locus-tag	class	description
EP20_RS00015	COG2501	S4 domain
EP20_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EP20_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EP20_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EP20_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
EP20_RS00110	COG4863	YycH protein
EP20_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EP20_RS00125	COG0737	Belongs to the 5'-nucleotidase family
EP20_RS00155	COG0584	glycerophosphoryl diester phosphodiesterase
EP20_RS00160	COG2030	dehydratase
EP20_RS00230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EP20_RS00235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EP20_RS00275	COG0730	response to heat
EP20_RS00280	COG1937	Protein conserved in bacteria
EP20_RS00285	COG2210	Belongs to the sulfur carrier protein TusA family
EP20_RS00290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EP20_RS00325	COG0655	NAD(P)H dehydrogenase (quinone) activity
EP20_RS00340	COG0583	DNA-binding transcription factor activity
EP20_RS00360	COG0823	Involved in the tonB-independent uptake of proteins
EP20_RS00390	COG1473	amidohydrolase
EP20_RS00400	COG1283	sodium-dependent phosphate transmembrane transporter activity
EP20_RS00405	COG4716	Myosin-crossreactive antigen
EP20_RS00410	COG0697	spore germination
EP20_RS00425	COG1620	l-lactate permease
EP20_RS00440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EP20_RS00445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EP20_RS00450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EP20_RS00460	COG2423	ornithine cyclodeaminase activity
EP20_RS00465	COG4264	IucA IucC family
EP20_RS00470	COG2814	Major facilitator Superfamily
EP20_RS00475	COG4264	IucA IucC family
EP20_RS00480	COG4264	IucA IucC family
EP20_RS00490	COG0019	diaminopimelate decarboxylase activity
EP20_RS00495	COG1475	DNA binding
EP20_RS00525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EP20_RS00530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EP20_RS00535	COG0438	transferase activity, transferring glycosyl groups
EP20_RS00570	COG0813	purine-nucleoside phosphorylase activity
EP20_RS00575	COG2814	Major facilitator Superfamily
EP20_RS00595	COG3639	organic phosphonate transmembrane transporter activity
EP20_RS00615	COG0737	Belongs to the 5'-nucleotidase family
EP20_RS00645	COG1012	belongs to the aldehyde dehydrogenase family
EP20_RS00645	COG1454	alcohol dehydrogenase
EP20_RS00670	COG1086	Polysaccharide biosynthesis protein
EP20_RS00680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EP20_RS00710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EP20_RS00720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EP20_RS00725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EP20_RS00735	COG2832	Protein of unknown function (DUF454)
EP20_RS00770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EP20_RS00775	COG1960	acyl-CoA dehydrogenase activity
EP20_RS00780	COG5609	conserved protein (DUF2294)
EP20_RS00830	COG1114	Component of the transport system for branched-chain amino acids
EP20_RS00835	COG1335	isochorismatase
EP20_RS00840	COG3961	Belongs to the TPP enzyme family
EP20_RS00870	COG1737	Transcriptional regulator
EP20_RS00905	COG0601	transmembrane transport
EP20_RS00910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EP20_RS00920	COG0405	Gamma-glutamyltransferase
EP20_RS00940	COG3842	ATPase activity
EP20_RS00950	COG1175	transmembrane transport
EP20_RS00955	COG3833	ABC-type maltose transport systems, permease component
EP20_RS00960	COG0673	inositol 2-dehydrogenase activity
EP20_RS00965	COG0673	inositol 2-dehydrogenase activity
EP20_RS00975	COG1755	Isoprenylcysteine carboxyl methyltransferase
EP20_RS01065	COG1755	Isoprenylcysteine carboxyl methyltransferase
EP20_RS01120	COG0183	Belongs to the thiolase family
EP20_RS01130	COG1960	acyl-CoA dehydrogenase activity
EP20_RS01135	COG0318	PFAM AMP-dependent synthetase and ligase
EP20_RS01150	COG0747	negative chemotaxis
EP20_RS01155	COG3189	MarR family transcriptional regulator
EP20_RS01185	COG2190	(PTS) system
EP20_RS01185	COG1263	PTS System
EP20_RS01185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EP20_RS01190	COG1957	nucleoside hydrolase
EP20_RS01210	COG3414	Phosphotransferase system galactitol-specific IIB component
EP20_RS01215	COG3775	system Galactitol-specific IIC component
EP20_RS01220	COG1063	alcohol dehydrogenase
EP20_RS01230	COG1063	alcohol dehydrogenase
EP20_RS01240	COG1063	alcohol dehydrogenase
EP20_RS01245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EP20_RS01250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EP20_RS01260	COG1063	alcohol dehydrogenase
EP20_RS01265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EP20_RS01300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EP20_RS01305	COG2190	(PTS) system
EP20_RS01305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EP20_RS01305	COG1263	PTS System
EP20_RS01310	COG2723	6-phospho-beta-galactosidase activity
EP20_RS01320	COG2226	methyltransferase
EP20_RS01380	COG1131	(ABC) transporter
EP20_RS01410	COG3942	CHAP domain
EP20_RS01410	COG1388	LysM domain
EP20_RS01555	COG1114	Component of the transport system for branched-chain amino acids
EP20_RS01560	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EP20_RS01570	COG0577	efflux transmembrane transporter activity
EP20_RS01595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EP20_RS01600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EP20_RS01625	COG3314	Sporulation integral membrane protein YlbJ
EP20_RS01650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EP20_RS01680	COG3037	sugar-specific permease SgaT UlaA
