locus-tag	class	description
MKI57_RS00015	COG2501	S4 domain
MKI57_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MKI57_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKI57_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MKI57_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
MKI57_RS00110	COG4863	YycH protein
MKI57_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MKI57_RS00125	COG0737	Belongs to the 5'-nucleotidase family
MKI57_RS00150	COG3425	synthase
MKI57_RS00155	COG0584	glycerophosphoryl diester phosphodiesterase
MKI57_RS00160	COG2030	dehydratase
MKI57_RS00230	COG3732	PTS system glucitol sorbitol-specific
MKI57_RS00235	COG3730	PTS system glucitol sorbitol-specific
MKI57_RS00300	COG0730	response to heat
MKI57_RS00305	COG1937	Protein conserved in bacteria
MKI57_RS00310	COG2210	Belongs to the sulfur carrier protein TusA family
MKI57_RS00315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKI57_RS00355	COG0823	Involved in the tonB-independent uptake of proteins
MKI57_RS00390	COG1473	amidohydrolase
MKI57_RS00400	COG1283	sodium-dependent phosphate transmembrane transporter activity
MKI57_RS00405	COG4716	Myosin-crossreactive antigen
MKI57_RS00410	COG0697	spore germination
MKI57_RS00425	COG1620	l-lactate permease
MKI57_RS00440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI57_RS00445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI57_RS00450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKI57_RS00460	COG2423	ornithine cyclodeaminase activity
MKI57_RS00465	COG4264	IucA IucC family
MKI57_RS00470	COG2814	Major facilitator Superfamily
MKI57_RS00475	COG4264	IucA IucC family
MKI57_RS00480	COG4264	IucA IucC family
MKI57_RS00490	COG0019	diaminopimelate decarboxylase activity
MKI57_RS00495	COG1475	DNA binding
MKI57_RS00515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKI57_RS00520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MKI57_RS00525	COG0438	transferase activity, transferring glycosyl groups
MKI57_RS00560	COG0813	purine-nucleoside phosphorylase activity
MKI57_RS00565	COG2814	Major facilitator Superfamily
MKI57_RS00585	COG3639	organic phosphonate transmembrane transporter activity
MKI57_RS00605	COG0737	Belongs to the 5'-nucleotidase family
MKI57_RS00620	COG1454	alcohol dehydrogenase
MKI57_RS00620	COG1012	belongs to the aldehyde dehydrogenase family
MKI57_RS00645	COG1086	Polysaccharide biosynthesis protein
MKI57_RS00655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MKI57_RS00685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MKI57_RS00695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MKI57_RS00700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MKI57_RS00710	COG2832	Protein of unknown function (DUF454)
MKI57_RS00745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MKI57_RS00750	COG1960	acyl-CoA dehydrogenase activity
MKI57_RS00755	COG5609	conserved protein (DUF2294)
MKI57_RS00805	COG1114	Component of the transport system for branched-chain amino acids
MKI57_RS00810	COG1335	isochorismatase
MKI57_RS00815	COG3961	Belongs to the TPP enzyme family
MKI57_RS00845	COG1737	Transcriptional regulator
MKI57_RS00870	COG1136	(ABC) transporter
MKI57_RS00875	COG1136	(ABC) transporter
MKI57_RS00875	COG0577	efflux transmembrane transporter activity
MKI57_RS00895	COG1131	(ABC) transporter
MKI57_RS00915	COG0601	transmembrane transport
MKI57_RS00920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKI57_RS00930	COG0405	Gamma-glutamyltransferase
MKI57_RS00950	COG3842	ATPase activity
MKI57_RS00960	COG1175	transmembrane transport
MKI57_RS00965	COG3833	ABC-type maltose transport systems, permease component
MKI57_RS00970	COG0673	inositol 2-dehydrogenase activity
MKI57_RS00975	COG0673	inositol 2-dehydrogenase activity
MKI57_RS00985	COG1755	Isoprenylcysteine carboxyl methyltransferase
MKI57_RS01040	COG0183	Belongs to the thiolase family
MKI57_RS01050	COG1960	acyl-CoA dehydrogenase activity
MKI57_RS01055	COG0318	PFAM AMP-dependent synthetase and ligase
MKI57_RS01070	COG0747	negative chemotaxis
MKI57_RS01075	COG3189	MarR family transcriptional regulator
MKI57_RS01100	COG1263	PTS System
MKI57_RS01100	COG2190	(PTS) system
MKI57_RS01100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI57_RS01105	COG1957	nucleoside hydrolase
MKI57_RS01125	COG3414	Phosphotransferase system galactitol-specific IIB component
MKI57_RS01130	COG3775	system Galactitol-specific IIC component
MKI57_RS01135	COG1063	alcohol dehydrogenase
MKI57_RS01145	COG1063	alcohol dehydrogenase
MKI57_RS01155	COG1063	alcohol dehydrogenase
MKI57_RS01160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKI57_RS01165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKI57_RS01175	COG1063	alcohol dehydrogenase
MKI57_RS01180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKI57_RS01215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKI57_RS01220	COG2190	(PTS) system
MKI57_RS01220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI57_RS01220	COG1263	PTS System
MKI57_RS01225	COG2723	6-phospho-beta-galactosidase activity
MKI57_RS01230	COG2226	methyltransferase
MKI57_RS01285	COG1131	(ABC) transporter
MKI57_RS01305	COG1388	LysM domain
MKI57_RS01305	COG3942	CHAP domain
MKI57_RS01425	COG1114	Component of the transport system for branched-chain amino acids
MKI57_RS01430	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MKI57_RS01435	COG0577	efflux transmembrane transporter activity
MKI57_RS01465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKI57_RS01470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKI57_RS01495	COG3314	Sporulation integral membrane protein YlbJ
