locus-tag	class	description
AS858_RS00005	COG4166	transmembrane transport
AS858_RS00110	COG4608	Belongs to the ABC transporter superfamily
AS858_RS00245	COG4166	transmembrane transport
AS858_RS00410	COG0542	response to heat
AS858_RS00520	COG4608	Belongs to the ABC transporter superfamily
AS858_RS00610	COG0628	permease
AS858_RS00770	COG0601	transmembrane transport
AS858_RS00785	COG0561	phosphatase activity
AS858_RS00810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS858_RS00825	COG1881	PFAM PEBP family protein
AS858_RS00855	COG0601	transmembrane transport
AS858_RS00860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS858_RS00865	COG0444	Belongs to the ABC transporter superfamily
AS858_RS00870	COG4608	Belongs to the ABC transporter superfamily
AS858_RS00875	COG4166	transmembrane transport
AS858_RS00885	COG0444	Belongs to the ABC transporter superfamily
AS858_RS00890	COG4608	Belongs to the ABC transporter superfamily
AS858_RS00895	COG0601	transmembrane transport
AS858_RS00900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS858_RS00925	COG1164	Oligoendopeptidase f
AS858_RS00935	COG2346	COG2346, Truncated hemoglobins
AS858_RS00950	COG2357	RelA SpoT domain protein
AS858_RS00960	COG0564	pseudouridine synthase activity
AS858_RS00965	COG2239	Acts as a magnesium transporter
AS858_RS00970	COG0475	glutathione-regulated potassium exporter activity
AS858_RS00970	COG0569	domain protein
AS858_RS00980	COG0628	permease
AS858_RS00985	COG1115	amino acid carrier protein
AS858_RS01025	COG0861	Integral membrane protein TerC family
AS858_RS01035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS858_RS01040	COG0737	Belongs to the 5'-nucleotidase family
AS858_RS01055	COG4903	ComK protein
AS858_RS01070	COG4873	Protein conserved in bacteria
AS858_RS01125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS858_RS01135	COG2314	TM2 domain
AS858_RS01140	COG0456	acetyltransferase
AS858_RS01145	COG1575	Belongs to the MenA family. Type 1 subfamily
AS858_RS01150	COG1169	isochorismate synthase
AS858_RS01160	COG2267	carboxylic ester hydrolase activity
AS858_RS01185	COG0436	Aminotransferase
AS858_RS01190	COG3594	Acyltransferase
AS858_RS01220	COG1316	TRANSCRIPTIONal
AS858_RS01225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS858_RS01265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AS858_RS01280	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS858_RS01320	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS858_RS01325	COG4172	Belongs to the ABC transporter superfamily
AS858_RS01330	COG4721	ABC-type cobalt transport system, permease component
AS858_RS01350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS858_RS01375	COG1271	oxidase subunit
AS858_RS01380	COG1294	oxidase, subunit
AS858_RS01385	COG0569	domain protein
AS858_RS01455	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS858_RS01460	COG1177	transmembrane transport
AS858_RS01465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AS858_RS01490	COG0483	inositol monophosphate 1-phosphatase activity
AS858_RS01500	COG1217	gtp-binding protein TYPA
AS858_RS01510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS858_RS01520	COG0772	Belongs to the SEDS family
AS858_RS01555	COG3679	Belongs to the UPF0342 family
AS858_RS01575	COG0742	ribosomal rna small subunit methyltransferase
AS858_RS01640	COG4509	Sortase family
AS858_RS01655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS858_RS01685	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS858_RS01685	COG1796	DNA polymerase
AS858_RS01710	COG2009	succinate dehydrogenase
AS858_RS01715	COG1053	succinate dehydrogenase
AS858_RS01720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS858_RS01840	COG1288	antiporter activity
AS858_RS01875	COG1011	Hydrolase
AS858_RS01900	COG4839	cell division protein FtsL
AS858_RS01905	COG0768	penicillin binding
AS858_RS01920	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS858_RS01925	COG0849	cell division
AS858_RS01940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AS858_RS01950	COG0762	integral membrane protein
AS858_RS01955	COG2302	S4 RNA-binding domain
AS858_RS01960	COG3599	regulation of cell shape
AS858_RS01970	COG2514	catechol 2,3-dioxygenase activity
AS858_RS01985	COG0564	pseudouridine synthase activity
AS858_RS01995	COG2233	PERMEase
AS858_RS02040	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AS858_RS02055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS858_RS02060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS858_RS02070	COG2314	TM2 domain
AS858_RS02085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AS858_RS02085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS858_RS02095	COG0631	protein serine/threonine phosphatase activity
AS858_RS02110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS858_RS02125	COG1302	Protein conserved in bacteria
AS858_RS02135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AS858_RS02175	COG1196	nuclear chromosome segregation
AS858_RS02180	COG0552	protein localization to endoplasmic reticulum
AS858_RS02190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS858_RS02255	COG0758	DNA mediated transformation
AS858_RS02350	COG0195	Participates in both transcription termination and antitermination
AS858_RS02355	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AS858_RS02380	COG0196	riboflavin kinase activity
AS858_RS02405	COG2188	Transcriptional regulator
AS858_RS02410	COG0612	Peptidase, M16
AS858_RS02415	COG0612	Peptidase, M16
AS858_RS02420	COG0300	oxidoreductase activity
AS858_RS02440	COG1058	Belongs to the CinA family
AS858_RS02440	COG1546	Belongs to the CinA family
AS858_RS02460	COG1692	metallophosphoesterase