EP20_RS01690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EP20_RS01695	COG3711	transcriptional antiterminator
EP20_RS01715	COG2271	Major facilitator Superfamily
EP20_RS01720	COG0346	lactoylglutathione lyase activity
EP20_RS01725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EP20_RS01730	COG0431	NADPH-dependent FMN reductase
EP20_RS01745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EP20_RS01750	COG2822	iron ion transport
EP20_RS01760	COG0672	)-iron permease
EP20_RS01765	COG0805	protein transport
EP20_RS01770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EP20_RS01780	COG1476	TRANSCRIPTIONal
EP20_RS01790	COG1131	(ABC) transporter
EP20_RS01825	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EP20_RS01825	COG0646	methionine synthase
EP20_RS01830	COG0626	cystathionine gamma-synthase activity
EP20_RS01835	COG0626	cystathionine gamma-synthase activity
EP20_RS01840	COG1475	DNA binding
EP20_RS01845	COG0668	transmembrane transport
EP20_RS01850	COG4481	Protein conserved in bacteria
EP20_RS01855	COG0012	GTP binding
EP20_RS01885	COG4974	Belongs to the 'phage' integrase family
EP20_RS01945	COG3634	alkyl hydroperoxide reductase activity
EP20_RS01960	COG1823	symporter activity
EP20_RS01990	COG2233	PERMEase
EP20_RS02025	COG3759	membrane
EP20_RS02195	COG0523	cobalamin synthesis protein
EP20_RS02205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EP20_RS02215	COG5609	conserved protein (DUF2294)
EP20_RS02230	COG1647	Serine aminopeptidase, S33
EP20_RS02240	COG0733	neurotransmitter:sodium symporter activity
EP20_RS02245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EP20_RS02250	COG0626	cystathionine gamma-synthase activity
EP20_RS02260	COG2011	ABC-type metal ion transport system permease component
EP20_RS02265	COG1464	Belongs to the NlpA lipoprotein family
EP20_RS02300	COG0583	DNA-binding transcription factor activity
EP20_RS02305	COG0070	glutamate synthase
EP20_RS02305	COG0069	glutamate synthase activity
EP20_RS02305	COG0067	glutamate synthase
EP20_RS02310	COG0493	'glutamate synthase
EP20_RS02320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EP20_RS02320	COG1263	PTS System
EP20_RS02325	COG0366	Alpha amylase catalytic
EP20_RS02330	COG2188	Transcriptional regulator
EP20_RS02345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EP20_RS02380	COG1982	Orn Lys Arg decarboxylase major
EP20_RS02390	COG3870	Protein conserved in bacteria
EP20_RS02400	COG0470	DNA polymerase III
EP20_RS02405	COG1774	PSP1 C-terminal conserved region
EP20_RS02415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EP20_RS02425	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EP20_RS02440	COG0084	hydrolase, TatD family'
EP20_RS02445	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EP20_RS02455	COG4466	Protein conserved in bacteria
EP20_RS02465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EP20_RS02470	COG0251	oxidation-reduction process
EP20_RS02515	COG2244	polysaccharide biosynthetic process
EP20_RS02520	COG3956	TIGRFAM MazG family protein
EP20_RS02525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EP20_RS02535	COG1098	S1 RNA binding domain
EP20_RS02550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EP20_RS02575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EP20_RS02670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EP20_RS02685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EP20_RS02695	COG3880	PFAM UvrB UvrC protein
EP20_RS02715	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EP20_RS02720	COG4956	integral membrane protein (PIN domain superfamily)
EP20_RS02740	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EP20_RS02790	COG2813	Specifically methylates the guanine in position
EP20_RS02830	COG1473	amidohydrolase
EP20_RS02860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EP20_RS02865	COG1428	Deoxynucleoside kinase
EP20_RS02870	COG1428	Deoxynucleoside kinase
EP20_RS02880	COG0561	phosphatase activity
EP20_RS02920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EP20_RS02935	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EP20_RS03025	COG0095	Lipoate-protein ligase
EP20_RS03030	COG0083	homoserine kinase activity
EP20_RS03050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EP20_RS03135	COG0667	Aldo Keto reductase
EP20_RS03140	COG0655	NAD(P)H dehydrogenase (quinone) activity
EP20_RS03150	COG1078	dGTPase activity
EP20_RS03185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EP20_RS03190	COG4139	cobalamin transport
EP20_RS03240	COG4974	Belongs to the 'phage' integrase family
EP20_RS03285	COG0803	Belongs to the bacterial solute-binding protein 9 family
EP20_RS03290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EP20_RS03295	COG1121	(ABC) transporter
EP20_RS03300	COG1321	iron dependent repressor
EP20_RS03310	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EP20_RS03320	COG1682	transport, permease protein
EP20_RS03325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EP20_RS03330	COG1216	Glycosyl transferase, family 2
EP20_RS03335	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EP20_RS03340	COG1686	Belongs to the peptidase S11 family
EP20_RS03345	COG1132	(ABC) transporter
EP20_RS03350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EP20_RS03360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EP20_RS03365	COG1120	ATPase activity
EP20_RS03370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EP20_RS03375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EP20_RS03380	COG2376	Dihydroxyacetone kinase
