E3S87_RS02475	COG0006	proline dipeptidase activity
E3S87_RS02485	COG0511	ligase activity, forming carbon-carbon bonds
E3S87_RS02490	COG0439	Biotin carboxylase
E3S87_RS02495	COG1302	Protein conserved in bacteria
E3S87_RS02525	COG0497	DNA recombination
E3S87_RS02530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S87_RS02535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E3S87_RS02540	COG0022	dehydrogenase e1 component
E3S87_RS02545	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3S87_RS02555	COG4129	membrane
E3S87_RS02565	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3S87_RS02595	COG1609	Transcriptional regulator
E3S87_RS02600	COG0366	Alpha amylase catalytic
E3S87_RS02610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3S87_RS02625	COG4221	oxidoreductase activity
E3S87_RS02635	COG0667	Aldo Keto reductase
E3S87_RS02640	COG0494	nUDIX hydrolase
E3S87_RS02645	COG0735	belongs to the Fur family
E3S87_RS02670	COG1187	pseudouridine synthase activity
E3S87_RS02675	COG0745	RESPONSE REGULATOR receiver
E3S87_RS02715	COG1141	Ferredoxin
E3S87_RS02725	COG0514	ATP-dependent DNA helicase (RecQ)
E3S87_RS02740	COG0492	ferredoxin-NADP+ reductase activity
E3S87_RS02795	COG0142	geranyltranstransferase activity
E3S87_RS02830	COG4347	Protein of unknown function (DUF1405)
E3S87_RS02835	COG2738	Putative neutral zinc metallopeptidase
E3S87_RS02845	COG0438	transferase activity, transferring glycosyl groups
E3S87_RS02870	COG3935	DnaD domain protein
E3S87_RS02875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3S87_RS02885	COG4499	WXG100 protein secretion system (Wss), protein YukC
E3S87_RS02885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3S87_RS02915	COG0116	Belongs to the methyltransferase superfamily
E3S87_RS02930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3S87_RS02935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S87_RS02950	COG0531	amino acid
E3S87_RS02970	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3S87_RS03030	COG2826	transposase and inactivated derivatives, IS30 family
E3S87_RS03050	COG0671	phosphoesterase, PA-phosphatase related
E3S87_RS03100	COG4548	von Willebrand factor, type A
E3S87_RS03170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3S87_RS03175	COG0527	aspartate kinase activity
E3S87_RS03180	COG0488	(ABC) transporter
E3S87_RS03195	COG0573	inorganic phosphate transmembrane transporter activity
E3S87_RS03200	COG0581	inorganic phosphate transmembrane transporter activity
E3S87_RS03210	COG0704	Plays a role in the regulation of phosphate uptake
E3S87_RS03260	COG2348	transferase activity, transferring amino-acyl groups
E3S87_RS03295	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S87_RS03300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S87_RS03305	COG1363	Peptidase, m42
E3S87_RS03315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3S87_RS03330	COG1316	TRANSCRIPTIONal
E3S87_RS03335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3S87_RS03345	COG0628	permease
E3S87_RS03360	COG1115	amino acid carrier protein
E3S87_RS03370	COG0187	DNA topoisomerase II activity
E3S87_RS03385	COG0824	Thioesterase
E3S87_RS03395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S87_RS03415	COG4846	Membrane protein involved in cytochrome C biogenesis
E3S87_RS03480	COG0833	amino acid
E3S87_RS03505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3S87_RS03510	COG0460	homoserine dehydrogenase
E3S87_RS03515	COG0527	aspartate kinase activity
E3S87_RS03530	COG1525	nuclease
E3S87_RS03540	COG2197	response regulator
E3S87_RS03555	COG1131	(ABC) transporter
E3S87_RS03670	COG2826	transposase and inactivated derivatives, IS30 family
E3S87_RS03710	COG2946	Replication initiation factor
E3S87_RS03730	COG0433	COG0433 Predicted ATPase
E3S87_RS03735	COG1674	ftsk spoiiie
E3S87_RS03765	COG2826	transposase and inactivated derivatives, IS30 family
E3S87_RS03780	COG0789	Transcriptional regulator
E3S87_RS03785	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E3S87_RS03800	COG1923	regulation of RNA biosynthetic process
E3S87_RS03825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3S87_RS03830	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3S87_RS03865	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3S87_RS03870	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3S87_RS03870	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3S87_RS03875	COG1692	metallophosphoesterase
E3S87_RS03895	COG1058	Belongs to the CinA family