MKI57_RS01520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKI57_RS01550	COG3037	sugar-specific permease SgaT UlaA
MKI57_RS01560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKI57_RS01565	COG3711	transcriptional antiterminator
MKI57_RS01585	COG2271	Major facilitator Superfamily
MKI57_RS01590	COG0346	lactoylglutathione lyase activity
MKI57_RS01595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKI57_RS01600	COG0431	NADPH-dependent FMN reductase
MKI57_RS01610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKI57_RS01615	COG2822	iron ion transport
MKI57_RS01625	COG0672	)-iron permease
MKI57_RS01630	COG0805	protein transport
MKI57_RS01635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKI57_RS01645	COG1476	TRANSCRIPTIONal
MKI57_RS01685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MKI57_RS01685	COG0646	methionine synthase
MKI57_RS01690	COG0626	cystathionine gamma-synthase activity
MKI57_RS01695	COG0626	cystathionine gamma-synthase activity
MKI57_RS01700	COG1475	DNA binding
MKI57_RS01705	COG0668	transmembrane transport
MKI57_RS01710	COG4481	Protein conserved in bacteria
MKI57_RS01715	COG0012	GTP binding
MKI57_RS01825	COG1823	symporter activity
MKI57_RS01855	COG2233	PERMEase
MKI57_RS01890	COG3759	membrane
MKI57_RS02050	COG0523	cobalamin synthesis protein
MKI57_RS02075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MKI57_RS02085	COG5609	conserved protein (DUF2294)
MKI57_RS02100	COG1647	Serine aminopeptidase, S33
MKI57_RS02105	COG0733	neurotransmitter:sodium symporter activity
MKI57_RS02110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MKI57_RS02115	COG0626	cystathionine gamma-synthase activity
MKI57_RS02125	COG2011	ABC-type metal ion transport system permease component
MKI57_RS02130	COG1464	Belongs to the NlpA lipoprotein family
MKI57_RS02165	COG0583	DNA-binding transcription factor activity
MKI57_RS02170	COG0070	glutamate synthase
MKI57_RS02170	COG0069	glutamate synthase activity
MKI57_RS02170	COG0067	glutamate synthase
MKI57_RS02175	COG0493	'glutamate synthase
MKI57_RS02185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI57_RS02185	COG1263	PTS System
MKI57_RS02190	COG0366	Alpha amylase catalytic
MKI57_RS02195	COG2188	Transcriptional regulator
MKI57_RS02215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKI57_RS02250	COG1982	Orn Lys Arg decarboxylase major
MKI57_RS02260	COG3870	Protein conserved in bacteria
MKI57_RS02265	COG0470	DNA polymerase III
MKI57_RS02270	COG1774	PSP1 C-terminal conserved region
MKI57_RS02280	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MKI57_RS02290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKI57_RS02300	COG0084	hydrolase, TatD family'
MKI57_RS02305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKI57_RS02315	COG4466	Protein conserved in bacteria
MKI57_RS02325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKI57_RS02330	COG0251	oxidation-reduction process
MKI57_RS02370	COG2244	polysaccharide biosynthetic process
MKI57_RS02375	COG3956	TIGRFAM MazG family protein
MKI57_RS02380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MKI57_RS02390	COG1098	S1 RNA binding domain
MKI57_RS02405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKI57_RS02430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKI57_RS02525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKI57_RS02540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKI57_RS02550	COG3880	PFAM UvrB UvrC protein
MKI57_RS02565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKI57_RS02570	COG4956	integral membrane protein (PIN domain superfamily)
MKI57_RS02590	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKI57_RS02645	COG2813	Specifically methylates the guanine in position
MKI57_RS02685	COG1473	amidohydrolase
MKI57_RS02715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MKI57_RS02720	COG1428	Deoxynucleoside kinase
MKI57_RS02725	COG1428	Deoxynucleoside kinase
MKI57_RS02735	COG0561	phosphatase activity
MKI57_RS02775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MKI57_RS02790	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MKI57_RS02880	COG0095	Lipoate-protein ligase
MKI57_RS02885	COG0083	homoserine kinase activity
MKI57_RS02905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKI57_RS02940	COG0667	Aldo Keto reductase
MKI57_RS02945	COG0655	NAD(P)H dehydrogenase (quinone) activity
MKI57_RS02955	COG1078	dGTPase activity
MKI57_RS02990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKI57_RS02995	COG4139	cobalamin transport
MKI57_RS03045	COG4974	Belongs to the 'phage' integrase family
MKI57_RS03100	COG0803	Belongs to the bacterial solute-binding protein 9 family
MKI57_RS03105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKI57_RS03110	COG1121	(ABC) transporter
MKI57_RS03115	COG1321	iron dependent repressor
MKI57_RS03125	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MKI57_RS03135	COG1682	transport, permease protein
MKI57_RS03140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKI57_RS03150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MKI57_RS03155	COG1686	Belongs to the peptidase S11 family
MKI57_RS03160	COG1132	(ABC) transporter
MKI57_RS03165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKI57_RS03175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKI57_RS03180	COG1120	ATPase activity
MKI57_RS03185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI57_RS03190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI57_RS03195	COG2376	Dihydroxyacetone kinase
MKI57_RS03205	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MKI57_RS03215	COG3949	Membrane
MKI57_RS03235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKI57_RS03250	COG1136	(ABC) transporter