EP20_RS03390	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EP20_RS03400	COG3949	Membrane
EP20_RS03425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EP20_RS03440	COG1136	(ABC) transporter
EP20_RS03445	COG0577	efflux transmembrane transporter activity
EP20_RS03450	COG1392	Phosphate transport regulator
EP20_RS03455	COG0306	phosphate transporter
EP20_RS03460	COG3942	CHAP domain
EP20_RS03460	COG1388	LysM domain
EP20_RS03470	COG4977	sequence-specific DNA binding
EP20_RS03470	COG1917	Cupin 2, conserved barrel domain protein
EP20_RS03500	COG0583	DNA-binding transcription factor activity
EP20_RS03510	COG2814	Major facilitator Superfamily
EP20_RS03515	COG2839	Protein conserved in bacteria
EP20_RS03545	COG1611	Belongs to the LOG family
EP20_RS03565	COG4988	ABC transporter
EP20_RS03570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EP20_RS03580	COG0523	cobalamin synthesis protein
EP20_RS03585	COG4989	oxidoreductase activity
EP20_RS03595	COG0471	metal ion transport
EP20_RS03600	COG0415	Belongs to the DNA photolyase family
EP20_RS03630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EP20_RS03635	COG1349	DNA-binding transcription factor activity
EP20_RS03640	COG1105	Belongs to the carbohydrate kinase PfkB family
EP20_RS03645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EP20_RS03645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EP20_RS03645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EP20_RS03655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EP20_RS03660	COG1253	flavin adenine dinucleotide binding
EP20_RS03665	COG0656	L-ascorbic acid biosynthetic process
EP20_RS03670	COG0463	Glycosyl transferase, family 2
EP20_RS03705	COG0720	synthase
EP20_RS03715	COG0512	Glutamine amidotransferase of anthranilate synthase
EP20_RS03715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EP20_RS03720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EP20_RS03755	COG0488	(ABC) transporter
EP20_RS03760	COG0514	ATP-dependent DNA helicase (RecQ)
EP20_RS03765	COG1125	glycine betaine transport
EP20_RS03765	COG0517	IMP dehydrogenase activity
EP20_RS03770	COG1174	glycine betaine transport
EP20_RS03795	COG3104	oligopeptide transport
EP20_RS03815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EP20_RS03820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EP20_RS03835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EP20_RS03840	COG4605	iron ion homeostasis
EP20_RS03845	COG4604	ABC transporter, ATP-binding protein
EP20_RS03850	COG4607	ABC-type enterochelin transport system periplasmic component
EP20_RS03905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EP20_RS03910	COG1739	Uncharacterized protein family UPF0029
EP20_RS03920	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EP20_RS03925	COG1040	competence protein
EP20_RS03955	COG3942	CHAP domain
EP20_RS03955	COG1388	LysM domain
EP20_RS04015	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EP20_RS04085	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EP20_RS04090	COG1647	Serine aminopeptidase, S33
EP20_RS04095	COG0557	exoribonuclease II activity
EP20_RS04165	COG1278	Cold shock
EP20_RS04205	COG0406	alpha-ribazole phosphatase activity
EP20_RS04210	COG1279	arginine transmembrane transporter activity
EP20_RS04235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EP20_RS04240	COG1393	Belongs to the ArsC family
EP20_RS04255	COG3878	Protein conserved in bacteria
EP20_RS04265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EP20_RS04280	COG2011	ABC-type metal ion transport system permease component
EP20_RS04285	COG1464	Belongs to the NlpA lipoprotein family
EP20_RS04290	COG0582	viral genome integration into host DNA
EP20_RS04390	COG0396	ATPase activity
EP20_RS04395	COG0719	Fe-S assembly protein
EP20_RS04405	COG0822	iron-sulfur transferase activity
EP20_RS04425	COG1253	flavin adenine dinucleotide binding
EP20_RS04440	COG1801	Protein of unknown function DUF72
EP20_RS04445	COG0730	response to heat
EP20_RS04460	COG4470	Protein conserved in bacteria
EP20_RS04470	COG2445	Protein of unknown function DUF86
EP20_RS04500	COG1696	Membrane protein involved in D-alanine export
EP20_RS04510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EP20_RS04515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EP20_RS04520	COG4837	Protein of unknown function (DUF1462)
EP20_RS04525	COG1252	NADH dehydrogenase
EP20_RS04535	COG0316	Belongs to the HesB IscA family
EP20_RS04545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EP20_RS04550	COG2056	Na+-H+ antiporter family
EP20_RS04555	COG2050	protein possibly involved in aromatic compounds catabolism
EP20_RS04610	COG1098	S1 RNA binding domain
EP20_RS04615	COG1902	pentaerythritol trinitrate reductase activity
EP20_RS04635	COG0584	glycerophosphoryl diester phosphodiesterase
EP20_RS04655	COG0398	Pfam SNARE associated Golgi protein
EP20_RS04695	COG0561	phosphatase activity
EP20_RS04720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EP20_RS04735	COG1881	PFAM PEBP family protein
EP20_RS04765	COG0601	transmembrane transport
EP20_RS04770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EP20_RS04775	COG0444	Belongs to the ABC transporter superfamily
EP20_RS04780	COG4608	Belongs to the ABC transporter superfamily
EP20_RS04785	COG4166	transmembrane transport
EP20_RS04790	COG0747	negative chemotaxis
EP20_RS04795	COG0444	Belongs to the ABC transporter superfamily
EP20_RS04800	COG4608	Belongs to the ABC transporter superfamily
EP20_RS04805	COG0601	transmembrane transport
EP20_RS04810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EP20_RS04835	COG1164	Oligoendopeptidase f
