locus-tag	class	description
ACO02_RS00005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACO02_RS00025	COG4846	Membrane protein involved in cytochrome C biogenesis
ACO02_RS00060	COG2340	Cysteine-rich secretory protein family
ACO02_RS00090	COG0833	amino acid
ACO02_RS00115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACO02_RS00120	COG0460	homoserine dehydrogenase
ACO02_RS00125	COG0527	aspartate kinase activity
ACO02_RS00140	COG1525	nuclease
ACO02_RS00150	COG2197	response regulator
ACO02_RS00165	COG1131	(ABC) transporter
ACO02_RS00285	COG0789	Transcriptional regulator
ACO02_RS00290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ACO02_RS00295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACO02_RS00305	COG1923	regulation of RNA biosynthetic process
ACO02_RS00330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACO02_RS00335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ACO02_RS00370	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACO02_RS00375	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACO02_RS00375	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACO02_RS00380	COG1692	metallophosphoesterase
ACO02_RS00400	COG1058	Belongs to the CinA family
ACO02_RS00400	COG1546	Belongs to the CinA family
ACO02_RS00420	COG0300	oxidoreductase activity
ACO02_RS00425	COG0612	Peptidase, M16
ACO02_RS00430	COG0612	Peptidase, M16
ACO02_RS00435	COG2188	Transcriptional regulator
ACO02_RS00465	COG0196	riboflavin kinase activity
ACO02_RS00490	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ACO02_RS00495	COG0195	Participates in both transcription termination and antitermination
ACO02_RS00595	COG0758	DNA mediated transformation
ACO02_RS00655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACO02_RS00665	COG0552	protein localization to endoplasmic reticulum
ACO02_RS00670	COG1196	nuclear chromosome segregation
ACO02_RS00710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACO02_RS00720	COG1302	Protein conserved in bacteria
ACO02_RS00735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACO02_RS00750	COG0631	protein serine/threonine phosphatase activity
ACO02_RS00760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACO02_RS00760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACO02_RS00775	COG2314	TM2 domain
ACO02_RS00785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACO02_RS00790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACO02_RS00805	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ACO02_RS00850	COG2233	PERMEase
ACO02_RS00860	COG0564	pseudouridine synthase activity
ACO02_RS00880	COG2514	catechol 2,3-dioxygenase activity
ACO02_RS00890	COG3599	regulation of cell shape
ACO02_RS00895	COG2302	S4 RNA-binding domain
ACO02_RS00900	COG0762	integral membrane protein
ACO02_RS00910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACO02_RS00925	COG0849	cell division
ACO02_RS00930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACO02_RS00945	COG0768	penicillin binding
ACO02_RS00950	COG4839	cell division protein FtsL
ACO02_RS00975	COG1011	Hydrolase
ACO02_RS01010	COG1288	antiporter activity
ACO02_RS01125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACO02_RS01130	COG1053	succinate dehydrogenase
ACO02_RS01135	COG2009	succinate dehydrogenase
ACO02_RS01160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACO02_RS01160	COG1796	DNA polymerase
ACO02_RS01195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACO02_RS01210	COG4509	Sortase family
ACO02_RS01270	COG0742	ribosomal rna small subunit methyltransferase
ACO02_RS01290	COG3679	Belongs to the UPF0342 family
ACO02_RS01325	COG0772	Belongs to the SEDS family
ACO02_RS01335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACO02_RS01345	COG1217	gtp-binding protein TYPA
ACO02_RS01355	COG0483	inositol monophosphate 1-phosphatase activity
ACO02_RS01380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACO02_RS01385	COG1177	transmembrane transport
ACO02_RS01390	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACO02_RS01455	COG0569	domain protein
ACO02_RS01460	COG1294	oxidase, subunit
ACO02_RS01465	COG1271	oxidase subunit
ACO02_RS01490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACO02_RS01515	COG4721	ABC-type cobalt transport system, permease component
ACO02_RS01520	COG4172	Belongs to the ABC transporter superfamily
ACO02_RS01525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACO02_RS01565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACO02_RS01580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACO02_RS01625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACO02_RS01630	COG1316	TRANSCRIPTIONal
ACO02_RS01660	COG3594	Acyltransferase
ACO02_RS01665	COG0436	Aminotransferase
ACO02_RS01690	COG2267	carboxylic ester hydrolase activity
ACO02_RS01700	COG1169	isochorismate synthase
ACO02_RS01710	COG1575	Belongs to the MenA family. Type 1 subfamily
ACO02_RS01715	COG0456	acetyltransferase
ACO02_RS01720	COG2314	TM2 domain
ACO02_RS01730	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ACO02_RS01790	COG4873	Protein conserved in bacteria
ACO02_RS01805	COG4903	ComK protein
ACO02_RS01820	COG0737	Belongs to the 5'-nucleotidase family
ACO02_RS01825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACO02_RS01835	COG0861	Integral membrane protein TerC family
ACO02_RS01875	COG1115	amino acid carrier protein
ACO02_RS01880	COG0628	permease
ACO02_RS01890	COG0569	domain protein
ACO02_RS01890	COG0475	glutathione-regulated potassium exporter activity
ACO02_RS01895	COG2239	Acts as a magnesium transporter
ACO02_RS01900	COG0564	pseudouridine synthase activity
ACO02_RS01910	COG2357	RelA SpoT domain protein
ACO02_RS01925	COG2346	COG2346, Truncated hemoglobins
ACO02_RS01935	COG1164	Oligoendopeptidase f