AS858_RS02465	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS858_RS02465	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AS858_RS02470	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS858_RS02505	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AS858_RS02510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS858_RS02535	COG1923	regulation of RNA biosynthetic process
AS858_RS02545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS858_RS02550	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AS858_RS02555	COG0789	Transcriptional regulator
AS858_RS02675	COG1131	(ABC) transporter
AS858_RS02690	COG2197	response regulator
AS858_RS02700	COG1525	nuclease
AS858_RS02715	COG0527	aspartate kinase activity
AS858_RS02720	COG0460	homoserine dehydrogenase
AS858_RS02725	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS858_RS02750	COG0833	amino acid
AS858_RS02780	COG2340	Cysteine-rich secretory protein family
AS858_RS02815	COG4846	Membrane protein involved in cytochrome C biogenesis
AS858_RS02835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS858_RS02845	COG0824	Thioesterase
AS858_RS02875	COG1115	amino acid carrier protein
AS858_RS02890	COG0628	permease
AS858_RS02895	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS858_RS02895	COG0392	lysyltransferase activity
AS858_RS02915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS858_RS02925	COG1363	Peptidase, m42
AS858_RS02930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS858_RS02935	COG0512	Glutamine amidotransferase of anthranilate synthase
AS858_RS02975	COG0561	phosphatase activity
AS858_RS03020	COG0704	Plays a role in the regulation of phosphate uptake
AS858_RS03030	COG0581	inorganic phosphate transmembrane transporter activity
AS858_RS03035	COG0573	inorganic phosphate transmembrane transporter activity
AS858_RS03060	COG0488	(ABC) transporter
AS858_RS03065	COG0527	aspartate kinase activity
AS858_RS03070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS858_RS03155	COG4548	von Willebrand factor, type A
AS858_RS03210	COG0671	phosphoesterase, PA-phosphatase related
AS858_RS03290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AS858_RS03320	COG0531	amino acid
AS858_RS03335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS858_RS03340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS858_RS03360	COG0116	Belongs to the methyltransferase superfamily
AS858_RS03395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS858_RS03395	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS858_RS03405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AS858_RS03410	COG3935	DnaD domain protein
AS858_RS03435	COG0438	transferase activity, transferring glycosyl groups
AS858_RS03440	COG1694	Mazg nucleotide pyrophosphohydrolase
AS858_RS03445	COG2738	Putative neutral zinc metallopeptidase
AS858_RS03450	COG4347	Protein of unknown function (DUF1405)
AS858_RS03490	COG0142	geranyltranstransferase activity
AS858_RS03555	COG0492	ferredoxin-NADP+ reductase activity
AS858_RS03570	COG0514	ATP-dependent DNA helicase (RecQ)
AS858_RS03580	COG1141	Ferredoxin
AS858_RS03630	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS858_RS03630	COG1388	LysM domain
AS858_RS03680	COG3953	SLT domain
AS858_RS03680	COG5280	Phage tail tape measure protein TP901
AS858_RS03935	COG0582	viral genome integration into host DNA
AS858_RS03950	COG5002	protein histidine kinase activity
AS858_RS03955	COG0745	RESPONSE REGULATOR receiver
AS858_RS03960	COG1187	pseudouridine synthase activity
AS858_RS03985	COG0735	belongs to the Fur family
AS858_RS03990	COG0494	nUDIX hydrolase
AS858_RS03995	COG0667	Aldo Keto reductase
AS858_RS04005	COG4221	oxidoreductase activity
AS858_RS04020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS858_RS04030	COG0366	Alpha amylase catalytic
AS858_RS04035	COG1609	Transcriptional regulator
AS858_RS04055	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS858_RS04065	COG4129	membrane
AS858_RS04075	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS858_RS04080	COG0022	dehydrogenase e1 component
AS858_RS04085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS858_RS04090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS858_RS04095	COG0497	DNA recombination
AS858_RS04125	COG1302	Protein conserved in bacteria
AS858_RS04130	COG0439	Biotin carboxylase
AS858_RS04135	COG0511	ligase activity, forming carbon-carbon bonds
AS858_RS04145	COG0006	proline dipeptidase activity
AS858_RS04160	COG0095	Lipoate-protein ligase
AS858_RS04165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS858_RS04210	COG4537	Required for transformation and DNA binding
AS858_RS04215	COG1459	type II secretion system
AS858_RS04220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AS858_RS04225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS858_RS04230	COG0011	TIGRFAM Protein of
AS858_RS04235	COG1940	carbohydrate kinase activity
AS858_RS04240	COG4483	Protein conserved in bacteria
AS858_RS04250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS858_RS04260	COG0768	penicillin binding
AS858_RS04275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS858_RS04280	COG1121	(ABC) transporter
AS858_RS04290	COG0513	Belongs to the DEAD box helicase family
AS858_RS04300	COG2384	SAM-dependent methyltransferase
AS858_RS04320	COG0517	IMP dehydrogenase activity
AS858_RS04340	COG0295	cytidine deaminase activity
AS858_RS04355	COG1702	phosphate starvation-inducible protein PhoH
AS858_RS04370	COG1030	water channel activity
AS858_RS04380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS858_RS04385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AS858_RS04415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS858_RS04435	COG1466	dna polymerase III delta subunit
AS858_RS04440	COG2333	competence protein COMEC
AS858_RS04440	COG0658	competence protein
AS858_RS04445	COG2131	deaminase
AS858_RS04455	COG2226	methyltransferase
AS858_RS04460	COG0799	negative regulation of ribosome biogenesis