EP20_RS04845	COG2346	COG2346, Truncated hemoglobins
EP20_RS04860	COG2357	RelA SpoT domain protein
EP20_RS04870	COG0564	pseudouridine synthase activity
EP20_RS04875	COG2239	Acts as a magnesium transporter
EP20_RS04880	COG0475	glutathione-regulated potassium exporter activity
EP20_RS04880	COG0569	domain protein
EP20_RS04890	COG0628	permease
EP20_RS04895	COG1115	amino acid carrier protein
EP20_RS04935	COG0861	Integral membrane protein TerC family
EP20_RS04945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EP20_RS04950	COG0737	Belongs to the 5'-nucleotidase family
EP20_RS04980	COG4873	Protein conserved in bacteria
EP20_RS05035	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EP20_RS05045	COG2314	TM2 domain
EP20_RS05050	COG0456	acetyltransferase
EP20_RS05055	COG1575	Belongs to the MenA family. Type 1 subfamily
EP20_RS05060	COG1169	isochorismate synthase
EP20_RS05070	COG2267	carboxylic ester hydrolase activity
EP20_RS05095	COG0436	Aminotransferase
EP20_RS05100	COG3594	Acyltransferase
EP20_RS05130	COG1316	TRANSCRIPTIONal
EP20_RS05135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EP20_RS05175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EP20_RS05190	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EP20_RS05230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EP20_RS05235	COG4172	Belongs to the ABC transporter superfamily
EP20_RS05240	COG4721	ABC-type cobalt transport system, permease component
EP20_RS05260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EP20_RS05285	COG1271	oxidase subunit
EP20_RS05290	COG1294	oxidase, subunit
EP20_RS05295	COG0569	domain protein
EP20_RS05365	COG1176	ABC-type spermidine putrescine transport system, permease component I
EP20_RS05370	COG1177	transmembrane transport
EP20_RS05375	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EP20_RS05400	COG0483	inositol monophosphate 1-phosphatase activity
EP20_RS05410	COG1217	gtp-binding protein TYPA
EP20_RS05420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EP20_RS05430	COG0772	Belongs to the SEDS family
EP20_RS05465	COG3679	Belongs to the UPF0342 family
EP20_RS05485	COG0742	ribosomal rna small subunit methyltransferase
EP20_RS05545	COG4509	Sortase family
EP20_RS05560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EP20_RS05590	COG1796	DNA polymerase
EP20_RS05590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EP20_RS05615	COG2009	succinate dehydrogenase
EP20_RS05620	COG1053	succinate dehydrogenase
EP20_RS05625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EP20_RS05745	COG1288	antiporter activity
EP20_RS05780	COG1011	Hydrolase
EP20_RS05805	COG4839	cell division protein FtsL
EP20_RS05810	COG0768	penicillin binding
EP20_RS05825	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EP20_RS05830	COG0849	cell division
EP20_RS05845	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EP20_RS05855	COG0762	integral membrane protein
EP20_RS05860	COG2302	S4 RNA-binding domain
EP20_RS05865	COG3599	regulation of cell shape
EP20_RS05875	COG2514	catechol 2,3-dioxygenase activity
EP20_RS05890	COG0564	pseudouridine synthase activity
EP20_RS05900	COG2233	PERMEase
EP20_RS05945	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EP20_RS05960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EP20_RS05965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EP20_RS05975	COG2314	TM2 domain
EP20_RS05990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EP20_RS05990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EP20_RS06000	COG0631	protein serine/threonine phosphatase activity
EP20_RS06015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EP20_RS06030	COG1302	Protein conserved in bacteria
EP20_RS06040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EP20_RS06080	COG1196	nuclear chromosome segregation
EP20_RS06085	COG0552	protein localization to endoplasmic reticulum
EP20_RS06095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EP20_RS06160	COG0758	DNA mediated transformation
EP20_RS06255	COG0195	Participates in both transcription termination and antitermination
EP20_RS06260	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EP20_RS06285	COG0196	riboflavin kinase activity
EP20_RS06310	COG2188	Transcriptional regulator
EP20_RS06315	COG0612	Peptidase, M16
EP20_RS06320	COG0612	Peptidase, M16
EP20_RS06325	COG0300	oxidoreductase activity
EP20_RS06345	COG1546	Belongs to the CinA family
EP20_RS06345	COG1058	Belongs to the CinA family
EP20_RS06365	COG1692	metallophosphoesterase
EP20_RS06370	COG0674	pyruvate-flavodoxin oxidoreductase activity
EP20_RS06370	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EP20_RS06375	COG1013	pyruvate-flavodoxin oxidoreductase activity
EP20_RS06410	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EP20_RS06415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EP20_RS06440	COG1923	regulation of RNA biosynthetic process
EP20_RS06450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EP20_RS06455	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EP20_RS06460	COG0789	Transcriptional regulator
EP20_RS06580	COG1131	(ABC) transporter
EP20_RS06595	COG2197	response regulator
EP20_RS06605	COG1525	nuclease
EP20_RS06620	COG0527	aspartate kinase activity
EP20_RS06625	COG0460	homoserine dehydrogenase
EP20_RS06630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EP20_RS06655	COG0833	amino acid
EP20_RS06685	COG2340	Cysteine-rich secretory protein family
EP20_RS06720	COG4846	Membrane protein involved in cytochrome C biogenesis
EP20_RS06740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EP20_RS06750	COG0824	Thioesterase