ACO02_RS01965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACO02_RS01970	COG0601	transmembrane transport
ACO02_RS01975	COG4608	Belongs to the ABC transporter superfamily
ACO02_RS01980	COG0444	Belongs to the ABC transporter superfamily
ACO02_RS01985	COG0747	negative chemotaxis
ACO02_RS01990	COG4166	transmembrane transport
ACO02_RS01995	COG4608	Belongs to the ABC transporter superfamily
ACO02_RS02000	COG0444	Belongs to the ABC transporter superfamily
ACO02_RS02005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACO02_RS02010	COG0601	transmembrane transport
ACO02_RS02040	COG1881	PFAM PEBP family protein
ACO02_RS02055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACO02_RS02080	COG0561	phosphatase activity
ACO02_RS02120	COG0398	Pfam SNARE associated Golgi protein
ACO02_RS02140	COG0584	glycerophosphoryl diester phosphodiesterase
ACO02_RS02160	COG1902	pentaerythritol trinitrate reductase activity
ACO02_RS02165	COG1098	S1 RNA binding domain
ACO02_RS02220	COG2050	protein possibly involved in aromatic compounds catabolism
ACO02_RS02225	COG2056	Na+-H+ antiporter family
ACO02_RS02230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACO02_RS02240	COG0316	Belongs to the HesB IscA family
ACO02_RS02250	COG1252	NADH dehydrogenase
ACO02_RS02255	COG4837	Protein of unknown function (DUF1462)
ACO02_RS02260	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACO02_RS02265	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ACO02_RS02275	COG1696	Membrane protein involved in D-alanine export
ACO02_RS02305	COG2445	Protein of unknown function DUF86
ACO02_RS02315	COG4470	Protein conserved in bacteria
ACO02_RS02330	COG0730	response to heat
ACO02_RS02335	COG1801	Protein of unknown function DUF72
ACO02_RS02350	COG1253	flavin adenine dinucleotide binding
ACO02_RS02375	COG0822	iron-sulfur transferase activity
ACO02_RS02385	COG0719	Fe-S assembly protein
ACO02_RS02390	COG0396	ATPase activity
ACO02_RS02405	COG1464	Belongs to the NlpA lipoprotein family
ACO02_RS02410	COG2011	ABC-type metal ion transport system permease component
ACO02_RS02425	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ACO02_RS02435	COG3878	Protein conserved in bacteria
ACO02_RS02450	COG1393	Belongs to the ArsC family
ACO02_RS02455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACO02_RS02480	COG1279	arginine transmembrane transporter activity
ACO02_RS02485	COG0406	alpha-ribazole phosphatase activity
ACO02_RS02525	COG1278	Cold shock
ACO02_RS02600	COG0557	exoribonuclease II activity
ACO02_RS02605	COG1647	Serine aminopeptidase, S33
ACO02_RS02610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACO02_RS02675	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACO02_RS02735	COG1388	LysM domain
ACO02_RS02735	COG3942	CHAP domain
ACO02_RS02765	COG1040	competence protein
ACO02_RS02770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ACO02_RS02780	COG1739	Uncharacterized protein family UPF0029
ACO02_RS02785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACO02_RS02840	COG4607	ABC-type enterochelin transport system periplasmic component
ACO02_RS02845	COG4604	ABC transporter, ATP-binding protein
ACO02_RS02850	COG4605	iron ion homeostasis
ACO02_RS02855	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACO02_RS02875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACO02_RS02880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACO02_RS02910	COG3104	oligopeptide transport
ACO02_RS02940	COG1174	glycine betaine transport
ACO02_RS02945	COG1125	glycine betaine transport
ACO02_RS02945	COG0517	IMP dehydrogenase activity
ACO02_RS02950	COG0514	ATP-dependent DNA helicase (RecQ)
ACO02_RS02955	COG0488	(ABC) transporter
ACO02_RS02985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACO02_RS02990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACO02_RS02990	COG0512	Glutamine amidotransferase of anthranilate synthase
ACO02_RS03000	COG0720	synthase
ACO02_RS03035	COG0463	Glycosyl transferase, family 2
ACO02_RS03040	COG0656	L-ascorbic acid biosynthetic process
ACO02_RS03045	COG1253	flavin adenine dinucleotide binding
ACO02_RS03050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACO02_RS03055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACO02_RS03055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACO02_RS03055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACO02_RS03060	COG1105	Belongs to the carbohydrate kinase PfkB family
ACO02_RS03065	COG1349	DNA-binding transcription factor activity
ACO02_RS03070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACO02_RS03100	COG0415	Belongs to the DNA photolyase family
ACO02_RS03105	COG0471	metal ion transport
ACO02_RS03115	COG4989	oxidoreductase activity
ACO02_RS03120	COG0523	cobalamin synthesis protein
ACO02_RS03130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACO02_RS03135	COG4988	ABC transporter
ACO02_RS03155	COG1611	Belongs to the LOG family
ACO02_RS03185	COG2839	Protein conserved in bacteria
ACO02_RS03190	COG2814	Major facilitator Superfamily
ACO02_RS03200	COG0583	DNA-binding transcription factor activity
ACO02_RS03240	COG1388	LysM domain
ACO02_RS03240	COG3942	CHAP domain
ACO02_RS03245	COG0306	phosphate transporter
ACO02_RS03250	COG1392	Phosphate transport regulator
ACO02_RS03255	COG0577	efflux transmembrane transporter activity
ACO02_RS03260	COG1136	(ABC) transporter
ACO02_RS03275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACO02_RS03300	COG3949	Membrane
ACO02_RS03310	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ACO02_RS03320	COG2376	Dihydroxyacetone kinase
ACO02_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACO02_RS03330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACO02_RS03335	COG1120	ATPase activity