AS858_RS04465	COG1713	HD superfamily hydrolase involved in NAD metabolism
AS858_RS04475	COG1534	Rna-binding protein
AS858_RS04485	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS858_RS04490	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AS858_RS04515	COG3177	Filamentation induced by cAMP protein fic
AS858_RS04520	COG1914	H( )-stimulated, divalent metal cation uptake system
AS858_RS04530	COG0439	Biotin carboxylase
AS858_RS04535	COG0511	ligase activity, forming carbon-carbon bonds
AS858_RS04540	COG1984	allophanate hydrolase subunit 2
AS858_RS04545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS858_RS04560	COG0826	peptidase U32
AS858_RS04565	COG0826	peptidase U32
AS858_RS04595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS858_RS04610	COG1104	cysteine desulfurase activity
AS858_RS04615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS858_RS04630	COG1959	2 iron, 2 sulfur cluster binding
AS858_RS04635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AS858_RS04640	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AS858_RS04685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AS858_RS04685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS858_RS04690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS858_RS04690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS858_RS04695	COG1862	Preprotein translocase
AS858_RS04735	COG2868	ribosomal protein
AS858_RS04775	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AS858_RS04785	COG0285	dihydrofolate synthase activity
AS858_RS04795	COG2818	Glycosylase
AS858_RS04830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS858_RS04865	COG4112	unkown
AS858_RS04890	COG0833	amino acid
AS858_RS04905	COG1484	DNA-dependent DNA replication
AS858_RS04935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS858_RS04935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS858_RS04945	COG5002	protein histidine kinase activity
AS858_RS04950	COG0745	RESPONSE REGULATOR receiver
AS858_RS04965	COG0372	Belongs to the citrate synthase family
AS858_RS04970	COG1113	amino acid transport
AS858_RS05005	COG0281	malic enzyme
AS858_RS05015	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AS858_RS05020	COG4109	DRTGG domain
AS858_RS05060	COG0827	DNA restriction-modification system
AS858_RS05080	COG1104	cysteine desulfurase activity
AS858_RS05095	COG1956	GAF domain-containing protein
AS858_RS05110	COG0584	glycerophosphoryl diester phosphodiesterase
AS858_RS05115	COG1764	response to oxidative stress
AS858_RS05120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AS858_RS05125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS858_RS05140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS858_RS05140	COG1263	PTS System
AS858_RS05145	COG0204	Acyl-transferase
AS858_RS05150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS858_RS05180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS858_RS05185	COG0454	-acetyltransferase
AS858_RS05205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AS858_RS05205	COG1605	Chorismate mutase
AS858_RS05230	COG1674	ftsk spoiiie
AS858_RS05235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS858_RS05245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS858_RS05250	COG1363	Peptidase, m42
AS858_RS05260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS858_RS05270	COG0510	thiamine kinase activity
AS858_RS05290	COG1187	pseudouridine synthase activity
AS858_RS05295	COG2244	polysaccharide biosynthetic process
AS858_RS05300	COG2081	HI0933 family
AS858_RS05320	COG2814	Major facilitator Superfamily
AS858_RS05325	COG1242	4 iron, 4 sulfur cluster binding
AS858_RS05330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AS858_RS05350	COG2267	carboxylic ester hydrolase activity
AS858_RS05380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS858_RS05380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS858_RS05405	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS858_RS05405	COG3266	domain, Protein
AS858_RS05405	COG4193	domain, Protein
AS858_RS05435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS858_RS05465	COG0656	L-ascorbic acid biosynthetic process
AS858_RS05490	COG1506	peptidase
AS858_RS05655	COG1131	(ABC) transporter
AS858_RS05760	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AS858_RS05790	COG1131	(ABC) transporter
AS858_RS05795	COG0537	adenosine 5'-monophosphoramidase activity
AS858_RS05825	COG0420	3'-5' exonuclease activity
AS858_RS05850	COG2197	response regulator
AS858_RS05855	COG4585	Histidine kinase
AS858_RS05855	COG2203	Gaf domain
AS858_RS05860	COG0564	pseudouridine synthase activity
AS858_RS05895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AS858_RS05900	COG1126	abc transporter atp-binding protein
AS858_RS05905	COG0765	amino acid transport
AS858_RS06075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS858_RS06080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS858_RS06090	COG4129	membrane
AS858_RS06115	COG1988	membrane-bound metal-dependent
AS858_RS06130	COG1388	LysM domain
AS858_RS06130	COG1134	teichoic acid transport
AS858_RS06160	COG0535	radical SAM domain protein
AS858_RS06165	COG1607	acyl-coa hydrolase
AS858_RS06170	COG2309	aminopeptidase activity
AS858_RS06190	COG1295	ribonuclease BN
AS858_RS06195	COG2197	response regulator
AS858_RS06310	COG4851	CamS sex pheromone cAM373 precursor
AS858_RS06320	COG0210	DNA helicase
AS858_RS06330	COG4496	protein, YerC YecD
AS858_RS06365	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AS858_RS06375	COG0077	Prephenate dehydratase
AS858_RS06395	COG1335	isochorismatase
AS858_RS06410	COG1012	belongs to the aldehyde dehydrogenase family
AS858_RS06460	COG1131	(ABC) transporter
AS858_RS06475	COG1725	Transcriptional regulator
AS858_RS06535	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS858_RS06535	COG1388	LysM domain