E3S87_RS03895	COG1546	Belongs to the CinA family
E3S87_RS03915	COG0300	oxidoreductase activity
E3S87_RS03920	COG0612	Peptidase, M16
E3S87_RS03925	COG0612	Peptidase, M16
E3S87_RS03930	COG2188	Transcriptional regulator
E3S87_RS03955	COG0196	riboflavin kinase activity
E3S87_RS03980	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E3S87_RS03985	COG0195	Participates in both transcription termination and antitermination
E3S87_RS04080	COG0758	DNA mediated transformation
E3S87_RS04085	COG2348	transferase activity, transferring amino-acyl groups
E3S87_RS04140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3S87_RS04150	COG0552	protein localization to endoplasmic reticulum
E3S87_RS04155	COG1196	nuclear chromosome segregation
E3S87_RS04200	COG1302	Protein conserved in bacteria
E3S87_RS04215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3S87_RS04230	COG0631	protein serine/threonine phosphatase activity
E3S87_RS04240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3S87_RS04240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3S87_RS04255	COG2314	TM2 domain
E3S87_RS04265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3S87_RS04270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3S87_RS04330	COG2233	PERMEase
E3S87_RS04340	COG0564	pseudouridine synthase activity
E3S87_RS04350	COG2514	catechol 2,3-dioxygenase activity
E3S87_RS04365	COG3599	regulation of cell shape
E3S87_RS04370	COG2302	S4 RNA-binding domain
E3S87_RS04375	COG0762	integral membrane protein
E3S87_RS04385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3S87_RS04395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3S87_RS04425	COG4839	cell division protein FtsL
E3S87_RS04450	COG1011	Hydrolase
E3S87_RS04480	COG1288	antiporter activity
E3S87_RS04595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3S87_RS04600	COG1053	succinate dehydrogenase
E3S87_RS04605	COG2009	succinate dehydrogenase
E3S87_RS04630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3S87_RS04630	COG1796	DNA polymerase
E3S87_RS04660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3S87_RS04675	COG4509	Sortase family
E3S87_RS04730	COG0742	ribosomal rna small subunit methyltransferase
E3S87_RS04745	COG0584	glycerophosphoryl diester phosphodiesterase
E3S87_RS04750	COG3679	Belongs to the UPF0342 family
E3S87_RS04755	COG2340	Cysteine-rich secretory protein family
E3S87_RS04775	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3S87_RS04780	COG0772	Belongs to the SEDS family
E3S87_RS04790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E3S87_RS04810	COG0483	inositol monophosphate 1-phosphatase activity
E3S87_RS04835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3S87_RS04840	COG1177	transmembrane transport
E3S87_RS04845	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3S87_RS04910	COG0569	domain protein
E3S87_RS04915	COG1294	oxidase, subunit
E3S87_RS04920	COG1271	oxidase subunit
E3S87_RS04945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3S87_RS04960	COG4721	ABC-type cobalt transport system, permease component
E3S87_RS04965	COG4172	Belongs to the ABC transporter superfamily
E3S87_RS04970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E3S87_RS05010	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3S87_RS05025	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3S87_RS05070	COG1316	TRANSCRIPTIONal
E3S87_RS05100	COG3594	Acyltransferase
E3S87_RS05105	COG0436	Aminotransferase
E3S87_RS05130	COG2267	carboxylic ester hydrolase activity
E3S87_RS05140	COG1169	isochorismate synthase
E3S87_RS05150	COG1575	Belongs to the MenA family. Type 1 subfamily
E3S87_RS05155	COG0456	acetyltransferase
E3S87_RS05160	COG2314	TM2 domain
E3S87_RS05170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S87_RS05230	COG4873	Protein conserved in bacteria
E3S87_RS05245	COG4903	ComK protein
E3S87_RS05260	COG0737	Belongs to the 5'-nucleotidase family
E3S87_RS05265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S87_RS05275	COG0861	Integral membrane protein TerC family
E3S87_RS05325	COG1115	amino acid carrier protein
E3S87_RS05330	COG0628	permease
E3S87_RS05340	COG0475	glutathione-regulated potassium exporter activity
E3S87_RS05340	COG0569	domain protein
E3S87_RS05345	COG2239	Acts as a magnesium transporter
E3S87_RS05350	COG0564	pseudouridine synthase activity
E3S87_RS05360	COG2357	RelA SpoT domain protein
E3S87_RS05375	COG2346	COG2346, Truncated hemoglobins
E3S87_RS05385	COG1164	Oligoendopeptidase f