MKI57_RS03255	COG0577	efflux transmembrane transporter activity
MKI57_RS03260	COG1392	Phosphate transport regulator
MKI57_RS03265	COG0306	phosphate transporter
MKI57_RS03270	COG1388	LysM domain
MKI57_RS03270	COG3942	CHAP domain
MKI57_RS03280	COG4977	sequence-specific DNA binding
MKI57_RS03280	COG1917	Cupin 2, conserved barrel domain protein
MKI57_RS03310	COG0583	DNA-binding transcription factor activity
MKI57_RS03315	COG2814	Major facilitator Superfamily
MKI57_RS03320	COG2839	Protein conserved in bacteria
MKI57_RS03350	COG1611	Belongs to the LOG family
MKI57_RS03370	COG4988	ABC transporter
MKI57_RS03375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MKI57_RS03385	COG0523	cobalamin synthesis protein
MKI57_RS03390	COG4989	oxidoreductase activity
MKI57_RS03400	COG0471	metal ion transport
MKI57_RS03405	COG0415	Belongs to the DNA photolyase family
MKI57_RS03435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKI57_RS03440	COG1349	DNA-binding transcription factor activity
MKI57_RS03445	COG1105	Belongs to the carbohydrate kinase PfkB family
MKI57_RS03455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKI57_RS03460	COG1253	flavin adenine dinucleotide binding
MKI57_RS03465	COG0656	L-ascorbic acid biosynthetic process
MKI57_RS03470	COG0463	Glycosyl transferase, family 2
MKI57_RS03505	COG0720	synthase
MKI57_RS03515	COG0512	Glutamine amidotransferase of anthranilate synthase
MKI57_RS03515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKI57_RS03520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKI57_RS03550	COG0488	(ABC) transporter
MKI57_RS03555	COG0514	ATP-dependent DNA helicase (RecQ)
MKI57_RS03560	COG0517	IMP dehydrogenase activity
MKI57_RS03560	COG1125	glycine betaine transport
MKI57_RS03565	COG1174	glycine betaine transport
MKI57_RS03590	COG3104	oligopeptide transport
MKI57_RS03615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKI57_RS03620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKI57_RS03630	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI57_RS03635	COG4605	iron ion homeostasis
MKI57_RS03640	COG4604	ABC transporter, ATP-binding protein
MKI57_RS03645	COG4607	ABC-type enterochelin transport system periplasmic component
MKI57_RS03700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKI57_RS03705	COG1739	Uncharacterized protein family UPF0029
MKI57_RS03715	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MKI57_RS03720	COG1040	competence protein
MKI57_RS03750	COG3942	CHAP domain
MKI57_RS03750	COG1388	LysM domain
MKI57_RS03805	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MKI57_RS03865	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MKI57_RS03870	COG1647	Serine aminopeptidase, S33
MKI57_RS03875	COG0557	exoribonuclease II activity
MKI57_RS03975	COG3728	DNA packaging
MKI57_RS03975	COG5484	DNA packaging
MKI57_RS04005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKI57_RS04010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MKI57_RS04075	COG1278	Cold shock
MKI57_RS04115	COG0406	alpha-ribazole phosphatase activity
MKI57_RS04120	COG1279	arginine transmembrane transporter activity
MKI57_RS04145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKI57_RS04150	COG1393	Belongs to the ArsC family
MKI57_RS04160	COG3878	Protein conserved in bacteria
MKI57_RS04165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKI57_RS04180	COG2011	ABC-type metal ion transport system permease component
MKI57_RS04185	COG1464	Belongs to the NlpA lipoprotein family
MKI57_RS04200	COG0396	ATPase activity
MKI57_RS04205	COG0719	Fe-S assembly protein
MKI57_RS04215	COG0822	iron-sulfur transferase activity
MKI57_RS04235	COG1253	flavin adenine dinucleotide binding
MKI57_RS04250	COG1801	Protein of unknown function DUF72
MKI57_RS04255	COG0730	response to heat
MKI57_RS04270	COG4470	Protein conserved in bacteria
MKI57_RS04290	COG2445	Protein of unknown function DUF86
MKI57_RS04320	COG1696	Membrane protein involved in D-alanine export
MKI57_RS04330	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKI57_RS04335	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MKI57_RS04340	COG4837	Protein of unknown function (DUF1462)
MKI57_RS04345	COG1252	NADH dehydrogenase
MKI57_RS04355	COG0316	Belongs to the HesB IscA family
MKI57_RS04365	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MKI57_RS04370	COG2056	Na+-H+ antiporter family
MKI57_RS04375	COG2050	protein possibly involved in aromatic compounds catabolism
MKI57_RS04430	COG1098	S1 RNA binding domain
MKI57_RS04435	COG1902	pentaerythritol trinitrate reductase activity
MKI57_RS04450	COG0584	glycerophosphoryl diester phosphodiesterase
MKI57_RS04470	COG0398	Pfam SNARE associated Golgi protein
MKI57_RS04510	COG0561	phosphatase activity
MKI57_RS04550	COG1881	PFAM PEBP family protein
MKI57_RS04580	COG0601	transmembrane transport
MKI57_RS04585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKI57_RS04590	COG0444	Belongs to the ABC transporter superfamily
MKI57_RS04595	COG4608	Belongs to the ABC transporter superfamily
MKI57_RS04600	COG4166	transmembrane transport
MKI57_RS04605	COG0747	negative chemotaxis
MKI57_RS04610	COG0444	Belongs to the ABC transporter superfamily
MKI57_RS04615	COG4608	Belongs to the ABC transporter superfamily
MKI57_RS04620	COG0601	transmembrane transport
MKI57_RS04625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKI57_RS04650	COG1164	Oligoendopeptidase f
MKI57_RS04660	COG2346	COG2346, Truncated hemoglobins
MKI57_RS04675	COG2357	RelA SpoT domain protein
MKI57_RS04685	COG0564	pseudouridine synthase activity
MKI57_RS04690	COG2239	Acts as a magnesium transporter