EP20_RS06770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EP20_RS06780	COG1115	amino acid carrier protein
EP20_RS06795	COG0628	permease
EP20_RS06800	COG0392	lysyltransferase activity
EP20_RS06800	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EP20_RS06820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EP20_RS06830	COG1363	Peptidase, m42
EP20_RS06835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EP20_RS06840	COG0512	Glutamine amidotransferase of anthranilate synthase
EP20_RS06880	COG0561	phosphatase activity
EP20_RS06925	COG0704	Plays a role in the regulation of phosphate uptake
EP20_RS06935	COG0581	inorganic phosphate transmembrane transporter activity
EP20_RS06940	COG0573	inorganic phosphate transmembrane transporter activity
EP20_RS06965	COG0488	(ABC) transporter
EP20_RS06970	COG0527	aspartate kinase activity
EP20_RS06975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EP20_RS07060	COG4548	von Willebrand factor, type A
EP20_RS07065	COG0714	Associated with various cellular activities
EP20_RS07115	COG0671	phosphoesterase, PA-phosphatase related
EP20_RS07195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EP20_RS07225	COG0531	amino acid
EP20_RS07240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EP20_RS07245	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EP20_RS07265	COG0116	Belongs to the methyltransferase superfamily
EP20_RS07295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EP20_RS07295	COG4499	WXG100 protein secretion system (Wss), protein YukC
EP20_RS07305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EP20_RS07310	COG3935	DnaD domain protein
EP20_RS07335	COG0438	transferase activity, transferring glycosyl groups
EP20_RS07340	COG1694	Mazg nucleotide pyrophosphohydrolase
EP20_RS07345	COG2738	Putative neutral zinc metallopeptidase
EP20_RS07350	COG4347	Protein of unknown function (DUF1405)
EP20_RS07390	COG0142	geranyltranstransferase activity
EP20_RS07455	COG0492	ferredoxin-NADP+ reductase activity
EP20_RS07470	COG0514	ATP-dependent DNA helicase (RecQ)
EP20_RS07480	COG1141	Ferredoxin
EP20_RS07530	COG1388	LysM domain
EP20_RS07530	COG0860	N-Acetylmuramoyl-L-alanine amidase
EP20_RS07580	COG5280	Phage tail tape measure protein TP901
EP20_RS07580	COG3953	SLT domain
EP20_RS07835	COG0582	viral genome integration into host DNA
EP20_RS07850	COG5002	protein histidine kinase activity
EP20_RS07855	COG0745	RESPONSE REGULATOR receiver
EP20_RS07860	COG1187	pseudouridine synthase activity
EP20_RS07885	COG0735	belongs to the Fur family
EP20_RS07890	COG0494	nUDIX hydrolase
EP20_RS07895	COG0667	Aldo Keto reductase
EP20_RS07905	COG4221	oxidoreductase activity
EP20_RS07920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EP20_RS07930	COG0366	Alpha amylase catalytic
EP20_RS07935	COG1609	Transcriptional regulator
EP20_RS07955	COG2195	Cleaves the N-terminal amino acid of tripeptides
EP20_RS07965	COG4129	membrane
EP20_RS07975	COG0508	dehydrogenase complex catalyzes the overall conversion of
EP20_RS07980	COG0022	dehydrogenase e1 component
EP20_RS07985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EP20_RS07990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EP20_RS07995	COG0497	DNA recombination
EP20_RS08025	COG1302	Protein conserved in bacteria
EP20_RS08030	COG0439	Biotin carboxylase
EP20_RS08035	COG0511	ligase activity, forming carbon-carbon bonds
EP20_RS08045	COG0006	proline dipeptidase activity
EP20_RS08060	COG0095	Lipoate-protein ligase
EP20_RS08065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EP20_RS08110	COG4537	Required for transformation and DNA binding
EP20_RS08115	COG1459	type II secretion system
EP20_RS08120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EP20_RS08125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EP20_RS08130	COG0011	TIGRFAM Protein of
EP20_RS08135	COG1940	carbohydrate kinase activity
EP20_RS08140	COG4483	Protein conserved in bacteria
EP20_RS08150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EP20_RS08160	COG0768	penicillin binding
EP20_RS08175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EP20_RS08180	COG1121	(ABC) transporter
EP20_RS08190	COG0513	Belongs to the DEAD box helicase family
EP20_RS08200	COG2384	SAM-dependent methyltransferase
EP20_RS08220	COG0517	IMP dehydrogenase activity
EP20_RS08240	COG0295	cytidine deaminase activity
EP20_RS08255	COG1702	phosphate starvation-inducible protein PhoH
EP20_RS08270	COG1030	water channel activity
EP20_RS08280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EP20_RS08285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EP20_RS08315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EP20_RS08335	COG1466	dna polymerase III delta subunit
EP20_RS08345	COG2131	deaminase
EP20_RS08355	COG2226	methyltransferase
EP20_RS08360	COG0799	negative regulation of ribosome biogenesis
EP20_RS08365	COG1713	HD superfamily hydrolase involved in NAD metabolism
EP20_RS08375	COG1534	Rna-binding protein
EP20_RS08385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EP20_RS08390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EP20_RS08415	COG3177	Filamentation induced by cAMP protein fic
EP20_RS08420	COG1914	H( )-stimulated, divalent metal cation uptake system
EP20_RS08430	COG0439	Biotin carboxylase
EP20_RS08435	COG0511	ligase activity, forming carbon-carbon bonds
EP20_RS08440	COG1984	allophanate hydrolase subunit 2
EP20_RS08445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EP20_RS08460	COG0826	peptidase U32
EP20_RS08465	COG0826	peptidase U32
EP20_RS08495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EP20_RS08510	COG1104	cysteine desulfurase activity