E3S87_RS05420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S87_RS05430	COG4608	Belongs to the ABC transporter superfamily
E3S87_RS05435	COG0444	Belongs to the ABC transporter superfamily
E3S87_RS05440	COG0747	negative chemotaxis
E3S87_RS05445	COG2826	transposase and inactivated derivatives, IS30 family
E3S87_RS05455	COG4166	transmembrane transport
E3S87_RS05460	COG4608	Belongs to the ABC transporter superfamily
E3S87_RS05465	COG0444	Belongs to the ABC transporter superfamily
E3S87_RS05470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S87_RS05475	COG0601	transmembrane transport
E3S87_RS05505	COG1881	PFAM PEBP family protein
E3S87_RS05545	COG0561	phosphatase activity
E3S87_RS05590	COG0398	Pfam SNARE associated Golgi protein
E3S87_RS05610	COG0584	glycerophosphoryl diester phosphodiesterase
E3S87_RS05630	COG1098	S1 RNA binding domain
E3S87_RS05685	COG2050	protein possibly involved in aromatic compounds catabolism
E3S87_RS05690	COG2056	Na+-H+ antiporter family
E3S87_RS05695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3S87_RS05705	COG0316	Belongs to the HesB IscA family
E3S87_RS05715	COG1252	NADH dehydrogenase
E3S87_RS05720	COG4837	Protein of unknown function (DUF1462)
E3S87_RS05725	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3S87_RS05730	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E3S87_RS05740	COG1696	Membrane protein involved in D-alanine export
E3S87_RS05770	COG2445	Protein of unknown function DUF86
E3S87_RS05780	COG4470	Protein conserved in bacteria
E3S87_RS05795	COG0730	response to heat
E3S87_RS05800	COG1801	Protein of unknown function DUF72
E3S87_RS05810	COG1253	flavin adenine dinucleotide binding
E3S87_RS05830	COG0822	iron-sulfur transferase activity
E3S87_RS05840	COG0719	Fe-S assembly protein
E3S87_RS05845	COG0396	ATPase activity
E3S87_RS05860	COG1464	Belongs to the NlpA lipoprotein family
E3S87_RS05865	COG2011	ABC-type metal ion transport system permease component
E3S87_RS05880	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S87_RS05885	COG3878	Protein conserved in bacteria
E3S87_RS05900	COG1393	Belongs to the ArsC family
E3S87_RS05905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S87_RS05930	COG1279	arginine transmembrane transporter activity
E3S87_RS05935	COG0406	alpha-ribazole phosphatase activity
E3S87_RS05975	COG1278	Cold shock
E3S87_RS06040	COG0557	exoribonuclease II activity
E3S87_RS06045	COG1647	Serine aminopeptidase, S33
E3S87_RS06050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S87_RS06100	COG0281	malic enzyme
E3S87_RS06115	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3S87_RS06170	COG1388	LysM domain
E3S87_RS06170	COG3942	CHAP domain
E3S87_RS06195	COG1040	competence protein
E3S87_RS06200	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E3S87_RS06210	COG1739	Uncharacterized protein family UPF0029
E3S87_RS06215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3S87_RS06270	COG4607	ABC-type enterochelin transport system periplasmic component
E3S87_RS06280	COG4605	iron ion homeostasis
E3S87_RS06285	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S87_RS06290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S87_RS06295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S87_RS06315	COG3104	oligopeptide transport
E3S87_RS06340	COG1174	glycine betaine transport
E3S87_RS06345	COG0517	IMP dehydrogenase activity
E3S87_RS06345	COG1125	glycine betaine transport
E3S87_RS06350	COG0514	ATP-dependent DNA helicase (RecQ)
E3S87_RS06355	COG0488	(ABC) transporter
E3S87_RS06385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S87_RS06390	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S87_RS06390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3S87_RS06400	COG0720	synthase
E3S87_RS06440	COG0463	Glycosyl transferase, family 2
E3S87_RS06445	COG0656	L-ascorbic acid biosynthetic process
E3S87_RS06450	COG1253	flavin adenine dinucleotide binding
E3S87_RS06455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3S87_RS06460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S87_RS06460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S87_RS06460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S87_RS06465	COG1105	Belongs to the carbohydrate kinase PfkB family
E3S87_RS06470	COG1349	DNA-binding transcription factor activity
E3S87_RS06475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3S87_RS06510	COG0471	metal ion transport
E3S87_RS06520	COG4989	oxidoreductase activity