AS858_RS06545	COG1388	LysM domain
AS858_RS06545	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS858_RS06585	COG0739	heme binding
AS858_RS06630	COG0740	serine-type endopeptidase activity
AS858_RS06800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AS858_RS06850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS858_RS06855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS858_RS06860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS858_RS06875	COG5484	DNA packaging
AS858_RS06875	COG3728	DNA packaging
AS858_RS06950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS858_RS06955	COG1621	beta-fructofuranosidase activity
AS858_RS06960	COG1609	Transcriptional regulator
AS858_RS06965	COG0004	ammonium transporteR
AS858_RS06970	COG0425	Belongs to the sulfur carrier protein TusA family
AS858_RS06975	COG2391	methyltransferase activity
AS858_RS06985	COG0488	(ABC) transporter
AS858_RS06995	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AS858_RS07005	COG0456	acetyltransferase
AS858_RS07010	COG1214	PFAM Peptidase M22, glycoprotease
AS858_RS07015	COG0802	atpase or kinase
AS858_RS07030	COG0028	Belongs to the TPP enzyme family
AS858_RS07105	COG2183	response to ionizing radiation
AS858_RS07110	COG1191	sigma factor activity
AS858_RS07120	COG1366	Belongs to the anti-sigma-factor antagonist family
AS858_RS07125	COG2208	phosphoserine phosphatase activity
AS858_RS07160	COG3428	Bacterial PH domain
AS858_RS07190	COG2205	protein histidine kinase activity
AS858_RS07195	COG0745	RESPONSE REGULATOR receiver
AS858_RS07205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS858_RS07215	COG0772	Belongs to the SEDS family
AS858_RS07230	COG1937	Protein conserved in bacteria
AS858_RS07240	COG1418	mRNA catabolic process
AS858_RS07285	COG0629	single-stranded DNA binding
AS858_RS07360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS858_RS07385	COG0009	L-threonylcarbamoyladenylate synthase
AS858_RS07390	COG2890	protein-(glutamine-N5) methyltransferase activity
AS858_RS07410	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AS858_RS07450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS858_RS07505	COG0813	purine-nucleoside phosphorylase activity
AS858_RS07510	COG0783	Belongs to the Dps family
AS858_RS07530	COG1482	cell wall glycoprotein biosynthetic process
AS858_RS07535	COG0702	epimerase
AS858_RS07540	COG0640	Transcriptional regulator
AS858_RS07575	COG0561	phosphatase activity
AS858_RS07580	COG1119	ATPase activity
AS858_RS07595	COG3711	transcriptional antiterminator
AS858_RS07625	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS858_RS07695	COG0489	protein tyrosine kinase activity
AS858_RS07700	COG2814	Major facilitator Superfamily
AS858_RS07715	COG1272	protein, Hemolysin III
AS858_RS07725	COG1988	membrane-bound metal-dependent
AS858_RS07735	COG3314	Sporulation integral membrane protein YlbJ
AS858_RS07740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS858_RS07745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS858_RS07750	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS858_RS07760	COG3457	Alanine racemase
AS858_RS07765	COG4264	IucA IucC family
AS858_RS07770	COG2814	Major facilitator Superfamily
AS858_RS07810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS858_RS07820	COG2130	NADP-dependent
AS858_RS07870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS858_RS07890	COG0656	L-ascorbic acid biosynthetic process
AS858_RS07895	COG0789	Transcriptional regulator
AS858_RS07925	COG3527	Alpha-acetolactate decarboxylase
AS858_RS07930	COG0028	Belongs to the TPP enzyme family
AS858_RS07950	COG0542	response to heat
AS858_RS08040	COG0201	protein transport
AS858_RS08155	COG2252	PERMEase
AS858_RS08200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS858_RS08270	COG1763	Mo-molybdopterin cofactor biosynthetic process
AS858_RS08290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS858_RS08295	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AS858_RS08300	COG4149	molybdate abc transporter
AS858_RS08305	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS858_RS08320	COG1268	BioY protein
AS858_RS08335	COG1960	acyl-CoA dehydrogenase activity
AS858_RS08340	COG4413	Urea transporter
AS858_RS08405	COG3942	CHAP domain
AS858_RS08415	COG1757	Na H antiporter
AS858_RS08430	COG3942	CHAP domain
AS858_RS08505	COG1113	amino acid transport
AS858_RS08525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS858_RS08530	COG0385	Bile acid
AS858_RS08540	COG1263	PTS System
AS858_RS08540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS858_RS08545	COG1737	Transcriptional regulator
AS858_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
AS858_RS08570	COG1473	amidohydrolase
AS858_RS08585	COG0583	DNA-binding transcription factor activity
AS858_RS08610	COG2258	MOSC domain
AS858_RS08630	COG1668	transmembrane transport
AS858_RS08635	COG4152	abc transporter atp-binding protein
AS858_RS08640	COG3152	Membrane
AS858_RS08650	COG0786	glutamate:sodium symporter activity
AS858_RS08660	COG0598	Magnesium transport protein CorA
AS858_RS08675	COG0657	acetylesterase activity
AS858_RS08685	COG2814	Major facilitator Superfamily
AS858_RS08690	COG1566	PFAM secretion protein HlyD family protein
AS858_RS08700	COG2814	Major facilitator Superfamily
AS858_RS08775	COG1620	l-lactate permease
AS858_RS08795	COG0604	alcohol dehydrogenase
AS858_RS08800	COG0456	acetyltransferase
AS858_RS08825	COG1511	domain protein
AS858_RS08840	COG1263	PTS System
AS858_RS08840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS858_RS08855	COG3871	stress protein (general stress protein 26)
AS858_RS08895	COG0789	Transcriptional regulator
AS858_RS08915	COG2181	nitrate reductase activity
AS858_RS08925	COG1140	nitrate reductase beta subunit