MKI57_RS04695	COG0475	glutathione-regulated potassium exporter activity
MKI57_RS04695	COG0569	domain protein
MKI57_RS04715	COG0628	permease
MKI57_RS04720	COG1115	amino acid carrier protein
MKI57_RS04760	COG0861	Integral membrane protein TerC family
MKI57_RS04780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKI57_RS04785	COG0737	Belongs to the 5'-nucleotidase family
MKI57_RS04800	COG4903	ComK protein
MKI57_RS04815	COG4873	Protein conserved in bacteria
MKI57_RS04870	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MKI57_RS04880	COG2314	TM2 domain
MKI57_RS04885	COG0456	acetyltransferase
MKI57_RS04890	COG1575	Belongs to the MenA family. Type 1 subfamily
MKI57_RS04900	COG1169	isochorismate synthase
MKI57_RS04910	COG2267	carboxylic ester hydrolase activity
MKI57_RS04935	COG0436	Aminotransferase
MKI57_RS04940	COG3594	Acyltransferase
MKI57_RS04970	COG1316	TRANSCRIPTIONal
MKI57_RS05015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKI57_RS05030	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKI57_RS05070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKI57_RS05075	COG4172	Belongs to the ABC transporter superfamily
MKI57_RS05080	COG4721	ABC-type cobalt transport system, permease component
MKI57_RS05095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MKI57_RS05115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MKI57_RS05120	COG1271	oxidase subunit
MKI57_RS05125	COG1294	oxidase, subunit
MKI57_RS05130	COG0569	domain protein
MKI57_RS05195	COG1176	ABC-type spermidine putrescine transport system, permease component I
MKI57_RS05200	COG1177	transmembrane transport
MKI57_RS05205	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MKI57_RS05230	COG0483	inositol monophosphate 1-phosphatase activity
MKI57_RS05240	COG1217	gtp-binding protein TYPA
MKI57_RS05250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKI57_RS05260	COG0772	Belongs to the SEDS family
MKI57_RS05290	COG3679	Belongs to the UPF0342 family
MKI57_RS05310	COG0742	ribosomal rna small subunit methyltransferase
MKI57_RS05365	COG4509	Sortase family
MKI57_RS05380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKI57_RS05410	COG1796	DNA polymerase
MKI57_RS05410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MKI57_RS05435	COG2009	succinate dehydrogenase
MKI57_RS05440	COG1053	succinate dehydrogenase
MKI57_RS05445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MKI57_RS05560	COG1288	antiporter activity
MKI57_RS05595	COG1011	Hydrolase
MKI57_RS05620	COG4839	cell division protein FtsL
MKI57_RS05625	COG0768	penicillin binding
MKI57_RS05640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MKI57_RS05645	COG0849	cell division
MKI57_RS05660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKI57_RS05670	COG0762	integral membrane protein
MKI57_RS05675	COG2302	S4 RNA-binding domain
MKI57_RS05680	COG3599	regulation of cell shape
MKI57_RS05690	COG2514	catechol 2,3-dioxygenase activity
MKI57_RS05705	COG0564	pseudouridine synthase activity
MKI57_RS05715	COG2233	PERMEase
MKI57_RS05760	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MKI57_RS05775	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKI57_RS05780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKI57_RS05790	COG2314	TM2 domain
MKI57_RS05805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKI57_RS05805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKI57_RS05815	COG0631	protein serine/threonine phosphatase activity
MKI57_RS05830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MKI57_RS05845	COG1302	Protein conserved in bacteria
MKI57_RS05890	COG1196	nuclear chromosome segregation
MKI57_RS05895	COG0552	protein localization to endoplasmic reticulum
MKI57_RS05905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKI57_RS05960	COG2348	transferase activity, transferring amino-acyl groups
MKI57_RS05965	COG0758	DNA mediated transformation
MKI57_RS06060	COG0195	Participates in both transcription termination and antitermination
MKI57_RS06065	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MKI57_RS06090	COG0196	riboflavin kinase activity
MKI57_RS06115	COG2188	Transcriptional regulator
MKI57_RS06120	COG0612	Peptidase, M16
MKI57_RS06125	COG0612	Peptidase, M16
MKI57_RS06130	COG0300	oxidoreductase activity
MKI57_RS06150	COG1058	Belongs to the CinA family
MKI57_RS06150	COG1546	Belongs to the CinA family
MKI57_RS06170	COG1692	metallophosphoesterase
MKI57_RS06175	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MKI57_RS06175	COG0674	pyruvate-flavodoxin oxidoreductase activity
MKI57_RS06180	COG1013	pyruvate-flavodoxin oxidoreductase activity
MKI57_RS06215	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKI57_RS06220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MKI57_RS06245	COG1923	regulation of RNA biosynthetic process
MKI57_RS06255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKI57_RS06260	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MKI57_RS06265	COG0789	Transcriptional regulator
MKI57_RS06335	COG1131	(ABC) transporter
MKI57_RS06350	COG2197	response regulator
MKI57_RS06360	COG1525	nuclease
MKI57_RS06375	COG0527	aspartate kinase activity
MKI57_RS06380	COG0460	homoserine dehydrogenase
MKI57_RS06385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKI57_RS06410	COG0833	amino acid
MKI57_RS06440	COG2340	Cysteine-rich secretory protein family
MKI57_RS06475	COG4846	Membrane protein involved in cytochrome C biogenesis
MKI57_RS06495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKI57_RS06505	COG0824	Thioesterase
MKI57_RS06530	COG1115	amino acid carrier protein
MKI57_RS06545	COG0628	permease
MKI57_RS06570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKI57_RS06580	COG1363	Peptidase, m42