E3S87_RS06525	COG0523	cobalamin synthesis protein
E3S87_RS06530	COG1846	Transcriptional regulator
E3S87_RS06535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3S87_RS06540	COG4988	ABC transporter
E3S87_RS06560	COG1611	Belongs to the LOG family
E3S87_RS06595	COG3316	Transposase and inactivated derivatives
E3S87_RS06640	COG0583	DNA-binding transcription factor activity
E3S87_RS06710	COG0577	efflux transmembrane transporter activity
E3S87_RS06710	COG1136	(ABC) transporter
E3S87_RS06755	COG3316	Transposase and inactivated derivatives
E3S87_RS06765	COG2839	Protein conserved in bacteria
E3S87_RS06770	COG2814	Major facilitator Superfamily
E3S87_RS06775	COG0583	DNA-binding transcription factor activity
E3S87_RS06815	COG1388	LysM domain
E3S87_RS06815	COG3942	CHAP domain
E3S87_RS06820	COG0306	phosphate transporter
E3S87_RS06825	COG1392	Phosphate transport regulator
E3S87_RS06830	COG0577	efflux transmembrane transporter activity
E3S87_RS06835	COG1136	(ABC) transporter
E3S87_RS06870	COG3949	Membrane
E3S87_RS06890	COG2376	Dihydroxyacetone kinase
E3S87_RS06895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S87_RS06900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S87_RS06905	COG1120	ATPase activity
E3S87_RS06910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E3S87_RS06920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S87_RS06925	COG1132	(ABC) transporter
E3S87_RS06930	COG1686	Belongs to the peptidase S11 family
E3S87_RS06935	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3S87_RS06945	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S87_RS06950	COG1682	transport, permease protein
E3S87_RS06970	COG1321	iron dependent repressor
E3S87_RS06975	COG1121	(ABC) transporter
E3S87_RS06980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S87_RS06985	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S87_RS07095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S87_RS07130	COG1078	dGTPase activity
E3S87_RS07140	COG0655	NAD(P)H dehydrogenase (quinone) activity
E3S87_RS07145	COG0667	Aldo Keto reductase
E3S87_RS07185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S87_RS07205	COG0083	homoserine kinase activity
E3S87_RS07210	COG0095	Lipoate-protein ligase
E3S87_RS07315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3S87_RS07340	COG4932	domain protein
E3S87_RS07355	COG0561	phosphatase activity
E3S87_RS07365	COG1428	Deoxynucleoside kinase
E3S87_RS07370	COG1428	Deoxynucleoside kinase
E3S87_RS07375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3S87_RS07405	COG1473	amidohydrolase
E3S87_RS07445	COG2813	Specifically methylates the guanine in position
E3S87_RS07475	COG0250	Participates in transcription elongation, termination and antitermination
E3S87_RS07480	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S87_RS07505	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3S87_RS07525	COG4956	integral membrane protein (PIN domain superfamily)
E3S87_RS07530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3S87_RS07545	COG3880	PFAM UvrB UvrC protein
E3S87_RS07555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S87_RS07575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S87_RS07670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3S87_RS07695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3S87_RS07710	COG1098	S1 RNA binding domain
E3S87_RS07720	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3S87_RS07725	COG3956	TIGRFAM MazG family protein
E3S87_RS07730	COG2244	polysaccharide biosynthetic process
E3S87_RS07770	COG0251	oxidation-reduction process
E3S87_RS07775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3S87_RS07785	COG4466	Protein conserved in bacteria
E3S87_RS07795	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S87_RS07800	COG0084	hydrolase, TatD family'
E3S87_RS07810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3S87_RS07820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3S87_RS07830	COG1774	PSP1 C-terminal conserved region
E3S87_RS07835	COG0470	DNA polymerase III
E3S87_RS07840	COG3870	Protein conserved in bacteria
E3S87_RS07850	COG1982	Orn Lys Arg decarboxylase major
E3S87_RS07880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E3S87_RS07885	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3S87_RS07905	COG2188	Transcriptional regulator
E3S87_RS07910	COG0366	Alpha amylase catalytic
E3S87_RS07915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S87_RS07915	COG1263	PTS System