AS858_RS08930	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AS858_RS08940	COG2146	nitrite reductase [NAD(P)H] activity
AS858_RS08945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS858_RS08955	COG0454	-acetyltransferase
AS858_RS08960	COG2116	formate transmembrane transporter activity
AS858_RS08975	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS858_RS08975	COG3443	Belongs to the bacterial solute-binding protein 9 family
AS858_RS09010	COG1126	abc transporter atp-binding protein
AS858_RS09015	COG0765	amino acid transport
AS858_RS09020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS858_RS09025	COG2814	Major facilitator Superfamily
AS858_RS09045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS858_RS09090	COG0156	8-amino-7-oxononanoate synthase activity
AS858_RS09100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS858_RS09105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AS858_RS09120	COG1132	(ABC) transporter
AS858_RS09125	COG2375	cellular response to nickel ion
AS858_RS09125	COG1132	(ABC) transporter
AS858_RS09145	COG1929	Belongs to the glycerate kinase type-1 family
AS858_RS09155	COG2814	Major facilitator Superfamily
AS858_RS09175	COG1113	amino acid transport
AS858_RS09190	COG0531	amino acid
AS858_RS09215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS858_RS09225	COG1174	glycine betaine transport
AS858_RS09235	COG1174	glycine betaine transport
AS858_RS09255	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AS858_RS09260	COG0531	amino acid
AS858_RS09265	COG2272	Belongs to the type-B carboxylesterase lipase family
AS858_RS09270	COG2814	Major facilitator Superfamily
AS858_RS09275	COG0390	transport system, permease component
AS858_RS09280	COG4619	ABC transporter
AS858_RS09285	COG1363	Peptidase, m42
AS858_RS09305	COG4808	Protein conserved in bacteria
AS858_RS09310	COG0069	glutamate synthase activity
AS858_RS09325	COG1124	(ABC) transporter
AS858_RS09330	COG0444	Belongs to the ABC transporter superfamily
AS858_RS09335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS858_RS09340	COG0601	transmembrane transport
AS858_RS09345	COG0747	negative chemotaxis
AS858_RS09375	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AS858_RS09380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS858_RS09465	COG0494	nUDIX hydrolase
AS858_RS09500	COG3583	domain protein
AS858_RS09505	COG1846	Transcriptional regulator
AS858_RS09510	COG1846	Transcriptional regulator
AS858_RS09540	COG1070	Carbohydrate kinase
AS858_RS09545	COG1802	Transcriptional regulator
AS858_RS09550	COG0789	Transcriptional regulator
AS858_RS09555	COG2357	RelA SpoT domain protein
AS858_RS09560	COG4876	unkown
AS858_RS09570	COG2271	Major facilitator Superfamily
AS858_RS09575	COG0586	Pfam SNARE associated Golgi protein
AS858_RS09585	COG2814	Major facilitator Superfamily
AS858_RS09590	COG1846	Transcriptional regulator
AS858_RS09595	COG1131	(ABC) transporter
AS858_RS09615	COG3949	Membrane
AS858_RS09620	COG0400	carboxylic ester hydrolase activity
AS858_RS09625	COG0346	lactoylglutathione lyase activity
AS858_RS09630	COG1846	Transcriptional regulator
AS858_RS09640	COG2514	catechol 2,3-dioxygenase activity
AS858_RS09655	COG0561	phosphatase activity
AS858_RS09660	COG1131	(ABC) transporter
AS858_RS09670	COG3764	Sortase (surface protein transpeptidase)
AS858_RS09690	COG1760	l-serine dehydratase
AS858_RS09695	COG1760	l-serine dehydratase
AS858_RS09710	COG0697	spore germination
AS858_RS09715	COG0657	acetylesterase activity
AS858_RS09735	COG0028	Belongs to the TPP enzyme family
AS858_RS09750	COG0583	DNA-binding transcription factor activity
AS858_RS09760	COG3942	CHAP domain
AS858_RS09785	COG3425	synthase
AS858_RS09790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS858_RS09795	COG0542	response to heat
AS858_RS09815	COG2409	Drug exporters of the RND superfamily
AS858_RS09860	COG0436	Aminotransferase
AS858_RS09890	COG3942	CHAP domain
AS858_RS09895	COG2755	lipolytic protein G-D-S-L family
AS858_RS09895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AS858_RS10000	COG3001	Fructosamine kinase
AS858_RS10005	COG0167	dihydroorotate dehydrogenase activity
AS858_RS10055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS858_RS10060	COG3527	Alpha-acetolactate decarboxylase
AS858_RS10075	COG0531	amino acid
AS858_RS10105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS858_RS10125	COG1012	belongs to the aldehyde dehydrogenase family
AS858_RS10135	COG1510	regulation of RNA biosynthetic process
AS858_RS10145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS858_RS10170	COG2851	Citrate transporter
AS858_RS10185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS858_RS10195	COG0386	Belongs to the glutathione peroxidase family
AS858_RS10220	COG1136	(ABC) transporter
AS858_RS10225	COG2205	protein histidine kinase activity
AS858_RS10230	COG0745	RESPONSE REGULATOR receiver
AS858_RS10245	COG1785	Belongs to the alkaline phosphatase family
AS858_RS10250	COG1846	Transcriptional regulator
AS858_RS10295	COG1438	arginine binding
AS858_RS10315	COG3711	transcriptional antiterminator
AS858_RS10315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS858_RS10320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS858_RS10320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS858_RS10320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS858_RS10325	COG1482	cell wall glycoprotein biosynthetic process
AS858_RS10335	COG3942	CHAP domain
AS858_RS10335	COG1705	Flagellar rod assembly protein muramidase FlgJ
AS858_RS10340	COG1535	isochorismatase
AS858_RS10340	COG3433	isochorismatase activity
AS858_RS10355	COG0438	transferase activity, transferring glycosyl groups
AS858_RS10370	COG1073	alpha beta
AS858_RS10390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS858_RS10410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS858_RS10465	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AS858_RS10500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS858_RS10585	COG0471	metal ion transport