EP20_RS08515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EP20_RS08530	COG1959	2 iron, 2 sulfur cluster binding
EP20_RS08535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EP20_RS08540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EP20_RS08580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EP20_RS08580	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EP20_RS08585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EP20_RS08585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EP20_RS08590	COG1862	Preprotein translocase
EP20_RS08630	COG2868	ribosomal protein
EP20_RS08670	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EP20_RS08680	COG0285	dihydrofolate synthase activity
EP20_RS08690	COG2818	Glycosylase
EP20_RS08725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EP20_RS08760	COG4112	unkown
EP20_RS08785	COG0833	amino acid
EP20_RS08800	COG1484	DNA-dependent DNA replication
EP20_RS08830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EP20_RS08830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EP20_RS08840	COG5002	protein histidine kinase activity
EP20_RS08845	COG0745	RESPONSE REGULATOR receiver
EP20_RS08860	COG0372	Belongs to the citrate synthase family
EP20_RS08865	COG1113	amino acid transport
EP20_RS08900	COG0281	malic enzyme
EP20_RS08910	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EP20_RS08915	COG4109	DRTGG domain
EP20_RS08955	COG0827	DNA restriction-modification system
EP20_RS08975	COG1104	cysteine desulfurase activity
EP20_RS08990	COG1956	GAF domain-containing protein
EP20_RS09005	COG0584	glycerophosphoryl diester phosphodiesterase
EP20_RS09010	COG1764	response to oxidative stress
EP20_RS09015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EP20_RS09020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EP20_RS09035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EP20_RS09035	COG1263	PTS System
EP20_RS09040	COG0204	Acyl-transferase
EP20_RS09045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EP20_RS09080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EP20_RS09085	COG0454	-acetyltransferase
EP20_RS09105	COG1605	Chorismate mutase
EP20_RS09105	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EP20_RS09130	COG1674	ftsk spoiiie
EP20_RS09135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EP20_RS09145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EP20_RS09150	COG1363	Peptidase, m42
EP20_RS09160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EP20_RS09170	COG0510	thiamine kinase activity
EP20_RS09190	COG1187	pseudouridine synthase activity
EP20_RS09195	COG2244	polysaccharide biosynthetic process
EP20_RS09200	COG2081	HI0933 family
EP20_RS09220	COG2814	Major facilitator Superfamily
EP20_RS09225	COG1242	4 iron, 4 sulfur cluster binding
EP20_RS09230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EP20_RS09250	COG2267	carboxylic ester hydrolase activity
EP20_RS09280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EP20_RS09280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EP20_RS09305	COG4193	domain, Protein
EP20_RS09305	COG5632	N-Acetylmuramoyl-L-alanine amidase
EP20_RS09305	COG3266	domain, Protein
EP20_RS09335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EP20_RS09365	COG0656	L-ascorbic acid biosynthetic process
EP20_RS09390	COG1506	peptidase
EP20_RS09535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EP20_RS09565	COG1131	(ABC) transporter
EP20_RS09570	COG0537	adenosine 5'-monophosphoramidase activity
EP20_RS09600	COG0420	3'-5' exonuclease activity
EP20_RS09625	COG2197	response regulator
EP20_RS09630	COG2203	Gaf domain
EP20_RS09630	COG4585	Histidine kinase
EP20_RS09635	COG0564	pseudouridine synthase activity
EP20_RS09670	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EP20_RS09675	COG1126	abc transporter atp-binding protein
EP20_RS09680	COG0765	amino acid transport
EP20_RS09850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EP20_RS09855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EP20_RS09865	COG4129	membrane
EP20_RS09890	COG1988	membrane-bound metal-dependent
EP20_RS09905	COG1134	teichoic acid transport
EP20_RS09905	COG1388	LysM domain
EP20_RS09935	COG0535	radical SAM domain protein
EP20_RS09940	COG1607	acyl-coa hydrolase
EP20_RS09945	COG2309	aminopeptidase activity
EP20_RS09965	COG1295	ribonuclease BN
EP20_RS09970	COG2197	response regulator
EP20_RS10085	COG4851	CamS sex pheromone cAM373 precursor
EP20_RS10095	COG0210	DNA helicase
EP20_RS10105	COG4496	protein, YerC YecD
EP20_RS10140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EP20_RS10150	COG0077	Prephenate dehydratase
EP20_RS10160	COG0471	metal ion transport
EP20_RS10170	COG1335	isochorismatase
EP20_RS10185	COG1012	belongs to the aldehyde dehydrogenase family
EP20_RS10235	COG1131	(ABC) transporter
EP20_RS10250	COG1725	Transcriptional regulator
EP20_RS10310	COG0860	N-Acetylmuramoyl-L-alanine amidase
EP20_RS10310	COG1388	LysM domain
EP20_RS10320	COG5632	N-Acetylmuramoyl-L-alanine amidase
EP20_RS10320	COG1388	LysM domain
EP20_RS10360	COG0739	heme binding
EP20_RS10415	COG4695	Portal protein
EP20_RS10635	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EP20_RS10640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EP20_RS10645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EP20_RS10660	COG3728	DNA packaging
EP20_RS10660	COG5484	DNA packaging
EP20_RS10735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EP20_RS10740	COG1621	beta-fructofuranosidase activity
EP20_RS10745	COG1609	Transcriptional regulator