E3S87_RS07925	COG0493	'glutamate synthase
E3S87_RS07930	COG0070	glutamate synthase
E3S87_RS07930	COG0067	glutamate synthase
E3S87_RS07930	COG0069	glutamate synthase activity
E3S87_RS07935	COG0583	DNA-binding transcription factor activity
E3S87_RS07970	COG1464	Belongs to the NlpA lipoprotein family
E3S87_RS07975	COG2011	ABC-type metal ion transport system permease component
E3S87_RS07985	COG0626	cystathionine gamma-synthase activity
E3S87_RS07990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3S87_RS07995	COG0733	neurotransmitter:sodium symporter activity
E3S87_RS08005	COG1647	Serine aminopeptidase, S33
E3S87_RS08020	COG5609	conserved protein (DUF2294)
E3S87_RS08030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3S87_RS08055	COG0523	cobalamin synthesis protein
E3S87_RS08190	COG3759	membrane
E3S87_RS08225	COG2233	PERMEase
E3S87_RS08255	COG1823	symporter activity
E3S87_RS08345	COG5484	DNA packaging
E3S87_RS08345	COG3728	DNA packaging
E3S87_RS08455	COG0012	GTP binding
E3S87_RS08460	COG4481	Protein conserved in bacteria
E3S87_RS08465	COG0668	transmembrane transport
E3S87_RS08470	COG1475	DNA binding
E3S87_RS08475	COG0626	cystathionine gamma-synthase activity
E3S87_RS08480	COG0626	cystathionine gamma-synthase activity
E3S87_RS08485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3S87_RS08485	COG0646	methionine synthase
E3S87_RS08515	COG1131	(ABC) transporter
E3S87_RS08525	COG1476	TRANSCRIPTIONal
E3S87_RS08535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3S87_RS08540	COG0805	protein transport
E3S87_RS08545	COG0672	)-iron permease
E3S87_RS08550	COG2837	iron assimilation
E3S87_RS08555	COG2822	iron ion transport
E3S87_RS08560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S87_RS08575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S87_RS08580	COG0346	lactoylglutathione lyase activity
E3S87_RS08585	COG2271	Major facilitator Superfamily
E3S87_RS08610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S87_RS08620	COG3037	sugar-specific permease SgaT UlaA
E3S87_RS08650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S87_RS08700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3S87_RS08705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S87_RS08735	COG0577	efflux transmembrane transporter activity
E3S87_RS08740	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E3S87_RS08745	COG1114	Component of the transport system for branched-chain amino acids
E3S87_RS08855	COG1388	LysM domain
E3S87_RS08855	COG3942	CHAP domain
E3S87_RS08930	COG2226	methyltransferase
E3S87_RS08935	COG2723	6-phospho-beta-galactosidase activity
E3S87_RS08940	COG1263	PTS System
E3S87_RS08940	COG2190	(PTS) system
E3S87_RS08940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S87_RS08945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S87_RS08985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S87_RS08990	COG1063	alcohol dehydrogenase
E3S87_RS09000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S87_RS09005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S87_RS09010	COG1063	alcohol dehydrogenase
E3S87_RS09020	COG1063	alcohol dehydrogenase
E3S87_RS09030	COG1063	alcohol dehydrogenase
E3S87_RS09035	COG3775	system Galactitol-specific IIC component
E3S87_RS09040	COG3414	Phosphotransferase system galactitol-specific IIB component
E3S87_RS09060	COG1957	nucleoside hydrolase
E3S87_RS09065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S87_RS09065	COG2190	(PTS) system
E3S87_RS09065	COG1263	PTS System
E3S87_RS09090	COG3189	MarR family transcriptional regulator
E3S87_RS09095	COG0747	negative chemotaxis
E3S87_RS09115	COG0318	PFAM AMP-dependent synthetase and ligase
E3S87_RS09120	COG1960	acyl-CoA dehydrogenase activity
E3S87_RS09130	COG0183	Belongs to the thiolase family
E3S87_RS09185	COG1755	Isoprenylcysteine carboxyl methyltransferase
E3S87_RS09195	COG0673	inositol 2-dehydrogenase activity
E3S87_RS09200	COG0673	inositol 2-dehydrogenase activity
E3S87_RS09205	COG3833	ABC-type maltose transport systems, permease component
E3S87_RS09210	COG1175	transmembrane transport
E3S87_RS09220	COG3842	ATPase activity
E3S87_RS09235	COG0405	Gamma-glutamyltransferase
E3S87_RS09245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S87_RS09305	COG3961	Belongs to the TPP enzyme family
E3S87_RS09310	COG1335	isochorismatase
E3S87_RS09315	COG1114	Component of the transport system for branched-chain amino acids
E3S87_RS09365	COG5609	conserved protein (DUF2294)