ACO02_RS03340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACO02_RS03350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACO02_RS03355	COG1132	(ABC) transporter
ACO02_RS03360	COG1686	Belongs to the peptidase S11 family
ACO02_RS03365	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACO02_RS03370	COG1216	Glycosyl transferase, family 2
ACO02_RS03375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ACO02_RS03380	COG1682	transport, permease protein
ACO02_RS03390	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ACO02_RS03400	COG1321	iron dependent repressor
ACO02_RS03405	COG1121	(ABC) transporter
ACO02_RS03410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACO02_RS03460	COG4974	Belongs to the 'phage' integrase family
ACO02_RS03495	COG2946	Replication initiation factor
ACO02_RS03515	COG0433	COG0433 Predicted ATPase
ACO02_RS03520	COG1674	ftsk spoiiie
ACO02_RS03550	COG2826	transposase and inactivated derivatives, IS30 family
ACO02_RS03590	COG4139	cobalamin transport
ACO02_RS03595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACO02_RS03635	COG1078	dGTPase activity
ACO02_RS03645	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACO02_RS03650	COG0667	Aldo Keto reductase
ACO02_RS03760	COG0083	homoserine kinase activity
ACO02_RS03765	COG0095	Lipoate-protein ligase
ACO02_RS03880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACO02_RS03925	COG0561	phosphatase activity
ACO02_RS03935	COG1428	Deoxynucleoside kinase
ACO02_RS03940	COG1428	Deoxynucleoside kinase
ACO02_RS03945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACO02_RS03980	COG1473	amidohydrolase
ACO02_RS04020	COG2813	Specifically methylates the guanine in position
ACO02_RS04080	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ACO02_RS04105	COG4956	integral membrane protein (PIN domain superfamily)
ACO02_RS04110	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACO02_RS04125	COG3880	PFAM UvrB UvrC protein
ACO02_RS04135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACO02_RS04150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACO02_RS04245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACO02_RS04270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACO02_RS04285	COG1098	S1 RNA binding domain
ACO02_RS04295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACO02_RS04300	COG3956	TIGRFAM MazG family protein
ACO02_RS04305	COG2244	polysaccharide biosynthetic process
ACO02_RS04350	COG0251	oxidation-reduction process
ACO02_RS04355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACO02_RS04365	COG4466	Protein conserved in bacteria
ACO02_RS04375	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ACO02_RS04380	COG0084	hydrolase, TatD family'
ACO02_RS04390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACO02_RS04400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACO02_RS04410	COG1774	PSP1 C-terminal conserved region
ACO02_RS04415	COG0470	DNA polymerase III
ACO02_RS04420	COG3870	Protein conserved in bacteria
ACO02_RS04430	COG1982	Orn Lys Arg decarboxylase major
ACO02_RS04470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACO02_RS04490	COG2188	Transcriptional regulator
ACO02_RS04495	COG0366	Alpha amylase catalytic
ACO02_RS04500	COG1263	PTS System
ACO02_RS04500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACO02_RS04510	COG0493	'glutamate synthase
ACO02_RS04515	COG0070	glutamate synthase
ACO02_RS04515	COG0069	glutamate synthase activity
ACO02_RS04515	COG0067	glutamate synthase
ACO02_RS04520	COG0583	DNA-binding transcription factor activity
ACO02_RS04555	COG1464	Belongs to the NlpA lipoprotein family
ACO02_RS04560	COG2011	ABC-type metal ion transport system permease component
ACO02_RS04570	COG0626	cystathionine gamma-synthase activity
ACO02_RS04575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACO02_RS04580	COG0733	neurotransmitter:sodium symporter activity
ACO02_RS04590	COG1647	Serine aminopeptidase, S33
ACO02_RS04605	COG5609	conserved protein (DUF2294)
ACO02_RS04615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACO02_RS04640	COG0523	cobalamin synthesis protein
ACO02_RS04805	COG3759	membrane
ACO02_RS04845	COG2233	PERMEase
ACO02_RS04880	COG1823	symporter activity
ACO02_RS04895	COG3634	alkyl hydroperoxide reductase activity
ACO02_RS04990	COG0012	GTP binding
ACO02_RS04995	COG4481	Protein conserved in bacteria
ACO02_RS05000	COG0668	transmembrane transport
ACO02_RS05005	COG1475	DNA binding
ACO02_RS05015	COG0626	cystathionine gamma-synthase activity
ACO02_RS05020	COG0626	cystathionine gamma-synthase activity
ACO02_RS05025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACO02_RS05025	COG0646	methionine synthase
ACO02_RS05055	COG1131	(ABC) transporter
ACO02_RS05065	COG1476	TRANSCRIPTIONal
ACO02_RS05075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACO02_RS05080	COG0805	protein transport
ACO02_RS05085	COG0672	)-iron permease
ACO02_RS05100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACO02_RS05115	COG0431	NADPH-dependent FMN reductase
ACO02_RS05120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACO02_RS05125	COG0346	lactoylglutathione lyase activity
ACO02_RS05130	COG2271	Major facilitator Superfamily
ACO02_RS05155	COG3711	transcriptional antiterminator
ACO02_RS05160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACO02_RS05170	COG3037	sugar-specific permease SgaT UlaA
ACO02_RS05200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACO02_RS05225	COG3314	Sporulation integral membrane protein YlbJ
ACO02_RS05250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACO02_RS05255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACO02_RS05285	COG0577	efflux transmembrane transporter activity