EP20_RS10750	COG0004	ammonium transporteR
EP20_RS10755	COG0425	Belongs to the sulfur carrier protein TusA family
EP20_RS10760	COG2391	methyltransferase activity
EP20_RS10770	COG0488	(ABC) transporter
EP20_RS10780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EP20_RS10790	COG0456	acetyltransferase
EP20_RS10795	COG1214	PFAM Peptidase M22, glycoprotease
EP20_RS10800	COG0802	atpase or kinase
EP20_RS10815	COG0028	Belongs to the TPP enzyme family
EP20_RS10890	COG2183	response to ionizing radiation
EP20_RS10895	COG1191	sigma factor activity
EP20_RS10905	COG1366	Belongs to the anti-sigma-factor antagonist family
EP20_RS10910	COG2208	phosphoserine phosphatase activity
EP20_RS10945	COG3428	Bacterial PH domain
EP20_RS10975	COG2205	protein histidine kinase activity
EP20_RS10980	COG0745	RESPONSE REGULATOR receiver
EP20_RS10990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EP20_RS11000	COG0772	Belongs to the SEDS family
EP20_RS11015	COG1937	Protein conserved in bacteria
EP20_RS11025	COG1418	mRNA catabolic process
EP20_RS11075	COG0629	single-stranded DNA binding
EP20_RS11150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EP20_RS11175	COG0009	L-threonylcarbamoyladenylate synthase
EP20_RS11180	COG2890	protein-(glutamine-N5) methyltransferase activity
EP20_RS11200	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EP20_RS11240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EP20_RS11295	COG0813	purine-nucleoside phosphorylase activity
EP20_RS11300	COG0783	Belongs to the Dps family
EP20_RS11320	COG1482	cell wall glycoprotein biosynthetic process
EP20_RS11325	COG0702	epimerase
EP20_RS11330	COG0640	Transcriptional regulator
EP20_RS11365	COG0561	phosphatase activity
EP20_RS11370	COG1119	ATPase activity
EP20_RS11385	COG3711	transcriptional antiterminator
EP20_RS11415	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EP20_RS11480	COG0489	protein tyrosine kinase activity
EP20_RS11485	COG2814	Major facilitator Superfamily
EP20_RS11500	COG1272	protein, Hemolysin III
EP20_RS11510	COG1988	membrane-bound metal-dependent
EP20_RS11520	COG3314	Sporulation integral membrane protein YlbJ
EP20_RS11525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EP20_RS11530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EP20_RS11535	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EP20_RS11545	COG3457	Alanine racemase
EP20_RS11550	COG4264	IucA IucC family
EP20_RS11555	COG2814	Major facilitator Superfamily
EP20_RS11595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EP20_RS11605	COG2130	NADP-dependent
EP20_RS11655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EP20_RS11675	COG0656	L-ascorbic acid biosynthetic process
EP20_RS11680	COG0789	Transcriptional regulator
EP20_RS11690	COG5492	domain, Protein
EP20_RS11710	COG3527	Alpha-acetolactate decarboxylase
EP20_RS11715	COG0028	Belongs to the TPP enzyme family
EP20_RS11735	COG0542	response to heat
EP20_RS11825	COG0201	protein transport
EP20_RS11940	COG2252	PERMEase
EP20_RS11985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EP20_RS12055	COG1763	Mo-molybdopterin cofactor biosynthetic process
EP20_RS12075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EP20_RS12080	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EP20_RS12085	COG4149	molybdate abc transporter
EP20_RS12090	COG0725	ABC transporter, periplasmic molybdate-binding protein
EP20_RS12105	COG1268	BioY protein
EP20_RS12120	COG1960	acyl-CoA dehydrogenase activity
EP20_RS12125	COG4413	Urea transporter
EP20_RS12190	COG3942	CHAP domain
EP20_RS12200	COG1757	Na H antiporter
EP20_RS12215	COG3942	CHAP domain
EP20_RS12290	COG1113	amino acid transport
EP20_RS12310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EP20_RS12315	COG0385	Bile acid
EP20_RS12325	COG1263	PTS System
EP20_RS12325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EP20_RS12330	COG1737	Transcriptional regulator
EP20_RS12350	COG1028	Short-chain dehydrogenase reductase Sdr
EP20_RS12355	COG1473	amidohydrolase
EP20_RS12370	COG0583	DNA-binding transcription factor activity
EP20_RS12395	COG2258	MOSC domain
EP20_RS12415	COG1668	transmembrane transport
EP20_RS12420	COG4152	abc transporter atp-binding protein
EP20_RS12425	COG3152	Membrane
EP20_RS12435	COG0786	glutamate:sodium symporter activity
EP20_RS12445	COG0598	Magnesium transport protein CorA
EP20_RS12460	COG0657	acetylesterase activity
EP20_RS12470	COG2814	Major facilitator Superfamily
EP20_RS12475	COG1566	PFAM secretion protein HlyD family protein
EP20_RS12485	COG2814	Major facilitator Superfamily
EP20_RS12555	COG1620	l-lactate permease
EP20_RS12575	COG0604	alcohol dehydrogenase
EP20_RS12580	COG0456	acetyltransferase
EP20_RS12605	COG1511	domain protein
EP20_RS12620	COG1263	PTS System
EP20_RS12620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EP20_RS12635	COG3871	stress protein (general stress protein 26)
EP20_RS12675	COG0789	Transcriptional regulator
EP20_RS12695	COG2181	nitrate reductase activity
EP20_RS12705	COG1140	nitrate reductase beta subunit
EP20_RS12710	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EP20_RS12720	COG2146	nitrite reductase [NAD(P)H] activity
EP20_RS12725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EP20_RS12735	COG0454	-acetyltransferase
EP20_RS12740	COG2116	formate transmembrane transporter activity
EP20_RS12755	COG0803	Belongs to the bacterial solute-binding protein 9 family
EP20_RS12755	COG3443	Belongs to the bacterial solute-binding protein 9 family
EP20_RS12790	COG1126	abc transporter atp-binding protein
EP20_RS12795	COG0765	amino acid transport