E3S87_RS09370	COG1960	acyl-CoA dehydrogenase activity
E3S87_RS09375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3S87_RS09410	COG2832	Protein of unknown function (DUF454)
E3S87_RS09420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S87_RS09425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3S87_RS09435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S87_RS09465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S87_RS09475	COG1086	Polysaccharide biosynthesis protein
E3S87_RS09500	COG1454	alcohol dehydrogenase
E3S87_RS09500	COG1012	belongs to the aldehyde dehydrogenase family
E3S87_RS09515	COG0737	Belongs to the 5'-nucleotidase family
E3S87_RS09535	COG3639	organic phosphonate transmembrane transporter activity
E3S87_RS09555	COG2814	Major facilitator Superfamily
E3S87_RS09560	COG0813	purine-nucleoside phosphorylase activity
E3S87_RS09590	COG0438	transferase activity, transferring glycosyl groups
E3S87_RS09595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S87_RS09600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3S87_RS09620	COG1475	DNA binding
E3S87_RS09625	COG0019	diaminopimelate decarboxylase activity
E3S87_RS09635	COG4264	IucA IucC family
E3S87_RS09640	COG4264	IucA IucC family
E3S87_RS09645	COG2814	Major facilitator Superfamily
E3S87_RS09650	COG4264	IucA IucC family
E3S87_RS09655	COG2423	ornithine cyclodeaminase activity
E3S87_RS09665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S87_RS09670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S87_RS09675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S87_RS09690	COG1620	l-lactate permease
E3S87_RS09700	COG4716	Myosin-crossreactive antigen
E3S87_RS09705	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3S87_RS09715	COG1473	amidohydrolase
E3S87_RS09730	COG0823	Involved in the tonB-independent uptake of proteins
E3S87_RS09765	COG0456	acetyltransferase
E3S87_RS09785	COG2814	Major facilitator Superfamily
E3S87_RS09805	COG4268	DNA restriction-modification system
E3S87_RS09810	COG1401	restriction endodeoxyribonuclease activity
E3S87_RS09820	COG2826	transposase and inactivated derivatives, IS30 family
E3S87_RS09845	COG0737	Belongs to the 5'-nucleotidase family
E3S87_RS09850	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3S87_RS09860	COG4863	YycH protein
E3S87_RS09890	COG0305	Participates in initiation and elongation during chromosome replication
E3S87_RS09900	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E3S87_RS09910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3S87_RS09935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3S87_RS09955	COG2501	S4 domain
E3S87_RS09995	COG1475	DNA binding
E3S87_RS10015	COG1278	Cold shock
E3S87_RS10045	COG0577	efflux transmembrane transporter activity
E3S87_RS10050	COG1136	(ABC) transporter
E3S87_RS10065	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3S87_RS10075	COG2962	Rard protein
E3S87_RS10080	COG0471	metal ion transport
E3S87_RS10160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3S87_RS10210	COG1215	transferase activity, transferring glycosyl groups
E3S87_RS10215	COG1309	transcriptional regulator
E3S87_RS10245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S87_RS10270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S87_RS10280	COG0201	protein transport
E3S87_RS10295	COG1073	alpha beta
E3S87_RS10310	COG0438	transferase activity, transferring glycosyl groups
E3S87_RS10325	COG3433	isochorismatase activity
E3S87_RS10325	COG1535	isochorismatase
E3S87_RS10330	COG3942	CHAP domain
E3S87_RS10330	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3S87_RS10340	COG1482	cell wall glycoprotein biosynthetic process
E3S87_RS10345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S87_RS10345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S87_RS10345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S87_RS10350	COG3711	transcriptional antiterminator
E3S87_RS10350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S87_RS10370	COG1438	arginine binding
E3S87_RS10415	COG1846	Transcriptional regulator
E3S87_RS10425	COG1785	Belongs to the alkaline phosphatase family
E3S87_RS10435	COG0745	RESPONSE REGULATOR receiver
E3S87_RS10440	COG2205	protein histidine kinase activity
E3S87_RS10445	COG1136	(ABC) transporter
E3S87_RS10465	COG0386	Belongs to the glutathione peroxidase family
E3S87_RS10475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3S87_RS10490	COG2851	Citrate transporter