AS858_RS10590	COG2962	Rard protein
AS858_RS10600	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AS858_RS10615	COG1136	(ABC) transporter
AS858_RS10620	COG0577	efflux transmembrane transporter activity
AS858_RS10645	COG1278	Cold shock
AS858_RS10665	COG1475	DNA binding
AS858_RS10705	COG2501	S4 domain
AS858_RS10725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AS858_RS10750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS858_RS10760	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AS858_RS10770	COG0305	Participates in initiation and elongation during chromosome replication
AS858_RS10800	COG4863	YycH protein
AS858_RS10810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS858_RS10815	COG0737	Belongs to the 5'-nucleotidase family
AS858_RS10840	COG0584	glycerophosphoryl diester phosphodiesterase
AS858_RS10845	COG2030	dehydratase
AS858_RS10915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS858_RS10920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS858_RS10955	COG2801	Transposase and inactivated derivatives
AS858_RS10960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS858_RS10990	COG2801	Transposase and inactivated derivatives
AS858_RS11000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS858_RS11005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS858_RS11015	COG2235	arginine
AS858_RS11065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS858_RS11070	COG4172	Belongs to the ABC transporter superfamily
AS858_RS11075	COG1124	(ABC) transporter
AS858_RS11085	COG1388	LysM domain
AS858_RS11115	COG0730	response to heat
AS858_RS11120	COG1937	Protein conserved in bacteria
AS858_RS11125	COG2210	Belongs to the sulfur carrier protein TusA family
AS858_RS11130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS858_RS11165	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS858_RS11180	COG0583	DNA-binding transcription factor activity
AS858_RS11200	COG0823	Involved in the tonB-independent uptake of proteins
AS858_RS11235	COG1473	amidohydrolase
AS858_RS11245	COG1283	sodium-dependent phosphate transmembrane transporter activity
AS858_RS11250	COG4716	Myosin-crossreactive antigen
AS858_RS11255	COG0697	spore germination
AS858_RS11270	COG1620	l-lactate permease
AS858_RS11285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS858_RS11290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS858_RS11295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS858_RS11305	COG2423	ornithine cyclodeaminase activity
AS858_RS11310	COG4264	IucA IucC family
AS858_RS11315	COG2814	Major facilitator Superfamily
AS858_RS11320	COG4264	IucA IucC family
AS858_RS11325	COG4264	IucA IucC family
AS858_RS11335	COG0019	diaminopimelate decarboxylase activity
AS858_RS11340	COG1475	DNA binding
AS858_RS11370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS858_RS11375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS858_RS11380	COG0438	transferase activity, transferring glycosyl groups
AS858_RS11415	COG0813	purine-nucleoside phosphorylase activity
AS858_RS11420	COG2814	Major facilitator Superfamily
AS858_RS11440	COG3639	organic phosphonate transmembrane transporter activity
AS858_RS11460	COG0737	Belongs to the 5'-nucleotidase family
AS858_RS11490	COG1454	alcohol dehydrogenase
AS858_RS11490	COG1012	belongs to the aldehyde dehydrogenase family
AS858_RS11515	COG1086	Polysaccharide biosynthesis protein
AS858_RS11525	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS858_RS11555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS858_RS11565	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AS858_RS11570	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS858_RS11580	COG2832	Protein of unknown function (DUF454)
AS858_RS11615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS858_RS11620	COG1960	acyl-CoA dehydrogenase activity
AS858_RS11625	COG5609	conserved protein (DUF2294)
AS858_RS11675	COG1114	Component of the transport system for branched-chain amino acids
AS858_RS11680	COG1335	isochorismatase
AS858_RS11685	COG3961	Belongs to the TPP enzyme family
AS858_RS11715	COG1737	Transcriptional regulator
AS858_RS11750	COG0601	transmembrane transport
AS858_RS11755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS858_RS11765	COG0405	Gamma-glutamyltransferase
AS858_RS11785	COG3842	ATPase activity
AS858_RS11795	COG1175	transmembrane transport
AS858_RS11800	COG3833	ABC-type maltose transport systems, permease component
AS858_RS11805	COG0673	inositol 2-dehydrogenase activity
AS858_RS11810	COG0673	inositol 2-dehydrogenase activity
AS858_RS11820	COG1755	Isoprenylcysteine carboxyl methyltransferase
AS858_RS11885	COG0183	Belongs to the thiolase family
AS858_RS11895	COG1960	acyl-CoA dehydrogenase activity
AS858_RS11900	COG0318	PFAM AMP-dependent synthetase and ligase
AS858_RS11915	COG0747	negative chemotaxis
AS858_RS11920	COG3189	MarR family transcriptional regulator
AS858_RS11950	COG2190	(PTS) system
AS858_RS11950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS858_RS11950	COG1263	PTS System
AS858_RS11955	COG1957	nucleoside hydrolase
AS858_RS11975	COG3414	Phosphotransferase system galactitol-specific IIB component
AS858_RS11980	COG3775	system Galactitol-specific IIC component
AS858_RS11985	COG1063	alcohol dehydrogenase
AS858_RS11995	COG1063	alcohol dehydrogenase
AS858_RS12005	COG1063	alcohol dehydrogenase
AS858_RS12010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS858_RS12015	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS858_RS12025	COG1063	alcohol dehydrogenase
AS858_RS12030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS858_RS12065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS858_RS12070	COG2190	(PTS) system
