locus-tag	class	description
ASL18_RS00015	COG2501	S4 domain
ASL18_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASL18_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASL18_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ASL18_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
ASL18_RS00110	COG4863	YycH protein
ASL18_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ASL18_RS00125	COG0737	Belongs to the 5'-nucleotidase family
ASL18_RS00150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASL18_RS00150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASL18_RS00190	COG2003	Belongs to the UPF0758 family
ASL18_RS00220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASL18_RS00260	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ASL18_RS00295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASL18_RS00345	COG0584	glycerophosphoryl diester phosphodiesterase
ASL18_RS00350	COG2030	dehydratase
ASL18_RS00370	COG1846	Transcriptional regulator
ASL18_RS00370	COG1940	carbohydrate kinase activity
ASL18_RS00380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASL18_RS00385	COG2210	Belongs to the sulfur carrier protein TusA family
ASL18_RS00390	COG1937	Protein conserved in bacteria
ASL18_RS00395	COG0730	response to heat
ASL18_RS00425	COG2003	Belongs to the UPF0758 family
ASL18_RS00485	COG1401	restriction endodeoxyribonuclease activity
ASL18_RS00490	COG4268	DNA restriction-modification system
ASL18_RS00510	COG2814	Major facilitator Superfamily
ASL18_RS00530	COG0456	acetyltransferase
ASL18_RS00565	COG0823	Involved in the tonB-independent uptake of proteins
ASL18_RS00580	COG1473	amidohydrolase
ASL18_RS00590	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASL18_RS00595	COG4716	Myosin-crossreactive antigen
ASL18_RS00605	COG1620	l-lactate permease
ASL18_RS00620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASL18_RS00625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASL18_RS00630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASL18_RS00640	COG2423	ornithine cyclodeaminase activity
ASL18_RS00645	COG4264	IucA IucC family
ASL18_RS00650	COG2814	Major facilitator Superfamily
ASL18_RS00655	COG4264	IucA IucC family
ASL18_RS00660	COG4264	IucA IucC family
ASL18_RS00670	COG0019	diaminopimelate decarboxylase activity
ASL18_RS00675	COG1475	DNA binding
ASL18_RS00700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASL18_RS00705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASL18_RS00710	COG0438	transferase activity, transferring glycosyl groups
ASL18_RS00745	COG0813	purine-nucleoside phosphorylase activity
ASL18_RS00750	COG2814	Major facilitator Superfamily
ASL18_RS00770	COG3639	organic phosphonate transmembrane transporter activity
ASL18_RS00790	COG0737	Belongs to the 5'-nucleotidase family
ASL18_RS00805	COG1012	belongs to the aldehyde dehydrogenase family
ASL18_RS00805	COG1454	alcohol dehydrogenase
ASL18_RS00830	COG1086	Polysaccharide biosynthesis protein
ASL18_RS00840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASL18_RS00870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASL18_RS00880	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASL18_RS00885	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASL18_RS00895	COG2832	Protein of unknown function (DUF454)
ASL18_RS00930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASL18_RS00935	COG1960	acyl-CoA dehydrogenase activity
ASL18_RS00940	COG5609	conserved protein (DUF2294)
ASL18_RS00990	COG1114	Component of the transport system for branched-chain amino acids
ASL18_RS00995	COG1335	isochorismatase
ASL18_RS01000	COG3961	Belongs to the TPP enzyme family
ASL18_RS01025	COG1737	Transcriptional regulator
ASL18_RS01050	COG0601	transmembrane transport
ASL18_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASL18_RS01065	COG0405	Gamma-glutamyltransferase
ASL18_RS01080	COG3842	ATPase activity
ASL18_RS01090	COG1175	transmembrane transport
ASL18_RS01095	COG3833	ABC-type maltose transport systems, permease component
ASL18_RS01100	COG0673	inositol 2-dehydrogenase activity
ASL18_RS01105	COG0673	inositol 2-dehydrogenase activity
ASL18_RS01115	COG1755	Isoprenylcysteine carboxyl methyltransferase
ASL18_RS01180	COG0183	Belongs to the thiolase family
ASL18_RS01190	COG1960	acyl-CoA dehydrogenase activity
ASL18_RS01195	COG0318	PFAM AMP-dependent synthetase and ligase
ASL18_RS01215	COG0747	negative chemotaxis
ASL18_RS01220	COG3189	MarR family transcriptional regulator
ASL18_RS01250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASL18_RS01250	COG2190	(PTS) system
ASL18_RS01250	COG1263	PTS System
ASL18_RS01255	COG1957	nucleoside hydrolase
ASL18_RS01275	COG3414	Phosphotransferase system galactitol-specific IIB component
ASL18_RS01280	COG3775	system Galactitol-specific IIC component
ASL18_RS01285	COG1063	alcohol dehydrogenase
ASL18_RS01295	COG1063	alcohol dehydrogenase
ASL18_RS01305	COG1063	alcohol dehydrogenase
ASL18_RS01310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASL18_RS01320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASL18_RS01330	COG1063	alcohol dehydrogenase
ASL18_RS01335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASL18_RS01375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASL18_RS01380	COG1263	PTS System
ASL18_RS01380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASL18_RS01380	COG2190	(PTS) system
ASL18_RS01385	COG2723	6-phospho-beta-galactosidase activity
ASL18_RS01395	COG2226	methyltransferase
ASL18_RS01450	COG1131	(ABC) transporter
ASL18_RS01470	COG1388	LysM domain
ASL18_RS01470	COG3942	CHAP domain
ASL18_RS01610	COG1114	Component of the transport system for branched-chain amino acids
ASL18_RS01615	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ASL18_RS01625	COG0577	efflux transmembrane transporter activity
ASL18_RS01650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASL18_RS01655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASL18_RS01680	COG3314	Sporulation integral membrane protein YlbJ