MKI57_RS06585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKI57_RS06590	COG0512	Glutamine amidotransferase of anthranilate synthase
MKI57_RS06635	COG0561	phosphatase activity
MKI57_RS06680	COG0704	Plays a role in the regulation of phosphate uptake
MKI57_RS06690	COG0581	inorganic phosphate transmembrane transporter activity
MKI57_RS06695	COG0573	inorganic phosphate transmembrane transporter activity
MKI57_RS06715	COG0488	(ABC) transporter
MKI57_RS06720	COG0527	aspartate kinase activity
MKI57_RS06725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKI57_RS06795	COG4548	von Willebrand factor, type A
MKI57_RS06800	COG0714	Associated with various cellular activities
MKI57_RS06845	COG0671	phosphoesterase, PA-phosphatase related
MKI57_RS06920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKI57_RS06940	COG0531	amino acid
MKI57_RS06955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKI57_RS06960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKI57_RS06975	COG0116	Belongs to the methyltransferase superfamily
MKI57_RS07010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MKI57_RS07010	COG4499	WXG100 protein secretion system (Wss), protein YukC
MKI57_RS07020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKI57_RS07025	COG3935	DnaD domain protein
MKI57_RS07050	COG0438	transferase activity, transferring glycosyl groups
MKI57_RS07055	COG1694	Mazg nucleotide pyrophosphohydrolase
MKI57_RS07060	COG2738	Putative neutral zinc metallopeptidase
MKI57_RS07065	COG4347	Protein of unknown function (DUF1405)
MKI57_RS07105	COG0142	geranyltranstransferase activity
MKI57_RS07160	COG0492	ferredoxin-NADP+ reductase activity
MKI57_RS07175	COG0514	ATP-dependent DNA helicase (RecQ)
MKI57_RS07185	COG1141	Ferredoxin
MKI57_RS07230	COG0745	RESPONSE REGULATOR receiver
MKI57_RS07235	COG1187	pseudouridine synthase activity
MKI57_RS07260	COG0735	belongs to the Fur family
MKI57_RS07265	COG0494	nUDIX hydrolase
MKI57_RS07270	COG0667	Aldo Keto reductase
MKI57_RS07280	COG4221	oxidoreductase activity
MKI57_RS07295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKI57_RS07305	COG0366	Alpha amylase catalytic
MKI57_RS07310	COG1609	Transcriptional regulator
MKI57_RS07335	COG2195	Cleaves the N-terminal amino acid of tripeptides
MKI57_RS07345	COG4129	membrane
MKI57_RS07355	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKI57_RS07360	COG0022	dehydrogenase e1 component
MKI57_RS07365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MKI57_RS07370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKI57_RS07375	COG0497	DNA recombination
MKI57_RS07405	COG1302	Protein conserved in bacteria
MKI57_RS07410	COG0439	Biotin carboxylase
MKI57_RS07415	COG0511	ligase activity, forming carbon-carbon bonds
MKI57_RS07425	COG0006	proline dipeptidase activity
MKI57_RS07440	COG0095	Lipoate-protein ligase
MKI57_RS07445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKI57_RS07490	COG4537	Required for transformation and DNA binding
MKI57_RS07495	COG1459	type II secretion system
MKI57_RS07500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKI57_RS07505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKI57_RS07510	COG0011	TIGRFAM Protein of
MKI57_RS07515	COG1940	carbohydrate kinase activity
MKI57_RS07520	COG4483	Protein conserved in bacteria
MKI57_RS07530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKI57_RS07540	COG0768	penicillin binding
MKI57_RS07555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKI57_RS07560	COG1121	(ABC) transporter
MKI57_RS07570	COG0513	Belongs to the DEAD box helicase family
MKI57_RS07580	COG2384	SAM-dependent methyltransferase
MKI57_RS07600	COG0517	IMP dehydrogenase activity
MKI57_RS07620	COG0295	cytidine deaminase activity
MKI57_RS07635	COG1702	phosphate starvation-inducible protein PhoH
MKI57_RS07650	COG1030	water channel activity
MKI57_RS07660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKI57_RS07665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MKI57_RS07695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MKI57_RS07710	COG1466	dna polymerase III delta subunit
MKI57_RS07715	COG2333	competence protein COMEC
MKI57_RS07715	COG0658	competence protein
MKI57_RS07720	COG2131	deaminase
MKI57_RS07725	COG2183	response to ionizing radiation
MKI57_RS07730	COG2226	methyltransferase
MKI57_RS07735	COG0799	negative regulation of ribosome biogenesis
MKI57_RS07740	COG1713	HD superfamily hydrolase involved in NAD metabolism
MKI57_RS07750	COG1534	Rna-binding protein
MKI57_RS07760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKI57_RS07765	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MKI57_RS07785	COG3177	Filamentation induced by cAMP protein fic
MKI57_RS07790	COG1914	H( )-stimulated, divalent metal cation uptake system
MKI57_RS07800	COG0439	Biotin carboxylase
MKI57_RS07805	COG0511	ligase activity, forming carbon-carbon bonds
MKI57_RS07810	COG1984	allophanate hydrolase subunit 2
MKI57_RS07815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MKI57_RS07830	COG0826	peptidase U32
MKI57_RS07835	COG0826	peptidase U32
MKI57_RS07865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MKI57_RS07880	COG1104	cysteine desulfurase activity
MKI57_RS07885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKI57_RS07895	COG3237	CsbD-like
MKI57_RS07900	COG1959	2 iron, 2 sulfur cluster binding
MKI57_RS07905	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MKI57_RS07910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MKI57_RS07955	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MKI57_RS07955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MKI57_RS07960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKI57_RS07960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKI57_RS07965	COG1862	Preprotein translocase