EP20_RS12800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EP20_RS12805	COG2814	Major facilitator Superfamily
EP20_RS12825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EP20_RS12870	COG0156	8-amino-7-oxononanoate synthase activity
EP20_RS12880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EP20_RS12885	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EP20_RS12900	COG1132	(ABC) transporter
EP20_RS12905	COG1132	(ABC) transporter
EP20_RS12905	COG2375	cellular response to nickel ion
EP20_RS12925	COG1929	Belongs to the glycerate kinase type-1 family
EP20_RS12935	COG2814	Major facilitator Superfamily
EP20_RS12955	COG1113	amino acid transport
EP20_RS12970	COG0531	amino acid
EP20_RS12995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EP20_RS13005	COG1174	glycine betaine transport
EP20_RS13015	COG1174	glycine betaine transport
EP20_RS13035	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EP20_RS13045	COG2272	Belongs to the type-B carboxylesterase lipase family
EP20_RS13050	COG2814	Major facilitator Superfamily
EP20_RS13055	COG0390	transport system, permease component
EP20_RS13060	COG4619	ABC transporter
EP20_RS13065	COG1363	Peptidase, m42
EP20_RS13085	COG4808	Protein conserved in bacteria
EP20_RS13105	COG1124	(ABC) transporter
EP20_RS13110	COG0444	Belongs to the ABC transporter superfamily
EP20_RS13115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EP20_RS13120	COG0601	transmembrane transport
EP20_RS13125	COG0747	negative chemotaxis
EP20_RS13155	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EP20_RS13160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EP20_RS13245	COG0494	nUDIX hydrolase
EP20_RS13280	COG1846	Transcriptional regulator
EP20_RS13285	COG1846	Transcriptional regulator
EP20_RS13315	COG1070	Carbohydrate kinase
EP20_RS13320	COG1802	Transcriptional regulator
EP20_RS13325	COG0789	Transcriptional regulator
EP20_RS13330	COG2357	RelA SpoT domain protein
EP20_RS13335	COG4876	unkown
EP20_RS13345	COG2271	Major facilitator Superfamily
EP20_RS13350	COG0586	Pfam SNARE associated Golgi protein
EP20_RS13360	COG2814	Major facilitator Superfamily
EP20_RS13365	COG1846	Transcriptional regulator
EP20_RS13370	COG1131	(ABC) transporter
EP20_RS13390	COG3949	Membrane
EP20_RS13395	COG0400	carboxylic ester hydrolase activity
EP20_RS13400	COG0346	lactoylglutathione lyase activity
EP20_RS13405	COG1846	Transcriptional regulator
EP20_RS13415	COG2514	catechol 2,3-dioxygenase activity
EP20_RS13430	COG0561	phosphatase activity
EP20_RS13435	COG1131	(ABC) transporter
EP20_RS13445	COG3764	Sortase (surface protein transpeptidase)
EP20_RS13465	COG1760	l-serine dehydratase
EP20_RS13470	COG1760	l-serine dehydratase
EP20_RS13485	COG0697	spore germination
EP20_RS13490	COG0657	acetylesterase activity
EP20_RS13510	COG0028	Belongs to the TPP enzyme family
EP20_RS13525	COG0583	DNA-binding transcription factor activity
EP20_RS13535	COG3942	CHAP domain
EP20_RS13560	COG3425	synthase
EP20_RS13565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EP20_RS13570	COG0542	response to heat
EP20_RS13590	COG2409	Drug exporters of the RND superfamily
EP20_RS13635	COG0436	Aminotransferase
EP20_RS13665	COG3942	CHAP domain
EP20_RS13670	COG2755	lipolytic protein G-D-S-L family
EP20_RS13670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EP20_RS13740	COG0596	Alpha beta hydrolase
EP20_RS13775	COG3001	Fructosamine kinase
EP20_RS13780	COG0167	dihydroorotate dehydrogenase activity
EP20_RS13830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EP20_RS13835	COG3527	Alpha-acetolactate decarboxylase
EP20_RS13850	COG0531	amino acid
EP20_RS13880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EP20_RS13900	COG1012	belongs to the aldehyde dehydrogenase family
EP20_RS13910	COG1510	regulation of RNA biosynthetic process
EP20_RS13920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EP20_RS13945	COG2851	Citrate transporter
EP20_RS13960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EP20_RS13970	COG0386	Belongs to the glutathione peroxidase family
EP20_RS13995	COG1136	(ABC) transporter
EP20_RS14000	COG2205	protein histidine kinase activity
EP20_RS14005	COG0745	RESPONSE REGULATOR receiver
EP20_RS14020	COG1785	Belongs to the alkaline phosphatase family
EP20_RS14025	COG1846	Transcriptional regulator
EP20_RS14070	COG1438	arginine binding
EP20_RS14090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EP20_RS14090	COG3711	transcriptional antiterminator
EP20_RS14095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EP20_RS14095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EP20_RS14095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EP20_RS14100	COG1482	cell wall glycoprotein biosynthetic process
EP20_RS14110	COG3942	CHAP domain
EP20_RS14110	COG1705	Flagellar rod assembly protein muramidase FlgJ
EP20_RS14115	COG3433	isochorismatase activity
EP20_RS14115	COG1535	isochorismatase
EP20_RS14130	COG0438	transferase activity, transferring glycosyl groups
EP20_RS14145	COG1073	alpha beta
EP20_RS14165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EP20_RS14185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EP20_RS14240	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EP20_RS14275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EP20_RS14360	COG0471	metal ion transport
EP20_RS14365	COG2962	Rard protein
EP20_RS14375	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EP20_RS14390	COG1136	(ABC) transporter
EP20_RS14395	COG0577	efflux transmembrane transporter activity
EP20_RS14420	COG1278	Cold shock
EP20_RS14440	COG1475	DNA binding
EP20_RS14650	COG0584	glycerophosphoryl diester phosphodiesterase