ASL18_RS01690	COG0582	viral genome integration into host DNA
ASL18_RS01715	COG1396	sequence-specific DNA binding
ASL18_RS02000	COG1388	LysM domain
ASL18_RS02000	COG5632	N-Acetylmuramoyl-L-alanine amidase
ASL18_RS02020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASL18_RS02050	COG3037	sugar-specific permease SgaT UlaA
ASL18_RS02060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASL18_RS02065	COG3711	transcriptional antiterminator
ASL18_RS02085	COG2271	Major facilitator Superfamily
ASL18_RS02090	COG0346	lactoylglutathione lyase activity
ASL18_RS02095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASL18_RS02100	COG0431	NADPH-dependent FMN reductase
ASL18_RS02115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASL18_RS02130	COG0672	)-iron permease
ASL18_RS02135	COG0805	protein transport
ASL18_RS02140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASL18_RS02150	COG1476	TRANSCRIPTIONal
ASL18_RS02160	COG1131	(ABC) transporter
ASL18_RS02195	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASL18_RS02195	COG0646	methionine synthase
ASL18_RS02200	COG0626	cystathionine gamma-synthase activity
ASL18_RS02205	COG0626	cystathionine gamma-synthase activity
ASL18_RS02210	COG1475	DNA binding
ASL18_RS02215	COG0668	transmembrane transport
ASL18_RS02220	COG4481	Protein conserved in bacteria
ASL18_RS02225	COG0012	GTP binding
ASL18_RS02255	COG4974	Belongs to the 'phage' integrase family
ASL18_RS02315	COG3634	alkyl hydroperoxide reductase activity
ASL18_RS02330	COG1823	symporter activity
ASL18_RS02360	COG2233	PERMEase
ASL18_RS02375	COG0582	viral genome integration into host DNA
ASL18_RS02410	COG0791	NLP P60 protein
ASL18_RS02410	COG0741	lytic transglycosylase activity
ASL18_RS02480	COG2946	Replication initiation factor
ASL18_RS02485	COG1674	ftsk spoiiie
ASL18_RS02540	COG3759	membrane
ASL18_RS02680	COG0523	cobalamin synthesis protein
ASL18_RS02690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASL18_RS02700	COG5609	conserved protein (DUF2294)
ASL18_RS02715	COG1647	Serine aminopeptidase, S33
ASL18_RS02725	COG0733	neurotransmitter:sodium symporter activity
ASL18_RS02730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASL18_RS02735	COG0626	cystathionine gamma-synthase activity
ASL18_RS02745	COG2011	ABC-type metal ion transport system permease component
ASL18_RS02750	COG1464	Belongs to the NlpA lipoprotein family
ASL18_RS02785	COG0583	DNA-binding transcription factor activity
ASL18_RS02790	COG0070	glutamate synthase
ASL18_RS02790	COG0069	glutamate synthase activity
ASL18_RS02790	COG0067	glutamate synthase
ASL18_RS02795	COG0493	'glutamate synthase
ASL18_RS02805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASL18_RS02805	COG1263	PTS System
ASL18_RS02810	COG0366	Alpha amylase catalytic
ASL18_RS02815	COG2188	Transcriptional regulator
ASL18_RS02835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASL18_RS02870	COG1982	Orn Lys Arg decarboxylase major
ASL18_RS02880	COG3870	Protein conserved in bacteria
ASL18_RS02890	COG0470	DNA polymerase III
ASL18_RS02895	COG1774	PSP1 C-terminal conserved region
ASL18_RS02905	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ASL18_RS02915	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASL18_RS02930	COG0084	hydrolase, TatD family'
ASL18_RS02935	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ASL18_RS02945	COG4466	Protein conserved in bacteria
ASL18_RS02955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASL18_RS02960	COG0251	oxidation-reduction process
ASL18_RS03005	COG2244	polysaccharide biosynthetic process
ASL18_RS03065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASL18_RS03145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASL18_RS03160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASL18_RS03170	COG3880	PFAM UvrB UvrC protein
ASL18_RS03190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASL18_RS03195	COG4956	integral membrane protein (PIN domain superfamily)
ASL18_RS03215	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ASL18_RS03265	COG2813	Specifically methylates the guanine in position
ASL18_RS03305	COG1473	amidohydrolase
ASL18_RS03335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASL18_RS03340	COG1428	Deoxynucleoside kinase
ASL18_RS03345	COG1428	Deoxynucleoside kinase
ASL18_RS03355	COG0561	phosphatase activity
ASL18_RS03395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ASL18_RS03410	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ASL18_RS03500	COG0095	Lipoate-protein ligase
ASL18_RS03510	COG0083	homoserine kinase activity
ASL18_RS03530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASL18_RS03615	COG0667	Aldo Keto reductase
ASL18_RS03620	COG0655	NAD(P)H dehydrogenase (quinone) activity
ASL18_RS03630	COG1078	dGTPase activity
ASL18_RS03665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASL18_RS03670	COG4139	cobalamin transport
ASL18_RS03720	COG4974	Belongs to the 'phage' integrase family
ASL18_RS03765	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASL18_RS03770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASL18_RS03775	COG1121	(ABC) transporter
ASL18_RS03780	COG1321	iron dependent repressor
ASL18_RS03790	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ASL18_RS03800	COG1682	transport, permease protein
ASL18_RS03805	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASL18_RS03810	COG1216	Glycosyl transferase, family 2
ASL18_RS03815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASL18_RS03820	COG1686	Belongs to the peptidase S11 family
ASL18_RS03825	COG1132	(ABC) transporter
ASL18_RS03830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASL18_RS03840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ASL18_RS03845	COG1120	ATPase activity
ASL18_RS03850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASL18_RS03855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASL18_RS03860	COG2376	Dihydroxyacetone kinase