MKI57_RS08005	COG2868	ribosomal protein
MKI57_RS08050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MKI57_RS08055	COG0285	dihydrofolate synthase activity
MKI57_RS08065	COG2818	Glycosylase
MKI57_RS08100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MKI57_RS08135	COG4112	unkown
MKI57_RS08155	COG0833	amino acid
MKI57_RS08170	COG1484	DNA-dependent DNA replication
MKI57_RS08200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKI57_RS08200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKI57_RS08210	COG5002	protein histidine kinase activity
MKI57_RS08215	COG0745	RESPONSE REGULATOR receiver
MKI57_RS08225	COG0372	Belongs to the citrate synthase family
MKI57_RS08230	COG1113	amino acid transport
MKI57_RS08255	COG0281	malic enzyme
MKI57_RS08265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MKI57_RS08270	COG4109	DRTGG domain
MKI57_RS08310	COG0827	DNA restriction-modification system
MKI57_RS08320	COG0730	response to heat
MKI57_RS08330	COG1104	cysteine desulfurase activity
MKI57_RS08345	COG1956	GAF domain-containing protein
MKI57_RS08355	COG0584	glycerophosphoryl diester phosphodiesterase
MKI57_RS08360	COG1764	response to oxidative stress
MKI57_RS08365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MKI57_RS08370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MKI57_RS08385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI57_RS08385	COG1263	PTS System
MKI57_RS08390	COG0204	Acyl-transferase
MKI57_RS08395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKI57_RS08430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MKI57_RS08435	COG0454	-acetyltransferase
MKI57_RS08455	COG1605	Chorismate mutase
MKI57_RS08455	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MKI57_RS08480	COG1674	ftsk spoiiie
MKI57_RS08485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKI57_RS08495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKI57_RS08500	COG1363	Peptidase, m42
MKI57_RS08510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKI57_RS08520	COG0510	thiamine kinase activity
MKI57_RS08540	COG1187	pseudouridine synthase activity
MKI57_RS08545	COG2244	polysaccharide biosynthetic process
MKI57_RS08550	COG2081	HI0933 family
MKI57_RS08570	COG2814	Major facilitator Superfamily
MKI57_RS08575	COG1242	4 iron, 4 sulfur cluster binding
MKI57_RS08580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MKI57_RS08590	COG2267	carboxylic ester hydrolase activity
MKI57_RS08620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKI57_RS08620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKI57_RS08640	COG3266	domain, Protein
MKI57_RS08640	COG5632	N-Acetylmuramoyl-L-alanine amidase
MKI57_RS08640	COG4193	domain, Protein
MKI57_RS08670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKI57_RS08695	COG0656	L-ascorbic acid biosynthetic process
MKI57_RS08715	COG1506	peptidase
MKI57_RS08720	COG2816	NAD+ diphosphatase activity
MKI57_RS08965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MKI57_RS08995	COG1131	(ABC) transporter
MKI57_RS09000	COG0537	adenosine 5'-monophosphoramidase activity
MKI57_RS09030	COG0420	3'-5' exonuclease activity
MKI57_RS09055	COG2197	response regulator
MKI57_RS09060	COG2203	Gaf domain
MKI57_RS09060	COG4585	Histidine kinase
MKI57_RS09065	COG0564	pseudouridine synthase activity
MKI57_RS09095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKI57_RS09100	COG1126	abc transporter atp-binding protein
MKI57_RS09105	COG0765	amino acid transport
MKI57_RS09285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MKI57_RS09290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MKI57_RS09300	COG4129	membrane
MKI57_RS09325	COG1988	membrane-bound metal-dependent
MKI57_RS09335	COG1134	teichoic acid transport
MKI57_RS09335	COG1388	LysM domain
MKI57_RS09380	COG1388	LysM domain
MKI57_RS09380	COG5632	N-Acetylmuramoyl-L-alanine amidase
MKI57_RS09590	COG1484	DNA-dependent DNA replication
MKI57_RS09700	COG4974	Belongs to the 'phage' integrase family
MKI57_RS09705	COG0535	radical SAM domain protein
MKI57_RS09710	COG1607	acyl-coa hydrolase
MKI57_RS09715	COG2309	aminopeptidase activity
MKI57_RS09735	COG1295	ribonuclease BN
MKI57_RS09850	COG4851	CamS sex pheromone cAM373 precursor
MKI57_RS09870	COG4496	protein, YerC YecD
MKI57_RS09905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKI57_RS09915	COG0077	Prephenate dehydratase
MKI57_RS09935	COG1335	isochorismatase
MKI57_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
MKI57_RS10005	COG1131	(ABC) transporter
MKI57_RS10020	COG1725	Transcriptional regulator
MKI57_RS10070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKI57_RS10115	COG5484	DNA packaging
MKI57_RS10115	COG3728	DNA packaging
MKI57_RS10200	COG0582	viral genome integration into host DNA
MKI57_RS10265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKI57_RS10270	COG1621	beta-fructofuranosidase activity
MKI57_RS10275	COG1609	Transcriptional regulator
MKI57_RS10280	COG0004	ammonium transporteR
MKI57_RS10285	COG0425	Belongs to the sulfur carrier protein TusA family
MKI57_RS10290	COG2391	methyltransferase activity
MKI57_RS10300	COG0488	(ABC) transporter
MKI57_RS10310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKI57_RS10320	COG0456	acetyltransferase
MKI57_RS10325	COG1214	PFAM Peptidase M22, glycoprotease
MKI57_RS10330	COG0802	atpase or kinase
MKI57_RS10345	COG0028	Belongs to the TPP enzyme family
MKI57_RS10415	COG2183	response to ionizing radiation
MKI57_RS10420	COG1191	sigma factor activity