AS858_RS12070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS858_RS12070	COG1263	PTS System
AS858_RS12075	COG2723	6-phospho-beta-galactosidase activity
AS858_RS12085	COG2226	methyltransferase
AS858_RS12145	COG1131	(ABC) transporter
AS858_RS12175	COG3942	CHAP domain
AS858_RS12175	COG1388	LysM domain
AS858_RS12320	COG1114	Component of the transport system for branched-chain amino acids
AS858_RS12325	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AS858_RS12335	COG0577	efflux transmembrane transporter activity
AS858_RS12360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS858_RS12365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS858_RS12390	COG3314	Sporulation integral membrane protein YlbJ
AS858_RS12415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS858_RS12445	COG3037	sugar-specific permease SgaT UlaA
AS858_RS12455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS858_RS12460	COG3711	transcriptional antiterminator
AS858_RS12480	COG2271	Major facilitator Superfamily
AS858_RS12485	COG0346	lactoylglutathione lyase activity
AS858_RS12490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS858_RS12495	COG0431	NADPH-dependent FMN reductase
AS858_RS12510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS858_RS12525	COG0672	)-iron permease
AS858_RS12530	COG0805	protein transport
AS858_RS12535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS858_RS12545	COG1476	TRANSCRIPTIONal
AS858_RS12555	COG1131	(ABC) transporter
AS858_RS12590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AS858_RS12590	COG0646	methionine synthase
AS858_RS12595	COG0626	cystathionine gamma-synthase activity
AS858_RS12600	COG0626	cystathionine gamma-synthase activity
AS858_RS12605	COG1475	DNA binding
AS858_RS12610	COG0668	transmembrane transport
AS858_RS12615	COG4481	Protein conserved in bacteria
AS858_RS12620	COG0012	GTP binding
AS858_RS12650	COG4974	Belongs to the 'phage' integrase family
AS858_RS12710	COG3634	alkyl hydroperoxide reductase activity
AS858_RS12725	COG1823	symporter activity
AS858_RS12755	COG2233	PERMEase
AS858_RS12790	COG3759	membrane
AS858_RS12960	COG0523	cobalamin synthesis protein
AS858_RS12970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS858_RS12980	COG5609	conserved protein (DUF2294)
AS858_RS12995	COG1647	Serine aminopeptidase, S33
AS858_RS13005	COG0733	neurotransmitter:sodium symporter activity
AS858_RS13010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS858_RS13015	COG0626	cystathionine gamma-synthase activity
AS858_RS13025	COG2011	ABC-type metal ion transport system permease component
AS858_RS13030	COG1464	Belongs to the NlpA lipoprotein family
AS858_RS13065	COG0583	DNA-binding transcription factor activity
AS858_RS13070	COG0070	glutamate synthase
AS858_RS13070	COG0067	glutamate synthase
AS858_RS13070	COG0069	glutamate synthase activity
AS858_RS13075	COG0493	'glutamate synthase
AS858_RS13085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS858_RS13085	COG1263	PTS System
AS858_RS13090	COG0366	Alpha amylase catalytic
AS858_RS13095	COG2188	Transcriptional regulator
AS858_RS13115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS858_RS13150	COG1982	Orn Lys Arg decarboxylase major
AS858_RS13160	COG3870	Protein conserved in bacteria
AS858_RS13170	COG0470	DNA polymerase III
AS858_RS13175	COG1774	PSP1 C-terminal conserved region
AS858_RS13185	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AS858_RS13195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AS858_RS13210	COG0084	hydrolase, TatD family'
AS858_RS13215	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS858_RS13225	COG4466	Protein conserved in bacteria
AS858_RS13235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS858_RS13240	COG0251	oxidation-reduction process
AS858_RS13285	COG2244	polysaccharide biosynthetic process
AS858_RS13290	COG3956	TIGRFAM MazG family protein
AS858_RS13295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AS858_RS13305	COG1098	S1 RNA binding domain
AS858_RS13320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS858_RS13345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS858_RS13440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS858_RS13455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS858_RS13465	COG3880	PFAM UvrB UvrC protein
AS858_RS13485	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AS858_RS13490	COG4956	integral membrane protein (PIN domain superfamily)
AS858_RS13510	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AS858_RS13560	COG2813	Specifically methylates the guanine in position
AS858_RS13600	COG1473	amidohydrolase
AS858_RS13630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AS858_RS13635	COG1428	Deoxynucleoside kinase
AS858_RS13640	COG1428	Deoxynucleoside kinase
AS858_RS13650	COG0561	phosphatase activity
AS858_RS13690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS858_RS13795	COG0095	Lipoate-protein ligase
AS858_RS13800	COG0083	homoserine kinase activity
AS858_RS13820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS858_RS13905	COG0667	Aldo Keto reductase
AS858_RS13910	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS858_RS13920	COG1078	dGTPase activity
AS858_RS13955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS858_RS13960	COG4139	cobalamin transport
AS858_RS14000	COG2826	transposase and inactivated derivatives, IS30 family
AS858_RS14030	COG1674	ftsk spoiiie
AS858_RS14035	COG0433	COG0433 Predicted ATPase
AS858_RS14055	COG2946	Replication initiation factor
AS858_RS14090	COG4974	Belongs to the 'phage' integrase family
AS858_RS14135	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS858_RS14140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS858_RS14145	COG1121	(ABC) transporter
AS858_RS14150	COG1321	iron dependent repressor