ASL18_RS03870	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ASL18_RS03880	COG3949	Membrane
ASL18_RS03905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASL18_RS03920	COG1136	(ABC) transporter
ASL18_RS03925	COG0577	efflux transmembrane transporter activity
ASL18_RS03930	COG1392	Phosphate transport regulator
ASL18_RS03935	COG0306	phosphate transporter
ASL18_RS03940	COG1388	LysM domain
ASL18_RS03940	COG3942	CHAP domain
ASL18_RS03950	COG4977	sequence-specific DNA binding
ASL18_RS03950	COG1917	Cupin 2, conserved barrel domain protein
ASL18_RS03980	COG0583	DNA-binding transcription factor activity
ASL18_RS03990	COG2814	Major facilitator Superfamily
ASL18_RS03995	COG2839	Protein conserved in bacteria
ASL18_RS04025	COG1611	Belongs to the LOG family
ASL18_RS04045	COG4988	ABC transporter
ASL18_RS04060	COG0523	cobalamin synthesis protein
ASL18_RS04065	COG4989	oxidoreductase activity
ASL18_RS04075	COG0471	metal ion transport
ASL18_RS04080	COG0415	Belongs to the DNA photolyase family
ASL18_RS04110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASL18_RS04115	COG1349	DNA-binding transcription factor activity
ASL18_RS04120	COG1105	Belongs to the carbohydrate kinase PfkB family
ASL18_RS04125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASL18_RS04125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASL18_RS04125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASL18_RS04135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASL18_RS04140	COG1253	flavin adenine dinucleotide binding
ASL18_RS04145	COG0656	L-ascorbic acid biosynthetic process
ASL18_RS04150	COG0463	Glycosyl transferase, family 2
ASL18_RS04185	COG0720	synthase
ASL18_RS04195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASL18_RS04195	COG0512	Glutamine amidotransferase of anthranilate synthase
ASL18_RS04200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASL18_RS04235	COG0488	(ABC) transporter
ASL18_RS04240	COG0514	ATP-dependent DNA helicase (RecQ)
ASL18_RS04245	COG0517	IMP dehydrogenase activity
ASL18_RS04245	COG1125	glycine betaine transport
ASL18_RS04250	COG1174	glycine betaine transport
ASL18_RS04280	COG3104	oligopeptide transport
ASL18_RS04300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASL18_RS04305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASL18_RS04320	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASL18_RS04325	COG4605	iron ion homeostasis
ASL18_RS04330	COG4604	ABC transporter, ATP-binding protein
ASL18_RS04335	COG4607	ABC-type enterochelin transport system periplasmic component
ASL18_RS04390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASL18_RS04395	COG1739	Uncharacterized protein family UPF0029
ASL18_RS04405	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ASL18_RS04410	COG1040	competence protein
ASL18_RS04440	COG1388	LysM domain
ASL18_RS04440	COG3942	CHAP domain
ASL18_RS04500	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASL18_RS04565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASL18_RS04570	COG1647	Serine aminopeptidase, S33
ASL18_RS04575	COG0557	exoribonuclease II activity
ASL18_RS04625	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ASL18_RS04625	COG3266	domain, Protein
ASL18_RS04650	COG1278	Cold shock
ASL18_RS04690	COG0406	alpha-ribazole phosphatase activity
ASL18_RS04695	COG1279	arginine transmembrane transporter activity
ASL18_RS04720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASL18_RS04725	COG1393	Belongs to the ArsC family
ASL18_RS04740	COG3878	Protein conserved in bacteria
ASL18_RS04750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ASL18_RS04765	COG2011	ABC-type metal ion transport system permease component
ASL18_RS04770	COG1464	Belongs to the NlpA lipoprotein family
ASL18_RS04775	COG0582	viral genome integration into host DNA
ASL18_RS04870	COG3728	DNA packaging
ASL18_RS04870	COG5484	DNA packaging
ASL18_RS04900	COG0396	ATPase activity
ASL18_RS04905	COG0719	Fe-S assembly protein
ASL18_RS04915	COG0822	iron-sulfur transferase activity
ASL18_RS04935	COG1253	flavin adenine dinucleotide binding
ASL18_RS04950	COG1801	Protein of unknown function DUF72
ASL18_RS04955	COG0730	response to heat
ASL18_RS04970	COG4470	Protein conserved in bacteria
ASL18_RS04980	COG2445	Protein of unknown function DUF86
ASL18_RS05010	COG1696	Membrane protein involved in D-alanine export
ASL18_RS05020	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ASL18_RS05025	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ASL18_RS05030	COG4837	Protein of unknown function (DUF1462)
ASL18_RS05035	COG1252	NADH dehydrogenase
ASL18_RS05045	COG0316	Belongs to the HesB IscA family
ASL18_RS05055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASL18_RS05060	COG2056	Na+-H+ antiporter family
ASL18_RS05065	COG2050	protein possibly involved in aromatic compounds catabolism
ASL18_RS05120	COG1098	S1 RNA binding domain
ASL18_RS05125	COG1902	pentaerythritol trinitrate reductase activity
ASL18_RS05145	COG0584	glycerophosphoryl diester phosphodiesterase
ASL18_RS05165	COG0398	Pfam SNARE associated Golgi protein
ASL18_RS05205	COG0561	phosphatase activity
ASL18_RS05230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASL18_RS05245	COG1881	PFAM PEBP family protein
ASL18_RS05275	COG0601	transmembrane transport
ASL18_RS05280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASL18_RS05285	COG0444	Belongs to the ABC transporter superfamily
ASL18_RS05290	COG4608	Belongs to the ABC transporter superfamily
ASL18_RS05295	COG4166	transmembrane transport
ASL18_RS05300	COG0747	negative chemotaxis
ASL18_RS05305	COG0444	Belongs to the ABC transporter superfamily
ASL18_RS05310	COG4608	Belongs to the ABC transporter superfamily
ASL18_RS05315	COG0601	transmembrane transport
ASL18_RS05320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASL18_RS05345	COG1164	Oligoendopeptidase f
ASL18_RS05355	COG2346	COG2346, Truncated hemoglobins
ASL18_RS05370	COG2357	RelA SpoT domain protein
ASL18_RS05380	COG0564	pseudouridine synthase activity
ASL18_RS05385	COG2239	Acts as a magnesium transporter
ASL18_RS05390	COG0475	glutathione-regulated potassium exporter activity
ASL18_RS05390	COG0569	domain protein
ASL18_RS05400	COG0628	permease
ASL18_RS05405	COG1115	amino acid carrier protein
ASL18_RS05445	COG0861	Integral membrane protein TerC family
ASL18_RS05455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASL18_RS05460	COG0737	Belongs to the 5'-nucleotidase family
ASL18_RS05475	COG4903	ComK protein
ASL18_RS05490	COG4873	Protein conserved in bacteria
ASL18_RS05545	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ASL18_RS05555	COG2314	TM2 domain
ASL18_RS05560	COG0456	acetyltransferase
ASL18_RS05565	COG1575	Belongs to the MenA family. Type 1 subfamily
ASL18_RS05570	COG1169	isochorismate synthase
ASL18_RS05580	COG2267	carboxylic ester hydrolase activity
ASL18_RS05605	COG0436	Aminotransferase
ASL18_RS05615	COG3594	Acyltransferase
ASL18_RS05645	COG1316	TRANSCRIPTIONal
ASL18_RS05650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASL18_RS05690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASL18_RS05705	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASL18_RS05735	COG0138	bifunctional purine biosynthesis protein purh
ASL18_RS05745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ASL18_RS05750	COG4172	Belongs to the ABC transporter superfamily
ASL18_RS05755	COG4721	ABC-type cobalt transport system, permease component
ASL18_RS05775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASL18_RS05800	COG1271	oxidase subunit
ASL18_RS05805	COG1294	oxidase, subunit
ASL18_RS05810	COG0569	domain protein
ASL18_RS05880	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASL18_RS05885	COG1177	transmembrane transport
ASL18_RS05890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASL18_RS05915	COG0483	inositol monophosphate 1-phosphatase activity
ASL18_RS05925	COG1217	gtp-binding protein TYPA
ASL18_RS05935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ASL18_RS05945	COG0772	Belongs to the SEDS family
ASL18_RS05980	COG3679	Belongs to the UPF0342 family
ASL18_RS06000	COG0742	ribosomal rna small subunit methyltransferase
ASL18_RS06120	COG0305	Participates in initiation and elongation during chromosome replication
ASL18_RS06180	COG0756	dUTP diphosphatase activity
ASL18_RS06235	COG0740	serine-type endopeptidase activity
ASL18_RS06280	COG0739	heme binding
ASL18_RS06320	COG1388	LysM domain
ASL18_RS06320	COG5632	N-Acetylmuramoyl-L-alanine amidase
ASL18_RS06360	COG4509	Sortase family
ASL18_RS06375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASL18_RS06405	COG1796	DNA polymerase
ASL18_RS06405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ASL18_RS06430	COG2009	succinate dehydrogenase
ASL18_RS06435	COG1053	succinate dehydrogenase
ASL18_RS06440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASL18_RS06565	COG1288	antiporter activity
ASL18_RS06600	COG1011	Hydrolase
ASL18_RS06625	COG4839	cell division protein FtsL
ASL18_RS06630	COG0768	penicillin binding
ASL18_RS06645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASL18_RS06650	COG0849	cell division
ASL18_RS06665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASL18_RS06675	COG0762	integral membrane protein
ASL18_RS06685	COG3599	regulation of cell shape
ASL18_RS06695	COG2514	catechol 2,3-dioxygenase activity
ASL18_RS06710	COG0564	pseudouridine synthase activity
ASL18_RS06720	COG2233	PERMEase
ASL18_RS06765	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ASL18_RS06780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASL18_RS06785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASL18_RS06795	COG2314	TM2 domain
ASL18_RS06810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASL18_RS06810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASL18_RS06820	COG0631	protein serine/threonine phosphatase activity
ASL18_RS06835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASL18_RS06850	COG1302	Protein conserved in bacteria
ASL18_RS06860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASL18_RS06900	COG1196	nuclear chromosome segregation
ASL18_RS06905	COG0552	protein localization to endoplasmic reticulum
ASL18_RS06915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASL18_RS06980	COG0758	DNA mediated transformation
ASL18_RS07075	COG0195	Participates in both transcription termination and antitermination
ASL18_RS07080	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ASL18_RS07105	COG0196	riboflavin kinase activity
ASL18_RS07130	COG2188	Transcriptional regulator
ASL18_RS07135	COG0612	Peptidase, M16
ASL18_RS07140	COG0612	Peptidase, M16
ASL18_RS07145	COG0300	oxidoreductase activity
ASL18_RS07165	COG1058	Belongs to the CinA family
ASL18_RS07165	COG1546	Belongs to the CinA family
ASL18_RS07185	COG1692	metallophosphoesterase
ASL18_RS07190	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASL18_RS07190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ASL18_RS07195	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASL18_RS07230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ASL18_RS07235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASL18_RS07260	COG1923	regulation of RNA biosynthetic process
ASL18_RS07270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASL18_RS07275	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ASL18_RS07280	COG0789	Transcriptional regulator
ASL18_RS07405	COG1131	(ABC) transporter
ASL18_RS07420	COG2197	response regulator
ASL18_RS07430	COG1525	nuclease
ASL18_RS07445	COG0527	aspartate kinase activity
ASL18_RS07450	COG0460	homoserine dehydrogenase
ASL18_RS07455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASL18_RS07480	COG0833	amino acid
ASL18_RS07510	COG2340	Cysteine-rich secretory protein family
ASL18_RS07545	COG4846	Membrane protein involved in cytochrome C biogenesis
ASL18_RS07565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASL18_RS07575	COG0824	Thioesterase
ASL18_RS07605	COG1115	amino acid carrier protein
ASL18_RS07620	COG0628	permease
ASL18_RS07630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ASL18_RS07630	COG0392	lysyltransferase activity
ASL18_RS07650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASL18_RS07660	COG1363	Peptidase, m42
ASL18_RS07665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASL18_RS07670	COG0512	Glutamine amidotransferase of anthranilate synthase
ASL18_RS07710	COG0561	phosphatase activity
ASL18_RS07755	COG0704	Plays a role in the regulation of phosphate uptake
ASL18_RS07765	COG0581	inorganic phosphate transmembrane transporter activity
ASL18_RS07770	COG0573	inorganic phosphate transmembrane transporter activity
ASL18_RS07790	COG0488	(ABC) transporter
ASL18_RS07795	COG0527	aspartate kinase activity
ASL18_RS07800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASL18_RS07885	COG4548	von Willebrand factor, type A
ASL18_RS07890	COG0714	Associated with various cellular activities
ASL18_RS07940	COG0671	phosphoesterase, PA-phosphatase related
ASL18_RS08005	COG1413	lyase activity
ASL18_RS08020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASL18_RS08050	COG0531	amino acid
ASL18_RS08065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASL18_RS08070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ASL18_RS08090	COG0116	Belongs to the methyltransferase superfamily
ASL18_RS08125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASL18_RS08125	COG4499	WXG100 protein secretion system (Wss), protein YukC
ASL18_RS08135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASL18_RS08140	COG3935	DnaD domain protein
ASL18_RS08165	COG0438	transferase activity, transferring glycosyl groups
ASL18_RS08170	COG1694	Mazg nucleotide pyrophosphohydrolase
ASL18_RS08175	COG2738	Putative neutral zinc metallopeptidase
ASL18_RS08180	COG4347	Protein of unknown function (DUF1405)
ASL18_RS08220	COG0142	geranyltranstransferase activity
ASL18_RS08285	COG0492	ferredoxin-NADP+ reductase activity
ASL18_RS08300	COG0514	ATP-dependent DNA helicase (RecQ)
ASL18_RS08310	COG1141	Ferredoxin
ASL18_RS08355	COG5002	protein histidine kinase activity
ASL18_RS08360	COG0745	RESPONSE REGULATOR receiver
ASL18_RS08365	COG1187	pseudouridine synthase activity
ASL18_RS08390	COG0735	belongs to the Fur family
ASL18_RS08395	COG0494	nUDIX hydrolase
ASL18_RS08400	COG0667	Aldo Keto reductase
ASL18_RS08410	COG4221	oxidoreductase activity
ASL18_RS08425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASL18_RS08435	COG0366	Alpha amylase catalytic
ASL18_RS08440	COG1609	Transcriptional regulator
ASL18_RS08460	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASL18_RS08470	COG4129	membrane
ASL18_RS08480	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASL18_RS08485	COG0022	dehydrogenase e1 component
ASL18_RS08490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ASL18_RS08495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASL18_RS08500	COG0497	DNA recombination
ASL18_RS08530	COG1302	Protein conserved in bacteria
ASL18_RS08535	COG0439	Biotin carboxylase
ASL18_RS08540	COG0511	ligase activity, forming carbon-carbon bonds
ASL18_RS08550	COG0006	proline dipeptidase activity
ASL18_RS08565	COG0095	Lipoate-protein ligase
ASL18_RS08570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASL18_RS08615	COG4537	Required for transformation and DNA binding
ASL18_RS08620	COG1459	type II secretion system
ASL18_RS08625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASL18_RS08630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASL18_RS08635	COG0011	TIGRFAM Protein of
ASL18_RS08640	COG1940	carbohydrate kinase activity
ASL18_RS08645	COG4483	Protein conserved in bacteria
ASL18_RS08655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASL18_RS08665	COG0768	penicillin binding
ASL18_RS08680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASL18_RS08685	COG1121	(ABC) transporter
ASL18_RS08695	COG0513	Belongs to the DEAD box helicase family
ASL18_RS08705	COG2384	SAM-dependent methyltransferase
ASL18_RS08725	COG0517	IMP dehydrogenase activity
ASL18_RS08760	COG1702	phosphate starvation-inducible protein PhoH
ASL18_RS08775	COG1030	water channel activity
ASL18_RS08785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASL18_RS08790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASL18_RS08820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASL18_RS08840	COG1466	dna polymerase III delta subunit
ASL18_RS08845	COG2333	competence protein COMEC
ASL18_RS08845	COG0658	competence protein
ASL18_RS08850	COG2131	deaminase
ASL18_RS08860	COG2226	methyltransferase
ASL18_RS08865	COG0799	negative regulation of ribosome biogenesis
ASL18_RS08870	COG1713	HD superfamily hydrolase involved in NAD metabolism
ASL18_RS08880	COG1534	Rna-binding protein
ASL18_RS08890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ASL18_RS08895	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ASL18_RS08925	COG3177	Filamentation induced by cAMP protein fic
ASL18_RS08930	COG1914	H( )-stimulated, divalent metal cation uptake system
ASL18_RS08940	COG0439	Biotin carboxylase
ASL18_RS08945	COG0511	ligase activity, forming carbon-carbon bonds
ASL18_RS08950	COG1984	allophanate hydrolase subunit 2
ASL18_RS08955	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ASL18_RS08970	COG0826	peptidase U32
ASL18_RS08975	COG0826	peptidase U32
ASL18_RS09005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASL18_RS09020	COG1104	cysteine desulfurase activity
ASL18_RS09025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASL18_RS09040	COG1959	2 iron, 2 sulfur cluster binding
ASL18_RS09045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASL18_RS09050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASL18_RS09095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASL18_RS09095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ASL18_RS09100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASL18_RS09100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASL18_RS09105	COG1862	Preprotein translocase
ASL18_RS09145	COG2868	ribosomal protein
ASL18_RS09185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASL18_RS09225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASL18_RS09235	COG0285	dihydrofolate synthase activity
ASL18_RS09245	COG2818	Glycosylase
ASL18_RS09280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASL18_RS09315	COG4112	unkown
ASL18_RS09340	COG0833	amino acid
ASL18_RS09355	COG1484	DNA-dependent DNA replication
ASL18_RS09385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASL18_RS09385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASL18_RS09395	COG5002	protein histidine kinase activity
ASL18_RS09400	COG0745	RESPONSE REGULATOR receiver
ASL18_RS09415	COG0372	Belongs to the citrate synthase family
ASL18_RS09420	COG1113	amino acid transport
ASL18_RS09455	COG0281	malic enzyme
ASL18_RS09465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASL18_RS09470	COG4109	DRTGG domain
ASL18_RS09510	COG0827	DNA restriction-modification system
ASL18_RS09530	COG1104	cysteine desulfurase activity
ASL18_RS09545	COG1956	GAF domain-containing protein
ASL18_RS09560	COG0584	glycerophosphoryl diester phosphodiesterase
ASL18_RS09565	COG1764	response to oxidative stress
ASL18_RS09570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASL18_RS09575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASL18_RS09590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASL18_RS09590	COG1263	PTS System
ASL18_RS09595	COG0204	Acyl-transferase
ASL18_RS09600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASL18_RS09635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASL18_RS09640	COG0454	-acetyltransferase
ASL18_RS09660	COG1605	Chorismate mutase
ASL18_RS09660	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ASL18_RS09685	COG1674	ftsk spoiiie
ASL18_RS09690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASL18_RS09700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASL18_RS09705	COG1363	Peptidase, m42
ASL18_RS09715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASL18_RS09725	COG0510	thiamine kinase activity
ASL18_RS09745	COG1187	pseudouridine synthase activity
ASL18_RS09750	COG2244	polysaccharide biosynthetic process
ASL18_RS09755	COG2081	HI0933 family
ASL18_RS09775	COG2814	Major facilitator Superfamily
ASL18_RS09780	COG1242	4 iron, 4 sulfur cluster binding
ASL18_RS09785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ASL18_RS09810	COG2267	carboxylic ester hydrolase activity
ASL18_RS09840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASL18_RS09840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASL18_RS09865	COG3266	domain, Protein
ASL18_RS09865	COG4193	domain, Protein
ASL18_RS09865	COG5632	N-Acetylmuramoyl-L-alanine amidase
ASL18_RS09895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASL18_RS09925	COG0656	L-ascorbic acid biosynthetic process
ASL18_RS09950	COG1506	peptidase
ASL18_RS10130	COG1131	(ABC) transporter
ASL18_RS10235	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ASL18_RS10265	COG1131	(ABC) transporter
ASL18_RS10270	COG0537	adenosine 5'-monophosphoramidase activity
ASL18_RS10300	COG0420	3'-5' exonuclease activity
ASL18_RS10325	COG2197	response regulator
ASL18_RS10330	COG2203	Gaf domain
ASL18_RS10330	COG4585	Histidine kinase
ASL18_RS10335	COG0564	pseudouridine synthase activity
ASL18_RS10370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASL18_RS10375	COG1126	abc transporter atp-binding protein
ASL18_RS10380	COG0765	amino acid transport
ASL18_RS10540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASL18_RS10545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASL18_RS10555	COG4129	membrane
ASL18_RS10580	COG1988	membrane-bound metal-dependent
ASL18_RS10595	COG1388	LysM domain
ASL18_RS10595	COG1134	teichoic acid transport
ASL18_RS10625	COG0535	radical SAM domain protein
ASL18_RS10630	COG1607	acyl-coa hydrolase
ASL18_RS10635	COG2309	aminopeptidase activity
ASL18_RS10655	COG1295	ribonuclease BN
ASL18_RS10660	COG2197	response regulator
ASL18_RS10775	COG4851	CamS sex pheromone cAM373 precursor
ASL18_RS10785	COG0210	DNA helicase
ASL18_RS10795	COG4496	protein, YerC YecD
ASL18_RS10830	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASL18_RS10840	COG0077	Prephenate dehydratase
ASL18_RS10850	COG0471	metal ion transport
ASL18_RS10860	COG1335	isochorismatase
ASL18_RS10875	COG1012	belongs to the aldehyde dehydrogenase family
ASL18_RS10925	COG1131	(ABC) transporter
ASL18_RS10940	COG1725	Transcriptional regulator
ASL18_RS10995	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASL18_RS10995	COG1388	LysM domain
ASL18_RS11005	COG5632	N-Acetylmuramoyl-L-alanine amidase
ASL18_RS11005	COG1388	LysM domain
ASL18_RS11045	COG0739	heme binding
ASL18_RS11090	COG0740	serine-type endopeptidase activity
ASL18_RS11280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASL18_RS11340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASL18_RS11355	COG5484	DNA packaging
ASL18_RS11355	COG3728	DNA packaging
ASL18_RS11430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASL18_RS11435	COG1621	beta-fructofuranosidase activity
ASL18_RS11440	COG1609	Transcriptional regulator
ASL18_RS11445	COG0004	ammonium transporteR
ASL18_RS11450	COG0425	Belongs to the sulfur carrier protein TusA family
ASL18_RS11455	COG2391	methyltransferase activity
ASL18_RS11460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASL18_RS11500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASL18_RS11510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASL18_RS11510	COG1372	Participates in initiation and elongation during chromosome replication
ASL18_RS11520	COG1780	Probably involved in ribonucleotide reductase function
ASL18_RS11555	COG0270	DNA (cytosine-5-)-methyltransferase activity
ASL18_RS11560	COG2226	methyltransferase
ASL18_RS11620	COG0587	DNA-directed DNA polymerase activity
ASL18_RS11625	COG0587	DNA-directed DNA polymerase activity
ASL18_RS11655	COG0456	acetyltransferase
ASL18_RS11685	COG0456	acetyltransferase
ASL18_RS11705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASL18_RS11750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASL18_RS11895	COG2887	Belongs to the helicase family. UvrD subfamily
ASL18_RS12010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASL18_RS12040	COG4373	Mu-like prophage FluMu protein gp28
ASL18_RS12110	COG0582	viral genome integration into host DNA
ASL18_RS12125	COG2433	Pfam Transposase IS66
ASL18_RS12165	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASL18_RS12165	COG1388	LysM domain
ASL18_RS12185	COG2391	methyltransferase activity
ASL18_RS12195	COG0488	(ABC) transporter
ASL18_RS12205	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASL18_RS12215	COG0456	acetyltransferase
ASL18_RS12220	COG1214	PFAM Peptidase M22, glycoprotease
ASL18_RS12225	COG0802	atpase or kinase
ASL18_RS12240	COG0028	Belongs to the TPP enzyme family
ASL18_RS12315	COG2183	response to ionizing radiation
ASL18_RS12320	COG1191	sigma factor activity
ASL18_RS12330	COG1366	Belongs to the anti-sigma-factor antagonist family
ASL18_RS12335	COG2208	phosphoserine phosphatase activity
ASL18_RS12370	COG3428	Bacterial PH domain
ASL18_RS12400	COG2205	protein histidine kinase activity
ASL18_RS12405	COG0745	RESPONSE REGULATOR receiver
ASL18_RS12415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASL18_RS12425	COG0772	Belongs to the SEDS family
ASL18_RS12440	COG1937	Protein conserved in bacteria
ASL18_RS12450	COG1418	mRNA catabolic process
ASL18_RS12495	COG0629	single-stranded DNA binding
ASL18_RS12570	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASL18_RS12595	COG0009	L-threonylcarbamoyladenylate synthase
ASL18_RS12600	COG2890	protein-(glutamine-N5) methyltransferase activity
ASL18_RS12620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASL18_RS12660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASL18_RS12715	COG0813	purine-nucleoside phosphorylase activity
ASL18_RS12720	COG0783	Belongs to the Dps family
ASL18_RS12740	COG1482	cell wall glycoprotein biosynthetic process
ASL18_RS12745	COG0702	epimerase
ASL18_RS12750	COG0640	Transcriptional regulator
ASL18_RS12785	COG0561	phosphatase activity
ASL18_RS12790	COG1119	ATPase activity
ASL18_RS12805	COG3711	transcriptional antiterminator
ASL18_RS12835	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ASL18_RS12905	COG0489	protein tyrosine kinase activity
ASL18_RS12910	COG2814	Major facilitator Superfamily
ASL18_RS12925	COG1272	protein, Hemolysin III
ASL18_RS12935	COG1988	membrane-bound metal-dependent
ASL18_RS12945	COG3314	Sporulation integral membrane protein YlbJ
ASL18_RS12950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASL18_RS12955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASL18_RS12960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ASL18_RS12970	COG3457	Alanine racemase
ASL18_RS12975	COG4264	IucA IucC family
ASL18_RS12980	COG2814	Major facilitator Superfamily
ASL18_RS13020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASL18_RS13030	COG2130	NADP-dependent
ASL18_RS13080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASL18_RS13105	COG0656	L-ascorbic acid biosynthetic process
ASL18_RS13110	COG0789	Transcriptional regulator
ASL18_RS13120	COG5492	domain, Protein
ASL18_RS13140	COG3527	Alpha-acetolactate decarboxylase
ASL18_RS13145	COG0028	Belongs to the TPP enzyme family
ASL18_RS13165	COG0542	response to heat
ASL18_RS13255	COG0201	protein transport
ASL18_RS13375	COG2252	PERMEase
ASL18_RS13420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASL18_RS13490	COG1763	Mo-molybdopterin cofactor biosynthetic process
ASL18_RS13510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASL18_RS13515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASL18_RS13520	COG4149	molybdate abc transporter
ASL18_RS13525	COG0725	ABC transporter, periplasmic molybdate-binding protein
ASL18_RS13540	COG1268	BioY protein
ASL18_RS13555	COG1960	acyl-CoA dehydrogenase activity
ASL18_RS13560	COG4413	Urea transporter
ASL18_RS13625	COG3942	CHAP domain
ASL18_RS13635	COG1757	Na H antiporter
ASL18_RS13650	COG3942	CHAP domain
ASL18_RS13725	COG1113	amino acid transport
ASL18_RS13745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASL18_RS13750	COG0385	Bile acid
ASL18_RS13760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASL18_RS13760	COG1263	PTS System
ASL18_RS13765	COG1737	Transcriptional regulator
ASL18_RS13785	COG1028	Short-chain dehydrogenase reductase Sdr
ASL18_RS13790	COG1473	amidohydrolase
ASL18_RS13805	COG0583	DNA-binding transcription factor activity
ASL18_RS13830	COG2258	MOSC domain
ASL18_RS13850	COG1668	transmembrane transport
ASL18_RS13855	COG4152	abc transporter atp-binding protein
ASL18_RS13860	COG3152	Membrane
ASL18_RS13870	COG0786	glutamate:sodium symporter activity
ASL18_RS13880	COG0598	Magnesium transport protein CorA
ASL18_RS13895	COG0657	acetylesterase activity
ASL18_RS13905	COG2814	Major facilitator Superfamily
ASL18_RS13910	COG1566	PFAM secretion protein HlyD family protein
ASL18_RS13920	COG2814	Major facilitator Superfamily
ASL18_RS13990	COG1620	l-lactate permease
ASL18_RS14010	COG0604	alcohol dehydrogenase
ASL18_RS14015	COG0456	acetyltransferase
ASL18_RS14040	COG1511	domain protein
ASL18_RS14055	COG1263	PTS System
ASL18_RS14055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASL18_RS14070	COG3871	stress protein (general stress protein 26)
ASL18_RS14110	COG0789	Transcriptional regulator
ASL18_RS14130	COG2181	nitrate reductase activity
ASL18_RS14140	COG1140	nitrate reductase beta subunit
ASL18_RS14145	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ASL18_RS14155	COG2146	nitrite reductase [NAD(P)H] activity
ASL18_RS14160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASL18_RS14170	COG0454	-acetyltransferase
ASL18_RS14175	COG2116	formate transmembrane transporter activity