MKI57_RS10430	COG1366	Belongs to the anti-sigma-factor antagonist family
MKI57_RS10435	COG2208	phosphoserine phosphatase activity
MKI57_RS10465	COG3428	Bacterial PH domain
MKI57_RS10495	COG2205	protein histidine kinase activity
MKI57_RS10500	COG0745	RESPONSE REGULATOR receiver
MKI57_RS10520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MKI57_RS10530	COG0772	Belongs to the SEDS family
MKI57_RS10545	COG1937	Protein conserved in bacteria
MKI57_RS10555	COG1418	mRNA catabolic process
MKI57_RS10590	COG0629	single-stranded DNA binding
MKI57_RS10665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MKI57_RS10690	COG0009	L-threonylcarbamoyladenylate synthase
MKI57_RS10695	COG2890	protein-(glutamine-N5) methyltransferase activity
MKI57_RS10715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKI57_RS10755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKI57_RS10800	COG0813	purine-nucleoside phosphorylase activity
MKI57_RS10805	COG0783	Belongs to the Dps family
MKI57_RS10825	COG1482	cell wall glycoprotein biosynthetic process
MKI57_RS10830	COG0702	epimerase
MKI57_RS10835	COG0640	Transcriptional regulator
MKI57_RS10865	COG0561	phosphatase activity
MKI57_RS10870	COG1119	ATPase activity
MKI57_RS10885	COG3711	transcriptional antiterminator
MKI57_RS10915	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKI57_RS10985	COG0489	protein tyrosine kinase activity
MKI57_RS10990	COG2814	Major facilitator Superfamily
MKI57_RS11005	COG1272	protein, Hemolysin III
MKI57_RS11015	COG1988	membrane-bound metal-dependent
MKI57_RS11025	COG3314	Sporulation integral membrane protein YlbJ
MKI57_RS11030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI57_RS11035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKI57_RS11040	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MKI57_RS11050	COG3457	Alanine racemase
MKI57_RS11055	COG4264	IucA IucC family
MKI57_RS11060	COG2814	Major facilitator Superfamily
MKI57_RS11085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKI57_RS11095	COG2130	NADP-dependent
MKI57_RS11160	COG0656	L-ascorbic acid biosynthetic process
MKI57_RS11165	COG0789	Transcriptional regulator
MKI57_RS11175	COG5492	domain, Protein
MKI57_RS11195	COG3527	Alpha-acetolactate decarboxylase
MKI57_RS11200	COG0028	Belongs to the TPP enzyme family
MKI57_RS11320	COG0201	protein transport
MKI57_RS11435	COG2252	PERMEase
MKI57_RS11480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKI57_RS11540	COG1763	Mo-molybdopterin cofactor biosynthetic process
MKI57_RS11560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MKI57_RS11565	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MKI57_RS11570	COG4149	molybdate abc transporter
MKI57_RS11575	COG0725	ABC transporter, periplasmic molybdate-binding protein
MKI57_RS11590	COG1268	BioY protein
MKI57_RS11605	COG1960	acyl-CoA dehydrogenase activity
MKI57_RS11610	COG4413	Urea transporter
MKI57_RS11670	COG3942	CHAP domain
MKI57_RS11680	COG1757	Na H antiporter
MKI57_RS11695	COG3942	CHAP domain
MKI57_RS11760	COG1113	amino acid transport
MKI57_RS11780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MKI57_RS11785	COG0385	Bile acid
MKI57_RS11795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI57_RS11795	COG1263	PTS System
MKI57_RS11800	COG1737	Transcriptional regulator
MKI57_RS11820	COG1028	Short-chain dehydrogenase reductase Sdr
MKI57_RS11825	COG1473	amidohydrolase
MKI57_RS11840	COG0583	DNA-binding transcription factor activity
MKI57_RS11865	COG2258	MOSC domain
MKI57_RS11885	COG1668	transmembrane transport
MKI57_RS11895	COG3152	Membrane
MKI57_RS11905	COG0786	glutamate:sodium symporter activity
MKI57_RS11915	COG0598	Magnesium transport protein CorA
MKI57_RS11930	COG0657	acetylesterase activity
MKI57_RS11940	COG2814	Major facilitator Superfamily
MKI57_RS11945	COG1566	PFAM secretion protein HlyD family protein
MKI57_RS11955	COG2814	Major facilitator Superfamily
MKI57_RS12015	COG1620	l-lactate permease
MKI57_RS12035	COG0604	alcohol dehydrogenase
MKI57_RS12060	COG1511	domain protein
MKI57_RS12075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKI57_RS12075	COG1263	PTS System
MKI57_RS12090	COG3871	stress protein (general stress protein 26)
MKI57_RS12130	COG0789	Transcriptional regulator
MKI57_RS12150	COG2181	nitrate reductase activity
MKI57_RS12160	COG1140	nitrate reductase beta subunit
MKI57_RS12165	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKI57_RS12175	COG2146	nitrite reductase [NAD(P)H] activity
MKI57_RS12180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKI57_RS12190	COG0454	-acetyltransferase
MKI57_RS12195	COG2116	formate transmembrane transporter activity
MKI57_RS12210	COG3443	Belongs to the bacterial solute-binding protein 9 family
MKI57_RS12210	COG0803	Belongs to the bacterial solute-binding protein 9 family
MKI57_RS12250	COG1126	abc transporter atp-binding protein
MKI57_RS12255	COG0765	amino acid transport
MKI57_RS12260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKI57_RS12265	COG2814	Major facilitator Superfamily
MKI57_RS12280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKI57_RS12320	COG0156	8-amino-7-oxononanoate synthase activity
MKI57_RS12330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MKI57_RS12335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MKI57_RS12345	COG1132	(ABC) transporter
MKI57_RS12350	COG1132	(ABC) transporter
MKI57_RS12350	COG2375	cellular response to nickel ion
MKI57_RS12365	COG1929	Belongs to the glycerate kinase type-1 family
MKI57_RS12375	COG2814	Major facilitator Superfamily
MKI57_RS12395	COG1113	amino acid transport
MKI57_RS12405	COG0531	amino acid
MKI57_RS12420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKI57_RS12430	COG1174	glycine betaine transport
MKI57_RS12440	COG1174	glycine betaine transport
MKI57_RS12460	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MKI57_RS12465	COG0531	amino acid
MKI57_RS12470	COG2272	Belongs to the type-B carboxylesterase lipase family
MKI57_RS12475	COG2814	Major facilitator Superfamily
MKI57_RS12480	COG0390	transport system, permease component
MKI57_RS12485	COG4619	ABC transporter
MKI57_RS12490	COG1363	Peptidase, m42
MKI57_RS12505	COG4808	Protein conserved in bacteria
MKI57_RS12510	COG0069	glutamate synthase activity
MKI57_RS12565	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MKI57_RS12570	COG1028	Short-chain dehydrogenase reductase Sdr
MKI57_RS12575	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MKI57_RS12580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKI57_RS12670	COG0494	nUDIX hydrolase
MKI57_RS12710	COG1846	Transcriptional regulator
MKI57_RS12740	COG1070	Carbohydrate kinase
MKI57_RS12745	COG1802	Transcriptional regulator
MKI57_RS12750	COG0789	Transcriptional regulator
MKI57_RS12755	COG2357	RelA SpoT domain protein
MKI57_RS12760	COG4876	unkown
MKI57_RS12770	COG2271	Major facilitator Superfamily
MKI57_RS12775	COG0586	Pfam SNARE associated Golgi protein
MKI57_RS12785	COG1131	(ABC) transporter
MKI57_RS12800	COG3949	Membrane
MKI57_RS12805	COG0400	carboxylic ester hydrolase activity
MKI57_RS12810	COG0346	lactoylglutathione lyase activity
MKI57_RS12815	COG1846	Transcriptional regulator
MKI57_RS12825	COG2514	catechol 2,3-dioxygenase activity
MKI57_RS12840	COG0561	phosphatase activity
MKI57_RS12845	COG1131	(ABC) transporter
MKI57_RS12855	COG3764	Sortase (surface protein transpeptidase)
MKI57_RS12875	COG1760	l-serine dehydratase
MKI57_RS12880	COG1760	l-serine dehydratase
MKI57_RS12895	COG0697	spore germination
MKI57_RS12900	COG0657	acetylesterase activity
MKI57_RS12920	COG0028	Belongs to the TPP enzyme family
MKI57_RS12935	COG0583	DNA-binding transcription factor activity
MKI57_RS12945	COG3942	CHAP domain
MKI57_RS12955	COG3425	synthase
MKI57_RS12960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKI57_RS12985	COG2409	Drug exporters of the RND superfamily
MKI57_RS13040	COG0436	Aminotransferase
MKI57_RS13070	COG3942	CHAP domain
MKI57_RS13075	COG2755	lipolytic protein G-D-S-L family
MKI57_RS13075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MKI57_RS13190	COG0456	acetyltransferase
MKI57_RS13235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKI57_RS13245	COG1279	arginine transmembrane transporter activity
MKI57_RS13265	COG3173	Aminoglycoside phosphotransferase
MKI57_RS13320	COG0456	acetyltransferase
MKI57_RS13330	COG2378	regulation of single-species biofilm formation
MKI57_RS13415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MKI57_RS13420	COG2801	Transposase and inactivated derivatives
MKI57_RS13480	COG0456	acetyltransferase
MKI57_RS13525	COG3409	Peptidoglycan-binding domain 1 protein
MKI57_RS13540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKI57_RS13680	COG4115	mRNA cleavage
MKI57_RS13695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKI57_RS13715	COG1192	Involved in chromosome partitioning
MKI57_RS13765	COG2226	methyltransferase
MKI57_RS13775	COG0456	acetyltransferase
MKI57_RS13845	COG3001	Fructosamine kinase
MKI57_RS13850	COG0167	dihydroorotate dehydrogenase activity
MKI57_RS13905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKI57_RS13910	COG3527	Alpha-acetolactate decarboxylase
MKI57_RS13920	COG0531	amino acid
MKI57_RS13950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MKI57_RS13970	COG1012	belongs to the aldehyde dehydrogenase family
MKI57_RS13980	COG1510	regulation of RNA biosynthetic process
MKI57_RS13985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKI57_RS14010	COG2851	Citrate transporter
MKI57_RS14025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKI57_RS14035	COG0386	Belongs to the glutathione peroxidase family
MKI57_RS14055	COG1136	(ABC) transporter
MKI57_RS14060	COG2205	protein histidine kinase activity
MKI57_RS14065	COG0745	RESPONSE REGULATOR receiver
MKI57_RS14075	COG1785	Belongs to the alkaline phosphatase family
MKI57_RS14085	COG1846	Transcriptional regulator
MKI57_RS14130	COG1438	arginine binding
MKI57_RS14150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKI57_RS14150	COG3711	transcriptional antiterminator
MKI57_RS14155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKI57_RS14155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKI57_RS14155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKI57_RS14160	COG1482	cell wall glycoprotein biosynthetic process
MKI57_RS14170	COG1705	Flagellar rod assembly protein muramidase FlgJ
MKI57_RS14170	COG3942	CHAP domain
MKI57_RS14175	COG1535	isochorismatase
MKI57_RS14175	COG3433	isochorismatase activity
MKI57_RS14190	COG0438	transferase activity, transferring glycosyl groups
MKI57_RS14205	COG1073	alpha beta
MKI57_RS14225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKI57_RS14245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKI57_RS14330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKI57_RS14415	COG0471	metal ion transport
MKI57_RS14420	COG2962	Rard protein
MKI57_RS14430	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MKI57_RS14445	COG1136	(ABC) transporter
MKI57_RS14450	COG0577	efflux transmembrane transporter activity
MKI57_RS14460	COG1278	Cold shock
MKI57_RS14480	COG1475	DNA binding
MKI57_RS14550	COG0604	alcohol dehydrogenase
MKI57_RS14570	COG3682	Transcriptional regulator
MKI57_RS14620	COG0577	efflux transmembrane transporter activity
MKI57_RS14620	COG1136	(ABC) transporter