E3S87_RS10515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S87_RS10520	COG1510	regulation of RNA biosynthetic process
E3S87_RS10550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S87_RS10580	COG0531	amino acid
E3S87_RS10590	COG3527	Alpha-acetolactate decarboxylase
E3S87_RS10645	COG0167	dihydroorotate dehydrogenase activity
E3S87_RS10785	COG0436	Aminotransferase
E3S87_RS10830	COG2409	Drug exporters of the RND superfamily
E3S87_RS10855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3S87_RS10860	COG3425	synthase
E3S87_RS10870	COG3942	CHAP domain
E3S87_RS10880	COG0583	DNA-binding transcription factor activity
E3S87_RS10895	COG0028	Belongs to the TPP enzyme family
E3S87_RS10915	COG0657	acetylesterase activity
E3S87_RS10920	COG0697	spore germination
E3S87_RS10935	COG1760	l-serine dehydratase
E3S87_RS10940	COG1760	l-serine dehydratase
E3S87_RS10960	COG3764	Sortase (surface protein transpeptidase)
E3S87_RS10965	COG0561	phosphatase activity
E3S87_RS10985	COG2514	catechol 2,3-dioxygenase activity
E3S87_RS10995	COG1846	Transcriptional regulator
E3S87_RS11000	COG0346	lactoylglutathione lyase activity
E3S87_RS11005	COG0400	carboxylic ester hydrolase activity
E3S87_RS11025	COG1131	(ABC) transporter
E3S87_RS11030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S87_RS11040	COG1279	arginine transmembrane transporter activity
E3S87_RS11045	COG0586	Pfam SNARE associated Golgi protein
E3S87_RS11050	COG2271	Major facilitator Superfamily
E3S87_RS11060	COG4876	unkown
E3S87_RS11065	COG2357	RelA SpoT domain protein
E3S87_RS11070	COG0789	Transcriptional regulator
E3S87_RS11075	COG1802	Transcriptional regulator
E3S87_RS11080	COG1070	Carbohydrate kinase
E3S87_RS11125	COG0494	nUDIX hydrolase
E3S87_RS11200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3S87_RS11205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3S87_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
E3S87_RS11215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3S87_RS11235	COG0747	negative chemotaxis
E3S87_RS11240	COG0601	transmembrane transport
E3S87_RS11245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S87_RS11255	COG1124	(ABC) transporter
E3S87_RS11270	COG0069	glutamate synthase activity
E3S87_RS11275	COG4808	Protein conserved in bacteria
E3S87_RS11280	COG1363	Peptidase, m42
E3S87_RS11285	COG4619	ABC transporter
E3S87_RS11290	COG0390	transport system, permease component
E3S87_RS11295	COG2814	Major facilitator Superfamily
E3S87_RS11300	COG2272	Belongs to the type-B carboxylesterase lipase family
E3S87_RS11305	COG0531	amino acid
E3S87_RS11310	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E3S87_RS11330	COG1174	glycine betaine transport
E3S87_RS11340	COG1174	glycine betaine transport
E3S87_RS11350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S87_RS11365	COG0531	amino acid
E3S87_RS11375	COG1113	amino acid transport
E3S87_RS11395	COG2814	Major facilitator Superfamily
E3S87_RS11405	COG1929	Belongs to the glycerate kinase type-1 family
E3S87_RS11425	COG1132	(ABC) transporter
E3S87_RS11435	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3S87_RS11440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3S87_RS11450	COG0156	8-amino-7-oxononanoate synthase activity
E3S87_RS11490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E3S87_RS11505	COG2814	Major facilitator Superfamily
E3S87_RS11510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3S87_RS11515	COG0765	amino acid transport
E3S87_RS11520	COG1126	abc transporter atp-binding protein
E3S87_RS11555	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3S87_RS11555	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S87_RS11570	COG2116	formate transmembrane transporter activity
E3S87_RS11575	COG0454	-acetyltransferase
E3S87_RS11585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3S87_RS11590	COG2146	nitrite reductase [NAD(P)H] activity
E3S87_RS11600	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3S87_RS11605	COG1140	nitrate reductase beta subunit
E3S87_RS11615	COG2181	nitrate reductase activity
E3S87_RS11680	COG3871	stress protein (general stress protein 26)
E3S87_RS11695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S87_RS11695	COG1263	PTS System
E3S87_RS11710	COG1511	domain protein
E3S87_RS11735	COG0604	alcohol dehydrogenase
E3S87_RS11755	COG1620	l-lactate permease
E3S87_RS11770	COG1131	(ABC) transporter
E3S87_RS11845	COG1566	PFAM secretion protein HlyD family protein
E3S87_RS11850	COG2814	Major facilitator Superfamily