AS858_RS14160	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AS858_RS14170	COG1682	transport, permease protein
AS858_RS14175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS858_RS14180	COG1216	Glycosyl transferase, family 2
AS858_RS14185	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AS858_RS14190	COG1686	Belongs to the peptidase S11 family
AS858_RS14195	COG1132	(ABC) transporter
AS858_RS14200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS858_RS14210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS858_RS14215	COG1120	ATPase activity
AS858_RS14220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS858_RS14225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS858_RS14230	COG2376	Dihydroxyacetone kinase
AS858_RS14240	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AS858_RS14250	COG3949	Membrane
AS858_RS14275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS858_RS14290	COG1136	(ABC) transporter
AS858_RS14295	COG0577	efflux transmembrane transporter activity
AS858_RS14300	COG1392	Phosphate transport regulator
AS858_RS14305	COG0306	phosphate transporter
AS858_RS14310	COG1388	LysM domain
AS858_RS14310	COG3942	CHAP domain
AS858_RS14320	COG4977	sequence-specific DNA binding
AS858_RS14320	COG1917	Cupin 2, conserved barrel domain protein
AS858_RS14350	COG0583	DNA-binding transcription factor activity
AS858_RS14360	COG2814	Major facilitator Superfamily
AS858_RS14365	COG2839	Protein conserved in bacteria
AS858_RS14395	COG1611	Belongs to the LOG family
AS858_RS14415	COG4988	ABC transporter
AS858_RS14420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AS858_RS14430	COG0523	cobalamin synthesis protein
AS858_RS14435	COG4989	oxidoreductase activity
AS858_RS14445	COG0471	metal ion transport
AS858_RS14450	COG0415	Belongs to the DNA photolyase family
AS858_RS14480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS858_RS14485	COG1349	DNA-binding transcription factor activity
AS858_RS14490	COG1105	Belongs to the carbohydrate kinase PfkB family
AS858_RS14495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS858_RS14495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS858_RS14495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS858_RS14505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AS858_RS14510	COG1253	flavin adenine dinucleotide binding
AS858_RS14515	COG0656	L-ascorbic acid biosynthetic process
AS858_RS14520	COG0463	Glycosyl transferase, family 2
AS858_RS14555	COG0720	synthase
AS858_RS14565	COG0512	Glutamine amidotransferase of anthranilate synthase
AS858_RS14565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS858_RS14570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS858_RS14605	COG0488	(ABC) transporter
AS858_RS14610	COG0514	ATP-dependent DNA helicase (RecQ)
AS858_RS14615	COG0517	IMP dehydrogenase activity
AS858_RS14615	COG1125	glycine betaine transport
AS858_RS14620	COG1174	glycine betaine transport
AS858_RS14645	COG3104	oligopeptide transport
AS858_RS14665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS858_RS14670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS858_RS14685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS858_RS14690	COG4605	iron ion homeostasis
AS858_RS14695	COG4604	ABC transporter, ATP-binding protein
AS858_RS14700	COG4607	ABC-type enterochelin transport system periplasmic component
AS858_RS14755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS858_RS14760	COG1739	Uncharacterized protein family UPF0029
AS858_RS14770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AS858_RS14775	COG1040	competence protein
AS858_RS14805	COG3942	CHAP domain
AS858_RS14805	COG1388	LysM domain
AS858_RS14865	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS858_RS14930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS858_RS14935	COG1647	Serine aminopeptidase, S33
AS858_RS14940	COG0557	exoribonuclease II activity
AS858_RS15015	COG1278	Cold shock
AS858_RS15055	COG0406	alpha-ribazole phosphatase activity
AS858_RS15060	COG1279	arginine transmembrane transporter activity
AS858_RS15085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS858_RS15090	COG1393	Belongs to the ArsC family
AS858_RS15105	COG3878	Protein conserved in bacteria
AS858_RS15115	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS858_RS15130	COG2011	ABC-type metal ion transport system permease component
AS858_RS15135	COG1464	Belongs to the NlpA lipoprotein family
AS858_RS15140	COG0582	viral genome integration into host DNA
AS858_RS15235	COG0396	ATPase activity
AS858_RS15240	COG0719	Fe-S assembly protein
AS858_RS15250	COG0822	iron-sulfur transferase activity
AS858_RS15270	COG1253	flavin adenine dinucleotide binding
AS858_RS15285	COG1801	Protein of unknown function DUF72
AS858_RS15290	COG0730	response to heat
AS858_RS15305	COG4470	Protein conserved in bacteria
AS858_RS15315	COG2445	Protein of unknown function DUF86
AS858_RS15345	COG1696	Membrane protein involved in D-alanine export
AS858_RS15355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS858_RS15360	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AS858_RS15365	COG4837	Protein of unknown function (DUF1462)
AS858_RS15370	COG1252	NADH dehydrogenase
AS858_RS15380	COG0316	Belongs to the HesB IscA family
AS858_RS15390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS858_RS15395	COG2056	Na+-H+ antiporter family
AS858_RS15400	COG2050	protein possibly involved in aromatic compounds catabolism
AS858_RS15455	COG1098	S1 RNA binding domain
AS858_RS15460	COG1902	pentaerythritol trinitrate reductase activity
AS858_RS15480	COG0584	glycerophosphoryl diester phosphodiesterase
AS858_RS15500	COG0398	Pfam SNARE associated Golgi protein
AS858_RS15540	COG0561	phosphatase activity
AS858_RS15565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS858_RS15580	COG1881	PFAM PEBP family protein