ACO02_RS05295	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ACO02_RS05305	COG1114	Component of the transport system for branched-chain amino acids
ACO02_RS05455	COG3942	CHAP domain
ACO02_RS05455	COG1388	LysM domain
ACO02_RS05485	COG1131	(ABC) transporter
ACO02_RS05545	COG2226	methyltransferase
ACO02_RS05555	COG2723	6-phospho-beta-galactosidase activity
ACO02_RS05560	COG1263	PTS System
ACO02_RS05560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACO02_RS05560	COG2190	(PTS) system
ACO02_RS05570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACO02_RS05605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ACO02_RS05610	COG1063	alcohol dehydrogenase
ACO02_RS05620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ACO02_RS05625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ACO02_RS05630	COG1063	alcohol dehydrogenase
ACO02_RS05640	COG1063	alcohol dehydrogenase
ACO02_RS05650	COG1063	alcohol dehydrogenase
ACO02_RS05655	COG3775	system Galactitol-specific IIC component
ACO02_RS05660	COG3414	Phosphotransferase system galactitol-specific IIB component
ACO02_RS05680	COG1957	nucleoside hydrolase
ACO02_RS05685	COG2190	(PTS) system
ACO02_RS05685	COG1263	PTS System
ACO02_RS05685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACO02_RS05720	COG3189	MarR family transcriptional regulator
ACO02_RS05725	COG0747	negative chemotaxis
ACO02_RS05740	COG0318	PFAM AMP-dependent synthetase and ligase
ACO02_RS05745	COG1960	acyl-CoA dehydrogenase activity
ACO02_RS05755	COG0183	Belongs to the thiolase family
ACO02_RS05815	COG1755	Isoprenylcysteine carboxyl methyltransferase
ACO02_RS05825	COG0673	inositol 2-dehydrogenase activity
ACO02_RS05830	COG0673	inositol 2-dehydrogenase activity
ACO02_RS05835	COG3833	ABC-type maltose transport systems, permease component
ACO02_RS05840	COG1175	transmembrane transport
ACO02_RS05850	COG3842	ATPase activity
ACO02_RS05870	COG0405	Gamma-glutamyltransferase
ACO02_RS05880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACO02_RS05885	COG0601	transmembrane transport
ACO02_RS05920	COG1737	Transcriptional regulator
ACO02_RS05950	COG3961	Belongs to the TPP enzyme family
ACO02_RS05955	COG1335	isochorismatase
ACO02_RS05960	COG1114	Component of the transport system for branched-chain amino acids
ACO02_RS06010	COG5609	conserved protein (DUF2294)
ACO02_RS06015	COG1960	acyl-CoA dehydrogenase activity
ACO02_RS06020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACO02_RS06055	COG2832	Protein of unknown function (DUF454)
ACO02_RS06065	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACO02_RS06070	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACO02_RS06080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACO02_RS06110	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACO02_RS06120	COG1086	Polysaccharide biosynthesis protein
ACO02_RS06145	COG1454	alcohol dehydrogenase
ACO02_RS06145	COG1012	belongs to the aldehyde dehydrogenase family
ACO02_RS06175	COG0737	Belongs to the 5'-nucleotidase family
ACO02_RS06195	COG3639	organic phosphonate transmembrane transporter activity
ACO02_RS06215	COG2814	Major facilitator Superfamily
ACO02_RS06220	COG0813	purine-nucleoside phosphorylase activity
ACO02_RS06255	COG0438	transferase activity, transferring glycosyl groups
ACO02_RS06260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACO02_RS06265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACO02_RS06295	COG1475	DNA binding
ACO02_RS06300	COG0019	diaminopimelate decarboxylase activity
ACO02_RS06310	COG4264	IucA IucC family
ACO02_RS06315	COG4264	IucA IucC family
ACO02_RS06320	COG2814	Major facilitator Superfamily
ACO02_RS06325	COG4264	IucA IucC family
ACO02_RS06330	COG2423	ornithine cyclodeaminase activity
ACO02_RS06340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACO02_RS06345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACO02_RS06350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACO02_RS06370	COG1620	l-lactate permease
ACO02_RS06385	COG0697	spore germination
ACO02_RS06390	COG4716	Myosin-crossreactive antigen
ACO02_RS06395	COG1283	sodium-dependent phosphate transmembrane transporter activity
ACO02_RS06405	COG1473	amidohydrolase
ACO02_RS06435	COG0823	Involved in the tonB-independent uptake of proteins
ACO02_RS06455	COG0583	DNA-binding transcription factor activity
ACO02_RS06515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACO02_RS06520	COG2210	Belongs to the sulfur carrier protein TusA family
ACO02_RS06525	COG1937	Protein conserved in bacteria
ACO02_RS06530	COG0730	response to heat
ACO02_RS06560	COG1388	LysM domain
ACO02_RS06570	COG1124	(ABC) transporter
ACO02_RS06575	COG4172	Belongs to the ABC transporter superfamily
ACO02_RS06580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACO02_RS06630	COG2235	arginine
ACO02_RS06640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACO02_RS06645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACO02_RS06695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACO02_RS06820	COG2030	dehydratase
ACO02_RS06825	COG0584	glycerophosphoryl diester phosphodiesterase
ACO02_RS06855	COG0737	Belongs to the 5'-nucleotidase family
ACO02_RS06860	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACO02_RS06870	COG4863	YycH protein
ACO02_RS06905	COG0305	Participates in initiation and elongation during chromosome replication
ACO02_RS06915	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ACO02_RS06925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACO02_RS06955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACO02_RS06975	COG2501	S4 domain
ACO02_RS07015	COG1475	DNA binding
ACO02_RS07040	COG1278	Cold shock
ACO02_RS07070	COG0577	efflux transmembrane transporter activity
ACO02_RS07075	COG1136	(ABC) transporter
ACO02_RS07090	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ACO02_RS07100	COG2962	Rard protein
ACO02_RS07105	COG0471	metal ion transport
ACO02_RS07190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACO02_RS07225	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ACO02_RS07280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACO02_RS07300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACO02_RS07320	COG1073	alpha beta
ACO02_RS07335	COG0438	transferase activity, transferring glycosyl groups
ACO02_RS07350	COG1535	isochorismatase
ACO02_RS07350	COG3433	isochorismatase activity
ACO02_RS07355	COG1705	Flagellar rod assembly protein muramidase FlgJ
ACO02_RS07355	COG3942	CHAP domain
ACO02_RS07365	COG1482	cell wall glycoprotein biosynthetic process
ACO02_RS07370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACO02_RS07370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACO02_RS07370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACO02_RS07375	COG3711	transcriptional antiterminator
ACO02_RS07375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACO02_RS07395	COG1438	arginine binding
ACO02_RS07440	COG1846	Transcriptional regulator
ACO02_RS07450	COG1785	Belongs to the alkaline phosphatase family
ACO02_RS07460	COG0745	RESPONSE REGULATOR receiver
ACO02_RS07465	COG2205	protein histidine kinase activity
ACO02_RS07470	COG1136	(ABC) transporter
ACO02_RS07495	COG0386	Belongs to the glutathione peroxidase family
ACO02_RS07505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACO02_RS07520	COG2851	Citrate transporter
ACO02_RS07545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACO02_RS07555	COG1510	regulation of RNA biosynthetic process
ACO02_RS07565	COG1012	belongs to the aldehyde dehydrogenase family
ACO02_RS07585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACO02_RS07615	COG0531	amino acid
ACO02_RS07630	COG3527	Alpha-acetolactate decarboxylase
ACO02_RS07635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACO02_RS07685	COG0167	dihydroorotate dehydrogenase activity
ACO02_RS07690	COG3001	Fructosamine kinase
ACO02_RS07800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACO02_RS07800	COG2755	lipolytic protein G-D-S-L family
ACO02_RS07805	COG3942	CHAP domain
ACO02_RS07835	COG0436	Aminotransferase
ACO02_RS07880	COG2409	Drug exporters of the RND superfamily
ACO02_RS07900	COG0542	response to heat
ACO02_RS07905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACO02_RS07910	COG3425	synthase
ACO02_RS07935	COG3942	CHAP domain
ACO02_RS07945	COG0583	DNA-binding transcription factor activity
ACO02_RS07960	COG0028	Belongs to the TPP enzyme family
ACO02_RS07980	COG0657	acetylesterase activity
ACO02_RS07985	COG0697	spore germination
ACO02_RS08000	COG1760	l-serine dehydratase
ACO02_RS08005	COG1760	l-serine dehydratase
ACO02_RS08025	COG3764	Sortase (surface protein transpeptidase)
ACO02_RS08035	COG1131	(ABC) transporter
ACO02_RS08040	COG0561	phosphatase activity
ACO02_RS08055	COG2514	catechol 2,3-dioxygenase activity
ACO02_RS08065	COG1846	Transcriptional regulator
ACO02_RS08070	COG0346	lactoylglutathione lyase activity
ACO02_RS08075	COG0400	carboxylic ester hydrolase activity
ACO02_RS08080	COG3949	Membrane
ACO02_RS08095	COG1131	(ABC) transporter
ACO02_RS08110	COG1846	Transcriptional regulator
ACO02_RS08115	COG2814	Major facilitator Superfamily
ACO02_RS08125	COG0586	Pfam SNARE associated Golgi protein
ACO02_RS08130	COG2271	Major facilitator Superfamily
ACO02_RS08140	COG4876	unkown
ACO02_RS08145	COG2357	RelA SpoT domain protein
ACO02_RS08150	COG0789	Transcriptional regulator
ACO02_RS08155	COG1802	Transcriptional regulator
ACO02_RS08160	COG1070	Carbohydrate kinase
ACO02_RS08195	COG1846	Transcriptional regulator
ACO02_RS08200	COG1846	Transcriptional regulator
ACO02_RS08240	COG0494	nUDIX hydrolase
ACO02_RS08330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACO02_RS08335	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACO02_RS08365	COG0747	negative chemotaxis
ACO02_RS08370	COG0601	transmembrane transport
ACO02_RS08375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACO02_RS08380	COG0444	Belongs to the ABC transporter superfamily
ACO02_RS08385	COG1124	(ABC) transporter
ACO02_RS08400	COG0069	glutamate synthase activity
ACO02_RS08405	COG4808	Protein conserved in bacteria
ACO02_RS08425	COG1363	Peptidase, m42
ACO02_RS08430	COG4619	ABC transporter
ACO02_RS08435	COG0390	transport system, permease component
ACO02_RS08440	COG2814	Major facilitator Superfamily
ACO02_RS08445	COG2272	Belongs to the type-B carboxylesterase lipase family
ACO02_RS08450	COG0531	amino acid
ACO02_RS08460	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ACO02_RS08480	COG1174	glycine betaine transport
ACO02_RS08490	COG1174	glycine betaine transport
ACO02_RS08500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACO02_RS08525	COG0531	amino acid
ACO02_RS08540	COG1113	amino acid transport
ACO02_RS08560	COG2814	Major facilitator Superfamily
ACO02_RS08570	COG1929	Belongs to the glycerate kinase type-1 family
ACO02_RS08590	COG1132	(ABC) transporter
ACO02_RS08590	COG2375	cellular response to nickel ion
ACO02_RS08595	COG1132	(ABC) transporter
ACO02_RS08610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACO02_RS08615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACO02_RS08625	COG0156	8-amino-7-oxononanoate synthase activity
ACO02_RS08675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACO02_RS08695	COG2814	Major facilitator Superfamily
ACO02_RS08700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACO02_RS08705	COG0765	amino acid transport
ACO02_RS08710	COG1126	abc transporter atp-binding protein
ACO02_RS08750	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACO02_RS08750	COG3443	Belongs to the bacterial solute-binding protein 9 family
ACO02_RS08765	COG2116	formate transmembrane transporter activity
ACO02_RS08770	COG0454	-acetyltransferase
ACO02_RS08780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACO02_RS08785	COG2146	nitrite reductase [NAD(P)H] activity
ACO02_RS08795	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ACO02_RS08800	COG1140	nitrate reductase beta subunit
ACO02_RS08810	COG2181	nitrate reductase activity
ACO02_RS08830	COG0789	Transcriptional regulator
ACO02_RS08870	COG3871	stress protein (general stress protein 26)
ACO02_RS08885	COG1263	PTS System
ACO02_RS08885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACO02_RS08900	COG1511	domain protein
ACO02_RS08925	COG0456	acetyltransferase
ACO02_RS08930	COG0604	alcohol dehydrogenase
ACO02_RS08950	COG1620	l-lactate permease
ACO02_RS09020	COG2814	Major facilitator Superfamily
ACO02_RS09030	COG1566	PFAM secretion protein HlyD family protein
ACO02_RS09035	COG2814	Major facilitator Superfamily
ACO02_RS09045	COG0657	acetylesterase activity
ACO02_RS09060	COG0598	Magnesium transport protein CorA
ACO02_RS09070	COG0786	glutamate:sodium symporter activity
ACO02_RS09085	COG3152	Membrane
ACO02_RS09090	COG4152	abc transporter atp-binding protein
ACO02_RS09095	COG1668	transmembrane transport
ACO02_RS09115	COG2258	MOSC domain
ACO02_RS09140	COG0583	DNA-binding transcription factor activity
ACO02_RS09155	COG1473	amidohydrolase
ACO02_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
ACO02_RS09180	COG1737	Transcriptional regulator
ACO02_RS09185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACO02_RS09185	COG1263	PTS System
ACO02_RS09195	COG0385	Bile acid
ACO02_RS09200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACO02_RS09220	COG1113	amino acid transport
ACO02_RS09295	COG3942	CHAP domain
ACO02_RS09310	COG1757	Na H antiporter
ACO02_RS09320	COG3942	CHAP domain
ACO02_RS09385	COG4413	Urea transporter
ACO02_RS09390	COG1960	acyl-CoA dehydrogenase activity
ACO02_RS09405	COG1268	BioY protein
ACO02_RS09420	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACO02_RS09425	COG4149	molybdate abc transporter
ACO02_RS09430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACO02_RS09435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACO02_RS09455	COG1763	Mo-molybdopterin cofactor biosynthetic process
ACO02_RS09530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACO02_RS09575	COG2252	PERMEase
ACO02_RS09690	COG0201	protein transport
ACO02_RS09775	COG0542	response to heat
ACO02_RS09795	COG0028	Belongs to the TPP enzyme family
ACO02_RS09800	COG3527	Alpha-acetolactate decarboxylase
ACO02_RS09820	COG5492	domain, Protein
ACO02_RS09830	COG0789	Transcriptional regulator
ACO02_RS09835	COG0656	L-ascorbic acid biosynthetic process
ACO02_RS09855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACO02_RS09905	COG2130	NADP-dependent
ACO02_RS09915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACO02_RS09945	COG2814	Major facilitator Superfamily
ACO02_RS09950	COG4264	IucA IucC family
ACO02_RS09955	COG3457	Alanine racemase
ACO02_RS09965	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ACO02_RS09970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACO02_RS09975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACO02_RS09980	COG3314	Sporulation integral membrane protein YlbJ
ACO02_RS09990	COG1988	membrane-bound metal-dependent
ACO02_RS10000	COG1272	protein, Hemolysin III
ACO02_RS10015	COG2814	Major facilitator Superfamily
ACO02_RS10020	COG0489	protein tyrosine kinase activity
ACO02_RS10095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ACO02_RS10125	COG3711	transcriptional antiterminator
ACO02_RS10140	COG1119	ATPase activity
ACO02_RS10145	COG0561	phosphatase activity
ACO02_RS10180	COG0640	Transcriptional regulator
ACO02_RS10185	COG0702	epimerase
ACO02_RS10190	COG1482	cell wall glycoprotein biosynthetic process
ACO02_RS10210	COG0783	Belongs to the Dps family
ACO02_RS10215	COG0813	purine-nucleoside phosphorylase activity
ACO02_RS10265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACO02_RS10305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACO02_RS10330	COG2890	protein-(glutamine-N5) methyltransferase activity
ACO02_RS10335	COG0009	L-threonylcarbamoyladenylate synthase
ACO02_RS10360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACO02_RS10435	COG0629	single-stranded DNA binding
ACO02_RS10485	COG1418	mRNA catabolic process
ACO02_RS10495	COG1937	Protein conserved in bacteria
ACO02_RS10510	COG0772	Belongs to the SEDS family
ACO02_RS10520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACO02_RS10530	COG0745	RESPONSE REGULATOR receiver
ACO02_RS10535	COG2205	protein histidine kinase activity
ACO02_RS10565	COG3428	Bacterial PH domain
ACO02_RS10600	COG2208	phosphoserine phosphatase activity
ACO02_RS10605	COG1366	Belongs to the anti-sigma-factor antagonist family
ACO02_RS10615	COG1191	sigma factor activity
ACO02_RS10620	COG2183	response to ionizing radiation
ACO02_RS10695	COG0028	Belongs to the TPP enzyme family
ACO02_RS10710	COG0802	atpase or kinase
ACO02_RS10715	COG1214	PFAM Peptidase M22, glycoprotease
ACO02_RS10720	COG0456	acetyltransferase
ACO02_RS10730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACO02_RS10740	COG0488	(ABC) transporter
ACO02_RS10750	COG2391	methyltransferase activity
ACO02_RS10755	COG0425	Belongs to the sulfur carrier protein TusA family
ACO02_RS10760	COG0004	ammonium transporteR
ACO02_RS10765	COG1609	Transcriptional regulator
ACO02_RS10770	COG1621	beta-fructofuranosidase activity
ACO02_RS10775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACO02_RS10850	COG5484	DNA packaging
ACO02_RS10850	COG3728	DNA packaging
ACO02_RS10870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACO02_RS10875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACO02_RS10880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACO02_RS10930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACO02_RS11105	COG0740	serine-type endopeptidase activity
ACO02_RS11155	COG0739	heme binding
ACO02_RS11200	COG5632	N-Acetylmuramoyl-L-alanine amidase
ACO02_RS11200	COG1388	LysM domain
ACO02_RS11275	COG1725	Transcriptional regulator
ACO02_RS11290	COG1131	(ABC) transporter
ACO02_RS11345	COG1012	belongs to the aldehyde dehydrogenase family
ACO02_RS11360	COG1335	isochorismatase
ACO02_RS11380	COG0077	Prephenate dehydratase
ACO02_RS11390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACO02_RS11430	COG4496	protein, YerC YecD
ACO02_RS11440	COG0210	DNA helicase
ACO02_RS11450	COG4851	CamS sex pheromone cAM373 precursor
ACO02_RS11580	COG2197	response regulator
ACO02_RS11585	COG1295	ribonuclease BN
ACO02_RS11605	COG2309	aminopeptidase activity
ACO02_RS11610	COG1607	acyl-coa hydrolase
ACO02_RS11615	COG0535	radical SAM domain protein
ACO02_RS11645	COG1388	LysM domain
ACO02_RS11645	COG1134	teichoic acid transport
ACO02_RS11660	COG1988	membrane-bound metal-dependent
ACO02_RS11685	COG4129	membrane
ACO02_RS11695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACO02_RS11700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACO02_RS11880	COG0765	amino acid transport
ACO02_RS11885	COG1126	abc transporter atp-binding protein
ACO02_RS11890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACO02_RS11930	COG0564	pseudouridine synthase activity
ACO02_RS11935	COG2203	Gaf domain
ACO02_RS11935	COG4585	Histidine kinase
ACO02_RS11940	COG2197	response regulator
ACO02_RS11970	COG0420	3'-5' exonuclease activity
ACO02_RS12005	COG0537	adenosine 5'-monophosphoramidase activity
ACO02_RS12010	COG1131	(ABC) transporter
ACO02_RS12040	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ACO02_RS12160	COG1131	(ABC) transporter
ACO02_RS12340	COG1506	peptidase
ACO02_RS12365	COG0656	L-ascorbic acid biosynthetic process
ACO02_RS12390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACO02_RS12420	COG3266	domain, Protein
ACO02_RS12420	COG4193	domain, Protein
ACO02_RS12420	COG5632	N-Acetylmuramoyl-L-alanine amidase
ACO02_RS12445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACO02_RS12445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACO02_RS12480	COG2267	carboxylic ester hydrolase activity
ACO02_RS12495	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ACO02_RS12500	COG1242	4 iron, 4 sulfur cluster binding
ACO02_RS12505	COG2814	Major facilitator Superfamily
ACO02_RS12525	COG2081	HI0933 family
ACO02_RS12530	COG2244	polysaccharide biosynthetic process
ACO02_RS12535	COG1187	pseudouridine synthase activity
ACO02_RS12560	COG0510	thiamine kinase activity
ACO02_RS12570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACO02_RS12580	COG1363	Peptidase, m42
ACO02_RS12585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACO02_RS12595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACO02_RS12600	COG1674	ftsk spoiiie
ACO02_RS12625	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ACO02_RS12625	COG1605	Chorismate mutase
ACO02_RS12645	COG0454	-acetyltransferase
ACO02_RS12650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACO02_RS12680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACO02_RS12685	COG0204	Acyl-transferase
ACO02_RS12690	COG1263	PTS System
ACO02_RS12690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACO02_RS12705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACO02_RS12710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACO02_RS12715	COG1764	response to oxidative stress
ACO02_RS12720	COG0584	glycerophosphoryl diester phosphodiesterase
ACO02_RS12740	COG1956	GAF domain-containing protein
ACO02_RS12755	COG1104	cysteine desulfurase activity
ACO02_RS12775	COG0827	DNA restriction-modification system
ACO02_RS12815	COG4109	DRTGG domain
ACO02_RS12825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACO02_RS12835	COG0281	malic enzyme
ACO02_RS12865	COG1113	amino acid transport
ACO02_RS12870	COG0372	Belongs to the citrate synthase family
ACO02_RS12885	COG0745	RESPONSE REGULATOR receiver
ACO02_RS12890	COG5002	protein histidine kinase activity
ACO02_RS12900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACO02_RS12900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACO02_RS12930	COG1484	DNA-dependent DNA replication
ACO02_RS12945	COG0833	amino acid
ACO02_RS12970	COG4112	unkown
ACO02_RS13005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACO02_RS13040	COG2818	Glycosylase
ACO02_RS13050	COG0285	dihydrofolate synthase activity
ACO02_RS13060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACO02_RS13105	COG2868	ribosomal protein
ACO02_RS13145	COG1862	Preprotein translocase
ACO02_RS13150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACO02_RS13150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACO02_RS13155	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACO02_RS13155	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ACO02_RS13200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACO02_RS13205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACO02_RS13210	COG1959	2 iron, 2 sulfur cluster binding
ACO02_RS13225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACO02_RS13230	COG1104	cysteine desulfurase activity
ACO02_RS13245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACO02_RS13275	COG0826	peptidase U32
ACO02_RS13280	COG0826	peptidase U32
ACO02_RS13295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ACO02_RS13300	COG1984	allophanate hydrolase subunit 2
ACO02_RS13305	COG0511	ligase activity, forming carbon-carbon bonds