E3S87_RS11860	COG0657	acetylesterase activity
E3S87_RS11875	COG0598	Magnesium transport protein CorA
E3S87_RS11885	COG0786	glutamate:sodium symporter activity
E3S87_RS11900	COG4152	abc transporter atp-binding protein
E3S87_RS11905	COG1668	transmembrane transport
E3S87_RS11925	COG2258	MOSC domain
E3S87_RS11950	COG0583	DNA-binding transcription factor activity
E3S87_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
E3S87_RS11990	COG1737	Transcriptional regulator
E3S87_RS11995	COG1263	PTS System
E3S87_RS11995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S87_RS12010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3S87_RS12030	COG1113	amino acid transport
E3S87_RS12110	COG1757	Na H antiporter
E3S87_RS12180	COG4413	Urea transporter
E3S87_RS12185	COG1960	acyl-CoA dehydrogenase activity
E3S87_RS12200	COG1268	BioY protein
E3S87_RS12215	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3S87_RS12220	COG4149	molybdate abc transporter
E3S87_RS12225	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3S87_RS12230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3S87_RS12250	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3S87_RS12310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3S87_RS12355	COG2252	PERMEase
E3S87_RS12470	COG0201	protein transport
E3S87_RS12565	COG0028	Belongs to the TPP enzyme family
E3S87_RS12570	COG3527	Alpha-acetolactate decarboxylase
E3S87_RS12590	COG5492	domain, Protein
E3S87_RS12600	COG0789	Transcriptional regulator
E3S87_RS12605	COG0656	L-ascorbic acid biosynthetic process
E3S87_RS12680	COG2130	NADP-dependent
E3S87_RS12690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S87_RS12715	COG2814	Major facilitator Superfamily
E3S87_RS12720	COG4264	IucA IucC family
E3S87_RS12725	COG3457	Alanine racemase
E3S87_RS12735	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S87_RS12740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S87_RS12745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S87_RS12760	COG1988	membrane-bound metal-dependent
E3S87_RS12770	COG1272	protein, Hemolysin III
E3S87_RS12790	COG0489	protein tyrosine kinase activity
E3S87_RS12850	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E3S87_RS12880	COG3711	transcriptional antiterminator
E3S87_RS12895	COG1119	ATPase activity
E3S87_RS12900	COG0561	phosphatase activity
E3S87_RS12930	COG0640	Transcriptional regulator
E3S87_RS12935	COG0702	epimerase
E3S87_RS12940	COG1482	cell wall glycoprotein biosynthetic process
E3S87_RS12960	COG0783	Belongs to the Dps family
E3S87_RS12965	COG0813	purine-nucleoside phosphorylase activity
E3S87_RS13010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S87_RS13050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3S87_RS13070	COG2890	protein-(glutamine-N5) methyltransferase activity
E3S87_RS13075	COG0009	L-threonylcarbamoyladenylate synthase
E3S87_RS13100	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S87_RS13175	COG0629	single-stranded DNA binding
E3S87_RS13215	COG1418	mRNA catabolic process
E3S87_RS13225	COG1937	Protein conserved in bacteria
E3S87_RS13245	COG0772	Belongs to the SEDS family
E3S87_RS13255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3S87_RS13265	COG0745	RESPONSE REGULATOR receiver
E3S87_RS13270	COG2205	protein histidine kinase activity
E3S87_RS13300	COG3428	Bacterial PH domain
E3S87_RS13330	COG2208	phosphoserine phosphatase activity
E3S87_RS13335	COG1366	Belongs to the anti-sigma-factor antagonist family
E3S87_RS13345	COG1191	sigma factor activity
E3S87_RS13350	COG2183	response to ionizing radiation
E3S87_RS13425	COG0028	Belongs to the TPP enzyme family
E3S87_RS13440	COG0802	atpase or kinase
E3S87_RS13445	COG1214	PFAM Peptidase M22, glycoprotease
E3S87_RS13450	COG0456	acetyltransferase
E3S87_RS13460	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E3S87_RS13470	COG0488	(ABC) transporter
E3S87_RS13480	COG2391	methyltransferase activity
E3S87_RS13485	COG0425	Belongs to the sulfur carrier protein TusA family
E3S87_RS13490	COG0004	ammonium transporteR
E3S87_RS13495	COG1609	Transcriptional regulator
E3S87_RS13500	COG1621	beta-fructofuranosidase activity
E3S87_RS13505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3S87_RS13565	COG0582	viral genome integration into host DNA
E3S87_RS13650	COG3728	DNA packaging
E3S87_RS13650	COG5484	DNA packaging
E3S87_RS13685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S87_RS13735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair