locus-tag	class	description
MKI61_RS00015	COG2501	S4 domain
MKI61_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MKI61_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKI61_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MKI61_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
MKI61_RS00110	COG4863	YycH protein
MKI61_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MKI61_RS00125	COG0737	Belongs to the 5'-nucleotidase family
MKI61_RS00150	COG3425	synthase
MKI61_RS00155	COG0584	glycerophosphoryl diester phosphodiesterase
MKI61_RS00160	COG2030	dehydratase
MKI61_RS00230	COG3732	PTS system glucitol sorbitol-specific
MKI61_RS00235	COG3730	PTS system glucitol sorbitol-specific
MKI61_RS00300	COG0730	response to heat
MKI61_RS00305	COG1937	Protein conserved in bacteria
MKI61_RS00310	COG2210	Belongs to the sulfur carrier protein TusA family
MKI61_RS00315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKI61_RS00355	COG0823	Involved in the tonB-independent uptake of proteins
MKI61_RS00390	COG1473	amidohydrolase
MKI61_RS00400	COG1283	sodium-dependent phosphate transmembrane transporter activity
MKI61_RS00405	COG4716	Myosin-crossreactive antigen
MKI61_RS00410	COG0697	spore germination
MKI61_RS00425	COG1620	l-lactate permease
MKI61_RS00440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI61_RS00445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI61_RS00450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKI61_RS00460	COG2423	ornithine cyclodeaminase activity
MKI61_RS00465	COG4264	IucA IucC family
MKI61_RS00470	COG2814	Major facilitator Superfamily
MKI61_RS00475	COG4264	IucA IucC family
MKI61_RS00480	COG4264	IucA IucC family
MKI61_RS00490	COG0019	diaminopimelate decarboxylase activity
MKI61_RS00495	COG1475	DNA binding
MKI61_RS00515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKI61_RS00520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MKI61_RS00525	COG0438	transferase activity, transferring glycosyl groups
MKI61_RS00560	COG0813	purine-nucleoside phosphorylase activity
MKI61_RS00565	COG2814	Major facilitator Superfamily
MKI61_RS00585	COG3639	organic phosphonate transmembrane transporter activity
MKI61_RS00605	COG0737	Belongs to the 5'-nucleotidase family
MKI61_RS00620	COG1454	alcohol dehydrogenase
MKI61_RS00620	COG1012	belongs to the aldehyde dehydrogenase family
MKI61_RS00645	COG1086	Polysaccharide biosynthesis protein
MKI61_RS00655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MKI61_RS00685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MKI61_RS00695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MKI61_RS00700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MKI61_RS00710	COG2832	Protein of unknown function (DUF454)
MKI61_RS00745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MKI61_RS00750	COG1960	acyl-CoA dehydrogenase activity
MKI61_RS00755	COG5609	conserved protein (DUF2294)
MKI61_RS00805	COG1114	Component of the transport system for branched-chain amino acids
MKI61_RS00810	COG1335	isochorismatase
MKI61_RS00815	COG3961	Belongs to the TPP enzyme family
MKI61_RS00845	COG1737	Transcriptional regulator
MKI61_RS00870	COG1136	(ABC) transporter
MKI61_RS00875	COG1136	(ABC) transporter
MKI61_RS00875	COG0577	efflux transmembrane transporter activity
MKI61_RS00895	COG1131	(ABC) transporter
MKI61_RS00915	COG0601	transmembrane transport
MKI61_RS00920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKI61_RS00930	COG0405	Gamma-glutamyltransferase
MKI61_RS00950	COG3842	ATPase activity
MKI61_RS00960	COG1175	transmembrane transport
MKI61_RS00965	COG3833	ABC-type maltose transport systems, permease component
MKI61_RS00970	COG0673	inositol 2-dehydrogenase activity
MKI61_RS00975	COG0673	inositol 2-dehydrogenase activity
MKI61_RS00985	COG1755	Isoprenylcysteine carboxyl methyltransferase
MKI61_RS01040	COG0183	Belongs to the thiolase family
MKI61_RS01050	COG1960	acyl-CoA dehydrogenase activity
MKI61_RS01055	COG0318	PFAM AMP-dependent synthetase and ligase
MKI61_RS01070	COG0747	negative chemotaxis
MKI61_RS01075	COG3189	MarR family transcriptional regulator
MKI61_RS01100	COG1263	PTS System
MKI61_RS01100	COG2190	(PTS) system
MKI61_RS01100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI61_RS01105	COG1957	nucleoside hydrolase
MKI61_RS01125	COG3414	Phosphotransferase system galactitol-specific IIB component
MKI61_RS01130	COG3775	system Galactitol-specific IIC component
MKI61_RS01135	COG1063	alcohol dehydrogenase
MKI61_RS01145	COG1063	alcohol dehydrogenase
MKI61_RS01155	COG1063	alcohol dehydrogenase
MKI61_RS01160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKI61_RS01165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKI61_RS01175	COG1063	alcohol dehydrogenase
MKI61_RS01180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKI61_RS01215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKI61_RS01220	COG2190	(PTS) system
MKI61_RS01220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI61_RS01220	COG1263	PTS System
MKI61_RS01225	COG2723	6-phospho-beta-galactosidase activity
MKI61_RS01230	COG2226	methyltransferase
MKI61_RS01285	COG1131	(ABC) transporter
MKI61_RS01305	COG1388	LysM domain
MKI61_RS01305	COG3942	CHAP domain
MKI61_RS01425	COG1114	Component of the transport system for branched-chain amino acids
MKI61_RS01430	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MKI61_RS01435	COG0577	efflux transmembrane transporter activity
MKI61_RS01465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKI61_RS01470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKI61_RS01495	COG3314	Sporulation integral membrane protein YlbJ
MKI61_RS01520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKI61_RS01550	COG3037	sugar-specific permease SgaT UlaA
MKI61_RS01560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKI61_RS01565	COG3711	transcriptional antiterminator
MKI61_RS01585	COG2271	Major facilitator Superfamily
MKI61_RS01590	COG0346	lactoylglutathione lyase activity
MKI61_RS01595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKI61_RS01600	COG0431	NADPH-dependent FMN reductase
MKI61_RS01610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKI61_RS01615	COG2822	iron ion transport
MKI61_RS01625	COG0672	)-iron permease
MKI61_RS01630	COG0805	protein transport
MKI61_RS01635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKI61_RS01645	COG1476	TRANSCRIPTIONal
MKI61_RS01685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MKI61_RS01685	COG0646	methionine synthase
MKI61_RS01690	COG0626	cystathionine gamma-synthase activity
MKI61_RS01695	COG0626	cystathionine gamma-synthase activity
MKI61_RS01700	COG1475	DNA binding
MKI61_RS01705	COG0668	transmembrane transport
MKI61_RS01710	COG4481	Protein conserved in bacteria
MKI61_RS01715	COG0012	GTP binding
MKI61_RS01825	COG1823	symporter activity
MKI61_RS01855	COG2233	PERMEase
MKI61_RS01890	COG3759	membrane
MKI61_RS02050	COG0523	cobalamin synthesis protein
MKI61_RS02075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MKI61_RS02085	COG5609	conserved protein (DUF2294)
MKI61_RS02100	COG1647	Serine aminopeptidase, S33
MKI61_RS02105	COG0733	neurotransmitter:sodium symporter activity
MKI61_RS02110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MKI61_RS02115	COG0626	cystathionine gamma-synthase activity
MKI61_RS02125	COG2011	ABC-type metal ion transport system permease component
MKI61_RS02130	COG1464	Belongs to the NlpA lipoprotein family
MKI61_RS02165	COG0583	DNA-binding transcription factor activity
MKI61_RS02170	COG0070	glutamate synthase
MKI61_RS02170	COG0069	glutamate synthase activity
MKI61_RS02170	COG0067	glutamate synthase
MKI61_RS02175	COG0493	'glutamate synthase
MKI61_RS02185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI61_RS02185	COG1263	PTS System
MKI61_RS02190	COG0366	Alpha amylase catalytic
MKI61_RS02195	COG2188	Transcriptional regulator
MKI61_RS02215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKI61_RS02250	COG1982	Orn Lys Arg decarboxylase major
MKI61_RS02260	COG3870	Protein conserved in bacteria
MKI61_RS02265	COG0470	DNA polymerase III
MKI61_RS02270	COG1774	PSP1 C-terminal conserved region
MKI61_RS02280	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MKI61_RS02290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKI61_RS02300	COG0084	hydrolase, TatD family'
MKI61_RS02305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKI61_RS02315	COG4466	Protein conserved in bacteria
MKI61_RS02325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKI61_RS02330	COG0251	oxidation-reduction process
MKI61_RS02370	COG2244	polysaccharide biosynthetic process
MKI61_RS02375	COG3956	TIGRFAM MazG family protein
MKI61_RS02380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MKI61_RS02390	COG1098	S1 RNA binding domain
MKI61_RS02405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKI61_RS02430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKI61_RS02525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKI61_RS02540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKI61_RS02550	COG3880	PFAM UvrB UvrC protein
MKI61_RS02565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKI61_RS02570	COG4956	integral membrane protein (PIN domain superfamily)
MKI61_RS02590	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKI61_RS02645	COG2813	Specifically methylates the guanine in position
MKI61_RS02685	COG1473	amidohydrolase
MKI61_RS02715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MKI61_RS02720	COG1428	Deoxynucleoside kinase
MKI61_RS02725	COG1428	Deoxynucleoside kinase
MKI61_RS02735	COG0561	phosphatase activity
MKI61_RS02775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MKI61_RS02790	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MKI61_RS02880	COG0095	Lipoate-protein ligase
MKI61_RS02885	COG0083	homoserine kinase activity
MKI61_RS02905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKI61_RS02940	COG0667	Aldo Keto reductase
MKI61_RS02945	COG0655	NAD(P)H dehydrogenase (quinone) activity
MKI61_RS02955	COG1078	dGTPase activity
MKI61_RS02990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKI61_RS02995	COG4139	cobalamin transport
MKI61_RS03045	COG4974	Belongs to the 'phage' integrase family
MKI61_RS03100	COG0803	Belongs to the bacterial solute-binding protein 9 family
MKI61_RS03105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKI61_RS03110	COG1121	(ABC) transporter
MKI61_RS03115	COG1321	iron dependent repressor
MKI61_RS03125	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MKI61_RS03135	COG1682	transport, permease protein
MKI61_RS03140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKI61_RS03150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MKI61_RS03155	COG1686	Belongs to the peptidase S11 family
MKI61_RS03160	COG1132	(ABC) transporter
MKI61_RS03165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKI61_RS03175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKI61_RS03180	COG1120	ATPase activity
MKI61_RS03185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI61_RS03190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI61_RS03195	COG2376	Dihydroxyacetone kinase
MKI61_RS03205	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MKI61_RS03215	COG3949	Membrane
MKI61_RS03235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKI61_RS03250	COG1136	(ABC) transporter
MKI61_RS03255	COG0577	efflux transmembrane transporter activity
MKI61_RS03260	COG1392	Phosphate transport regulator
MKI61_RS03265	COG0306	phosphate transporter
MKI61_RS03270	COG1388	LysM domain
MKI61_RS03270	COG3942	CHAP domain
MKI61_RS03280	COG4977	sequence-specific DNA binding
MKI61_RS03280	COG1917	Cupin 2, conserved barrel domain protein
MKI61_RS03310	COG0583	DNA-binding transcription factor activity
MKI61_RS03315	COG2814	Major facilitator Superfamily
MKI61_RS03320	COG2839	Protein conserved in bacteria
MKI61_RS03350	COG1611	Belongs to the LOG family
MKI61_RS03370	COG4988	ABC transporter
MKI61_RS03375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MKI61_RS03385	COG0523	cobalamin synthesis protein
MKI61_RS03390	COG4989	oxidoreductase activity
MKI61_RS03400	COG0471	metal ion transport
MKI61_RS03405	COG0415	Belongs to the DNA photolyase family
MKI61_RS03435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKI61_RS03440	COG1349	DNA-binding transcription factor activity
MKI61_RS03445	COG1105	Belongs to the carbohydrate kinase PfkB family
MKI61_RS03455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKI61_RS03460	COG1253	flavin adenine dinucleotide binding
MKI61_RS03465	COG0656	L-ascorbic acid biosynthetic process
MKI61_RS03470	COG0463	Glycosyl transferase, family 2
MKI61_RS03505	COG0720	synthase
MKI61_RS03515	COG0512	Glutamine amidotransferase of anthranilate synthase
MKI61_RS03515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKI61_RS03520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKI61_RS03550	COG0488	(ABC) transporter
MKI61_RS03555	COG0514	ATP-dependent DNA helicase (RecQ)
MKI61_RS03560	COG0517	IMP dehydrogenase activity
MKI61_RS03560	COG1125	glycine betaine transport
MKI61_RS03565	COG1174	glycine betaine transport
MKI61_RS03590	COG3104	oligopeptide transport
MKI61_RS03615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKI61_RS03620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKI61_RS03630	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI61_RS03635	COG4605	iron ion homeostasis
MKI61_RS03640	COG4604	ABC transporter, ATP-binding protein
MKI61_RS03645	COG4607	ABC-type enterochelin transport system periplasmic component
MKI61_RS03700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKI61_RS03705	COG1739	Uncharacterized protein family UPF0029
MKI61_RS03715	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MKI61_RS03720	COG1040	competence protein
MKI61_RS03750	COG3942	CHAP domain
MKI61_RS03750	COG1388	LysM domain
MKI61_RS03805	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MKI61_RS03865	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MKI61_RS03870	COG1647	Serine aminopeptidase, S33
MKI61_RS03875	COG0557	exoribonuclease II activity
MKI61_RS03975	COG5484	DNA packaging
MKI61_RS03975	COG3728	DNA packaging
MKI61_RS04005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKI61_RS04010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MKI61_RS04070	COG1278	Cold shock
MKI61_RS04110	COG0406	alpha-ribazole phosphatase activity
MKI61_RS04115	COG1279	arginine transmembrane transporter activity
MKI61_RS04140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKI61_RS04145	COG1393	Belongs to the ArsC family
MKI61_RS04155	COG3878	Protein conserved in bacteria
MKI61_RS04160	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKI61_RS04175	COG2011	ABC-type metal ion transport system permease component
MKI61_RS04180	COG1464	Belongs to the NlpA lipoprotein family
MKI61_RS04195	COG0396	ATPase activity
MKI61_RS04200	COG0719	Fe-S assembly protein
MKI61_RS04210	COG0822	iron-sulfur transferase activity
MKI61_RS04230	COG1253	flavin adenine dinucleotide binding
MKI61_RS04245	COG1801	Protein of unknown function DUF72
MKI61_RS04250	COG0730	response to heat
MKI61_RS04265	COG4470	Protein conserved in bacteria
MKI61_RS04285	COG2445	Protein of unknown function DUF86
MKI61_RS04315	COG1696	Membrane protein involved in D-alanine export
MKI61_RS04325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKI61_RS04330	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MKI61_RS04335	COG4837	Protein of unknown function (DUF1462)
MKI61_RS04340	COG1252	NADH dehydrogenase
MKI61_RS04350	COG0316	Belongs to the HesB IscA family
MKI61_RS04360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MKI61_RS04365	COG2056	Na+-H+ antiporter family
MKI61_RS04370	COG2050	protein possibly involved in aromatic compounds catabolism
MKI61_RS04425	COG1098	S1 RNA binding domain
MKI61_RS04430	COG1902	pentaerythritol trinitrate reductase activity
MKI61_RS04445	COG0584	glycerophosphoryl diester phosphodiesterase
MKI61_RS04465	COG0398	Pfam SNARE associated Golgi protein
MKI61_RS04505	COG0561	phosphatase activity
MKI61_RS04545	COG1881	PFAM PEBP family protein
MKI61_RS04575	COG0601	transmembrane transport
MKI61_RS04580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKI61_RS04585	COG0444	Belongs to the ABC transporter superfamily
MKI61_RS04590	COG4608	Belongs to the ABC transporter superfamily
MKI61_RS04595	COG4166	transmembrane transport
MKI61_RS04600	COG0747	negative chemotaxis
MKI61_RS04605	COG0444	Belongs to the ABC transporter superfamily
MKI61_RS04610	COG4608	Belongs to the ABC transporter superfamily
MKI61_RS04615	COG0601	transmembrane transport
MKI61_RS04620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKI61_RS04645	COG1164	Oligoendopeptidase f
MKI61_RS04655	COG2346	COG2346, Truncated hemoglobins
MKI61_RS04670	COG2357	RelA SpoT domain protein
MKI61_RS04680	COG0564	pseudouridine synthase activity
MKI61_RS04685	COG2239	Acts as a magnesium transporter
MKI61_RS04690	COG0569	domain protein
MKI61_RS04690	COG0475	glutathione-regulated potassium exporter activity
MKI61_RS04710	COG0628	permease
MKI61_RS04715	COG1115	amino acid carrier protein
MKI61_RS04755	COG0861	Integral membrane protein TerC family
MKI61_RS04775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKI61_RS04780	COG0737	Belongs to the 5'-nucleotidase family
MKI61_RS04795	COG4903	ComK protein
MKI61_RS04810	COG4873	Protein conserved in bacteria
MKI61_RS04865	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MKI61_RS04875	COG2314	TM2 domain
MKI61_RS04880	COG0456	acetyltransferase
MKI61_RS04885	COG1575	Belongs to the MenA family. Type 1 subfamily
MKI61_RS04895	COG1169	isochorismate synthase
MKI61_RS04905	COG2267	carboxylic ester hydrolase activity
MKI61_RS04930	COG0436	Aminotransferase
MKI61_RS04935	COG3594	Acyltransferase
MKI61_RS04965	COG1316	TRANSCRIPTIONal
MKI61_RS05010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKI61_RS05025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKI61_RS05065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKI61_RS05070	COG4172	Belongs to the ABC transporter superfamily
MKI61_RS05075	COG4721	ABC-type cobalt transport system, permease component
MKI61_RS05090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MKI61_RS05110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MKI61_RS05115	COG1271	oxidase subunit
MKI61_RS05120	COG1294	oxidase, subunit
MKI61_RS05125	COG0569	domain protein
MKI61_RS05190	COG1176	ABC-type spermidine putrescine transport system, permease component I
MKI61_RS05195	COG1177	transmembrane transport
MKI61_RS05200	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MKI61_RS05225	COG0483	inositol monophosphate 1-phosphatase activity
MKI61_RS05235	COG1217	gtp-binding protein TYPA
MKI61_RS05245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKI61_RS05255	COG0772	Belongs to the SEDS family
MKI61_RS05285	COG3679	Belongs to the UPF0342 family
MKI61_RS05305	COG0742	ribosomal rna small subunit methyltransferase
MKI61_RS05360	COG4509	Sortase family
MKI61_RS05375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKI61_RS05405	COG1796	DNA polymerase
MKI61_RS05405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MKI61_RS05430	COG2009	succinate dehydrogenase
MKI61_RS05435	COG1053	succinate dehydrogenase
MKI61_RS05440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MKI61_RS05555	COG1288	antiporter activity
MKI61_RS05590	COG1011	Hydrolase
MKI61_RS05615	COG4839	cell division protein FtsL
MKI61_RS05620	COG0768	penicillin binding
MKI61_RS05635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MKI61_RS05640	COG0849	cell division
MKI61_RS05655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKI61_RS05665	COG0762	integral membrane protein
MKI61_RS05670	COG2302	S4 RNA-binding domain
MKI61_RS05675	COG3599	regulation of cell shape
MKI61_RS05685	COG2514	catechol 2,3-dioxygenase activity
MKI61_RS05700	COG0564	pseudouridine synthase activity
MKI61_RS05710	COG2233	PERMEase
MKI61_RS05755	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MKI61_RS05770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKI61_RS05775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKI61_RS05785	COG2314	TM2 domain
MKI61_RS05800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKI61_RS05800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKI61_RS05810	COG0631	protein serine/threonine phosphatase activity
MKI61_RS05825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MKI61_RS05840	COG1302	Protein conserved in bacteria
MKI61_RS05885	COG1196	nuclear chromosome segregation
MKI61_RS05890	COG0552	protein localization to endoplasmic reticulum
MKI61_RS05900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKI61_RS05960	COG0758	DNA mediated transformation
MKI61_RS06055	COG0195	Participates in both transcription termination and antitermination
MKI61_RS06060	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MKI61_RS06085	COG0196	riboflavin kinase activity
MKI61_RS06110	COG2188	Transcriptional regulator
MKI61_RS06115	COG0612	Peptidase, M16
MKI61_RS06120	COG0612	Peptidase, M16
MKI61_RS06125	COG0300	oxidoreductase activity
MKI61_RS06145	COG1058	Belongs to the CinA family
MKI61_RS06145	COG1546	Belongs to the CinA family
MKI61_RS06165	COG1692	metallophosphoesterase
MKI61_RS06170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MKI61_RS06170	COG0674	pyruvate-flavodoxin oxidoreductase activity
MKI61_RS06175	COG1013	pyruvate-flavodoxin oxidoreductase activity
MKI61_RS06210	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKI61_RS06215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MKI61_RS06240	COG1923	regulation of RNA biosynthetic process
MKI61_RS06250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKI61_RS06255	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MKI61_RS06260	COG0789	Transcriptional regulator
MKI61_RS06330	COG1131	(ABC) transporter
MKI61_RS06345	COG2197	response regulator
MKI61_RS06355	COG1525	nuclease
MKI61_RS06370	COG0527	aspartate kinase activity
MKI61_RS06375	COG0460	homoserine dehydrogenase
MKI61_RS06380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKI61_RS06405	COG0833	amino acid
MKI61_RS06435	COG2340	Cysteine-rich secretory protein family
MKI61_RS06470	COG4846	Membrane protein involved in cytochrome C biogenesis
MKI61_RS06490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKI61_RS06500	COG0824	Thioesterase
MKI61_RS06525	COG1115	amino acid carrier protein
MKI61_RS06540	COG0628	permease
MKI61_RS06565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKI61_RS06575	COG1363	Peptidase, m42
MKI61_RS06580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKI61_RS06585	COG0512	Glutamine amidotransferase of anthranilate synthase
MKI61_RS06630	COG0561	phosphatase activity
MKI61_RS06675	COG0704	Plays a role in the regulation of phosphate uptake
MKI61_RS06685	COG0581	inorganic phosphate transmembrane transporter activity
MKI61_RS06690	COG0573	inorganic phosphate transmembrane transporter activity
MKI61_RS06710	COG0488	(ABC) transporter
MKI61_RS06715	COG0527	aspartate kinase activity
MKI61_RS06720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKI61_RS06790	COG4548	von Willebrand factor, type A
MKI61_RS06795	COG0714	Associated with various cellular activities
MKI61_RS06840	COG0671	phosphoesterase, PA-phosphatase related
MKI61_RS06915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKI61_RS06935	COG0531	amino acid
MKI61_RS06950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKI61_RS06955	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKI61_RS06970	COG0116	Belongs to the methyltransferase superfamily
MKI61_RS07005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MKI61_RS07005	COG4499	WXG100 protein secretion system (Wss), protein YukC
MKI61_RS07015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKI61_RS07020	COG3935	DnaD domain protein
MKI61_RS07045	COG0438	transferase activity, transferring glycosyl groups
MKI61_RS07050	COG1694	Mazg nucleotide pyrophosphohydrolase
MKI61_RS07055	COG2738	Putative neutral zinc metallopeptidase
MKI61_RS07060	COG4347	Protein of unknown function (DUF1405)
MKI61_RS07100	COG0142	geranyltranstransferase activity
MKI61_RS07155	COG0492	ferredoxin-NADP+ reductase activity
MKI61_RS07170	COG0514	ATP-dependent DNA helicase (RecQ)
MKI61_RS07180	COG1141	Ferredoxin
MKI61_RS07225	COG0745	RESPONSE REGULATOR receiver
MKI61_RS07230	COG1187	pseudouridine synthase activity
MKI61_RS07255	COG0735	belongs to the Fur family
MKI61_RS07260	COG0494	nUDIX hydrolase
MKI61_RS07265	COG0667	Aldo Keto reductase
MKI61_RS07275	COG4221	oxidoreductase activity
MKI61_RS07290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKI61_RS07300	COG0366	Alpha amylase catalytic
MKI61_RS07305	COG1609	Transcriptional regulator
MKI61_RS07330	COG2195	Cleaves the N-terminal amino acid of tripeptides
MKI61_RS07340	COG4129	membrane
MKI61_RS07350	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKI61_RS07355	COG0022	dehydrogenase e1 component
MKI61_RS07360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MKI61_RS07365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKI61_RS07370	COG0497	DNA recombination
MKI61_RS07400	COG1302	Protein conserved in bacteria
MKI61_RS07405	COG0439	Biotin carboxylase
MKI61_RS07410	COG0511	ligase activity, forming carbon-carbon bonds
MKI61_RS07420	COG0006	proline dipeptidase activity
MKI61_RS07435	COG0095	Lipoate-protein ligase
MKI61_RS07440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKI61_RS07485	COG4537	Required for transformation and DNA binding
MKI61_RS07490	COG1459	type II secretion system
MKI61_RS07495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKI61_RS07500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKI61_RS07505	COG0011	TIGRFAM Protein of
MKI61_RS07510	COG1940	carbohydrate kinase activity
MKI61_RS07515	COG4483	Protein conserved in bacteria
MKI61_RS07525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKI61_RS07535	COG0768	penicillin binding
MKI61_RS07550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKI61_RS07555	COG1121	(ABC) transporter
MKI61_RS07565	COG0513	Belongs to the DEAD box helicase family
MKI61_RS07575	COG2384	SAM-dependent methyltransferase
MKI61_RS07595	COG0517	IMP dehydrogenase activity
MKI61_RS07615	COG0295	cytidine deaminase activity
MKI61_RS07630	COG1702	phosphate starvation-inducible protein PhoH
MKI61_RS07645	COG1030	water channel activity
MKI61_RS07655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKI61_RS07660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MKI61_RS07690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MKI61_RS07705	COG1466	dna polymerase III delta subunit
MKI61_RS07710	COG2333	competence protein COMEC
MKI61_RS07710	COG0658	competence protein
MKI61_RS07715	COG2131	deaminase
MKI61_RS07720	COG2183	response to ionizing radiation
MKI61_RS07725	COG2226	methyltransferase
MKI61_RS07730	COG0799	negative regulation of ribosome biogenesis
MKI61_RS07735	COG1713	HD superfamily hydrolase involved in NAD metabolism
MKI61_RS07745	COG1534	Rna-binding protein
MKI61_RS07755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKI61_RS07760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MKI61_RS07780	COG3177	Filamentation induced by cAMP protein fic
MKI61_RS07785	COG1914	H( )-stimulated, divalent metal cation uptake system
MKI61_RS07795	COG0439	Biotin carboxylase
MKI61_RS07800	COG0511	ligase activity, forming carbon-carbon bonds
MKI61_RS07805	COG1984	allophanate hydrolase subunit 2
MKI61_RS07810	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MKI61_RS07825	COG0826	peptidase U32
MKI61_RS07830	COG0826	peptidase U32
MKI61_RS07860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MKI61_RS07875	COG1104	cysteine desulfurase activity
MKI61_RS07880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKI61_RS07890	COG3237	CsbD-like
MKI61_RS07895	COG1959	2 iron, 2 sulfur cluster binding
MKI61_RS07900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MKI61_RS07905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MKI61_RS07950	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MKI61_RS07950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MKI61_RS07955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKI61_RS07955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKI61_RS07960	COG1862	Preprotein translocase
MKI61_RS08000	COG2868	ribosomal protein
MKI61_RS08045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MKI61_RS08050	COG0285	dihydrofolate synthase activity
MKI61_RS08060	COG2818	Glycosylase
MKI61_RS08095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MKI61_RS08130	COG4112	unkown
MKI61_RS08150	COG0833	amino acid
MKI61_RS08165	COG1484	DNA-dependent DNA replication
MKI61_RS08195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKI61_RS08195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKI61_RS08205	COG5002	protein histidine kinase activity
MKI61_RS08210	COG0745	RESPONSE REGULATOR receiver
MKI61_RS08220	COG0372	Belongs to the citrate synthase family
MKI61_RS08225	COG1113	amino acid transport
MKI61_RS08250	COG0281	malic enzyme
MKI61_RS08260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MKI61_RS08265	COG4109	DRTGG domain
MKI61_RS08305	COG0827	DNA restriction-modification system
MKI61_RS08315	COG0730	response to heat
MKI61_RS08325	COG1104	cysteine desulfurase activity
MKI61_RS08340	COG1956	GAF domain-containing protein
MKI61_RS08350	COG0584	glycerophosphoryl diester phosphodiesterase
MKI61_RS08355	COG1764	response to oxidative stress
MKI61_RS08360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MKI61_RS08365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MKI61_RS08380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI61_RS08380	COG1263	PTS System
MKI61_RS08385	COG0204	Acyl-transferase
MKI61_RS08390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKI61_RS08425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MKI61_RS08430	COG0454	-acetyltransferase
MKI61_RS08450	COG1605	Chorismate mutase
MKI61_RS08450	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MKI61_RS08475	COG1674	ftsk spoiiie
MKI61_RS08480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKI61_RS08490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKI61_RS08495	COG1363	Peptidase, m42
MKI61_RS08505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKI61_RS08515	COG0510	thiamine kinase activity
MKI61_RS08535	COG1187	pseudouridine synthase activity
MKI61_RS08540	COG2244	polysaccharide biosynthetic process
MKI61_RS08545	COG2081	HI0933 family
MKI61_RS08565	COG2814	Major facilitator Superfamily
MKI61_RS08570	COG1242	4 iron, 4 sulfur cluster binding
MKI61_RS08575	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MKI61_RS08585	COG2267	carboxylic ester hydrolase activity
MKI61_RS08615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKI61_RS08615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKI61_RS08635	COG3266	domain, Protein
MKI61_RS08635	COG5632	N-Acetylmuramoyl-L-alanine amidase
MKI61_RS08635	COG4193	domain, Protein
MKI61_RS08665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKI61_RS08690	COG0656	L-ascorbic acid biosynthetic process
MKI61_RS08710	COG1506	peptidase
MKI61_RS08715	COG2816	NAD+ diphosphatase activity
MKI61_RS08960	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MKI61_RS08990	COG1131	(ABC) transporter
MKI61_RS08995	COG0537	adenosine 5'-monophosphoramidase activity
MKI61_RS09025	COG0420	3'-5' exonuclease activity
MKI61_RS09050	COG2197	response regulator
MKI61_RS09055	COG2203	Gaf domain
MKI61_RS09055	COG4585	Histidine kinase
MKI61_RS09060	COG0564	pseudouridine synthase activity
MKI61_RS09090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKI61_RS09095	COG1126	abc transporter atp-binding protein
MKI61_RS09100	COG0765	amino acid transport
MKI61_RS09285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MKI61_RS09290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MKI61_RS09300	COG4129	membrane
MKI61_RS09325	COG1988	membrane-bound metal-dependent
MKI61_RS09335	COG1134	teichoic acid transport
MKI61_RS09335	COG1388	LysM domain
MKI61_RS09380	COG1388	LysM domain
MKI61_RS09380	COG5632	N-Acetylmuramoyl-L-alanine amidase
MKI61_RS09590	COG1484	DNA-dependent DNA replication
MKI61_RS09700	COG4974	Belongs to the 'phage' integrase family
MKI61_RS09705	COG0535	radical SAM domain protein
MKI61_RS09710	COG1607	acyl-coa hydrolase
MKI61_RS09715	COG2309	aminopeptidase activity
MKI61_RS09735	COG1295	ribonuclease BN
MKI61_RS09850	COG4851	CamS sex pheromone cAM373 precursor
MKI61_RS09870	COG4496	protein, YerC YecD
MKI61_RS09905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKI61_RS09915	COG0077	Prephenate dehydratase
MKI61_RS09935	COG1335	isochorismatase
MKI61_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
MKI61_RS10005	COG1131	(ABC) transporter
MKI61_RS10020	COG1725	Transcriptional regulator
MKI61_RS10070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKI61_RS10115	COG5484	DNA packaging
MKI61_RS10115	COG3728	DNA packaging
MKI61_RS10200	COG0582	viral genome integration into host DNA
MKI61_RS10265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKI61_RS10270	COG1621	beta-fructofuranosidase activity
MKI61_RS10275	COG1609	Transcriptional regulator
MKI61_RS10280	COG0004	ammonium transporteR
MKI61_RS10285	COG0425	Belongs to the sulfur carrier protein TusA family
MKI61_RS10290	COG2391	methyltransferase activity
MKI61_RS10300	COG0488	(ABC) transporter
MKI61_RS10310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKI61_RS10320	COG0456	acetyltransferase
MKI61_RS10325	COG1214	PFAM Peptidase M22, glycoprotease
MKI61_RS10330	COG0802	atpase or kinase
MKI61_RS10345	COG0028	Belongs to the TPP enzyme family
MKI61_RS10415	COG2183	response to ionizing radiation
MKI61_RS10420	COG1191	sigma factor activity
MKI61_RS10430	COG1366	Belongs to the anti-sigma-factor antagonist family
MKI61_RS10435	COG2208	phosphoserine phosphatase activity
MKI61_RS10465	COG3428	Bacterial PH domain
MKI61_RS10495	COG2205	protein histidine kinase activity
MKI61_RS10500	COG0745	RESPONSE REGULATOR receiver
MKI61_RS10520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MKI61_RS10530	COG0772	Belongs to the SEDS family
MKI61_RS10545	COG1937	Protein conserved in bacteria
MKI61_RS10555	COG1418	mRNA catabolic process
MKI61_RS10590	COG0629	single-stranded DNA binding
MKI61_RS10665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MKI61_RS10690	COG0009	L-threonylcarbamoyladenylate synthase
MKI61_RS10695	COG2890	protein-(glutamine-N5) methyltransferase activity
MKI61_RS10715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKI61_RS10755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKI61_RS10800	COG0813	purine-nucleoside phosphorylase activity
MKI61_RS10805	COG0783	Belongs to the Dps family
MKI61_RS10825	COG1482	cell wall glycoprotein biosynthetic process
MKI61_RS10830	COG0702	epimerase
MKI61_RS10835	COG0640	Transcriptional regulator
MKI61_RS10870	COG0561	phosphatase activity
MKI61_RS10875	COG1119	ATPase activity
MKI61_RS10890	COG3711	transcriptional antiterminator
MKI61_RS10920	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKI61_RS10990	COG0489	protein tyrosine kinase activity
MKI61_RS10995	COG2814	Major facilitator Superfamily
MKI61_RS11010	COG1272	protein, Hemolysin III
MKI61_RS11020	COG1988	membrane-bound metal-dependent
MKI61_RS11030	COG3314	Sporulation integral membrane protein YlbJ
MKI61_RS11035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI61_RS11040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI61_RS11045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MKI61_RS11055	COG3457	Alanine racemase
MKI61_RS11060	COG4264	IucA IucC family
MKI61_RS11065	COG2814	Major facilitator Superfamily
MKI61_RS11090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKI61_RS11100	COG2130	NADP-dependent
MKI61_RS11165	COG0656	L-ascorbic acid biosynthetic process
MKI61_RS11170	COG0789	Transcriptional regulator
MKI61_RS11180	COG5492	domain, Protein
MKI61_RS11200	COG3527	Alpha-acetolactate decarboxylase
MKI61_RS11205	COG0028	Belongs to the TPP enzyme family
MKI61_RS11325	COG0201	protein transport
MKI61_RS11440	COG2252	PERMEase
MKI61_RS11485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKI61_RS11545	COG1763	Mo-molybdopterin cofactor biosynthetic process
MKI61_RS11565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MKI61_RS11570	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MKI61_RS11575	COG4149	molybdate abc transporter
MKI61_RS11580	COG0725	ABC transporter, periplasmic molybdate-binding protein
MKI61_RS11595	COG1268	BioY protein
MKI61_RS11610	COG1960	acyl-CoA dehydrogenase activity
MKI61_RS11615	COG4413	Urea transporter
MKI61_RS11675	COG3942	CHAP domain
MKI61_RS11685	COG1757	Na H antiporter
MKI61_RS11700	COG3942	CHAP domain
MKI61_RS11765	COG1113	amino acid transport
MKI61_RS11785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MKI61_RS11790	COG0385	Bile acid
MKI61_RS11800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI61_RS11800	COG1263	PTS System
MKI61_RS11805	COG1737	Transcriptional regulator
MKI61_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
MKI61_RS11830	COG1473	amidohydrolase
MKI61_RS11845	COG0583	DNA-binding transcription factor activity
MKI61_RS11870	COG2258	MOSC domain
MKI61_RS11890	COG1668	transmembrane transport
MKI61_RS11900	COG3152	Membrane
MKI61_RS11910	COG0786	glutamate:sodium symporter activity
MKI61_RS11920	COG0598	Magnesium transport protein CorA
MKI61_RS11935	COG0657	acetylesterase activity
MKI61_RS11945	COG2814	Major facilitator Superfamily
MKI61_RS11950	COG1566	PFAM secretion protein HlyD family protein
MKI61_RS11960	COG2814	Major facilitator Superfamily
MKI61_RS12020	COG1620	l-lactate permease
MKI61_RS12040	COG0604	alcohol dehydrogenase
MKI61_RS12065	COG1511	domain protein
MKI61_RS12080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI61_RS12080	COG1263	PTS System
MKI61_RS12095	COG3871	stress protein (general stress protein 26)
MKI61_RS12135	COG0789	Transcriptional regulator
MKI61_RS12155	COG2181	nitrate reductase activity
MKI61_RS12165	COG1140	nitrate reductase beta subunit
MKI61_RS12170	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKI61_RS12180	COG2146	nitrite reductase [NAD(P)H] activity
MKI61_RS12185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKI61_RS12195	COG0454	-acetyltransferase
MKI61_RS12200	COG2116	formate transmembrane transporter activity
MKI61_RS12215	COG3443	Belongs to the bacterial solute-binding protein 9 family
MKI61_RS12215	COG0803	Belongs to the bacterial solute-binding protein 9 family
MKI61_RS12255	COG1126	abc transporter atp-binding protein
MKI61_RS12260	COG0765	amino acid transport
MKI61_RS12265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKI61_RS12270	COG2814	Major facilitator Superfamily
MKI61_RS12285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKI61_RS12325	COG0156	8-amino-7-oxononanoate synthase activity
MKI61_RS12335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MKI61_RS12340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MKI61_RS12350	COG1132	(ABC) transporter
MKI61_RS12355	COG1132	(ABC) transporter
MKI61_RS12355	COG2375	cellular response to nickel ion
MKI61_RS12370	COG1929	Belongs to the glycerate kinase type-1 family
MKI61_RS12380	COG2814	Major facilitator Superfamily
MKI61_RS12400	COG1113	amino acid transport
MKI61_RS12410	COG0531	amino acid
MKI61_RS12425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKI61_RS12435	COG1174	glycine betaine transport
MKI61_RS12445	COG1174	glycine betaine transport
MKI61_RS12465	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MKI61_RS12470	COG0531	amino acid
MKI61_RS12475	COG2272	Belongs to the type-B carboxylesterase lipase family
MKI61_RS12480	COG2814	Major facilitator Superfamily
MKI61_RS12485	COG0390	transport system, permease component
MKI61_RS12490	COG4619	ABC transporter
MKI61_RS12495	COG1363	Peptidase, m42
MKI61_RS12510	COG4808	Protein conserved in bacteria
MKI61_RS12515	COG0069	glutamate synthase activity
MKI61_RS12570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MKI61_RS12575	COG1028	Short-chain dehydrogenase reductase Sdr
MKI61_RS12580	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MKI61_RS12585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKI61_RS12670	COG0494	nUDIX hydrolase
MKI61_RS12710	COG1846	Transcriptional regulator
MKI61_RS12740	COG1070	Carbohydrate kinase
MKI61_RS12745	COG1802	Transcriptional regulator
MKI61_RS12750	COG0789	Transcriptional regulator
MKI61_RS12755	COG2357	RelA SpoT domain protein
MKI61_RS12760	COG4876	unkown
MKI61_RS12770	COG2271	Major facilitator Superfamily
MKI61_RS12775	COG0586	Pfam SNARE associated Golgi protein
MKI61_RS12785	COG1131	(ABC) transporter
MKI61_RS12800	COG3949	Membrane
MKI61_RS12805	COG0400	carboxylic ester hydrolase activity
MKI61_RS12810	COG0346	lactoylglutathione lyase activity
MKI61_RS12815	COG1846	Transcriptional regulator
MKI61_RS12825	COG2514	catechol 2,3-dioxygenase activity
MKI61_RS12840	COG0561	phosphatase activity
MKI61_RS12845	COG1131	(ABC) transporter
MKI61_RS12855	COG3764	Sortase (surface protein transpeptidase)
MKI61_RS12875	COG1760	l-serine dehydratase
MKI61_RS12880	COG1760	l-serine dehydratase
MKI61_RS12895	COG0697	spore germination
MKI61_RS12900	COG0657	acetylesterase activity
MKI61_RS12920	COG0028	Belongs to the TPP enzyme family
MKI61_RS12935	COG0583	DNA-binding transcription factor activity
MKI61_RS12945	COG3942	CHAP domain
MKI61_RS12955	COG3425	synthase
MKI61_RS12960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKI61_RS12985	COG2409	Drug exporters of the RND superfamily
MKI61_RS13040	COG0436	Aminotransferase
MKI61_RS13070	COG3942	CHAP domain
MKI61_RS13075	COG2755	lipolytic protein G-D-S-L family
MKI61_RS13075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MKI61_RS13190	COG0456	acetyltransferase
MKI61_RS13245	COG1279	arginine transmembrane transporter activity
MKI61_RS13265	COG3173	Aminoglycoside phosphotransferase
MKI61_RS13320	COG0456	acetyltransferase
MKI61_RS13330	COG2378	regulation of single-species biofilm formation
MKI61_RS13415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MKI61_RS13420	COG2801	Transposase and inactivated derivatives
MKI61_RS13480	COG0456	acetyltransferase
MKI61_RS13525	COG3409	Peptidoglycan-binding domain 1 protein
MKI61_RS13540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKI61_RS13680	COG4115	mRNA cleavage
MKI61_RS13695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKI61_RS13715	COG1192	Involved in chromosome partitioning
MKI61_RS13765	COG2226	methyltransferase
MKI61_RS13775	COG0456	acetyltransferase
MKI61_RS13845	COG3001	Fructosamine kinase
MKI61_RS13850	COG0167	dihydroorotate dehydrogenase activity
MKI61_RS13905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKI61_RS13910	COG3527	Alpha-acetolactate decarboxylase
MKI61_RS13920	COG0531	amino acid
MKI61_RS13950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MKI61_RS13970	COG1012	belongs to the aldehyde dehydrogenase family
MKI61_RS13980	COG1510	regulation of RNA biosynthetic process
MKI61_RS13985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKI61_RS14010	COG2851	Citrate transporter
MKI61_RS14025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKI61_RS14035	COG0386	Belongs to the glutathione peroxidase family
MKI61_RS14055	COG1136	(ABC) transporter
MKI61_RS14060	COG2205	protein histidine kinase activity
MKI61_RS14065	COG0745	RESPONSE REGULATOR receiver
MKI61_RS14075	COG1785	Belongs to the alkaline phosphatase family
MKI61_RS14085	COG1846	Transcriptional regulator
MKI61_RS14130	COG1438	arginine binding
MKI61_RS14150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKI61_RS14150	COG3711	transcriptional antiterminator
MKI61_RS14155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKI61_RS14155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKI61_RS14155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKI61_RS14160	COG1482	cell wall glycoprotein biosynthetic process
MKI61_RS14170	COG1705	Flagellar rod assembly protein muramidase FlgJ
MKI61_RS14170	COG3942	CHAP domain
MKI61_RS14175	COG1535	isochorismatase
MKI61_RS14175	COG3433	isochorismatase activity
MKI61_RS14190	COG0438	transferase activity, transferring glycosyl groups
MKI61_RS14205	COG1073	alpha beta
MKI61_RS14225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKI61_RS14245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKI61_RS14330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKI61_RS14415	COG0471	metal ion transport
MKI61_RS14420	COG2962	Rard protein
MKI61_RS14430	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MKI61_RS14445	COG1136	(ABC) transporter
MKI61_RS14450	COG0577	efflux transmembrane transporter activity
MKI61_RS14460	COG1278	Cold shock
MKI61_RS14480	COG1475	DNA binding
MKI61_RS14550	COG0604	alcohol dehydrogenase
MKI61_RS14570	COG3682	Transcriptional regulator
MKI61_RS14620	COG0577	efflux transmembrane transporter activity
MKI61_RS14620	COG1136	(ABC) transporter