ASL18_RS14190	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASL18_RS14190	COG3443	Belongs to the bacterial solute-binding protein 9 family
ASL18_RS14225	COG1126	abc transporter atp-binding protein
ASL18_RS14230	COG0765	amino acid transport
ASL18_RS14235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASL18_RS14240	COG2814	Major facilitator Superfamily
ASL18_RS14260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASL18_RS14305	COG0156	8-amino-7-oxononanoate synthase activity
ASL18_RS14315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASL18_RS14320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASL18_RS14335	COG1132	(ABC) transporter
ASL18_RS14340	COG2375	cellular response to nickel ion
ASL18_RS14340	COG1132	(ABC) transporter
ASL18_RS14360	COG1929	Belongs to the glycerate kinase type-1 family
ASL18_RS14370	COG2814	Major facilitator Superfamily
ASL18_RS14390	COG1113	amino acid transport
ASL18_RS14405	COG0531	amino acid
ASL18_RS14430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASL18_RS14440	COG1174	glycine betaine transport
ASL18_RS14450	COG1174	glycine betaine transport
ASL18_RS14470	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ASL18_RS14475	COG0531	amino acid
ASL18_RS14480	COG2272	Belongs to the type-B carboxylesterase lipase family
ASL18_RS14485	COG2814	Major facilitator Superfamily
ASL18_RS14490	COG0390	transport system, permease component
ASL18_RS14495	COG4619	ABC transporter
ASL18_RS14500	COG1363	Peptidase, m42
ASL18_RS14520	COG4808	Protein conserved in bacteria
ASL18_RS14525	COG0069	glutamate synthase activity
ASL18_RS14540	COG1124	(ABC) transporter
ASL18_RS14545	COG0444	Belongs to the ABC transporter superfamily
ASL18_RS14550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASL18_RS14555	COG0601	transmembrane transport
ASL18_RS14560	COG0747	negative chemotaxis
ASL18_RS14590	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASL18_RS14595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASL18_RS14645	COG0494	nUDIX hydrolase
ASL18_RS14690	COG1846	Transcriptional regulator
ASL18_RS14695	COG1846	Transcriptional regulator
ASL18_RS14730	COG1070	Carbohydrate kinase
ASL18_RS14735	COG1802	Transcriptional regulator
ASL18_RS14740	COG0789	Transcriptional regulator
ASL18_RS14745	COG2357	RelA SpoT domain protein
ASL18_RS14750	COG4876	unkown
ASL18_RS14760	COG2271	Major facilitator Superfamily
ASL18_RS14765	COG0586	Pfam SNARE associated Golgi protein
ASL18_RS14775	COG2814	Major facilitator Superfamily
ASL18_RS14780	COG1846	Transcriptional regulator
ASL18_RS14785	COG1131	(ABC) transporter
ASL18_RS14805	COG3949	Membrane
ASL18_RS14810	COG0400	carboxylic ester hydrolase activity
ASL18_RS14815	COG0346	lactoylglutathione lyase activity
ASL18_RS14820	COG1846	Transcriptional regulator
ASL18_RS14830	COG2514	catechol 2,3-dioxygenase activity
ASL18_RS14845	COG0561	phosphatase activity
ASL18_RS14850	COG1131	(ABC) transporter
ASL18_RS14860	COG3764	Sortase (surface protein transpeptidase)
ASL18_RS14880	COG1760	l-serine dehydratase
ASL18_RS14885	COG1760	l-serine dehydratase
ASL18_RS14900	COG0697	spore germination
ASL18_RS14905	COG0657	acetylesterase activity
ASL18_RS14925	COG0028	Belongs to the TPP enzyme family
ASL18_RS14940	COG0583	DNA-binding transcription factor activity
ASL18_RS14950	COG3942	CHAP domain
ASL18_RS14975	COG3425	synthase
ASL18_RS14980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASL18_RS14985	COG0542	response to heat
ASL18_RS15005	COG2409	Drug exporters of the RND superfamily
ASL18_RS15050	COG0436	Aminotransferase
ASL18_RS15170	COG2826	transposase and inactivated derivatives, IS30 family
ASL18_RS15190	COG3682	Transcriptional regulator
ASL18_RS15230	COG1674	ftsk spoiiie
ASL18_RS15235	COG0433	COG0433 Predicted ATPase
ASL18_RS15255	COG2946	Replication initiation factor
ASL18_RS15290	COG3001	Fructosamine kinase
ASL18_RS15295	COG0167	dihydroorotate dehydrogenase activity
ASL18_RS15350	COG3527	Alpha-acetolactate decarboxylase
ASL18_RS15365	COG0531	amino acid
ASL18_RS15395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASL18_RS15415	COG1012	belongs to the aldehyde dehydrogenase family
ASL18_RS15425	COG1510	regulation of RNA biosynthetic process
ASL18_RS15430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASL18_RS15455	COG2851	Citrate transporter
ASL18_RS15470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASL18_RS15480	COG0386	Belongs to the glutathione peroxidase family
ASL18_RS15505	COG1136	(ABC) transporter
ASL18_RS15510	COG2205	protein histidine kinase activity
ASL18_RS15515	COG0745	RESPONSE REGULATOR receiver
ASL18_RS15530	COG1785	Belongs to the alkaline phosphatase family
ASL18_RS15535	COG1846	Transcriptional regulator
ASL18_RS15580	COG1438	arginine binding
ASL18_RS15600	COG3711	transcriptional antiterminator
ASL18_RS15600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASL18_RS15605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASL18_RS15605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASL18_RS15605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASL18_RS15610	COG1482	cell wall glycoprotein biosynthetic process
ASL18_RS15620	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASL18_RS15620	COG3942	CHAP domain
ASL18_RS15625	COG3433	isochorismatase activity
ASL18_RS15625	COG1535	isochorismatase
ASL18_RS15640	COG0438	transferase activity, transferring glycosyl groups
ASL18_RS15655	COG1073	alpha beta
ASL18_RS15675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASL18_RS15700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASL18_RS15790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASL18_RS15870	COG0471	metal ion transport
ASL18_RS15875	COG2962	Rard protein
ASL18_RS15885	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ASL18_RS15900	COG1136	(ABC) transporter
ASL18_RS15905	COG0577	efflux transmembrane transporter activity
ASL18_RS15930	COG1404	Belongs to the peptidase S8 family
ASL18_RS15935	COG1278	Cold shock
ASL18_RS15960	COG1475	DNA binding