ACO02_RS13310	COG0439	Biotin carboxylase
ACO02_RS13320	COG1914	H( )-stimulated, divalent metal cation uptake system
ACO02_RS13325	COG3177	Filamentation induced by cAMP protein fic
ACO02_RS13345	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ACO02_RS13350	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ACO02_RS13360	COG1534	Rna-binding protein
ACO02_RS13370	COG1713	HD superfamily hydrolase involved in NAD metabolism
ACO02_RS13375	COG0799	negative regulation of ribosome biogenesis
ACO02_RS13380	COG2226	methyltransferase
ACO02_RS13390	COG2131	deaminase
ACO02_RS13395	COG0658	competence protein
ACO02_RS13395	COG2333	competence protein COMEC
ACO02_RS13400	COG1466	dna polymerase III delta subunit
ACO02_RS13420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACO02_RS13450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACO02_RS13455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACO02_RS13465	COG1030	water channel activity
ACO02_RS13480	COG1702	phosphate starvation-inducible protein PhoH
ACO02_RS13495	COG0295	cytidine deaminase activity
ACO02_RS13515	COG0517	IMP dehydrogenase activity
ACO02_RS13535	COG2384	SAM-dependent methyltransferase
ACO02_RS13545	COG0513	Belongs to the DEAD box helicase family
ACO02_RS13555	COG1121	(ABC) transporter
ACO02_RS13560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACO02_RS13575	COG0768	penicillin binding
ACO02_RS13585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACO02_RS13595	COG4483	Protein conserved in bacteria
ACO02_RS13600	COG1940	carbohydrate kinase activity
ACO02_RS13605	COG0011	TIGRFAM Protein of
ACO02_RS13610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACO02_RS13615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACO02_RS13620	COG1459	type II secretion system
ACO02_RS13625	COG4537	Required for transformation and DNA binding
ACO02_RS13670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACO02_RS13675	COG0095	Lipoate-protein ligase
ACO02_RS13690	COG0006	proline dipeptidase activity
ACO02_RS13700	COG0511	ligase activity, forming carbon-carbon bonds
ACO02_RS13705	COG0439	Biotin carboxylase
ACO02_RS13710	COG1302	Protein conserved in bacteria
ACO02_RS13740	COG0497	DNA recombination
ACO02_RS13745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACO02_RS13750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACO02_RS13755	COG0022	dehydrogenase e1 component
ACO02_RS13760	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACO02_RS13770	COG4129	membrane
ACO02_RS13780	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACO02_RS13800	COG1609	Transcriptional regulator
ACO02_RS13805	COG0366	Alpha amylase catalytic
ACO02_RS13815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACO02_RS13830	COG4221	oxidoreductase activity
ACO02_RS13840	COG0667	Aldo Keto reductase
ACO02_RS13845	COG0494	nUDIX hydrolase
ACO02_RS13850	COG0735	belongs to the Fur family
ACO02_RS13875	COG1187	pseudouridine synthase activity
ACO02_RS13880	COG0745	RESPONSE REGULATOR receiver
ACO02_RS13885	COG5002	protein histidine kinase activity
ACO02_RS13905	COG0582	viral genome integration into host DNA
ACO02_RS14165	COG3953	SLT domain
ACO02_RS14165	COG5280	Phage tail tape measure protein TP901
ACO02_RS14215	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACO02_RS14215	COG1388	LysM domain
ACO02_RS14265	COG1141	Ferredoxin
ACO02_RS14275	COG0514	ATP-dependent DNA helicase (RecQ)
ACO02_RS14290	COG0492	ferredoxin-NADP+ reductase activity
ACO02_RS14355	COG0142	geranyltranstransferase activity
ACO02_RS14395	COG4347	Protein of unknown function (DUF1405)
ACO02_RS14400	COG2738	Putative neutral zinc metallopeptidase
ACO02_RS14405	COG1694	Mazg nucleotide pyrophosphohydrolase
ACO02_RS14410	COG0438	transferase activity, transferring glycosyl groups
ACO02_RS14435	COG3935	DnaD domain protein
ACO02_RS14440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACO02_RS14450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACO02_RS14450	COG4499	WXG100 protein secretion system (Wss), protein YukC
ACO02_RS14490	COG0116	Belongs to the methyltransferase superfamily
ACO02_RS14505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ACO02_RS14510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACO02_RS14525	COG0531	amino acid
ACO02_RS14550	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACO02_RS14625	COG0671	phosphoesterase, PA-phosphatase related
ACO02_RS14680	COG4548	von Willebrand factor, type A
ACO02_RS14760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACO02_RS14765	COG0527	aspartate kinase activity
ACO02_RS14770	COG0488	(ABC) transporter
ACO02_RS14790	COG0573	inorganic phosphate transmembrane transporter activity
ACO02_RS14795	COG0581	inorganic phosphate transmembrane transporter activity
ACO02_RS14805	COG0704	Plays a role in the regulation of phosphate uptake
ACO02_RS14850	COG0561	phosphatase activity
ACO02_RS14890	COG0512	Glutamine amidotransferase of anthranilate synthase
ACO02_RS14895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACO02_RS14900	COG1363	Peptidase, m42
ACO02_RS14910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACO02_RS14930	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACO02_RS14930	COG0392	lysyltransferase activity
ACO02_RS14935	COG0628	permease
ACO02_RS14950	COG1115	amino acid carrier protein
ACO02_RS14990	COG0824	Thioesterase
ACO02_RS15085	COG0551	DNA topoisomerase type I activity
ACO02_RS15085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACO02_RS15100	COG0551	DNA topoisomerase type I activity
ACO02_RS15160	COG1131	(ABC) transporter
ACO02_RS15170	COG3173	Aminoglycoside phosphotransferase
ACO02_RS15245	COG0604	alcohol dehydrogenase
ACO02_RS15270	COG3682	Transcriptional regulator